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Search of human proteins with 62912462
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62912462 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
(251 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62912466 complement component 4 binding protein, beta chain i... 540 e-154
gi|62912462 complement component 4 binding protein, beta chain i... 540 e-154
gi|62912468 complement component 4 binding protein, beta chain i... 535 e-152
gi|62912464 complement component 4 binding protein, beta chain i... 535 e-152
gi|4502505 complement component 4 binding protein, beta chain is... 535 e-152
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 123 2e-28
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 103 1e-22
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 103 1e-22
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 103 1e-22
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 100 2e-21
gi|148886654 polydom [Homo sapiens] 97 2e-20
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 91 1e-18
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 89 5e-18
gi|67782358 complement factor B preproprotein [Homo sapiens] 88 6e-18
gi|187960042 selectin E precursor [Homo sapiens] 87 2e-17
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 83 2e-16
gi|157419154 selectin P precursor [Homo sapiens] 80 1e-15
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 80 2e-15
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 78 6e-15
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 78 6e-15
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 77 1e-14
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 77 1e-14
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 77 1e-14
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 77 1e-14
gi|4502503 complement component 4 binding protein, alpha chain p... 71 8e-13
gi|14550407 complement component 2 isoform 1 preproprotein [Homo... 70 2e-12
gi|168693643 decay accelerating factor for complement isoform 2 ... 68 7e-12
gi|10835143 decay accelerating factor for complement isoform 1 p... 68 7e-12
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 68 7e-12
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 68 7e-12
>gi|62912466 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 540 bits (1390), Expect = e-154
Identities = 251/251 (100%), Positives = 251/251 (100%)
Query: 1 MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTL 60
MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTL
Sbjct: 1 MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTL 60
Query: 61 FCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC 120
FCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC
Sbjct: 61 FCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC 120
Query: 121 LEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD 180
LEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD
Sbjct: 121 LEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD 180
Query: 181 GEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLE 240
GEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLE
Sbjct: 181 GEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLE 240
Query: 241 LKKAELKAKLL 251
LKKAELKAKLL
Sbjct: 241 LKKAELKAKLL 251
>gi|62912462 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 540 bits (1390), Expect = e-154
Identities = 251/251 (100%), Positives = 251/251 (100%)
Query: 1 MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTL 60
MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTL
Sbjct: 1 MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTL 60
Query: 61 FCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC 120
FCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC
Sbjct: 61 FCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC 120
Query: 121 LEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD 180
LEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD
Sbjct: 121 LEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD 180
Query: 181 GEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLE 240
GEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLE
Sbjct: 181 GEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLE 240
Query: 241 LKKAELKAKLL 251
LKKAELKAKLL
Sbjct: 241 LKKAELKAKLL 251
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 535 bits (1378), Expect = e-152
Identities = 251/252 (99%), Positives = 251/252 (99%), Gaps = 1/252 (0%)
Query: 1 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 59
MFFWCACCLMVAWRVSASD EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
Query: 60 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 119
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
Query: 120 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 179
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
Query: 180 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 239
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
Query: 240 ELKKAELKAKLL 251
ELKKAELKAKLL
Sbjct: 241 ELKKAELKAKLL 252
>gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 535 bits (1378), Expect = e-152
Identities = 251/252 (99%), Positives = 251/252 (99%), Gaps = 1/252 (0%)
Query: 1 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 59
MFFWCACCLMVAWRVSASD EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
Query: 60 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 119
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
Query: 120 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 179
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
Query: 180 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 239
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
Query: 240 ELKKAELKAKLL 251
ELKKAELKAKLL
Sbjct: 241 ELKKAELKAKLL 252
>gi|4502505 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 535 bits (1378), Expect = e-152
Identities = 251/252 (99%), Positives = 251/252 (99%), Gaps = 1/252 (0%)
Query: 1 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 59
MFFWCACCLMVAWRVSASD EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
Query: 60 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 119
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
Query: 120 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 179
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
Query: 180 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 239
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
Query: 240 ELKKAELKAKLL 251
ELKKAELKAKLL
Sbjct: 241 ELKKAELKAKLL 252
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 123 bits (308), Expect = 2e-28
Identities = 66/183 (36%), Positives = 93/183 (50%), Gaps = 7/183 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKIT 103
+ C GY LVG C A+ W + T C GHC PDP+ VNG S G + D +
Sbjct: 2647 FTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPI-VNGHISGDG-FSYRDTVV 2704
Query: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 163
+ CN + L G++ CL+DH W+ P+C C PGNP HG+ G+ F L +++
Sbjct: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFT 2764
Query: 164 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFM 222
C Y L GV QC +G+WSS LP C+++ + E A+ Q+ N E+ E M
Sbjct: 2765 CNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ--NFPESFEYGM 2822
Query: 223 QQL 225
L
Sbjct: 2823 SIL 2825
Score = 83.6 bits (205), Expect = 2e-16
Identities = 48/157 (30%), Positives = 73/157 (46%), Gaps = 14/157 (8%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-----VLVNGEFSSSGPVNVSD 100
Y C KG++L+G L C A+ WD + +C C P ++ GE + G V
Sbjct: 2826 YHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAV---- 2881
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD---CDPPGNPVHGYFEGNNFTLG 157
+ + C L G++ C ED W+ P C + C PG P HG G++F
Sbjct: 2882 -VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK 2940
Query: 158 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
S + + CE + L G E+ C ++G WS PVC+ +
Sbjct: 2941 SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2977
Score = 79.3 bits (194), Expect = 3e-15
Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 6/151 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV-----NGEFSSSGPVNVSD 100
+ C GY L G C ++ +W + CR+ +C DP V +G+ +
Sbjct: 2763 FTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGM 2822
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 160
I + C + L GS+ C+ + W P C + C PG P + G FT G+ +
Sbjct: 2823 SILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVV 2882
Query: 161 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Y C L+G + C D WS ALP C
Sbjct: 2883 HYSCRGSESLIGNDTRVCQEDSHWSGALPHC 2913
Score = 77.0 bits (188), Expect = 1e-14
Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 5/174 (2%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
CP+ PPV N + +Y C+ GY L L C W +C C
Sbjct: 3098 CPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCG 3157
Query: 82 DPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRDC 138
DP + S ++ F C +IL GS+R C D TW+ P C C
Sbjct: 3158 DPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTC 3217
Query: 139 DPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 190
PG P G + + +GST+ + C Y++ G + C+ WS C
Sbjct: 3218 PDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTEC 3271
Score = 75.1 bits (183), Expect = 5e-14
Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 5/158 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 104
+ C G+ L G C + W C C +P NG SS + S + +
Sbjct: 2945 FSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
C + Y G C + TW P C C PG +G G +FT T+SY C
Sbjct: 3005 ACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQC 3064
Query: 165 EDRYYLVGVQEQ--QCV-DGEWSSALPVCKLIQEAPKP 199
Y + V +C DG W+ + PVCK + P+P
Sbjct: 3065 NPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVL-CPQP 3101
Score = 74.3 bits (181), Expect = 9e-14
Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 3/149 (2%)
Query: 45 TYVCIKGYHL--VGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 102
+Y C GY + V T+ C W+ + C+ CP P V I
Sbjct: 3061 SYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSI 3120
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
++ C D Y L S C W P C C PG P G G +FT S + +
Sbjct: 3121 SYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFF 3180
Query: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
C+ + LVG + C DG WS P C
Sbjct: 3181 QCKSPFILVGSSRRVCQADGTWSGIQPTC 3209
Score = 67.4 bits (163), Expect = 1e-11
Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 5/153 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVNGEFSSSGPVNVSDKI 102
Y C L+G T C W C G C DP +
Sbjct: 2884 YSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLL 2943
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYF-EGNNFTLGSTIS 161
F C + L+GS CL + +W+ P+C++ C PG P +G + S++
Sbjct: 2944 RFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVI 3003
Query: 162 YYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Y C + Y G+ + C +G W+ P C +I
Sbjct: 3004 YACWEGYKTSGLMTRHCTANGTWTGTAPDCTII 3036
Score = 66.2 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 60/153 (39%), Gaps = 7/153 (4%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVN-GEFSSSGPVNVSDK 101
+ C + LVG C A W C CPDP + G +SS V
Sbjct: 3180 FQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGST 3239
Query: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGSTI 160
+ F C Y ++GS CL + TW+ C C P P H + T G T+
Sbjct: 3240 VFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTL 3299
Query: 161 SYYCEDRYYLVGVQEQQC--VDGEWSSALPVCK 191
Y C ++L G E + D +W+ PVCK
Sbjct: 3300 VYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
Score = 58.5 bits (140), Expect = 5e-09
Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 13/126 (10%)
Query: 75 CRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPF 130
C L H L NG + V K+ + C Y + G + + C + + W
Sbjct: 2433 CSLTH----PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLT 2488
Query: 131 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV---DGEWSS-- 185
P+C++ C P +P +G F GN FTL S + Y C + + L Q+ V DG WS+
Sbjct: 2489 PLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKG 2548
Query: 186 ALPVCK 191
P CK
Sbjct: 2549 KPPTCK 2554
Score = 51.2 bits (121), Expect = 8e-07
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASK----EWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSD 100
Y C GY +VG C + +WD+ T C+ C P NG F+ + +
Sbjct: 2458 YFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGN-EFTLDS 2516
Query: 101 KITFMCNDHYILKGSNRSQ--CLEDHTWA----PPF--PI-CKSRDCDPPGNPVHGYFEG 151
K+ + C++ + L+ S ++ C ED W+ PP P+ C S + + + G
Sbjct: 2517 KVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSG 2576
Query: 152 NNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWS--SALPVCKLI 193
+ G+ + C YYL G + +C +G W+ P C++I
Sbjct: 2577 SLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVI 2621
Score = 48.1 bits (113), Expect = 7e-06
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF--- 104
C KGYH+ G T C A+ W TEC C P E + V D TF
Sbjct: 3244 CRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQP-----ETPAHADVRAIDLPTFGYT 3298
Query: 105 ---MCNDHYILK-GSNRSQCLEDHTWAPPFPICKSR 136
C+ + L GS C D W P+CKS+
Sbjct: 3299 LVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSK 3334
Score = 47.4 bits (111), Expect = 1e-05
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 20/183 (10%)
Query: 23 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKK--TLFCNASKEWDNT--TTECRLG 78
PE P N F E Y C +G+ L + T C W N C+
Sbjct: 2499 PESP--GNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPV 2556
Query: 79 HCPDPVLVNGEFSS-------SGPVN-VSDKITFMCNDHYILKGSNRSQCLEDHTW--AP 128
CP + + S SG +N ++ C+ Y L+G +C + TW
Sbjct: 2557 ACPS---IEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGD 2613
Query: 129 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSAL 187
P C+ C P +G G G+T + C Y LVG ++C+ +G WS +
Sbjct: 2614 ERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSE 2673
Query: 188 PVC 190
C
Sbjct: 2674 TRC 2676
Score = 44.7 bits (104), Expect = 8e-05
Identities = 22/60 (36%), Positives = 36/60 (60%), Gaps = 5/60 (8%)
Query: 137 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVCK 191
+C PG P++G G+ F LGS++S++C+D + G + C+ DG WSS +P C+
Sbjct: 697 ECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE 756
Score = 44.3 bits (103), Expect = 1e-04
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-----EWSSALPVC 190
C PGN ++G G +F LGSTI+Y C+ Y ++ CV G W LP C
Sbjct: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Score = 42.0 bits (97), Expect = 5e-04
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 80 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPFPICK 134
CPDP + NG + S V + F C D+Y+L+GS C W+ PIC+
Sbjct: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 135 SRDC 138
+R C
Sbjct: 409 ARTC 412
Score = 41.6 bits (96), Expect = 7e-04
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
+S C PG PV+G+ G +F + ST+++ C+ Y L + C + +W+ ALP C
Sbjct: 870 ESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC 927
Score = 38.1 bits (87), Expect = 0.007
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 138 CDPPGNPVHGYFEGNNFT-LGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCK 191
C PG P +G G++F+ +G+ + + CED Y L G + C WS P+C+
Sbjct: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Score = 38.1 bits (87), Expect = 0.007
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
C PG P +G G++F G T+++ C + LVG + C + +WS P C
Sbjct: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 36.6 bits (83), Expect = 0.021
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
CD PG P G +F +G ++++ C Y L G + C+ G WS+ LP C
Sbjct: 1046 CDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
Score = 35.4 bits (80), Expect = 0.047
Identities = 18/67 (26%), Positives = 24/67 (35%), Gaps = 5/67 (7%)
Query: 130 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWS 184
+ + S C PG + G G F +G I Y C Y L G C+ W
Sbjct: 137 YEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
Query: 185 SALPVCK 191
P C+
Sbjct: 197 FPAPFCR 203
Score = 35.4 bits (80), Expect = 0.047
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 71 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKIT-FMCNDHYILKGSNRSQCL--EDHTWA 127
T T L C DP + N + + +D + + CN Y + GSN CL + W
Sbjct: 1209 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 1268
Query: 128 PPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
P P C + +C G +H G + G Y
Sbjct: 1269 KPLPSCIA-EC---GGQIHAATSGRILSPGYPAPY 1299
Score = 34.3 bits (77), Expect = 0.11
Identities = 16/59 (27%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPFPIC 133
L C +P L + V+D ++F C Y L+G + C+ W P P+C
Sbjct: 1913 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
Score = 33.9 bits (76), Expect = 0.14
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 190
C+ PG P +G G++ G T+++ C+ Y L G + CV W P C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 33.9 bits (76), Expect = 0.14
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 133
L +CPDP + + +V ++F C YIL G C + W PFP C
Sbjct: 2085 LQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
Score = 32.7 bits (73), Expect = 0.31
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 136 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
++C P +GY +++++G ++S+ C Y L+G C G W+ P C
Sbjct: 2086 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
Score = 32.3 bits (72), Expect = 0.40
Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 10/78 (12%)
Query: 80 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDC 138
C DP + VNG G + +TF C+ Y L C +H W P C +
Sbjct: 874 CLDPGIPVNGH-RHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-- 930
Query: 139 DPPGNPVHGYFEGNNFTL 156
GY +G + T+
Sbjct: 931 ------CGGYIQGKSGTV 942
Score = 31.6 bits (70), Expect = 0.68
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 2/65 (3%)
Query: 71 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 128
T +E L C DP + V D +TF C Y L+G+ + CL W+
Sbjct: 1037 TFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSA 1096
Query: 129 PFPIC 133
P P C
Sbjct: 1097 PLPRC 1101
Score = 31.6 bits (70), Expect = 0.68
Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 2/58 (3%)
Query: 20 EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 75
++CP+ PP N + + ++ C GY L+G L C ++ W+ C
Sbjct: 2086 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
Score = 30.4 bits (67), Expect = 1.5
Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 4/62 (6%)
Query: 18 SDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC----NASKEWDNTTT 73
SD C +P + E + + C GY L G L C NA +W++T
Sbjct: 1738 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
Query: 74 EC 75
C
Sbjct: 1798 SC 1799
Score = 29.6 bits (65), Expect = 2.6
Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT---WAPPFPIC 133
C DP + D +TF C+ Y L+G + C++ + W P P C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 29.3 bits (64), Expect = 3.4
Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 4/43 (9%)
Query: 97 NVSDKITFMCNDHYILKGSNRSQCL----EDHTWAPPFPICKS 135
N+ DKI + C YIL+G C+ +W P P C++
Sbjct: 162 NIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
Score = 27.7 bits (60), Expect = 9.9
Identities = 8/31 (25%), Positives = 15/31 (48%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
T+ C + LVG++ + C + +W C
Sbjct: 551 TFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 27.7 bits (60), Expect = 9.9
Identities = 16/61 (26%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Query: 136 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQC---VDGEWSSALPVC 190
+ C PP E ++F +G + Y C Y LVG C ++ +LP C
Sbjct: 2257 KKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTC 2316
Query: 191 K 191
+
Sbjct: 2317 E 2317
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 103 bits (257), Expect = 1e-22
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
C ELP N + + + C G+ LVG C +S W + T C GHC
Sbjct: 2719 CGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCG 2778
Query: 82 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P ++VNG+ D + + CN + L GS+ C +DH W+ P C C
Sbjct: 2779 IPELIVNGQVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGH 2837
Query: 141 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
PG+P++G GN F +++ C Y + G + QC + +WS P+CK++
Sbjct: 2838 PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2891
Score = 95.9 bits (237), Expect = 3e-20
Identities = 54/173 (31%), Positives = 78/173 (45%), Gaps = 20/173 (11%)
Query: 38 VEGQILG---------TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVL 85
V GQ++G Y C G+ L+G C W C GH P+
Sbjct: 2784 VNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY 2843
Query: 86 VNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPV 145
G S +G N +D +TF CN Y+++G ++QC + W+ P P+CK +C PG P
Sbjct: 2844 --GRTSGNG-FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2900
Query: 146 H----GYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
+ E NFT G+ + Y C Y+L G C +G+W LP C +I
Sbjct: 2901 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI 2953
Score = 91.7 bits (226), Expect = 6e-19
Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 104
Y C GY L G + C A+ W EC+ C +P NG+ S + +
Sbjct: 3040 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 3099
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
C + YIL G + QC + TW+ P C C PG P +G G+++ +G +SY C
Sbjct: 3100 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3159
Query: 165 EDRY--YLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 206
+ Y L G + + C ++G WS +P C+ + P+ L
Sbjct: 3160 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3204
Score = 86.7 bits (213), Expect = 2e-17
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSS---GPVNVSD 100
T+ C GY + G C A+++W + C++ +C DP + N + S G
Sbjct: 2858 TFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGT 2917
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 160
+ + CN Y L GS+ C + W P P C DC PG P + G +T GST+
Sbjct: 2918 VVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTV 2977
Query: 161 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Y C + L+G + C ++G WS + P C
Sbjct: 2978 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3008
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Y C GY L G L C + +WD EC + C P + S + +
Sbjct: 2921 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYS 2980
Query: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICK---SRDCDPPGNPVHGYFEGNNFTLGSTISY 162
C L G + C + W+ P C + C PG P HG + +NF ST+ Y
Sbjct: 2981 CTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRY 3040
Query: 163 YCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 194
C+ Y L G +E+ C+ +G W+ P CK +Q
Sbjct: 3041 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQ 3073
Score = 78.6 bits (192), Expect = 5e-15
Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 7/175 (4%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
CP P + N + +Y+C GY L L C + W +C C
Sbjct: 3193 CPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3252
Query: 82 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRD 137
DP + G+ + S+ ++F CN +IL GS+ C D TW+ P C
Sbjct: 3253 DPGIPAQGKREGKSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTS 3311
Query: 138 CDPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
C+ PG P HG F +GS + ++C+ + L G + C+ D WS P C
Sbjct: 3312 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3366
Score = 78.2 bits (191), Expect = 6e-15
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 7/176 (3%)
Query: 23 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR---LGH 79
P +PP N++ ++ Y C L+G+ + C + W + C G
Sbjct: 2958 PGVPP--NAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 3015
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 139
C DP + + C+ YIL GS CL + +W P CK+ C
Sbjct: 3016 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCG 3075
Query: 140 PPGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
PG +G F + T S++ Y C + Y L G +QC +G WS LP C +I
Sbjct: 3076 NPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTII 3131
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 45 TYVCIKGY--HLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 102
+Y+C GY L G + C + W CR CP P ++ + I
Sbjct: 3156 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSI 3215
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
+++C+ Y L C+ + TW+ P C + C PG P G EG +F S +S+
Sbjct: 3216 SYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSF 3275
Query: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKN 213
C + LVG + C DG WS + P C E + CE + S+N
Sbjct: 3276 SCNFPFILVGSSTRICQADGTWSGSSPHC---IEPTQTSCENPGVPRHGSQN 3324
Score = 73.2 bits (178), Expect = 2e-13
Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDP-VLVNGEFSSSGPVNVSD 100
++ C + LVG T C A W ++ C C +P V +G +++ V
Sbjct: 3274 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3333
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 159
+ F C ++L+GS CL D TW+ P C C P P H G + + G T
Sbjct: 3334 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYT 3393
Query: 160 ISYYCEDRYYLVGVQEQQCV--DGEWSSALPVC----KLIQEAPKP 199
+ Y C+ ++L G E + D W+ +P+C K++ + P+P
Sbjct: 3394 LIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3439
Score = 57.8 bits (138), Expect = 9e-09
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 12/158 (7%)
Query: 45 TYVCIKGYHLVGKK--TLFCNASKEWDN--TTTECRLGHCPDP---VLVNGEFS--SSGP 95
TY C GY L K+ T C + W N T C + CP +L +G + +
Sbjct: 2615 TYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH 2674
Query: 96 VNVSDKITFMCNDHYILKGSNRSQCLEDHTWA--PPFPICKSRDCDPPGNPVHGYFEGNN 153
K+ F C+ Y G +CL + TW+ P C+ C P +G G
Sbjct: 2675 YEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQ 2734
Query: 154 FTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
+ GST + C+ + LVG ++C+ G WS + C
Sbjct: 2735 TSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2772
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 23/197 (11%)
Query: 23 PELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLFCNASK----EWDNTTTECR 76
PE PP ++ + GQ+ + C +G+ LVGK + C S WD C+
Sbjct: 2532 PESPPHG---YIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Query: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL--KGSNRSQCLEDHTWA--PPFPI 132
C P + V ++T+ CND Y L K + C D TW+ P
Sbjct: 2589 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2648
Query: 133 CKSRDCDPPGNPV--HGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWS-- 184
C C + + HG + G+++ + + + C+ Y+ +G +C+ +G WS
Sbjct: 2649 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2708
Query: 185 SALPVCKLIQ--EAPKP 199
+ P C++I E P P
Sbjct: 2709 NERPYCQIISCGELPTP 2725
Score = 48.9 bits (115), Expect = 4e-06
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WSSALPVC 190
C PGN ++G G ++ LGST++YYC+ Y L G C+ G+ W+ ALP C
Sbjct: 1661 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
Score = 48.5 bits (114), Expect = 5e-06
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKL 192
C PG P +G G++F+LGST+ + C++ Y L G + C V WS PVCK+
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-WSSALPVC 190
C PG PVHG G++F++GST+S+ C+ Y L + C WS LP C
Sbjct: 970 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
Score = 45.1 bits (105), Expect = 6e-05
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C+ PG P +G G NF +G T+++ C Y L G E C+ G WS+ LP C
Sbjct: 1142 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
Score = 42.7 bits (99), Expect = 3e-04
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 136 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVCKL 192
+ C P +G+ GN+FT+G TIS+ C Y L+G C+ G W+ LP C+
Sbjct: 2182 QSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2241
Query: 193 I 193
+
Sbjct: 2242 L 2242
Score = 42.0 bits (97), Expect = 5e-04
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 190
+ C PG P++G EG+ F+ + + C+ + L+G + C + +WS+ +P+C
Sbjct: 620 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
Score = 41.2 bits (95), Expect = 9e-04
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 137 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVC 190
+C PG P++ G+NF LGS+IS CE+ + G + C+ DG+ WS +P C
Sbjct: 793 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWSSALP 188
+S C PG P G G F +G I Y C Y L G + C+ W +P
Sbjct: 134 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 193
Query: 189 VCK 191
+C+
Sbjct: 194 ICR 196
Score = 37.4 bits (85), Expect = 0.012
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 138 CDPPGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
C+ PG P GY GSTI Y C Y L G +C+ GE W LP C
Sbjct: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1370
Score = 37.0 bits (84), Expect = 0.016
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 190
C PG P++G G+ G T+ + C+ Y L G + C+ E W + PVC
Sbjct: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
Score = 36.6 bits (83), Expect = 0.021
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
Query: 71 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 128
T +E L C DP + + D +TF C+ Y L+G++ CL W+
Sbjct: 1133 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1192
Query: 129 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
P P C + +C G N+ L ++ C
Sbjct: 1193 PLPRCVA-ECGASATNNEGILLSPNYPLNYENNHEC 1227
Score = 35.8 bits (81), Expect = 0.036
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 2/63 (3%)
Query: 73 TECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPF 130
T L CP+P + V D ++F C+ Y L+G + C+ W P
Sbjct: 2005 TAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPI 2064
Query: 131 PIC 133
PIC
Sbjct: 2065 PIC 2067
Score = 35.0 bits (79), Expect = 0.062
Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE----DHTWAPPFPICKS 135
CPDP ++ + F C++ Y+L+G+ C W+ P+CK
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Query: 136 RDCDPPGNPVHGYFEGNNF 154
+ C G F NF
Sbjct: 506 KTCGSNLQGPSGTFTSPNF 524
Score = 34.7 bits (78), Expect = 0.081
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 131 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSS 185
P S C P G GN F +GS++ + C Y L G +C +W+
Sbjct: 1831 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1890
Query: 186 ALPVC 190
+LP C
Sbjct: 1891 SLPTC 1895
Score = 34.3 bits (77), Expect = 0.11
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 76 RLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 133
+L CPDP F V I+F C Y L G++ CL W P P C
Sbjct: 2180 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2239
Query: 134 KS 135
++
Sbjct: 2240 EA 2241
Score = 33.9 bits (76), Expect = 0.14
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 73 TECRLGHCPDPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRSQCL--EDHTWAPP 129
T L HC DP + + S + + I + CN Y L GS+ +C+ E W P
Sbjct: 1307 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYP 1366
Query: 130 FPIC 133
P C
Sbjct: 1367 LPSC 1370
Score = 33.5 bits (75), Expect = 0.18
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 97 NVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFPICKSRD 137
+V DKI + C YIL G + C+ + +W P PIC++ D
Sbjct: 155 DVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
Score = 33.5 bits (75), Expect = 0.18
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 80 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE---DHTWAPPFPIC 133
C DP V +NG + G D + F C+ Y L+G R C++ + W P P+C
Sbjct: 1488 CRDPGVPMNGTRNGDGR-EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
Score = 33.1 bits (74), Expect = 0.24
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 4/78 (5%)
Query: 20 EHCPELPPVDNSIFVAKEVE-GQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTTECR 76
+ CP+ P N + + GQ + ++ C GY L+G L C S+ W++ C
Sbjct: 2182 QSCPDPRPFRNGFVIGNDFTVGQTI-SFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2240
Query: 77 LGHCPDPVLVNGEFSSSG 94
+ +NG S G
Sbjct: 2241 ALCGGNITAMNGTIYSPG 2258
Score = 30.0 bits (66), Expect = 2.0
Identities = 10/37 (27%), Positives = 18/37 (48%)
Query: 97 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
++ ++F C+ Y L C ++H W+ P P C
Sbjct: 987 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
Score = 29.6 bits (65), Expect = 2.6
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 22 CPELPPVDNSIFVAKEVEGQI--LGTYVCIKGYHLVGKKTLFCNASK--EWDNTTTECRL 77
C PPV N+ + ++ E +I + Y C+ G+ LVG L C + + D C++
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
Query: 78 GHCP 81
CP
Sbjct: 2415 -LCP 2417
Score = 28.9 bits (63), Expect = 4.4
Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 10/111 (9%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG-----HCPDPVLVNGEFSSSGPVNVSD 100
+ C G+ L+G+K++ C + +W C P +++ ++ N++
Sbjct: 648 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 707
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG 151
T + + GS D F +D D P +P+ G F G
Sbjct: 708 IWTIISD-----PGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTG 753
Score = 27.7 bits (60), Expect = 9.9
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 136 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
R C PP + E + F +G I Y C + LVG C GE A PVC
Sbjct: 2353 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2412
Query: 191 KLI 193
+++
Sbjct: 2413 QVL 2415
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 103 bits (257), Expect = 1e-22
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
C ELP N + + + C G+ LVG C +S W + T C GHC
Sbjct: 2590 CGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCG 2649
Query: 82 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P ++VNG+ D + + CN + L GS+ C +DH W+ P C C
Sbjct: 2650 IPELIVNGQVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGH 2708
Query: 141 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
PG+P++G GN F +++ C Y + G + QC + +WS P+CK++
Sbjct: 2709 PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2762
Score = 95.9 bits (237), Expect = 3e-20
Identities = 54/173 (31%), Positives = 78/173 (45%), Gaps = 20/173 (11%)
Query: 38 VEGQILG---------TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVL 85
V GQ++G Y C G+ L+G C W C GH P+
Sbjct: 2655 VNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY 2714
Query: 86 VNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPV 145
G S +G N +D +TF CN Y+++G ++QC + W+ P P+CK +C PG P
Sbjct: 2715 --GRTSGNG-FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2771
Query: 146 H----GYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
+ E NFT G+ + Y C Y+L G C +G+W LP C +I
Sbjct: 2772 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI 2824
Score = 91.7 bits (226), Expect = 6e-19
Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 104
Y C GY L G + C A+ W EC+ C +P NG+ S + +
Sbjct: 2911 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 2970
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
C + YIL G + QC + TW+ P C C PG P +G G+++ +G +SY C
Sbjct: 2971 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3030
Query: 165 EDRY--YLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 206
+ Y L G + + C ++G WS +P C+ + P+ L
Sbjct: 3031 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3075
Score = 86.7 bits (213), Expect = 2e-17
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSS---GPVNVSD 100
T+ C GY + G C A+++W + C++ +C DP + N + S G
Sbjct: 2729 TFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGT 2788
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 160
+ + CN Y L GS+ C + W P P C DC PG P + G +T GST+
Sbjct: 2789 VVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTV 2848
Query: 161 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Y C + L+G + C ++G WS + P C
Sbjct: 2849 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 2879
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Y C GY L G L C + +WD EC + C P + S + +
Sbjct: 2792 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYS 2851
Query: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICK---SRDCDPPGNPVHGYFEGNNFTLGSTISY 162
C L G + C + W+ P C + C PG P HG + +NF ST+ Y
Sbjct: 2852 CTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRY 2911
Query: 163 YCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 194
C+ Y L G +E+ C+ +G W+ P CK +Q
Sbjct: 2912 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQ 2944
Score = 78.6 bits (192), Expect = 5e-15
Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 7/175 (4%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
CP P + N + +Y+C GY L L C + W +C C
Sbjct: 3064 CPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3123
Query: 82 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRD 137
DP + G+ + S+ ++F CN +IL GS+ C D TW+ P C
Sbjct: 3124 DPGIPAQGKREGKSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTS 3182
Query: 138 CDPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
C+ PG P HG F +GS + ++C+ + L G + C+ D WS P C
Sbjct: 3183 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3237
Score = 78.2 bits (191), Expect = 6e-15
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 7/176 (3%)
Query: 23 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR---LGH 79
P +PP N++ ++ Y C L+G+ + C + W + C G
Sbjct: 2829 PGVPP--NAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 2886
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 139
C DP + + C+ YIL GS CL + +W P CK+ C
Sbjct: 2887 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCG 2946
Query: 140 PPGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
PG +G F + T S++ Y C + Y L G +QC +G WS LP C +I
Sbjct: 2947 NPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTII 3002
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 45 TYVCIKGY--HLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 102
+Y+C GY L G + C + W CR CP P ++ + I
Sbjct: 3027 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSI 3086
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
+++C+ Y L C+ + TW+ P C + C PG P G EG +F S +S+
Sbjct: 3087 SYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSF 3146
Query: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKN 213
C + LVG + C DG WS + P C E + CE + S+N
Sbjct: 3147 SCNFPFILVGSSTRICQADGTWSGSSPHC---IEPTQTSCENPGVPRHGSQN 3195
Score = 73.2 bits (178), Expect = 2e-13
Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDP-VLVNGEFSSSGPVNVSD 100
++ C + LVG T C A W ++ C C +P V +G +++ V
Sbjct: 3145 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3204
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 159
+ F C ++L+GS CL D TW+ P C C P P H G + + G T
Sbjct: 3205 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYT 3264
Query: 160 ISYYCEDRYYLVGVQEQQCV--DGEWSSALPVC----KLIQEAPKP 199
+ Y C+ ++L G E + D W+ +P+C K++ + P+P
Sbjct: 3265 LIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3310
Score = 63.9 bits (154), Expect = 1e-10
Identities = 49/179 (27%), Positives = 73/179 (40%), Gaps = 14/179 (7%)
Query: 23 PELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLFCNASK----EWDNTTTECR 76
PE PP ++ + GQ+ + C +G+ LVGK + C S WD C+
Sbjct: 2468 PESPPHG---YIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
Query: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL--KGSNRSQCLEDHTWAP--PFPI 132
C P + V ++T+ CND Y L K + C D TW+ P
Sbjct: 2525 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2584
Query: 133 CKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
C C P +G G + GST + C+ + LVG ++C+ G WS + C
Sbjct: 2585 CVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643
Score = 50.4 bits (119), Expect = 1e-06
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 11/109 (10%)
Query: 102 ITFMCNDHYILKGSNRSQCLED----HTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLG 157
+ + C+ + L G + + C + H W P P C++ C P P +G ++ +G
Sbjct: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVG 2547
Query: 158 STISYYCEDRYYLVGVQEQQCV---DGEWS--SALPVCKLIQ--EAPKP 199
+ ++Y+C D Y L + V DG WS + P C +I E P P
Sbjct: 2548 TRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTP 2596
Score = 48.9 bits (115), Expect = 4e-06
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WSSALPVC 190
C PGN ++G G ++ LGST++YYC+ Y L G C+ G+ W+ ALP C
Sbjct: 1597 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
Score = 48.5 bits (114), Expect = 5e-06
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKL 192
C PG P +G G++F+LGST+ + C++ Y L G + C V WS PVCK+
Sbjct: 382 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 441
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-WSSALPVC 190
C PG PVHG G++F++GST+S+ C+ Y L + C WS LP C
Sbjct: 906 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
Score = 45.1 bits (105), Expect = 6e-05
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C+ PG P +G G NF +G T+++ C Y L G E C+ G WS+ LP C
Sbjct: 1078 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
Score = 42.7 bits (99), Expect = 3e-04
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 136 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVCKL 192
+ C P +G+ GN+FT+G TIS+ C Y L+G C+ G W+ LP C+
Sbjct: 2118 QSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2177
Query: 193 I 193
+
Sbjct: 2178 L 2178
Score = 42.0 bits (97), Expect = 5e-04
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 190
+ C PG P++G EG+ F+ + + C+ + L+G + C + +WS+ +P+C
Sbjct: 556 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
Score = 41.2 bits (95), Expect = 9e-04
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 137 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVC 190
+C PG P++ G+NF LGS+IS CE+ + G + C+ DG+ WS +P C
Sbjct: 729 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWSSALP 188
+S C PG P G G F +G I Y C Y L G + C+ W +P
Sbjct: 174 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
Query: 189 VCK 191
+C+
Sbjct: 234 ICR 236
Score = 37.4 bits (85), Expect = 0.012
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 138 CDPPGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
C+ PG P GY GSTI Y C Y L G +C+ GE W LP C
Sbjct: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1306
Score = 37.0 bits (84), Expect = 0.016
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 190
C PG P++G G+ G T+ + C+ Y L G + C+ E W + PVC
Sbjct: 1424 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
Score = 36.6 bits (83), Expect = 0.021
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
Query: 71 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 128
T +E L C DP + + D +TF C+ Y L+G++ CL W+
Sbjct: 1069 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1128
Query: 129 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
P P C + +C G N+ L ++ C
Sbjct: 1129 PLPRCVA-ECGASATNNEGILLSPNYPLNYENNHEC 1163
Score = 35.8 bits (81), Expect = 0.036
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 2/63 (3%)
Query: 73 TECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPF 130
T L CP+P + V D ++F C+ Y L+G + C+ W P
Sbjct: 1941 TAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPI 2000
Query: 131 PIC 133
PIC
Sbjct: 2001 PIC 2003
Score = 35.0 bits (79), Expect = 0.062
Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE----DHTWAPPFPICKS 135
CPDP ++ + F C++ Y+L+G+ C W+ P+CK
Sbjct: 382 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 441
Query: 136 RDCDPPGNPVHGYFEGNNF 154
+ C G F NF
Sbjct: 442 KTCGSNLQGPSGTFTSPNF 460
Score = 34.7 bits (78), Expect = 0.081
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 131 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSS 185
P S C P G GN F +GS++ + C Y L G +C +W+
Sbjct: 1767 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1826
Query: 186 ALPVC 190
+LP C
Sbjct: 1827 SLPTC 1831
Score = 34.3 bits (77), Expect = 0.11
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 76 RLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 133
+L CPDP F V I+F C Y L G++ CL W P P C
Sbjct: 2116 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2175
Query: 134 KS 135
++
Sbjct: 2176 EA 2177
Score = 33.9 bits (76), Expect = 0.14
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 73 TECRLGHCPDPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRSQCL--EDHTWAPP 129
T L HC DP + + S + + I + CN Y L GS+ +C+ E W P
Sbjct: 1243 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYP 1302
Query: 130 FPIC 133
P C
Sbjct: 1303 LPSC 1306
Score = 33.5 bits (75), Expect = 0.18
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 97 NVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFPICKSRD 137
+V DKI + C YIL G + C+ + +W P PIC++ D
Sbjct: 195 DVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Score = 33.5 bits (75), Expect = 0.18
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 80 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE---DHTWAPPFPIC 133
C DP V +NG + G D + F C+ Y L+G R C++ + W P P+C
Sbjct: 1424 CRDPGVPMNGTRNGDGR-EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
Score = 33.1 bits (74), Expect = 0.24
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 4/78 (5%)
Query: 20 EHCPELPPVDNSIFVAKEVE-GQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTTECR 76
+ CP+ P N + + GQ + ++ C GY L+G L C S+ W++ C
Sbjct: 2118 QSCPDPRPFRNGFVIGNDFTVGQTI-SFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
Query: 77 LGHCPDPVLVNGEFSSSG 94
+ +NG S G
Sbjct: 2177 ALCGGNITAMNGTIYSPG 2194
Score = 30.0 bits (66), Expect = 2.0
Identities = 10/37 (27%), Positives = 18/37 (48%)
Query: 97 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
++ ++F C+ Y L C ++H W+ P P C
Sbjct: 923 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
Score = 29.6 bits (65), Expect = 2.6
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 22 CPELPPVDNSIFVAKEVEGQI--LGTYVCIKGYHLVGKKTLFCNASK--EWDNTTTECRL 77
C PPV N+ + ++ E +I + Y C+ G+ LVG L C + + D C++
Sbjct: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
Query: 78 GHCP 81
CP
Sbjct: 2351 -LCP 2353
Score = 28.9 bits (63), Expect = 4.4
Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 10/111 (9%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG-----HCPDPVLVNGEFSSSGPVNVSD 100
+ C G+ L+G+K++ C + +W C P +++ ++ N++
Sbjct: 584 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG 151
T + + GS D F +D D P +P+ G F G
Sbjct: 644 IWTIISD-----PGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTG 689
Score = 27.7 bits (60), Expect = 9.9
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 136 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
R C PP + E + F +G I Y C + LVG C GE A PVC
Sbjct: 2289 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2348
Query: 191 KLI 193
+++
Sbjct: 2349 QVL 2351
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 103 bits (257), Expect = 1e-22
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
C ELP N + + + C G+ LVG C +S W + T C GHC
Sbjct: 2759 CGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCG 2818
Query: 82 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P ++VNG+ D + + CN + L GS+ C +DH W+ P C C
Sbjct: 2819 IPELIVNGQVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGH 2877
Query: 141 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
PG+P++G GN F +++ C Y + G + QC + +WS P+CK++
Sbjct: 2878 PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2931
Score = 95.9 bits (237), Expect = 3e-20
Identities = 54/173 (31%), Positives = 78/173 (45%), Gaps = 20/173 (11%)
Query: 38 VEGQILG---------TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVL 85
V GQ++G Y C G+ L+G C W C GH P+
Sbjct: 2824 VNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY 2883
Query: 86 VNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPV 145
G S +G N +D +TF CN Y+++G ++QC + W+ P P+CK +C PG P
Sbjct: 2884 --GRTSGNG-FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2940
Query: 146 H----GYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
+ E NFT G+ + Y C Y+L G C +G+W LP C +I
Sbjct: 2941 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI 2993
Score = 91.7 bits (226), Expect = 6e-19
Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 104
Y C GY L G + C A+ W EC+ C +P NG+ S + +
Sbjct: 3080 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 3139
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
C + YIL G + QC + TW+ P C C PG P +G G+++ +G +SY C
Sbjct: 3140 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3199
Query: 165 EDRY--YLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 206
+ Y L G + + C ++G WS +P C+ + P+ L
Sbjct: 3200 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3244
Score = 86.7 bits (213), Expect = 2e-17
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSS---GPVNVSD 100
T+ C GY + G C A+++W + C++ +C DP + N + S G
Sbjct: 2898 TFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGT 2957
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 160
+ + CN Y L GS+ C + W P P C DC PG P + G +T GST+
Sbjct: 2958 VVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTV 3017
Query: 161 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Y C + L+G + C ++G WS + P C
Sbjct: 3018 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3048
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Y C GY L G L C + +WD EC + C P + S + +
Sbjct: 2961 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYS 3020
Query: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICK---SRDCDPPGNPVHGYFEGNNFTLGSTISY 162
C L G + C + W+ P C + C PG P HG + +NF ST+ Y
Sbjct: 3021 CTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRY 3080
Query: 163 YCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 194
C+ Y L G +E+ C+ +G W+ P CK +Q
Sbjct: 3081 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQ 3113
Score = 78.6 bits (192), Expect = 5e-15
Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 7/175 (4%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
CP P + N + +Y+C GY L L C + W +C C
Sbjct: 3233 CPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3292
Query: 82 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRD 137
DP + G+ + S+ ++F CN +IL GS+ C D TW+ P C
Sbjct: 3293 DPGIPAQGKREGKSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTS 3351
Query: 138 CDPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
C+ PG P HG F +GS + ++C+ + L G + C+ D WS P C
Sbjct: 3352 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3406
Score = 78.2 bits (191), Expect = 6e-15
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 7/176 (3%)
Query: 23 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR---LGH 79
P +PP N++ ++ Y C L+G+ + C + W + C G
Sbjct: 2998 PGVPP--NAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 3055
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 139
C DP + + C+ YIL GS CL + +W P CK+ C
Sbjct: 3056 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCG 3115
Query: 140 PPGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
PG +G F + T S++ Y C + Y L G +QC +G WS LP C +I
Sbjct: 3116 NPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTII 3171
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 45 TYVCIKGY--HLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 102
+Y+C GY L G + C + W CR CP P ++ + I
Sbjct: 3196 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSI 3255
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
+++C+ Y L C+ + TW+ P C + C PG P G EG +F S +S+
Sbjct: 3256 SYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSF 3315
Query: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKN 213
C + LVG + C DG WS + P C E + CE + S+N
Sbjct: 3316 SCNFPFILVGSSTRICQADGTWSGSSPHC---IEPTQTSCENPGVPRHGSQN 3364
Score = 73.2 bits (178), Expect = 2e-13
Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDP-VLVNGEFSSSGPVNVSD 100
++ C + LVG T C A W ++ C C +P V +G +++ V
Sbjct: 3314 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3373
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 159
+ F C ++L+GS CL D TW+ P C C P P H G + + G T
Sbjct: 3374 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYT 3433
Query: 160 ISYYCEDRYYLVGVQEQQCV--DGEWSSALPVC----KLIQEAPKP 199
+ Y C+ ++L G E + D W+ +P+C K++ + P+P
Sbjct: 3434 LIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3479
Score = 57.8 bits (138), Expect = 9e-09
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 12/158 (7%)
Query: 45 TYVCIKGYHLVGKK--TLFCNASKEWDN--TTTECRLGHCPDP---VLVNGEFS--SSGP 95
TY C GY L K+ T C + W N T C + CP +L +G + +
Sbjct: 2655 TYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH 2714
Query: 96 VNVSDKITFMCNDHYILKGSNRSQCLEDHTWA--PPFPICKSRDCDPPGNPVHGYFEGNN 153
K+ F C+ Y G +CL + TW+ P C+ C P +G G
Sbjct: 2715 YEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQ 2774
Query: 154 FTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
+ GST + C+ + LVG ++C+ G WS + C
Sbjct: 2775 TSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2812
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 23/197 (11%)
Query: 23 PELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLFCNASK----EWDNTTTECR 76
PE PP ++ + GQ+ + C +G+ LVGK + C S WD C+
Sbjct: 2572 PESPPHG---YIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Query: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL--KGSNRSQCLEDHTWA--PPFPI 132
C P + V ++T+ CND Y L K + C D TW+ P
Sbjct: 2629 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2688
Query: 133 CKSRDCDPPGNPV--HGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWS-- 184
C C + + HG + G+++ + + + C+ Y+ +G +C+ +G WS
Sbjct: 2689 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2748
Query: 185 SALPVCKLIQ--EAPKP 199
+ P C++I E P P
Sbjct: 2749 NERPYCQIISCGELPTP 2765
Score = 48.9 bits (115), Expect = 4e-06
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WSSALPVC 190
C PGN ++G G ++ LGST++YYC+ Y L G C+ G+ W+ ALP C
Sbjct: 1701 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1758
Score = 48.5 bits (114), Expect = 5e-06
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKL 192
C PG P +G G++F+LGST+ + C++ Y L G + C V WS PVCK+
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-WSSALPVC 190
C PG PVHG G++F++GST+S+ C+ Y L + C WS LP C
Sbjct: 1010 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1063
Score = 45.1 bits (105), Expect = 6e-05
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C+ PG P +G G NF +G T+++ C Y L G E C+ G WS+ LP C
Sbjct: 1182 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1237
Score = 42.7 bits (99), Expect = 3e-04
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 136 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVCKL 192
+ C P +G+ GN+FT+G TIS+ C Y L+G C+ G W+ LP C+
Sbjct: 2222 QSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2281
Query: 193 I 193
+
Sbjct: 2282 L 2282
Score = 42.0 bits (97), Expect = 5e-04
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 190
+ C PG P++G EG+ F+ + + C+ + L+G + C + +WS+ +P+C
Sbjct: 660 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 717
Score = 41.2 bits (95), Expect = 9e-04
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 137 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVC 190
+C PG P++ G+NF LGS+IS CE+ + G + C+ DG+ WS +P C
Sbjct: 833 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 891
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWSSALP 188
+S C PG P G G F +G I Y C Y L G + C+ W +P
Sbjct: 174 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
Query: 189 VCK 191
+C+
Sbjct: 234 ICR 236
Score = 37.4 bits (85), Expect = 0.012
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 138 CDPPGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
C+ PG P GY GSTI Y C Y L G +C+ GE W LP C
Sbjct: 1354 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1410
Score = 37.0 bits (84), Expect = 0.016
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 190
C PG P++G G+ G T+ + C+ Y L G + C+ E W + PVC
Sbjct: 1528 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
Score = 36.6 bits (83), Expect = 0.021
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
Query: 71 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 128
T +E L C DP + + D +TF C+ Y L+G++ CL W+
Sbjct: 1173 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1232
Query: 129 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
P P C + +C G N+ L ++ C
Sbjct: 1233 PLPRCVA-ECGASATNNEGILLSPNYPLNYENNHEC 1267
Score = 35.8 bits (81), Expect = 0.036
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 2/63 (3%)
Query: 73 TECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPF 130
T L CP+P + V D ++F C+ Y L+G + C+ W P
Sbjct: 2045 TAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPI 2104
Query: 131 PIC 133
PIC
Sbjct: 2105 PIC 2107
Score = 35.0 bits (79), Expect = 0.062
Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE----DHTWAPPFPICKS 135
CPDP ++ + F C++ Y+L+G+ C W+ P+CK
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Query: 136 RDCDPPGNPVHGYFEGNNF 154
+ C G F NF
Sbjct: 546 KTCGSNLQGPSGTFTSPNF 564
Score = 34.7 bits (78), Expect = 0.081
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 131 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSS 185
P S C P G GN F +GS++ + C Y L G +C +W+
Sbjct: 1871 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1930
Query: 186 ALPVC 190
+LP C
Sbjct: 1931 SLPTC 1935
Score = 34.3 bits (77), Expect = 0.11
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 76 RLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 133
+L CPDP F V I+F C Y L G++ CL W P P C
Sbjct: 2220 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2279
Query: 134 KS 135
++
Sbjct: 2280 EA 2281
Score = 33.9 bits (76), Expect = 0.14
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 73 TECRLGHCPDPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRSQCL--EDHTWAPP 129
T L HC DP + + S + + I + CN Y L GS+ +C+ E W P
Sbjct: 1347 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYP 1406
Query: 130 FPIC 133
P C
Sbjct: 1407 LPSC 1410
Score = 33.5 bits (75), Expect = 0.18
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 97 NVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFPICKSRD 137
+V DKI + C YIL G + C+ + +W P PIC++ D
Sbjct: 195 DVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Score = 33.5 bits (75), Expect = 0.18
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 80 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE---DHTWAPPFPIC 133
C DP V +NG + G D + F C+ Y L+G R C++ + W P P+C
Sbjct: 1528 CRDPGVPMNGTRNGDGR-EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
Score = 33.1 bits (74), Expect = 0.24
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 4/78 (5%)
Query: 20 EHCPELPPVDNSIFVAKEVE-GQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTTECR 76
+ CP+ P N + + GQ + ++ C GY L+G L C S+ W++ C
Sbjct: 2222 QSCPDPRPFRNGFVIGNDFTVGQTI-SFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2280
Query: 77 LGHCPDPVLVNGEFSSSG 94
+ +NG S G
Sbjct: 2281 ALCGGNITAMNGTIYSPG 2298
Score = 30.0 bits (66), Expect = 2.0
Identities = 10/37 (27%), Positives = 18/37 (48%)
Query: 97 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
++ ++F C+ Y L C ++H W+ P P C
Sbjct: 1027 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1063
Score = 29.6 bits (65), Expect = 2.6
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 22 CPELPPVDNSIFVAKEVEGQI--LGTYVCIKGYHLVGKKTLFCNASK--EWDNTTTECRL 77
C PPV N+ + ++ E +I + Y C+ G+ LVG L C + + D C++
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2454
Query: 78 GHCP 81
CP
Sbjct: 2455 -LCP 2457
Score = 28.9 bits (63), Expect = 4.4
Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 10/111 (9%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG-----HCPDPVLVNGEFSSSGPVNVSD 100
+ C G+ L+G+K++ C + +W C P +++ ++ N++
Sbjct: 688 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 747
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG 151
T + + GS D F +D D P +P+ G F G
Sbjct: 748 IWTIISD-----PGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTG 793
Score = 27.7 bits (60), Expect = 9.9
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 136 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
R C PP + E + F +G I Y C + LVG C GE A PVC
Sbjct: 2393 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2452
Query: 191 KLI 193
+++
Sbjct: 2453 QVL 2455
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 99.8 bits (247), Expect = 2e-21
Identities = 53/172 (30%), Positives = 80/172 (46%), Gaps = 5/172 (2%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC- 80
C ELP N + + C GY LVG + C A+ W + C GHC
Sbjct: 2658 CGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCG 2717
Query: 81 -PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 139
P+P+ VNG + + + + CN + L G + C +DH W+ P C C
Sbjct: 2718 TPEPI-VNGHINGEN-YSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCG 2775
Query: 140 PPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
PG+P H G+++T+G+ + Y C + LVG + C +DG W+ +LP C
Sbjct: 2776 HPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC 2827
Score = 78.2 bits (191), Expect = 6e-15
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Y C +GY+ G + C+ + W + EC + +C DP + + +T+
Sbjct: 2918 YECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQ 2977
Query: 106 CNDHYILKGSNRS--QCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 163
C Y+++ S C +D TW P+CK+ C PP +G G++F GS+++Y
Sbjct: 2978 CVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYA 3037
Query: 164 CEDRYYLVGVQEQQCV-DGEWSSALPVC 190
C + Y L C +G W+ LP C
Sbjct: 3038 CLEGYQLSLPAVFTCEGNGSWTGELPQC 3065
Score = 76.3 bits (186), Expect = 2e-14
Identities = 47/177 (26%), Positives = 66/177 (37%), Gaps = 4/177 (2%)
Query: 21 HCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC 80
HC P+ N + + Y C G+ L+G C W T C L C
Sbjct: 2715 HCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSC 2774
Query: 81 PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--- 137
P S V + + C L G++ C D W P C
Sbjct: 2775 GHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGV 2834
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
C PG P HG G++F G+ + + CE + L G E+ C +G WS + P C +I
Sbjct: 2835 CGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVI 2891
Score = 74.7 bits (182), Expect = 7e-14
Identities = 45/162 (27%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVN-GEFSSSGPVNVSD 100
++ C LVG FC + W T C L C DP + G ++S V
Sbjct: 3093 SFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGS 3152
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 159
+ F C Y+L+GS CL + TW+ P C C P P H + ++G T
Sbjct: 3153 TVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYT 3212
Query: 160 ISYYCEDRYYLVGVQEQQC--VDGEWSSALPVCKLIQEAPKP 199
+ Y C++ + L G E + DG W+ P+C ++ + +P
Sbjct: 3213 LIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRP 3254
Score = 73.6 bits (179), Expect = 2e-13
Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 4/158 (2%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 104
+ C G+ L G C A+ W + EC + C +P N S + S I +
Sbjct: 2859 FSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVY 2918
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
C + Y G C + TW P C +C PG P +G GN+F T++Y C
Sbjct: 2919 ECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQC 2978
Query: 165 EDRYYLVG--VQEQQCV-DGEWSSALPVCKLIQEAPKP 199
Y + V C D W+ PVCK + P P
Sbjct: 2979 VPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPP 3016
Score = 70.1 bits (170), Expect = 2e-12
Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 5/150 (3%)
Query: 45 TYVCIKGYHLVGKKT--LFCNASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVNVSDK 101
TY C+ GY + + L C + W+ T C+ C P P++ NG+ S + S
Sbjct: 2975 TYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSS- 3033
Query: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTIS 161
+T+ C + Y L C + +W P C C PG P G E F+ S++S
Sbjct: 3034 VTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVS 3093
Query: 162 YYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
+ C LVG + C DG WS P C
Sbjct: 3094 FSCHPPLVLVGSPRRFCQSDGTWSGTQPSC 3123
Score = 70.1 bits (170), Expect = 2e-12
Identities = 45/174 (25%), Positives = 67/174 (38%), Gaps = 5/174 (2%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
C P + N V + TY C++GY L C + W +C C
Sbjct: 3012 CKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 3071
Query: 82 DPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRDC 138
DP + + + ++F C+ +L GS R C D TW+ P C C
Sbjct: 3072 DPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTC 3131
Query: 139 DPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 190
PG P G + + +GST+ + C+ Y L G + C+ WS P C
Sbjct: 3132 ADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
Score = 52.4 bits (124), Expect = 4e-07
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Query: 75 CRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPF 130
C L P + G+ S+ I F CN Y L G + + C H W+
Sbjct: 2468 CSLPRAPLHGFILGQTSTQP----GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAI 2523
Query: 131 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQE--QQCVD-GEWSS 185
P+C++ C P P +G G +T+G+ Y C + Y+L E +C+D G WS+
Sbjct: 2524 PLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSN 2581
Score = 51.2 bits (121), Expect = 8e-07
Identities = 44/180 (24%), Positives = 69/180 (38%), Gaps = 14/180 (7%)
Query: 23 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVG--KKTLFCNASKEWDNTTT--ECRLG 78
PE P N + KE Y C +GYHL + T C + W N +C
Sbjct: 2534 PEAPK--NGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPV 2591
Query: 79 HCPDPVLVNGEFSS-----SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWA--PPFP 131
CPD ++ E ++ +C+ Y G +C + W+ P
Sbjct: 2592 TCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTP 2651
Query: 132 ICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
C+ C P +G+ G G+T + C Y LVG + ++C+ +G WS + C
Sbjct: 2652 TCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRC 2711
Score = 45.4 bits (106), Expect = 5e-05
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKL 192
+S C PG PV+G GN+F +G+ +++ C+ Y L + +C +WS ALP C+
Sbjct: 863 QSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA 922
Query: 193 I 193
+
Sbjct: 923 L 923
Score = 43.9 bits (102), Expect = 1e-04
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 78 GH--CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFP 131
GH CPDP + + + F CN+ Y L+GS R C++ W+ P
Sbjct: 339 GHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
Query: 132 ICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
+C++R CD G NF + + +C
Sbjct: 399 VCRARMCDAHLRGPSGIITSPNFPIQYDNNAHC 431
Score = 42.7 bits (99), Expect = 3e-04
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
Query: 110 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGY-FEGNNFTLGSTISYYCEDRY 168
+I N S+ E H + F + K C+ PG P GY GS++S+ C+ Y
Sbjct: 1188 FITDAENTSKGFELHFSS--FELIK---CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGY 1242
Query: 169 YLVGVQEQQCVDGE---WSSALPVC 190
L G +E C+ GE W LP C
Sbjct: 1243 SLRGSEELLCLSGERRTWDRPLPTC 1267
Score = 41.6 bits (96), Expect = 7e-04
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
C PG P +G EG+ F G T+ + C+ + LVG + C + +WS+ P C
Sbjct: 521 CGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
Score = 41.2 bits (95), Expect = 9e-04
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV---DGE--WSSALPVC 190
C PG+ +G G++ LGS+++YYC Y + G C+ DG+ W++ PVC
Sbjct: 1558 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC 1615
Score = 40.4 bits (93), Expect = 0.001
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSSALPVCK 191
C PG P G G++F LGS++ + C + Y L G + C+ WS PVC+
Sbjct: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCR 401
Score = 38.5 bits (88), Expect = 0.006
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 126 WAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE--- 182
+A F + + C+ PG P +G G+++ G + + C+ Y L G E CV E
Sbjct: 1373 FAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRF 1432
Query: 183 -WSSALPVC 190
W + P C
Sbjct: 1433 FWQPSPPTC 1441
Score = 37.4 bits (85), Expect = 0.012
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
Query: 130 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYY-LVGVQEQQCVDGE----WS 184
F + +C PG PV+G G++ LGS+IS+ C++ + G + CV E W+
Sbjct: 683 FTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWN 742
Query: 185 SALPVCK 191
SA+ C+
Sbjct: 743 SAVLRCE 749
Score = 37.0 bits (84), Expect = 0.016
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
Query: 130 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WS 184
+ + S C PG +G +G+ F LG + Y C ++L G C G W
Sbjct: 131 YEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
Query: 185 SALPVCK 191
LP C+
Sbjct: 191 FPLPSCR 197
Score = 35.8 bits (81), Expect = 0.036
Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 21/110 (19%)
Query: 63 NASKEWDNTTTECRLGHCPDP--------VLVNGEFSSSGPVNVSDKITFMCNDHYILKG 114
N SK ++ + L C DP V G F+ S ++F C+ Y L+G
Sbjct: 1194 NTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSS-------VSFSCDPGYSLRG 1246
Query: 115 SNRSQCL--EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
S CL E TW P P C + +C G V G G + G Y
Sbjct: 1247 SEELLCLSGERRTWDRPLPTCVA-EC---GGTVRGEVSGQVLSPGYPAPY 1292
Score = 35.4 bits (80), Expect = 0.047
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 3/96 (3%)
Query: 71 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL--EDHTWAP 128
T +E L C +P + V D +TF C Y L+G+ R CL W+
Sbjct: 1030 TFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSS 1089
Query: 129 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
P P C + +C G NF + ++ C
Sbjct: 1090 PLPRCVA-ECGNSVTGTQGTLLSPNFPVNYNNNHEC 1124
Score = 34.3 bits (77), Expect = 0.11
Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 2/59 (3%)
Query: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPFPIC 133
L CP+P + + + V+D ++F C Y L+G C+ W P P+C
Sbjct: 1906 LSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC 1964
Score = 33.1 bits (74), Expect = 0.24
Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 2/77 (2%)
Query: 20 EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTTECRL 77
+ CP+ P N I T+ C+ GY L G L C ++ WD+ +C +
Sbjct: 2121 QECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEV 2180
Query: 78 GHCPDPVLVNGEFSSSG 94
+ NG S G
Sbjct: 2181 PCGGNITSSNGTVYSPG 2197
Score = 32.3 bits (72), Expect = 0.40
Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 79 HCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 135
HC DP + VNG+ V +TF C+ Y L +C + W+ P C++
Sbjct: 866 HCLDPGIPVNGQ-RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA 922
Score = 30.8 bits (68), Expect = 1.2
Identities = 16/62 (25%), Positives = 25/62 (40%), Gaps = 4/62 (6%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC----LEDHTWAPPFPICKS 135
C +P + N+ DK+ + CN + L+G C TW P P C++
Sbjct: 139 CGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
Query: 136 RD 137
D
Sbjct: 199 DD 200
Score = 30.4 bits (67), Expect = 1.5
Identities = 16/57 (28%), Positives = 21/57 (36%), Gaps = 3/57 (5%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT---WAPPFPIC 133
C DP + S D F C+ Y L+GS C++ W P P C
Sbjct: 1385 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
Score = 27.7 bits (60), Expect = 9.9
Identities = 22/109 (20%), Positives = 40/109 (36%), Gaps = 8/109 (7%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL----EDHTWAPPFPICKS 135
C DP + + + +T+ C+ Y ++G++ C+ W P P+C +
Sbjct: 1558 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC-T 1616
Query: 136 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWS 184
C G N+ T C Y V V + V G+++
Sbjct: 1617 APCGGQYVGSDGVVLSPNYPQNYTSGQIC---LYFVTVPKDYVVFGQFA 1662
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 96.7 bits (239), Expect = 2e-20
Identities = 55/182 (30%), Positives = 82/182 (45%), Gaps = 4/182 (2%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT-ECRLGHC 80
C + PP+ N + E + C +GY LVG + C S +W+ + +C C
Sbjct: 2264 CGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKC 2323
Query: 81 PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P+P L+ + +TF C + ++L+G + +CL W FP+CK C P
Sbjct: 2324 PEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTP 2383
Query: 141 PGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPK 198
P G + GST+ Y C ++L G C DG WSS LP C + E P+
Sbjct: 2384 PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV-ECPQ 2442
Query: 199 PE 200
PE
Sbjct: 2443 PE 2444
Score = 94.7 bits (234), Expect = 7e-20
Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 2/170 (1%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
CP+ + N I + + Y C G+ LVG T C + W C+ C
Sbjct: 2440 CPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECL 2499
Query: 82 DPV-LVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P ++NG+FS + ++ +T+ CN + L+G + CLE W P C + CD
Sbjct: 2500 KPKEILNGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDS 2558
Query: 141 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVC 190
P +G+ EG +++ G+ I Y C + + G Q C + WSS++P C
Sbjct: 2559 PQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTC 2608
Score = 93.2 bits (230), Expect = 2e-19
Identities = 55/182 (30%), Positives = 80/182 (43%), Gaps = 11/182 (6%)
Query: 19 DEHCPELPPVDNSIFVAKEVEGQILGT---------YVCIKGYHLVGKKTLFCNASKEWD 69
DE P PVD S GQ+ G Y C +G+ L G ++ C A+ W
Sbjct: 2822 DEDEPICIPVDCSS-PPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWS 2880
Query: 70 NTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPP 129
T +C C P + + ++TF C++ YIL G+ + C D W
Sbjct: 2881 GATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAE 2940
Query: 130 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALP 188
P+CK +C PP + HG+ G +F G I Y C Y L G ++C+ +G WS + P
Sbjct: 2941 IPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSP 3000
Query: 189 VC 190
C
Sbjct: 3001 SC 3002
Score = 91.3 bits (225), Expect = 7e-19
Identities = 58/215 (26%), Positives = 88/215 (40%), Gaps = 42/215 (19%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT------EC 75
C PP++N A + TY C GY+L+G +FC + W+ + EC
Sbjct: 1690 CGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDEC 1749
Query: 76 RLG-----------------------------HCPDPVLVNGEFS-----SSGPV-NVSD 100
+G +C +P+ + SSG + V
Sbjct: 1750 AVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGA 1809
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 160
++TF C + Y L G + CLE W P CK+ C P P +G E FT GS +
Sbjct: 1810 EVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKV 1869
Query: 161 SYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 194
+Y C Y L G +E C+ + WS + PVC+ ++
Sbjct: 1870 TYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVK 1904
Score = 89.7 bits (221), Expect = 2e-18
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 1/163 (0%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 104
T+ C +GY L+G + C S EW++ C+ C P + K+T+
Sbjct: 1812 TFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTY 1871
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
CN Y L G S CL + +W+ P+C+ C P N +G + + T ST SY C
Sbjct: 1872 RCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSC 1931
Query: 165 EDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 206
+ Y L G +C G W A P C L+ P + A++
Sbjct: 1932 DTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVI 1974
Score = 89.4 bits (220), Expect = 3e-18
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 1/147 (0%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 104
+Y C GY L+G L C W+ + C C P F ++ + +
Sbjct: 2682 SYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQY 2741
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
C +IL GS+ CLE+ W+ P C++ C P ++G +G+N+T ST+ Y C
Sbjct: 2742 SCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYEC 2801
Query: 165 EDRYYLVGVQEQQCVDGE-WSSALPVC 190
+ Y L G + + C D + W P+C
Sbjct: 2802 DPGYVLNGTERRTCQDDKNWDEDEPIC 2828
Score = 88.2 bits (217), Expect = 6e-18
Identities = 53/182 (29%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 22 CPELPPVDNSIFVAKEVEGQI-LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC 80
CPE P ++N + V KE+ ++ + T+ C +G+ L G L C S++W+++ C++ C
Sbjct: 2323 CPEPPLLENQL-VLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLC 2381
Query: 81 PDPVLVN-GEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 139
P L++ G S ++ + + C + L+G++ + C D TW+ P P C +C
Sbjct: 2382 TPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECP 2441
Query: 140 PPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPK 198
P +G + ST Y C+ + LVG C +G W P CK I E K
Sbjct: 2442 QPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI-ECLK 2500
Query: 199 PE 200
P+
Sbjct: 2501 PK 2502
Score = 88.2 bits (217), Expect = 6e-18
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKIT 103
Y C G+ L G C +++W + C C P+PV+ NG S +S +
Sbjct: 2741 YSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVM-NGSIKGSNYTYLST-LY 2798
Query: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 163
+ C+ Y+L G+ R C +D W PIC DC P +G G+ +T I Y
Sbjct: 2799 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYT 2858
Query: 164 CEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKPE 200
C + + L G + + C+ +G WS A P C ++ A P+
Sbjct: 2859 CNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQ 2896
Score = 86.7 bits (213), Expect = 2e-17
Identities = 50/174 (28%), Positives = 75/174 (43%), Gaps = 4/174 (2%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHL-VGKKTLFCNASKEWDNTTTECRLGHC 80
C P V N++ + + C++GY + T C W C C
Sbjct: 3122 CGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKC 3181
Query: 81 PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPF--PICKSRDC 138
P P + +V+ +++ C + Y +G N S C D TW PPF C C
Sbjct: 3182 PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSC 3241
Query: 139 DPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCK 191
P +P HG+ G+ +T STI Y CE Y L G +E+ C + +WS + +CK
Sbjct: 3242 GKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICK 3295
Score = 82.0 bits (201), Expect = 4e-16
Identities = 45/188 (23%), Positives = 74/188 (39%), Gaps = 42/188 (22%)
Query: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCN 107
C G+ LVG +C +W C C P + F S+ +T+ CN
Sbjct: 1658 CDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCN 1717
Query: 108 DHYILKGSNRSQCLEDHTWAPPFPICKSRD------------------------------ 137
+ Y L G +R C ++ +W P C D
Sbjct: 1718 NGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYT 1777
Query: 138 -----------CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSS 185
C PGNP +G+ G +T+G+ +++ C++ Y L+GV + C++ GEW+
Sbjct: 1778 GDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNH 1837
Query: 186 ALPVCKLI 193
+P CK +
Sbjct: 1838 LIPYCKAV 1845
Score = 82.0 bits (201), Expect = 4e-16
Identities = 50/196 (25%), Positives = 81/196 (41%), Gaps = 11/196 (5%)
Query: 37 EVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSS 92
++E + G Y C +GY L G C + W + C+ CP P V+ S
Sbjct: 3311 DIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLS 3370
Query: 93 SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN 152
V ++ C + ++L+G C D TW C+ C PP + + G
Sbjct: 3371 EKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGV 3430
Query: 153 NFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKPECEKALLAFQES 211
++ G I+Y C Y L G C++ G W+S P+C+ + P C+ + +
Sbjct: 3431 HYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICRAVCRFP---CQNGGIC--QR 3484
Query: 212 KNLCEAMENFMQQLKE 227
N C E +M +L E
Sbjct: 3485 PNACSCPEGWMGRLCE 3500
Score = 80.5 bits (197), Expect = 1e-15
Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 7/194 (3%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
C E P + N + Y C KG+++ G+K C A+ +W + C C
Sbjct: 2146 CGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCG 2205
Query: 82 DPVLVNGEF--SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPI-CKSRDC 138
+P V F ++G + S+ + + CN Y GS C + W P+ C DC
Sbjct: 2206 EPPKVENGFLEHTTGRIFESE-VRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDC 2264
Query: 139 DPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWS-SALPVCKLIQEA 196
P +G+ +G NF +GS + ++C + Y LVG C G+W+ + P C + +
Sbjct: 2265 GKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC-MPAKC 2323
Query: 197 PKPECEKALLAFQE 210
P+P + L +E
Sbjct: 2324 PEPPLLENQLVLKE 2337
Score = 79.3 bits (194), Expect = 3e-15
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 3/154 (1%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 104
Y C GY L G + C K WD C C P V NG+ +I +
Sbjct: 2799 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGD-EYTFQKEIEY 2857
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
CN+ ++L+G+ CL + +W+ P C C P +G EG ++ ++++C
Sbjct: 2858 TCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHC 2917
Query: 165 EDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAP 197
+ Y L G + C DG W + +P+CK + P
Sbjct: 2918 HEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 2951
Score = 76.3 bits (186), Expect = 2e-14
Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 1/163 (0%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
C ++N ++ + +Y C GY L G + C AS WD C L C
Sbjct: 1905 CSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCG 1964
Query: 82 DPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP 141
+P + + + +T+ C + Y L G + +CL D W+ C + CD P
Sbjct: 1965 EPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEP 2024
Query: 142 GNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEW 183
H E + G YYC D Y L + C G+W
Sbjct: 2025 PIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKW 2067
Score = 73.6 bits (179), Expect = 2e-13
Identities = 51/184 (27%), Positives = 73/184 (39%), Gaps = 9/184 (4%)
Query: 14 RVSASDEHCPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDN 70
R+S S + CP LP I V + V Q+ + C +GY G C W+
Sbjct: 3173 RISCSPKKCP-LPENITHILVHGDDFSVNRQV--SVSCAEGYTFEGVNISVCQLDGTWEP 3229
Query: 71 TTTE--CRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAP 128
++ C C P F I + C Y L+G+ C E+ W+
Sbjct: 3230 PFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSG 3289
Query: 129 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSAL 187
ICK C+ P ++G + N T G + Y C Y L G E C + G WS +
Sbjct: 3290 GVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPV 3349
Query: 188 PVCK 191
P+CK
Sbjct: 3350 PLCK 3353
Score = 70.9 bits (172), Expect = 1e-12
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
C E P + +++ + TY C +GY L G T+ C A +W + +C C
Sbjct: 1963 CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 2022
Query: 82 DPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPP----FPICKSRD 137
+P +V+ + D + C+D Y L +++ C W PP P C +
Sbjct: 2023 EPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHF 2082
Query: 138 CDPPGNPVHGYFEG---NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWS 184
C+ P + + E F GS +S+ C + + L + +C+ G+W+
Sbjct: 2083 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWN 2133
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/148 (28%), Positives = 63/148 (42%), Gaps = 2/148 (1%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 104
T+ C +GY L G L C + WD C+ +C P + F + I +
Sbjct: 2914 TFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQY 2973
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
C Y L G++ +CL + +W+ P C C P +G G +F G C
Sbjct: 2974 QCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIE-YGTVNGTDFDCGKAARIQC 3032
Query: 165 EDRYYLVGVQEQQC-VDGEWSSALPVCK 191
+ L+G+ E C DG+WSS P C+
Sbjct: 3033 FKGFKLLGLSEITCEADGQWSSGFPHCE 3060
Score = 68.9 bits (167), Expect = 4e-12
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 3/155 (1%)
Query: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCN 107
C KG+ L+G + C A +W + C C ++ F S + IT+ C
Sbjct: 3032 CFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCR 3091
Query: 108 DHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDR 167
Y+++GS+ C E W+ P+P+C+ C P + + G T S + C +
Sbjct: 3092 SGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEG 3151
Query: 168 YYL-VGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 200
Y + C DG W C ++ P PE
Sbjct: 3152 YTMDTDTDTFTCQKDGRWFPERISCS-PKKCPLPE 3185
Score = 67.0 bits (162), Expect = 1e-11
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
Query: 91 SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE 150
++S + K+ C+ + L G+ CL W P P C+ C P +G+
Sbjct: 1643 TASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHS 1702
Query: 151 GNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQE 195
++F GST++Y C + YYL+G C D G W+ P C + E
Sbjct: 1703 ADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1748
Score = 66.2 bits (160), Expect = 3e-11
Identities = 58/211 (27%), Positives = 87/211 (41%), Gaps = 18/211 (8%)
Query: 21 HCPELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 78
HCP L P +N F+ C G+ LVG + C + W + + CR+
Sbjct: 377 HCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVR 436
Query: 79 HCPDPVLVNGEFSSSGPVNVSDKITFM--CNDHYILKGSNRSQCLEDHTWAPPFPICKSR 136
CP S + K T + C++ Y L+GS++ C + W P P C R
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVER 496
Query: 137 DCD----PPGNPVHGYFEGNNFTLGSTISYY-CEDRYYLVGVQEQ-QC-VDGEWSSAL-- 187
C P + + G TI Y C + L GV+E +C G+W+ +
Sbjct: 497 HCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQA 556
Query: 188 PVCKLIQEAPKPECEKAL----LAFQESKNL 214
VCK + EAP+ C K + L Q+S N+
Sbjct: 557 AVCKDV-EAPQINCPKDIEAKTLEQQDSANV 586
Score = 65.5 bits (158), Expect = 4e-11
Identities = 53/227 (23%), Positives = 80/227 (35%), Gaps = 49/227 (21%)
Query: 21 HCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR---- 76
HC P++N + + Y C G+ + G C S W ++ C
Sbjct: 2555 HCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDC 2613
Query: 77 -------LGHC-----------------------PDP------VLVNGEFSSSGPVNVSD 100
G C P P V E + P S
Sbjct: 2614 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 2673
Query: 101 K------ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF 154
+++ CN Y L G+ C ED TW P C S +CD P P +G+
Sbjct: 2674 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTET 2733
Query: 155 TLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQ-EAPKP 199
++GS + Y C+ + L G + C++ +WS A P C+ I + P P
Sbjct: 2734 SMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNP 2780
Score = 63.5 bits (153), Expect = 2e-10
Identities = 43/188 (22%), Positives = 77/188 (40%), Gaps = 10/188 (5%)
Query: 21 HCPELPP-----VDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNT--TT 73
H E PP + S+ AK G ++ ++ C++G+ L + C +W+ + +
Sbjct: 2081 HFCEKPPSVSYSILESVSKAKFAAGSVV-SFKCMEGFVLNTSAKIECMRGGQWNPSPMSI 2139
Query: 74 ECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
+C C +P + ++S + + + CN + +KG +S C W+ P P C
Sbjct: 2140 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2199
Query: 134 KSRDCDPPGNPVHGYFEGNNFTL-GSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCK 191
C P +G+ E + S + Y C Y VG C + W S P+
Sbjct: 2200 HPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMC 2259
Query: 192 LIQEAPKP 199
+ + KP
Sbjct: 2260 VPLDCGKP 2267
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/217 (23%), Positives = 71/217 (32%), Gaps = 54/217 (24%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 104
TY C +G+ L G L C + +WD C HC P + F + I +
Sbjct: 2521 TYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIY 2580
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-------------GYFE- 150
C + + G C E+ W+ P C DC G P H GYFE
Sbjct: 2581 SCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC---GLPPHIDFGDCTKLKDDQGYFEQ 2636
Query: 151 -----------------------------------GNNFTLGSTISYYCEDRYYLVGVQE 175
+NF G+ +SY C Y L+G
Sbjct: 2637 EDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPV 2696
Query: 176 QQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQES 211
C DG W+ + P C I+ E L F E+
Sbjct: 2697 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTET 2733
Score = 62.0 bits (149), Expect = 5e-10
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 29 DNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNG 88
+N++ KE + C +G+ L G + CN + W T+ +C C P V
Sbjct: 3365 ENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVEN 3424
Query: 89 EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 135
+ D IT+ C Y+L+G RS CLE+ TW P PIC++
Sbjct: 3425 AIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICRA 3470
Score = 61.6 bits (148), Expect = 6e-10
Identities = 37/161 (22%), Positives = 61/161 (37%), Gaps = 2/161 (1%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Y C GY L G + C ++ W ++ C C PV+ G + + +
Sbjct: 2973 YQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGT-DFDCGKAARIQ 3031
Query: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCE 165
C + L G + C D W+ FP C+ C + + + + I+Y C
Sbjct: 3032 CFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCR 3091
Query: 166 DRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKPECEKAL 205
Y + G + C + G WS PVC+ + P A+
Sbjct: 3092 SGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAV 3132
Score = 35.4 bits (80), Expect = 0.047
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 137 DCDPPGNPV-HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQ 194
DC G V H + GS ++ +C+ + LVG Q C++ G+W+ LP C+ I
Sbjct: 1630 DCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERIS 1689
Query: 195 EAPKPECE 202
P E
Sbjct: 1690 CGVPPPLE 1697
Score = 29.3 bits (64), Expect = 3.4
Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 16/49 (32%)
Query: 132 ICKSRDCDPPGNPVHGYF----------------EGNNFTLGSTISYYC 164
+ K C+ P PV+G F EG +FT GST YYC
Sbjct: 721 VIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYC 769
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 90.5 bits (223), Expect = 1e-18
Identities = 59/194 (30%), Positives = 87/194 (44%), Gaps = 26/194 (13%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGT---YVCIKG------YHLVGKKTLFCNASKE----W 68
CP P + N +E GT Y C G + L+G+ T+ C ++ + W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 69 DNTTTECRLG----HCPDPVLVNGEFSSSG---PVNVSDKITFMCNDHYILKGSNRSQCL 121
C+L C + NG + SG P +D +TF C + LKGS++ +C
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANG-YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 122 EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQC 178
D+TW P P+C+ + C P HG G N F G T+ Y C+ Y LVG + C
Sbjct: 646 ADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
Query: 179 V-DGEWSSALPVCK 191
+ G WS + P C+
Sbjct: 705 MPSGNWSPSAPRCE 718
Score = 88.6 bits (218), Expect = 5e-18
Identities = 60/207 (28%), Positives = 91/207 (43%), Gaps = 26/207 (12%)
Query: 11 VAW-RVSASDE-HCPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKT 59
VAW ++ +E CP PP+ N + + G TY C + L+G+ T
Sbjct: 263 VAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGEST 322
Query: 60 LFCNASKE----WDNTTTECRLG----HCPDPVLVNGEFSSSGP--VNVSDKITFMCNDH 109
L C + W C L CP P ++ G S +D + F C
Sbjct: 323 LRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFG 382
Query: 110 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCED 166
+ LKGS + +C TW P P+C+ ++C P N ++G E + F G++I Y C
Sbjct: 383 FTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNP 441
Query: 167 RYYLVGVQEQQCV-DGEWSSALPVCKL 192
Y LVG + QC +G W+ +P CK+
Sbjct: 442 GYVLVGEESIQCTSEGVWTPPVPQCKV 468
Score = 83.2 bits (204), Expect = 2e-16
Identities = 55/191 (28%), Positives = 85/191 (44%), Gaps = 20/191 (10%)
Query: 21 HCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKE----WDNTTT 73
HC P + N E + G +Y C +G++L+G+K L C + + W +
Sbjct: 777 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSP 836
Query: 74 ECR----LGHCPDPVLVNGEF--SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWA 127
+C + CP+P + +G + + +D + CN +I+ GS +C D+TW
Sbjct: 837 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 896
Query: 128 PPFPICKSR---DCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-D 180
P P C + C PP +G G N F+ G +I Y C+ Y LVG C +
Sbjct: 897 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 956
Query: 181 GEWSSALPVCK 191
G WS P CK
Sbjct: 957 GTWSQPAPHCK 967
Score = 74.7 bits (182), Expect = 7e-14
Identities = 58/210 (27%), Positives = 86/210 (40%), Gaps = 25/210 (11%)
Query: 15 VSASDEHCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNT 71
VS CP LP + N ++ V G TY C GY LVG+K + C +S +W
Sbjct: 147 VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAV 206
Query: 72 TTECRLGHCPD-PVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWA 127
C C NG+ + V F C++ Y L+G S+C+ + W
Sbjct: 207 PPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT 266
Query: 128 PPFPICKSRDCDPPGNPVHGYFEGN---NFTLGSTISYYCED------RYYLVGVQEQQC 178
P+C+ C P ++G GN N + GS ++Y C+ + L+G +C
Sbjct: 267 -KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRC 325
Query: 179 V-----DGEWSSALPVCKLIQEA---PKPE 200
G WS P C+L A P P+
Sbjct: 326 TVDSQKTGTWSGPAPRCELSTSAVQCPHPQ 355
Score = 74.7 bits (182), Expect = 7e-14
Identities = 51/168 (30%), Positives = 68/168 (40%), Gaps = 17/168 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Y C GY LVG K++ C S W + C C E + V + +
Sbjct: 688 YTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE-ETCQHVRQSLQELPAGSRVEL---VNTS 743
Query: 106 CNDHYILKGSNRSQC--LEDHTWAPPFPICKSRDCDPPGNPVHGYFEG---NNFTLGSTI 160
C D Y L G C E+ W P+CK C PP V+G G NF G+ +
Sbjct: 744 CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEV 803
Query: 161 SYYCEDRYYLVGVQEQQCVD-----GEWSSALPVC---KLIQEAPKPE 200
SY C+ +YL+G ++ QC G WS P C + P PE
Sbjct: 804 SYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 851
Score = 73.6 bits (179), Expect = 2e-13
Identities = 51/190 (26%), Positives = 85/190 (44%), Gaps = 21/190 (11%)
Query: 22 CPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE----WDNTTTE 74
C PP+ N S + G ++ Y C + L+G+K+L C + WD +
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVI-RYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 75 C----RLGHCPDPVLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPP 129
C + CP+P++ G + S P D +TF C ++ + G+ C ++ W P
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 130 -FPICKS-RDCDPPGNPV--HGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-DG 181
P C S + P P+ +G+ N G +++Y CE Y LVG + C+ G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 182 EWSSALPVCK 191
+WS+ P C+
Sbjct: 202 KWSAVPPTCE 211
Score = 71.2 bits (173), Expect = 8e-13
Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDK---I 102
Y C +GY LVG+ L C W C+ +C P ++G P + +
Sbjct: 937 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVV 996
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
T C D Y+L+GS +SQC DH W PP +C+SR P
Sbjct: 997 TLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 1034
Score = 69.7 bits (169), Expect = 2e-12
Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 15/162 (9%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSD--KIT 103
+ C+ G+ L G K + CNA W+ + C P ++NG+ V I
Sbjct: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
Query: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPG-----NPVHGYFEGNNFTLGS 158
+ CN Y+L G QC + W PP P CK C+ G P H + +
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD------ 490
Query: 159 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKP 199
++ C + Y L G Q+C W + +CK I P P
Sbjct: 491 -VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPP 531
Score = 68.9 bits (167), Expect = 4e-12
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 12/161 (7%)
Query: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECR----LGHCPDPVLVNGEFSSSGPVNVSD--K 101
C G+ + G + + C+ W C +G P P NG + S
Sbjct: 875 CNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMS 934
Query: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTLG 157
I + C+ Y+L G C + TW+ P P CK +C P + + G +G + G
Sbjct: 935 ILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYG 993
Query: 158 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAP 197
+ ++ CED Y L G + QC D +W+ L VC+ AP
Sbjct: 994 AVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 1034
Score = 65.1 bits (157), Expect = 6e-11
Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 20/163 (12%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVN--VSDKIT 103
Y C GY LVG++++ C + W +C++ C G + P + V +
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE----ATGRQLLTKPQHQFVRPDVN 492
Query: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN---NFTLGSTI 160
C + Y L GS +C W +CK C PP +G G+ +F G+T+
Sbjct: 493 SSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTV 552
Query: 161 SYYCED------RYYLVGVQEQQCVD-----GEWSSALPVCKL 192
+Y C + L+G +C G WS P+CKL
Sbjct: 553 TYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 88.6 bits (218), Expect = 5e-18
Identities = 60/207 (28%), Positives = 91/207 (43%), Gaps = 26/207 (12%)
Query: 11 VAW-RVSASDE-HCPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKT 59
VAW ++ +E CP PP+ N + + G TY C + L+G+ T
Sbjct: 263 VAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGEST 322
Query: 60 LFCNASKE----WDNTTTECRLG----HCPDPVLVNGEFSSSGP--VNVSDKITFMCNDH 109
L C + W C L CP P ++ G S +D + F C
Sbjct: 323 LRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFG 382
Query: 110 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCED 166
+ LKGS + +C TW P P+C+ ++C P N ++G E + F G++I Y C
Sbjct: 383 FTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNP 441
Query: 167 RYYLVGVQEQQCV-DGEWSSALPVCKL 192
Y LVG + QC +G W+ +P CK+
Sbjct: 442 GYVLVGEESIQCTSEGVWTPPVPQCKV 468
Score = 85.5 bits (210), Expect = 4e-17
Identities = 58/201 (28%), Positives = 86/201 (42%), Gaps = 27/201 (13%)
Query: 22 CPELPPVDNSIFVAKEVEGQILGT---YVCIKG------YHLVGKKTLFCNASKE----W 68
CP P + N +E GT Y C G + L+G+ T+ C ++ + W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 69 DNTTTECRLG----HCPDPVLVNGEFSSSG---PVNVSDKITFMCNDHYILKGSNRSQCL 121
C+L C + NG + SG P +D +TF C + LKGS++ +C
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANG-YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 122 EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG 181
D+TW P P+C+ C + G+ L +T C+D Y L G Q C D
Sbjct: 646 ADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNT---SCQDGYQLTGHAYQMCQDA 702
Query: 182 E---WSSALPVCKLIQEAPKP 199
E W +P+CK+I P P
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPP 723
Score = 83.2 bits (204), Expect = 2e-16
Identities = 55/191 (28%), Positives = 85/191 (44%), Gaps = 20/191 (10%)
Query: 21 HCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKE----WDNTTT 73
HC P + N E + G +Y C +G++L+G+K L C + + W +
Sbjct: 718 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSP 777
Query: 74 ECR----LGHCPDPVLVNGEF--SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWA 127
+C + CP+P + +G + + +D + CN +I+ GS +C D+TW
Sbjct: 778 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 837
Query: 128 PPFPICKSR---DCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-D 180
P P C + C PP +G G N F+ G +I Y C+ Y LVG C +
Sbjct: 838 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 897
Query: 181 GEWSSALPVCK 191
G WS P CK
Sbjct: 898 GTWSQPAPHCK 908
Score = 74.7 bits (182), Expect = 7e-14
Identities = 58/210 (27%), Positives = 86/210 (40%), Gaps = 25/210 (11%)
Query: 15 VSASDEHCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNT 71
VS CP LP + N ++ V G TY C GY LVG+K + C +S +W
Sbjct: 147 VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAV 206
Query: 72 TTECRLGHCPD-PVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWA 127
C C NG+ + V F C++ Y L+G S+C+ + W
Sbjct: 207 PPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT 266
Query: 128 PPFPICKSRDCDPPGNPVHGYFEGN---NFTLGSTISYYCED------RYYLVGVQEQQC 178
P+C+ C P ++G GN N + GS ++Y C+ + L+G +C
Sbjct: 267 -KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRC 325
Query: 179 V-----DGEWSSALPVCKLIQEA---PKPE 200
G WS P C+L A P P+
Sbjct: 326 TVDSQKTGTWSGPAPRCELSTSAVQCPHPQ 355
Score = 74.3 bits (181), Expect = 9e-14
Identities = 49/169 (28%), Positives = 66/169 (39%), Gaps = 16/169 (9%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 104
T+ C G+ L G + C A WD C C E + V + +
Sbjct: 627 TFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL---VNT 683
Query: 105 MCNDHYILKGSNRSQC--LEDHTWAPPFPICKSRDCDPPGNPVHGYFEG---NNFTLGST 159
C D Y L G C E+ W P+CK C PP V+G G NF G+
Sbjct: 684 SCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNE 743
Query: 160 ISYYCEDRYYLVGVQEQQCVD-----GEWSSALPVC---KLIQEAPKPE 200
+SY C+ +YL+G ++ QC G WS P C + P PE
Sbjct: 744 VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 792
Score = 73.6 bits (179), Expect = 2e-13
Identities = 51/190 (26%), Positives = 85/190 (44%), Gaps = 21/190 (11%)
Query: 22 CPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE----WDNTTTE 74
C PP+ N S + G ++ Y C + L+G+K+L C + WD +
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVI-RYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 75 C----RLGHCPDPVLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPP 129
C + CP+P++ G + S P D +TF C ++ + G+ C ++ W P
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 130 -FPICKS-RDCDPPGNPV--HGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-DG 181
P C S + P P+ +G+ N G +++Y CE Y LVG + C+ G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 182 EWSSALPVCK 191
+WS+ P C+
Sbjct: 202 KWSAVPPTCE 211
Score = 71.2 bits (173), Expect = 8e-13
Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDK---I 102
Y C +GY LVG+ L C W C+ +C P ++G P + +
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVV 937
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
T C D Y+L+GS +SQC DH W PP +C+SR P
Sbjct: 938 TLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 975
Score = 69.7 bits (169), Expect = 2e-12
Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 15/162 (9%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSD--KIT 103
+ C+ G+ L G K + CNA W+ + C P ++NG+ V I
Sbjct: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
Query: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPG-----NPVHGYFEGNNFTLGS 158
+ CN Y+L G QC + W PP P CK C+ G P H + +
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD------ 490
Query: 159 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKP 199
++ C + Y L G Q+C W + +CK I P P
Sbjct: 491 -VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPP 531
Score = 68.9 bits (167), Expect = 4e-12
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 12/161 (7%)
Query: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECR----LGHCPDPVLVNGEFSSSGPVNVSD--K 101
C G+ + G + + C+ W C +G P P NG + S
Sbjct: 816 CNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMS 875
Query: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTLG 157
I + C+ Y+L G C + TW+ P P CK +C P + + G +G + G
Sbjct: 876 ILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYG 934
Query: 158 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAP 197
+ ++ CED Y L G + QC D +W+ L VC+ AP
Sbjct: 935 AVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 975
Score = 65.1 bits (157), Expect = 6e-11
Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 20/163 (12%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVN--VSDKIT 103
Y C GY LVG++++ C + W +C++ C G + P + V +
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE----ATGRQLLTKPQHQFVRPDVN 492
Query: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN---NFTLGSTI 160
C + Y L GS +C W +CK C PP +G G+ +F G+T+
Sbjct: 493 SSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTV 552
Query: 161 SYYCED------RYYLVGVQEQQCVD-----GEWSSALPVCKL 192
+Y C + L+G +C G WS P+CKL
Sbjct: 553 TYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
>gi|67782358 complement factor B preproprotein [Homo sapiens]
Length = 764
Score = 88.2 bits (217), Expect = 6e-18
Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 39 EGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT---------ECRLGHCPDPV-LVNG 88
EGQ L YVC G++ +T C ++ W T ECR HCP P NG
Sbjct: 54 EGQAL-EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
Query: 89 EFSSSGPV-NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--CDPPGNPV 145
E+ P NVSD+I+F C D Y L+GS C + W+ IC + C PG P+
Sbjct: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
Query: 146 HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCK--LIQEAPKPECE 202
G+ + L +++Y+C L G Q + C + G WS P C+ + + P+ E
Sbjct: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
Query: 203 KALLAFQES 211
L + E+
Sbjct: 233 AFLSSLTET 241
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 8/120 (6%)
Query: 21 HCPELPPVDNSIFVAKE----VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR 76
HCP +N + + V +I ++ C GY L G C + W T C
Sbjct: 102 HCPRPHDFENGEYWPRSPYYNVSDEI--SFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 77 --LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK 134
G+C +P + G + D +T+ C+ L+GS R C E +W+ P C+
Sbjct: 160 NGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 86.7 bits (213), Expect = 2e-17
Identities = 44/161 (27%), Positives = 71/161 (44%), Gaps = 11/161 (6%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC-----PDPVLVNGEFSSSGPVNVS 99
T+ C +G+ L+G ++L C +S WDN C+ C P V S +G
Sbjct: 269 TFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFK 328
Query: 100 DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-----GNNF 154
F C + ++L+G + +C W P+C++ C NP GY +F
Sbjct: 329 SSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSF 388
Query: 155 TLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQ 194
GS+ + CE + L G + QC GEW + P C+ ++
Sbjct: 389 RYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVR 429
Score = 71.2 bits (173), Expect = 8e-13
Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 11/160 (6%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC-----PDPVLVNGEFSSSGPVNVSD 100
+ C +G+ L G + C +W C C P+ +N S+SG
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGS 392
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-----YFEGNNFT 155
F C ++LKGS R QC W P C++ CD P G + FT
Sbjct: 393 SCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFT 452
Query: 156 LGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 194
S+ ++ CE+ + L G + +C G+W+ +P C++++
Sbjct: 453 YKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVK 492
Score = 68.9 bits (167), Expect = 4e-12
Identities = 44/158 (27%), Positives = 68/158 (43%), Gaps = 12/158 (7%)
Query: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL--VNGE---FSSSGPVNVSDKI 102
C +GY +T+ C +S EW C + C D V NG F + G +
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVEC-DAVTNPANGFVECFQNPGSFPWNTTC 268
Query: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-----YFEGNNFTLG 157
TF C + + L G+ QC W P CK+ C P +G + FT
Sbjct: 269 TFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFK 328
Query: 158 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQ 194
S+ ++ CE+ + L G + +C G+W+ +PVC+ Q
Sbjct: 329 SSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQ 366
Score = 65.1 bits (157), Expect = 6e-11
Identities = 43/162 (26%), Positives = 61/162 (37%), Gaps = 9/162 (5%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC-----PDPVLVNGEFSSSGPVNVSD 100
+ C +G+ L G K L C + EWDN C C P LV S G
Sbjct: 396 FSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKS 455
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNP--VHGYFEGNNFTLGS 158
F C + + L GS + +C W P C+ C P ++ G G+
Sbjct: 456 SCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP-VFGT 514
Query: 159 TISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKP 199
+ C + + L G + C G WS LP C+ E+ P
Sbjct: 515 VCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIP 556
Score = 64.7 bits (156), Expect = 7e-11
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 14/119 (11%)
Query: 80 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 139
C P+ G FS + ++S C+ Y+ QC+ W+ P P C +CD
Sbjct: 193 CSHPL---GNFSYNSSCSIS------CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECD 243
Query: 140 PPGNPVHGYFE----GNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLI 193
NP +G+ E +F +T ++ CE+ + L+G Q QC G W + P CK +
Sbjct: 244 AVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAV 302
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 83.2 bits (204), Expect = 2e-16
Identities = 60/211 (28%), Positives = 96/211 (45%), Gaps = 19/211 (9%)
Query: 19 DEHCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
++ C +LP + N E + G TY C GY +VG TL C W + C
Sbjct: 742 NDSCSDLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Query: 76 -RLGHCPDPVLV--NGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAP 128
++ +C DP V + S + V I + CN ++L+GS+ C T W
Sbjct: 801 EKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTS 860
Query: 129 PFPICKSRD---CDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE- 182
P C S + CD PG P +GY + G ++++ C + + L+G +C+ G+
Sbjct: 861 RLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQP 920
Query: 183 --WSSALPVCKLIQEAPKPECEKALLAFQES 211
W+ LPVCK+ Q++ + E A A + S
Sbjct: 921 SHWNGPLPVCKVNQDSFEHALEVAEAAAETS 951
Score = 37.7 bits (86), Expect = 0.010
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 78 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCN-DHYILKGSNRSQCL--EDHTWAPPFPIC 133
GHC +P + NG F++S P N+ + F C+ H + +G +C+ D W P+C
Sbjct: 565 GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
Query: 134 KS 135
++
Sbjct: 625 RA 626
Score = 28.1 bits (61), Expect = 7.6
Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C+ P P G + G ++C Y L G + C++ WSS P+C
Sbjct: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 80.5 bits (197), Expect = 1e-15
Identities = 54/195 (27%), Positives = 78/195 (40%), Gaps = 17/195 (8%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFS---SSGPVNVSD 100
++ C GY + G L C AS W N +C CP + G + S+
Sbjct: 227 SFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQS 286
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTL 156
+F C + + L G QC W P P+CK+ C P G + F
Sbjct: 287 SCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAY 346
Query: 157 GSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAP-------KPECEKALLAF 208
GS+ + C+ Y + G+ +C+D G WS+ LP C+ I P +C +L AF
Sbjct: 347 GSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAF 406
Query: 209 QESKNLC-EAMENFM 222
Q N E FM
Sbjct: 407 QYDTNCSFRCAEGFM 421
Score = 77.0 bits (188), Expect = 1e-14
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 41 QILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL--VNGEFSSSGPVNV 98
Q + ++ C +G LVG L C A+ W++ EC+ C P+L NG + P+
Sbjct: 471 QSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQNGTMTCVQPLGS 529
Query: 99 S---DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN-- 153
S F+C++ Y L G R C W P+C++ C P G + ++
Sbjct: 530 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 589
Query: 154 --FTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKP 199
F +GST + C++ + L G +C G WS+ P CK I P P
Sbjct: 590 GEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTP 638
Score = 75.5 bits (184), Expect = 4e-14
Identities = 45/174 (25%), Positives = 81/174 (46%), Gaps = 19/174 (10%)
Query: 35 AKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSG 94
AK + Q ++ C +G+ LVG + + C AS W C+ C + E S G
Sbjct: 279 AKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQ-----HLEAPSEG 333
Query: 95 PVNVSDKIT---------FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPV 145
++ +T F C Y ++G + +C++ W+ P P C++ C+P +PV
Sbjct: 334 TMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPV 393
Query: 146 HGYFEGN----NFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQ 194
HG + + F + S+ C + + L G +C + G+W++ PVC+ +Q
Sbjct: 394 HGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQ 447
Score = 63.2 bits (152), Expect = 2e-10
Identities = 45/147 (30%), Positives = 64/147 (43%), Gaps = 13/147 (8%)
Query: 74 ECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
EC P VL+N G + + + +F C D Y + G ++ +CL W P C
Sbjct: 199 ECGELELPQHVLMNCSHPL-GNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 134 KSRDCDPPGNPVHG----YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALP 188
+ C P P G F S+ S+ CE+ + LVG + QC G W++ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 189 VCKLIQ----EAPKP---ECEKALLAF 208
VCK +Q EAP +C L AF
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAF 344
Score = 62.0 bits (149), Expect = 5e-10
Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 9/159 (5%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFSSSGPVNV---SD 100
++ C +G+ L G + C+ +W C+ C D PV + S P
Sbjct: 413 SFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQS 472
Query: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTL 156
+F CN+ +L G++ QCL W P C++ C P +P +G + +
Sbjct: 473 VCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSY 532
Query: 157 GSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 194
ST + C++ Y L G + C G W+ + P+C+ I+
Sbjct: 533 KSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIK 571
Score = 60.5 bits (145), Expect = 1e-09
Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 17/166 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL-VNGEFSSS---GPVNVSDK 101
++C +GY L G + L C S W ++ C CP+ G S G NV
Sbjct: 538 FICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGST 597
Query: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK--------SRDCDPPGNPVHGYF---- 149
F C++ + L+G N +C W+ P CK C P G
Sbjct: 598 CHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRH 657
Query: 150 EGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQ 194
F +T + C + L+G C G+W++ P C+ ++
Sbjct: 658 HPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVK 703
Score = 54.7 bits (130), Expect = 8e-08
Identities = 47/200 (23%), Positives = 76/200 (38%), Gaps = 25/200 (12%)
Query: 22 CPELPPVDNSIFVAKEVEGQI-LGT---YVCIKGYHLVGKKTLFCNASKEWDNTTTECR- 76
CPEL + + G+ +G+ + C G+ L G + C S W T C+
Sbjct: 572 CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKG 631
Query: 77 LGHCPDPVLVNGEFSSSGPVNV-----------SDKITFMCNDHYILKGSNRSQCLEDHT 125
+ P P + ++ G + + F CN + L G + C
Sbjct: 632 IASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQ 691
Query: 126 WAPPFPICKSRDCDP--PGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCVD- 180
W P C++ C P+ NF+ GS S++C + L G + C +
Sbjct: 692 WTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQEN 751
Query: 181 GEWSSALPVCK----LIQEA 196
G WS+ +P C+ IQEA
Sbjct: 752 GHWSTTVPTCQAGPLTIQEA 771
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 79.7 bits (195), Expect = 2e-15
Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 10/158 (6%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C GY L G L C +W C + C D + L NG + + K+
Sbjct: 316 YSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVD 375
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGST 159
F+C++ + LKGS+ S C+ + W P+C+ + C+ P PV+G + +GS
Sbjct: 376 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSR 435
Query: 160 ISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
I+Y C + L+G +C+ WS P+C+ I
Sbjct: 436 INYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQI 473
Score = 67.8 bits (164), Expect = 9e-12
Identities = 46/181 (25%), Positives = 77/181 (42%), Gaps = 19/181 (10%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + C A +W+ C P
Sbjct: 233 PNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPP 292
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD- 139
P +++ E + N S ++ + C Y L+GS C W+P P C+ + CD
Sbjct: 293 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDD 352
Query: 140 -----PPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVC 190
P G+ + N LG+ + + C++ + L G CV + W+S++PVC
Sbjct: 353 FLGQLPNGHVLFPL----NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 408
Query: 191 K 191
+
Sbjct: 409 E 409
Score = 61.6 bits (148), Expect = 6e-10
Identities = 62/240 (25%), Positives = 94/240 (39%), Gaps = 28/240 (11%)
Query: 8 CLMVAWRVSASDE----HCPELP-PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC 62
CL + SA D+ C P PV+ V K+++ + Y C KGY L+G + C
Sbjct: 78 CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATC 137
Query: 63 NASKE---WDNTTTECRLGHCP-DPVLVNGEFSSSGP--VNVSDKITFMCN------DHY 110
S WDN T C C P + NG+F+S + +T+ CN +
Sbjct: 138 IISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVF 197
Query: 111 ILKGSNRSQCLEDH----TWAPPFPIC-KSRDCDPPGNPVHGYFEGNN---FTLGSTISY 162
L G C W+ P P C C PP N +G +N F+L + +
Sbjct: 198 ELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPP-NVENGILVSDNRSLFSLNEVVEF 256
Query: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENF 221
C+ + + G +C +W LP C + + P P+ A ++ N E F
Sbjct: 257 RCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQ-PPPDVLHAERTQRDKDNFSPGQEVF 315
Score = 37.4 bits (85), Expect = 0.012
Identities = 27/124 (21%), Positives = 51/124 (41%), Gaps = 16/124 (12%)
Query: 27 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNAS---KEWDNTTTECRLGHCPD- 82
PV+ + V ++ Y C G+ L+G + C S W C+ CP+
Sbjct: 419 PVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNP 478
Query: 83 PVLVNGEFSSS--GPVNVSDKITFMCNDH-------YILKGSNRSQCLEDH---TWAPPF 130
P ++NG + + G + ++++ C+ H ++ S + E H W+ P
Sbjct: 479 PAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPA 538
Query: 131 PICK 134
P C+
Sbjct: 539 PRCE 542
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3
[Homo sapiens]
Length = 840
Score = 78.2 bits (191), Expect = 6e-15
Identities = 60/207 (28%), Positives = 91/207 (43%), Gaps = 19/207 (9%)
Query: 19 DEHCPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
++ CPELPP + A + G +L TY C GY L+G L C W C
Sbjct: 571 NDTCPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Query: 76 -RLGHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAP 128
++ C DP + NG +S V + + C Y L+G+ C T W+
Sbjct: 630 QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSD 689
Query: 129 PFPIC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG--- 181
P C K C PG P +GY +++ G ++ ++C + + L+G CV G
Sbjct: 690 RVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 749
Query: 182 EWSSALPVCKLIQEA-PKPECEKALLA 207
+W+S P+CK+ Q P + E LA
Sbjct: 750 QWTSQPPLCKVTQTTDPSRQLEGGNLA 776
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 45 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 75
T+ C GY L G++TL C W+ T C
Sbjct: 243 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 78.2 bits (191), Expect = 6e-15
Identities = 60/207 (28%), Positives = 91/207 (43%), Gaps = 19/207 (9%)
Query: 19 DEHCPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
++ CPELPP + A + G +L TY C GY L+G L C W C
Sbjct: 641 NDTCPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Query: 76 -RLGHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAP 128
++ C DP + NG +S V + + C Y L+G+ C T W+
Sbjct: 700 QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSD 759
Query: 129 PFPIC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG--- 181
P C K C PG P +GY +++ G ++ ++C + + L+G CV G
Sbjct: 760 RVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 819
Query: 182 EWSSALPVCKLIQEA-PKPECEKALLA 207
+W+S P+CK+ Q P + E LA
Sbjct: 820 QWTSQPPLCKVTQTTDPSRQLEGGNLA 846
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 45 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 75
T+ C GY L G++TL C W+ T C
Sbjct: 313 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/189 (28%), Positives = 83/189 (43%), Gaps = 21/189 (11%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIKG------YHLVGKKTLFCNASKE----W 68
C P + N F++ E G TY C G + LVG+ +++C ++ + W
Sbjct: 1516 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1575
Query: 69 DNTTTECRLGH-CPDPVLVNGEFSSSGP--VNVSDKITFMCNDHYILKGSNRSQCLEDHT 125
+C + + C P + NG S ++++ + F C +++KG R +C +
Sbjct: 1576 SGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 1635
Query: 126 WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DG 181
W P P C SR C PP +HG +NF+ G + Y CE Y L G C G
Sbjct: 1636 WEPELPSC-SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQG 1694
Query: 182 EWSSALPVC 190
+WS P C
Sbjct: 1695 DWSPEAPRC 1703
Score = 77.4 bits (189), Expect = 1e-14
Identities = 42/124 (33%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 78
CP P + N ++ V + G +Y+C GY LVGK +FC W C+
Sbjct: 2298 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEV 2357
Query: 79 HCPDPVLVNG---EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 135
+C P+ +NG E + D +T C D Y L+GS SQC D W PP C S
Sbjct: 2358 NCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTS 2417
Query: 136 RDCD 139
R D
Sbjct: 2418 RTHD 2421
Score = 72.8 bits (177), Expect = 3e-13
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 27 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV 86
P + S F E+ + C G+ +VG T+ C + W C P P ++
Sbjct: 2053 PGNRSFFTLTEII-----RFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEIL 2107
Query: 87 NGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP-PGN 143
+GE + S N S ++ + C Y L+G+ C W+P P C + CD G
Sbjct: 2108 HGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQ 2167
Query: 144 PVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
HG N LG+ +S+ C++ + L G CV W+S++PVC+ I
Sbjct: 2168 LPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 2222
Score = 71.6 bits (174), Expect = 6e-13
Identities = 51/192 (26%), Positives = 80/192 (41%), Gaps = 27/192 (14%)
Query: 22 CPELPPVDNSIFVAKE---VEGQILGTYVCIKG------YHLVGKKTLFCNASKE----W 68
C P + N F + + TY C G + LVG+++++C + + W
Sbjct: 1969 CEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVW 2028
Query: 69 DN------TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE 122
+ +T +C + + V G S +++ I F C +++ GS+ QC
Sbjct: 2029 SSPPPRCISTNKCTAPEVENAIRVPGNRSF---FTLTEIIRFRCQPGFVMVGSHTVQCQT 2085
Query: 123 DHTWAPPFPICKSRDCDPPGNPVHG---YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 179
+ W P P C SR C PP +HG +NF+ G + Y CE Y L G C
Sbjct: 2086 NGRWGPKLPHC-SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT 2144
Query: 180 -DGEWSSALPVC 190
G+WS P C
Sbjct: 2145 PQGDWSPEAPRC 2156
Score = 71.2 bits (173), Expect = 8e-13
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 11/179 (6%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 1591 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1650
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P +++GE + S N S ++ + C Y L+G+ C W+P P C + CD
Sbjct: 1651 PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1710
Query: 141 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
G HG N LG+ +S+ C++ + L G CV W++++PVC+ I
Sbjct: 1711 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI 1769
Score = 71.2 bits (173), Expect = 8e-13
Identities = 53/179 (29%), Positives = 74/179 (41%), Gaps = 21/179 (11%)
Query: 46 YVCIKGYHLVGKK-TLFCNASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVNVSDKIT 103
Y C GY GK ++ C + W + CR C P P NG + +
Sbjct: 1874 YECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1931
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 157
+ CN+ + L GS + CL + TW PIC+ C+PP +G F NN F G
Sbjct: 1932 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNG 1991
Query: 158 STISYYC------EDRYYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKAL 205
+ ++Y C E + LVG + C G WSS P C + PE E A+
Sbjct: 1992 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAI 2050
Score = 70.9 bits (172), Expect = 1e-12
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 19/174 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 324 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 383
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 157
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 443
Query: 158 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 200
T++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 444 KTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 497
Score = 70.9 bits (172), Expect = 1e-12
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 19/174 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 774 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 833
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 157
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 893
Query: 158 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 200
T++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 894 KTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 947
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
Query: 141 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 750
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 810
Query: 141 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 811 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 1201 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 1260
Query: 141 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 1261 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 1319
Score = 68.9 bits (167), Expect = 4e-12
Identities = 46/174 (26%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 1224 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 1283
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 157
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 1284 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 1343
Query: 158 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 200
++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 1344 KAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 1397
Score = 67.8 bits (164), Expect = 9e-12
Identities = 51/197 (25%), Positives = 83/197 (42%), Gaps = 28/197 (14%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTLFCNASKE----W 68
CP P + N K +E G Y C + L+G+ T+ C + + W
Sbjct: 1321 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 1380
Query: 69 DNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL 121
+ C LGHC P L +S P+ S K + C Y + + + CL
Sbjct: 1381 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPEYYGRPFSIT-CL 1437
Query: 122 EDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRYYLVGVQEQQCV- 179
++ W+ P +CK + C P +PV+G + +GS I+Y C + L+G +C+
Sbjct: 1438 DNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL 1497
Query: 180 ---DGEWSSALPVCKLI 193
WS+ P+C+ I
Sbjct: 1498 SGNTAHWSTKPPICQRI 1514
Score = 67.4 bits (163), Expect = 1e-11
Identities = 51/197 (25%), Positives = 83/197 (42%), Gaps = 28/197 (14%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTLFCNASKE----W 68
CP P + N K +E G Y C + L+G+ T+ C + + W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 69 DNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL 121
+ C LGHC P L +S P+ S K + C Y + + + CL
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPEYYGRPFSIT-CL 537
Query: 122 EDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRYYLVGVQEQQCV- 179
++ W+ P +CK + C P +PV+G + +GS I+Y C + L+G +C+
Sbjct: 538 DNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL 597
Query: 180 ---DGEWSSALPVCKLI 193
WS+ P+C+ I
Sbjct: 598 SGNAAHWSTKPPICQRI 614
Score = 67.4 bits (163), Expect = 1e-11
Identities = 51/197 (25%), Positives = 83/197 (42%), Gaps = 28/197 (14%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTLFCNASKE----W 68
CP P + N K +E G Y C + L+G+ T+ C + + W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 69 DNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL 121
+ C LGHC P L +S P+ S K + C Y + + + CL
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPEYYGRPFSIT-CL 987
Query: 122 EDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRYYLVGVQEQQCV- 179
++ W+ P +CK + C P +PV+G + +GS I+Y C + L+G +C+
Sbjct: 988 DNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL 1047
Query: 180 ---DGEWSSALPVCKLI 193
WS+ P+C+ I
Sbjct: 1048 SGNAAHWSTKPPICQRI 1064
Score = 65.5 bits (158), Expect = 4e-11
Identities = 56/216 (25%), Positives = 87/216 (40%), Gaps = 23/216 (10%)
Query: 27 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE---WDNTTTECRLGHCP-D 82
PV+ + V K ++ Y C KGY L+G + C S + WDN T C C
Sbjct: 110 PVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLP 169
Query: 83 PVLVNGEFSSSGPVN--VSDKITFMCNDH------YILKGSNRSQCLEDH----TWAPPF 130
P + NG+F S+ N +T+ CN + L G C + W+ P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 131 PIC-KSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSS 185
P C C PP N +G +N F+L + + C+ + + G + +C +W
Sbjct: 230 PQCIIPNKCTPP-NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 288
Query: 186 ALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENF 221
LP C + + P P+ A ++ N E F
Sbjct: 289 ELPSCSRVCQ-PPPDVLHAERTQRDKDNFSPGQEVF 323
Score = 65.1 bits (157), Expect = 6e-11
Identities = 49/177 (27%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C Y L G +L C +W C + C D + L +G + + K++
Sbjct: 2127 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVS 2186
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF---TLG 157
F+C++ + LKG + S C+ W P+C+ C P ++G G F G
Sbjct: 2187 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYG 2246
Query: 158 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPECEK 203
ISY C+ DR + L+G +C +G WSS P C+L A P K
Sbjct: 2247 KEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPK 2303
Score = 61.2 bits (147), Expect = 8e-10
Identities = 52/221 (23%), Positives = 88/221 (39%), Gaps = 28/221 (12%)
Query: 3 FWCACCLMVAWRVSASDEHC------PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVG 56
F +C + W S+ +++C P P + + + + + Y C +G+ L+G
Sbjct: 1885 FSISCLENLVW--SSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIG 1942
Query: 57 KKTLFCNASKE---WDNTTTECRLGHC-PDPVLVNGEFSSSGPVNVSD--KITFMCN--- 107
+ C S WD C + C P P + NG+F S+ + + +T+ C+
Sbjct: 1943 SPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGP 2002
Query: 108 ---DHYILKGSNRSQCLEDH----TWAPPFPICKSRD-CDPP--GNPVHGYFEGNNFTLG 157
+ L G C W+ P P C S + C P N + + FTL
Sbjct: 2003 DGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLT 2062
Query: 158 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAP 197
I + C+ + +VG QC +G W LP C + + P
Sbjct: 2063 EIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPP 2103
Score = 60.1 bits (144), Expect = 2e-09
Identities = 60/225 (26%), Positives = 85/225 (37%), Gaps = 29/225 (12%)
Query: 6 ACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKK-TLF 61
A +++A V+ + PE P + E E I GTY+ C GY G+ ++
Sbjct: 29 AVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPI-GTYLNYECRPGYS--GRPFSII 85
Query: 62 CNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRS 118
C + W CR C PDPV NG + +I + C Y L GS+ +
Sbjct: 86 CLKNSVWTGAKDRCRRKSCRNPPDPV--NGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSA 143
Query: 119 QCL---EDHTWAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR----- 167
C+ + W PIC C P +G F NF GS ++Y C
Sbjct: 144 TCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRK 203
Query: 168 -YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 206
+ LVG C G WS P C + + P E +L
Sbjct: 204 VFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 248
Score = 53.1 bits (126), Expect = 2e-07
Identities = 42/168 (25%), Positives = 64/168 (38%), Gaps = 22/168 (13%)
Query: 59 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 115
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 590
Query: 116 NRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR-- 167
+ ++C+ W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 591 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 650
Query: 168 ----YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 206
+ LVG C G WS P C + + P E +L
Sbjct: 651 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 698
Score = 53.1 bits (126), Expect = 2e-07
Identities = 42/168 (25%), Positives = 64/168 (38%), Gaps = 22/168 (13%)
Query: 59 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 115
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 983 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 116 NRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR-- 167
+ ++C+ W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 1041 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 1100
Query: 168 ----YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 206
+ LVG C G WS P C + + P E +L
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 1148
Score = 53.1 bits (126), Expect = 2e-07
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 22/168 (13%)
Query: 59 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 115
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 1433 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 1490
Query: 116 NRSQC-LEDHT--WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYC----- 164
+ ++C L +T W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 1491 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1550
Query: 165 -EDRYYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 206
+ LVG C G WS P C + + P E +L
Sbjct: 1551 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 1598
Score = 50.8 bits (120), Expect = 1e-06
Identities = 42/184 (22%), Positives = 74/184 (40%), Gaps = 32/184 (17%)
Query: 45 TYVCIKGYHLVGKKTLFC---NASKEWDNTTTECRLGHCPD-PVLVNGEFSS--SGPVNV 98
++VC +G+ L G C W+N+ C CP+ P ++NG + SG +
Sbjct: 1733 SFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPY 1792
Query: 99 SDKITFMCNDH------YILKGSNRSQCLED----HTWAPPFPIC----KSRDCDPPGN- 143
+I++ C+ H + L G + +C D W+ P P C ++ C P
Sbjct: 1793 GKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQF 1852
Query: 144 -------PVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEA 196
P++ + F +G++++Y C Y+ + WSS C+
Sbjct: 1853 PFASPTIPINDF----EFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCG 1908
Query: 197 PKPE 200
P PE
Sbjct: 1909 PPPE 1912
Score = 49.7 bits (117), Expect = 2e-06
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 14/153 (9%)
Query: 52 YHLVGKKTLFCNASKE----WDNTTTECRLG---HCPDPVLVNGEFSSSGPVNV---SDK 101
++L+G+ ++ C + + W + C L CP P + G V++
Sbjct: 2263 FNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMT 2322
Query: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP--GNPVHGYFEGNN-FTLGS 158
I+++C+ Y+L G C + W+ CK +C P N + E + G
Sbjct: 2323 ISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGD 2382
Query: 159 TISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
++ CED Y L G QC D W L C
Sbjct: 2383 YVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKC 2415
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/189 (28%), Positives = 83/189 (43%), Gaps = 21/189 (11%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIKG------YHLVGKKTLFCNASKE----W 68
C P + N F++ E G TY C G + LVG+ +++C ++ + W
Sbjct: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
Query: 69 DNTTTECRLGH-CPDPVLVNGEFSSSGP--VNVSDKITFMCNDHYILKGSNRSQCLEDHT 125
+C + + C P + NG S ++++ + F C +++KG R +C +
Sbjct: 1126 SGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 1185
Query: 126 WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DG 181
W P P C SR C PP +HG +NF+ G + Y CE Y L G C G
Sbjct: 1186 WEPELPSC-SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQG 1244
Query: 182 EWSSALPVC 190
+WS P C
Sbjct: 1245 DWSPEAPRC 1253
Score = 77.4 bits (189), Expect = 1e-14
Identities = 42/124 (33%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 78
CP P + N ++ V + G +Y+C GY LVGK +FC W C+
Sbjct: 1848 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEV 1907
Query: 79 HCPDPVLVNG---EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 135
+C P+ +NG E + D +T C D Y L+GS SQC D W PP C S
Sbjct: 1908 NCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTS 1967
Query: 136 RDCD 139
R D
Sbjct: 1968 RTHD 1971
Score = 72.8 bits (177), Expect = 3e-13
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 27 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV 86
P + S F E+ + C G+ +VG T+ C + W C P P ++
Sbjct: 1603 PGNRSFFTLTEII-----RFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEIL 1657
Query: 87 NGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP-PGN 143
+GE + S N S ++ + C Y L+G+ C W+P P C + CD G
Sbjct: 1658 HGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQ 1717
Query: 144 PVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
HG N LG+ +S+ C++ + L G CV W+S++PVC+ I
Sbjct: 1718 LPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 1772
Score = 71.6 bits (174), Expect = 6e-13
Identities = 51/192 (26%), Positives = 80/192 (41%), Gaps = 27/192 (14%)
Query: 22 CPELPPVDNSIFVAKE---VEGQILGTYVCIKG------YHLVGKKTLFCNASKE----W 68
C P + N F + + TY C G + LVG+++++C + + W
Sbjct: 1519 CEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVW 1578
Query: 69 DN------TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE 122
+ +T +C + + V G S +++ I F C +++ GS+ QC
Sbjct: 1579 SSPPPRCISTNKCTAPEVENAIRVPGNRSF---FTLTEIIRFRCQPGFVMVGSHTVQCQT 1635
Query: 123 DHTWAPPFPICKSRDCDPPGNPVHG---YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 179
+ W P P C SR C PP +HG +NF+ G + Y CE Y L G C
Sbjct: 1636 NGRWGPKLPHC-SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT 1694
Query: 180 -DGEWSSALPVC 190
G+WS P C
Sbjct: 1695 PQGDWSPEAPRC 1706
Score = 71.2 bits (173), Expect = 8e-13
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 11/179 (6%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P +++GE + S N S ++ + C Y L+G+ C W+P P C + CD
Sbjct: 1201 PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1260
Query: 141 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
G HG N LG+ +S+ C++ + L G CV W++++PVC+ I
Sbjct: 1261 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI 1319
Score = 71.2 bits (173), Expect = 8e-13
Identities = 53/179 (29%), Positives = 74/179 (41%), Gaps = 21/179 (11%)
Query: 46 YVCIKGYHLVGKK-TLFCNASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVNVSDKIT 103
Y C GY GK ++ C + W + CR C P P NG + +
Sbjct: 1424 YECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1481
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 157
+ CN+ + L GS + CL + TW PIC+ C+PP +G F NN F G
Sbjct: 1482 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNG 1541
Query: 158 STISYYC------EDRYYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKAL 205
+ ++Y C E + LVG + C G WSS P C + PE E A+
Sbjct: 1542 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAI 1600
Score = 70.9 bits (172), Expect = 1e-12
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 19/174 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 324 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 383
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 157
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 443
Query: 158 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 200
T++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 444 KTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 497
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
Query: 141 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 26 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 82
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 750
Query: 83 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 810
Query: 141 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 193
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 811 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869
Score = 68.9 bits (167), Expect = 4e-12
Identities = 46/174 (26%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 774 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 833
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 157
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 893
Query: 158 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 200
++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 894 KAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 947
Score = 67.8 bits (164), Expect = 9e-12
Identities = 51/197 (25%), Positives = 83/197 (42%), Gaps = 28/197 (14%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTLFCNASKE----W 68
CP P + N K +E G Y C + L+G+ T+ C + + W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 69 DNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL 121
+ C LGHC P L +S P+ S K + C Y + + + CL
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPEYYGRPFSIT-CL 987
Query: 122 EDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRYYLVGVQEQQCV- 179
++ W+ P +CK + C P +PV+G + +GS I+Y C + L+G +C+
Sbjct: 988 DNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL 1047
Query: 180 ---DGEWSSALPVCKLI 193
WS+ P+C+ I
Sbjct: 1048 SGNTAHWSTKPPICQRI 1064
Score = 67.4 bits (163), Expect = 1e-11
Identities = 51/197 (25%), Positives = 83/197 (42%), Gaps = 28/197 (14%)
Query: 22 CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTLFCNASKE----W 68
CP P + N K +E G Y C + L+G+ T+ C + + W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 69 DNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL 121
+ C LGHC P L +S P+ S K + C Y + + + CL
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPEYYGRPFSIT-CL 537
Query: 122 EDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRYYLVGVQEQQCV- 179
++ W+ P +CK + C P +PV+G + +GS I+Y C + L+G +C+
Sbjct: 538 DNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL 597
Query: 180 ---DGEWSSALPVCKLI 193
WS+ P+C+ I
Sbjct: 598 SGNAAHWSTKPPICQRI 614
Score = 65.5 bits (158), Expect = 4e-11
Identities = 56/216 (25%), Positives = 87/216 (40%), Gaps = 23/216 (10%)
Query: 27 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE---WDNTTTECRLGHCP-D 82
PV+ + V K ++ Y C KGY L+G + C S + WDN T C C
Sbjct: 110 PVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLP 169
Query: 83 PVLVNGEFSSSGPVN--VSDKITFMCNDH------YILKGSNRSQCLEDH----TWAPPF 130
P + NG+F S+ N +T+ CN + L G C + W+ P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 131 PIC-KSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSS 185
P C C PP N +G +N F+L + + C+ + + G + +C +W
Sbjct: 230 PQCIIPNKCTPP-NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 288
Query: 186 ALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENF 221
LP C + + P P+ A ++ N E F
Sbjct: 289 ELPSCSRVCQ-PPPDVLHAERTQRDKDNFSPGQEVF 323
Score = 65.1 bits (157), Expect = 6e-11
Identities = 49/177 (27%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 103
Y C Y L G +L C +W C + C D + L +G + + K++
Sbjct: 1677 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVS 1736
Query: 104 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF---TLG 157
F+C++ + LKG + S C+ W P+C+ C P ++G G F G
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYG 1796
Query: 158 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPECEK 203
ISY C+ DR + L+G +C +G WSS P C+L A P K
Sbjct: 1797 KEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPK 1853
Score = 61.2 bits (147), Expect = 8e-10
Identities = 52/221 (23%), Positives = 88/221 (39%), Gaps = 28/221 (12%)
Query: 3 FWCACCLMVAWRVSASDEHC------PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVG 56
F +C + W S+ +++C P P + + + + + Y C +G+ L+G
Sbjct: 1435 FSISCLENLVW--SSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIG 1492
Query: 57 KKTLFCNASKE---WDNTTTECRLGHC-PDPVLVNGEFSSSGPVNVSD--KITFMCN--- 107
+ C S WD C + C P P + NG+F S+ + + +T+ C+
Sbjct: 1493 SPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGP 1552
Query: 108 ---DHYILKGSNRSQCLEDH----TWAPPFPICKSRD-CDPP--GNPVHGYFEGNNFTLG 157
+ L G C W+ P P C S + C P N + + FTL
Sbjct: 1553 DGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLT 1612
Query: 158 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAP 197
I + C+ + +VG QC +G W LP C + + P
Sbjct: 1613 EIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPP 1653
Score = 60.1 bits (144), Expect = 2e-09
Identities = 60/225 (26%), Positives = 85/225 (37%), Gaps = 29/225 (12%)
Query: 6 ACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKK-TLF 61
A +++A V+ + PE P + E E I GTY+ C GY G+ ++
Sbjct: 29 AVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPI-GTYLNYECRPGYS--GRPFSII 85
Query: 62 CNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRS 118
C + W CR C PDPV NG + +I + C Y L GS+ +
Sbjct: 86 CLKNSVWTGAKDRCRRKSCRNPPDPV--NGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSA 143
Query: 119 QCL---EDHTWAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR----- 167
C+ + W PIC C P +G F NF GS ++Y C
Sbjct: 144 TCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRK 203
Query: 168 -YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 206
+ LVG C G WS P C + + P E +L
Sbjct: 204 VFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 248
Score = 53.1 bits (126), Expect = 2e-07
Identities = 42/168 (25%), Positives = 64/168 (38%), Gaps = 22/168 (13%)
Query: 59 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 115
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 590
Query: 116 NRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR-- 167
+ ++C+ W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 591 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 650
Query: 168 ----YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 206
+ LVG C G WS P C + + P E +L
Sbjct: 651 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 698
Score = 53.1 bits (126), Expect = 2e-07
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 22/168 (13%)
Query: 59 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 115
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 983 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 116 NRSQC-LEDHT--WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYC----- 164
+ ++C L +T W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 1041 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1100
Query: 165 -EDRYYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 206
+ LVG C G WS P C + + P E +L
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 1148
Score = 50.8 bits (120), Expect = 1e-06
Identities = 42/184 (22%), Positives = 74/184 (40%), Gaps = 32/184 (17%)
Query: 45 TYVCIKGYHLVGKKTLFC---NASKEWDNTTTECRLGHCPD-PVLVNGEFSS--SGPVNV 98
++VC +G+ L G C W+N+ C CP+ P ++NG + SG +
Sbjct: 1283 SFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPY 1342
Query: 99 SDKITFMCNDH------YILKGSNRSQCLED----HTWAPPFPIC----KSRDCDPPGN- 143
+I++ C+ H + L G + +C D W+ P P C ++ C P
Sbjct: 1343 GKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQF 1402
Query: 144 -------PVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEA 196
P++ + F +G++++Y C Y+ + WSS C+
Sbjct: 1403 PFASPTIPINDF----EFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCG 1458
Query: 197 PKPE 200
P PE
Sbjct: 1459 PPPE 1462
Score = 49.7 bits (117), Expect = 2e-06
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 14/153 (9%)
Query: 52 YHLVGKKTLFCNASKE----WDNTTTECRLG---HCPDPVLVNGEFSSSGPVNV---SDK 101
++L+G+ ++ C + + W + C L CP P + G V++
Sbjct: 1813 FNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMT 1872
Query: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP--GNPVHGYFEGNN-FTLGS 158
I+++C+ Y+L G C + W+ CK +C P N + E + G
Sbjct: 1873 ISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGD 1932
Query: 159 TISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
++ CED Y L G QC D W L C
Sbjct: 1933 YVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKC 1965
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 77.4 bits (189), Expect = 1e-14
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 18/194 (9%)
Query: 19 DEHCPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
++ CPELPP + A + G +L TY C GY L+G L C W C
Sbjct: 527 NDTCPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Query: 76 -RLGHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAP 128
++ C DP + NG +S V + + C Y L+G+ C T W+
Sbjct: 586 QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSD 645
Query: 129 PFPIC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG--- 181
P C K C PG P +GY +++ G ++ ++C + + L+G CV G
Sbjct: 646 RVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 705
Query: 182 EWSSALPVCKLIQE 195
+W+S P+CK+ E
Sbjct: 706 QWTSQPPLCKVAYE 719
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Score = 32.3 bits (72), Expect = 0.40
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 157 GSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKP 199
G+ ++Y CE Y L+G C D WS+A P C+ I P
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 594
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 45 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 75
T+ C GY L G++TL C W+ T C
Sbjct: 199 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 77.4 bits (189), Expect = 1e-14
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 18/194 (9%)
Query: 19 DEHCPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
++ CPELPP + A + G +L TY C GY L+G L C W C
Sbjct: 571 NDTCPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Query: 76 -RLGHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAP 128
++ C DP + NG +S V + + C Y L+G+ C T W+
Sbjct: 630 QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSD 689
Query: 129 PFPIC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG--- 181
P C K C PG P +GY +++ G ++ ++C + + L+G CV G
Sbjct: 690 RVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 749
Query: 182 EWSSALPVCKLIQE 195
+W+S P+CK+ E
Sbjct: 750 QWTSQPPLCKVAYE 763
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 32.3 bits (72), Expect = 0.40
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 157 GSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKP 199
G+ ++Y CE Y L+G C D WS+A P C+ I P
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 45 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 75
T+ C GY L G++TL C W+ T C
Sbjct: 243 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 71.2 bits (173), Expect = 8e-13
Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 14/179 (7%)
Query: 27 PVDNSIFVAKEVEGQILGTYVCIKGY-HLVGKKTLFCNASKEWDNTTTECRLGHCPDP-V 84
P+D ++ + G L Y C+ GY +TL CN+ EW T C C P
Sbjct: 61 PMDITLTETRFKTGTTL-KYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGE 118
Query: 85 LVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC-LEDH--TWAPPFPICKSRDCDPP 141
L NG+ ++ +I F C++ + L GS S+C ++D W+ P P C+ C PP
Sbjct: 119 LRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPP 178
Query: 142 GNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKLI 193
+ +G G N + G +++Y C+ R+ L+G C G W + P C+ I
Sbjct: 179 PDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKI 237
Score = 62.4 bits (150), Expect = 4e-10
Identities = 49/172 (28%), Positives = 73/172 (42%), Gaps = 21/172 (12%)
Query: 42 ILGT---YVCIKGYHLVGKK--TLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSS---S 93
++GT Y C GY + T+ C + W C CP+P L NGE + S
Sbjct: 323 VVGTVLRYRCHPGYKPTTDEPTTVICQKNLRW-TPYQGCEALCCPEPKLNNGEITQHRKS 381
Query: 94 GPVN-----VSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGY 148
P N D+I+F C++ + C D TW+P P C C+ P HG+
Sbjct: 382 RPANHCVYFYGDEISFSCHE----TSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGH 436
Query: 149 FEGNNFT--LGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEAPK 198
++ ++ I Y C+ Y LVG + C WS+ P CK + P+
Sbjct: 437 YKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPE 488
Score = 57.4 bits (137), Expect = 1e-08
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 13/137 (9%)
Query: 45 TYVCIKGYHLVGKKTLFCNASKE----WDNTTTECRLGHCPDPVLVNGEFSSS-GPV-NV 98
TY C + L+G ++ C E W + C C P + +GE S GP+ N
Sbjct: 200 TYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNY 259
Query: 99 SDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-------G 151
D I F C ++L+GS+ C D W P P C+ C + H +E
Sbjct: 260 KDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKE 319
Query: 152 NNFTLGSTISYYCEDRY 168
+ + +G+ + Y C Y
Sbjct: 320 DVYVVGTVLRYRCHPGY 336
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVS-DKITF 104
Y C KGY LVG+ L C+ S W +C+ C P LVNG S V + +T
Sbjct: 452 YECDKGYILVGQAKLSCSYS-HWSAPAPQCK-ALCRKPELVNGRLSVDKDQYVEPENVTI 509
Query: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICK 134
C+ Y + G C + TW P P C+
Sbjct: 510 QCDSGYGVVGPQSITCSGNRTWYPEVPKCE 539
Score = 43.1 bits (100), Expect = 2e-04
Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 22/140 (15%)
Query: 77 LGHC-PDPVLVNGEFSSSGPVNVS---------DKITFMCNDHYILKGSNRS-QCLEDHT 125
LG+C P P L S + P++++ + + C Y+ S ++ C D
Sbjct: 47 LGNCGPPPTL-----SFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGE 101
Query: 126 WAPPFPICKSRDCDPPGNPVHGYFE-GNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-- 182
W C + C PG +G E + + GS I + C + ++L+G +C +
Sbjct: 102 WVYN-TFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRG 160
Query: 183 --WSSALPVCKLIQEAPKPE 200
WS LP C++++ P P+
Sbjct: 161 VGWSHPLPQCEIVKCKPPPD 180
>gi|14550407 complement component 2 isoform 1 preproprotein [Homo
sapiens]
Length = 752
Score = 69.7 bits (169), Expect = 2e-12
Identities = 63/236 (26%), Positives = 92/236 (38%), Gaps = 18/236 (7%)
Query: 7 CCLMVAWRVSASDEHCPELPPVDNSIFVAKE--VEGQILGTYVCIKGYHLVGKKTLFCNA 64
C L + ++ S CP+ + F G +L TY C +G + L C +
Sbjct: 9 CLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLL-TYSCPQGLYPSPASRL-CKS 66
Query: 65 SKEWDN-------TTTECRLGHCPDPV-LVNGEFSSS-GPVNVSDKITFMCNDHYILKGS 115
S +W + C+ CP PV NG ++ G V ++F C D +IL+GS
Sbjct: 67 SGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGS 126
Query: 116 NRSQCLEDHTWAPPFPICKSR--DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGV 173
QC + W +C + C PG + G F G + Y C L G
Sbjct: 127 PVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGS 186
Query: 174 QEQQCV-DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKES 228
E++C +G WS P+C+ PE L S L N Q+ KES
Sbjct: 187 SERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHML--GATNPTQKTKES 240
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 68.2 bits (165), Expect = 7e-12
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 12/158 (7%)
Query: 46 YVCIKGYHLVGKKT--LFCNASKEWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSDKI 102
Y C GY + L C + +W C+ CP+P + NG+ G + I
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATI 186
Query: 103 TFMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEG--NNFTLG 157
+F CN Y L GS S CL W+ P P C+ C P +G +G +++
Sbjct: 187 SFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYR 246
Query: 158 STISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCK 191
+++Y C + ++G C +GEWS P C+
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 52.4 bits (124), Expect = 4e-07
Identities = 39/176 (22%), Positives = 68/176 (38%), Gaps = 15/176 (8%)
Query: 45 TYVCIKGYHLVG--KKTLFCNASKEWDNTTTECRLGHCPDPVLVNGE-----FSSSGPVN 97
TY C + + + K ++ C +W + C C P +N + +
Sbjct: 62 TYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRS-CEVPTRLNSASLKQPYITQNYFP 120
Query: 98 VSDKITFMCNDHYILKGS--NRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNF 154
V + + C Y + S + CL++ W+ CK + C PG +G +
Sbjct: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
Query: 155 TLGSTISYYCEDRYYLVGVQEQQCVDG----EWSSALPVCKLIQEAPKPECEKALL 206
G+TIS+ C Y L G C+ +WS LP C+ I P+ + ++
Sbjct: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGII 236
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 21 HCPELPPVDNSIFVAKEVEGQILG-----TYVCIKGYHLVGKKTLFC---NASKEWDNTT 72
+CP P +DN I + E G TY C KG+ ++G+ +++C N EW
Sbjct: 224 YCPAPPQIDNGII---QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Query: 73 TECR 76
ECR
Sbjct: 281 PECR 284
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 68.2 bits (165), Expect = 7e-12
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 12/158 (7%)
Query: 46 YVCIKGYHLVGKKT--LFCNASKEWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSDKI 102
Y C GY + L C + +W C+ CP+P + NG+ G + I
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATI 186
Query: 103 TFMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEG--NNFTLG 157
+F CN Y L GS S CL W+ P P C+ C P +G +G +++
Sbjct: 187 SFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYR 246
Query: 158 STISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCK 191
+++Y C + ++G C +GEWS P C+
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 52.4 bits (124), Expect = 4e-07
Identities = 39/176 (22%), Positives = 68/176 (38%), Gaps = 15/176 (8%)
Query: 45 TYVCIKGYHLVG--KKTLFCNASKEWDNTTTECRLGHCPDPVLVNGE-----FSSSGPVN 97
TY C + + + K ++ C +W + C C P +N + +
Sbjct: 62 TYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRS-CEVPTRLNSASLKQPYITQNYFP 120
Query: 98 VSDKITFMCNDHYILKGS--NRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNF 154
V + + C Y + S + CL++ W+ CK + C PG +G +
Sbjct: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
Query: 155 TLGSTISYYCEDRYYLVGVQEQQCVDG----EWSSALPVCKLIQEAPKPECEKALL 206
G+TIS+ C Y L G C+ +WS LP C+ I P+ + ++
Sbjct: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGII 236
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 21 HCPELPPVDNSIFVAKEVEGQILG-----TYVCIKGYHLVGKKTLFC---NASKEWDNTT 72
+CP P +DN I + E G TY C KG+ ++G+ +++C N EW
Sbjct: 224 YCPAPPQIDNGII---QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Query: 73 TECR 76
ECR
Sbjct: 281 PECR 284
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 68.2 bits (165), Expect = 7e-12
Identities = 54/191 (28%), Positives = 80/191 (41%), Gaps = 19/191 (9%)
Query: 19 DEHCPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
++ CPELP + N S + V G ++ TY C GY +VG L C W C
Sbjct: 707 NDTCPELPEIPNGWKSPSQPELVHGTVV-TYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Query: 76 -RLGHCPDP--VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAP 128
R+ C DP V + SS V + ++C+ ++L GS+ C + W+
Sbjct: 766 QRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSD 825
Query: 129 PFPIC---KSRDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-- 181
P C + + C P +G E G+TI + C Y L G +CV G
Sbjct: 826 RAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHP 885
Query: 182 -EWSSALPVCK 191
WS P+C+
Sbjct: 886 SHWSDPPPICR 896
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 46 YVCIKGYHLVGKKTLFCN----ASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVN--- 97
Y+C +G+ L+G L C+ S +W + +C L P L E + P
Sbjct: 797 YICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLH 856
Query: 98 -VSDKITFMCNDHYILKGSNRSQCLEDHT--WAPPFPICKSRDCD 139
I F C Y+LKG +C+ H W+ P PIC++ D
Sbjct: 857 PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLD 901
Score = 37.7 bits (86), Expect = 0.010
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 78 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCNDHYIL-KGSNRSQCLEDH--TWAPPFPIC 133
GHC +P + G FSSS P V + F C+ Y L +GS +C++ H W P C
Sbjct: 530 GHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
Query: 134 KS 135
++
Sbjct: 590 RA 591
Score = 30.0 bits (66), Expect = 2.0
Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
C P P +G + G + ++C Y L G + C++ W S PVC
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 412
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 68.2 bits (165), Expect = 7e-12
Identities = 54/191 (28%), Positives = 80/191 (41%), Gaps = 19/191 (9%)
Query: 19 DEHCPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
++ CPELP + N S + V G ++ TY C GY +VG L C W C
Sbjct: 707 NDTCPELPEIPNGWKSPSQPELVHGTVV-TYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Query: 76 -RLGHCPDP--VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAP 128
R+ C DP V + SS V + ++C+ ++L GS+ C + W+
Sbjct: 766 QRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSD 825
Query: 129 PFPIC---KSRDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-- 181
P C + + C P +G E G+TI + C Y L G +CV G
Sbjct: 826 RAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHP 885
Query: 182 -EWSSALPVCK 191
WS P+C+
Sbjct: 886 SHWSDPPPICR 896
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 46 YVCIKGYHLVGKKTLFCN----ASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVN--- 97
Y+C +G+ L+G L C+ S +W + +C L P L E + P
Sbjct: 797 YICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLH 856
Query: 98 -VSDKITFMCNDHYILKGSNRSQCLEDHT--WAPPFPICKSRDCD 139
I F C Y+LKG +C+ H W+ P PIC++ D
Sbjct: 857 PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLD 901
Score = 37.7 bits (86), Expect = 0.010
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 78 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCNDHYIL-KGSNRSQCLEDH--TWAPPFPIC 133
GHC +P + G FSSS P V + F C+ Y L +GS +C++ H W P C
Sbjct: 530 GHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
Query: 134 KS 135
++
Sbjct: 590 RA 591
Score = 30.0 bits (66), Expect = 2.0
Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 190
C P P +G + G + ++C Y L G + C++ W S PVC
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 412
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,477,704
Number of Sequences: 37866
Number of extensions: 563772
Number of successful extensions: 2676
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1530
Number of HSP's gapped (non-prelim): 586
length of query: 251
length of database: 18,247,518
effective HSP length: 100
effective length of query: 151
effective length of database: 14,460,918
effective search space: 2183598618
effective search space used: 2183598618
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.