Search of human proteins with 62241024

Search of human proteins with 62241024

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
[Homo sapiens]
         (448 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [...   884   0.0  
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H...   868   0.0  
gi|8922886 DDX19-like protein [Homo sapiens]                          837   0.0  
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [...   695   0.0  
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap...   555   e-158
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   244   9e-65
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   243   3e-64
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   228   8e-60
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]               190   3e-48
gi|18375623 HLA-B associated transcript 1 [Homo sapiens]              190   3e-48
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   187   2e-47
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi...   174   1e-43
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   174   2e-43
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   149   7e-36
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            143   4e-34
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            143   4e-34
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   141   1e-33
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   141   1e-33
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   139   5e-33
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   135   6e-32
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   133   3e-31
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   132   8e-31
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   129   7e-30
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         126   3e-29
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          126   3e-29
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      125   6e-29
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   124   1e-28
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   124   1e-28
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   124   1e-28
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   122   5e-28

>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
           [Homo sapiens]
          Length = 448

 Score =  884 bits (2284), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
           MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS
Sbjct: 1   MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60

Query: 61  LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLPQNLIAQSQSGTGKTAAFVLA 120
           LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLPQNLIAQSQSGTGKTAAFVLA
Sbjct: 61  LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLPQNLIAQSQSGTGKTAAFVLA 120

Query: 121 MLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE 180
           MLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE
Sbjct: 121 MLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE 180

Query: 181 QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQML 240
           QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQML
Sbjct: 181 QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQML 240

Query: 241 LFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAI 300
           LFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAI
Sbjct: 241 LFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAI 300

Query: 301 TIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTN 360
           TIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTN
Sbjct: 301 TIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTN 360

Query: 361 VCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNI 420
           VCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNI
Sbjct: 361 VCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNI 420

Query: 421 LNRIQEHFNKKIERLDTDDLDEIEKIAN 448
           LNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 421 LNRIQEHFNKKIERLDTDDLDEIEKIAN 448


>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  868 bits (2242), Expect = 0.0
 Identities = 448/479 (93%), Positives = 448/479 (93%), Gaps = 31/479 (6%)

Query: 1   MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
           MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS
Sbjct: 1   MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60

Query: 61  LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL--------------------- 99
           LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL                     
Sbjct: 61  LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 120

Query: 100 ----------PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 149
                     PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK
Sbjct: 121 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 180

Query: 150 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 209
           VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV
Sbjct: 181 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 240

Query: 210 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 269
           LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE
Sbjct: 241 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300

Query: 270 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 329
           EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV
Sbjct: 301 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 360

Query: 330 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 389
           ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN
Sbjct: 361 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 420

Query: 390 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 448
           ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 421 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 479


>gi|8922886 DDX19-like protein [Homo sapiens]
          Length = 478

 Score =  837 bits (2162), Expect = 0.0
 Identities = 430/479 (89%), Positives = 442/479 (92%), Gaps = 32/479 (6%)

Query: 1   MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
           MATDSWALAVDEQEAA +S++NL +KEEK+K DTNG ++KT+  AEKTDEEEKEDRAAQS
Sbjct: 1   MATDSWALAVDEQEAAVKSMTNLQIKEEKVKADTNG-IIKTSTTAEKTDEEEKEDRAAQS 59

Query: 61  LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL--------------------- 99
           LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL                     
Sbjct: 60  LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 119

Query: 100 ----------PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 149
                     PQNLIAQSQSGTGKTAAFVLAMLS+VEP+++YPQCLCLSPTYELALQTGK
Sbjct: 120 NALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPSDRYPQCLCLSPTYELALQTGK 179

Query: 150 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 209
           VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV
Sbjct: 180 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 239

Query: 210 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 269
           LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE
Sbjct: 240 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 299

Query: 270 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 329
           EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV
Sbjct: 300 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 359

Query: 330 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 389
           ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN
Sbjct: 360 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 419

Query: 390 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 448
           ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 420 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 478


>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
           [Homo sapiens]
          Length = 370

 Score =  695 bits (1794), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 100 PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP 159
           PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP
Sbjct: 22  PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP 81

Query: 160 ELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIAT 219
           ELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIAT
Sbjct: 82  ELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIAT 141

Query: 220 QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQY 279
           QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQY
Sbjct: 142 QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQY 201

Query: 280 YVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVE 339
           YVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVE
Sbjct: 202 YVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVE 261

Query: 340 QRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT 399
           QRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT
Sbjct: 262 QRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT 321

Query: 400 GRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 448
           GRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 322 GRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 370


>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
           sapiens]
          Length = 483

 Score =  555 bits (1430), Expect = e-158
 Identities = 274/434 (63%), Positives = 343/434 (79%), Gaps = 32/434 (7%)

Query: 44  NAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL---- 99
           N  + DEE+  D AA SLLNKLI  +LV+++++VEVLQ+DP+SPLYSVK+FEELRL    
Sbjct: 49  NINEDDEEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEEL 108

Query: 100 ---------------------------PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYP 132
                                      PQNLIAQSQSGTGKTAAFVLAMLS+V     +P
Sbjct: 109 LKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFP 168

Query: 133 QCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLD 192
           QCLCL+PTYELALQTG+V+EQMGKF  ++++ YA+RGN++ RG  I++QI+IGTPGTVLD
Sbjct: 169 QCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLD 228

Query: 193 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 252
           WC KLK ID  KI+VFVLDEADVMI TQG  D SIRIQR LP  CQMLLFSATFEDSVW 
Sbjct: 229 WCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWH 288

Query: 253 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 312
           FA++++PDPNVIKL++EE TL+ I+QYYVLC  R +K+QALCN+YG+ITI QA+IFC TR
Sbjct: 289 FAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTR 348

Query: 313 KTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS 372
           + A WL  E+ ++GHQV+LLSGE+ VEQRA++I+RFR+GKEKVL+TTNVCARGIDV+QV+
Sbjct: 349 RNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVT 408

Query: 373 VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKI 432
           +V+NFDLPV +   PD ETYLHRIGRTGRFGK+GLA NM++     +++ +IQ+HFN  I
Sbjct: 409 IVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLM-KIQDHFNSSI 467

Query: 433 ERLDTDDLDEIEKI 446
           ++L+ +D+DEIEKI
Sbjct: 468 KQLNAEDMDEIEKI 481


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  244 bits (624), Expect = 9e-65
 Identities = 141/347 (40%), Positives = 215/347 (61%), Gaps = 16/347 (4%)

Query: 102 NLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPEL 161
           ++IAQ+QSGTGKTA F +++L Q+E   K  Q L L+PT ELA Q  KVI  +G +    
Sbjct: 72  DVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGAT 131

Query: 162 KLAYAVRG-----NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVM 216
              +A  G     N++++ Q  +  IV+GTPG V D  ++ +++ PK IK+FVLDEAD M
Sbjct: 132 --CHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEM 188

Query: 217 IATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTI 276
           ++ +G +DQ   I + L  + Q++L SAT    V +  +K + DP  I +K+EE TL+ I
Sbjct: 189 LS-RGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGI 247

Query: 277 KQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEM 336
           KQ+Y+     + K   LC+LY  +TI QA+IF +TR+   WL  ++      V+ L G+M
Sbjct: 248 KQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDM 307

Query: 337 MVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRI 396
             ++R  ++  FR G  +VL+TT++ ARGIDV+QVS+VIN+DLP ++      E Y+HRI
Sbjct: 308 DQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRI 361

Query: 397 GRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 443
           GR GRFG++G+A+N V ++    IL  I+  +N  +E +  +  D I
Sbjct: 362 GRGGRFGRKGVAINFV-TEEDKRILRDIETFYNTTVEEMPMNVADLI 407


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  243 bits (620), Expect = 3e-64
 Identities = 139/345 (40%), Positives = 211/345 (61%), Gaps = 12/345 (3%)

Query: 102 NLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPEL 161
           ++IAQ+QSGTGKTA F +++L Q+E   K  Q L L+PT ELA Q  KV+  +G +    
Sbjct: 71  DVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGAS 130

Query: 162 KLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIA 218
             A     N     QK+  +   I++GTPG V D  ++ +++ PK IK+FVLDEAD M++
Sbjct: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLS 189

Query: 219 TQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQ 278
            +G +DQ   I + L  N Q++L SAT    V +  +K + DP  I +K+EE TL+ I+Q
Sbjct: 190 -RGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248

Query: 279 YYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMV 338
           +Y+     + K   LC+LY  +TI QA+IF +TR+   WL  ++      V+ + G+M  
Sbjct: 249 FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQ 308

Query: 339 EQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGR 398
           ++R  ++  FR G  +VL+TT++ ARGIDV+QVS+VIN+DLP ++      E Y+HRIGR
Sbjct: 309 KERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGR 362

Query: 399 TGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 443
            GRFG++G+A+NMV ++     L  I+  +N  IE +  +  D I
Sbjct: 363 GGRFGRKGVAINMV-TEEDKRTLRDIETFYNTSIEEMPLNVADLI 406


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  228 bits (581), Expect = 8e-60
 Identities = 130/359 (36%), Positives = 219/359 (61%), Gaps = 21/359 (5%)

Query: 92  KSFEELRLPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVI 151
           ++ +++   +++IAQSQSGTGKTA F +++L  ++   +  Q L L+PT ELA+Q  K +
Sbjct: 67  RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126

Query: 152 EQMGKFYPELKLAYAVRGN-------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKK 204
             +G  Y  ++    + G        KL+ GQ     +V GTPG V D   + + +  + 
Sbjct: 127 LALGD-YMNVQCHACIGGTNVGEDIRKLDYGQ----HVVAGTPGRVFDMIRR-RSLRTRA 180

Query: 205 IKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVI 264
           IK+ VLDEAD M+  +G ++Q   + R LP   Q++L SAT    + +   K + DP  I
Sbjct: 181 IKMLVLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRI 239

Query: 265 KLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK 324
            +KR+E TL+ IKQ++V     + KF  LC+LY  +TI QA+IFC+T++   WL  ++ +
Sbjct: 240 LVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMRE 299

Query: 325 EGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKD 384
               V+ + G+M  ++R ++++ FR G  +VL++T+V ARG+DV QVS++IN+DLP ++ 
Sbjct: 300 ANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNR- 358

Query: 385 GNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 443
                E Y+HRIGR+GR+G++G+A+N V     + IL  I+++++ +I+ +  +  D I
Sbjct: 359 -----ELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRDIEQYYSTQIDEMPMNVADLI 411


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  190 bits (482), Expect = 3e-48
 Identities = 117/348 (33%), Positives = 191/348 (54%), Gaps = 14/348 (4%)

Query: 99  LPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFY 158
           L  +++ Q++SG GKTA FVLA L Q+EP       L +  T ELA Q  K  E+  K+ 
Sbjct: 81  LGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYM 140

Query: 159 PELKLAYAVRGNKLERGQKISEQ----IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 214
           P +K+A    G  +++ +++ ++    IV+GTPG +L   ++ K ++ K IK F+LDE D
Sbjct: 141 PNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILA-LARNKSLNLKHIKHFILDECD 199

Query: 215 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TL 273
            M+     +     I RM P   Q+++FSAT    +    +K + DP  I +  E + TL
Sbjct: 200 KMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTL 259

Query: 274 DTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLS 333
             ++QYYV     +EK + L +L   +   Q +IF  + +    LA  L ++      + 
Sbjct: 260 HGLQQYYVKLKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIH 318

Query: 334 GEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYL 393
             M  E+R +  ++F++ + ++LV TN+  RG+D+E+V++  N+D+P D D      TYL
Sbjct: 319 RGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSD------TYL 372

Query: 394 HRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLD 441
           HR+ R GRFG +GLA+  V  ++   ILN +Q+ F   I  L  D++D
Sbjct: 373 HRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISEL-PDEID 419


>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  190 bits (482), Expect = 3e-48
 Identities = 117/348 (33%), Positives = 191/348 (54%), Gaps = 14/348 (4%)

Query: 99  LPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFY 158
           L  +++ Q++SG GKTA FVLA L Q+EP       L +  T ELA Q  K  E+  K+ 
Sbjct: 81  LGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYM 140

Query: 159 PELKLAYAVRGNKLERGQKISEQ----IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 214
           P +K+A    G  +++ +++ ++    IV+GTPG +L   ++ K ++ K IK F+LDE D
Sbjct: 141 PNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILA-LARNKSLNLKHIKHFILDECD 199

Query: 215 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TL 273
            M+     +     I RM P   Q+++FSAT    +    +K + DP  I +  E + TL
Sbjct: 200 KMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTL 259

Query: 274 DTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLS 333
             ++QYYV     +EK + L +L   +   Q +IF  + +    LA  L ++      + 
Sbjct: 260 HGLQQYYVKLKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIH 318

Query: 334 GEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYL 393
             M  E+R +  ++F++ + ++LV TN+  RG+D+E+V++  N+D+P D D      TYL
Sbjct: 319 RGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSD------TYL 372

Query: 394 HRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLD 441
           HR+ R GRFG +GLA+  V  ++   ILN +Q+ F   I  L  D++D
Sbjct: 373 HRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISEL-PDEID 419


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  187 bits (475), Expect = 2e-47
 Identities = 112/342 (32%), Positives = 183/342 (53%), Gaps = 13/342 (3%)

Query: 99  LPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFY 158
           L  +++ Q++SG GKTA FVLA L Q+EP N     L +  T ELA Q  K  E+  K+ 
Sbjct: 80  LGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYM 139

Query: 159 PELKLAYAVRGNKLERGQKISEQ----IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 214
           P +K++    G  +++ +++ ++    +V+GTPG +L       F   K +K FVLDE D
Sbjct: 140 PSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSF-SLKNVKHFVLDECD 198

Query: 215 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TL 273
            M+     +     I R+ P   Q ++FSAT    +    +K + DP  + +  E + TL
Sbjct: 199 KMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTL 258

Query: 274 DTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLS 333
             ++QYYV      EK + L +L   +   Q +IF  + +    LA  L ++      + 
Sbjct: 259 HGLQQYYVKLKD-SEKNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIH 317

Query: 334 GEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYL 393
             M  E+R +  ++F++ + ++LV TN+  RG+D+E+V++V N+D+P D D      TYL
Sbjct: 318 RGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSD------TYL 371

Query: 394 HRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERL 435
           HR+ R GRFG +GLA+  V  ++   ILN +Q+ F   +  L
Sbjct: 372 HRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAEL 413


>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
           sapiens]
          Length = 824

 Score =  174 bits (442), Expect = 1e-43
 Identities = 113/337 (33%), Positives = 178/337 (52%), Gaps = 16/337 (4%)

Query: 102 NLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPEL 161
           +LI Q++SGTGKT  F    L  +   N   Q L L+PT E+A+Q   VI  +G     L
Sbjct: 101 DLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGL 160

Query: 162 KLAYAVRGNKLERGQKISEQ--IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIAT 219
           +    + G  L + +   ++  I +G+PG +     +L +++P  I++F+LDEAD ++  
Sbjct: 161 ECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLI-ELDYLNPGSIRLFILDEADKLLEE 219

Query: 220 QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQY 279
              Q+Q   I   LP + QML  SAT+ + +     K + DP  ++L   + +L  +KQY
Sbjct: 220 GSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQY 279

Query: 280 YVLCSSR-------DEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALL 332
           Y + +S        +EK Q L  L+  I   QA++F +    A  LA  LS +G     +
Sbjct: 280 YKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECI 339

Query: 333 SGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETY 392
           SG M   QR   + + +    +VL++T++ +RGID E+V++V+N D+P+D       ETY
Sbjct: 340 SGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDW------ETY 393

Query: 393 LHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFN 429
           +HRIGR GRFG  GL V         N++ RI +  N
Sbjct: 394 MHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCN 430


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  174 bits (440), Expect = 2e-43
 Identities = 118/342 (34%), Positives = 189/342 (55%), Gaps = 16/342 (4%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 160
           ++++A++++GTGK+ A+++ +L +++      Q + + PT ELALQ  ++  Q+ K    
Sbjct: 134 RDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGG 193

Query: 161 LKLAYAVRGNKLERG-QKISE--QIVIGTPGTVLDWCSK-LKFIDPKKIKVFVLDEADVM 216
            K+     G  L     ++ +   +VI TPG +LD   K +  +D   +++ VLDEAD +
Sbjct: 194 AKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVD--HVQMIVLDEADKL 251

Query: 217 IATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTI 276
           ++    Q     I   LP+N Q+LL+SATF  SV KF    +  P  I L  EE TL  +
Sbjct: 252 LSQDFVQIME-DIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGV 309

Query: 277 KQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEM 336
            QYY   + R +K   L  L+  + I Q++IFC++ +    LA ++S+ G+    +  +M
Sbjct: 310 TQYYAYVTER-QKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKM 368

Query: 337 MVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRI 396
             E R  V   FR G  + LV T++  RGID++ V+VVINFD P         ETYLHRI
Sbjct: 369 RQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFP------KLAETYLHRI 422

Query: 397 GRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 438
           GR+GRFG  GLA+N++      N L  I+E    +I+ + ++
Sbjct: 423 GRSGRFGHLGLAINLITYDDRFN-LKSIEEQLGTEIKPIPSN 463


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  149 bits (375), Expect = 7e-36
 Identities = 99/346 (28%), Positives = 178/346 (51%), Gaps = 14/346 (4%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPE 160
           +++I  +++G+GKT AF L +L+ +    +    L L+PT ELA Q  +  E +G     
Sbjct: 62  RDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG- 120

Query: 161 LKLAYAVRG-NKLERGQKISEQ--IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMI 217
           ++ A  V G + + +   ++++  I+I TPG ++D     K  + + +K  V+DEAD  I
Sbjct: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEAD-RI 179

Query: 218 ATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIK 277
                + +  +I +++PR+ +  LFSAT    V K  +  + +P    +  + +T++ ++
Sbjct: 180 LNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239

Query: 278 QYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMM 337
           QYY+   S+  K   L  +   +     MIFC T       A  L   G     L G+M 
Sbjct: 240 QYYIFIPSKF-KDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMS 298

Query: 338 VEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIG 397
             +R   + +F+     +L+ T+V +RG+D+  V VV+NFD+P        ++ Y+HR+G
Sbjct: 299 QSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPT------HSKDYIHRVG 352

Query: 398 RTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 443
           RT R G+ G A+  V +++ + +  RI+    KK+    T D DE+
Sbjct: 353 RTARAGRSGKAITFV-TQYDVELFQRIEHLIGKKLPGFPTQD-DEV 396


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  143 bits (360), Expect = 4e-34
 Identities = 106/326 (32%), Positives = 169/326 (51%), Gaps = 18/326 (5%)

Query: 101 QNLIAQSQSGTGKTAAFVLAML------SQVEPANKYPQCLCLSPTYELALQTGKVIEQM 154
           +++I  +++G+GKTAAF+  ML       ++EP +  P  + + PT EL  Q     ++ 
Sbjct: 291 RDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDG-PIAVIVCPTRELCQQIHAECKRF 349

Query: 155 GKFYPELKLAYAVRGNKLERGQKISE--QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDE 212
           GK Y    +A    G+  E+ + + E  +IV+ TPG ++D   K K  + +++   V DE
Sbjct: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDE 408

Query: 213 ADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEET 272
           AD M    G + Q   I   +  + Q LLFSATF   + K A+ ++ DP  +      E 
Sbjct: 409 ADRMF-DMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEA 467

Query: 273 LDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT-ASWLAAELSKEGHQVAL 331
            + + Q   +  S   K+  L       T + +++   T+K  A  LA  L +EGH + L
Sbjct: 468 NEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGL 527

Query: 332 LSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNET 391
           L G+M   +R  VI  F++    VLV T+V ARG+D+  +  VIN+D+  D D      T
Sbjct: 528 LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID------T 581

Query: 392 YLHRIGRTGRFGKRGLAVNMVDSKHS 417
           + HRIGRTGR G++G+A  ++  K S
Sbjct: 582 HTHRIGRTGRAGEKGVAYTLLTPKDS 607


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  143 bits (360), Expect = 4e-34
 Identities = 106/326 (32%), Positives = 169/326 (51%), Gaps = 18/326 (5%)

Query: 101 QNLIAQSQSGTGKTAAFVLAML------SQVEPANKYPQCLCLSPTYELALQTGKVIEQM 154
           +++I  +++G+GKTAAF+  ML       ++EP +  P  + + PT EL  Q     ++ 
Sbjct: 291 RDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDG-PIAVIVCPTRELCQQIHAECKRF 349

Query: 155 GKFYPELKLAYAVRGNKLERGQKISE--QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDE 212
           GK Y    +A    G+  E+ + + E  +IV+ TPG ++D   K K  + +++   V DE
Sbjct: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDE 408

Query: 213 ADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEET 272
           AD M    G + Q   I   +  + Q LLFSATF   + K A+ ++ DP  +      E 
Sbjct: 409 ADRMF-DMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEA 467

Query: 273 LDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT-ASWLAAELSKEGHQVAL 331
            + + Q   +  S   K+  L       T + +++   T+K  A  LA  L +EGH + L
Sbjct: 468 NEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGL 527

Query: 332 LSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNET 391
           L G+M   +R  VI  F++    VLV T+V ARG+D+  +  VIN+D+  D D      T
Sbjct: 528 LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID------T 581

Query: 392 YLHRIGRTGRFGKRGLAVNMVDSKHS 417
           + HRIGRTGR G++G+A  ++  K S
Sbjct: 582 HTHRIGRTGRAGEKGVAYTLLTPKDS 607


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  141 bits (355), Expect = 1e-33
 Identities = 114/347 (32%), Positives = 171/347 (49%), Gaps = 39/347 (11%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVEP------------------ANKYPQCLCLSPTYE 142
           ++L+A +Q+G+GKTAAF+L +LSQ+                      +YP  L L+PT E
Sbjct: 216 RDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRE 275

Query: 143 LALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKL 197
           LA+Q   + E+  KF    ++   V     + GQ+I +      +++ TPG ++D   + 
Sbjct: 276 LAVQ---IYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERG 332

Query: 198 KFIDPKKIKVFVLDEADVMIATQGHQDQSIRI---QRMLPRNCQ-MLLFSATFEDSVWKF 253
           K I     K  VLDEAD M+   G + Q  RI     M P+  +  ++FSATF   +   
Sbjct: 333 K-IGLDFCKYLVLDEADRML-DMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQML 390

Query: 254 AQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRK 313
           A+  + +   + + R   T + I Q  V     D++   L  L    + +  ++F  T+K
Sbjct: 391 ARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKK 450

Query: 314 TASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSV 373
            A  L   L  EG+    + G+     R   + +FR GK  +LV T V ARG+D+  V  
Sbjct: 451 GADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRH 510

Query: 374 VINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNI 420
           VINFDLP       D E Y+HRIGRTGR G  GLA +  + K +MNI
Sbjct: 511 VINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFNEK-NMNI 550


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  141 bits (355), Expect = 1e-33
 Identities = 114/347 (32%), Positives = 171/347 (49%), Gaps = 39/347 (11%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVEP------------------ANKYPQCLCLSPTYE 142
           ++L+A +Q+G+GKTAAF+L +LSQ+                      +YP  L L+PT E
Sbjct: 216 RDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRE 275

Query: 143 LALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKL 197
           LA+Q   + E+  KF    ++   V     + GQ+I +      +++ TPG ++D   + 
Sbjct: 276 LAVQ---IYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERG 332

Query: 198 KFIDPKKIKVFVLDEADVMIATQGHQDQSIRI---QRMLPRNCQ-MLLFSATFEDSVWKF 253
           K I     K  VLDEAD M+   G + Q  RI     M P+  +  ++FSATF   +   
Sbjct: 333 K-IGLDFCKYLVLDEADRML-DMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQML 390

Query: 254 AQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRK 313
           A+  + +   + + R   T + I Q  V     D++   L  L    + +  ++F  T+K
Sbjct: 391 ARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKK 450

Query: 314 TASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSV 373
            A  L   L  EG+    + G+     R   + +FR GK  +LV T V ARG+D+  V  
Sbjct: 451 GADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRH 510

Query: 374 VINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNI 420
           VINFDLP       D E Y+HRIGRTGR G  GLA +  + K +MNI
Sbjct: 511 VINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFNEK-NMNI 550


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  139 bits (350), Expect = 5e-33
 Identities = 110/343 (32%), Positives = 167/343 (48%), Gaps = 38/343 (11%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVEP------------------ANKYPQCLCLSPTYE 142
           ++L+A +Q+G+GKTAAF+L +LSQ+                      +YP  L L+PT E
Sbjct: 218 RDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRE 277

Query: 143 LALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKL 197
           LA+Q   + E+  KF    ++   V     + GQ+I +      +++ TPG ++D   + 
Sbjct: 278 LAVQ---IYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERG 334

Query: 198 KFIDPKKIKVFVLDEADVMIATQGHQDQSIRI---QRMLPRNCQ-MLLFSATFEDSVWKF 253
           K I     K  VLDEAD M+   G + Q  RI     M P+  +  ++FSATF   +   
Sbjct: 335 K-IGLDFCKYLVLDEADRML-DMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQML 392

Query: 254 AQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRK 313
           A+  + +   + + R   T + I Q  V     D++   L  L      +  ++F  T+K
Sbjct: 393 ARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKK 452

Query: 314 TASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSV 373
            A  L   L  EG+    + G+     R   + +FR GK  +LV T V ARG+D+  V  
Sbjct: 453 GADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKH 512

Query: 374 VINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKH 416
           VINFDLP       D E Y+HRIGRTGR G  GLA +  + ++
Sbjct: 513 VINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFNERN 549


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  135 bits (341), Expect = 6e-32
 Identities = 106/350 (30%), Positives = 176/350 (50%), Gaps = 24/350 (6%)

Query: 107 SQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYA 166
           +++G+GKTAAFVL +L ++        CL L+PT ELA Q  +    +GK    LK    
Sbjct: 46  AKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLG-LKDCII 104

Query: 167 VRG-----NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQG 221
           V G       LE  +K    +VI TPG + D          KKI+  V+DEAD ++  QG
Sbjct: 105 VGGMDMVAQALELSRK--PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLE-QG 161

Query: 222 HQDQSIRIQRML---PRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQ 278
             D ++ ++ +L   P   Q LLFSAT  D++ +        P   + +    T++ + Q
Sbjct: 162 CTDFTVDLEAILAAVPARRQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQ 221

Query: 279 YYVLCSSRDEKFQALCNLYGAITIAQA----MIFCHTRKTASWLAAELSKEGHQVALLSG 334
            Y+L   +  K   L +L             +IF +T KT   L   L K       L  
Sbjct: 222 RYLLVPEK-VKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHS 280

Query: 335 EMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLH 394
            M  ++R A + +F+    ++L+ T+V +RG+D+  V VVIN + P    G P  + Y+H
Sbjct: 281 MMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTP----GLP--KIYIH 334

Query: 395 RIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIE 444
           R+GRT R G++G A+ +V +++ +++++ I+E   KK+E    ++ + ++
Sbjct: 335 RVGRTARAGRQGQAITLV-TQYDIHLVHAIEEQIKKKLEEFSVEEAEVLQ 383


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  133 bits (335), Expect = 3e-31
 Identities = 114/378 (30%), Positives = 184/378 (48%), Gaps = 37/378 (9%)

Query: 92  KSFEELRLPQNLIAQSQSGTGKTAAFVLAMLSQVE------PANKYPQCLCLSPTYELAL 145
           K+F  +   ++LIAQ+++GTGKT +F + ++ ++          + PQ L L+PT ELA 
Sbjct: 215 KTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELAN 274

Query: 146 QTGKVIEQMGKFYPELKLAYAV------RGNKLERGQKISEQIVIGTPGTVLDWCSKLKF 199
           Q  K    + K     KL+ A        G + ER  +    I++GTPG + D     K 
Sbjct: 275 QVSKDFSDITK-----KLSVACFYGGTPYGGQFER-MRNGIDILVGTPGRIKDHIQNGK- 327

Query: 200 IDPKKIKVFVLDEADVMI----ATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 255
           +D  K+K  VLDE D M+    A Q  +  S+  ++    N Q LLFSAT    V+  A+
Sbjct: 328 LDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAK 387

Query: 256 KVVPDP-NVIKL--KREEETLDTIKQYYVLC--SSRDEKFQALCNLYGAITIAQAMIFCH 310
           K +      + L  K+ ++T  T++   + C  + R      +  +Y      + +IFC 
Sbjct: 388 KYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQ-GRTIIFCE 446

Query: 311 TRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQ 370
           T+K A  L+   S        L G++  +QR   ++ FR G   VLV TNV ARG+D+ +
Sbjct: 447 TKKEAQELSQN-SAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPE 505

Query: 371 VSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNK 430
           V +VI    P       D E+Y+HR GRTGR G+ G+ +     K    ++ ++++    
Sbjct: 506 VDLVIQSSPP------KDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLV-QVEQKAGI 558

Query: 431 KIERLDTDDLDEIEKIAN 448
           K +R+      EI K ++
Sbjct: 559 KFKRIGVPSATEIIKASS 576


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  132 bits (331), Expect = 8e-31
 Identities = 101/322 (31%), Positives = 161/322 (50%), Gaps = 16/322 (4%)

Query: 99  LPQNLIAQSQSGTGKTAAFVLAMLSQV--EPANK-YPQCLCLSPTYELALQTGKVIEQMG 155
           L +++ A + +GTGKTAAF L +L ++  +P      + L L PT EL +Q   V  Q+ 
Sbjct: 254 LGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLA 313

Query: 156 KFYPELKLAYAVRG---NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDE 212
           +F   +    AV G      E   + +  I+I TPG ++D            I+V +LDE
Sbjct: 314 QFC-NITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDE 372

Query: 213 ADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEET 272
           AD M+  +  ++Q   I RM   + Q +LFSAT  D V   A   + +P  I +    + 
Sbjct: 373 ADRML-DEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDV 431

Query: 273 LDTIKQYYV-LCSSRDEKFQALCNLYGAITIAQ-AMIFCHTRKTASWLAAELSKEGHQVA 330
              ++Q ++ +  +R+   +A+       T     M+F  T+K A  +   L   G QV 
Sbjct: 432 APFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVG 491

Query: 331 LLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNE 390
            L G +   QR   + RF++ +  +LV T+V ARG+D+E V  VINF +P         +
Sbjct: 492 ELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMP------NTIK 545

Query: 391 TYLHRIGRTGRFGKRGLAVNMV 412
            Y+HR+GRT R G+ G +V++V
Sbjct: 546 HYVHRVGRTARAGRAGRSVSLV 567


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  129 bits (323), Expect = 7e-30
 Identities = 93/323 (28%), Positives = 169/323 (52%), Gaps = 17/323 (5%)

Query: 99  LPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFY 158
           L ++++A + +G+GKTAAF+L ++ +    +K P  L L+PT ELA+Q  +  +++    
Sbjct: 239 LGRDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGL 298

Query: 159 PELKLAYAVRG----NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 214
           P +K    V G     +L R Q+   +++I TPG +LD   K   ++   +K+ V+DEAD
Sbjct: 299 PRMKTVLLVGGLPLPPQLYRLQQ-HVKVIIATPGRLLD-IIKQSSVELCGVKIVVVDEAD 356

Query: 215 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLD 274
            M+   G Q Q + I   +P +CQ +L SAT   S+ + A +++ +P  I    +     
Sbjct: 357 TML-KMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCA 415

Query: 275 TIKQ--YYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK-EGHQVAL 331
            ++Q   +V   ++ +K   + N    +     ++F   +  A  L+  + K  G +   
Sbjct: 416 NVRQIILWVEDPAKKKKLFEILN-DKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSIS 474

Query: 332 LSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNET 391
           +  E    +R  +++   EG  +V+V+T V  RG+D+  V +V+NFD+P   D       
Sbjct: 475 IHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMD------E 528

Query: 392 YLHRIGRTGRFGKRGLAVNMVDS 414
           Y+H+IGR GR G+ G A+  +++
Sbjct: 529 YVHQIGRVGRLGQNGTAITFINN 551


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  126 bits (317), Expect = 3e-29
 Identities = 104/356 (29%), Positives = 169/356 (47%), Gaps = 34/356 (9%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVE-----PANKYPQCLCLSPTYELALQTGKVIEQMG 155
           ++++  +Q+G+GKT A++L  +  +           P CL L+PT ELA Q  +V +  G
Sbjct: 209 RDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYG 268

Query: 156 KFYPELKLAYAVRG-------NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVF 208
           K    LK      G         LERG     +I I TPG ++D+    K  + ++    
Sbjct: 269 KC-SRLKSTCIYGGAPKGPQIRDLERGV----EICIATPGRLIDFLESGK-TNLRRCTYL 322

Query: 209 VLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKR 268
           VLDEAD M+   G + Q  +I   +  + Q L++SAT+   V + A+  + D   I +  
Sbjct: 323 VLDEADRML-DMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGN 381

Query: 269 EEETLD-TIKQYYVLC--SSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKE 325
            E + +  I Q   +C  S +D K   L     A    + +IF  T++    L   + ++
Sbjct: 382 LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRD 441

Query: 326 GHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDG 385
           G     + G+    +R  V+  FR GK  +L+ T+V +RG+DVE V  VIN+D P     
Sbjct: 442 GWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYP----- 496

Query: 386 NPDNETYLHRIGRTGRFGKRGLAV------NMVDSKHSMNILNRIQEHFNKKIERL 435
              +E Y+HRIGRT R   +G A       N+  ++  + +L    +  N K+ +L
Sbjct: 497 -NSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQL 551


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  126 bits (317), Expect = 3e-29
 Identities = 104/356 (29%), Positives = 169/356 (47%), Gaps = 34/356 (9%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVE-----PANKYPQCLCLSPTYELALQTGKVIEQMG 155
           ++++  +Q+G+GKT A++L  +  +           P CL L+PT ELA Q  +V +  G
Sbjct: 209 RDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYG 268

Query: 156 KFYPELKLAYAVRG-------NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVF 208
           K    LK      G         LERG     +I I TPG ++D+    K  + ++    
Sbjct: 269 KC-SRLKSTCIYGGAPKGPQIRDLERGV----EICIATPGRLIDFLESGK-TNLRRCTYL 322

Query: 209 VLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKR 268
           VLDEAD M+   G + Q  +I   +  + Q L++SAT+   V + A+  + D   I +  
Sbjct: 323 VLDEADRML-DMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGN 381

Query: 269 EEETLD-TIKQYYVLC--SSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKE 325
            E + +  I Q   +C  S +D K   L     A    + +IF  T++    L   + ++
Sbjct: 382 LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRD 441

Query: 326 GHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDG 385
           G     + G+    +R  V+  FR GK  +L+ T+V +RG+DVE V  VIN+D P     
Sbjct: 442 GWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYP----- 496

Query: 386 NPDNETYLHRIGRTGRFGKRGLAV------NMVDSKHSMNILNRIQEHFNKKIERL 435
              +E Y+HRIGRT R   +G A       N+  ++  + +L    +  N K+ +L
Sbjct: 497 -NSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQL 551


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  125 bits (315), Expect = 6e-29
 Identities = 121/423 (28%), Positives = 199/423 (47%), Gaps = 57/423 (13%)

Query: 10  VDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSN 69
           +DE E  ++ +S+L         DT+      N   E    E+KE             SN
Sbjct: 101 IDEYEKKSKRVSSL---------DTSTHKSSDNKLEETLTREQKEGAF----------SN 141

Query: 70  LVDNTNQVEVLQRDPNSPLY--SVKSFEELRLPQNLIAQSQSGTGKTAAFVLAMLSQVE- 126
              +   +++L+    + L+   VK+F  +   ++LIAQ+++GTGKT +F + ++ +++ 
Sbjct: 142 FPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQR 201

Query: 127 -----PANKYPQCLCLSPTYELALQTGKVIEQMGK------FYPELKLAYAVRGNKLERG 175
                  ++ P+ L L+PT ELA Q  K  + + +      FY     +Y  + N +  G
Sbjct: 202 NQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVACFYGGT--SYQSQINHIRNG 259

Query: 176 QKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMI----ATQGHQDQSIRIQR 231
                 I++GTPG + D     + +D  K++  VLDE D M+    A Q         + 
Sbjct: 260 I----DILVGTPGRIKDHLQSGR-LDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKT 314

Query: 232 MLPRNCQMLLFSATFEDSVWKFAQKVVPDP-NVIKL--KREEETLDTIKQYYVLC--SSR 286
               N Q LLFSAT    V+K A+K +      + L  K  ++   T++   + C  S R
Sbjct: 315 DSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQR 374

Query: 287 DEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIE 346
                 +  +Y   +  +A+IFC T+K  + +A     +      L G++   QR   ++
Sbjct: 375 PAVIGDVLQVYSG-SEGRAIIFCETKKNVTEMAMNPHIK-QNAQCLHGDIAQSQREITLK 432

Query: 347 RFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRG 406
            FREG  KVLV TNV ARG+D+ +V +VI    P       D E+Y+HR GRTGR G+ G
Sbjct: 433 GFREGSFKVLVATNVAARGLDIPEVDLVIQSSPP------QDVESYIHRSGRTGRAGRTG 486

Query: 407 LAV 409
           + +
Sbjct: 487 ICI 489


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  124 bits (312), Expect = 1e-28
 Identities = 105/330 (31%), Positives = 163/330 (49%), Gaps = 27/330 (8%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVE----PANKY-----PQCLCLSPTYELALQTGKVI 151
           ++L+A +Q+G+GKTAAF+L +L+ +      A+++     P+C+ ++PT EL  Q   + 
Sbjct: 326 RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQ---IY 382

Query: 152 EQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIK 206
            +  KF     +   V     + G  I +      I+  TPG ++D   K K I  K+IK
Sbjct: 383 LEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIK 441

Query: 207 VFVLDEADVMIATQ-GHQDQSIRIQRMLP--RNCQMLLFSATFEDSVWKFAQKVVPDPNV 263
             VLDEAD M+    G + + +     +P     Q L+FSATF + + + A + +    +
Sbjct: 442 YLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYL 501

Query: 264 IKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELS 323
                +        Q  VL   +  K + L  +   I   + M+F  T+K A ++A  L 
Sbjct: 502 FVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLC 561

Query: 324 KEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDK 383
           +E      + G+    +R   +  FR GK  VLV T+V ARG+D+E V  VINFDLP   
Sbjct: 562 QEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTI 621

Query: 384 DGNPDNETYLHRIGRTGRFGKRGLAVNMVD 413
           D       Y+HRIGRTGR G  G A++  D
Sbjct: 622 D------EYVHRIGRTGRCGNTGRAISFFD 645


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  124 bits (312), Expect = 1e-28
 Identities = 105/330 (31%), Positives = 163/330 (49%), Gaps = 27/330 (8%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVE----PANKY-----PQCLCLSPTYELALQTGKVI 151
           ++L+A +Q+G+GKTAAF+L +L+ +      A+++     P+C+ ++PT EL  Q   + 
Sbjct: 326 RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQ---IY 382

Query: 152 EQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIK 206
            +  KF     +   V     + G  I +      I+  TPG ++D   K K I  K+IK
Sbjct: 383 LEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIK 441

Query: 207 VFVLDEADVMIATQ-GHQDQSIRIQRMLP--RNCQMLLFSATFEDSVWKFAQKVVPDPNV 263
             VLDEAD M+    G + + +     +P     Q L+FSATF + + + A + +    +
Sbjct: 442 YLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYL 501

Query: 264 IKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELS 323
                +        Q  VL   +  K + L  +   I   + M+F  T+K A ++A  L 
Sbjct: 502 FVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLC 561

Query: 324 KEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDK 383
           +E      + G+    +R   +  FR GK  VLV T+V ARG+D+E V  VINFDLP   
Sbjct: 562 QEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTI 621

Query: 384 DGNPDNETYLHRIGRTGRFGKRGLAVNMVD 413
           D       Y+HRIGRTGR G  G A++  D
Sbjct: 622 D------EYVHRIGRTGRCGNTGRAISFFD 645


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  124 bits (312), Expect = 1e-28
 Identities = 105/330 (31%), Positives = 163/330 (49%), Gaps = 27/330 (8%)

Query: 101 QNLIAQSQSGTGKTAAFVLAMLSQVE----PANKY-----PQCLCLSPTYELALQTGKVI 151
           ++L+A +Q+G+GKTAAF+L +L+ +      A+++     P+C+ ++PT EL  Q   + 
Sbjct: 292 RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQ---IY 348

Query: 152 EQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIK 206
            +  KF     +   V     + G  I +      I+  TPG ++D   K K I  K+IK
Sbjct: 349 LEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIK 407

Query: 207 VFVLDEADVMIATQ-GHQDQSIRIQRMLP--RNCQMLLFSATFEDSVWKFAQKVVPDPNV 263
             VLDEAD M+    G + + +     +P     Q L+FSATF + + + A + +    +
Sbjct: 408 YLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYL 467

Query: 264 IKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELS 323
                +        Q  VL   +  K + L  +   I   + M+F  T+K A ++A  L 
Sbjct: 468 FVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLC 527

Query: 324 KEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDK 383
           +E      + G+    +R   +  FR GK  VLV T+V ARG+D+E V  VINFDLP   
Sbjct: 528 QEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTI 587

Query: 384 DGNPDNETYLHRIGRTGRFGKRGLAVNMVD 413
           D       Y+HRIGRTGR G  G A++  D
Sbjct: 588 D------EYVHRIGRTGRCGNTGRAISFFD 611


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  122 bits (307), Expect = 5e-28
 Identities = 98/350 (28%), Positives = 172/350 (49%), Gaps = 32/350 (9%)

Query: 102 NLIAQSQSGTGKTAAFV------LAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMG 155
           +LI  +Q+GTGKT  ++      L +   ++     P  L L+PT ELALQ   V  +  
Sbjct: 281 DLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQ---VEGECC 337

Query: 156 KF-YPELKLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIKVFV 209
           K+ Y  L+      G    R ++I E      I+I TPG + D      F++ K I   V
Sbjct: 338 KYSYKGLRSVCVYGGGN--RDEQIEELKKGVDIIIATPGRLND-LQMSNFVNLKNITYLV 394

Query: 210 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 269
           LDEAD M+   G + Q ++I   +  + Q ++ SAT+  SV + AQ  + +P ++ +   
Sbjct: 395 LDEADKML-DMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTL 453

Query: 270 E-ETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQ 328
           +   + ++KQ  ++ +  ++       L    +  + ++F   +  A  L+++L      
Sbjct: 454 DLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNIS 513

Query: 329 VALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPD 388
           V  L G+     R   +E F+ GK ++L+ T++ +RG+DV  V+ V NFD P       +
Sbjct: 514 VESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFP------RN 567

Query: 389 NETYLHRIGRTGRFGKRGLAVNMVD------SKHSMNILNRIQEHFNKKI 432
            E Y+HRIGRTGR G+ G+++  +       +   +NIL R  +   +++
Sbjct: 568 IEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEEL 617


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,807,240
Number of Sequences: 37866
Number of extensions: 666751
Number of successful extensions: 2604
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 2357
Number of HSP's gapped (non-prelim): 140
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.