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Search of human proteins with 62899047
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62899047 RAD50 interactor 1 [Homo sapiens]
(792 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62899047 RAD50 interactor 1 [Homo sapiens] 1567 0.0
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 39 0.025
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 36 0.16
gi|189217904 RPGRIP1-like isoform b [Homo sapiens] 35 0.27
gi|118442834 RPGRIP1-like isoform a [Homo sapiens] 35 0.27
gi|46852390 coiled-coil domain containing 6 [Homo sapiens] 35 0.27
gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom... 35 0.36
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom... 35 0.36
gi|62899065 centrosomal protein 72 kDa [Homo sapiens] 35 0.36
gi|229577185 epidermal growth factor receptor pathway substrate ... 34 0.61
gi|4503593 epidermal growth factor receptor pathway substrate 15... 34 0.61
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 33 1.4
gi|112293287 tudor domain containing 7 [Homo sapiens] 33 1.4
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 32 1.8
gi|5730009 ret finger protein [Homo sapiens] 32 2.3
gi|116089284 fibrous sheath interacting protein 1 [Homo sapiens] 32 2.3
gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isofo... 32 3.0
gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isofo... 32 3.0
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 32 3.0
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 32 3.0
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 32 3.0
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 32 3.0
gi|113722133 senataxin [Homo sapiens] 32 3.0
gi|28274703 family with sequence similarity 9, member C [Homo sa... 32 3.0
gi|213385323 anaphase-promoting complex subunit 5 isoform b [Hom... 31 3.9
gi|20127553 anaphase-promoting complex subunit 5 isoform a [Homo... 31 3.9
gi|111955326 MLX interacting protein [Homo sapiens] 31 3.9
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 31 3.9
gi|145553976 zinc finger, CW type with coiled-coil domain 2 isof... 31 3.9
gi|148664197 coiled-coil domain containing 40 [Homo sapiens] 31 3.9
>gi|62899047 RAD50 interactor 1 [Homo sapiens]
Length = 792
Score = 1567 bits (4057), Expect = 0.0
Identities = 792/792 (100%), Positives = 792/792 (100%)
Query: 1 MLPAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFI 60
MLPAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFI
Sbjct: 1 MLPAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFI 60
Query: 61 EKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQF 120
EKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQF
Sbjct: 61 EKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQF 120
Query: 121 LEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLM 180
LEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLM
Sbjct: 121 LEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLM 180
Query: 181 TNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKDKLTSDFEEILAQLH 240
TNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKDKLTSDFEEILAQLH
Sbjct: 181 TNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKDKLTSDFEEILAQLH 240
Query: 241 WPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASP 300
WPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASP
Sbjct: 241 WPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASP 300
Query: 301 SVILPIQVMLTPLQKRFRYHFRGNRQTNVLSKPEWYLAQVLMWIGNHTEFLDEKIQPILD 360
SVILPIQVMLTPLQKRFRYHFRGNRQTNVLSKPEWYLAQVLMWIGNHTEFLDEKIQPILD
Sbjct: 301 SVILPIQVMLTPLQKRFRYHFRGNRQTNVLSKPEWYLAQVLMWIGNHTEFLDEKIQPILD 360
Query: 361 KVGSLVNARLEFSRGLMMLVLEKLATDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPG 420
KVGSLVNARLEFSRGLMMLVLEKLATDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPG
Sbjct: 361 KVGSLVNARLEFSRGLMMLVLEKLATDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPG 420
Query: 421 TFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAAWVSQYKDITDVDEMKVPDCAE 480
TFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAAWVSQYKDITDVDEMKVPDCAE
Sbjct: 421 TFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAAWVSQYKDITDVDEMKVPDCAE 480
Query: 481 TFMTLLLVITDRYKNLPTASRKLQFLELQKDLVDDFRIRLTQVMKEETRASLGFRYCAIL 540
TFMTLLLVITDRYKNLPTASRKLQFLELQKDLVDDFRIRLTQVMKEETRASLGFRYCAIL
Sbjct: 481 TFMTLLLVITDRYKNLPTASRKLQFLELQKDLVDDFRIRLTQVMKEETRASLGFRYCAIL 540
Query: 541 NAVNYISTVLADWADNVFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLE 600
NAVNYISTVLADWADNVFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLE
Sbjct: 541 NAVNYISTVLADWADNVFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLE 600
Query: 601 RLKHDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLL 660
RLKHDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLL
Sbjct: 601 RLKHDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLL 660
Query: 661 QLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYC 720
QLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYC
Sbjct: 661 QLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYC 720
Query: 721 KRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLPATAALNEVGIYKLAQQDVEIL 780
KRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLPATAALNEVGIYKLAQQDVEIL
Sbjct: 721 KRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLPATAALNEVGIYKLAQQDVEIL 780
Query: 781 LNLRTNWPNTGK 792
LNLRTNWPNTGK
Sbjct: 781 LNLRTNWPNTGK 792
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 38.5 bits (88), Expect = 0.025
Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 20/187 (10%)
Query: 33 NVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQV 92
N+ + G + SE L S + +E E+ + LK KKL+ +EQR L+ Q+
Sbjct: 818 NLQTIQGILERSETETKQRLSSQIEK-LEHEISH-LK--KKLENEVEQRHTLTRNLDVQL 873
Query: 93 LTISSEIPK------RIRSALKNAEESKQFLNQFL-EQETHLFSAINSHLLTAQPW-MDD 144
L ++ + LKNA++ L Q L E + S + QP +D
Sbjct: 874 LDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKED 933
Query: 145 LGTMISQIEEIERHLAYLKWISQIEELSDNIQQY-LMTNNVPEAASTLVSMAE-----LD 198
+ ++SQ+ + E + LK +++ + N++QY M ++ E+ + + E ++
Sbjct: 934 VDDLVSQLRQTEEQVNDLK--ERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIE 991
Query: 199 IKLQESS 205
++L+ES+
Sbjct: 992 VRLKESA 998
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 35.8 bits (81), Expect = 0.16
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 12/102 (11%)
Query: 22 ERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQR 81
E+ N ++K+D + L K+V A I++++ ++ K+++KL E
Sbjct: 394 EKFNRDQKADQDRLDLEERKKVE-----------TEAKIKQKLREIEENQKRIEKLEEYI 442
Query: 82 TVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQ 123
T SK LEEQ + E+ + + A + +E + LNQ +EQ
Sbjct: 443 TTSKQSLEEQK-KLEGELTEEVEMAKRRIDEINKELNQVMEQ 483
>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
Length = 1235
Score = 35.0 bits (79), Expect = 0.27
Identities = 47/166 (28%), Positives = 71/166 (42%), Gaps = 13/166 (7%)
Query: 68 LKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLN--QFLEQET 125
L S+K ++ IE+ LE++ + K SA A E + L Q Q
Sbjct: 331 LHSMKFSERRIEELQDRINDLEKERELLKENYDKLYDSAFSAAHEEQWKLKEQQLKVQIA 390
Query: 126 HLFSAINSHLLTAQPWMDDLGTMISQIEEI-----ERHLAYLKWISQIEELSDNIQQYLM 180
L +A+ S L +D L T Q E++ E L YL+ Q++EL I+ Y
Sbjct: 391 QLETALKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQ 450
Query: 181 TNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKD 226
N++ + +S A L IK Q+ L F+ VK +I KD
Sbjct: 451 ENDI---NADELSEALLLIKAQKEQKNGDLSFL---VKVDSEINKD 490
>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
Length = 1315
Score = 35.0 bits (79), Expect = 0.27
Identities = 47/166 (28%), Positives = 71/166 (42%), Gaps = 13/166 (7%)
Query: 68 LKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLN--QFLEQET 125
L S+K ++ IE+ LE++ + K SA A E + L Q Q
Sbjct: 331 LHSMKFSERRIEELQDRINDLEKERELLKENYDKLYDSAFSAAHEEQWKLKEQQLKVQIA 390
Query: 126 HLFSAINSHLLTAQPWMDDLGTMISQIEEI-----ERHLAYLKWISQIEELSDNIQQYLM 180
L +A+ S L +D L T Q E++ E L YL+ Q++EL I+ Y
Sbjct: 391 QLETALKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQ 450
Query: 181 TNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKD 226
N++ + +S A L IK Q+ L F+ VK +I KD
Sbjct: 451 ENDI---NADELSEALLLIKAQKEQKNGDLSFL---VKVDSEINKD 490
>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
Length = 474
Score = 35.0 bits (79), Expect = 0.27
Identities = 33/156 (21%), Positives = 65/156 (41%), Gaps = 20/156 (12%)
Query: 28 EKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDK-------LIEQ 80
EK + +T + K + + +L ++ E +V +K +KKL+ +EQ
Sbjct: 135 EKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQ 194
Query: 81 RTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQP 140
K+ LE + + R+ + E K+ L + L+Q ++A P
Sbjct: 195 LRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQP-----------VSAPP 243
Query: 141 WMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQ 176
D+ I E + RH+ +LK +++E L ++
Sbjct: 244 SPRDISMEIDSPENMMRHIRFLK--NEVERLKKQLR 277
>gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo
sapiens]
Length = 1194
Score = 34.7 bits (78), Expect = 0.36
Identities = 48/203 (23%), Positives = 84/203 (41%), Gaps = 37/203 (18%)
Query: 5 GEIGA-SPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKE 63
G+ G+ +PAAP S G ++ S I+ V S P ++ I ++
Sbjct: 62 GDYGSYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVS------------PMHLQ-HIREQ 108
Query: 64 VGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQ 123
+ LK LK+L++ + RT+ +Q++ VL EE +Q ++Q Q
Sbjct: 109 MAIALKRLKELEEQV--RTIPVLQVKISVLQ----------------EEKRQLVSQLKNQ 150
Query: 124 ETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLMTNN 183
S IN + + + + + Q+ R L +I EE + ++Q T
Sbjct: 151 RAA--SQINVCGVRKRSYSAGNASQLEQLSRARRSGGEL-YIDYEEEEMETVEQ--STQR 205
Query: 184 VPEAASTLVSMAELDIKLQESSC 206
+ E M L+ K+Q+SSC
Sbjct: 206 IKEFRQLTADMQALEQKIQDSSC 228
>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
sapiens]
Length = 1352
Score = 34.7 bits (78), Expect = 0.36
Identities = 48/203 (23%), Positives = 84/203 (41%), Gaps = 37/203 (18%)
Query: 5 GEIGA-SPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKE 63
G+ G+ +PAAP S G ++ S I+ V S P ++ I ++
Sbjct: 220 GDYGSYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVS------------PMHLQ-HIREQ 266
Query: 64 VGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQ 123
+ LK LK+L++ + RT+ +Q++ VL EE +Q ++Q Q
Sbjct: 267 MAIALKRLKELEEQV--RTIPVLQVKISVLQ----------------EEKRQLVSQLKNQ 308
Query: 124 ETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLMTNN 183
S IN + + + + + Q+ R L +I EE + ++Q T
Sbjct: 309 RAA--SQINVCGVRKRSYSAGNASQLEQLSRARRSGGEL-YIDYEEEEMETVEQ--STQR 363
Query: 184 VPEAASTLVSMAELDIKLQESSC 206
+ E M L+ K+Q+SSC
Sbjct: 364 IKEFRQLTADMQALEQKIQDSSC 386
>gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
Length = 647
Score = 34.7 bits (78), Expect = 0.36
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 10/137 (7%)
Query: 64 VGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQ 123
VG D+ SL K ++ R + Q + + SE+ + K ++ +Q L++ LE+
Sbjct: 470 VGEDVGSLALESKSLQSRLAEQQQQHAREM---SEVTAELHHTHKELDDLRQHLDKSLEE 526
Query: 124 ETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQY----L 179
+ L S + S + D T+ QI ++ + L +I EL +++ Y
Sbjct: 527 NSRLKSLLLSMKKEVKS-ADTAATLNLQIAGLQTSVKRL--CGEIVELKQHLEHYDKIQE 583
Query: 180 MTNNVPEAASTLVSMAE 196
+T + E+ S+LVS E
Sbjct: 584 LTQMLQESHSSLVSTNE 600
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 33.9 bits (76), Expect = 0.61
Identities = 30/140 (21%), Positives = 57/140 (40%), Gaps = 5/140 (3%)
Query: 28 EKSDINVTVLIGSKQ-VSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKM 86
++ + N+ L KQ V E D D A +E+++ K + +LI
Sbjct: 64 QRENTNLQKLQAQKQQVQELLDELDEQK---AQLEEQLKEVRKKCAEEAQLISSLKAELT 120
Query: 87 QLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLG 146
E Q+ T E+ K R L ++ L + +E + HL +Q + +
Sbjct: 121 SQESQISTYEEELAKA-REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQ 179
Query: 147 TMISQIEEIERHLAYLKWIS 166
+ +++++E H + L W S
Sbjct: 180 MKLMEMKDLENHNSQLNWCS 199
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 33.9 bits (76), Expect = 0.61
Identities = 30/140 (21%), Positives = 57/140 (40%), Gaps = 5/140 (3%)
Query: 28 EKSDINVTVLIGSKQ-VSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKM 86
++ + N+ L KQ V E D D A +E+++ K + +LI
Sbjct: 378 QRENTNLQKLQAQKQQVQELLDELDEQK---AQLEEQLKEVRKKCAEEAQLISSLKAELT 434
Query: 87 QLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLG 146
E Q+ T E+ K R L ++ L + +E + HL +Q + +
Sbjct: 435 SQESQISTYEEELAKA-REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQ 493
Query: 147 TMISQIEEIERHLAYLKWIS 166
+ +++++E H + L W S
Sbjct: 494 MKLMEMKDLENHNSQLNWCS 513
>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
Length = 3639
Score = 32.7 bits (73), Expect = 1.4
Identities = 52/239 (21%), Positives = 100/239 (41%), Gaps = 15/239 (6%)
Query: 60 IEKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQ 119
+EKEV +L +L +++E T+ ++ +R L A + FL +
Sbjct: 3229 MEKEVARLQTEACRLGQLHPAAPGGLAKVQEAWATLQAKAQER-GQWLAQAAQGHAFLGR 3287
Query: 120 FLEQETHLFSAINSHLLTAQPWMDDLG---TMISQIEEIERHLAYLKWISQIEELSDNIQ 176
QE ++ L +++ +D+ ++ Q EE+ + + + Q ++L Q
Sbjct: 3288 C--QELLAWAQERQELASSEELAEDVAGAEQLLGQHEELGQEIRECRL--QAQDLRQEGQ 3343
Query: 177 QYLMTNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKDKLTSDFEEIL 236
Q L+ N+ +A + EL+ +LQE L + R + + L+ +L E L
Sbjct: 3344 Q-LVDNSHFMSAEVTECLQELEGRLQELEEAWALRWQRCAESWGLQKLRQRL-EQAEAWL 3401
Query: 237 AQLHWPFIAPPQSQTVG-----LSRPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQL 290
A + P +V L R ++ + E F Q+ K + ELL +P++L
Sbjct: 3402 ACWEGLLLKPDYGHSVSDVELLLHRHQDLEKLLAAQEEKFAQMQKTEMEQELLLQPQEL 3460
Score = 30.8 bits (68), Expect = 5.1
Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 9/95 (9%)
Query: 87 QLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLG 146
QLE+ + + +E +R R L+ A+E++QFL + LE + L A H+L + +D+G
Sbjct: 2941 QLEKAMAHLRAEAARR-RLLLQQAQEAQQFLTELLEAGSWL--AERGHVLDS----EDMG 2993
Query: 147 TMISQIEEIERHLAYLKWISQIEELSDNIQQYLMT 181
+ + R L K +E S I++ T
Sbjct: 2994 HSAEATQALLRRLEATK--RDLEAFSPRIERLQQT 3026
>gi|112293287 tudor domain containing 7 [Homo sapiens]
Length = 1098
Score = 32.7 bits (73), Expect = 1.4
Identities = 36/136 (26%), Positives = 56/136 (41%), Gaps = 17/136 (12%)
Query: 169 EELSDNIQQYLMTNNVPEAASTLVSMAELDIKLQESSCTHLLG-FMRATVKFWHKILKDK 227
+E+SDN+ Q + NV AS M E+ +++E H G ++ F+ ++ K+
Sbjct: 209 KEMSDNLNQTVEKPNVKPPASYTYKMDEVQNRIKEILNKHNNGIWISKLPHFYKELYKED 268
Query: 228 LTSDFEEILAQL-HWPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDEL--- 283
L + IL Q HWP I + +P S + QLL+ + E
Sbjct: 269 LN---QGILQQFEHWPHICT-------VEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPL 318
Query: 284 --LTEPKQLPEKYSLP 297
L PKQ P P
Sbjct: 319 SPLPGPKQTPPLKGCP 334
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 32.3 bits (72), Expect = 1.8
Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 3/117 (2%)
Query: 45 EGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIP--KR 102
EG +L S VS IEKE + + + EQ + +E +V T+ ++ K+
Sbjct: 470 EGNQRRNLESTVSQ-IEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKK 528
Query: 103 IRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHL 159
+ + A E L + LE+ L + + + ++ ISQ+E + R L
Sbjct: 529 VSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNREL 585
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 32.0 bits (71), Expect = 2.3
Identities = 32/157 (20%), Positives = 67/157 (42%), Gaps = 12/157 (7%)
Query: 3 PAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEK 62
P GE+G C + + K E+ + + V+ + G L V F E
Sbjct: 89 PGGEMGV------CEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKE- 141
Query: 63 EVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNA-----EESKQFL 117
++ N L LK++ L ++R Q ++L+++ ++I + E + L
Sbjct: 142 QIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLL 201
Query: 118 NQFLEQETHLFSAINSHLLTAQPWMDDLGTMISQIEE 154
+ E + ++++IN + + L ++I+Q+EE
Sbjct: 202 ARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEE 238
>gi|116089284 fibrous sheath interacting protein 1 [Homo sapiens]
Length = 581
Score = 32.0 bits (71), Expect = 2.3
Identities = 24/109 (22%), Positives = 56/109 (51%), Gaps = 13/109 (11%)
Query: 18 ESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKL 77
ES E+ L E+ L+ + +SE +D L ++ ++ + ++ +KKLDK+
Sbjct: 74 ESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKE-----LDSQLQDAIQKMKKLDKI 128
Query: 78 IEQRTVSKMQLEEQVLTISSEIPKRIRSA--------LKNAEESKQFLN 118
+ ++ + ++++Q L + ++ + I+SA + E +K+FL+
Sbjct: 129 LAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLS 177
>gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isoform
a precursor [Homo sapiens]
Length = 839
Score = 31.6 bits (70), Expect = 3.0
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 9/76 (11%)
Query: 718 HYCKRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLP-------ATAALNE--VG 768
H C +P+ Y +HIK IVL +G K L P A AL + +
Sbjct: 521 HNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLA 580
Query: 769 IYKLAQQDVEILLNLR 784
K Q++ E+L NL+
Sbjct: 581 ARKDFQREAELLTNLQ 596
>gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isoform
b precursor [Homo sapiens]
Length = 825
Score = 31.6 bits (70), Expect = 3.0
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 9/76 (11%)
Query: 718 HYCKRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLP-------ATAALNE--VG 768
H C +P+ Y +HIK IVL +G K L P A AL + +
Sbjct: 521 HNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLA 580
Query: 769 IYKLAQQDVEILLNLR 784
K Q++ E+L NL+
Sbjct: 581 ARKDFQREAELLTNLQ 596
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 31.6 bits (70), Expect = 3.0
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 13/110 (11%)
Query: 68 LKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHL 127
LK L+K +EQ K +++EQ +++ +R++ A K A+E+ + +++E+
Sbjct: 111 LKELEKHKIQLEQVQEWKSKMQEQ----QADLQRRLKEARKEAKEALEAKERYMEEMADT 166
Query: 128 FSAINSHLL-------TAQPWMDDLGTMISQIEEIERHLAYLKWISQIEE 170
AI L A+ ++ + +++E+ L LK ++IEE
Sbjct: 167 ADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK--AEIEE 214
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 31.6 bits (70), Expect = 3.0
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 13/110 (11%)
Query: 68 LKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHL 127
LK L+K +EQ K +++EQ +++ +R++ A K A+E+ + +++E+
Sbjct: 225 LKELEKHKIQLEQVQEWKSKMQEQ----QADLQRRLKEARKEAKEALEAKERYMEEMADT 280
Query: 128 FSAINSHLL-------TAQPWMDDLGTMISQIEEIERHLAYLKWISQIEE 170
AI L A+ ++ + +++E+ L LK ++IEE
Sbjct: 281 ADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK--AEIEE 328
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 31.6 bits (70), Expect = 3.0
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 13/110 (11%)
Query: 68 LKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHL 127
LK L+K +EQ K +++EQ +++ +R++ A K A+E+ + +++E+
Sbjct: 111 LKELEKHKIQLEQVQEWKSKMQEQ----QADLQRRLKEARKEAKEALEAKERYMEEMADT 166
Query: 128 FSAINSHLL-------TAQPWMDDLGTMISQIEEIERHLAYLKWISQIEE 170
AI L A+ ++ + +++E+ L LK ++IEE
Sbjct: 167 ADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK--AEIEE 214
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 31.6 bits (70), Expect = 3.0
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 13/110 (11%)
Query: 68 LKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHL 127
LK L+K +EQ K +++EQ +++ +R++ A K A+E+ + +++E+
Sbjct: 245 LKELEKHKIQLEQVQEWKSKMQEQ----QADLQRRLKEARKEAKEALEAKERYMEEMADT 300
Query: 128 FSAINSHLL-------TAQPWMDDLGTMISQIEEIERHLAYLKWISQIEE 170
AI L A+ ++ + +++E+ L LK ++IEE
Sbjct: 301 ADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK--AEIEE 348
>gi|113722133 senataxin [Homo sapiens]
Length = 2677
Score = 31.6 bits (70), Expect = 3.0
Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 21 DERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKK------- 73
D++ L DIN+ L K ++ L S V+ ++KE+ + ++++ K
Sbjct: 2030 DKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDY 2089
Query: 74 -LDKLIEQRT-------VSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQET 125
LD+L QR + + +L+E + +S E + + S +K + Q + E+
Sbjct: 2090 QLDELSRQRALCRGGREIQRQELDENISKVSKE-RQELASKIKEVQGRPQKTQSIIILES 2148
Query: 126 HL 127
H+
Sbjct: 2149 HI 2150
>gi|28274703 family with sequence similarity 9, member C [Homo
sapiens]
Length = 166
Score = 31.6 bits (70), Expect = 3.0
Identities = 23/99 (23%), Positives = 46/99 (46%), Gaps = 13/99 (13%)
Query: 17 SESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDK 76
S +ERK + E + +VT ++G+ S+ ++ G D K L+ +
Sbjct: 26 SHEHEERKPVTETKEGDVT-----------DEHGERGSFAET--DEHTGVDTKELEDIAA 72
Query: 77 LIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQ 115
I++ +K + E++ SEI RI++ L+ + +Q
Sbjct: 73 DIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQ 111
>gi|213385323 anaphase-promoting complex subunit 5 isoform b [Homo
sapiens]
Length = 643
Score = 31.2 bits (69), Expect = 3.9
Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Query: 262 EIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASPSVILPIQVMLTPLQKRFRYHF 321
E + L+ L KL+ ++ +++ + E Y +SP++ LP+ + L K +R +
Sbjct: 447 EAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQY 506
Query: 322 RGNRQTNVLSKPEWYLAQVLMWIGNHT-EFLDEKIQPILDKVGSLVNARLEF 372
+ L+ AQ+++ I L I+PIL L R F
Sbjct: 507 LASETVLNLA-----FAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMF 553
>gi|20127553 anaphase-promoting complex subunit 5 isoform a [Homo
sapiens]
Length = 755
Score = 31.2 bits (69), Expect = 3.9
Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Query: 262 EIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASPSVILPIQVMLTPLQKRFRYHF 321
E + L+ L KL+ ++ +++ + E Y +SP++ LP+ + L K +R +
Sbjct: 559 EAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQY 618
Query: 322 RGNRQTNVLSKPEWYLAQVLMWIGNHT-EFLDEKIQPILDKVGSLVNARLEF 372
+ L+ AQ+++ I L I+PIL L R F
Sbjct: 619 LASETVLNLA-----FAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMF 665
>gi|111955326 MLX interacting protein [Homo sapiens]
Length = 919
Score = 31.2 bits (69), Expect = 3.9
Identities = 56/220 (25%), Positives = 88/220 (40%), Gaps = 48/220 (21%)
Query: 100 PKRIRSALKN-------AEESKQF--------LNQFLEQETHLFSAINSHLLTAQPWMDD 144
PK + +ALKN AE+ ++F LN + S + SH +T Q ++
Sbjct: 711 PKNV-AALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNN----SKLTSHAITLQKTVEY 765
Query: 145 LGTMISQIEEIERHLAYLKWISQIEELSDNI---QQYLMTNNVPEAASTLVSMAELDIKL 201
+ + + +++ L+ +IEEL+ I QQ L VP M ++
Sbjct: 766 ITKLQQERGQMQEEARRLR--EEIEELNATIISCQQLLPATGVPVTRRQFDHMKDM---F 820
Query: 202 QESSCTHLLGFMRATVKFW-HKILKDKLTSDFEEI-----LAQLHWPFIAPPQSQTVGLS 255
E T L KFW I+ L F+ + L +LH ++ S
Sbjct: 821 DEYVKTRTL----QNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHC---S 873
Query: 256 RPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYS 295
P P + S L +L TS +LT+P QLPE+ S
Sbjct: 874 LPILRPMVLSTLR-------QLSTSTSILTDPAQLPEQAS 906
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 31.2 bits (69), Expect = 3.9
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 46 GTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRS 105
GT + + + ++V +LK +L + ++ QL+EQ+ EI + +++
Sbjct: 1301 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTK-KSEEVFQLQEQINKQGLEI-ESLKT 1358
Query: 106 ALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLA 160
AE + L Q LE + + HL QP +D+L +IS+ EE +L+
Sbjct: 1359 VSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLS 1412
>gi|145553976 zinc finger, CW type with coiled-coil domain 2 isoform
a [Homo sapiens]
Length = 937
Score = 31.2 bits (69), Expect = 3.9
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 103 IRSALKNAEESKQFLNQFL-EQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAY 161
+++ L+ +E KQ L + L E ETHL + + P DDL ++++ + H++Y
Sbjct: 842 LKAELERTKEEKQELKEKLKETETHLEMLQKAQVSYRTPEGDDLERALAKLTRLRIHVSY 901
Query: 162 L 162
L
Sbjct: 902 L 902
>gi|148664197 coiled-coil domain containing 40 [Homo sapiens]
Length = 1142
Score = 31.2 bits (69), Expect = 3.9
Identities = 50/208 (24%), Positives = 92/208 (44%), Gaps = 28/208 (13%)
Query: 35 TVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIE-------QRTVSKMQ 87
T+LI KQ N L VS +EVG +K+L KLI+ Q V+ ++
Sbjct: 720 TILIERKQGLINFLNKQLERMVSELGGEEVGPLELEIKRLSKLIDEHDGKAVQAQVTWLR 779
Query: 88 LEEQVLTISSEIPKRIRS------ALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPW 141
L+++++ ++ E +++ S L E+ K + +EQE I H+
Sbjct: 780 LQQEMVKVTQEQEEQLASLDASKKELHIMEQKKLRVESKIEQEKKEQKEIEHHMKDLDND 839
Query: 142 MDDLGTMISQ----IEEIERH-----LAYLKWISQIEELSDNIQQYLMTNNVPEAASTLV 192
+ L ++++ EE+E++ +++ + E + +Q L N + E +TL+
Sbjct: 840 LKKLNMLMNKNRCSSEELEQNNRVTENEFVRSLKASERETIKMQDKL--NQLSEEKATLL 897
Query: 193 SM---AELDIKLQESSCTHLLGFMRATV 217
+ AE I L E L MR++V
Sbjct: 898 NQLVEAEHQIMLWEKK-IQLAKEMRSSV 924
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,246,254
Number of Sequences: 37866
Number of extensions: 1145864
Number of successful extensions: 3671
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 3631
Number of HSP's gapped (non-prelim): 100
length of query: 792
length of database: 18,247,518
effective HSP length: 110
effective length of query: 682
effective length of database: 14,082,258
effective search space: 9604099956
effective search space used: 9604099956
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.