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Search of human proteins with 62865869
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62865869 family with sequence similarity 13, member A1
isoform b [Homo sapiens]
(697 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865869 family with sequence similarity 13, member A1 isofor... 1389 0.0
gi|56119110 family with sequence similarity 13, member A1 isofor... 1370 0.0
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 494 e-139
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 439 e-123
gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] 427 e-119
gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens] 287 3e-77
gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapi... 287 3e-77
gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens] 144 2e-34
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 52 1e-06
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 48 3e-05
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 48 3e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 48 3e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 48 3e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 48 3e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 48 3e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 46 1e-04
gi|56549111 optineurin [Homo sapiens] 46 1e-04
gi|56549109 optineurin [Homo sapiens] 46 1e-04
gi|20149572 optineurin [Homo sapiens] 46 1e-04
gi|56549107 optineurin [Homo sapiens] 46 1e-04
gi|217330641 IWS1 homolog [Homo sapiens] 46 1e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 45 2e-04
gi|42794779 myosin 18A isoform b [Homo sapiens] 45 2e-04
gi|28416946 myosin 18A isoform a [Homo sapiens] 45 2e-04
gi|148746195 trichohyalin [Homo sapiens] 45 3e-04
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 45 3e-04
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 44 4e-04
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens] 44 4e-04
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 44 7e-04
gi|38044112 restin isoform b [Homo sapiens] 43 9e-04
>gi|62865869 family with sequence similarity 13, member A1 isoform b
[Homo sapiens]
Length = 697
Score = 1389 bits (3595), Expect = 0.0
Identities = 697/697 (100%), Positives = 697/697 (100%)
Query: 1 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG 60
MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG
Sbjct: 1 MACEIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGG 60
Query: 61 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT 120
QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT
Sbjct: 61 QSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT 120
Query: 121 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE 180
QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE
Sbjct: 121 QEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFE 180
Query: 181 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT 240
WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT
Sbjct: 181 WMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLT 240
Query: 241 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS 300
ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS
Sbjct: 241 ALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS 300
Query: 301 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF 360
RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF
Sbjct: 301 RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRF 360
Query: 361 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF 420
EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF
Sbjct: 361 EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSF 420
Query: 421 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV 480
GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV
Sbjct: 421 GSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKV 480
Query: 481 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLL 540
ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLL
Sbjct: 481 ALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLL 540
Query: 541 QPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPM 600
QPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPM
Sbjct: 541 QPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPM 600
Query: 601 DDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQK 660
DDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQK
Sbjct: 601 DDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQK 660
Query: 661 EDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 697
EDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM
Sbjct: 661 EDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 697
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 1370 bits (3547), Expect = 0.0
Identities = 688/688 (100%), Positives = 688/688 (100%)
Query: 10 SSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESG 69
SSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESG
Sbjct: 336 SSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESG 395
Query: 70 TLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKN 129
TLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKN
Sbjct: 396 TLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKN 455
Query: 130 TFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGN 189
TFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGN
Sbjct: 456 TFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGN 515
Query: 190 EKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWE 249
EKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWE
Sbjct: 516 EKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWE 575
Query: 250 EPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEV 309
EPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEV
Sbjct: 576 EPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEV 635
Query: 310 PPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPS 369
PPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPS
Sbjct: 636 PPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPS 695
Query: 370 HSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDE 429
HSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDE
Sbjct: 696 HSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDE 755
Query: 430 KKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYY 489
KKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYY
Sbjct: 756 KKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYY 815
Query: 490 ESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETA 549
ESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETA
Sbjct: 816 ESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETA 875
Query: 550 SFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCS 609
SFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCS
Sbjct: 876 SFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCS 935
Query: 610 QDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEE 669
QDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEE
Sbjct: 936 QDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEE 995
Query: 670 YSEYKHIKAKLRLLEVLISKRDTDSKSM 697
YSEYKHIKAKLRLLEVLISKRDTDSKSM
Sbjct: 996 YSEYKHIKAKLRLLEVLISKRDTDSKSM 1023
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 494 bits (1271), Expect = e-139
Identities = 314/710 (44%), Positives = 429/710 (60%), Gaps = 73/710 (10%)
Query: 4 EIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSS 63
E++ L+ ++ S S H+ +S + A+ ++LERTIR+AVEQHLFD+ QSS
Sbjct: 263 EVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDL-----QSS 317
Query: 64 EDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEV 123
D + L S + E H +G N+ + + D I+N E
Sbjct: 318 IDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID-------IADDIINASES 362
Query: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMS 183
+ + SKP +ST L QD + E+ +T+S E S
Sbjct: 363 NR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVGIL----LEPCS 403
Query: 184 DERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQRNQDAGDQEESF 230
D +G+ +DG + F+S + KI + + ++++ Q G Q E+
Sbjct: 404 D--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAA 461
Query: 231 VSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPML 290
+P DL + D WEEP PAF SWQ E+S+S EA LSPQAGR+ L+ED P+L
Sbjct: 462 CVSIPHLDLKNVSDGDKWEEPFPAFKSWQ-EDSESGEAQLSPQAGRMNHHPLEEDCPPVL 520
Query: 291 SPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLK 350
S R +GQS+++L D E S + SF R R SS S D+++ED TP QL +++Q
Sbjct: 521 SHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ--- 577
Query: 351 KKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMR 410
KKIR+FE++FE E+ +PS+SD AANP+VLKW +L K R+Q+K++K K S+ + P+ R
Sbjct: 578 KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTR 637
Query: 411 QRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEATLESIQRKLQEKRAESSRPEDI 467
RSNTLPKSFGS L+ EDE+ ++ ++ K KPS EATLE I ++L+EKR E PEDI
Sbjct: 638 PRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDI 697
Query: 468 KDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPI 527
K MTKD + EK +LQK+LLYYES HGRPVTK ER ++KPLYDRYRLVKQ+L+RA+ P+
Sbjct: 698 KKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPV 757
Query: 528 IGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLD 587
+GSPS+KRR +LQPIIEGETA FF+EIKEEE ED N+ + LKT + L+
Sbjct: 758 LGSPSTKRRGQMLQPIIEGETAHFFEEIKEEE---EDGVNLSSELGDMLKTAVQVQSSLE 814
Query: 588 QFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFE 647
E D ++ K + D LS+ AAS+PELLE L + R EKK++RK LR+FE
Sbjct: 815 NSESDV--------EENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFE 866
Query: 648 DNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 697
+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEVLISK+D+ SKS+
Sbjct: 867 EAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS-SKSI 915
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 439 bits (1130), Expect = e-123
Identities = 295/710 (41%), Positives = 407/710 (57%), Gaps = 101/710 (14%)
Query: 4 EIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSS 63
E++ L+ ++ S S H+ +S + A+ ++LERTIR+AVEQHLFD+ QSS
Sbjct: 263 EVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDL-----QSS 317
Query: 64 EDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEV 123
D + L S + E H +G N+ + + D I+N E
Sbjct: 318 IDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID-------IADDIINASES 362
Query: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMS 183
+ + SKP +ST L QD + E+ +T+S E S
Sbjct: 363 NR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVGIL----LEPCS 403
Query: 184 DERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQRNQDAGDQEESF 230
D +G+ +DG + F+S + KI + + ++++ Q G Q E+
Sbjct: 404 D--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAA 461
Query: 231 VSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPML 290
+P DL + D WEEP PAF SWQ E+S+S EA LSPQAGR+ L+ED P+L
Sbjct: 462 CVSIPHLDLKNVSDGDKWEEPFPAFKSWQ-EDSESGEAQLSPQAGRMNHHPLEEDCPPVL 520
Query: 291 SPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLK 350
S R +GQS+++L D E S + SF R R SS S D+++ED TP QL +++Q
Sbjct: 521 SHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ--- 577
Query: 351 KKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMR 410
KKIR+FE++FE E+ +PS+SD AANP+VLKW +L K R+Q+K++K K S+ + P+ R
Sbjct: 578 KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTR 637
Query: 411 QRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEATLESIQRKLQEKRAESSRPEDI 467
RSNTLPKSFGS L+ EDE+ ++ ++ K KPS EATLE I ++L+EKR E PEDI
Sbjct: 638 PRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDI 697
Query: 468 KDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPI 527
K VTK ER ++KPLYDRYRLVKQ+L+RA+ P+
Sbjct: 698 K----------------------------VTKEERHIVKPLYDRYRLVKQMLTRASITPV 729
Query: 528 IGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLD 587
+GSPS+KRR +LQPIIEGETA FF+EIKEEEE D N+ + LKT + L+
Sbjct: 730 LGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEE---DGVNLSSELGDMLKTAVQVQSSLE 786
Query: 588 QFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFE 647
E D + + K + D LS+ AAS+PELLE L + R EKK++RK LR+FE
Sbjct: 787 NSESDVE--------ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFE 838
Query: 648 DNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 697
+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEVLISK+D+ SKS+
Sbjct: 839 EAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS-SKSI 887
>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
Length = 791
Score = 427 bits (1097), Expect = e-119
Identities = 295/732 (40%), Positives = 407/732 (55%), Gaps = 123/732 (16%)
Query: 4 EIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSS 63
E++ L+ ++ S S H+ +S + A+ ++LERTIR+AVEQHLFD+ QSS
Sbjct: 145 EVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDL-----QSS 199
Query: 64 EDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEV 123
D + L S + E H +G N+ + + D I+N E
Sbjct: 200 IDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID-------IADDIINASES 244
Query: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMS 183
+ + SKP +ST L QD + E+ +T+S E S
Sbjct: 245 NR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVGIL----LEPCS 285
Query: 184 DERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQRNQDAGDQEESF 230
D +G+ +DG + F+S + KI + + ++++ Q G Q E+
Sbjct: 286 D--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAA 343
Query: 231 VSEVPQSDLTALCDEKNWE----------------------EPIPAFSSWQRENSDSDEA 268
+P DL + D WE EP PAF SWQ E+S+S EA
Sbjct: 344 CVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQ-EDSESGEA 402
Query: 269 HLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLG 328
LSPQAGR+ L+ED P+LS R +GQS+++L D E S + SF R R SS
Sbjct: 403 QLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS 462
Query: 329 SYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAK 388
S D+++ED TP QL +++Q KKIR+FE++FE E+ +PS+SD AANP+VLKW +L K
Sbjct: 463 SKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTK 519
Query: 389 FRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEA 445
R+Q+K++K K S+ + P+ R RSNTLPKSFGS L+ EDE+ ++ ++ K KPS EA
Sbjct: 520 LRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEA 579
Query: 446 TLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVM 505
TLE I ++L+EKR E PEDIK VTK ER ++
Sbjct: 580 TLELILKRLKEKRIERCLPEDIK----------------------------VTKEERHIV 611
Query: 506 KPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDD 565
KPLYDRYRLVKQ+L+RA+ P++GSPS+KRR +LQPIIEGETA FF+EIKEEEE D
Sbjct: 612 KPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEE---DG 668
Query: 566 SNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPEL 625
N+ + LKT + L+ E D + + K + D LS+ AAS+PEL
Sbjct: 669 VNLSSELGDMLKTAVQVQSSLENSESDVE--------ENQEKLALDLRLSSSRAASMPEL 720
Query: 626 LEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEV 685
LE L + R EKK++RK LR+FE+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEV
Sbjct: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
Query: 686 LISKRDTDSKSM 697
LISK+D+ SKS+
Sbjct: 781 LISKQDS-SKSI 791
>gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens]
Length = 585
Score = 287 bits (734), Expect = 3e-77
Identities = 185/478 (38%), Positives = 255/478 (53%), Gaps = 59/478 (12%)
Query: 214 DTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ 273
+T+Q N++ Q P S + L D + +P P Q E + E S
Sbjct: 162 ETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVG 221
Query: 274 AGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE 333
RL+ + D D+ P+LSPR + QS+++ D E PSPP++ FM RSSS S D
Sbjct: 222 TSRLLYHITDGDN-PLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDG 280
Query: 334 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 393
+E T QLT+ IQSLK+KIRKFE++FE+EKKYRPSH DK +NPEVLKW NDLAK R+QL
Sbjct: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 340
Query: 394 KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRK 453
KE KLK+SEE + N L + + K E S E T ++
Sbjct: 341 KELKLKLSEEQGSAPKGPPRNLLCE---QPTVPRENGKPEAAGPEPSSSGEETPDAALTC 397
Query: 454 LQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYR 513
L+E+R + ED K VTK ++ ++KPLYDRYR
Sbjct: 398 LKERREQLPPQEDSK----------------------------VTKQDKNLIKPLYDRYR 429
Query: 514 LVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFM 573
++KQILS +P L P I+ E S ++ +GS+ S P
Sbjct: 430 IIKQILS----------------TPSLIPTIQEEEDS----DEDRPQGSQQPSLADPASH 469
Query: 574 VTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMR 633
+ + + + ++ + + + D+ +SNLH A++P LL+HL+E R
Sbjct: 470 LPVGDHLT-------YSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETR 522
Query: 634 EEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 691
+KKR+RK LR+FE+ FF+Q GR+ QKEDR PMA+EY EYKHIKAKLRLLEVLISK+D
Sbjct: 523 ADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQD 580
Score = 29.6 bits (65), Expect = 9.9
Identities = 51/240 (21%), Positives = 89/240 (37%), Gaps = 49/240 (20%)
Query: 174 TGPDDFEWMSDERKG-----------NEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQD 222
+ P+ +WM+D KG +E+ G + P + E P++ + + +
Sbjct: 322 SNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKG--PPRNLLCEQPTVP-RENGKPEA 378
Query: 223 AGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLL 282
AG + S E P + LT L K E +P + D + R+I+Q+L
Sbjct: 379 AGPEPSSSGEETPDAALTCL---KERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQIL 435
Query: 283 DEDSDPMLSPRFYAYGQSRQYLDDTEVPPS--PPNSH-------SFMRRRSSSLGSYDDE 333
S P L P S + PS P SH ++ DE
Sbjct: 436 ---STPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDE 492
Query: 334 QEDLTPAQLT----------------RRIQSLKKKIRK----FEDRFEEEKKYRPSHSDK 373
++++ P L+ R ++ KK++RK FE++F ++ P D+
Sbjct: 493 KKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDR 552
>gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo
sapiens]
Length = 502
Score = 287 bits (734), Expect = 3e-77
Identities = 185/478 (38%), Positives = 255/478 (53%), Gaps = 59/478 (12%)
Query: 214 DTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ 273
+T+Q N++ Q P S + L D + +P P Q E + E S
Sbjct: 79 ETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVG 138
Query: 274 AGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE 333
RL+ + D D+ P+LSPR + QS+++ D E PSPP++ FM RSSS S D
Sbjct: 139 TSRLLYHITDGDN-PLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDG 197
Query: 334 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 393
+E T QLT+ IQSLK+KIRKFE++FE+EKKYRPSH DK +NPEVLKW NDLAK R+QL
Sbjct: 198 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 257
Query: 394 KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRK 453
KE KLK+SEE + N L + + K E S E T ++
Sbjct: 258 KELKLKLSEEQGSAPKGPPRNLLCE---QPTVPRENGKPEAAGPEPSSSGEETPDAALTC 314
Query: 454 LQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYR 513
L+E+R + ED K VTK ++ ++KPLYDRYR
Sbjct: 315 LKERREQLPPQEDSK----------------------------VTKQDKNLIKPLYDRYR 346
Query: 514 LVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFM 573
++KQILS +P L P I+ E S ++ +GS+ S P
Sbjct: 347 IIKQILS----------------TPSLIPTIQEEEDS----DEDRPQGSQQPSLADPASH 386
Query: 574 VTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMR 633
+ + + + ++ + + + D+ +SNLH A++P LL+HL+E R
Sbjct: 387 LPVGDHLT-------YSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETR 439
Query: 634 EEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 691
+KKR+RK LR+FE+ FF+Q GR+ QKEDR PMA+EY EYKHIKAKLRLLEVLISK+D
Sbjct: 440 ADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQD 497
Score = 29.6 bits (65), Expect = 9.9
Identities = 51/240 (21%), Positives = 89/240 (37%), Gaps = 49/240 (20%)
Query: 174 TGPDDFEWMSDERKG-----------NEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQD 222
+ P+ +WM+D KG +E+ G + P + E P++ + + +
Sbjct: 239 SNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKG--PPRNLLCEQPTVP-RENGKPEA 295
Query: 223 AGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLL 282
AG + S E P + LT L K E +P + D + R+I+Q+L
Sbjct: 296 AGPEPSSSGEETPDAALTCL---KERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQIL 352
Query: 283 DEDSDPMLSPRFYAYGQSRQYLDDTEVPPS--PPNSH-------SFMRRRSSSLGSYDDE 333
S P L P S + PS P SH ++ DE
Sbjct: 353 ---STPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDE 409
Query: 334 QEDLTPAQLT----------------RRIQSLKKKIRK----FEDRFEEEKKYRPSHSDK 373
++++ P L+ R ++ KK++RK FE++F ++ P D+
Sbjct: 410 KKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDR 469
>gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]
Length = 487
Score = 144 bits (364), Expect = 2e-34
Identities = 90/232 (38%), Positives = 132/232 (56%), Gaps = 28/232 (12%)
Query: 460 ESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQIL 519
+ P+ I +TK I + K ++K +E VTK ++ ++KPLYDRYR++KQIL
Sbjct: 279 DGKEPQTITQLTK-HIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQIL 337
Query: 520 SRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTD 579
S +P L P I+ E S ++ +GS+ S P + +
Sbjct: 338 S----------------TPSLIPTIQEEEDSD----EDRPQGSQQPSLADPASHLPVGDH 377
Query: 580 FSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRI 639
+ + ++ + + + D+ +SNLH A++P LL+HL+E R +KKR+
Sbjct: 378 LT-------YSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRL 430
Query: 640 RKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 691
RK LR+FE+ FF+Q GR+ QKEDR PMA+EY EYKHIKAKLRLLEVLISK+D
Sbjct: 431 RKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQD 482
Score = 116 bits (291), Expect = 6e-26
Identities = 103/330 (31%), Positives = 150/330 (45%), Gaps = 50/330 (15%)
Query: 214 DTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ 273
+T+Q N++ Q P S + L D + +P P Q E + E S
Sbjct: 162 ETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVG 221
Query: 274 AGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE 333
RL+ + D D+ P+LSPR + QS+++ D E PSPP++ FM RSSS S D
Sbjct: 222 TSRLLYHITDGDN-PLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDG 280
Query: 334 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 393
+E T QLT+ IQSLK+KIRKFE++FE+EKKYR + DK ++K D + +Q+
Sbjct: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDK----NLIKPLYDRYRIIKQI 336
Query: 394 KESKLKI--------SEEDLTPRMRQRSNTLPKS---FGSQLEKEDE----------KKQ 432
+ I S+ED +Q S P S G L +E +K+
Sbjct: 337 LSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKK 396
Query: 433 ELVDKAIKPS--VEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYE 490
E+ A+ S EAT+ + L+E RA+ R L+KAL +E
Sbjct: 397 EVKPPALSMSNLHEATMPVLLDHLRETRADKKR------------------LRKALREFE 438
Query: 491 SIH----GRPVTKNERQVMKPLYDRYRLVK 516
GR K +R M Y Y+ +K
Sbjct: 439 EQFFKQTGRSPQKEDRIPMADEYYEYKHIK 468
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 52.4 bits (124), Expect = 1e-06
Identities = 85/450 (18%), Positives = 181/450 (40%), Gaps = 54/450 (12%)
Query: 40 LERTIRSAVEQHLFDVNNSGGQS-SEDSESGTLSA-----SSATSARQRR------RQSK 87
++R + EQ + D+NN+G +S SE+ + L S TS + ++ ++ +
Sbjct: 139 IQRELAKRAEQ-IEDINNTGTESASEEGDDSLLITVVPVKSYKTSGKMKKNFEDLEKERE 197
Query: 88 EQDEVRHGRDKGLINKENTPSGFNH------LDDCILNTQEVEKVHKNTFGCAGERSKPK 141
E++ +++ DK + +E PS +DD I + + E + E + +
Sbjct: 198 EKERIKYEEDKRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQ 257
Query: 142 RQKSSTKLSE-------------LHDNQDGLVNMESLNSTRSHERTGPD------DFEWM 182
RQ++ K +E + + +VN + N + G FE M
Sbjct: 258 RQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEENQDTAKIFKGYRPGKLKLSFEEM 317
Query: 183 SDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTAL 242
+R+ +EK E +I+E + + +RN D + Q LT
Sbjct: 318 ERQRREDEKRKAE----EEARRRIEEEKK-AFAEARRNMVVDDDSPEMYKTISQEFLTPG 372
Query: 243 CDEKNWEEPIPAFSSWQRENSDSDEAH---LSPQAGRLIRQLLDEDSDPMLSPRFYAYGQ 299
E N+EE + ++ ++ + H + Q +RQ + E+ + + +G
Sbjct: 373 KLEINFEELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEENET-----FGL 427
Query: 300 SRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE--QEDLTPAQLTRRIQSLKKKIRKFE 357
SR+Y + ++ S ++ + +G ++ Q+ + + RR L+ K R+ E
Sbjct: 428 SREYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDLEIKEREAE 487
Query: 358 DRFEEEK-KYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTL 416
+ EE+ RP+ +A + + + +E + + EE RM+ +
Sbjct: 488 NFHEEDDVDVRPARKSEAPFTHKVNMKARFEQMAKAREEEEQRRIEEQKLLRMQFEQREI 547
Query: 417 PKSFGSQLEKEDEKKQELVDKAIKPSVEAT 446
+ + E+E+E++ +++ + E T
Sbjct: 548 DAALQKKREEEEEEEGSIMNGSTAEDEEQT 577
Score = 40.8 bits (94), Expect = 0.004
Identities = 85/479 (17%), Positives = 178/479 (37%), Gaps = 79/479 (16%)
Query: 11 SQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGT 70
+ +DE +S A+VP+++ + G E + EQ + +E+
Sbjct: 79 ASDDEEDVSSKVEKAYVPKLTG-TVKGRFAEMEKQRQEEQR---------KRTEEERKRR 128
Query: 71 LSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNT-------QEV 123
+ + +R +K +++ IN T S DD +L T +
Sbjct: 129 IEQDMLEKRKIQRELAKRAEQIED------INNTGTESASEEGDDSLLITVVPVKSYKTS 182
Query: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQD---------GLVNMESLNSTRSHERT 174
K+ KN ER + +R K ++ Q LV + + S E
Sbjct: 183 GKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKESL 242
Query: 175 GPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDT--KQQRNQDAGDQEESFVS 232
P + +E + ++ Q E +++E + +Q N+D +Q+ + +
Sbjct: 243 SPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEENQDTAKIF 302
Query: 233 EVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSP 292
+ + L +F +R+ + ++ +A R I +
Sbjct: 303 KGYRPGKLKL-----------SFEEMERQRREDEKRKAEEEARRRIEE----------EK 341
Query: 293 RFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQS-LKK 351
+ +A + +DD P + + QE LTP +L + LK+
Sbjct: 342 KAFAEARRNMVVDDDS-----PEMYKTI------------SQEFLTPGKLEINFEELLKQ 384
Query: 352 KIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQ 411
K+ + + R EEE+K H + E + ++ + + + L E+L ++++
Sbjct: 385 KMEEEKRRTEEERK----HKLEMEKQEFEQLRQEMGEEEEENETFGLSREYEELI-KLKR 439
Query: 412 RSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDM 470
+ K+ S+ EK + ++ + K I+ A +I +++E+ AE+ ED D+
Sbjct: 440 SGSIQAKNLKSKFEKIGQLSEKEIQKKIEEE-RARRRAIDLEIKEREAENFHEEDDVDV 497
Score = 33.1 bits (74), Expect = 0.89
Identities = 67/367 (18%), Positives = 138/367 (37%), Gaps = 99/367 (26%)
Query: 355 KFE--DRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQR 412
KFE R EE+ R S +K E + + ++++KE EED++ +
Sbjct: 34 KFEAMQRAREERNQRRSRDEKQRRKEQYIREREWNRRKQEIKEMLASDDEEDVSSK---- 89
Query: 413 SNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTK 472
V+KA P + T++ +++++R E R
Sbjct: 90 ----------------------VEKAYVPKLTGTVKGRFAEMEKQRQEEQRK-------- 119
Query: 473 DQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPS 532
R + +R++ + + ++ ++ +++ RA I I +
Sbjct: 120 ----------------------RTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTG 157
Query: 533 SKRRS------------PLLQPIIEGETASFFKEIKEEEEGS-----EDDSNVK-PDFMV 574
++ S P+ G+ F+++++E E E+D ++ +
Sbjct: 158 TESASEEGDDSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRP 217
Query: 575 TLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMR- 633
+LK A+C MDD+I S+ +++ + EL QE R
Sbjct: 218 SLK---EAKC-----------LSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRK 263
Query: 634 -----EEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLIS 688
E +KR+ ++ R FE+ R+ N + E+ A+ + Y+ K KL E+
Sbjct: 264 KQAEEEARKRLEEEKRAFEE--ARRQMVN-EDEENQDTAKIFKGYRPGKLKLSFEEMERQ 320
Query: 689 KRDTDSK 695
+R+ + +
Sbjct: 321 RREDEKR 327
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 48.1 bits (113), Expect = 3e-05
Identities = 59/333 (17%), Positives = 151/333 (45%), Gaps = 22/333 (6%)
Query: 322 RRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLK 381
++ +L S +++ + ++++ Q ++ ++ E + D+ + + +
Sbjct: 1084 QQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISR 1143
Query: 382 WTNDLAKFRRQL-KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIK 440
+ + +L K + L ++ ++++ L S+L + +K E + + +
Sbjct: 1144 HEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQ-E 1202
Query: 441 PSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKN 500
EA ++++++ Q + SS+ +D + + + + A+Q AL + K
Sbjct: 1203 EKYEAIIQNLEKDRQ--KLVSSQEQDREQLIQKLNCEKDEAIQTALKEF---------KL 1251
Query: 501 ERQVM-KPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEE 559
ER+V+ K L ++ + ++ ++++ I SS + L + + E E A F ++++E+E
Sbjct: 1252 EREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQE-EKAKFLEQLEEQE 1310
Query: 560 EG-SEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLH 618
+ +E+ NV+ + +T+F+ L + + + I+ + DK+ S Q +L
Sbjct: 1311 KRKNEEMQNVRTSLIAEQQTNFNT--VLTREKMRKENIINDLSDKLKSTMQQQERDKDL- 1367
Query: 619 AASIPELLEHLQEMREEKKRIRKKLRDFEDNFF 651
I L E + EEKK++ +++ + F
Sbjct: 1368 ---IESLSEDRARLLEEKKKLEEEVSKLRSSSF 1397
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 48.1 bits (113), Expect = 3e-05
Identities = 59/333 (17%), Positives = 151/333 (45%), Gaps = 22/333 (6%)
Query: 322 RRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLK 381
++ +L S +++ + ++++ Q ++ ++ E + D+ + + +
Sbjct: 1084 QQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISR 1143
Query: 382 WTNDLAKFRRQL-KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIK 440
+ + +L K + L ++ ++++ L S+L + +K E + + +
Sbjct: 1144 HEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQ-E 1202
Query: 441 PSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKN 500
EA ++++++ Q + SS+ +D + + + + A+Q AL + K
Sbjct: 1203 EKYEAIIQNLEKDRQ--KLVSSQEQDREQLIQKLNCEKDEAIQTALKEF---------KL 1251
Query: 501 ERQVM-KPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEE 559
ER+V+ K L ++ + ++ ++++ I SS + L + + E E A F ++++E+E
Sbjct: 1252 EREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQE-EKAKFLEQLEEQE 1310
Query: 560 EG-SEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLH 618
+ +E+ NV+ + +T+F+ L + + + I+ + DK+ S Q +L
Sbjct: 1311 KRKNEEMQNVRTSLIAEQQTNFNT--VLTREKMRKENIINDLSDKLKSTMQQQERDKDL- 1367
Query: 619 AASIPELLEHLQEMREEKKRIRKKLRDFEDNFF 651
I L E + EEKK++ +++ + F
Sbjct: 1368 ---IESLSEDRARLLEEKKKLEEEVSKLRSSSF 1397
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 48.1 bits (113), Expect = 3e-05
Identities = 94/377 (24%), Positives = 152/377 (40%), Gaps = 55/377 (14%)
Query: 333 EQEDLTPAQ--LTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390
E EDL ++ + + + L+K R E + EE K D+ L+ T D AK R
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE------LQATED-AKLR 1564
Query: 391 RQLKESKLKIS-EEDLTPRMRQ----RSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEA 445
++ LK E DL R Q R + + E EDE+KQ + A K +E
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1624
Query: 446 TLESIQRKLQEKRAESSRPEDIKDMTK--DQIANEKVALQKALLYYESIHGRPVTKNER- 502
L+ ++ LQ A R E IK + K Q+ + + L+ A + I +NE+
Sbjct: 1625 DLKDLE--LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA-TAKENEKK 1681
Query: 503 ---------QVMKPLYDRYRLVKQI-LSRANTIPIIGSPSSKRRSPLLQP---IIEGETA 549
Q+ + L R KQ L + + S S R + LQ +E A
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA--LQDEKRRLEARIA 1739
Query: 550 SFFKEIKEEE--------------EGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADG 595
+E++EE+ + +E SN T + + SAR L++ +
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
Query: 596 FISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNG 655
+ M+ + SK A I +L E +++ EK+ K L+ +D ++
Sbjct: 1800 KLHEMEGAVKSKFKSTIAALE---AKIAQLEEQVEQEAREKQAATKSLKQ-KDKKLKE-- 1853
Query: 656 RNVQKEDRTPMAEEYSE 672
+Q ED MAE+Y E
Sbjct: 1854 ILLQVEDERKMAEQYKE 1870
Score = 37.0 bits (84), Expect = 0.062
Identities = 90/496 (18%), Positives = 180/496 (36%), Gaps = 39/496 (7%)
Query: 31 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 90
S +S L++ +S E G S + L A A Q ++ +E
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 91 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 150
D + K N L+ I + QE + A ++ + ++ +
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153
Query: 151 ELHDNQDGLVNMESLNSTRSHERTGPD---DFEWMSDERKGNEKDGGHTQHFESPTMKIQ 207
EL D D + L + R E T D E S E + E H Q E T +++
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE 1213
Query: 208 EHPSLSDTKQQRNQDAGDQEESFVSEVP---QSDLTALCDEKNWEEPIPAFSSWQRENSD 264
+ + Q + E+ Q+ +K E + S + + +
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS-KCSDGE 1272
Query: 265 SDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRS 324
A L+ + +L ++ E ML+ A G++ + D + S
Sbjct: 1273 RARAELNDKVHKLQNEV--ESVTGMLNE---AEGKAIKLAKD-------------VASLS 1314
Query: 325 SSLGSYDD--EQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVL-- 380
S L + ++E ++ +++ L+++ +D+ +EE + + + + +
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 381 ---KWTNDLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQELV 435
K D A L+E K + +E +LT + +++ K ++ + E +V
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 436 DKAIKPSVEATLESIQRKLQEKRAE----SSRPEDIKDMTKDQI-ANEKVALQKALLYYE 490
D + + + LE QRK + AE SS+ D +D + + E AL A E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 491 SIHGRPVTKNERQVMK 506
++ + + +++K
Sbjct: 1495 ALEAKEELERTNKMLK 1510
Score = 36.2 bits (82), Expect = 0.11
Identities = 69/370 (18%), Positives = 139/370 (37%), Gaps = 48/370 (12%)
Query: 346 IQSLKKKIRKFEDRFEEEKKYRPSHSDK--AANPEVLKWTNDLAKFRRQLKESKLKISEE 403
+ +L+KK RKF+ EEK ++D+ A E + R L+E+ L+ EE
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA-LEAKEE 1501
Query: 404 DLTPRMRQRSNTLPKSFGSQL--EKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAES 461
+R+N + K+ L K+D K + K ++E +E ++ +L+E E
Sbjct: 1502 ------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Query: 462 SRPEDIK------------DMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLY 509
ED K +D A ++ +K +H + + + L
Sbjct: 1556 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 510 DRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPI--IEGETASFFKEIKEEEEGSEDDSN 567
+ K++ + + + K R ++ + ++ + F +E+ E+ S D+
Sbjct: 1616 AAAK--KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-EDARASRDEI- 1671
Query: 568 VKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLH-AASIPELL 626
F + + A+ +AD D + + L A + L
Sbjct: 1672 ----FATAKENEKKAKSL------EADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 627 EHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVL 686
+++EK+R+ ++ E+ + G DR A + +E +L L
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE--------QLSNEL 1773
Query: 687 ISKRDTDSKS 696
++R T K+
Sbjct: 1774 ATERSTAQKN 1783
Score = 32.7 bits (73), Expect = 1.2
Identities = 97/569 (17%), Positives = 226/569 (39%), Gaps = 76/569 (13%)
Query: 132 GCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGP-----DDFEWMSDER 186
G ++ KRQ+ T + + N + + + R + P E M +
Sbjct: 799 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
Query: 187 KGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEK 246
+K Q E+ ++++ S ++ Q+ E +E + + ++
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918
Query: 247 NWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSD---------PMLSPRFYAY 297
EE + + E D + L + ++ +Q+LD + + + A
Sbjct: 919 ELEEILHEMEARLEEEEDRGQ-QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
Query: 298 GQSRQYLDDTEVPPSPPNSHSFMRRR--------SSSLGSYDDEQEDLTPAQLTRR--IQ 347
+ ++ D+ V N S R+ +++L +++ ++LT + I
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 348 SLKKKIRKFE-DRFEEEKKYRPSHSDKAA-NPEVLKWTNDLAKFRRQL--KESKLKISEE 403
L+ +++K E R E EK R D + + ++ +A+ + QL KE +L+ +
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 404 DLTPRMRQRSNTLPK-----SFGSQLEKEDEKKQELVDKAIKPSVEA--TLESIQRKLQE 456
L + Q++N L K S L+++ + ++ +KA K + LE+++ +L++
Sbjct: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
Query: 457 KRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVK 516
++ ++++ + ++ K AL + +E+ + + + Q ++ L ++ K
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFK 1216
Query: 517 QILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTL 576
+ ++AN K + L E E A E++ + ++ + K +
Sbjct: 1217 R--AKANL--------DKNKQTL-----EKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 577 KTDFSARCFLDQFEDDADGFISPMDDKI---PSKCSQDTGLSN----------LHAASIP 623
+ + ++C D + + ++DK+ ++ TG+ N AS+
Sbjct: 1262 Q-ELQSKC------SDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
Query: 624 ELLEHLQEMREEKKR----IRKKLRDFED 648
L+ QE+ +E+ R + KLR E+
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 48.1 bits (113), Expect = 3e-05
Identities = 94/377 (24%), Positives = 152/377 (40%), Gaps = 55/377 (14%)
Query: 333 EQEDLTPAQ--LTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390
E EDL ++ + + + L+K R E + EE K D+ L+ T D AK R
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE------LQATED-AKLR 1571
Query: 391 RQLKESKLKIS-EEDLTPRMRQ----RSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEA 445
++ LK E DL R Q R + + E EDE+KQ + A K +E
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1631
Query: 446 TLESIQRKLQEKRAESSRPEDIKDMTK--DQIANEKVALQKALLYYESIHGRPVTKNER- 502
L+ ++ LQ A R E IK + K Q+ + + L+ A + I +NE+
Sbjct: 1632 DLKDLE--LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA-TAKENEKK 1688
Query: 503 ---------QVMKPLYDRYRLVKQI-LSRANTIPIIGSPSSKRRSPLLQP---IIEGETA 549
Q+ + L R KQ L + + S S R + LQ +E A
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA--LQDEKRRLEARIA 1746
Query: 550 SFFKEIKEEE--------------EGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADG 595
+E++EE+ + +E SN T + + SAR L++ +
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1806
Query: 596 FISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNG 655
+ M+ + SK A I +L E +++ EK+ K L+ +D ++
Sbjct: 1807 KLHEMEGAVKSKFKSTIAALE---AKIAQLEEQVEQEAREKQAATKSLKQ-KDKKLKE-- 1860
Query: 656 RNVQKEDRTPMAEEYSE 672
+Q ED MAE+Y E
Sbjct: 1861 ILLQVEDERKMAEQYKE 1877
Score = 37.0 bits (84), Expect = 0.062
Identities = 90/496 (18%), Positives = 180/496 (36%), Gaps = 39/496 (7%)
Query: 31 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 90
S +S L++ +S E G S + L A A Q ++ +E
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1100
Query: 91 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 150
D + K N L+ I + QE + A ++ + ++ +
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160
Query: 151 ELHDNQDGLVNMESLNSTRSHERTGPD---DFEWMSDERKGNEKDGGHTQHFESPTMKIQ 207
EL D D + L + R E T D E S E + E H Q E T +++
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE 1220
Query: 208 EHPSLSDTKQQRNQDAGDQEESFVSEVP---QSDLTALCDEKNWEEPIPAFSSWQRENSD 264
+ + Q + E+ Q+ +K E + S + + +
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS-KCSDGE 1279
Query: 265 SDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRS 324
A L+ + +L ++ E ML+ A G++ + D + S
Sbjct: 1280 RARAELNDKVHKLQNEV--ESVTGMLNE---AEGKAIKLAKD-------------VASLS 1321
Query: 325 SSLGSYDD--EQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVL-- 380
S L + ++E ++ +++ L+++ +D+ +EE + + + + +
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 381 ---KWTNDLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQELV 435
K D A L+E K + +E +LT + +++ K ++ + E +V
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 436 DKAIKPSVEATLESIQRKLQEKRAE----SSRPEDIKDMTKDQI-ANEKVALQKALLYYE 490
D + + + LE QRK + AE SS+ D +D + + E AL A E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 491 SIHGRPVTKNERQVMK 506
++ + + +++K
Sbjct: 1502 ALEAKEELERTNKMLK 1517
Score = 36.2 bits (82), Expect = 0.11
Identities = 69/370 (18%), Positives = 139/370 (37%), Gaps = 48/370 (12%)
Query: 346 IQSLKKKIRKFEDRFEEEKKYRPSHSDK--AANPEVLKWTNDLAKFRRQLKESKLKISEE 403
+ +L+KK RKF+ EEK ++D+ A E + R L+E+ L+ EE
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA-LEAKEE 1508
Query: 404 DLTPRMRQRSNTLPKSFGSQL--EKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAES 461
+R+N + K+ L K+D K + K ++E +E ++ +L+E E
Sbjct: 1509 ------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Query: 462 SRPEDIK------------DMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLY 509
ED K +D A ++ +K +H + + + L
Sbjct: 1563 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1622
Query: 510 DRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPI--IEGETASFFKEIKEEEEGSEDDSN 567
+ K++ + + + K R ++ + ++ + F +E+ E+ S D+
Sbjct: 1623 AAAK--KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-EDARASRDEI- 1678
Query: 568 VKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLH-AASIPELL 626
F + + A+ +AD D + + L A + L
Sbjct: 1679 ----FATAKENEKKAKSL------EADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 627 EHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVL 686
+++EK+R+ ++ E+ + G DR A + +E +L L
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE--------QLSNEL 1780
Query: 687 ISKRDTDSKS 696
++R T K+
Sbjct: 1781 ATERSTAQKN 1790
Score = 32.7 bits (73), Expect = 1.2
Identities = 97/569 (17%), Positives = 226/569 (39%), Gaps = 76/569 (13%)
Query: 132 GCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGP-----DDFEWMSDER 186
G ++ KRQ+ T + + N + + + R + P E M +
Sbjct: 806 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865
Query: 187 KGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEK 246
+K Q E+ ++++ S ++ Q+ E +E + + ++
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 925
Query: 247 NWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSD---------PMLSPRFYAY 297
EE + + E D + L + ++ +Q+LD + + + A
Sbjct: 926 ELEEILHEMEARLEEEEDRGQ-QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984
Query: 298 GQSRQYLDDTEVPPSPPNSHSFMRRR--------SSSLGSYDDEQEDLTPAQLTRR--IQ 347
+ ++ D+ V N S R+ +++L +++ ++LT + I
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 348 SLKKKIRKFE-DRFEEEKKYRPSHSDKAA-NPEVLKWTNDLAKFRRQL--KESKLKISEE 403
L+ +++K E R E EK R D + + ++ +A+ + QL KE +L+ +
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 404 DLTPRMRQRSNTLPK-----SFGSQLEKEDEKKQELVDKAIKPSVEA--TLESIQRKLQE 456
L + Q++N L K S L+++ + ++ +KA K + LE+++ +L++
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 457 KRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVK 516
++ ++++ + ++ K AL + +E+ + + + Q ++ L ++ K
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 517 QILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTL 576
+ ++AN K + L E E A E++ + ++ + K +
Sbjct: 1224 R--AKANL--------DKNKQTL-----EKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 577 KTDFSARCFLDQFEDDADGFISPMDDKI---PSKCSQDTGLSN----------LHAASIP 623
+ + ++C D + + ++DK+ ++ TG+ N AS+
Sbjct: 1269 Q-ELQSKC------SDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1321
Query: 624 ELLEHLQEMREEKKR----IRKKLRDFED 648
L+ QE+ +E+ R + KLR E+
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEE 1350
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 48.1 bits (113), Expect = 3e-05
Identities = 94/377 (24%), Positives = 152/377 (40%), Gaps = 55/377 (14%)
Query: 333 EQEDLTPAQ--LTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390
E EDL ++ + + + L+K R E + EE K D+ L+ T D AK R
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE------LQATED-AKLR 1571
Query: 391 RQLKESKLKIS-EEDLTPRMRQ----RSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEA 445
++ LK E DL R Q R + + E EDE+KQ + A K +E
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1631
Query: 446 TLESIQRKLQEKRAESSRPEDIKDMTK--DQIANEKVALQKALLYYESIHGRPVTKNER- 502
L+ ++ LQ A R E IK + K Q+ + + L+ A + I +NE+
Sbjct: 1632 DLKDLE--LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA-TAKENEKK 1688
Query: 503 ---------QVMKPLYDRYRLVKQI-LSRANTIPIIGSPSSKRRSPLLQP---IIEGETA 549
Q+ + L R KQ L + + S S R + LQ +E A
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA--LQDEKRRLEARIA 1746
Query: 550 SFFKEIKEEE--------------EGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADG 595
+E++EE+ + +E SN T + + SAR L++ +
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1806
Query: 596 FISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNG 655
+ M+ + SK A I +L E +++ EK+ K L+ +D ++
Sbjct: 1807 KLHEMEGAVKSKFKSTIAALE---AKIAQLEEQVEQEAREKQAATKSLKQ-KDKKLKE-- 1860
Query: 656 RNVQKEDRTPMAEEYSE 672
+Q ED MAE+Y E
Sbjct: 1861 ILLQVEDERKMAEQYKE 1877
Score = 37.0 bits (84), Expect = 0.062
Identities = 90/496 (18%), Positives = 180/496 (36%), Gaps = 39/496 (7%)
Query: 31 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 90
S +S L++ +S E G S + L A A Q ++ +E
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1100
Query: 91 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 150
D + K N L+ I + QE + A ++ + ++ +
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160
Query: 151 ELHDNQDGLVNMESLNSTRSHERTGPD---DFEWMSDERKGNEKDGGHTQHFESPTMKIQ 207
EL D D + L + R E T D E S E + E H Q E T +++
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE 1220
Query: 208 EHPSLSDTKQQRNQDAGDQEESFVSEVP---QSDLTALCDEKNWEEPIPAFSSWQRENSD 264
+ + Q + E+ Q+ +K E + S + + +
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS-KCSDGE 1279
Query: 265 SDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRS 324
A L+ + +L ++ E ML+ A G++ + D + S
Sbjct: 1280 RARAELNDKVHKLQNEV--ESVTGMLNE---AEGKAIKLAKD-------------VASLS 1321
Query: 325 SSLGSYDD--EQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVL-- 380
S L + ++E ++ +++ L+++ +D+ +EE + + + + +
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 381 ---KWTNDLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQELV 435
K D A L+E K + +E +LT + +++ K ++ + E +V
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 436 DKAIKPSVEATLESIQRKLQEKRAE----SSRPEDIKDMTKDQI-ANEKVALQKALLYYE 490
D + + + LE QRK + AE SS+ D +D + + E AL A E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 491 SIHGRPVTKNERQVMK 506
++ + + +++K
Sbjct: 1502 ALEAKEELERTNKMLK 1517
Score = 36.2 bits (82), Expect = 0.11
Identities = 69/370 (18%), Positives = 139/370 (37%), Gaps = 48/370 (12%)
Query: 346 IQSLKKKIRKFEDRFEEEKKYRPSHSDK--AANPEVLKWTNDLAKFRRQLKESKLKISEE 403
+ +L+KK RKF+ EEK ++D+ A E + R L+E+ L+ EE
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA-LEAKEE 1508
Query: 404 DLTPRMRQRSNTLPKSFGSQL--EKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAES 461
+R+N + K+ L K+D K + K ++E +E ++ +L+E E
Sbjct: 1509 ------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Query: 462 SRPEDIK------------DMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLY 509
ED K +D A ++ +K +H + + + L
Sbjct: 1563 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1622
Query: 510 DRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPI--IEGETASFFKEIKEEEEGSEDDSN 567
+ K++ + + + K R ++ + ++ + F +E+ E+ S D+
Sbjct: 1623 AAAK--KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-EDARASRDEI- 1678
Query: 568 VKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLH-AASIPELL 626
F + + A+ +AD D + + L A + L
Sbjct: 1679 ----FATAKENEKKAKSL------EADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 627 EHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVL 686
+++EK+R+ ++ E+ + G DR A + +E +L L
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE--------QLSNEL 1780
Query: 687 ISKRDTDSKS 696
++R T K+
Sbjct: 1781 ATERSTAQKN 1790
Score = 32.7 bits (73), Expect = 1.2
Identities = 97/569 (17%), Positives = 226/569 (39%), Gaps = 76/569 (13%)
Query: 132 GCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGP-----DDFEWMSDER 186
G ++ KRQ+ T + + N + + + R + P E M +
Sbjct: 806 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865
Query: 187 KGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEK 246
+K Q E+ ++++ S ++ Q+ E +E + + ++
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 925
Query: 247 NWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSD---------PMLSPRFYAY 297
EE + + E D + L + ++ +Q+LD + + + A
Sbjct: 926 ELEEILHEMEARLEEEEDRGQ-QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984
Query: 298 GQSRQYLDDTEVPPSPPNSHSFMRRR--------SSSLGSYDDEQEDLTPAQLTRR--IQ 347
+ ++ D+ V N S R+ +++L +++ ++LT + I
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 348 SLKKKIRKFE-DRFEEEKKYRPSHSDKAA-NPEVLKWTNDLAKFRRQL--KESKLKISEE 403
L+ +++K E R E EK R D + + ++ +A+ + QL KE +L+ +
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 404 DLTPRMRQRSNTLPK-----SFGSQLEKEDEKKQELVDKAIKPSVEA--TLESIQRKLQE 456
L + Q++N L K S L+++ + ++ +KA K + LE+++ +L++
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 457 KRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVK 516
++ ++++ + ++ K AL + +E+ + + + Q ++ L ++ K
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 517 QILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTL 576
+ ++AN K + L E E A E++ + ++ + K +
Sbjct: 1224 R--AKANL--------DKNKQTL-----EKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 577 KTDFSARCFLDQFEDDADGFISPMDDKI---PSKCSQDTGLSN----------LHAASIP 623
+ + ++C D + + ++DK+ ++ TG+ N AS+
Sbjct: 1269 Q-ELQSKC------SDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1321
Query: 624 ELLEHLQEMREEKKR----IRKKLRDFED 648
L+ QE+ +E+ R + KLR E+
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEE 1350
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 48.1 bits (113), Expect = 3e-05
Identities = 94/377 (24%), Positives = 152/377 (40%), Gaps = 55/377 (14%)
Query: 333 EQEDLTPAQ--LTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390
E EDL ++ + + + L+K R E + EE K D+ L+ T D AK R
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE------LQATED-AKLR 1564
Query: 391 RQLKESKLKIS-EEDLTPRMRQ----RSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEA 445
++ LK E DL R Q R + + E EDE+KQ + A K +E
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1624
Query: 446 TLESIQRKLQEKRAESSRPEDIKDMTK--DQIANEKVALQKALLYYESIHGRPVTKNER- 502
L+ ++ LQ A R E IK + K Q+ + + L+ A + I +NE+
Sbjct: 1625 DLKDLE--LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA-TAKENEKK 1681
Query: 503 ---------QVMKPLYDRYRLVKQI-LSRANTIPIIGSPSSKRRSPLLQP---IIEGETA 549
Q+ + L R KQ L + + S S R + LQ +E A
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA--LQDEKRRLEARIA 1739
Query: 550 SFFKEIKEEE--------------EGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADG 595
+E++EE+ + +E SN T + + SAR L++ +
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
Query: 596 FISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNG 655
+ M+ + SK A I +L E +++ EK+ K L+ +D ++
Sbjct: 1800 KLHEMEGAVKSKFKSTIAALE---AKIAQLEEQVEQEAREKQAATKSLKQ-KDKKLKE-- 1853
Query: 656 RNVQKEDRTPMAEEYSE 672
+Q ED MAE+Y E
Sbjct: 1854 ILLQVEDERKMAEQYKE 1870
Score = 37.0 bits (84), Expect = 0.062
Identities = 90/496 (18%), Positives = 180/496 (36%), Gaps = 39/496 (7%)
Query: 31 SNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQD 90
S +S L++ +S E G S + L A A Q ++ +E
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 91 EVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLS 150
D + K N L+ I + QE + A ++ + ++ +
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153
Query: 151 ELHDNQDGLVNMESLNSTRSHERTGPD---DFEWMSDERKGNEKDGGHTQHFESPTMKIQ 207
EL D D + L + R E T D E S E + E H Q E T +++
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE 1213
Query: 208 EHPSLSDTKQQRNQDAGDQEESFVSEVP---QSDLTALCDEKNWEEPIPAFSSWQRENSD 264
+ + Q + E+ Q+ +K E + S + + +
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS-KCSDGE 1272
Query: 265 SDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRS 324
A L+ + +L ++ E ML+ A G++ + D + S
Sbjct: 1273 RARAELNDKVHKLQNEV--ESVTGMLNE---AEGKAIKLAKD-------------VASLS 1314
Query: 325 SSLGSYDD--EQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVL-- 380
S L + ++E ++ +++ L+++ +D+ +EE + + + + +
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 381 ---KWTNDLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQELV 435
K D A L+E K + +E +LT + +++ K ++ + E +V
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 436 DKAIKPSVEATLESIQRKLQEKRAE----SSRPEDIKDMTKDQI-ANEKVALQKALLYYE 490
D + + + LE QRK + AE SS+ D +D + + E AL A E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 491 SIHGRPVTKNERQVMK 506
++ + + +++K
Sbjct: 1495 ALEAKEELERTNKMLK 1510
Score = 36.2 bits (82), Expect = 0.11
Identities = 69/370 (18%), Positives = 139/370 (37%), Gaps = 48/370 (12%)
Query: 346 IQSLKKKIRKFEDRFEEEKKYRPSHSDK--AANPEVLKWTNDLAKFRRQLKESKLKISEE 403
+ +L+KK RKF+ EEK ++D+ A E + R L+E+ L+ EE
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA-LEAKEE 1501
Query: 404 DLTPRMRQRSNTLPKSFGSQL--EKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAES 461
+R+N + K+ L K+D K + K ++E +E ++ +L+E E
Sbjct: 1502 ------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Query: 462 SRPEDIK------------DMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLY 509
ED K +D A ++ +K +H + + + L
Sbjct: 1556 QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 510 DRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPI--IEGETASFFKEIKEEEEGSEDDSN 567
+ K++ + + + K R ++ + ++ + F +E+ E+ S D+
Sbjct: 1616 AAAK--KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-EDARASRDEI- 1671
Query: 568 VKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLH-AASIPELL 626
F + + A+ +AD D + + L A + L
Sbjct: 1672 ----FATAKENEKKAKSL------EADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 627 EHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVL 686
+++EK+R+ ++ E+ + G DR A + +E +L L
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAE--------QLSNEL 1773
Query: 687 ISKRDTDSKS 696
++R T K+
Sbjct: 1774 ATERSTAQKN 1783
Score = 32.7 bits (73), Expect = 1.2
Identities = 97/569 (17%), Positives = 226/569 (39%), Gaps = 76/569 (13%)
Query: 132 GCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGP-----DDFEWMSDER 186
G ++ KRQ+ T + + N + + + R + P E M +
Sbjct: 799 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
Query: 187 KGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEK 246
+K Q E+ ++++ S ++ Q+ E +E + + ++
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918
Query: 247 NWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSD---------PMLSPRFYAY 297
EE + + E D + L + ++ +Q+LD + + + A
Sbjct: 919 ELEEILHEMEARLEEEEDRGQ-QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
Query: 298 GQSRQYLDDTEVPPSPPNSHSFMRRR--------SSSLGSYDDEQEDLTPAQLTRR--IQ 347
+ ++ D+ V N S R+ +++L +++ ++LT + I
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 348 SLKKKIRKFE-DRFEEEKKYRPSHSDKAA-NPEVLKWTNDLAKFRRQL--KESKLKISEE 403
L+ +++K E R E EK R D + + ++ +A+ + QL KE +L+ +
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 404 DLTPRMRQRSNTLPK-----SFGSQLEKEDEKKQELVDKAIKPSVEA--TLESIQRKLQE 456
L + Q++N L K S L+++ + ++ +KA K + LE+++ +L++
Sbjct: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
Query: 457 KRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVK 516
++ ++++ + ++ K AL + +E+ + + + Q ++ L ++ K
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEA-QVQEMRQKHAQAVEELTEQLEQFK 1216
Query: 517 QILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTL 576
+ ++AN K + L E E A E++ + ++ + K +
Sbjct: 1217 R--AKANL--------DKNKQTL-----EKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 577 KTDFSARCFLDQFEDDADGFISPMDDKI---PSKCSQDTGLSN----------LHAASIP 623
+ + ++C D + + ++DK+ ++ TG+ N AS+
Sbjct: 1262 Q-ELQSKC------SDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
Query: 624 ELLEHLQEMREEKKR----IRKKLRDFED 648
L+ QE+ +E+ R + KLR E+
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 46.2 bits (108), Expect = 1e-04
Identities = 88/385 (22%), Positives = 162/385 (42%), Gaps = 46/385 (11%)
Query: 333 EQEDLTPAQ--LTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390
+ EDL ++ + + + L+K R E + EE + D+ L+ T D AK R
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDE------LQATED-AKLR 1564
Query: 391 RQLKESKLKIS-EEDLTPRMRQ---RSNTLPKSFGS-QLEKEDEKKQELVDKAIKPSVEA 445
++ +K E DL R Q + L K + E EDE+KQ + A K +E
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEI 1624
Query: 446 TLESIQRKLQEKRAESSRPEDIKDMTK--DQIANEKVALQKALLYYESIHGRPVTKNER- 502
L+ ++ +++ A +R E IK + K Q+ + + L++A + I + ++
Sbjct: 1625 DLKDLEAQIE--AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKL 1682
Query: 503 --------QVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLL--QPIIEGETASFF 552
Q+ + L R + + + + S+ +S LL + +E A
Sbjct: 1683 KSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE 1742
Query: 553 KEIKEEEEGSE--DDSNVKPDFMV-TLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCS 609
+E++EE+ E +D K V TL + +A Q D+A + + ++ +K
Sbjct: 1743 EELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQ 1802
Query: 610 QDTG---------LSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQK 660
+ G +S L A I +L E L++ +E+ K +R E + +Q
Sbjct: 1803 ELEGAVKSKFKATISALE-AKIGQLEEQLEQEAKERAAANKLVRRTEK---KLKEIFMQV 1858
Query: 661 EDRTPMAEEYSEYKHIKAKLRLLEV 685
ED A++Y E KA R+ ++
Sbjct: 1859 EDERRHADQYKEQME-KANARMKQL 1882
Score = 45.8 bits (107), Expect = 1e-04
Identities = 78/382 (20%), Positives = 157/382 (41%), Gaps = 64/382 (16%)
Query: 333 EQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEK---------KYRPSHSDKAANPEVLKWT 383
E+E+ L + ++ I+ E++ +EE+ K K E+L
Sbjct: 932 EEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLE 991
Query: 384 NDLAKFRRQLK-------ESKLKISEEDLTPR----MRQRSNTLPKSFGSQLEKEDEKKQ 432
+ +KF ++ K E +++EE+ + +R + + +L+KE++ +Q
Sbjct: 992 DQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ 1051
Query: 433 ELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLY--YE 490
EL +KA K ++ +Q ++ E +A+ D K Q+A ++ LQ AL E
Sbjct: 1052 EL-EKA-KRKLDGETTDLQDQIAELQAQI-------DELKLQLAKKEEELQGALARGDDE 1102
Query: 491 SIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETAS 550
++H K R++ + + LQ E E AS
Sbjct: 1103 TLHKNNALKVVRELQAQIAE-----------------------------LQEDFESEKAS 1133
Query: 551 FFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQ 610
K K++ + SE+ +K + TL T + + + E + ++++ + +Q
Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193
Query: 611 DTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFE-DNFFRQNGRNVQKEDRTPMAEE 669
+ HA ++ EL E L++ + K + K + E DN ++ V K + AE
Sbjct: 1194 IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDN--KELACEV-KVLQQVKAES 1250
Query: 670 YSEYKHIKAKLRLLEVLISKRD 691
+ K + A+++ L +S+ D
Sbjct: 1251 EHKRKKLDAQVQELHAKVSEGD 1272
>gi|56549111 optineurin [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/324 (21%), Positives = 128/324 (39%), Gaps = 47/324 (14%)
Query: 321 RRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAAN---- 376
R RS+ E E+LT +QL ++ +K+ + E +E K+ K +N
Sbjct: 215 RSRSADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEI 274
Query: 377 ----------------------PEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSN 414
EV + ++L+E+ K+SE +L + Q
Sbjct: 275 ETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKC 334
Query: 415 TLPKSFGSQLEKEDEKKQELV--DKAIKPSVEATLESIQRKLQEKRAESSRPE-DIKDMT 471
+ S + E +KQELV +K ++ VE+ L I K+++ + E + + + MT
Sbjct: 335 QALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEI--KMEQAKTEDEKSKLTVLQMT 392
Query: 472 KDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLV-KQILSRANTIPIIGS 530
+++ E AL E + + K +R V+K L ++ L K + S+ + +
Sbjct: 393 HNKLLQEH---NNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQ 449
Query: 531 PSSKRRSPL-----LQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCF 585
+K+ L L+ +E + F E E+ E+ + V LK +
Sbjct: 450 TIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKEN------ 503
Query: 586 LDQFEDDADGFISPMDDKIPSKCS 609
D FED + M + ++ S
Sbjct: 504 -DAFEDGGRQSLMEMQSRHGARTS 526
>gi|56549109 optineurin [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/324 (21%), Positives = 128/324 (39%), Gaps = 47/324 (14%)
Query: 321 RRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAAN---- 376
R RS+ E E+LT +QL ++ +K+ + E +E K+ K +N
Sbjct: 215 RSRSADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEI 274
Query: 377 ----------------------PEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSN 414
EV + ++L+E+ K+SE +L + Q
Sbjct: 275 ETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKC 334
Query: 415 TLPKSFGSQLEKEDEKKQELV--DKAIKPSVEATLESIQRKLQEKRAESSRPE-DIKDMT 471
+ S + E +KQELV +K ++ VE+ L I K+++ + E + + + MT
Sbjct: 335 QALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEI--KMEQAKTEDEKSKLTVLQMT 392
Query: 472 KDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLV-KQILSRANTIPIIGS 530
+++ E AL E + + K +R V+K L ++ L K + S+ + +
Sbjct: 393 HNKLLQEH---NNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQ 449
Query: 531 PSSKRRSPL-----LQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCF 585
+K+ L L+ +E + F E E+ E+ + V LK +
Sbjct: 450 TIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKEN------ 503
Query: 586 LDQFEDDADGFISPMDDKIPSKCS 609
D FED + M + ++ S
Sbjct: 504 -DAFEDGGRQSLMEMQSRHGARTS 526
>gi|20149572 optineurin [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/324 (21%), Positives = 128/324 (39%), Gaps = 47/324 (14%)
Query: 321 RRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAAN---- 376
R RS+ E E+LT +QL ++ +K+ + E +E K+ K +N
Sbjct: 215 RSRSADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEI 274
Query: 377 ----------------------PEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSN 414
EV + ++L+E+ K+SE +L + Q
Sbjct: 275 ETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKC 334
Query: 415 TLPKSFGSQLEKEDEKKQELV--DKAIKPSVEATLESIQRKLQEKRAESSRPE-DIKDMT 471
+ S + E +KQELV +K ++ VE+ L I K+++ + E + + + MT
Sbjct: 335 QALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEI--KMEQAKTEDEKSKLTVLQMT 392
Query: 472 KDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLV-KQILSRANTIPIIGS 530
+++ E AL E + + K +R V+K L ++ L K + S+ + +
Sbjct: 393 HNKLLQEH---NNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQ 449
Query: 531 PSSKRRSPL-----LQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCF 585
+K+ L L+ +E + F E E+ E+ + V LK +
Sbjct: 450 TIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKEN------ 503
Query: 586 LDQFEDDADGFISPMDDKIPSKCS 609
D FED + M + ++ S
Sbjct: 504 -DAFEDGGRQSLMEMQSRHGARTS 526
>gi|56549107 optineurin [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/324 (21%), Positives = 128/324 (39%), Gaps = 47/324 (14%)
Query: 321 RRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAAN---- 376
R RS+ E E+LT +QL ++ +K+ + E +E K+ K +N
Sbjct: 215 RSRSADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEI 274
Query: 377 ----------------------PEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSN 414
EV + ++L+E+ K+SE +L + Q
Sbjct: 275 ETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKC 334
Query: 415 TLPKSFGSQLEKEDEKKQELV--DKAIKPSVEATLESIQRKLQEKRAESSRPE-DIKDMT 471
+ S + E +KQELV +K ++ VE+ L I K+++ + E + + + MT
Sbjct: 335 QALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEI--KMEQAKTEDEKSKLTVLQMT 392
Query: 472 KDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLV-KQILSRANTIPIIGS 530
+++ E AL E + + K +R V+K L ++ L K + S+ + +
Sbjct: 393 HNKLLQEH---NNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQ 449
Query: 531 PSSKRRSPL-----LQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCF 585
+K+ L L+ +E + F E E+ E+ + V LK +
Sbjct: 450 TIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKEN------ 503
Query: 586 LDQFEDDADGFISPMDDKIPSKCS 609
D FED + M + ++ S
Sbjct: 504 -DAFEDGGRQSLMEMQSRHGARTS 526
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 45.8 bits (107), Expect = 1e-04
Identities = 134/692 (19%), Positives = 245/692 (35%), Gaps = 130/692 (18%)
Query: 54 DVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKG--LINKENT-PSGF 110
D +SG +D + + + R ++ ++++ G KG + + EN P
Sbjct: 21 DERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDRED---GLPKGHHVTDSENDEPLNL 77
Query: 111 NHLDDCILNTQEVEKVH--KNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNST 168
N D E E++H K++ + ER++P S +N+D VN +S
Sbjct: 78 NASDS------ESEELHRQKDSDSESEERAEPPASDS--------ENED--VNQHGSDSE 121
Query: 169 RSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHP-SLSDTKQQRNQDAGDQE 227
R P + + E GH +S + +HP S S+ ++ + A D E
Sbjct: 122 SEETRKLP------GSDSENEELLNGHAS--DSENEDVGKHPASDSEIEELQKSPASDSE 173
Query: 228 ESFVSEVPQSDLTA-------LCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQ 280
+ SD + D +N E P P S + E + S Q
Sbjct: 174 TEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQ 233
Query: 281 LLDEDSDPMLSPRFY---AYGQSRQYLDDTEVP--PSPPNSHSFMRRRSSSLGSYDDEQE 335
D +++ + PR + R D+E P P S S + S D E E
Sbjct: 234 ASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQAS-DSENE 292
Query: 336 DLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPS-----HSDKAANPEVLKWTNDLAKFR 390
+L +++ +K + E+ +++ SD+ E + ND
Sbjct: 293 ELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSD 352
Query: 391 RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESI 450
+ K S+ + +Q+ ++ EDEK+ E ++ + A L
Sbjct: 353 SHMDRKKFHSSDSEEEEHKKQKMDS----------DEDEKEGE--EEKVAKRKAAVLSDS 400
Query: 451 QRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD 510
+ + + +S D D D ++++ +K + + +E + K L D
Sbjct: 401 EDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTI----------ASDSEEEAGKELSD 450
Query: 511 RYRLVKQILSRANTIPIIGSPSSKRRSPLLQPII-------EGETASFFKEIKEEEEG-- 561
+ K + S S L+ I E E F +E EEE+G
Sbjct: 451 KKNEEKDLFGS-------DSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGET 503
Query: 562 -------SEDDSNVKP----------DFMVTLKTDFSARCFLDQ----FEDDADGFISPM 600
S+ D N+K + M+ K S + ++ F DAD +S M
Sbjct: 504 QVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAM 563
Query: 601 DDKIPSKCSQDTGLSNLHAAS------IPELLEHLQEMREEKKRIRKKLRDFEDNFFRQN 654
K+ +D L+N + +P ++ HL K +D ++ F
Sbjct: 564 IVKMNEAAEEDRQLNNQKKPALKKLTLLPAVVMHL------------KKQDLKETFIDSG 611
Query: 655 GRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVL 686
+ KE +P+ + +K + LL++L
Sbjct: 612 VMSAIKEWLSPLPDR--SLPALKIREELLKIL 641
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 45.4 bits (106), Expect = 2e-04
Identities = 72/365 (19%), Positives = 151/365 (41%), Gaps = 40/365 (10%)
Query: 333 EQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQ 392
E+E+ L + +++ I++ E++ EEE+ R + E AK ++
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTE--------AKLKKL 976
Query: 393 LKESKLKISEEDLTPRMRQRSNTLP---KSFGSQLEKEDEKKQELVDKAIKPSVEATLES 449
+E +I ED ++ + L F + L +E+EK + L +K EA +
Sbjct: 977 EEE---QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA--KLKNKHEAMITD 1031
Query: 450 IQRKL-----QEKRAESSRPEDIKDMT--KDQIANEKVALQKALLYYESIHGRPVTKNER 502
++ +L Q + E +R + D T DQIA + + + + + K E
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM--------QLAKKEE 1083
Query: 503 QVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGS 562
++ L R+ ++ + + I S+ LQ +E E AS K K++ +
Sbjct: 1084 ELQAAL---ARVEEEAAQKNMALKKIRELESQISE--LQEDLESERASRNKAEKQKRDLG 1138
Query: 563 EDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASI 622
E+ +K + TL + + + + E + + ++++ + +Q + H+ ++
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV 1198
Query: 623 PELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRL 682
EL E L E+ KR++ L + + G + + SE+K K + +L
Sbjct: 1199 EELAEQL----EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 683 LEVLI 687
E+ +
Sbjct: 1255 QELQV 1259
Score = 42.7 bits (99), Expect = 0.001
Identities = 70/335 (20%), Positives = 135/335 (40%), Gaps = 47/335 (14%)
Query: 334 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 393
Q D ++LT+ +L+ +++ ++ +EE + + S S K E ++ FR QL
Sbjct: 1291 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVE-----DEKNSFREQL 1345
Query: 394 KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRK 453
+E EE+ + ++ TL +K ++ L T E ++RK
Sbjct: 1346 EE------EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL----------ETAEEVKRK 1389
Query: 454 LQEKRAESSRPEDIKDMTKDQIANEKVALQKAL--LYYESIHGRPVTKNERQVMKPLYDR 511
LQ+ S+ + K D++ K LQ+ L L + H +RQ L +
Sbjct: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDH-------QRQSACNLEKK 1442
Query: 512 YRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGET--ASFFKEIKEEEEGSEDDSNVK 569
+ Q+L+ T I + ++ R E ET S + ++E E + +
Sbjct: 1443 QKKFDQLLAEEKT---ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLN 1499
Query: 570 PDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHL 629
F ++ S++ DD + ++ SK + + + + + EL + L
Sbjct: 1500 KQFRTEMEDLMSSK-------DDVGKSVHELE---KSKRALEQQVEEM-KTQLEELEDEL 1548
Query: 630 QEMREEKKRIRKKLRDFEDNFFRQ-NGRNVQKEDR 663
Q + K R+ L+ + F R GR+ Q E++
Sbjct: 1549 QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEK 1583
Score = 39.3 bits (90), Expect = 0.012
Identities = 66/350 (18%), Positives = 148/350 (42%), Gaps = 30/350 (8%)
Query: 340 AQLTRRIQSLKKKIRKFED-------RFEEE--KKYRPSHSDKAANPEVLKWTNDLAKFR 390
A+L +I LK ++ K E+ R EEE +K + ++ + DL R
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 391 --RQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLE 448
R E + + E+L + +TL S +Q E +++QE+ +K ++E +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLD-STAAQQELRSKREQEV--NILKKTLEEEAK 1181
Query: 449 SIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPL 508
+ + ++QE R + S+ + +Q K L+KA E+ G + + +++
Sbjct: 1182 THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGE-LANEVKVLLQGK 1240
Query: 509 YDRYRLVKQILSRANTIPIIGSPSSKRRSPL------LQPIIEGETASFFKEIKEEEEGS 562
D K++ ++ + + + + R+ L LQ ++ T + + + +
Sbjct: 1241 GDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLT 1300
Query: 563 EDDSNVKPDFMVTL-------KTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLS 615
+D S ++ T + S L Q ED+ + F ++++ +K + + ++
Sbjct: 1301 KDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIA 1360
Query: 616 NLHA--ASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDR 663
LHA A + + +E E + +++KL+ + +++ V D+
Sbjct: 1361 TLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDK 1410
Score = 38.5 bits (88), Expect = 0.021
Identities = 87/392 (22%), Positives = 158/392 (40%), Gaps = 60/392 (15%)
Query: 333 EQEDLTPAQ--LTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFR 390
E EDL ++ + + + L+K R E + EE K D+ L+ T D AK R
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDE------LQATED-AKLR 1557
Query: 391 RQLKESKLKIS-EEDLTPRMRQRSNTLPKSFGSQL-----EKEDEKKQELVDKAIKPSVE 444
++ +K E DL R Q S K Q+ E EDE+KQ + A + +E
Sbjct: 1558 LEVNLQAMKAQFERDLQGRDEQ-SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLE 1616
Query: 445 ATLESIQRKLQEKRAESSRPEDIKDMTKDQI--------ANEKVALQKALLYYESIHGRP 496
L+ ++ + A +R E IK + K Q ++ A ++ +L + +
Sbjct: 1617 MDLKDLEAHIDS--ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674
Query: 497 VTKNER---QVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQP--IIEGETASF 551
+ E Q+ + L R +Q + + + SS + + L+ +E A
Sbjct: 1675 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1734
Query: 552 FKEIKEEEEGSE--DDSNVKPDFMV-TLKTDF-----------SARCFLDQFEDDADGFI 597
+E++EE+ +E +D K + + + TD +AR L++ + +
Sbjct: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794
Query: 598 SPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMRE----EKKRIRKKLRDFEDNFFRQ 653
M+ + SK A + E L++ + R+ + +R KKL+D
Sbjct: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV------- 1847
Query: 654 NGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEV 685
+Q +D AE+Y + KA RL ++
Sbjct: 1848 ---LLQVDDERRNAEQYKDQAD-KASTRLKQL 1875
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 45.4 bits (106), Expect = 2e-04
Identities = 94/455 (20%), Positives = 193/455 (42%), Gaps = 92/455 (20%)
Query: 259 QRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHS 318
+R +S+ +AH Q +L R+ L + D +L+ F +Q L
Sbjct: 1461 RRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF----SLKQQL-------------- 1502
Query: 319 FMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPE 378
E++D+ A T+++ SL+ ++ +D +E K D+A+
Sbjct: 1503 --------------EEKDMDIAGFTQKVVSLEAEL---QDISSQESK------DEAS--- 1536
Query: 379 VLKWTNDLAKFRRQLK--ESKLKISEEDLTPRMRQRSNTLP--KSFGSQLEKEDEKKQEL 434
LAK ++QL+ E+K+K EE+L +++ T+ + +LE E E+ ++
Sbjct: 1537 -------LAKVKKQLRDLEAKVKDQEEELD----EQAGTIQMLEQAKLRLEMEMERMRQT 1585
Query: 435 VDKAIKP---SVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYES 491
K ++ VE +S Q+KL K+ E E+ +D K ++ EK L+ L
Sbjct: 1586 HSKEMESRDEEVEEARQSCQKKL--KQMEVQLEEEYED--KQKVLREKRELEGKLATLSD 1641
Query: 492 IHGRPVTKNERQVMKPLYDRYRLVKQILSRANTI--PIIGSPSSKRRSPLLQPIIEGETA 549
R ++E+++ K L + K +L+ A + + S SKR L+ +E
Sbjct: 1642 QVNRRDFESEKRLRKDL----KRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
Query: 550 SFFKEIKEEE--EGSEDDSNVKPDFMVTLKTDFSARC---------FLDQFEDDADGFIS 598
+ +K + E +D +++ D + KT + ++ E+D +
Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDM-- 1755
Query: 599 PMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFED--NFFRQN-- 654
+++ K ++ A I +L L+E +EK+ +++KL+ + F Q+
Sbjct: 1756 ---NELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV 1812
Query: 655 GRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISK 689
+++ + E + + + +++ LE L S+
Sbjct: 1813 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASR 1847
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 45.4 bits (106), Expect = 2e-04
Identities = 94/455 (20%), Positives = 193/455 (42%), Gaps = 92/455 (20%)
Query: 259 QRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHS 318
+R +S+ +AH Q +L R+ L + D +L+ F +Q L
Sbjct: 1461 RRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF----SLKQQL-------------- 1502
Query: 319 FMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPE 378
E++D+ A T+++ SL+ ++ +D +E K D+A+
Sbjct: 1503 --------------EEKDMDIAGFTQKVVSLEAEL---QDISSQESK------DEAS--- 1536
Query: 379 VLKWTNDLAKFRRQLK--ESKLKISEEDLTPRMRQRSNTLP--KSFGSQLEKEDEKKQEL 434
LAK ++QL+ E+K+K EE+L +++ T+ + +LE E E+ ++
Sbjct: 1537 -------LAKVKKQLRDLEAKVKDQEEELD----EQAGTIQMLEQAKLRLEMEMERMRQT 1585
Query: 435 VDKAIKP---SVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYES 491
K ++ VE +S Q+KL K+ E E+ +D K ++ EK L+ L
Sbjct: 1586 HSKEMESRDEEVEEARQSCQKKL--KQMEVQLEEEYED--KQKVLREKRELEGKLATLSD 1641
Query: 492 IHGRPVTKNERQVMKPLYDRYRLVKQILSRANTI--PIIGSPSSKRRSPLLQPIIEGETA 549
R ++E+++ K L + K +L+ A + + S SKR L+ +E
Sbjct: 1642 QVNRRDFESEKRLRKDL----KRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
Query: 550 SFFKEIKEEE--EGSEDDSNVKPDFMVTLKTDFSARC---------FLDQFEDDADGFIS 598
+ +K + E +D +++ D + KT + ++ E+D +
Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDM-- 1755
Query: 599 PMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFED--NFFRQN-- 654
+++ K ++ A I +L L+E +EK+ +++KL+ + F Q+
Sbjct: 1756 ---NELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV 1812
Query: 655 GRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISK 689
+++ + E + + + +++ LE L S+
Sbjct: 1813 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASR 1847
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.7 bits (104), Expect = 3e-04
Identities = 73/410 (17%), Positives = 164/410 (40%), Gaps = 65/410 (15%)
Query: 81 QRRRQSKEQD-EVRHGRDKGLINKENTPSGFNHLDDCILN------TQEVEKVHKNTFGC 133
QRRRQ +E++ E++ ++ + + +D + +QE + K +
Sbjct: 819 QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQL 878
Query: 134 AGER--------SKPKRQKSSTKLSELHDNQDGLVNMESLNSTR---------SHERTGP 176
ER +KP Q+ K +L ++ + E R E+
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 177 DDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQ 236
++ + + +ER+ + Q+ + ++ +E L + ++R + +++ E+ Q
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 237 SDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYA 296
+ L +E+ W+R+ DE L + +L+R+ E L R
Sbjct: 999 EEEQLLREEREKRRR----QEWERQYRKKDE--LQQEEEQLLRE---EREKRRLQER--- 1046
Query: 297 YGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKF 356
RQY ++ E+ +E++ L + TRR Q L+++ RK
Sbjct: 1047 ---ERQYREEEELQ--------------------QEEEQLLGEERETRRRQELERQYRKE 1083
Query: 357 EDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQ----LKESKLKISEEDLTPRMRQR 412
E+ +EE++ +K E + + + +++ L+E + K ++L + R+
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 413 SNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQ--RKLQEKRAE 460
+ E+ ++++++ +++ + E E Q R+ QEKR +
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Score = 43.9 bits (102), Expect = 5e-04
Identities = 88/457 (19%), Positives = 182/457 (39%), Gaps = 41/457 (8%)
Query: 135 GERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKD-- 192
G+R + KRQ+ +L+E + + +E + R E EW E + E++
Sbjct: 134 GQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL 193
Query: 193 ----GGHTQHF-ESPTMKIQEHPSLS----DTKQQRNQDAGDQ--EESFVSEVPQSDLTA 241
G T+ F + ++ +E L + KQQ+ ++ D+ +E E + +
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
Query: 242 LCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSR 301
+E+ +E P QRE + +E + L R+ +E+ R Q R
Sbjct: 254 RKEEEKLQEEEP---QRQRELQEEEEQLRKLERQELRRERQEEEQQQQ---RLRREQQLR 307
Query: 302 QYLDDTEVPPSPPNSHSFMRRRSSSLGSYDD---EQEDLTPAQLTRRIQSLKKKIRKFED 358
+ ++ RR EQE+ QL R + +++ + +
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 359 RFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPK 418
+ EE ++ + + + L+ L + ++ +E +L+ ++ + +R L +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 419 SFGSQLEKEDEKK--QELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIA 476
Q E+ E+K QE ++ +K E + ++R+ + +R E R + + + +DQ
Sbjct: 428 E---QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK--QQLKRDQ-- 480
Query: 477 NEKVALQKALLYYESIHGRPVTKNERQVMKPLYDR--YRLVKQ-----ILSRANTIPIIG 529
E+ ++ L E + E+Q+ + +R RL +Q + R + +
Sbjct: 481 -EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 530 SPSSKRRSPLLQPIIEGETASFFKE--IKEEEEGSED 564
+RR LL+ E +E +K E+E D
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Score = 41.6 bits (96), Expect = 0.003
Identities = 91/525 (17%), Positives = 202/525 (38%), Gaps = 61/525 (11%)
Query: 80 RQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGE-RS 138
++R RQ +E++E++ ++ L+ +E L+ +E+++ + E R
Sbjct: 1044 QERERQYREEEELQQEEEQ-LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 139 KPKRQKSSTKLSELHDNQDGLVN--------MESLNSTRSHERTGPDDFEWMSDERKGNE 190
+ +R++ + EL ++ L+ E R E ++ + + +E +
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 191 KDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQ------------EESFVSEVPQSD 238
+ Q+ E ++ +E L + +++R Q+ Q ++ + E +SD
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Query: 239 L---------TALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPM 289
L A+ D K + + Q E+S + Q+ + ++ LL E +
Sbjct: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR----QSQQDLQHLLGEQQERD 1278
Query: 290 LSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSL 349
+ Q ++ + E + R R S +++Q + RR Q
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ----EEKQLLREEREEKRRRQET 1334
Query: 350 KKKIRKFEDRFEE--EKKYRPSHSDKAANPEVLKWTNDLAKF-------RRQLKESKLKI 400
+K R+ E +E E+ R D+ E L+ KF RRQ +E K
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK 1394
Query: 401 SEEDLTPRMRQRSNTLPKSFGSQLEKEDEK--KQELVDKAIKPSVEATLESIQRKLQEKR 458
E+ L R ++R L + + +E+++ +QE K + + + +RK E+
Sbjct: 1395 EEQQL--RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Query: 459 AESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQI 518
+ + K ++Q+ E+ Q + R + E+Q+ + DR +++
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQ----LHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508
Query: 519 LSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSE 563
S+ + R + ++ E ++++ +E G +
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEE-----QQLRRQERGQQ 1548
Score = 40.4 bits (93), Expect = 0.006
Identities = 75/425 (17%), Positives = 160/425 (37%), Gaps = 44/425 (10%)
Query: 80 RQRRRQSKEQDEVRHG-------------RDKGLINKENTPSGFNHLDDCILNTQEVEKV 126
RQ+R+Q ++ R RD + K F L+D L ++ ++
Sbjct: 1207 RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD 1266
Query: 127 HKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDER 186
++ G ER + ++++ + + H ++ + E + +R ++ + + +ER
Sbjct: 1267 LQHLLGEQQERDR-EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
Query: 187 KGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQE-------ESFVSEVPQSDL 239
+ + + F +QE +Q+R++ ++E F+ E + L
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEE--EQRL 1383
Query: 240 TALCDEKNW---EEPIPAFSSWQRENSDSD------EAHLSPQAGRLIRQLLDEDSDPML 290
E+ + E+ + Q+ D D E LS Q R+ +E+
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD--RKFREEEQQVRR 1441
Query: 291 SPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLK 350
R + + Q L R L + +++ L Q RR Q
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR-QERD 1500
Query: 351 KKIRKFEDRF---------EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKIS 401
+K R+ E R EE++ +R K E + + RRQ ++ K +
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 402 EEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAES 461
E+ R Q+ + + +LE++ ++QE K ++ + + Q++L+++R
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 462 SRPED 466
R ++
Sbjct: 1621 FREDE 1625
Score = 39.3 bits (90), Expect = 0.012
Identities = 53/230 (23%), Positives = 101/230 (43%), Gaps = 25/230 (10%)
Query: 339 PAQLTRRIQSLKKKIRKFEDRF---EEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKE 395
P + R Q ++ ++ E RF EEEK+ R + + L++ + + +R+ +
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQR--RRQRREREKELQFLEEEEQLQRRERA 846
Query: 396 SKLKISEEDLTP-RMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKL 454
+L+ E+ L + R+RS + + + E+E+K+ KP+++ L Q+ L
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 455 QEKRAESSRPEDIKDMTKDQ----IANEKVALQKALLYYESIHGRPVTKNERQVMKPLYD 510
QE+ E R E K ++Q E++ ++ L E R + ERQ
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ------- 959
Query: 511 RYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEE 560
YR K++ + ++G KRR + E +E+++EEE
Sbjct: 960 -YRKDKKLQQKEE--QLLGEEPEKRRRQEREKKYREE-----EELQQEEE 1001
Score = 37.7 bits (86), Expect = 0.036
Identities = 36/164 (21%), Positives = 79/164 (48%), Gaps = 20/164 (12%)
Query: 322 RRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFE------EEKKYRPSHSDKAA 375
RR L ++E+ +L +R++S ++ R+ E+R E EEK+ ++
Sbjct: 514 RREQRLKRQEEEE------RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
Query: 376 NPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELV 435
E + + L K + ++ +LK +E+ R+ QR L + +LE+E+ ++Q L
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEE---RLEQR---LKREEVERLEQEERREQRL- 620
Query: 436 DKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEK 479
K +P E + ++ + QE+R + + ++ + ++ E+
Sbjct: 621 -KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663
Score = 32.3 bits (72), Expect = 1.5
Identities = 73/393 (18%), Positives = 147/393 (37%), Gaps = 67/393 (17%)
Query: 81 QRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKP 140
Q+ R+ + Q ++R RD+ D+ +L +E +++H+ +P
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFRE-----------DEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 141 KRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFE 200
+ ++ + HD E L E + + E+D + +
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQ------------EGEEQQLRRQERDRKFREEEQ 1698
Query: 201 SPTMKIQEHPSLSDTKQQRNQDAGD---QEESFVSEVPQSDLTA------LCDEKNW--E 249
+ +E L + +Q R Q+ +EE E Q L + +E+ E
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 250 EPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEV 309
+R+ +E L + R +QL ++SD +F Q RQ ++ ++
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQE--REEQQLRSQESDR----KFREEEQLRQEREEQQL 1812
Query: 310 PPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPS 369
P + G Y E+E L + +R++ + + + E++F ++K R
Sbjct: 1813 RPQQRD------------GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 370 HSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDE 429
+ W + K RRQ +E KL+ EE + R +Q+ + G +E +
Sbjct: 1861 EQE--------LWQEEEQK-RRQERERKLR--EEHI--RRQQKEEQRHRQVGEIKSQEGK 1907
Query: 430 KKQELVDKAIK--PSVEATLESIQRKLQEKRAE 460
L++ SV + +QE+R++
Sbjct: 1908 GHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
Score = 32.0 bits (71), Expect = 2.0
Identities = 75/424 (17%), Positives = 154/424 (36%), Gaps = 64/424 (15%)
Query: 81 QRRRQSKEQDEVRHGRDKGL-INKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSK 139
Q R Q QD R R++ ++++ F + + + K + ER +
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 140 PKRQKSST----KLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGH 195
R++ + +LH + +E R ER D ++ E + E +
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER----DRKFREQELRSQEPERKF 1517
Query: 196 TQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAF 255
+ + + ++ L + +Q R Q+ G Q D K EE
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR------------DRKFREE----- 1560
Query: 256 SSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPN 315
++ + +E LS Q R + L+E + Q R++++D +
Sbjct: 1561 ---EQLRQEREEQQLSRQE-RDRKFRLEEQ-------KVRRQEQERKFMEDEQQLRRQEG 1609
Query: 316 SHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFED------RFEEEKKYRPS 369
+ R + ++ QL R+ ++ RKF + R E E++ R
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQ-----ERDRKFLEEEPQLRRQEREQQLRHD 1664
Query: 370 HSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDE 429
K E L + + RRQ ++ K + E+ L + R+R L++E +
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER---------KFLQEEQQ 1715
Query: 430 KKQELVDKAIKPSVEATLESIQRKLQEK-------RAESSRPEDIKDMTKDQIANEKVAL 482
+++ +++ + + E+ Q +L+ + E RPE + + Q + K
Sbjct: 1716 LRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Query: 483 QKAL 486
++ L
Sbjct: 1776 EEQL 1779
Score = 31.2 bits (69), Expect = 3.4
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 28/212 (13%)
Query: 321 RRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVL 380
RRR S L ++E+ R Q +++ R F +++ E+K +A P +
Sbjct: 740 RRRESELQWQEEER--------AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLR 791
Query: 381 KWTN-DLAKFRRQLKESKLKISEEDLTPRMRQR-------------SNTLPKSFGSQLEK 426
+ L RQ +E + EE+ R RQR + QL++
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 427 EDEKKQELVDKAIKPSVEATLESIQR-KLQEKRAESSRPEDIKDMTKDQIANEKVALQKA 485
E++ QE D+ + S E + R +L+E+R K ++Q+ E+ LQ+
Sbjct: 852 EEDGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 486 LLYYESIHGRPVTKNERQVMKPLYDRYRLVKQ 517
E + K RQ + Y ++Q
Sbjct: 910 ---EEELQREEREKRRRQEQERQYREEEQLQQ 938
Score = 29.6 bits (65), Expect = 9.9
Identities = 63/331 (19%), Positives = 125/331 (37%), Gaps = 34/331 (10%)
Query: 185 ERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTALCD 244
E++ + H Q +K ++ K++ + +QE + L +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR------KQQLKRDQE 481
Query: 245 EKNWEEPIPAFSSWQRENSDSDEAHLS-PQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQY 303
E+ E + +RE + E L Q R ++L ++ + L R + Q R+
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 304 LDDT--EVPPSPPNSHSFMRRRSSSLGSYDDEQED-LTPAQLTRRIQSLKKK-------- 352
++ ++ RR L +E+ D L + RR Q LK++
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 353 -----IRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLK-------ESKLKI 400
+ + E E++ + ++ ++LK + ++QL+ E +LK
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 401 SEEDLTPRMR-QRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRA 459
EE+ R +R + + E+E E+ +E + I P + LES Q K
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI-PKWQWQLESEADARQSK-- 718
Query: 460 ESSRPEDIKDMTKDQIANEKVALQKALLYYE 490
SRP + + Q EK +++ L ++
Sbjct: 719 VYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 44.7 bits (104), Expect = 3e-04
Identities = 77/378 (20%), Positives = 137/378 (36%), Gaps = 47/378 (12%)
Query: 76 ATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAG 135
++ R + E +E++ + + KE + ++ + E EK K
Sbjct: 375 SSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVK------- 427
Query: 136 ERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGH 195
+ +++ + SE D V + + +RS + ++ K E+D H
Sbjct: 428 DHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK----------EKSKSKERDSKH 477
Query: 196 TQHFES---PTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQS--DLTALCDEKNWEE 250
++ E K ++H ++ + ++Q + DQE S E + + D +E
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537
Query: 251 PIPAFSSWQRE----------NSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQS 300
S RE NS + E S R +R D D S ++ Y +
Sbjct: 538 KDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRT-HDRDRSRSKEYHRYREQ 596
Query: 301 ------RQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIR 354
R + PP S RRR S S +E + + R Q K R
Sbjct: 597 EYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKY--RNQESKSSHR 654
Query: 355 KFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSN 414
K E+ E++ Y S ++N K + R Q SK+K S +D + N
Sbjct: 655 K-ENSESEKRMYSKSRDHNSSNNSREKKAD-----RDQSPFSKIKQSSQDNELKSSMLKN 708
Query: 415 TLPKSFGSQLEKEDEKKQ 432
+ S +EKE++K +
Sbjct: 709 KEDEKIRSSVEKENQKSK 726
Score = 34.7 bits (78), Expect = 0.31
Identities = 85/487 (17%), Positives = 185/487 (37%), Gaps = 49/487 (10%)
Query: 33 VSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSAS--------SATSARQRRR 84
+ + GEL+ ++ E+ ++S SS DS+S + S S SAT + ++R
Sbjct: 171 ILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKR 230
Query: 85 QSK--------EQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNTF----- 131
+ K ++++ + + K + E+ + +E+ + +N F
Sbjct: 231 KKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKS 290
Query: 132 -GCAGERSKPKRQKSSTKLSELHDNQDGLVNMESL--NSTRSHERTGPDDFEWMSDERKG 188
A E+ + R++ + ++Q L S R + GP + S R
Sbjct: 291 PPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSR 350
Query: 189 NEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVSEVPQSDLTA----LCD 244
+ T M+ + +S ++ D + E + E +S + + D
Sbjct: 351 DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNE--IKENQRSPVRVKERKITD 408
Query: 245 EKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYL 304
+N E + + E + H S R IR+ ++D + A +SR
Sbjct: 409 HRNVSES----PNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKS 464
Query: 305 DD---TEVPPSPPNSHSFMRRRSSSLGS-----YDDEQEDLTPAQLTRRIQSLKKKIRKF 356
+ ++ S N + R RS S G + E++ + + R +S K+K ++
Sbjct: 465 KEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRS-KEKSKQL 523
Query: 357 EDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL-KESKLKISEEDLTPRMRQRSNT 415
E + E + D+ A + D+ K + ++ + D + R+R R++
Sbjct: 524 ESKSNEHDHSKSKEKDRRAQSRSREC--DITKGKHSYNSRTRERSRSRDRSRRVRSRTHD 581
Query: 416 LPKSFGSQLEKEDEKKQELVDKA---IKPSVEATLESIQRKLQEKRAESSRPEDIKDMTK 472
+S + + E++ ++ + + S R+ + + + SS E+ + K
Sbjct: 582 RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNK 641
Query: 473 DQIANEK 479
D+ N++
Sbjct: 642 DKYRNQE 648
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 44.3 bits (103), Expect = 4e-04
Identities = 99/414 (23%), Positives = 166/414 (40%), Gaps = 54/414 (13%)
Query: 291 SPRFYAYGQSRQYLD---DTEVPPSP---PNSHSFMRRRSSSLGSYDDEQEDLTPAQLTR 344
S RF +S+Q L+ DT +P S +S S +R G+ D R
Sbjct: 41 SQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKIRVLLQERGAQD------------R 88
Query: 345 RIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEED 404
RIQ L+ ++ K E R + + S S A E L + R + K K SE
Sbjct: 89 RIQDLETELEKMEARLNAALREKTSLSANNATLE-----KQLIELTRTNELLKSKFSENG 143
Query: 405 LTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRP 464
+R S L K K + K + ++ K + +E L+ QR L+E + + ++
Sbjct: 144 NQKNLRILSLELMKL----RNKRETKMRGMMAK--QEGMEMKLQVTQRSLEESQGKIAQL 197
Query: 465 EDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANT 524
E + + +EK +K L Y E I + QV K D +L + + + +
Sbjct: 198 EGKLVSIEKEKIDEKSETEKLLEYIEEI-----SCASDQVEKYKLDIAQLEENLKEKNDE 252
Query: 525 IPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEE----GSEDDSNVKPDFMVTLKTDF 580
I + S + +L +E KE+E+ E + N+ + M LK F
Sbjct: 253 ILSL-KQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAE-MQNLKQKF 310
Query: 581 SARCFLDQFEDDADGFISPMDDKIPSKCSQDTGL-SNLHAASIPELLEHLQEMREEKKRI 639
L+Q E + + + +I S Q+ L S+LH +L +EM +EK
Sbjct: 311 ----ILEQQEREK---LQQKELQIDSLLQQEKELSSSLH----QKLCSFQEEMVKEKNLF 359
Query: 640 RKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTD 693
++L+ D + + Q E EE E K +L+LLE + ++ +
Sbjct: 360 EEELKQTLDELDKLQQKEEQAERLVKQLEE--EAKSRAEELKLLEEKLKGKEAE 411
>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
Length = 860
Score = 44.3 bits (103), Expect = 4e-04
Identities = 67/313 (21%), Positives = 122/313 (38%), Gaps = 56/313 (17%)
Query: 346 IQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEV--LKWTNDLAKFRR---QLKESKLKI 400
++ K+ + +F + E K KA ++ L ND+ + Q E+K
Sbjct: 96 LEDCKEVLLEFRKKIAENKA-------KAVRKDIQRLSLNNDIFEANSDSDQQSETKEDT 148
Query: 401 SEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAE 460
S + ++RQR P L+K+ K +L DK+ KP +E++LES+ L+ K+
Sbjct: 149 SPKKKKKKLRQREEKSP----DDLKKKKAKAGKLKDKS-KPDLESSLESLVFDLRTKKRI 203
Query: 461 SSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILS 520
S E++K+ K + ++V K L + V K E ++ + +
Sbjct: 204 SEAKEELKESKKPK--KDEVKETKEL--------KKVKKGE-------------IRDLKT 240
Query: 521 RANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDF 580
+ P + R + +E + S + + +D + D +
Sbjct: 241 KTREDP------KENRKTKKEKFVESQVESESSVLNDSPFPEDDSEGLHSDSREEKQNTK 294
Query: 581 SARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMRE------ 634
SAR Q GF P+D + ++ +DT + P E +E R+
Sbjct: 295 SARERAGQDMGLEHGFEKPLDSAMSAE--EDTDVRGRRKKKTPRKAEDTRENRKLENKNA 352
Query: 635 --EKKRIRKKLRD 645
EKK + KK R+
Sbjct: 353 FLEKKTVPKKQRN 365
Score = 30.0 bits (66), Expect = 7.6
Identities = 46/217 (21%), Positives = 87/217 (40%), Gaps = 13/217 (5%)
Query: 60 GQSSEDSESGTLSASSATSARQ-RRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCIL 118
G+ E G S SA ++ +R +SKE+ + RH DK ++ P G L + I
Sbjct: 388 GRRLSGEERGLWSTDSAEEDKETKRNESKEKYQKRHDSDKEEKGRKE-PKGLKTLKE-IR 445
Query: 119 NTQEVEKVHKNTFGCAGERSKPKRQ-KSSTKLSELHDNQDGLVNMESLNSTRSHERT--- 174
N ++ K+ E ++ + + K + H ++ +++ +TR T
Sbjct: 446 NAFDLFKLTPEEKNDVSENNRKREEIPLDFKTIDDHKTKENKQSLKERRNTRDETDTWAY 505
Query: 175 --GPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQ-EHPSLSDTKQQRNQDAGDQEESFV 231
D E + + +E G Q S M +Q E L D Q++ D D+ +
Sbjct: 506 IAAEGDQEVLDSVCQADENSDGR-QQILSLGMDLQLEWMKLEDF--QKHLDGKDENFAAT 562
Query: 232 SEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEA 268
+P + L ++ A +S + N D +++
Sbjct: 563 DAIPSNVLRDAVKNGDYITVKVALNSNEEYNLDQEDS 599
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 43.5 bits (101), Expect = 7e-04
Identities = 100/418 (23%), Positives = 167/418 (39%), Gaps = 46/418 (11%)
Query: 291 SPRFYAYGQSRQYLD---DTEVPPSPPNSHSFMRRRSSSLGSYDD---EQEDLTPAQ--- 341
S RF +S+Q L+ DT +P S S ++ S D E+E Q
Sbjct: 41 SQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKKESQKNDKDLKILEKEIRVLLQERG 100
Query: 342 -LTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKI 400
RRIQ L+ ++ K E R + + S S A E L + R + K K
Sbjct: 101 AQDRRIQDLETELEKMEARLNAALREKTSLSANNATLE-----KQLIELTRTNELLKSKF 155
Query: 401 SEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAE 460
SE +R S L K K + K + ++ K + +E L+ QR L+E + +
Sbjct: 156 SENGNQKNLRILSLELMKL----RNKRETKMRGMMAK--QEGMEMKLQVTQRSLEESQGK 209
Query: 461 SSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILS 520
++ E + + +EK +K L Y E I + QV K D +L + +
Sbjct: 210 IAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI-----SCASDQVEKYKLDIAQLEENLKE 264
Query: 521 RANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEE----GSEDDSNVKPDFMVTL 576
+ + I + S + +L +E KE+E+ E + N+ + M L
Sbjct: 265 KNDEILSL-KQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAE-MQNL 322
Query: 577 KTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGL-SNLHAASIPELLEHLQEMREE 635
K F L+Q E + + + +I S Q+ L S+LH +L +EM +E
Sbjct: 323 KQKF----ILEQQEREK---LQQKELQIDSLLQQEKELSSSLH----QKLCSFQEEMVKE 371
Query: 636 KKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTD 693
K ++L+ D + + Q E EE E K +L+LLE + ++ +
Sbjct: 372 KNLFEEELKQTLDELDKLQQKEEQAERLVKQLEE--EAKSRAEELKLLEEKLKGKEAE 427
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 43.1 bits (100), Expect = 9e-04
Identities = 74/391 (18%), Positives = 150/391 (38%), Gaps = 47/391 (12%)
Query: 334 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 393
Q+D A + +++L+ K+ K E + S DKA + +++ + L K L
Sbjct: 634 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNK----L 689
Query: 394 KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQEL------------VDKAIKP 441
+E+++K+ E ++ + +F SQL+ +EK +L K ++
Sbjct: 690 QEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQ 749
Query: 442 SVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNE 501
+EA + I+ EK AESS+ I T++ E E + + E
Sbjct: 750 QLEAAEKQIKHLEIEKNAESSKASSI---TRELQGRELKLTNLQENLSEVSQVKETLEKE 806
Query: 502 RQVMKPLY------------DRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETA 549
Q++K + V ++ + ++ S K R L A
Sbjct: 807 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLAD-----MEA 861
Query: 550 SFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMD-DKIPSKC 608
F ++ + EE+ + ++ D +K L + D+ + D +++ K
Sbjct: 862 KFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELR--LKERDVEELQLKL 919
Query: 609 SQDTGLSNLHAASIPELL--------EHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQK 660
++ ++ SI ++ E ++ EEKK + +KL D E + + +
Sbjct: 920 TKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQEL 979
Query: 661 EDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 691
+ R A ++ KH + L + L+ D
Sbjct: 980 KARYERATSETKTKHEEILQNLQKTLLDTED 1010
Score = 30.8 bits (68), Expect = 4.4
Identities = 80/352 (22%), Positives = 145/352 (41%), Gaps = 61/352 (17%)
Query: 333 EQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYR-----PSHSDKAANPEVLK----WT 383
E D +L +++ K+K+ + R EEE + + S+K+ E+ K
Sbjct: 418 EAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRV 477
Query: 384 NDLAKFRRQLKESK--------LKISEE--------DLTPRMRQRSNT-LPKSFGSQLEK 426
++A+ RR+L+ +K L + +E ++T QR T L + FG++ E
Sbjct: 478 QEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREET 537
Query: 427 EDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKAL 486
++ + L K S E ES++ KL+ E+S D+ + K ++ + Q+A+
Sbjct: 538 HQKEIKALYTATEKLSKEN--ESLKSKLEHANKENS---DVIALWKSKLETAIASHQQAM 592
Query: 487 --LYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPII 544
L G E +K ++ RL Q + I + + R+ + +
Sbjct: 593 EELKVSFSKGLGTETAEFAELKTQIEKMRLDYQ-----HEIENLQNQQDSERAAHAKE-M 646
Query: 545 EGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFED------DADGFIS 598
E A K IKE+E E + K D + L + ED +A+ +
Sbjct: 647 EALRAKLMKVIKEKENSLE---------AIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 697
Query: 599 PMDDKIPSKCSQDTGL-----SNLHAASIPEL-LEHLQEMREEKKRIRKKLR 644
+ + + +KC++ T + S L A L L+ L++ E K KKLR
Sbjct: 698 EL-EVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLR 748
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,066,239
Number of Sequences: 37866
Number of extensions: 1389172
Number of successful extensions: 6888
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 436
Number of HSP's that attempted gapping in prelim test: 6018
Number of HSP's gapped (non-prelim): 1229
length of query: 697
length of database: 18,247,518
effective HSP length: 109
effective length of query: 588
effective length of database: 14,120,124
effective search space: 8302632912
effective search space used: 8302632912
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.