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Search of human proteins with 62865621
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
(811 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865621 toll-like receptor 10 precursor [Homo sapiens] 1652 0.0
gi|62865618 toll-like receptor 10 precursor [Homo sapiens] 1652 0.0
gi|41350337 toll-like receptor 1 [Homo sapiens] 742 0.0
gi|20143971 toll-like receptor 6 [Homo sapiens] 730 0.0
gi|19718734 toll-like receptor 2 [Homo sapiens] 347 3e-95
gi|20302168 toll-like receptor 8 [Homo sapiens] 146 7e-35
gi|19924149 toll-like receptor 4 precursor [Homo sapiens] 143 7e-34
gi|16751843 toll-like receptor 5 [Homo sapiens] 140 6e-33
gi|4507531 toll-like receptor 3 [Homo sapiens] 137 5e-32
gi|7706093 toll-like receptor 7 [Homo sapiens] 133 6e-31
gi|8394456 toll-like receptor 9 isoform A precursor [Homo sapiens] 94 4e-19
gi|167555127 CD180 molecule [Homo sapiens] 75 3e-13
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 65 2e-10
gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] 63 1e-09
gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] 63 1e-09
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 63 1e-09
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 63 1e-09
gi|31542244 leucine rich repeat and fibronectin type III domain ... 63 1e-09
gi|38454322 adhesion molecule with Ig-like domain 3 [Homo sapiens] 61 4e-09
gi|72534676 leucine rich repeat containing 17 isoform 1 [Homo sa... 61 5e-09
gi|4502403 biglycan preproprotein [Homo sapiens] 61 5e-09
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho... 61 5e-09
gi|40217820 slit and trk like 3 protein [Homo sapiens] 60 8e-09
gi|21361633 leucine rich repeat containing 40 [Homo sapiens] 60 1e-08
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ... 59 1e-08
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens] 57 5e-08
gi|4759146 slit homolog 2 [Homo sapiens] 57 9e-08
gi|109150416 peroxidasin [Homo sapiens] 56 1e-07
gi|27436867 slit and trk like 4 protein [Homo sapiens] 56 1e-07
gi|16418445 leucine rich repeat containing 3B [Homo sapiens] 55 2e-07
>gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 1652 bits (4278), Expect = 0.0
Identities = 811/811 (100%), Positives = 811/811 (100%)
Query: 1 MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLL 60
MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLL
Sbjct: 1 MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLL 60
Query: 61 FQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLR 120
FQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLR
Sbjct: 61 FQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLR 120
Query: 121 YLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHY 180
YLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHY
Sbjct: 121 YLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHY 180
Query: 181 EEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLE 240
EEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLE
Sbjct: 181 EEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLE 240
Query: 241 NAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMR 300
NAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMR
Sbjct: 241 NAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMR 300
Query: 301 TIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNIL 360
TIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNIL
Sbjct: 301 TIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNIL 360
Query: 361 TDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWP 420
TDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWP
Sbjct: 361 TDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWP 420
Query: 421 ETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTD 480
ETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTD
Sbjct: 421 ETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTD 480
Query: 481 LPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYS 540
LPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYS
Sbjct: 481 LPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYS 540
Query: 541 EVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLH 600
EVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLH
Sbjct: 541 EVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLH 600
Query: 601 FDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKED 660
FDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKED
Sbjct: 601 FDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKED 660
Query: 661 GSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHE 720
GSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHE
Sbjct: 661 GSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHE 720
Query: 721 NSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVL 780
NSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVL
Sbjct: 721 NSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVL 780
Query: 781 ATREMYELQTFTELNEESRGSTISLMRTDCL 811
ATREMYELQTFTELNEESRGSTISLMRTDCL
Sbjct: 781 ATREMYELQTFTELNEESRGSTISLMRTDCL 811
>gi|62865618 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 1652 bits (4278), Expect = 0.0
Identities = 811/811 (100%), Positives = 811/811 (100%)
Query: 1 MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLL 60
MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLL
Sbjct: 1 MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLL 60
Query: 61 FQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLR 120
FQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLR
Sbjct: 61 FQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLR 120
Query: 121 YLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHY 180
YLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHY
Sbjct: 121 YLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHY 180
Query: 181 EEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLE 240
EEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLE
Sbjct: 181 EEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLE 240
Query: 241 NAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMR 300
NAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMR
Sbjct: 241 NAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMR 300
Query: 301 TIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNIL 360
TIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNIL
Sbjct: 301 TIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNIL 360
Query: 361 TDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWP 420
TDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWP
Sbjct: 361 TDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWP 420
Query: 421 ETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTD 480
ETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTD
Sbjct: 421 ETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTD 480
Query: 481 LPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYS 540
LPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYS
Sbjct: 481 LPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYS 540
Query: 541 EVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLH 600
EVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLH
Sbjct: 541 EVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLH 600
Query: 601 FDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKED 660
FDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKED
Sbjct: 601 FDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKED 660
Query: 661 GSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHE 720
GSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHE
Sbjct: 661 GSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHE 720
Query: 721 NSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVL 780
NSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVL
Sbjct: 721 NSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVL 780
Query: 781 ATREMYELQTFTELNEESRGSTISLMRTDCL 811
ATREMYELQTFTELNEESRGSTISLMRTDCL
Sbjct: 781 ATREMYELQTFTELNEESRGSTISLMRTDCL 811
>gi|41350337 toll-like receptor 1 [Homo sapiens]
Length = 786
Score = 742 bits (1915), Expect = 0.0
Identities = 389/782 (49%), Positives = 528/782 (67%), Gaps = 12/782 (1%)
Query: 6 NIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQS 65
+I+ F I M +L EE E + + S L VP DL+ TT L++S N + +L +
Sbjct: 3 SIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISELWT 62
Query: 66 SDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLS 125
SD S+SKLR+LI+ HNRIQ LD+ F+FN+EL YLDLS+N+L ++ + L++LDLS
Sbjct: 63 SDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLDLS 122
Query: 126 FNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEG-- 183
FN FD +PIC+E GNMS L+ LGLS ++KS IAHL+++ V L +E
Sbjct: 123 FNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKEDPE 182
Query: 184 SLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDG--KSQFVSYEMQRNLSLE- 240
L NT LHIV P + F +L +KT LE++NI + SY + L+
Sbjct: 183 GLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKLQT 242
Query: 241 NAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMR 300
N K S L LN ++ W+ ILQ VWHT+V +F I NV G+ LD FDYS T ++
Sbjct: 243 NPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQ--LDFRDFDYSGTSLK 300
Query: 301 TIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNIL 360
+ + V VF Q IY + + M+I+N T+S +M HML P+ + F +L+F+NN+L
Sbjct: 301 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 360
Query: 361 TDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTP-LEHLDLSQNLLQHKNDE-NCS 418
TD +F+ L L+TLIL N+L+ LS ++ L+ LD+SQN + + + +CS
Sbjct: 361 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 420
Query: 419 WPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFL 478
W ++++++N+S N L+D++FRCLP I++LDL++N+I+++PK+ + L AL+ELN+AFN L
Sbjct: 421 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 480
Query: 479 TDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQ-LE 537
TDLPGC FS LSVL I+ N + PS DF QSCQ+++++ AG NPF+CTCEL F++ ++
Sbjct: 481 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 540
Query: 538 TYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFC 597
S ++ GW DSY C+YP + RGT LKD H+ ELSCN LLIVTIV MLVL + V
Sbjct: 541 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 600
Query: 598 CLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLE 657
C + DLPWYLRM+ Q TQT R R E+L+RN++FHAFISYS HDS WVKNEL+PNLE
Sbjct: 601 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 660
Query: 658 KEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNL 717
KE + ICL+E F PGKSI ENI++ IEKSYKSIFVLSPNFVQ+EWCHYE YFAHHNL
Sbjct: 661 KE--GMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNL 718
Query: 718 FHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINV 777
FHE S+ +ILILLEPIP Y IP+ YHKLK+L+ ++ YLEWPK++ K GLFWANLRAAIN+
Sbjct: 719 FHEGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINI 778
Query: 778 NV 779
+
Sbjct: 779 KL 780
>gi|20143971 toll-like receptor 6 [Homo sapiens]
Length = 796
Score = 730 bits (1885), Expect = 0.0
Identities = 382/799 (47%), Positives = 527/799 (65%), Gaps = 21/799 (2%)
Query: 3 LIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQ 62
++++ + C +++ G + + E + S L VP DL T LD+S N + +
Sbjct: 8 IVKSFHFVCLMIIIV-GTRIQFSDGNEFAVDKSKRGLIHVPKDLPLKTKVLDMSQNYIAE 66
Query: 63 LQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYL 122
LQ SD +S+L VL L HNRIQ LDL F+FN++L YLDLS+N+L+ ++ + + R+L
Sbjct: 67 LQVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQKISCHPIVSFRHL 126
Query: 123 DLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRT--LPHY 180
DLSFNDF +PIC+E GN+S L LGLS K+QK D IAHLHL+ + L R +
Sbjct: 127 DLSFNDFKALPICKEFGNLSQLNFLGLSAMKLQKLDLLPIAHLHLSYILLDLRNYYIKEN 186
Query: 181 EEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNI----DGKSQFVSY--EMQ 234
E SL ILN LH+V + F + + + T L++TNI D F+ + E+
Sbjct: 187 ETESLQILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELT 246
Query: 235 RNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDY 294
R +L N LN ++ W L + QF+W VE+ I N+T + F Y
Sbjct: 247 RGSTLLN-----FTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIES--IREEDFTY 299
Query: 295 SNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLN 354
S T ++ + +EH+ +VF Q +Y + ++M+I LTIS+ HML P+ P+ F++LN
Sbjct: 300 SKTTLKALTIEHITNQVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFLN 359
Query: 355 FANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTP-LEHLDLSQNLLQH-K 412
F N+ TD +F++ L L+TLIL N L+ L V + P LE LD+S N L+ +
Sbjct: 360 FTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMTKDMPSLEILDVSWNSLESGR 419
Query: 413 NDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELN 472
+ ENC+W E++V +NLS N L+DSVFRCLP I++LDL++N+I++VPK+ + L AL+ELN
Sbjct: 420 HKENCTWVESIVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQELN 479
Query: 473 IAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKN 532
+AFN LTDLPGC FS LSVL I+ N + PS DF QSCQ+++++ AG NPF+CTCEL+
Sbjct: 480 VAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELRE 539
Query: 533 FIQ-LETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLG 591
F++ ++ S ++ GW DSY C+YP + RG+ LKD H+ ELSCN LLIVTI MLVL
Sbjct: 540 FVKNIDQVSSEVLEGWPDSYKCDYPESYRGSPLKDFHMSELSCNITLLIVTIGATMLVLA 599
Query: 592 LAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNE 651
+ V C++ DLPWYLRM+ Q TQT R R E+L+RN++FHAFISYSEHDS WVK+E
Sbjct: 600 VTVTSLCIYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSEHDSAWVKSE 659
Query: 652 LIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFY 711
L+P LEKED I ICL+E F PGKSI ENI++ IEKSYKSIFVLSPNFVQ+EWCHYE Y
Sbjct: 660 LVPYLEKED--IQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELY 717
Query: 712 FAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANL 771
FAHHNLFHE S+++ILILLEPIP IP +YHKLKAL+ ++ YL+WPK++ K GLFWAN+
Sbjct: 718 FAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQRTYLQWPKEKSKRGLFWANI 777
Query: 772 RAAINVNVLATREMYELQT 790
RAA N+ + E ++++
Sbjct: 778 RAAFNMKLTLVTENNDVKS 796
>gi|19718734 toll-like receptor 2 [Homo sapiens]
Length = 784
Score = 347 bits (890), Expect = 3e-95
Identities = 238/785 (30%), Positives = 394/785 (50%), Gaps = 33/785 (4%)
Query: 9 IFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDF 68
+ S+ + L +R + S+ SL +P+ LT A +LDLS N + + +SD
Sbjct: 13 VIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDL 72
Query: 69 HSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVT--WYL-LAGLRYLDLS 125
L+ L+L N I ++ +F L +LDLS N L +++ W+ L+ L +L+L
Sbjct: 73 QRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLL 132
Query: 126 FNDFDTMPICEEAGNMSHLEILGLSG----AKIQKSDFQKIAHLHLNTVFLGFRTLPHYE 181
N + T+ +++ L+IL + KIQ+ DF + L + + L YE
Sbjct: 133 GNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLE--ELEIDASDLQSYE 190
Query: 182 EGSLPILNTTKLHIVLPMDTNFWVL--LRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSL 239
SL + H++L M + +L D + + LE+ + D + S + +
Sbjct: 191 PKSLKSIQNVS-HLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFS---ELSTGE 246
Query: 240 ENAKTSVLLLNKVDLLWDDLFLILQFVWHTS-VEHFQIRNVTFGGKAYLDHNSFD--YSN 296
N+ V + + LF +++ + S + + + T G + D
Sbjct: 247 TNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDP 306
Query: 297 TVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQ--MPHMLFPNYPTKFQYLN 354
+ T+ + +H FY+ D L ++ +T+ N++ + L + +YL+
Sbjct: 307 GKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLD 366
Query: 355 FANNILTDELFKRTI---QLPHLKTLILNGNKLETLSLVS-CFANNTPLEHLDLSQNLLQ 410
+ N++ +E K + P L+TLIL N L +L L ++D+S+N
Sbjct: 367 LSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSF- 425
Query: 411 HKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRE 470
H E C WPE + +NLS ++ SV C+PK+++ILD++NN + +++L L+E
Sbjct: 426 HSMPETCQWPEKMKYLNLSSTRIH-SVTGCIPKTLEILDVSNNNLNLF---SLNLPQLKE 481
Query: 471 LNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCEL 530
L I+ N L LP S L VL I N I + S + + S +KTL AG N F C+CE
Sbjct: 482 LYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEF 541
Query: 531 KNFIQLETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVL 590
+F Q + +++ W +Y C+ P ++RG +++DV L C+ L+ + + +L
Sbjct: 542 LSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLL 601
Query: 591 GLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKN 650
L C F WY++M+ W + ++ ++ RN+ + AF+SYSE D+ WV+N
Sbjct: 602 ILLTGVLCHRFHGLWYMKMMW----AWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVEN 657
Query: 651 ELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEF 710
++ LE + +CL++ F PGK I +NI+ IEKS+K++FVLS NFV++EWC YE
Sbjct: 658 LMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYEL 717
Query: 711 YFAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWAN 770
F+H LF EN+D ILILLEPI IP R+ KL+ ++ K YLEWP D + FW N
Sbjct: 718 DFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVN 777
Query: 771 LRAAI 775
LRAAI
Sbjct: 778 LRAAI 782
>gi|20302168 toll-like receptor 8 [Homo sapiens]
Length = 1041
Score = 146 bits (369), Expect = 7e-35
Identities = 186/770 (24%), Positives = 332/770 (43%), Gaps = 92/770 (11%)
Query: 68 FHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRL-----KSVTWYLLAGLRYL 122
F ++++LR L L +++++ F+ L+ LDL N L +L L L
Sbjct: 283 FQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEIL 342
Query: 123 DLSFNDF-----DTMPICEEAGNMSHLEILGLSG---AKIQKSDFQKIAHL-HLNTVFLG 173
DLSFN + I + L L L G ++++ DFQ + L +L+T+ LG
Sbjct: 343 DLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLG 402
Query: 174 FRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDG-------------IKTSKILEMT 220
+ + N + L I+ + L++D I+ + +
Sbjct: 403 INFIKQIDFKLFQ--NFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDF- 459
Query: 221 NIDGKSQFVSYEMQRNLSLENA----KTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQI 276
D S F Y R L K L LN + + + F L + ++
Sbjct: 460 EFDPHSNF--YHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSN 517
Query: 277 RNVTFGGK-------AYLD--HNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMD 327
V G + YLD +N D+ N T E V + + Y + +
Sbjct: 518 AQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALT---ELSDLEVLDLSYNSHYFRIAGVT 574
Query: 328 IENLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETL 387
H+ F T + LN ++N + K ++ L L+ +GN+L+ L
Sbjct: 575 -----------HHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDIL 623
Query: 388 ------SLVSCFANNTPLEHLDLSQNLLQH-KNDENCSWPETVVNMNLSYNKLSDSVFRC 440
+S F L LDLS N L+H N+ + P ++ ++++ N L +
Sbjct: 624 WNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTL 683
Query: 441 LPK--SIQILDLNNNQIQTVPKETIHLMA-LRELNIAFNFLTDLPG--CSHFSRLSVLNI 495
L + +++LDL N++ + + LR L ++ N ++ LP S S L L++
Sbjct: 684 LQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDL 743
Query: 496 EMNFI--LSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQ-LETYSEVMMVGWSDSYT 552
N + ++ S ++ ++ L NPF CTC++ +F + ++ + V + D
Sbjct: 744 SSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVD-VI 802
Query: 553 CEYPLNLRGTRLKDVHLHELSCNTALLIV---TIVVIMLVLGLAVAFCCLHFDLPWYLRM 609
C P + RG + + L + +I+ T + +V+ A+A ++D+ W++
Sbjct: 803 CASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDV-WFIYN 861
Query: 610 LGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSL---WVKNELIPNLEKE-DGSILI 665
+ +R T+Q + A+ISY D+ WV NEL +LE+ D ++L+
Sbjct: 862 VCLAKVKGYRSLSTSQ------TFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVLL 915
Query: 666 CLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHI 725
CL E +DPG +I +N++ I +S K++FVL+ + ++ FY A L EN D I
Sbjct: 916 CLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVI 975
Query: 726 ILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAI 775
I ILLEP+ + ++Y +L+ + K + L+WP + + GLFW LR +
Sbjct: 976 IFILLEPVLQH---SQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVV 1022
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 48 PATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNR 107
P LDL N L L S S LR L+L HNRI L L++LDLS+N
Sbjct: 688 PRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNL 747
Query: 108 LKSVTWYLL-----AGLRYLDLSFNDFD 130
LK++ L L L+L N F+
Sbjct: 748 LKTINKSALETKTTTKLSMLELHGNPFE 775
Score = 41.2 bits (95), Expect = 0.004
Identities = 48/174 (27%), Positives = 76/174 (43%), Gaps = 18/174 (10%)
Query: 53 LDLSYNLLFQLQSSDFHSVSKLRVLILCHN-RIQQLDLKTFEFNKELRYLDLSNNRL--- 108
LDLS N +F + + F ++ + L L N Q L F ++YLDL+NNRL
Sbjct: 486 LDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFD 545
Query: 109 KSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLN 168
+ L+ L LDLS+N AG HLE IQ K+ +L N
Sbjct: 546 NASALTELSDLEVLDLSYNSH----YFRIAGVTHHLEF-------IQNFTNLKVLNLSHN 594
Query: 169 TVFLGFRTLPHYEEGSLP--ILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMT 220
++ + E SL + + +L I+ D N ++ + G+K L+++
Sbjct: 595 NIYT-LTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLS 647
Score = 36.6 bits (83), Expect = 0.096
Identities = 34/120 (28%), Positives = 49/120 (40%), Gaps = 14/120 (11%)
Query: 23 ELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHN 82
E + ++ CSN L++VP + T LDLS N + + + F + L + L HN
Sbjct: 38 EKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHN 97
Query: 83 ----------RIQQLDLK----TFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFND 128
IQ L F K LR L L +N+L + L L L L N+
Sbjct: 98 PNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNN 157
Score = 31.2 bits (69), Expect = 4.0
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 18/98 (18%)
Query: 53 LDLSYNL-LFQLQSSDFH-----SVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNN 106
LDLSYN F++ H + + L+VL L HN I L K +K L L S N
Sbjct: 559 LDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 618
Query: 107 RLKSVTW------YL-----LAGLRYLDLSFNDFDTMP 133
RL + W Y+ L L LDLS N +P
Sbjct: 619 RL-DILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIP 655
>gi|19924149 toll-like receptor 4 precursor [Homo sapiens]
Length = 839
Score = 143 bits (360), Expect = 7e-34
Identities = 184/802 (22%), Positives = 345/802 (43%), Gaps = 86/802 (10%)
Query: 34 CSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFE 93
C ++ K+P +L +T LDLS+N L L S F S +L+VL L IQ ++ ++
Sbjct: 40 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 99
Query: 94 FNKELRYLDLSNNRLKSVTWYLLAGL---------------------------RYLDLSF 126
L L L+ N ++S+ +GL + L+++
Sbjct: 100 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 159
Query: 127 NDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLH----LN-TVFLGFRTLPHYE 181
N + + E N+++LE L LS KIQ + LH LN ++ L + +
Sbjct: 160 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 219
Query: 182 EGSLPILNTTKLHIVLPMDT-NFWVLLRDGIKTSKI--LEMTNIDGKSQFVSYEMQRNLS 238
G+ + KL + D+ N G+ ++ L + + ++
Sbjct: 220 PGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEG 279
Query: 239 LENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTV 298
L N L +D DD+ + + T+V F + +VT +N F + +
Sbjct: 280 LCNLTIEEFRLAYLDYYLDDIIDLFNCL--TNVSSFSLVSVTIERVKDFSYN-FGWQHLE 336
Query: 299 M--------RTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNY---- 346
+ T+KL+ + F +K +++D+ +L + + F
Sbjct: 337 LVNCKFGQFPTLKLKSLKRLTF--TSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQS 394
Query: 347 ---PTKFQYLNFA-NNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHL 402
T +YL+ + N ++T + + L L+ L + L+ +S S F + L +L
Sbjct: 395 DFGTTSLKYLDLSFNGVIT--MSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYL 452
Query: 403 DLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDS----VFRCLPKSIQILDLNNNQIQTV 458
D+S + + + ++ + ++ N ++ +F L +++ LDL+ Q++ +
Sbjct: 453 DISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTEL-RNLTFLDLSQCQLEQL 511
Query: 459 -PKETIHLMALRELNIAFN--FLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSC-QEV 514
P L +L+ LN++ N F D + L VL+ +N I++ +Q +
Sbjct: 512 SPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSL 571
Query: 515 KTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSC 574
LN +N F CTCE ++F+Q ++V + C P + +G + +++
Sbjct: 572 AFLNLTQNDFACTCEHQSFLQWIKDQRQLLVE-VERMECATPSDKQGMPVLSLNI-TCQM 629
Query: 575 NTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRF 634
N ++ V+++ +++V +AV +F +L +L C ++ E + +
Sbjct: 630 NKTIIGVSVLSVLVVSVVAVLVYKFYF----HLMLLAGC------IKYGRGENI-----Y 674
Query: 635 HAFISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIV-SFIEKSYKSI 693
AF+ YS D WV+NEL+ NLE+ +CL+ F PG +I+ NI+ KS K I
Sbjct: 675 DAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVI 734
Query: 694 FVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKA 753
V+S +F+Q+ WC +E+ A F + II I+L+ + + + +L LL +
Sbjct: 735 VVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQV-ELYRLLSRNT 793
Query: 754 YLEWPKDRRKCGLFWANLRAAI 775
YLEW +FW LR A+
Sbjct: 794 YLEWEDSVLGRHIFWRRLRKAL 815
Score = 33.9 bits (76), Expect = 0.62
Identities = 75/302 (24%), Positives = 121/302 (40%), Gaps = 64/302 (21%)
Query: 31 MTNCSNMSLRKVPADLTPATTTLDLSYNLLFQ---LQSSDFHSVSKLRVLILCH------ 81
+TN S+ SL V + D SYN +Q L + F L++ L
Sbjct: 307 LTNVSSFSLVSVTIERVK-----DFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSN 361
Query: 82 ---NRIQQLDLKTFEFNKELRYLDLSNNRLK-----SVTWYLLAGLRYLDLSFNDFDTMP 133
N ++DL + EF LDLS N L S + + L+YLDLSFN TM
Sbjct: 362 KGGNAFSEVDLPSLEF------LDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITM- 414
Query: 134 ICEEAGNMSHLEILGLSGAKIQKSDFQ--KIAHLHLNTVFLGFRTLPHYEEGSLPILNTT 191
+ N LE +++ DFQ + + +VFL R L + L+ +
Sbjct: 415 ----SSNFLGLE-------QLEHLDFQHSNLKQMSEFSVFLSLRNLIY--------LDIS 455
Query: 192 KLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVS--YEMQRNLSLENAKTSVLLL 249
H + + F +G+ + ++L+M + F+ + RNL+ + L
Sbjct: 456 HTHTRVAFNGIF-----NGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLD-----LSQ 505
Query: 250 NKVDLLWDDLFLILQFVWHTSVEHFQIRNV-TFGGKAYLDHNSFDYS-NTVMRTIKLEHV 307
+++ L F L + ++ H ++ TF K DYS N +M + K E
Sbjct: 506 CQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQ 565
Query: 308 HF 309
HF
Sbjct: 566 HF 567
>gi|16751843 toll-like receptor 5 [Homo sapiens]
Length = 858
Score = 140 bits (352), Expect = 6e-33
Identities = 172/750 (22%), Positives = 302/750 (40%), Gaps = 108/750 (14%)
Query: 56 SYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKS---VT 112
S+ L L+S DF S ++ ++C + ++ L KT F L+ N L S V
Sbjct: 165 SFGKLNSLKSIDF---SSNQIFLVCEHELEPLQGKTLSF------FSLAANSLYSRVSVD 215
Query: 113 WYLLAGLRYLDLSFNDFDTM--PICEEAGNMSHLEILGLSGAKIQKSD-FQKIAHLHLNT 169
W N F M I + +GN ++I G I KS F I H+
Sbjct: 216 W---------GKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMG 266
Query: 170 VFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFV 229
GF + P F L R ++ ++D FV
Sbjct: 267 AGFGFHNIKD------------------PDQNTFAGLARSSVR--------HLDLSHGFV 300
Query: 230 -SYEMQRNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLD 288
S + +L++ K L NK++ + D+ F +++ Q+ N+++ L
Sbjct: 301 FSLNSRVFETLKDLKVLNLAYNKINKIADEAFY--------GLDNLQVLNLSYNLLGELY 352
Query: 289 HNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPT 348
++F Y + I L+ H + QD+ + L K+ +L NA P+ P
Sbjct: 353 SSNF-YGLPKVAYIDLQKNHIAII---QDQTFKFLEKLQTLDLR-DNALTTIHFIPSIPD 407
Query: 349 KF----------------QYLNFANNILTD-ELFKRTIQLPHLKTLILNGNKLETLSLVS 391
F ++ + N L + ++ +++PHL+ LILN N+ + S
Sbjct: 408 IFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQ 467
Query: 392 CFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLN 451
+ N LE L L +N+LQ + W VF L +Q+L LN
Sbjct: 468 TPSENPSLEQLFLGENMLQLAWETELCW----------------DVFEGL-SHLQVLYLN 510
Query: 452 NNQIQTVPKETI-HLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQS 510
+N + ++P HL ALR L++ N LT L + L +L+I N +L+P+ D S
Sbjct: 511 HNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPDVFVS 570
Query: 511 CQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLH 570
+ L+ N F C CEL FI ++ V + G C YP + G L +
Sbjct: 571 ---LSVLDITHNKFICECELSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSLSTE 627
Query: 571 ELSCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRV--RKTTQEQL 628
L + + ++ F + + C +T R+ + Q
Sbjct: 628 GCDEEEVLKSLKFSLFIVCTVTLTLFLMTILTVTKFRGFCFICYKTAQRLVFKDHPQGTE 687
Query: 629 KRNVRFHAFISYSEHDSLWVKNELIPNLE---KEDGSILICLYESYFDPGKSISENIVSF 685
++ A++ +S D WV+N L+ +L+ + +C E F PG++ NI
Sbjct: 688 PDMYKYDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDA 747
Query: 686 IEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILILLEPIPFYCIPTRYHKL 745
I S K + ++S +F+++ WC F +A + + +I++++ + Y + ++ +
Sbjct: 748 IWNSRKIVCLVSRHFLRDGWCLEAFSYAQGRCLSDLNSALIMVVVGSLSQYQL-MKHQSI 806
Query: 746 KALLEKKAYLEWPKDRRKCGLFWANLRAAI 775
+ ++K+ YL WP+D + G F L I
Sbjct: 807 RGFVQKQQYLRWPEDLQDVGWFLHKLSQQI 836
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/92 (34%), Positives = 54/92 (58%), Gaps = 2/92 (2%)
Query: 53 LDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVT 112
L+LSYNLL +L SS+F+ + K+ + L N I + +TF+F ++L+ LDL +N L ++
Sbjct: 341 LNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTI- 399
Query: 113 WYLLAGLRYLDLSFNDFDTMPICEEAGNMSHL 144
+ + + + LS N T+P N+ HL
Sbjct: 400 -HFIPSIPDIFLSGNKLVTLPKINLTANLIHL 430
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 53 LDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNN---RLK 109
LDLS+ +F L S F ++ L+VL L +N+I ++ + F L+ L+LS N L
Sbjct: 293 LDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELY 352
Query: 110 SVTWYLLAGLRYLDLSFN 127
S +Y L + Y+DL N
Sbjct: 353 SSNFYGLPKVAYIDLQKN 370
>gi|4507531 toll-like receptor 3 [Homo sapiens]
Length = 904
Score = 137 bits (344), Expect = 5e-32
Identities = 204/822 (24%), Positives = 349/822 (42%), Gaps = 124/822 (15%)
Query: 27 ERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQ 86
E LM+N S ++ P TLDLS+N L + + L+ L+L +N+IQ
Sbjct: 127 ELHLMSN-SIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQA 185
Query: 87 LDLKTFEF--NKELRYLDLSNNRLKSVTWYLLAGL-RYLDLSFNDFDTMP-----ICEEA 138
L + + N L+ L+LS+N++K + + R L N+ P +C E
Sbjct: 186 LKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLEL 245
Query: 139 GNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLP 198
N S + L LS +++ + NT FLG + + ++ L+ L++V
Sbjct: 246 ANTS-IRNLSLSNSQLSTTS---------NTTFLGLK----WTNLTMLDLSYNNLNVV-G 290
Query: 199 MDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQ-----RNLSLENAKT----SVLLL 249
D+ W+ + LE NI S+ + R L+L+ + T S+ L
Sbjct: 291 NDSFAWLPQLEYF----FLEYNNIQ---HLFSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
Query: 250 NKVDLLWDDLFLILQFVWHTSVEHFQIRNVT---FGGKAYLDHNSFDYSNTVMRT----- 301
K+D D F L+ + H ++E I + F G L + S S T +RT
Sbjct: 344 PKID---DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
Query: 302 -IKLEHVHFRVFYIQQDKIYLL----------LTKMDI------ENLTISNAQMPHMLFP 344
+ L H + + ++KI + L +D+ + LT + +F
Sbjct: 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
Query: 345 NYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETL-SLVSCFANNTPLEHLD 403
Y + +YL N +P L+ L+L L+ + S S F L LD
Sbjct: 461 IYLSYNKYLQLTRNSFA--------LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
Query: 404 LSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLP----------KSIQILDLNNN 453
LS N + + ND+ E + ++L +N L+ P + IL+L +N
Sbjct: 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESN 572
Query: 454 QIQTVPKETIH-LMALRELNIAFNFLTDLPGCSHFSRLSV--LNIEMNFILSPSLD-FVQ 509
+P E L L+ +++ N L LP +++S+ LN++ N I S F
Sbjct: 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
Query: 510 SCQEVKTLNAGRNPFRCTCE----LKNFIQLETYSEVMMVGWSDSYTCEYPLNLRG---- 561
+ + + L+ NPF CTCE N+I ET++ + + S Y C P + G
Sbjct: 633 AFRNLTELDMRFNPFDCTCESIAWFVNWIN-ETHTNIPEL--SSHYLCNTPPHYHGFPVR 689
Query: 562 ----TRLKDVHLHEL--SCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQ 615
+ KD EL NT++L++ I +++L+ HF+ W + +
Sbjct: 690 LFDTSSCKDSAPFELFFMINTSILLIFIFIVLLI----------HFE-GWRISFYWNVSV 738
Query: 616 TWHRVRKTTQ-EQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDP 674
HRV + ++ + A+I ++ D WV E ++EKED S+ CL E F+
Sbjct: 739 --HRVLGFKEIDRQTEQFEYAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEA 795
Query: 675 GKSISENIVSFIEKSYKSIFVLSPNFVQNEWC-HYEFYFAHHNLFHENSDHIILILLEPI 733
G E IV+ I++S K IFV++ + +++ C ++ + A +N D IIL+ LE I
Sbjct: 796 GVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEI 855
Query: 734 PFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAI 775
P Y + + + + L WP + + G F L+ A+
Sbjct: 856 PDYKLNHALCLRRGMFKSHCILNWPVQKERIGAFRHKLQVAL 897
>gi|7706093 toll-like receptor 7 [Homo sapiens]
Length = 1049
Score = 133 bits (335), Expect = 6e-31
Identities = 185/784 (23%), Positives = 334/784 (42%), Gaps = 92/784 (11%)
Query: 58 NLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTW---- 113
N Q+ + F ++++L+VL L N +Q + + F+ +L+ LDLS N L
Sbjct: 276 NSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAKF 335
Query: 114 -YLLAGLRYLDLSFNDFD------TMPICEEAGNMSHLEILGLSGAKIQK---------S 157
+ L L LDLSFN F+ +M + + ++ L+IL + G ++
Sbjct: 336 LHFLPSLIQLDLSFN-FELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLH 394
Query: 158 DFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKIL 217
+ Q + L L T F+ L +++ + ++ + P + V +TS
Sbjct: 395 NLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNARTSVES 454
Query: 218 EMTNIDGKSQFVSYEMQ-RNLSLENAKTSVLLLNK--------VDLLWDDLFLILQFVWH 268
+ + + Y+ R+ +N + S + +N+ +DL + +F FV
Sbjct: 455 YEPQVLEQLHYFRYDKYARSCRFKNKEASFMSVNESCYKYGQTLDLSKNSIF----FVKS 510
Query: 269 TSVEHFQ----------IRNVTFGGKAY---LDHNSFDYSNTVMRTIKLEHVHFRVFYIQ 315
+ +H + + T G + + D+SN +L+ +H F
Sbjct: 511 SDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNN-----RLDLLHSTAF--- 562
Query: 316 QDKIYLLLTKMDIENLTISNAQMPHML-FPNYPTKFQYLNFANNILTDELFKRTIQLPHL 374
++ L + + + + + HML F Q L +N ++ RT++ L
Sbjct: 563 EELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSST-SRTMESESL 621
Query: 375 KTLILNGNKLETL------SLVSCFANNTPLEHLDLSQNLLQH-KNDENCSWPETVVNMN 427
+TL GN L+ L + F N LE LD+S+N L + P + N++
Sbjct: 622 RTLEFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLS 681
Query: 428 LSYNKLSDSVFRCLP--KSIQILDLNNNQIQTVPKETIHLM-ALRELNIAFNFLTDLPG- 483
L+ N L ++ L K+++ LDL++NQ+ TVP+ + +L+ L + N + L
Sbjct: 682 LAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKY 741
Query: 484 -CSHFSRLSVLNIEMNFI-LSPSLDFVQSC-QEVKTLNAGRNPFRCTCELKNFIQLETYS 540
+L L++ N I + F ++ +K L N F CTC+ F+ ++
Sbjct: 742 FLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVNHT 801
Query: 541 EVMMVGWSDSYTCEYPLNLRGTRLKDVHLH--ELSCNTALLIVTIVVIMLVLGLAVAFCC 598
EV + + TC P +G + + L+ EL +L + + L L + +
Sbjct: 802 EVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASH 861
Query: 599 LHFDLPWYLRMLGQCTQTWHRVR---KTTQEQLKRNVRFHAFISYSEHDSL---WVKNEL 652
L+F WY+ +H + K Q + + + AFI Y D WV EL
Sbjct: 862 LYFWDVWYI---------YHFCKAKIKGYQRLISPDCCYDAFIVYDTKDPAVTEWVLAEL 912
Query: 653 IPNLEK-EDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFY 711
+ LE + +CL E + PG+ + EN+ I+ S K++FV++ + + E FY
Sbjct: 913 VAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFY 972
Query: 712 FAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANL 771
+H L E D IILI LE PF +++ +L+ L + LEWP + + FW L
Sbjct: 973 LSHQRLMDEKVDVIILIFLEK-PFQ--KSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCL 1029
Query: 772 RAAI 775
+ A+
Sbjct: 1030 KNAL 1033
Score = 54.3 bits (129), Expect = 4e-07
Identities = 72/244 (29%), Positives = 112/244 (45%), Gaps = 16/244 (6%)
Query: 52 TLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQ-LDLKTFEFNKELRYLDLSNNR--- 107
TLDLS N +F ++SSDF +S L+ L L N I Q L+ F+ ELRYLD SNNR
Sbjct: 497 TLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDL 556
Query: 108 LKSVTWYLLAGLRYLDLSFND--FDTMPICEEAG---NMSHLEILGLSGAKIQKSDFQKI 162
L S + L L LD+S N F + I N+ L+ L ++ I S + +
Sbjct: 557 LHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTM 616
Query: 163 AHLHLNTV-FLGFRTLPHYEEGSLPIL----NTTKLHIVLPMDTNFWVLLRDGIKTSKIL 217
L T+ F G + EG L N KL L + N L G+
Sbjct: 617 ESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLE-ELDISKNSLSFLPSGVFDGMPP 675
Query: 218 EMTNID-GKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQI 276
+ N+ K+ S+ ++ L+N +T L N++ + + L + + + +++ QI
Sbjct: 676 NLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQI 735
Query: 277 RNVT 280
R++T
Sbjct: 736 RSLT 739
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
Query: 26 EERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQ 85
EE ++ N + V + P L L+ N L + L L L HN++
Sbjct: 653 EELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLT 712
Query: 86 QLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAG---LRYLDLSFN 127
+ + ++ L+ L L NN+++S+T Y L LRYLDLS N
Sbjct: 713 TVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSN 757
Score = 37.7 bits (86), Expect = 0.043
Identities = 22/60 (36%), Positives = 36/60 (60%)
Query: 52 TLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSV 111
TLDLS+N L + + L+ LIL +N+I+ L + +LRYLDLS+N+++ +
Sbjct: 703 TLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMI 762
Score = 33.1 bits (74), Expect = 1.1
Identities = 40/187 (21%), Positives = 78/187 (41%), Gaps = 21/187 (11%)
Query: 27 ERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVL--------- 77
+ ++ +C++ L ++P + TT L L+ N + + + FH + L +
Sbjct: 44 KNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVPI 103
Query: 78 ------ILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDT 131
+C R+ Q+ ++F L+ L L N+L + L L+ L L N+ +
Sbjct: 104 PLGSKNNMCIKRL-QIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFS 162
Query: 132 MPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTT 191
+ E ++++EIL L Q ++ ++ + F L + SL N T
Sbjct: 163 IR-KENLTELANIEILYLG----QNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVT 217
Query: 192 KLHIVLP 198
+ VLP
Sbjct: 218 AVPTVLP 224
Score = 30.0 bits (66), Expect = 9.0
Identities = 45/175 (25%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query: 371 LPHLKTLILNGNKL--------ETLSLVSCFANN---TPLEHLDLSQNLLQHKNDENCSW 419
L +LK+L L+GN+L +L L+S ANN E+L N+ +NC +
Sbjct: 126 LTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLGQNCYY 185
Query: 420 PETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLT 479
+SY+ + F L K +++L L +N + VP T+ L EL + N +
Sbjct: 186 RNPCY---VSYS-IEKDAFLNLTK-LKVLSLKDNNVTAVP--TVLPSTLTELYLYNNMIA 238
Query: 480 DL--PGCSHFSRLSVLNIEMNFILSPSLDF-VQSCQEVKTLNAGRNPFRCTCELK 531
+ ++ ++L +L++ N + F C+ L N F ELK
Sbjct: 239 KIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALTELK 293
>gi|8394456 toll-like receptor 9 isoform A precursor [Homo sapiens]
Length = 1032
Score = 94.4 bits (233), Expect = 4e-19
Identities = 173/767 (22%), Positives = 312/767 (40%), Gaps = 80/767 (10%)
Query: 62 QLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRL-----KSVTWYLL 116
QL F +S+L L+L + + L+ F LR LDLS N L K+ + L
Sbjct: 274 QLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGL 333
Query: 117 AGLRYLDLSFN-----DFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVF 171
LR L+LSFN F + + G++ L+ L + G + D T
Sbjct: 334 TQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLD---------ETTL 384
Query: 172 LGFRTLPHYEEGSLPI--LNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQF- 228
LP + L + +N +L I +V L D + S E+T G++
Sbjct: 385 RPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDN-RISGASELTATMGEADGG 443
Query: 229 ---------VSYEMQRNLSLENAKTSVLLLN-KVDLLWDDLFLILQFVWHTSVEHFQIRN 278
++ S E+ + + LN +DL ++L + Q + H Q
Sbjct: 444 EKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTV-QPEMFAQLSHLQCLR 502
Query: 279 VTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQM 338
++ + + S T ++ + L H +++ + + L +++ +L+ ++
Sbjct: 503 LSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYH---EHSFTELPRLEALDLSYNSQPF 559
Query: 339 P------HMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKL-----ETL 387
+ F + ++L+ A+N + ++ ++ L+ L +GN L E
Sbjct: 560 GMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTS-LRALDFSGNALGHMWAEGD 618
Query: 388 SLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNM--NLSYNKLSDSVF------- 438
+ F + L LDLSQN L + P+T+ N+ +L +L D+
Sbjct: 619 LYLHFFQGLSGLIWLDLSQNRL------HTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWS 672
Query: 439 -RCLPKSIQILDLNNNQIQTVPKETIHL-MALRELNIAFNFLTDL-PGC-SHFSRLSVLN 494
LPK +++LDL NQ++ + ++ LR L+++ N ++ + PG S L LN
Sbjct: 673 LHFLPK-LEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELN 731
Query: 495 IEMNFILSPSLD-FVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTC 553
+ N + + F ++ L+ NP C C F+ + + G C
Sbjct: 732 LSANALKTVDHSWFGPLASALQILDVSANPLHCACGAA-FMDFLLEVQAAVPGLPSRVKC 790
Query: 554 EYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQC 613
P L+G + L L + AL + +L + L + LH W L
Sbjct: 791 GSPGQLQGLSIFAQDLR-LCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHL 849
Query: 614 TQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSL---WVKNELIPNLEKEDG--SILICLY 668
W R + + + + AF+ + + S WV NEL LE+ G ++ +CL
Sbjct: 850 CLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLE 909
Query: 669 ESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILI 728
E + PGK++ EN+ + + S K++FVL+ + F A L + D ++L+
Sbjct: 910 ERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLV 969
Query: 729 LLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAI 775
+L P +RY +L+ L +++ L WP FWA L A+
Sbjct: 970 ILSPDG---RRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMAL 1013
Score = 43.9 bits (102), Expect = 6e-04
Identities = 54/199 (27%), Positives = 81/199 (40%), Gaps = 35/199 (17%)
Query: 23 ELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHN 82
+ P + NCS ++ TLDLS N L +Q F +S L+ L L HN
Sbjct: 459 DTPSSEDFRPNCSTLNF------------TLDLSRNNLVTVQPEMFAQLSHLQCLRLSHN 506
Query: 83 RIQQ-LDLKTFEFNKELRYLDLSNNRL---KSVTWYLLAGLRYLDLSFND--FDTMPICE 136
I Q ++ F L+ LDLS+N+L ++ L L LDLS+N F +
Sbjct: 507 CISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGH 566
Query: 137 EAGNMSHLEI---LGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPH-YEEGSLPI----- 187
++HL L L+ I Q++ L + L H + EG L +
Sbjct: 567 NFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQG 626
Query: 188 --------LNTTKLHIVLP 198
L+ +LH +LP
Sbjct: 627 LSGLIWLDLSQNRLHTLLP 645
Score = 38.9 bits (89), Expect = 0.019
Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Query: 48 PATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNR 107
P LDL+ N L L + + ++LR L + N I + F KELR L+LS N
Sbjct: 677 PKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANA 736
Query: 108 LKSV--TWY--LLAGLRYLDLSFN 127
LK+V +W+ L + L+ LD+S N
Sbjct: 737 LKTVDHSWFGPLASALQILDVSAN 760
Score = 35.0 bits (79), Expect = 0.28
Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 19/109 (17%)
Query: 38 SLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVL----------------ILCH 81
+L VP +L + L LSYN + +L D +++ LRVL + C
Sbjct: 210 NLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECP 269
Query: 82 NRIQQLDLKTFEFNKELRYLDLSNNRLK--SVTWYL-LAGLRYLDLSFN 127
QL TF L L L ++ L + +W+ L LR LDLS N
Sbjct: 270 RHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSEN 318
Score = 33.9 bits (76), Expect = 0.62
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 4/79 (5%)
Query: 53 LDLSYNLLFQLQSSDFHSVSK-LRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSV 111
LDLS N L L ++ K L+VL L N + + F +L LDL+ N+LK++
Sbjct: 633 LDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKAL 692
Query: 112 T-WYLLAG--LRYLDLSFN 127
T L AG LR LD+S N
Sbjct: 693 TNGSLPAGTRLRRLDVSCN 711
Score = 30.8 bits (68), Expect = 5.3
Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 12/128 (9%)
Query: 33 NCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLIL---------CHNR 83
N S ++ VPA L + +L LS+ + L S+ + LR L + C
Sbjct: 129 NLSYNNIMTVPA-LPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQA 187
Query: 84 IQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSH 143
++ L +L L N L V L + L YL LS+N + E+ N++
Sbjct: 188 LEVAPGALLGLGN-LTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKL-APEDLANLTA 245
Query: 144 LEILGLSG 151
L +L + G
Sbjct: 246 LRVLDVGG 253
Score = 30.0 bits (66), Expect = 9.0
Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 23/200 (11%)
Query: 345 NYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDL 404
N P+ +YL + N + + L L+ L + GN ++ P ++
Sbjct: 217 NLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRR--------CDHAPNPCMEC 268
Query: 405 SQNLLQHKND--ENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQ---TVP 459
++ Q D + S E +V + S + L+ S FR L ++++LDL+ N + T
Sbjct: 269 PRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLG-NLRVLDLSENFLYKCITKT 327
Query: 460 KETIHLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLD----FVQSCQEVK 515
K L LR+LN++FN+ + F+ LS+ + + LD F +S E
Sbjct: 328 KAFQGLTQLRKLNLSFNYQKRV----SFAHLSLAPSFGSLVALKELDMHGIFFRSLDETT 383
Query: 516 TLNAGRNPFRCTCELK-NFI 534
R P T L+ NFI
Sbjct: 384 LRPLARLPMLQTLRLQMNFI 403
>gi|167555127 CD180 molecule [Homo sapiens]
Length = 661
Score = 74.7 bits (182), Expect = 3e-13
Identities = 154/654 (23%), Positives = 256/654 (39%), Gaps = 98/654 (14%)
Query: 24 LPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNR 83
+ +E NC N+ L ++P L T L+ S+N L + + F + L L L +
Sbjct: 29 IEKEANKTYNCENLGLSEIPDTLPNTTEFLEFSFNFLPTIHNRTFSRLMNLTFLDLTRCQ 88
Query: 84 IQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAG---LRYLDL---SFNDFDTMPICEE 137
I + TF+ + +L L L+ N L + L G L++L L ++ + +P+
Sbjct: 89 INWIHEDTFQSHHQLSTLVLTGNPLIFMAETSLNGPKSLKHLFLIQTGISNLEFIPV--- 145
Query: 138 AGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFR-TLPHYEEGSLPILNTTKLHIV 196
N+ +LE L L I F K N L F+ HY +++
Sbjct: 146 -HNLENLESLYLGSNHISSIKFPKDFPAR-NLKVLDFQNNAIHYISREDMRSLEQAINLS 203
Query: 197 LPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLS-----LENAKTSVLLLNK 251
L + N + G S I + N G NLS L+N+ T L L
Sbjct: 204 LNFNGNNVKGIELGAFDSTIFQSLNFGGTP---------NLSVIFNGLQNSTTQSLWLGT 254
Query: 252 VDLLWDD--LFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHF 309
+ + D+ +L+ + SVE ++ F + F T ++ + L H
Sbjct: 255 FEDIDDEDISSAMLKGLCEMSVESLNLQEHRFSDISSTTFQCF----TQLQELDLTATHL 310
Query: 310 RVFYIQQDKIYLL----LTKMDIENL-TISNAQMP---HMLFPNYPTKFQY----LNFAN 357
+ + LL L+ + L IS A P H+ K L
Sbjct: 311 KGLPSGMKGLNLLKKLVLSVNHFDQLCQISAANFPSLTHLYIRGNVKKLHLGVGCLEKLG 370
Query: 358 NILTDELFKRTIQ-----------LPHLKTLILNGN--------------KLETLSLV-- 390
N+ T +L I+ L HL+TL L+ N +LE L L
Sbjct: 371 NLQTLDLSHNDIEASDCCSLQLKNLSHLQTLNLSHNEPLGLQSQAFKECPQLELLDLAFT 430
Query: 391 --------SCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFR--- 439
S F N L+ L+L+ L N + + ++NL N D
Sbjct: 431 RLHINAPQSPFQNLHFLQVLNLTYCFLDTSNQHLLAGLPVLRHLNLKGNHFQDGTITKTN 490
Query: 440 --CLPKSIQILDLNNNQIQTVPKETIH-LMALRELNIAFNFLT--DLPGCSHFSRLSVLN 494
S+++L L++ + ++ ++ H L + ++++ N LT + SH + LN
Sbjct: 491 LLQTVGSLEVLILSSCGLLSIDQQAFHSLGKMSHVDLSHNSLTCDSIDSLSHLKGI-YLN 549
Query: 495 IEMNF--ILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSE-VMMVGWSDSY 551
+ N I+SP L + S Q T+N NP CTC +F L Y E + + S+
Sbjct: 550 LAANSINIISPRLLPILSQQ--STINLSHNPLDCTCSNIHF--LTWYKENLHKLEGSEET 605
Query: 552 TCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPW 605
TC P +LRG +L DV +LSC + + +++ L+L + F + + L W
Sbjct: 606 TCANPPSLRGVKLSDV---KLSCGITAIGIFFLIVFLLLLAILLFFAVKYLLRW 656
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/486 (23%), Positives = 206/486 (42%), Gaps = 69/486 (14%)
Query: 25 PEERELM-TNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNR 83
P+ R L+ +CS++ L ++P++L+ T+ LDLS N + QL + S+ L L L N
Sbjct: 42 PDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNA 101
Query: 84 IQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLD---LSFNDFDTMPICEEAG- 139
+ + F L+ L L NN+L+ V L LR L L N +P +G
Sbjct: 102 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL 161
Query: 140 -NMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLG-FRTLPHYEEGSLPILNTTKLHIVL 197
++ HL + + +I F+ ++ L T+ L +P Y G+L L LH+
Sbjct: 162 HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSL--VVLHLHN 219
Query: 198 PMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWD 257
+ DG+ + + L++ N + +F + +L N K N + + +
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDL-NYNNLDEFPT----AIRTLSNLKELGFHSNNIRSIPE 274
Query: 258 DLFLILQFVWHTSV--EHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQ 315
FV + S+ HF + F G++ H +RT+ L Q
Sbjct: 275 K-----AFVGNPSLITIHFYDNPIQFVGRSAFQH------LPELRTLTLNGAS------Q 317
Query: 316 QDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTI--QLPH 373
+ L ++E+LT++ AQ+ + +T+ QLP+
Sbjct: 318 ITEFPDLTGTANLESLTLTGAQISSL------------------------PQTVCNQLPN 353
Query: 374 LKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKL 433
L+ L L+ N LE L F+ L+ +DL N + + ++ ++NL++NK+
Sbjct: 354 LQVLDLSYNLLEDL---PSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKI 410
Query: 434 S---DSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNF-LTDLPGCSHFSR 489
+ + F LP I+ LDL++N + + P +H L L + N L L +F
Sbjct: 411 AIIHPNAFSTLPSLIK-LDLSSNLLSSFPITGLH--GLTHLKLTGNHALQSLISSENFPE 467
Query: 490 LSVLNI 495
L V+ +
Sbjct: 468 LKVIEM 473
Score = 37.7 bits (86), Expect = 0.043
Identities = 48/241 (19%), Positives = 95/241 (39%), Gaps = 38/241 (15%)
Query: 289 HNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPT 348
H+ DY+ + ++ + H+H + K + L ++ +L +N +PT
Sbjct: 199 HHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLD-------EFPT 251
Query: 349 KFQYLN------FANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHL 402
+ L+ F +N + K + P L T+ N ++ F + +HL
Sbjct: 252 AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQ-------FVGRSAFQHL 304
Query: 403 DLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKET 462
+ L + + +P+ NL + L L QI ++P+
Sbjct: 305 PELRTLTLNGASQITEFPDLTGTANL-----------------ESLTLTGAQISSLPQTV 347
Query: 463 IH-LMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGR 521
+ L L+ L++++N L DLP S +L +++ N I +D Q +++LN
Sbjct: 348 CNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAW 407
Query: 522 N 522
N
Sbjct: 408 N 408
>gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens]
Length = 522
Score = 63.2 bits (152), Expect = 1e-09
Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 3/124 (2%)
Query: 31 MTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFH-SVSKLRVLILCHNRIQQLDL 89
+ +C+N +L KVP +L LDLSYN + L S S +KL LIL HN I +
Sbjct: 51 IVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSIST 110
Query: 90 KTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLD--LSFNDFDTMPICEEAGNMSHLEIL 147
+F L+ LDLS+N+LK+V + L+ L+ L +N+ + G +S L+ L
Sbjct: 111 GSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKL 170
Query: 148 GLSG 151
LSG
Sbjct: 171 YLSG 174
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 47 TPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNN 106
TP LDLS N L ++++ F + L VL+L +N I LD F +L+ L LS N
Sbjct: 116 TPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGN 175
Query: 107 RLKS------VTWYLLAGLRYLDLSFNDFDTMPI 134
L V + LA L +LD+S+N +MP+
Sbjct: 176 FLTQFPMDLYVGRFKLAELMFLDVSYNRIPSMPM 209
Score = 45.8 bits (107), Expect = 2e-04
Identities = 58/206 (28%), Positives = 91/206 (44%), Gaps = 36/206 (17%)
Query: 369 IQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNL 428
+ L TLIL N + ++S S F+ L+ LDLS N L+ TV N
Sbjct: 90 VSFAKLNTLILRHNNITSISTGS-FSTTPNLKCLDLSSNKLK-----------TVKN--- 134
Query: 429 SYNKLSDSVFRCLPKSIQILDLNNNQIQTV-PKETIHLMALRELNIAFNFLTDLP----- 482
+VF+ L K +++L L NN I + P L L++L ++ NFLT P
Sbjct: 135 -------AVFQEL-KVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMDLYV 186
Query: 483 GCSHFSRLSVLNIEMNFILSPSLDFVQSC--QEVKTLNAGRNPFRCTCELKN---FIQLE 537
G + L L++ N I S + + ++++ + NPF C C L + F
Sbjct: 187 GRFKLAELMFLDVSYNRIPSMPMHHINLVPGKQLRGIYLHGNPFVCDCSLYSLLVFWYRR 246
Query: 538 TYSEVMMVGWSDSYTCEYPLNLRGTR 563
+S VM + + YTC + R +R
Sbjct: 247 HFSSVM--DFKNDYTCRLWSDSRHSR 270
>gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens]
Length = 522
Score = 63.2 bits (152), Expect = 1e-09
Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 3/124 (2%)
Query: 31 MTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFH-SVSKLRVLILCHNRIQQLDL 89
+ +C+N +L KVP +L LDLSYN + L S S +KL LIL HN I +
Sbjct: 51 IVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSIST 110
Query: 90 KTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLD--LSFNDFDTMPICEEAGNMSHLEIL 147
+F L+ LDLS+N+LK+V + L+ L+ L +N+ + G +S L+ L
Sbjct: 111 GSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKL 170
Query: 148 GLSG 151
LSG
Sbjct: 171 YLSG 174
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 47 TPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNN 106
TP LDLS N L ++++ F + L VL+L +N I LD F +L+ L LS N
Sbjct: 116 TPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGN 175
Query: 107 RLKS------VTWYLLAGLRYLDLSFNDFDTMPI 134
L V + LA L +LD+S+N +MP+
Sbjct: 176 FLTQFPMDLYVGRFKLAELMFLDVSYNRIPSMPM 209
Score = 45.8 bits (107), Expect = 2e-04
Identities = 58/206 (28%), Positives = 91/206 (44%), Gaps = 36/206 (17%)
Query: 369 IQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNL 428
+ L TLIL N + ++S S F+ L+ LDLS N L+ TV N
Sbjct: 90 VSFAKLNTLILRHNNITSISTGS-FSTTPNLKCLDLSSNKLK-----------TVKN--- 134
Query: 429 SYNKLSDSVFRCLPKSIQILDLNNNQIQTV-PKETIHLMALRELNIAFNFLTDLP----- 482
+VF+ L K +++L L NN I + P L L++L ++ NFLT P
Sbjct: 135 -------AVFQEL-KVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMDLYV 186
Query: 483 GCSHFSRLSVLNIEMNFILSPSLDFVQSC--QEVKTLNAGRNPFRCTCELKN---FIQLE 537
G + L L++ N I S + + ++++ + NPF C C L + F
Sbjct: 187 GRFKLAELMFLDVSYNRIPSMPMHHINLVPGKQLRGIYLHGNPFVCDCSLYSLLVFWYRR 246
Query: 538 TYSEVMMVGWSDSYTCEYPLNLRGTR 563
+S VM + + YTC + R +R
Sbjct: 247 HFSSVM--DFKNDYTCRLWSDSRHSR 270
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 62.8 bits (151), Expect = 1e-09
Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 17/112 (15%)
Query: 17 AEGDAPELPEEREL-----------------MTNCSNMSLRKVPADLTPATTTLDLSYNL 59
A G PE+P++R+ + CS++ L KVP DL P TT LDL N
Sbjct: 33 ASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNK 92
Query: 60 LFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSV 111
+ +++ DF ++ L LIL +N+I ++ F +L L LS N+LK +
Sbjct: 93 ITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 62.8 bits (151), Expect = 1e-09
Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 17/112 (15%)
Query: 17 AEGDAPELPEEREL-----------------MTNCSNMSLRKVPADLTPATTTLDLSYNL 59
A G PE+P++R+ + CS++ L KVP DL P TT LDL N
Sbjct: 33 ASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNK 92
Query: 60 LFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSV 111
+ +++ DF ++ L LIL +N+I ++ F +L L LS N+LK +
Sbjct: 93 ITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL 144
>gi|31542244 leucine rich repeat and fibronectin type III domain
containing 5 [Homo sapiens]
Length = 719
Score = 62.8 bits (151), Expect = 1e-09
Identities = 76/258 (29%), Positives = 111/258 (43%), Gaps = 46/258 (17%)
Query: 342 LFPNYPTKFQYLNFAN--NILTDELFKRTIQL--PH-------LKTLILNGNKLETLSLV 390
L N+ T + +FAN +++ L + TI PH L+ L LN N+L ++
Sbjct: 58 LADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITN- 116
Query: 391 SCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPK--SIQIL 448
F+ + L HL L+ N L + + ++LSYN L + + K S+ L
Sbjct: 117 DMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTL 176
Query: 449 DLNNNQIQTVPKETI-HLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDF 507
L++N I +PK T HL + L++ N L LP F R VL + I+SPS
Sbjct: 177 SLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVL--ATSGIISPS--- 231
Query: 508 VQSCQEVKTLNAGRNPFRCTCE------LKNFIQLET-YSEVMMVG---WS---DSYTCE 554
L+ G NP C CE L LET S ++ G WS + + CE
Sbjct: 232 ------TFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCE 285
Query: 555 YPLNLRGTRLKDVHLHEL 572
PL R H HE+
Sbjct: 286 PPLITR-------HTHEM 296
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 28/167 (16%)
Query: 30 LMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDL 89
L T C+ L VP ++ T L L+ N + ++ DF +++ L L L N I +
Sbjct: 33 LATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITP 92
Query: 90 KTFEFNKELRYLDLSNNRLKSVTWYLLAG---------------------------LRYL 122
F + LR L L++NRL +T + +G L L
Sbjct: 93 HAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEEL 152
Query: 123 DLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNT 169
DLS+N+ +T+P + M L L L I +HLH T
Sbjct: 153 DLSYNNLETIP-WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMT 198
Score = 34.3 bits (77), Expect = 0.48
Identities = 20/63 (31%), Positives = 31/63 (49%)
Query: 49 ATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRL 108
A LDLSYN L + + L L L HN I + TF ++ LD+++N+L
Sbjct: 148 ALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKL 207
Query: 109 KSV 111
+ +
Sbjct: 208 QKL 210
>gi|38454322 adhesion molecule with Ig-like domain 3 [Homo sapiens]
Length = 504
Score = 61.2 bits (147), Expect = 4e-09
Identities = 59/190 (31%), Positives = 91/190 (47%), Gaps = 13/190 (6%)
Query: 31 MTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLK 90
+ +C+ + L+ VPA+L AT LDLS+N L +L+ + +LR L L HN + L
Sbjct: 44 LLSCTGLGLQDVPAELPAATADLDLSHNALQRLRPGWLAPLFQLRALHLDHNELDALGRG 103
Query: 91 TFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLD--LSFNDFDTMPICEEAGN----MSHL 144
F LR LDLS+N L+++ + L GL L+ L FN+ + + E A + +SHL
Sbjct: 104 VFVNASGLRLLDLSSNTLRALGRHDLDGLGALEKLLLFNN-RLVHLDEHAFHGLRALSHL 162
Query: 145 EILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHY---EEGSLPILNTTKLHI---VLP 198
+ A ++ HL T+ L L H E +LP L++ LP
Sbjct: 163 YLGCNELASFSFDHLHGLSATHLLTLDLSSNRLGHISVPELAALPAFLKNGLYLHNNPLP 222
Query: 199 MDTNFWVLLR 208
D + LL+
Sbjct: 223 CDCRLYHLLQ 232
>gi|72534676 leucine rich repeat containing 17 isoform 1 [Homo
sapiens]
Length = 441
Score = 60.8 bits (146), Expect = 5e-09
Identities = 35/92 (38%), Positives = 51/92 (55%)
Query: 33 NCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTF 92
+C L+KVP ++ P LDLSYN + QL+ +F V +L+ L L N I+ +D F
Sbjct: 253 DCKRKELKKVPNNIPPDIVKLDLSYNKINQLRPKEFEDVHELKKLNLSSNGIEFIDPAAF 312
Query: 93 EFNKELRYLDLSNNRLKSVTWYLLAGLRYLDL 124
L LDLSNN L++ + +L L +L L
Sbjct: 313 LGLTHLEELDLSNNSLQNFDYGVLEDLYFLKL 344
Score = 43.9 bits (102), Expect = 6e-04
Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 28/160 (17%)
Query: 419 WPETVVNMNLSYNK---LSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAF 475
WP+ +++M L+ NK L +++F K ++ LDL N+I + E
Sbjct: 79 WPQDLLHMLLARNKIRTLKNNMFSKF-KKLKSLDLQQNEISKIESEAF---------FGL 128
Query: 476 NFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQ 535
N LT L +++ VL E+ FI +P L +++ NP+ CTCE++ I
Sbjct: 129 NKLTTL--LLQHNQIKVLTEEV-FIYTPLLSYLRLYD---------NPWHCTCEIETLIS 176
Query: 536 LETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCN 575
+ +G + CE P + +L+ + +L CN
Sbjct: 177 MLQIPRNRNLG--NYAKCESPQEQKNKKLRQIKSEQL-CN 213
Score = 38.5 bits (88), Expect = 0.025
Identities = 20/55 (36%), Positives = 33/55 (60%)
Query: 52 TLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNN 106
+LDL N + +++S F ++KL L+L HN+I+ L + F + L YL L +N
Sbjct: 109 SLDLQQNEISKIESEAFFGLNKLTTLLLQHNQIKVLTEEVFIYTPLLSYLRLYDN 163
>gi|4502403 biglycan preproprotein [Homo sapiens]
Length = 368
Score = 60.8 bits (146), Expect = 5e-09
Identities = 36/130 (27%), Positives = 69/130 (53%), Gaps = 1/130 (0%)
Query: 31 MTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLK 90
+ CS++ L+ VP +++P TT LDL N + +L+ DF + L L+L +N+I ++ K
Sbjct: 73 VVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEK 132
Query: 91 TFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLS 150
F ++L+ L +S N L + L + L L + N +P +G + ++ + +
Sbjct: 133 AFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSG-LRNMNCIEMG 191
Query: 151 GAKIQKSDFQ 160
G ++ S F+
Sbjct: 192 GNPLENSGFE 201
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/77 (33%), Positives = 37/77 (48%)
Query: 35 SNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEF 94
S L +P DL L L +N + ++ D SKL L L HN+I+ ++ + F
Sbjct: 216 SEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF 275
Query: 95 NKELRYLDLSNNRLKSV 111
LR L L NN+L V
Sbjct: 276 LPTLRELHLDNNKLARV 292
>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
sapiens]
Length = 370
Score = 60.8 bits (146), Expect = 5e-09
Identities = 56/171 (32%), Positives = 81/171 (47%), Gaps = 12/171 (7%)
Query: 8 YIFCSIVMTAEGDAPELP-----EERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQ 62
+I C I + A P P + R L +CS + L VP D+ AT TL L N L
Sbjct: 23 WITCWIALYAVEALPTCPFSCKCDSRSLEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSA 82
Query: 63 LQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAG---L 119
L S F ++S L+ L L +N + +L F L L L NN ++++ LL L
Sbjct: 83 LPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLL 142
Query: 120 RYLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSD---FQKIAHLHL 167
R+LDLS N +P G ++ L L L ++Q D F+ +A+L L
Sbjct: 143 RHLDLSINGLAQLPPGLFDGLLA-LRSLSLRSNRLQNLDRLTFEPLANLQL 192
Score = 58.9 bits (141), Expect = 2e-08
Identities = 56/197 (28%), Positives = 89/197 (45%), Gaps = 29/197 (14%)
Query: 375 KTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLS 434
+TL+L NKL L + FAN + L+ LDLS N L ++L
Sbjct: 71 RTLLLLNNKLSALPSWA-FANLSSLQRLDLSNNFL---------------------DRLP 108
Query: 435 DSVFRCLPKSIQILDLNNNQIQTVPKETI-HLMALRELNIAFNFLTDLPGCSHFSRLSVL 493
S+F L + L L NN I+T+ ++ + H LR L+++ N L LP L++
Sbjct: 109 RSIFGDLTNLTE-LQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALR 167
Query: 494 NIEMNFILSPSLDFV--QSCQEVKTLNAGRNPFRCTCELKNFIQ-LETYSEVMMVGWSDS 550
++ + +LD + + ++ L G NP+ C C L+ F +E +S G D
Sbjct: 168 SLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLREFKHWMEWFS--YRGGRLDQ 225
Query: 551 YTCEYPLNLRGTRLKDV 567
C P LRG ++ V
Sbjct: 226 LACTLPKELRGKDMRMV 242
Score = 41.6 bits (96), Expect = 0.003
Identities = 30/74 (40%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 36 NMSLRKVPADL---TPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTF 92
N S+R + DL +P LDLS N L QL F + LR L L NR+Q LD TF
Sbjct: 125 NNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTF 184
Query: 93 EFNKELRYLDLSNN 106
E L+ L + +N
Sbjct: 185 EPLANLQLLQVGDN 198
>gi|40217820 slit and trk like 3 protein [Homo sapiens]
Length = 977
Score = 60.1 bits (144), Expect = 8e-09
Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 50/222 (22%)
Query: 353 LNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHK 412
L+ NN ++ I LP+LK+L LNGN +E L+ F L +L N+++
Sbjct: 437 LHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLT-PGMFRGLQSLHYLYFEFNVIR-- 493
Query: 413 NDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELN 472
++ + F +P ++++L LNNN ++T+P + +L LN
Sbjct: 494 -------------------EIQPAAFSLMP-NLKLLFLNNNLLRTLPTDAFAGTSLARLN 533
Query: 473 IAFNFLTDLPGCSHFSRL-SVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELK 531
+ N+ LP L +++ I++N NP+ CTC+L
Sbjct: 534 LRKNYFLYLPVAGVLEHLNAIVQIDLN----------------------ENPWDCTCDLV 571
Query: 532 NFIQ-LETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHEL 572
F Q +ET S V +VG C P NL ++ + L L
Sbjct: 572 PFKQWIETISSVSVVG---DVLCRSPENLTHRDVRTIELEVL 610
Score = 47.4 bits (111), Expect = 5e-05
Identities = 55/221 (24%), Positives = 87/221 (39%), Gaps = 47/221 (21%)
Query: 353 LNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHK 412
+N NN L D L LK L L+ NKL+ F LE+L N+++
Sbjct: 106 INLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRN-DTFLGLESLEYLQADYNVIK-- 162
Query: 413 NDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELN 472
++ FR L K +++L LN+N I +P ++L L+
Sbjct: 163 -------------------RIESGAFRNLSK-LRVLILNDNLIPMLPTNLFKAVSLTHLD 202
Query: 473 IAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKN 532
+ N RL VL LD + + + L NP+ CTCE+
Sbjct: 203 LRGN------------RLKVL------FYRGMLDHIG--RSLMELQLEENPWNCTCEI-- 240
Query: 533 FIQLETYSE-VMMVGWSDSYTCEYPLNLRGTRLKDVHLHEL 572
+QL+++ E + TCE P + G L+++ EL
Sbjct: 241 -VQLKSWLERIPYTALVGDITCETPFHFHGKDLREIRKTEL 280
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/57 (43%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 53 LDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLK 109
L YN++ +++S F ++SKLRVLIL N I L F+ L +LDL NRLK
Sbjct: 154 LQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFK-AVSLTHLDLRGNRLK 209
Score = 38.1 bits (87), Expect = 0.033
Identities = 35/126 (27%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Query: 30 LMTNCSNMSLRKVPADLTPATTT---LDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQ 86
L NC + ++L P L LS NL+ ++ SDF + S L +L L +NRI
Sbjct: 388 LTVNCKERGFNNI-SELLPRPLNAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISY 446
Query: 87 LDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEA--GNMSHL 144
+ F L+ L L+ N ++ +T + GL+ L + +F+ + + A M +L
Sbjct: 447 VQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNL 506
Query: 145 EILGLS 150
++L L+
Sbjct: 507 KLLFLN 512
>gi|21361633 leucine rich repeat containing 40 [Homo sapiens]
Length = 602
Score = 59.7 bits (143), Expect = 1e-08
Identities = 117/522 (22%), Positives = 217/522 (41%), Gaps = 60/522 (11%)
Query: 35 SNMSLRKVPADLT--PATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTF 92
SN L+ + DL PA T LD+ N L L S+ + L+ L + HN+++ L +
Sbjct: 90 SNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLKILPEEIT 148
Query: 93 EFNKELRYLDLSNNRLKSVT--WYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLS 150
+ L+ L L +N L ++ + L+ L LDLS N T+P ++S L L LS
Sbjct: 149 NL-RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPA--SFSSLSSLVRLNLS 205
Query: 151 GAKIQK-----SDFQKIAHLHLNTVFLGFRTLPHYEEG----SLPILNTTKLHIVLPMDT 201
+++ + +++ HL N+ L T+P G L L KL +
Sbjct: 206 SNELKSLPAEINRMKRLKHLDCNSNLL--ETIPPELAGMESLELLYLRRNKLRFL----- 258
Query: 202 NFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWDDLFL 261
+ +L+ ++ G++Q E + L + L NK+ + D++ L
Sbjct: 259 -------PEFPSCSLLKELHV-GENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 310
Query: 262 ILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYL 321
+ S+E + N D +S YS L ++H + ++ + +
Sbjct: 311 L------RSLERLDLSNN--------DISSLPYS--------LGNLHLKFLALEGNPLRT 348
Query: 322 LLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNG 381
+ ++ + + + + P++ + L E + LK L +
Sbjct: 349 IRREIISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIITLKILDYS- 407
Query: 382 NKLETLSLVSCF--ANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSD-SVF 438
+K TL F + + ++ S+N L E V +++LS+NKLS S+
Sbjct: 408 DKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLE 467
Query: 439 RCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLPGCSH-FSRLSVLNIEM 497
C+ + + LDL NN + ++P+E L+ L+ +N++FN LP + L + I
Sbjct: 468 LCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISN 527
Query: 498 NFILSPSLDFVQSCQEVKTLNAGRNP-FRCTCELKNFIQLET 538
N + S ++ + + TL+ N + EL N + L T
Sbjct: 528 NQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRT 569
Score = 53.5 bits (127), Expect = 8e-07
Identities = 94/376 (25%), Positives = 166/376 (44%), Gaps = 52/376 (13%)
Query: 33 NCSNMSLRKVPADLTPATTTLDLSYNLLFQLQS-SDFHSVSKLRVLILCHNRIQQLDLKT 91
+C++ L +P +L +L+L Y +L+ +F S S L+ L + N+I+ L+ +
Sbjct: 226 DCNSNLLETIPPELA-GMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEH 284
Query: 92 FEFNKELRYLDLSNNRLKSV--TWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGL 149
+ + LDL +N+LKSV LL L LDLS ND ++P GN+ HL+ L L
Sbjct: 285 LKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPY--SLGNL-HLKFLAL 341
Query: 150 SGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRD 209
G + ++ ++I V R+ ++G + T+ + LP ++ +
Sbjct: 342 EGNPL-RTIRREIISKGTQEVLKYLRS-KIKDDGPSQSESATETAMTLPSESRVNI---H 396
Query: 210 GIKTSKILEMTNIDG-----------KSQFV-SYEMQRNLSLENAKTSVLL---LNKVDL 254
I T KIL+ ++ KS V S +N E K V L ++ VDL
Sbjct: 397 AIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDL 456
Query: 255 LWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYI 314
++ L I S+E ++ +TF NS + ++ ++ F F +
Sbjct: 457 SFNKLSFI-------SLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKM 509
Query: 315 QQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKR-TIQLP- 372
+ +Y + T +E + ISN Q+ + Q + N+ T +L +Q+P
Sbjct: 510 LPEVLYRIFT---LETILISNNQVGSV-------DPQKMKMMENLTTLDLQNNDLLQIPP 559
Query: 373 ------HLKTLILNGN 382
+L+TL+L+GN
Sbjct: 560 ELGNCVNLRTLLLDGN 575
Score = 31.6 bits (70), Expect = 3.1
Identities = 40/152 (26%), Positives = 62/152 (40%), Gaps = 26/152 (17%)
Query: 448 LDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLPGC-SHFSRLSVLNIEMNFILSPSLD 506
L ++NN++Q++ + L AL L+I N LT LP L LN+ N L +
Sbjct: 87 LIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHN-KLKILPE 145
Query: 507 FVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYP---------- 556
+ + + +K L N C E F QL ++ + S+++ P
Sbjct: 146 EITNLRNLKCLYLQHNELTCISE--GFEQLSNLEDLDL---SNNHLTTVPASFSSLSSLV 200
Query: 557 -LNLRGTRLKDV--------HLHELSCNTALL 579
LNL LK + L L CN+ LL
Sbjct: 201 RLNLSSNELKSLPAEINRMKRLKHLDCNSNLL 232
>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
sapiens]
Length = 581
Score = 59.3 bits (142), Expect = 1e-08
Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 9 IFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDF 68
+ +++ +AE P+ M C + L+++P+ ++ L L YN L +L+ + F
Sbjct: 22 VLLTMLSSAERGCPKGCRCEGKMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQF 81
Query: 69 HSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLK---SVTWYLLAGLRYLDLS 125
+++L L L HN I +D F + L+ L LS+NR+ + T+ + LR LDLS
Sbjct: 82 KGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLS 141
Query: 126 FNDFDTM 132
+N ++
Sbjct: 142 YNQLHSL 148
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/83 (36%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 53 LDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVT 112
LDLSYN L L S F + KL L L N ++ + ++ F+ + L LDL NR++S+
Sbjct: 138 LDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLA 197
Query: 113 WYLLAG---LRYLDLSFNDFDTM 132
+ AG L+ L L N F +
Sbjct: 198 RNVFAGMIRLKELHLEHNQFSKL 220
Score = 37.0 bits (84), Expect = 0.073
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 12/102 (11%)
Query: 38 SLRKVPADLTPATTTL---DLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEF 94
SLR +P + L DL YN + L + F + +L+ L L HN+ +L+L F
Sbjct: 168 SLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPR 227
Query: 95 NKELRYLDLSNNRLK------SVTWYLLAGLRYLDLSFNDFD 130
L+ L L N++ S TW + L+ LDLS N+ +
Sbjct: 228 LVSLQNLYLQWNKISVIGQTMSWTW---SSLQRLDLSGNEIE 266
>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
Length = 541
Score = 57.4 bits (137), Expect = 5e-08
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 23/201 (11%)
Query: 579 LIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFI 638
+I+ +++++ V+ L DL + R H R+ E L + AF+
Sbjct: 331 MIIAVLILVAVVCLVTVCVIYRVDLVLFYR---------HLTRR--DETLTDGKTYDAFV 379
Query: 639 SYSEH------DSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKS 692
SY + + E++P + ++ +C++E PG ++ + I S IEKS +
Sbjct: 380 SYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRL 439
Query: 693 IFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKK 752
I VLS +++ NE YE H E IILI P+ + + K LL+
Sbjct: 440 IIVLSKSYMSNE-VRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLK---LLKSH 495
Query: 753 AYLEWPKDRRKC--GLFWANL 771
L+W D+ FW NL
Sbjct: 496 RVLKWKADKSLSYNSRFWKNL 516
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 56.6 bits (135), Expect = 9e-08
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
Query: 33 NCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTF 92
+C ++LR VP ++ T LDL+ N + ++ +DF + LRVL L N+I ++ F
Sbjct: 40 DCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAF 99
Query: 93 EFNKELRYLDLSNNRLKSVTWYLLAG---LRYLDLSFNDFDTMP 133
+ KEL L L+ N L+ L G L LDLS N +P
Sbjct: 100 QDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIP 143
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 6/123 (4%)
Query: 29 ELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLD 88
+ + CSN L+ +P + T L L N F L + + L ++ L +NRI L
Sbjct: 735 DTVVRCSNKGLKVLPKGIPRDVTELYLDGNQ-FTLVPKELSNYKHLTLIDLSNNRISTLS 793
Query: 89 LKTFEFNKELRYLDLSNNRLKSV---TWYLLAGLRYLDLSFNDFDTMP--ICEEAGNMSH 143
++F +L L LS NRL+ + T+ L LR L L ND +P + +SH
Sbjct: 794 NQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSH 853
Query: 144 LEI 146
L I
Sbjct: 854 LAI 856
Score = 41.6 bits (96), Expect = 0.003
Identities = 62/235 (26%), Positives = 97/235 (41%), Gaps = 32/235 (13%)
Query: 345 NYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDL 404
N P + L+ N +T L HL+ L L NK+ T+ F + LE L L
Sbjct: 52 NIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIER-GAFQDLKELERLRL 110
Query: 405 SQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIH 464
++N LQ +PE + L KL +R LDL+ NQIQ +P++
Sbjct: 111 NRNHLQ-------LFPELLF---LGTAKL----YR--------LDLSENQIQAIPRKAFR 148
Query: 465 -LMALRELNIAFNFLTDL-PGCSHFSR-LSVLNIEMNFILSPSLDFVQSCQEVKTLNAGR 521
+ ++ L + +N ++ + G R L VL + N I S+ +++T
Sbjct: 149 GAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHS 208
Query: 522 NPFRCTCELKNFIQLETYSEVMMVGWSDSYT-CEYPLNLRGTRLKDVHLHELSCN 575
N C C L + + VG YT C P +LRG + +V E C+
Sbjct: 209 NNLYCDCHLAWL--SDWLRQRPRVG---LYTQCMGPSHLRGHNVAEVQKREFVCS 258
Score = 40.0 bits (92), Expect = 0.009
Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 31 MTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLK 90
+ +C L ++P +L T + L N + + F KLR + L +N+I +L
Sbjct: 283 IVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPD 342
Query: 91 TFEFNKELRYLDLSNNRLKSVTWYLLAG---LRYLDLSFNDFDTMPICEEAGNMSHLEIL 147
F+ + L L L N++ + L G L+ L L+ N + + + + ++ +L +L
Sbjct: 343 AFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRV-DAFQDLHNLNLL 401
Query: 148 GLSGAKIQ 155
L K+Q
Sbjct: 402 SLYDNKLQ 409
Score = 39.3 bits (90), Expect = 0.015
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 15/108 (13%)
Query: 377 LILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDS 436
L L+GN+ + +N L +DLS N + ++++ S ++ + LSYN+L
Sbjct: 759 LYLDGNQFTLVPKE--LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRL--- 813
Query: 437 VFRCLP-------KSIQILDLNNNQIQTVPKETIH-LMALRELNIAFN 476
RC+P KS+++L L+ N I VP+ + L AL L I N
Sbjct: 814 --RCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 859
Score = 36.2 bits (82), Expect = 0.13
Identities = 39/190 (20%), Positives = 73/190 (38%), Gaps = 43/190 (22%)
Query: 420 PETVVNMNLSYNKLSDSVFRCLP-------KSIQILDLNNNQIQTVPKETIH-LMALREL 471
PET+ + L N + + +P K ++ +DL+NNQI + + L +L L
Sbjct: 299 PETITEIRLEQNTI-----KVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSL 353
Query: 472 NIAFNFLTDLP--------------------------GCSHFSRLSVLNIEMNFILSPSL 505
+ N +T+LP L++L++ N + + +
Sbjct: 354 VLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK 413
Query: 506 DFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYPLNLRGTRLK 565
+ ++T++ +NPF C C LK L Y + S + C P L R+
Sbjct: 414 GTFSPLRAIQTMHLAQNPFICDCHLK---WLADYLHTNPIETSGA-RCTSPRRLANKRIG 469
Query: 566 DVHLHELSCN 575
+ + C+
Sbjct: 470 QIKSKKFRCS 479
Score = 35.8 bits (81), Expect = 0.16
Identities = 44/204 (21%), Positives = 83/204 (40%), Gaps = 33/204 (16%)
Query: 377 LILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSD- 435
L LN N+ L F L ++ S N + + V + L+ N+L +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 436 --SVFRCLPKSIQILDLNNNQIQTVPKET-IHLMALRELNIAFNFLTDL-PGCSHFSRLS 491
+F+ L +S++ L L +N+I V ++ I L ++R L++ N +T + PG
Sbjct: 598 QHKMFKGL-ESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGA------- 649
Query: 492 VLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSY 551
+ + TLN NPF C C L + ++ + +
Sbjct: 650 ----------------FDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIV----TGNP 689
Query: 552 TCEYPLNLRGTRLKDVHLHELSCN 575
C+ P L+ ++DV + + +C+
Sbjct: 690 RCQKPYFLKEIPIQDVAIQDFTCD 713
Score = 35.4 bits (80), Expect = 0.21
Identities = 30/128 (23%), Positives = 52/128 (40%), Gaps = 28/128 (21%)
Query: 33 NCSNMSLRKVPADLTPATTTLDL-------------------------SYNLLFQLQSSD 67
+CSN L K+P + T L L S N + ++
Sbjct: 518 DCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGA 577
Query: 68 FHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSV---TWYLLAGLRYLDL 124
F S + ++L NR++ + K F+ + L+ L L +NR+ V ++ L+ +R L L
Sbjct: 578 FEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSL 637
Query: 125 SFNDFDTM 132
N T+
Sbjct: 638 YDNQITTV 645
Score = 31.6 bits (70), Expect = 3.1
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Query: 52 TLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSV 111
+L L N + +L S F + L++L+L N+I L + F+ L L L +N+L+++
Sbjct: 352 SLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTI 411
Query: 112 ---TWYLLAGLRYLDLSFNDF 129
T+ L ++ + L+ N F
Sbjct: 412 AKGTFSPLRAIQTMHLAQNPF 432
Score = 30.4 bits (67), Expect = 6.9
Identities = 25/118 (21%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 393 FANNTPLEHLDLSQNLLQHKNDEN-----------CSWPETVVNMNLSYNKLSDSVFRCL 441
F P++ + + ND+N C+ +TVV + NK + + +
Sbjct: 696 FLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCS---NKGLKVLPKGI 752
Query: 442 PKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNF 499
P+ + L L+ NQ VPKE + L ++++ N ++ L S + +L + +++
Sbjct: 753 PRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSY 810
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 56.2 bits (134), Expect = 1e-07
Identities = 34/102 (33%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Query: 34 CSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFE 93
C ++ L VPA + P T+ LDL +N + ++Q F + L L+L +N+I+++ FE
Sbjct: 49 CMHLLLEAVPA-VAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFE 107
Query: 94 FNKELRYLDLSNNRLKSV---TWYLLAGLRYLDLSFNDFDTM 132
+ L+YL L N ++S+ + LA L L L FN +T+
Sbjct: 108 DLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETL 149
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Query: 422 TVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIH-LMALRELNIAFNFLTD 480
T++ N ++ F L ++++ L L N+IQ++ ++ L +L +L + FN +
Sbjct: 90 TLLLNNNQIKRIPSGAFEDL-ENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIET 148
Query: 481 LPGCS--HFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQL-E 537
L S H +L L + N I + +K L N C CE+ L +
Sbjct: 149 LDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLK 208
Query: 538 TYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSC 574
TY+E + CEYP ++G + + EL+C
Sbjct: 209 TYAESGNA--QAAAICEYPRRIQGRSVATITPEELNC 243
Score = 33.9 bits (76), Expect = 0.62
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 15/121 (12%)
Query: 35 SNMSLRKVPADLTPATTTLDLSYNLLFQLQSSD---FHSVSKLRVLILCHNRIQQLDLKT 91
+N ++++P+ L Y ++QS D F ++ L L L N+I+ LD +
Sbjct: 94 NNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDS 153
Query: 92 FEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSH--LEILGL 149
F+ +L L L NNR+ +L+ G +FN ++M N H EIL L
Sbjct: 154 FQHLPKLERLFLHNNRIT----HLVPG------TFNHLESMKRLRLDSNTLHCDCEILWL 203
Query: 150 S 150
+
Sbjct: 204 A 204
>gi|27436867 slit and trk like 4 protein [Homo sapiens]
Length = 837
Score = 56.2 bits (134), Expect = 1e-07
Identities = 63/258 (24%), Positives = 102/258 (39%), Gaps = 40/258 (15%)
Query: 326 MDIENLTISNAQMPHMLFPNYP----TKFQYLNFANNILTDELFKRTIQLPHLKTLILNG 381
+ +EN+ N + + PN + F +LNF NN L + H +L L
Sbjct: 33 VSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGN 92
Query: 382 NKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYN---KLSDSVF 438
NKL+ + F + L+ L L+ N L+ + E + + YN + F
Sbjct: 93 NKLQNIE-GGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAF 151
Query: 439 RCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLP---GCSHFSRLSVLNI 495
L K +++L LN+N I +P +L L+I N + LP H R+ L +
Sbjct: 152 NKLHK-LKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQL 210
Query: 496 EMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVG-WSDSYTCE 554
E NP+ C+C+L + L+ + E M + CE
Sbjct: 211 E------------------------DNPWNCSCDL---LPLKAWLENMPYNIYIGEAICE 243
Query: 555 YPLNLRGTRLKDVHLHEL 572
P +L G LK+ + EL
Sbjct: 244 TPSDLYGRLLKETNKQEL 261
Score = 48.5 bits (114), Expect = 2e-05
Identities = 73/312 (23%), Positives = 120/312 (38%), Gaps = 66/312 (21%)
Query: 330 NLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSL 389
N N Q L P P + L+ N + D L L L N++ T+
Sbjct: 360 NCQEKNIQSMSELIPK-PLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQI-TVIK 417
Query: 390 VSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYN---KLSDSVFRCLPKSIQ 446
F N T L L L+ N ++ E S + + L YN ++S F +P ++Q
Sbjct: 418 GDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMP-NLQ 476
Query: 447 ILDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLD 506
+L LNNN ++++P L LN+ N LP +S LD
Sbjct: 477 LLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLP------------------VSGVLD 518
Query: 507 FVQSCQEVKTLNAGRNPFRCTCELKNF-IQLETYSEVMMVGWSDSYTCEYPLNLRGTRLK 565
+QS ++ + NP+ CTC+L + +E S+ ++V CE P+ LK
Sbjct: 519 QLQSLTQI---DLEGNPWDCTCDLVALKLWVEKLSDGIVV---KELKCETPVQFANIELK 572
Query: 566 DVHLHELSCNTAL----------------------------------LIVTIVVIMLVLG 591
+ +E+ C L +++ ++++L+L
Sbjct: 573 SLK-NEILCPKLLNKPSAPFTSPAPAITFTTPLGPIRSPPGGPVPLSILILSILVVLILT 631
Query: 592 LAVAFCCLHFDL 603
+ VAFC L F L
Sbjct: 632 VFVAFCLLVFVL 643
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
Query: 53 LDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVT 112
L L+ N + +L F + L+ L L +N I+++ TF+ L+ L L+NN LKS+
Sbjct: 430 LYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 489
Query: 113 WYLLAG--LRYLDLSFNDFDTMPICEEAGNMSHLEILGLSG 151
Y+ +G L L+L N F +P+ + L + L G
Sbjct: 490 VYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEG 530
Score = 38.9 bits (89), Expect = 0.019
Identities = 90/388 (23%), Positives = 161/388 (41%), Gaps = 50/388 (12%)
Query: 53 LDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVT 112
L YNL+ ++ F+ + KL+VLIL N I L F F L +LD+ NR++ +
Sbjct: 136 LQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRF-ASLTHLDIRGNRIQKLP 194
Query: 113 WY-LLAGL-RYLDLSFND------FDTMPICEEAGNMSHLEILG---------LSGAKIQ 155
+ +L + R ++L D D +P+ NM + +G L G ++
Sbjct: 195 YIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLK 254
Query: 156 KSDFQKIAHLHLNTVFLGFRTLP--HYEEG-SLPILNTTK--LHIVL---PMDTNFWVLL 207
+++ Q++ + + F R LP E G + P +TT+ LH ++ P TN +
Sbjct: 255 ETNKQELCPMGTGSDF-DVRILPPSQLENGYTTPNGHTTQTSLHRLVTKPPKTTNPSKI- 312
Query: 208 RDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVD--LLWDDLFLILQF 265
GI K L N+ SQ VSY+ + + D L + +Q
Sbjct: 313 -SGIVAGKALSNRNL---SQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQS 368
Query: 266 VWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTK 325
+ + + + G + D + D+ T + L H+ + + ++ LT
Sbjct: 369 MSELIPKPLNAKKLHVNGNSIKDVDVSDF--TDFEGLDLLHLGSNQITVIKGDVFHNLT- 425
Query: 326 MDIENLTISNAQMPHMLFPNYPTKF------QYLNFANNILTDELFKRTIQLPHLKTLIL 379
++ L ++ Q+ + YP F QYL N++ + +P+L+ L L
Sbjct: 426 -NLRRLYLNGNQIERL----YPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYL 480
Query: 380 NGNKLETLSLVSCFANNTPLEHLDLSQN 407
N N L++L + + PL L+L N
Sbjct: 481 NNNLLKSLPVY--IFSGAPLARLNLRNN 506
Score = 35.4 bits (80), Expect = 0.21
Identities = 60/248 (24%), Positives = 105/248 (42%), Gaps = 34/248 (13%)
Query: 25 PEERELMTNCSNMSLRKVPADLTPATTT---LDLSYNLLFQLQSSDFHSVSKLRVLILCH 81
P + L NC +++ + ++L P L ++ N + + SDF L +L L
Sbjct: 352 PSDLGLSVNCQEKNIQSM-SELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGS 410
Query: 82 NRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAG---LRYLDLSFN--------DFD 130
N+I + F LR L L+ N+++ + + +G L+YL L +N FD
Sbjct: 411 NQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFD 470
Query: 131 TMPICE----EAGNMSHLEILGLSGAKIQKSDFQ--KIAHLHLNTVFLGFRTLPHYEEGS 184
+MP + + L + SGA + + + + K +L ++ V ++L +
Sbjct: 471 SMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEG 530
Query: 185 LPILNTTKLHIVLPMDTNFWV-LLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAK 243
P T L + WV L DGI ++ T + QF + E++ SL+N
Sbjct: 531 NPWDCTCDL-----VALKLWVEKLSDGIVVKELKCETPV----QFANIELK---SLKNEI 578
Query: 244 TSVLLLNK 251
LLNK
Sbjct: 579 LCPKLLNK 586
>gi|16418445 leucine rich repeat containing 3B [Homo sapiens]
Length = 259
Score = 55.5 bits (132), Expect = 2e-07
Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Query: 30 LMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDL 89
L CSN +L+++P DL P T L L N + + + F + +LRVL L N I+ +D
Sbjct: 46 LNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDE 105
Query: 90 KTFEFNKE-LRYLDLSNNRLKSV 111
F+ E L+ LDLS+NR++SV
Sbjct: 106 HAFKGVAETLQTLDLSDNRIQSV 128
Score = 30.8 bits (68), Expect = 5.3
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 439 RCLPKSIQILDLNNNQIQTVPKETI-HLMALRELNIAFN---FLTDLPGCSHFSRLSVLN 494
R LP +L L++NQI ++P E L LR LN++ N F+ + L L+
Sbjct: 60 RDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLD 119
Query: 495 IEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQ 535
+ N I S + + + NP+ C C L+ ++
Sbjct: 120 LSDNRIQSVHKNAFNNLK--ARARIANNPWHCDCTLQQVLR 158
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,676,834
Number of Sequences: 37866
Number of extensions: 1249590
Number of successful extensions: 5727
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 3836
Number of HSP's gapped (non-prelim): 1334
length of query: 811
length of database: 18,247,518
effective HSP length: 111
effective length of query: 700
effective length of database: 14,044,392
effective search space: 9831074400
effective search space used: 9831074400
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.