Guide to the Human Genome
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Search of human proteins with 62420884

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62420884 discoidin domain receptor family, member 2
precursor [Homo sapiens]
         (855 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62420886 discoidin domain receptor family, member 2 precursor...  1753   0.0  
gi|62420884 discoidin domain receptor family, member 2 precursor...  1753   0.0  
gi|38327632 discoidin domain receptor family, member 1 isoform b...   921   0.0  
gi|83977450 discoidin domain receptor family, member 1 isoform a...   912   0.0  
gi|83977452 discoidin domain receptor family, member 1 isoform c...   905   0.0  
gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isofo...   253   4e-67
gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isofo...   253   4e-67
gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isofo...   248   2e-65
gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isofo...   244   3e-64
gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isofor...   244   3e-64
gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isofo...   244   3e-64
gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isofo...   238   1e-62
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]    226   7e-59
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo...   212   1e-54
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso...   211   3e-54
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec...   204   2e-52
gi|119395738 insulin receptor isoform Short precursor [Homo sapi...   202   8e-52
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]   202   8e-52
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...   201   2e-51
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...   201   2e-51
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi...   198   2e-50
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]             196   8e-50
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]               196   8e-50
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]             196   8e-50
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]             196   8e-50
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]             196   8e-50
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [...   194   2e-49
gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [...   194   2e-49
gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor [...   194   2e-49
gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor [...   194   2e-49

>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 1753 bits (4540), Expect = 0.0
 Identities = 855/855 (100%), Positives = 855/855 (100%)

Query: 1   MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY 60
           MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
Sbjct: 1   MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY 60

Query: 61  GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI 120
           GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
Sbjct: 61  GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI 120

Query: 121 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV 180
           NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
Sbjct: 121 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV 180

Query: 181 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD 240
           ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
Sbjct: 181 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD 240

Query: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300
           DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
Sbjct: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300

Query: 301 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS 360
           EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
Sbjct: 301 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS 360

Query: 361 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL 420
           EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
Sbjct: 361 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL 420

Query: 421 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD 480
           WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
Sbjct: 421 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD 480

Query: 481 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV 540
           YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
Sbjct: 481 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV 540

Query: 541 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN 600
           PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
Sbjct: 541 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN 600

Query: 601 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG 660
           QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
Sbjct: 601 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG 660

Query: 661 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK 720
           DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
Sbjct: 661 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK 720

Query: 721 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET 780
           NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
Sbjct: 721 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET 780

Query: 781 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP 840
           FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
Sbjct: 781 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP 840

Query: 841 SFQEIHLLLLQQGDE 855
           SFQEIHLLLLQQGDE
Sbjct: 841 SFQEIHLLLLQQGDE 855


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 1753 bits (4540), Expect = 0.0
 Identities = 855/855 (100%), Positives = 855/855 (100%)

Query: 1   MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY 60
           MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
Sbjct: 1   MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY 60

Query: 61  GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI 120
           GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
Sbjct: 61  GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI 120

Query: 121 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV 180
           NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
Sbjct: 121 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV 180

Query: 181 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD 240
           ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
Sbjct: 181 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD 240

Query: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300
           DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
Sbjct: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300

Query: 301 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS 360
           EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
Sbjct: 301 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS 360

Query: 361 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL 420
           EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
Sbjct: 361 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL 420

Query: 421 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD 480
           WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
Sbjct: 421 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD 480

Query: 481 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV 540
           YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
Sbjct: 481 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV 540

Query: 541 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN 600
           PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
Sbjct: 541 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN 600

Query: 601 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG 660
           QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
Sbjct: 601 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG 660

Query: 661 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK 720
           DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
Sbjct: 661 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK 720

Query: 721 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET 780
           NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
Sbjct: 721 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET 780

Query: 781 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP 840
           FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
Sbjct: 781 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP 840

Query: 841 SFQEIHLLLLQQGDE 855
           SFQEIHLLLLQQGDE
Sbjct: 841 SFQEIHLLLLQQGDE 855


>gi|38327632 discoidin domain receptor family, member 1 isoform b
           [Homo sapiens]
          Length = 876

 Score =  921 bits (2381), Expect = 0.0
 Identities = 485/891 (54%), Positives = 599/891 (67%), Gaps = 67/891 (7%)

Query: 5   PRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYG 61
           P  L  L LLL + S     K   +PA CRY LGM    IPD DI+ASS WS+STAA++ 
Sbjct: 3   PEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHS 62

Query: 62  RLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKIN 121
           RL+S +GDGAWCP   V P + +E+LQ+DL  LH + LVGTQGRHAGG G EF+  Y++ 
Sbjct: 63  RLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLR 121

Query: 122 YSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVE 181
           YSRDG RW+ W++R G++V+ GN +P  + LKDL PP+VAR VRF P  D  M+VC+RVE
Sbjct: 122 YSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVE 181

Query: 182 LYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGVSGLD 240
           LYGC+W DGL+SY AP GQ   L     +YLNDS YDG  VG     GLGQL DGV GLD
Sbjct: 182 LYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLD 239

Query: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300
           DF ++ E  VWPGYDYVGW N S ++GY+E+ FEFDR+R F  M+VHCNNM   G ++  
Sbjct: 240 DFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPG 299

Query: 301 EVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMF 359
            V+C FR   A  WE   +   L  +  +P AR V+VPL  R+A  ++C++ FA  W++F
Sbjct: 300 GVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLF 359

Query: 360 SEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDSNTRI 400
           SEI+F SD  + N+S AL    P +P               + P    P+ K + S T I
Sbjct: 360 SEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAI 418

Query: 401 LIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSS 460
           LIGCLVAII +LL II ++LWR  W+++L KA RR+L++E+TV LS+P D+ + NN    
Sbjct: 419 LIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNR--P 476

Query: 461 SPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAP----GEEESGCSGVVKPVQPSGP- 515
            P E              P YQEP R     P  AP    G   SG    ++P +P  P 
Sbjct: 477 GPREP-------------PPYQEP-RPRGNPPHSAPCVPNGSAYSG--DYMEPEKPGAPL 520

Query: 516 ------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKL 569
                   VPHYAEADIV LQGVTGGNTY+VPA+    +      V+ FPR  L FKEKL
Sbjct: 521 LPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRVD-FPRSRLRFKEKL 579

Query: 570 GEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIM 629
           GEGQFGEVHLCEV+  +     DF L+V    P+LVAVK+LR DA KNARNDFLKE+KIM
Sbjct: 580 GEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKIM 639

Query: 630 SRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE---------PPNSSSSDVR 680
           SRLKDPNII LL VC+ DDPLCMIT+YMENGDLNQFLS H+         P +  ++   
Sbjct: 640 SRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGP 699

Query: 681 TVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDY 740
           T+SY  L  +A QIASGM+YL++LNFVHRDLATRNCLVG+N+TIKIADFGMSRNLY+GDY
Sbjct: 700 TISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDY 759

Query: 741 YRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIEN 800
           YR+QGRAVLPIRWM+WE IL+GKFTTASDVWAFGVTLWE    C+ QP+ QL+DEQVIEN
Sbjct: 760 YRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIEN 819

Query: 801 TGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQ 851
            GEFFRDQGRQ YL +P  CP  +Y+LML CW R+++ RP F ++H  L +
Sbjct: 820 AGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAE 870


>gi|83977450 discoidin domain receptor family, member 1 isoform a
           [Homo sapiens]
          Length = 913

 Score =  912 bits (2356), Expect = 0.0
 Identities = 480/910 (52%), Positives = 598/910 (65%), Gaps = 68/910 (7%)

Query: 5   PRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYG 61
           P  L  L LLL + S     K   +PA CRY LGM    IPD DI+ASS WS+STAA++ 
Sbjct: 3   PEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHS 62

Query: 62  RLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKIN 121
           RL+S +GDGAWCP   V P + +E+LQ+DL  LH + LVGTQGRHAGG G EF+  Y++ 
Sbjct: 63  RLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLR 121

Query: 122 YSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVE 181
           YSRDG RW+ W++R G++V+ GN +P  + LKDL PP+VAR VRF P  D  M+VC+RVE
Sbjct: 122 YSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVE 181

Query: 182 LYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGVSGLD 240
           LYGC+W DGL+SY AP GQ   L     +YLNDS YDG  VG     GLGQL DGV GLD
Sbjct: 182 LYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLD 239

Query: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300
           DF ++ E  VWPGYDYVGW N S ++GY+E+ FEFDR+R F  M+VHCNNM   G ++  
Sbjct: 240 DFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPG 299

Query: 301 EVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMF 359
            V+C FR   A  WE   +   L  +  +P AR V+VPL  R+A  ++C++ FA  W++F
Sbjct: 300 GVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLF 359

Query: 360 SEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDSNTRI 400
           SEI+F SD  + N+S AL    P +P               + P    P+ K + S T I
Sbjct: 360 SEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAI 418

Query: 401 LIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNN--- 457
           LIGCLVAII +LL II ++LWR  W+++L KA RR+L++E+TV LS+P D+ + NN    
Sbjct: 419 LIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGP 478

Query: 458 -----------RSSSPSEQGSNSTYDRIFPLRPDYQ--------EPSRLIRKLPEFAPGE 498
                      R + P           +    P Y+         P       P +A   
Sbjct: 479 REPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPT 538

Query: 499 EESGCSG-VVKPVQPSGP-------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSG 550
                SG  ++P +P  P         VPHYAEADIV LQGVTGGNTY+VPA+    +  
Sbjct: 539 NTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGD 598

Query: 551 KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKML 610
               V+ FPR  L FKEKLGEGQFGEVHLCEV+  +     DF L+V    P+LVAVK+L
Sbjct: 599 GPPRVD-FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKIL 657

Query: 611 RADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE 670
           R DA KNARNDFLKE+KIMSRLKDPNII LL VC+ DDPLCMIT+YMENGDLNQFLS H+
Sbjct: 658 RPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 717

Query: 671 ---------PPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKN 721
                    P +  ++   T+SY  L  +A QIASGM+YL++LNFVHRDLATRNCLVG+N
Sbjct: 718 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 777

Query: 722 YTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETF 781
           +TIKIADFGMSRNLY+GDYYR+QGRAVLPIRWM+WE IL+GKFTTASDVWAFGVTLWE  
Sbjct: 778 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 837

Query: 782 TFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPS 841
             C+ QP+ QL+DEQVIEN GEFFRDQGRQ YL +P  CP  +Y+LML CW R+++ RP 
Sbjct: 838 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 897

Query: 842 FQEIHLLLLQ 851
           F ++H  L +
Sbjct: 898 FSQLHRFLAE 907


>gi|83977452 discoidin domain receptor family, member 1 isoform c
           [Homo sapiens]
          Length = 919

 Score =  905 bits (2339), Expect = 0.0
 Identities = 480/916 (52%), Positives = 598/916 (65%), Gaps = 74/916 (8%)

Query: 5   PRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYG 61
           P  L  L LLL + S     K   +PA CRY LGM    IPD DI+ASS WS+STAA++ 
Sbjct: 3   PEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHS 62

Query: 62  RLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKIN 121
           RL+S +GDGAWCP   V P + +E+LQ+DL  LH + LVGTQGRHAGG G EF+  Y++ 
Sbjct: 63  RLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLR 121

Query: 122 YSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVE 181
           YSRDG RW+ W++R G++V+ GN +P  + LKDL PP+VAR VRF P  D  M+VC+RVE
Sbjct: 122 YSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVE 181

Query: 182 LYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGVSGLD 240
           LYGC+W DGL+SY AP GQ   L     +YLNDS YDG  VG     GLGQL DGV GLD
Sbjct: 182 LYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLD 239

Query: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300
           DF ++ E  VWPGYDYVGW N S ++GY+E+ FEFDR+R F  M+VHCNNM   G ++  
Sbjct: 240 DFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPG 299

Query: 301 EVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMF 359
            V+C FR   A  WE   +   L  +  +P AR V+VPL  R+A  ++C++ FA  W++F
Sbjct: 300 GVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLF 359

Query: 360 SEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDSNTRI 400
           SEI+F SD  + N+S AL    P +P               + P    P+ K + S T I
Sbjct: 360 SEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAI 418

Query: 401 LIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNN--- 457
           LIGCLVAII +LL II ++LWR  W+++L KA RR+L++E+TV LS+P D+ + NN    
Sbjct: 419 LIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGP 478

Query: 458 -----------RSSSPSEQGSNSTYDRIFPLRPDYQ--------EPSRLIRKLPEFAPGE 498
                      R + P           +    P Y+         P       P +A   
Sbjct: 479 REPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPT 538

Query: 499 EESGCSG-VVKPVQPSGP-------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSG 550
                SG  ++P +P  P         VPHYAEADIV LQGVTGGNTY+VPA+    +  
Sbjct: 539 NTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGD 598

Query: 551 KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKML 610
               V+ FPR  L FKEKLGEGQFGEVHLCEV+  +     DF L+V    P+LVAVK+L
Sbjct: 599 GPPRVD-FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKIL 657

Query: 611 RADANKNA------RNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664
           R DA KNA      RNDFLKE+KIMSRLKDPNII LL VC+ DDPLCMIT+YMENGDLNQ
Sbjct: 658 RPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ 717

Query: 665 FLSRHE---------PPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRN 715
           FLS H+         P +  ++   T+SY  L  +A QIASGM+YL++LNFVHRDLATRN
Sbjct: 718 FLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRN 777

Query: 716 CLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGV 775
           CLVG+N+TIKIADFGMSRNLY+GDYYR+QGRAVLPIRWM+WE IL+GKFTTASDVWAFGV
Sbjct: 778 CLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGV 837

Query: 776 TLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRD 835
           TLWE    C+ QP+ QL+DEQVIEN GEFFRDQGRQ YL +P  CP  +Y+LML CW R+
Sbjct: 838 TLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRE 897

Query: 836 TKNRPSFQEIHLLLLQ 851
           ++ RP F ++H  L +
Sbjct: 898 SEQRPPFSQLHRFLAE 913


>gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isoform
           c precursor [Homo sapiens]
          Length = 822

 Score =  253 bits (647), Expect = 4e-67
 Identities = 148/341 (43%), Positives = 204/341 (59%), Gaps = 27/341 (7%)

Query: 512 PSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGE 571
           PS  EG P   +A I+ +  +          +T   L   D  V+   R  +  K +LGE
Sbjct: 491 PSSSEGGP---DAVIIGMTKIPVIENPQYFGITNSQLK-PDTFVQHIKRHNIVLKRELGE 546

Query: 572 GQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSR 631
           G FG+V L E   +   +DK           +LVAVK L+ DA+ NAR DF +E ++++ 
Sbjct: 547 GAFGKVFLAECYNLCPEQDK-----------ILVAVKTLK-DASDNARKDFHREAELLTN 594

Query: 632 LKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPN---SSSSDVRTVSYTNLK 688
           L+  +I+    VC+  DPL M+ EYM++GDLN+FL  H P     +  +    ++ + + 
Sbjct: 595 LQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQML 654

Query: 689 FMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAV 748
            +A QIA+GM YL+S +FVHRDLATRNCLVG+N  +KI DFGMSR++YS DYYR+ G  +
Sbjct: 655 HIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTM 714

Query: 749 LPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQ 808
           LPIRWM  ESI+  KFTT SDVW+ GV LWE FT+  +QP+ QLS+ +VIE        Q
Sbjct: 715 LPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY-GKQPWYQLSNNEVIECI-----TQ 768

Query: 809 GRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849
           GR   L +P  CP  VY+LML CW+R+   R + + IH LL
Sbjct: 769 GR--VLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLL 807


>gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isoform
           a precursor [Homo sapiens]
          Length = 838

 Score =  253 bits (647), Expect = 4e-67
 Identities = 148/341 (43%), Positives = 204/341 (59%), Gaps = 27/341 (7%)

Query: 512 PSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGE 571
           PS  EG P   +A I+ +  +          +T   L   D  V+   R  +  K +LGE
Sbjct: 507 PSSSEGGP---DAVIIGMTKIPVIENPQYFGITNSQLK-PDTFVQHIKRHNIVLKRELGE 562

Query: 572 GQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSR 631
           G FG+V L E   +   +DK           +LVAVK L+ DA+ NAR DF +E ++++ 
Sbjct: 563 GAFGKVFLAECYNLCPEQDK-----------ILVAVKTLK-DASDNARKDFHREAELLTN 610

Query: 632 LKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPN---SSSSDVRTVSYTNLK 688
           L+  +I+    VC+  DPL M+ EYM++GDLN+FL  H P     +  +    ++ + + 
Sbjct: 611 LQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQML 670

Query: 689 FMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAV 748
            +A QIA+GM YL+S +FVHRDLATRNCLVG+N  +KI DFGMSR++YS DYYR+ G  +
Sbjct: 671 HIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTM 730

Query: 749 LPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQ 808
           LPIRWM  ESI+  KFTT SDVW+ GV LWE FT+  +QP+ QLS+ +VIE        Q
Sbjct: 731 LPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY-GKQPWYQLSNNEVIECI-----TQ 784

Query: 809 GRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849
           GR   L +P  CP  VY+LML CW+R+   R + + IH LL
Sbjct: 785 GR--VLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLL 823


>gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isoform
           b precursor [Homo sapiens]
          Length = 825

 Score =  248 bits (633), Expect = 2e-65
 Identities = 139/304 (45%), Positives = 189/304 (62%), Gaps = 26/304 (8%)

Query: 552 DVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLR 611
           D  V+   R+ +  K +LGEG FG+V L E   +   KDK           +LVAVK L+
Sbjct: 527 DTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDK-----------MLVAVKALK 575

Query: 612 ADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEP 671
            D    AR DF +E ++++ L+  +I+    VC   DPL M+ EYM++GDLN+FL  H P
Sbjct: 576 -DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGP 634

Query: 672 PNSSSSDVRT------VSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIK 725
                 D +       +  + +  +A+QIASGM YL+S +FVHRDLATRNCLVG N  +K
Sbjct: 635 DAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVK 694

Query: 726 IADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQ 785
           I DFGMSR++YS DYYR+ G  +LPIRWM  ESI+  KFTT SDVW+FGV LWE FT+  
Sbjct: 695 IGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY-G 753

Query: 786 EQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEI 845
           +QP+ QLS+ +VIE        QGR   L +P +CP  VY +ML CW+R+ + R + +EI
Sbjct: 754 KQPWFQLSNTEVIECI-----TQGR--VLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 806

Query: 846 HLLL 849
           + +L
Sbjct: 807 YKIL 810


>gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isoform
           1 [Homo sapiens]
          Length = 790

 Score =  244 bits (622), Expect = 3e-64
 Identities = 135/303 (44%), Positives = 188/303 (62%), Gaps = 25/303 (8%)

Query: 552 DVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLR 611
           D  V    R+ +  K +LGEG FG+V L E   +   +DK           +LVAVK L+
Sbjct: 493 DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDK-----------MLVAVKALK 541

Query: 612 ADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEP 671
            +A+++AR DF +E ++++ L+  +I+    VC    PL M+ EYM +GDLN+FL  H P
Sbjct: 542 -EASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP 600

Query: 672 PN---SSSSDVRT--VSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKI 726
                +   DV    +    L  +A+Q+A+GM YL+ L+FVHRDLATRNCLVG+   +KI
Sbjct: 601 DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKI 660

Query: 727 ADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQE 786
            DFGMSR++YS DYYR+ GR +LPIRWM  ESIL  KFTT SDVW+FGV LWE FT+  +
Sbjct: 661 GDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTY-GK 719

Query: 787 QPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           QP+ QLS+ + I+        QGR+  L +P  CP  VY +M  CW+R+ + R S +++H
Sbjct: 720 QPWYQLSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKDVH 772

Query: 847 LLL 849
             L
Sbjct: 773 ARL 775


>gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isoform 2
           [Homo sapiens]
          Length = 796

 Score =  244 bits (622), Expect = 3e-64
 Identities = 135/303 (44%), Positives = 188/303 (62%), Gaps = 25/303 (8%)

Query: 552 DVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLR 611
           D  V    R+ +  K +LGEG FG+V L E   +   +DK           +LVAVK L+
Sbjct: 499 DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDK-----------MLVAVKALK 547

Query: 612 ADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEP 671
            +A+++AR DF +E ++++ L+  +I+    VC    PL M+ EYM +GDLN+FL  H P
Sbjct: 548 -EASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP 606

Query: 672 PN---SSSSDVRT--VSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKI 726
                +   DV    +    L  +A+Q+A+GM YL+ L+FVHRDLATRNCLVG+   +KI
Sbjct: 607 DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKI 666

Query: 727 ADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQE 786
            DFGMSR++YS DYYR+ GR +LPIRWM  ESIL  KFTT SDVW+FGV LWE FT+  +
Sbjct: 667 GDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTY-GK 725

Query: 787 QPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           QP+ QLS+ + I+        QGR+  L +P  CP  VY +M  CW+R+ + R S +++H
Sbjct: 726 QPWYQLSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKDVH 778

Query: 847 LLL 849
             L
Sbjct: 779 ARL 781


>gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isoform
           3 [Homo sapiens]
          Length = 760

 Score =  244 bits (622), Expect = 3e-64
 Identities = 135/303 (44%), Positives = 188/303 (62%), Gaps = 25/303 (8%)

Query: 552 DVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLR 611
           D  V    R+ +  K +LGEG FG+V L E   +   +DK           +LVAVK L+
Sbjct: 463 DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDK-----------MLVAVKALK 511

Query: 612 ADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEP 671
            +A+++AR DF +E ++++ L+  +I+    VC    PL M+ EYM +GDLN+FL  H P
Sbjct: 512 -EASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP 570

Query: 672 PN---SSSSDVRT--VSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKI 726
                +   DV    +    L  +A+Q+A+GM YL+ L+FVHRDLATRNCLVG+   +KI
Sbjct: 571 DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKI 630

Query: 727 ADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQE 786
            DFGMSR++YS DYYR+ GR +LPIRWM  ESIL  KFTT SDVW+FGV LWE FT+  +
Sbjct: 631 GDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTY-GK 689

Query: 787 QPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           QP+ QLS+ + I+        QGR+  L +P  CP  VY +M  CW+R+ + R S +++H
Sbjct: 690 QPWYQLSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKDVH 742

Query: 847 LLL 849
             L
Sbjct: 743 ARL 745


>gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isoform
           a precursor [Homo sapiens]
          Length = 839

 Score =  238 bits (608), Expect = 1e-62
 Identities = 139/318 (43%), Positives = 189/318 (59%), Gaps = 40/318 (12%)

Query: 552 DVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLR 611
           D  V+   R+ +  K +LGEG FG+V L E   +   KDK           +LVAVK L+
Sbjct: 527 DTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDK-----------MLVAVKALK 575

Query: 612 ADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEP 671
            D    AR DF +E ++++ L+  +I+    VC   DPL M+ EYM++GDLN+FL  H P
Sbjct: 576 -DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGP 634

Query: 672 PNSSSSDVRT------VSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIK 725
                 D +       +  + +  +A+QIASGM YL+S +FVHRDLATRNCLVG N  +K
Sbjct: 635 DAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVK 694

Query: 726 IADFGMSRNLYSGDYYR--------------IQGRAVLPIRWMSWESILLGKFTTASDVW 771
           I DFGMSR++YS DYYR              + G  +LPIRWM  ESI+  KFTT SDVW
Sbjct: 695 IGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVW 754

Query: 772 AFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSC 831
           +FGV LWE FT+  +QP+ QLS+ +VIE        QGR   L +P +CP  VY +ML C
Sbjct: 755 SFGVILWEIFTY-GKQPWFQLSNTEVIECI-----TQGR--VLERPRVCPKEVYDVMLGC 806

Query: 832 WRRDTKNRPSFQEIHLLL 849
           W+R+ + R + +EI+ +L
Sbjct: 807 WQREPQQRLNIKEIYKIL 824


>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
          Length = 869

 Score =  226 bits (576), Expect = 7e-59
 Identities = 130/319 (40%), Positives = 178/319 (55%), Gaps = 33/319 (10%)

Query: 545 MDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVL 604
           M LL    +   E+PR  + +   +GEG FG V      G+  ++              +
Sbjct: 557 MPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPF-----------TM 605

Query: 605 VAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664
           VAVKML+ +A+ + + DF +E  +M+   +PNI+ LL VC    P+C++ EYM  GDLN+
Sbjct: 606 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 665

Query: 665 FL---SRHEPPNSSSSDVRT-----------VSYTNLKFMATQIASGMKYLSSLNFVHRD 710
           FL   S H   + S SD+             +S      +A Q+A+GM YLS   FVHRD
Sbjct: 666 FLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD 725

Query: 711 LATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDV 770
           LATRNCLVG+N  +KIADFG+SRN+YS DYY+      +PIRWM  ESI   ++TT SDV
Sbjct: 726 LATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDV 785

Query: 771 WAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLS 830
           WA+GV LWE F++   QPY  ++ E+VI     + RD      L  P  CP  +Y LM  
Sbjct: 786 WAYGVVLWEIFSY-GLQPYYGMAHEEVI----YYVRD---GNILSCPENCPVELYNLMRL 837

Query: 831 CWRRDTKNRPSFQEIHLLL 849
           CW +   +RPSF  IH +L
Sbjct: 838 CWSKLPADRPSFTSIHRIL 856


>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
            sapiens]
          Length = 1367

 Score =  212 bits (539), Expect = 1e-54
 Identities = 126/314 (40%), Positives = 174/314 (55%), Gaps = 22/314 (7%)

Query: 535  GNTYSVPAVTMDLLSGKDVAVE---EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDK 591
            GN     +V  +  S  DV V    E  R+ +T   +LG+G FG V+    EG+ K   K
Sbjct: 968  GNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVY----EGVAKGVVK 1023

Query: 592  DFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLC 651
            D            VA+K +   A+   R +FL E  +M      +++ LL V     P  
Sbjct: 1024 D-------EPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTL 1076

Query: 652  MITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDL 711
            +I E M  GDL  +L    P   ++  +   S + +  MA +IA GM YL++  FVHRDL
Sbjct: 1077 VIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDL 1136

Query: 712  ATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVW 771
            A RNC+V +++T+KI DFGM+R++Y  DYYR  G+ +LP+RWMS ES+  G FTT SDVW
Sbjct: 1137 AARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVW 1196

Query: 772  AFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSC 831
            +FGV LWE  T   EQPY  LS+EQV+     F  + G    L +P  CPD +++LM  C
Sbjct: 1197 SFGVVLWEIATLA-EQPYQGLSNEQVL----RFVMEGG---LLDKPDNCPDMLFELMRMC 1248

Query: 832  WRRDTKNRPSFQEI 845
            W+ + K RPSF EI
Sbjct: 1249 WQYNPKMRPSFLEI 1262


>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
           isoform 1 [Homo sapiens]
          Length = 937

 Score =  211 bits (536), Expect = 3e-54
 Identities = 120/301 (39%), Positives = 173/301 (57%), Gaps = 27/301 (8%)

Query: 556 EEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADAN 615
           +E P   + F E+LGE  FG+++    +G       D A         LVA+K L+   N
Sbjct: 466 KELPLSAVRFMEELGECAFGKIY----KGHLYLPGMDHAQ--------LVAIKTLKDYNN 513

Query: 616 KNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFL---SRHEPP 672
                +F +E  +M+ L  PNI+ LL     + P+CM+ EY+  GDL++FL   S H   
Sbjct: 514 PQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDV 573

Query: 673 NSSSSDVRTVS----YTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIAD 728
             SS +  TV     + +   +A QIA+GM+YLSS  FVH+DLA RN L+G+   +KI+D
Sbjct: 574 GCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISD 633

Query: 729 FGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQP 788
            G+SR +YS DYYR+Q +++LPIRWM  E+I+ GKF++ SD+W+FGV LWE F+F   QP
Sbjct: 634 LGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSF-GLQP 692

Query: 789 YSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLL 848
           Y   S+++VIE          ++  LP    CP  +Y LM  CW      RP F++IH+ 
Sbjct: 693 YYGFSNQEVIEMV-------RKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVR 745

Query: 849 L 849
           L
Sbjct: 746 L 746


>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
           precursor [Homo sapiens]
          Length = 943

 Score =  204 bits (520), Expect = 2e-52
 Identities = 119/310 (38%), Positives = 172/310 (55%), Gaps = 25/310 (8%)

Query: 551 KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKML 610
           K   ++E     + F E+LGE +FG+V+   + G                Q   VA+K L
Sbjct: 461 KQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFG-----------PAPGEQTQAVAIKTL 509

Query: 611 RADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE 670
           +  A    R +F  E  + +RL+ PN++ LL V   D PL MI  Y  +GDL++FL    
Sbjct: 510 KDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRS 569

Query: 671 PPNS--SSSDVRTVSYT----NLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTI 724
           P +   S+ D RTV       +   +  QIA+GM+YLSS + VH+DLATRN LV     +
Sbjct: 570 PHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNV 629

Query: 725 KIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC 784
           KI+D G+ R +Y+ DYY++ G ++LPIRWM+ E+I+ GKF+  SD+W++GV LWE F++ 
Sbjct: 630 KISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY- 688

Query: 785 QEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQE 844
             QPY   S++ V+E        + RQ  LP P  CP  VY LM+ CW      RP F++
Sbjct: 689 GLQPYCGYSNQDVVEMI------RNRQV-LPCPDDCPAWVYALMIECWNEFPSRRPRFKD 741

Query: 845 IHLLLLQQGD 854
           IH  L   G+
Sbjct: 742 IHSRLRAWGN 751


>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
          Length = 1370

 Score =  202 bits (515), Expect = 8e-52
 Identities = 128/339 (37%), Positives = 181/339 (53%), Gaps = 31/339 (9%)

Query: 511  QPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLG 570
            QP GP G P YA +   N + ++  + +       D          E  R+ +T   +LG
Sbjct: 971  QPDGPLG-PLYASS---NPEYLSASDVFPCSVYVPDEW--------EVSREKITLLRELG 1018

Query: 571  EGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMS 630
            +G FG V+    EG      +D    +       VAVK +   A+   R +FL E  +M 
Sbjct: 1019 QGSFGMVY----EG----NARDI---IKGEAETRVAVKTVNESASLRERIEFLNEASVMK 1067

Query: 631  RLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFM 690
                 +++ LL V     P  ++ E M +GDL  +L    P   ++      +   +  M
Sbjct: 1068 GFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQM 1127

Query: 691  ATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLP 750
            A +IA GM YL++  FVHRDLA RNC+V  ++T+KI DFGM+R++Y  DYYR  G+ +LP
Sbjct: 1128 AAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLP 1187

Query: 751  IRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGR 810
            +RWM+ ES+  G FTT+SD+W+FGV LWE  T   EQPY  LS+EQV+    +F  D G 
Sbjct: 1188 VRWMAPESLKDGVFTTSSDMWSFGVVLWE-ITSLAEQPYQGLSNEQVL----KFVMDGG- 1241

Query: 811  QTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849
              YL QP  CP+ V  LM  CW+ + K RP+F EI  LL
Sbjct: 1242 --YLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1278


>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
          Length = 1382

 Score =  202 bits (515), Expect = 8e-52
 Identities = 128/339 (37%), Positives = 181/339 (53%), Gaps = 31/339 (9%)

Query: 511  QPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLG 570
            QP GP G P YA +   N + ++  + +       D          E  R+ +T   +LG
Sbjct: 983  QPDGPLG-PLYASS---NPEYLSASDVFPCSVYVPDEW--------EVSREKITLLRELG 1030

Query: 571  EGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMS 630
            +G FG V+    EG      +D    +       VAVK +   A+   R +FL E  +M 
Sbjct: 1031 QGSFGMVY----EG----NARDI---IKGEAETRVAVKTVNESASLRERIEFLNEASVMK 1079

Query: 631  RLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFM 690
                 +++ LL V     P  ++ E M +GDL  +L    P   ++      +   +  M
Sbjct: 1080 GFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQM 1139

Query: 691  ATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLP 750
            A +IA GM YL++  FVHRDLA RNC+V  ++T+KI DFGM+R++Y  DYYR  G+ +LP
Sbjct: 1140 AAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLP 1199

Query: 751  IRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGR 810
            +RWM+ ES+  G FTT+SD+W+FGV LWE  T   EQPY  LS+EQV+    +F  D G 
Sbjct: 1200 VRWMAPESLKDGVFTTSSDMWSFGVVLWE-ITSLAEQPYQGLSNEQVL----KFVMDGG- 1253

Query: 811  QTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849
              YL QP  CP+ V  LM  CW+ + K RP+F EI  LL
Sbjct: 1254 --YLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1290


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
           [Homo sapiens]
          Length = 1130

 Score =  201 bits (512), Expect = 2e-51
 Identities = 119/290 (41%), Positives = 165/290 (56%), Gaps = 35/290 (12%)

Query: 557 EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANK 616
           E  R  +T K KLG GQ+GEV+    EG+ K               + VAVK L+ D  +
Sbjct: 236 EMERTDITMKHKLGGGQYGEVY----EGVWK------------KYSLTVAVKTLKEDTME 279

Query: 617 NARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSS 676
               +FLKE  +M  +K PN++ LL VC  + P  +ITE+M  G+L  +L          
Sbjct: 280 V--EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRE-------- 329

Query: 677 SDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLY 736
            + + V+   L +MATQI+S M+YL   NF+HRDLA RNCLVG+N+ +K+ADFG+SR L 
Sbjct: 330 CNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LM 388

Query: 737 SGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ 796
           +GD Y     A  PI+W + ES+   KF+  SDVWAFGV LWE  T+    PY  +   Q
Sbjct: 389 TGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQ 447

Query: 797 VIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           V E   + +R       + +P  CP+ VY+LM +CW+ +  +RPSF EIH
Sbjct: 448 VYELLEKDYR-------MERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 490


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
           [Homo sapiens]
          Length = 1149

 Score =  201 bits (512), Expect = 2e-51
 Identities = 119/290 (41%), Positives = 165/290 (56%), Gaps = 35/290 (12%)

Query: 557 EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANK 616
           E  R  +T K KLG GQ+GEV+    EG+ K               + VAVK L+ D  +
Sbjct: 255 EMERTDITMKHKLGGGQYGEVY----EGVWK------------KYSLTVAVKTLKEDTME 298

Query: 617 NARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSS 676
               +FLKE  +M  +K PN++ LL VC  + P  +ITE+M  G+L  +L          
Sbjct: 299 V--EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRE-------- 348

Query: 677 SDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLY 736
            + + V+   L +MATQI+S M+YL   NF+HRDLA RNCLVG+N+ +K+ADFG+SR L 
Sbjct: 349 CNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LM 407

Query: 737 SGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ 796
           +GD Y     A  PI+W + ES+   KF+  SDVWAFGV LWE  T+    PY  +   Q
Sbjct: 408 TGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQ 466

Query: 797 VIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           V E   + +R       + +P  CP+ VY+LM +CW+ +  +RPSF EIH
Sbjct: 467 VYELLEKDYR-------MERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 509


>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
           sapiens]
          Length = 983

 Score =  198 bits (503), Expect = 2e-50
 Identities = 118/302 (39%), Positives = 168/302 (55%), Gaps = 37/302 (12%)

Query: 554 AVEEFPRKL----LTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKM 609
           AV EF ++L    ++  + +G G+FGEV      G  K   K         + + VA+K 
Sbjct: 608 AVHEFAKELDATNISIDKVVGAGEFGEV----CSGRLKLPSK---------KEISVAIKT 654

Query: 610 LRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRH 669
           L+    +  R DFL E  IM +   PNII L  V     P+ ++TEYMENG L+ FL +H
Sbjct: 655 LKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKH 714

Query: 670 EPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADF 729
           +            +   L  M   IASGMKYLS + +VHRDLA RN L+  N   K++DF
Sbjct: 715 D---------AQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDF 765

Query: 730 GMSRNLYSGD--YYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQ 787
           G+SR L       Y  +G   +PIRW S E+I   KFT+ASDVW++G+ LWE  ++  E+
Sbjct: 766 GLSRVLEDDPEAAYTTRG-GKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSY-GER 823

Query: 788 PYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHL 847
           PY ++S++ VI+   E +R       LP P  CP ++Y+LML CW++D  NRP F++I  
Sbjct: 824 PYWEMSNQDVIKAVDEGYR-------LPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876

Query: 848 LL 849
           +L
Sbjct: 877 IL 878


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score =  196 bits (498), Expect = 8e-50
 Identities = 115/290 (39%), Positives = 158/290 (54%), Gaps = 35/290 (12%)

Query: 557 EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANK 616
           E  R  +T K KLG GQ+GEV++                 V     + VAVK L+ D  +
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 310

Query: 617 NARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSS 676
               +FLKE  +M  +K PN++ LL VC  + P  ++TEYM  G+L  +L          
Sbjct: 311 V--EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE-------- 360

Query: 677 SDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLY 736
            +   V+   L +MATQI+S M+YL   NF+HRDLA RNCLVG+N+ +K+ADFG+SR L 
Sbjct: 361 CNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LM 419

Query: 737 SGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ 796
           +GD Y     A  PI+W + ES+    F+  SDVWAFGV LWE  T+    PY  +   Q
Sbjct: 420 TGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQ 478

Query: 797 VIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           V +   + +R       + QP  CP  VY+LM +CW+    +RPSF E H
Sbjct: 479 VYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPSFAETH 521


>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
          Length = 1182

 Score =  196 bits (498), Expect = 8e-50
 Identities = 115/290 (39%), Positives = 158/290 (54%), Gaps = 35/290 (12%)

Query: 557 EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANK 616
           E  R  +T K KLG GQ+GEV++                 V     + VAVK L+ D  +
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 325

Query: 617 NARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSS 676
               +FLKE  +M  +K PN++ LL VC  + P  ++TEYM  G+L  +L          
Sbjct: 326 V--EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE-------- 375

Query: 677 SDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLY 736
            +   V+   L +MATQI+S M+YL   NF+HRDLA RNCLVG+N+ +K+ADFG+SR L 
Sbjct: 376 CNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LM 434

Query: 737 SGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ 796
           +GD Y     A  PI+W + ES+    F+  SDVWAFGV LWE  T+    PY  +   Q
Sbjct: 435 TGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQ 493

Query: 797 VIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           V +   + +R       + QP  CP  VY+LM +CW+    +RPSF E H
Sbjct: 494 VYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPSFAETH 536


>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
          Length = 542

 Score =  196 bits (498), Expect = 8e-50
 Identities = 115/290 (39%), Positives = 158/290 (54%), Gaps = 35/290 (12%)

Query: 557 EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANK 616
           E  R  +T K KLG GQ+GEV++                 V     + VAVK L+ D  +
Sbjct: 261 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 304

Query: 617 NARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSS 676
               +FLKE  +M  +K PN++ LL VC  + P  ++TEYM  G+L  +L          
Sbjct: 305 V--EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE-------- 354

Query: 677 SDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLY 736
            +   V+   L +MATQI+S M+YL   NF+HRDLA RNCLVG+N+ +K+ADFG+SR L 
Sbjct: 355 CNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LM 413

Query: 737 SGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ 796
           +GD Y     A  PI+W + ES+    F+  SDVWAFGV LWE  T+    PY  +   Q
Sbjct: 414 TGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQ 472

Query: 797 VIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           V +   + +R       + QP  CP  VY+LM +CW+    +RPSF E H
Sbjct: 473 VYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPSFAETH 515


>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
          Length = 1064

 Score =  196 bits (498), Expect = 8e-50
 Identities = 115/290 (39%), Positives = 158/290 (54%), Gaps = 35/290 (12%)

Query: 557 EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANK 616
           E  R  +T K KLG GQ+GEV++                 V     + VAVK L+ D  +
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 310

Query: 617 NARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSS 676
               +FLKE  +M  +K PN++ LL VC  + P  ++TEYM  G+L  +L          
Sbjct: 311 V--EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE-------- 360

Query: 677 SDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLY 736
            +   V+   L +MATQI+S M+YL   NF+HRDLA RNCLVG+N+ +K+ADFG+SR L 
Sbjct: 361 CNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LM 419

Query: 737 SGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ 796
           +GD Y     A  PI+W + ES+    F+  SDVWAFGV LWE  T+    PY  +   Q
Sbjct: 420 TGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQ 478

Query: 797 VIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           V +   + +R       + QP  CP  VY+LM +CW+    +RPSF E H
Sbjct: 479 VYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPSFAETH 521


>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
          Length = 1146

 Score =  196 bits (498), Expect = 8e-50
 Identities = 115/290 (39%), Positives = 158/290 (54%), Gaps = 35/290 (12%)

Query: 557 EFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANK 616
           E  R  +T K KLG GQ+GEV++                 V     + VAVK L+ D  +
Sbjct: 246 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 289

Query: 617 NARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSS 676
               +FLKE  +M  +K PN++ LL VC  + P  ++TEYM  G+L  +L          
Sbjct: 290 V--EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE-------- 339

Query: 677 SDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLY 736
            +   V+   L +MATQI+S M+YL   NF+HRDLA RNCLVG+N+ +K+ADFG+SR L 
Sbjct: 340 CNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LM 398

Query: 737 SGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ 796
           +GD Y     A  PI+W + ES+    F+  SDVWAFGV LWE  T+    PY  +   Q
Sbjct: 399 TGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQ 457

Query: 797 VIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIH 846
           V +   + +R       + QP  CP  VY+LM +CW+    +RPSF E H
Sbjct: 458 VYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPSFAETH 500


>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [Homo
            sapiens]
          Length = 1070

 Score =  194 bits (494), Expect = 2e-49
 Identities = 127/361 (35%), Positives = 193/361 (53%), Gaps = 35/361 (9%)

Query: 485  SRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVT 544
            ++ ++K PE    E E    G ++  QPS          A+I     +T  +  S PA T
Sbjct: 732  AKRLQKQPEGEEPEMECLNGGPLQNGQPS----------AEIQEEVALT--SLGSGPAAT 779

Query: 545  MDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVL 604
                S  D     FPR  L     LG+ +FGEV L + +G+E+                L
Sbjct: 780  NKRHSTSDKM--HFPRSSLQPITTLGKSEFGEVFLAKAQGLEE-----------GVAETL 826

Query: 605  VAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664
            V VK L++  ++  + DF +E+++  +L   N++ LL +C   +P  M+ EY++ GDL Q
Sbjct: 827  VLVKSLQSK-DEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQ 885

Query: 665  FLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTI 724
            FL R           + +S      + TQ+A GM++LS+  FVH+DLA RNCLV     +
Sbjct: 886  FL-RISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQV 944

Query: 725  KIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC 784
            K++  G+S+++Y+ +YY  + +A +P+RWMS E+IL G F+T SDVWAFGV +WE FT  
Sbjct: 945  KVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTH- 1002

Query: 785  QEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQE 844
             E P+   +D++V+ +       Q  +  LPQP  CP  +Y+LM  CW    K+RPSF E
Sbjct: 1003 GEMPHGGQADDEVLADL------QAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSE 1056

Query: 845  I 845
            I
Sbjct: 1057 I 1057


>gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [Homo
            sapiens]
          Length = 1014

 Score =  194 bits (494), Expect = 2e-49
 Identities = 127/361 (35%), Positives = 193/361 (53%), Gaps = 35/361 (9%)

Query: 485  SRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVT 544
            ++ ++K PE    E E    G ++  QPS          A+I     +T  +  S PA T
Sbjct: 676  AKRLQKQPEGEEPEMECLNGGPLQNGQPS----------AEIQEEVALT--SLGSGPAAT 723

Query: 545  MDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVL 604
                S  D     FPR  L     LG+ +FGEV L + +G+E+                L
Sbjct: 724  NKRHSTSDKM--HFPRSSLQPITTLGKSEFGEVFLAKAQGLEE-----------GVAETL 770

Query: 605  VAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664
            V VK L++  ++  + DF +E+++  +L   N++ LL +C   +P  M+ EY++ GDL Q
Sbjct: 771  VLVKSLQSK-DEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQ 829

Query: 665  FLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTI 724
            FL R           + +S      + TQ+A GM++LS+  FVH+DLA RNCLV     +
Sbjct: 830  FL-RISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQV 888

Query: 725  KIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC 784
            K++  G+S+++Y+ +YY  + +A +P+RWMS E+IL G F+T SDVWAFGV +WE FT  
Sbjct: 889  KVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTH- 946

Query: 785  QEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQE 844
             E P+   +D++V+ +       Q  +  LPQP  CP  +Y+LM  CW    K+RPSF E
Sbjct: 947  GEMPHGGQADDEVLADL------QAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSE 1000

Query: 845  I 845
            I
Sbjct: 1001 I 1001


>gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor
           [Homo sapiens]
          Length = 940

 Score =  194 bits (494), Expect = 2e-49
 Identities = 127/361 (35%), Positives = 193/361 (53%), Gaps = 35/361 (9%)

Query: 485 SRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVT 544
           ++ ++K PE    E E    G ++  QPS          A+I     +T  +  S PA T
Sbjct: 602 AKRLQKQPEGEEPEMECLNGGPLQNGQPS----------AEIQEEVALT--SLGSGPAAT 649

Query: 545 MDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVL 604
               S  D     FPR  L     LG+ +FGEV L + +G+E+                L
Sbjct: 650 NKRHSTSDKM--HFPRSSLQPITTLGKSEFGEVFLAKAQGLEE-----------GVAETL 696

Query: 605 VAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664
           V VK L++  ++  + DF +E+++  +L   N++ LL +C   +P  M+ EY++ GDL Q
Sbjct: 697 VLVKSLQSK-DEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQ 755

Query: 665 FLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTI 724
           FL R           + +S      + TQ+A GM++LS+  FVH+DLA RNCLV     +
Sbjct: 756 FL-RISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQV 814

Query: 725 KIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC 784
           K++  G+S+++Y+ +YY  + +A +P+RWMS E+IL G F+T SDVWAFGV +WE FT  
Sbjct: 815 KVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTH- 872

Query: 785 QEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQE 844
            E P+   +D++V+ +       Q  +  LPQP  CP  +Y+LM  CW    K+RPSF E
Sbjct: 873 GEMPHGGQADDEVLADL------QAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSE 926

Query: 845 I 845
           I
Sbjct: 927 I 927


>gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor [Homo
            sapiens]
          Length = 1030

 Score =  194 bits (494), Expect = 2e-49
 Identities = 127/361 (35%), Positives = 193/361 (53%), Gaps = 35/361 (9%)

Query: 485  SRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVT 544
            ++ ++K PE    E E    G ++  QPS          A+I     +T  +  S PA T
Sbjct: 692  AKRLQKQPEGEEPEMECLNGGPLQNGQPS----------AEIQEEVALT--SLGSGPAAT 739

Query: 545  MDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVL 604
                S  D     FPR  L     LG+ +FGEV L + +G+E+                L
Sbjct: 740  NKRHSTSDKM--HFPRSSLQPITTLGKSEFGEVFLAKAQGLEE-----------GVAETL 786

Query: 605  VAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664
            V VK L++  ++  + DF +E+++  +L   N++ LL +C   +P  M+ EY++ GDL Q
Sbjct: 787  VLVKSLQSK-DEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQ 845

Query: 665  FLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTI 724
            FL R           + +S      + TQ+A GM++LS+  FVH+DLA RNCLV     +
Sbjct: 846  FL-RISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQV 904

Query: 725  KIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC 784
            K++  G+S+++Y+ +YY  + +A +P+RWMS E+IL G F+T SDVWAFGV +WE FT  
Sbjct: 905  KVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTH- 962

Query: 785  QEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQE 844
             E P+   +D++V+ +       Q  +  LPQP  CP  +Y+LM  CW    K+RPSF E
Sbjct: 963  GEMPHGGQADDEVLADL------QAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSE 1016

Query: 845  I 845
            I
Sbjct: 1017 I 1017


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,016,046
Number of Sequences: 37866
Number of extensions: 1587813
Number of successful extensions: 5923
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 582
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 3870
Number of HSP's gapped (non-prelim): 991
length of query: 855
length of database: 18,247,518
effective HSP length: 111
effective length of query: 744
effective length of database: 14,044,392
effective search space: 10449027648
effective search space used: 10449027648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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