Guide to the Human Genome
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Search of human proteins with 61743957

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61743957 apolipoprotein B mRNA editing enzyme [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61743957 apolipoprotein B mRNA editing enzyme [Homo sapiens]       518   e-147
gi|22907025 apolipoprotein B mRNA editing enzyme, catalytic poly...    91   9e-19
gi|13399304 apolipoprotein B mRNA editing enzyme, catalytic poly...    88   6e-18
gi|22907044 apolipoprotein B mRNA editing enzyme, catalytic poly...    88   7e-18
gi|10190700 activation-induced cytidine deaminase [Homo sapiens]       86   3e-17
gi|187608816 apolipoprotein B mRNA editing enzyme, catalytic pol...    84   8e-17
gi|22907039 apolipoprotein B mRNA editing enzyme, catalytic poly...    83   2e-16
gi|33147089 apolipoprotein B mRNA editing enzyme, catalytic poly...    71   9e-13
gi|21955158 phorbolin 1 [Homo sapiens]                                 71   9e-13
gi|5802978 apolipoprotein B mRNA editing enzyme, catalytic polyp...    64   1e-10
gi|44888831 apolipoprotein B [Homo sapiens]                            31   0.81 
gi|32880199 makorin ring finger protein 2 [Homo sapiens]               30   1.8  
gi|55925608 kelch-like 21 [Homo sapiens]                               29   4.0  
gi|31542835 galactose-3-O-sulfotransferase 4 [Homo sapiens]            28   6.9  

>gi|61743957 apolipoprotein B mRNA editing enzyme [Homo sapiens]
          Length = 236

 Score =  518 bits (1334), Expect = e-147
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MTSEKGPSTGDPTLRRRIEPWEFDVFYDPRELRKEACLLYEIKWGMSRKIWRSSGKNTTN 60
           MTSEKGPSTGDPTLRRRIEPWEFDVFYDPRELRKEACLLYEIKWGMSRKIWRSSGKNTTN
Sbjct: 1   MTSEKGPSTGDPTLRRRIEPWEFDVFYDPRELRKEACLLYEIKWGMSRKIWRSSGKNTTN 60

Query: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF 120
           HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF
Sbjct: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF 120

Query: 121 WHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFVNYPPGDEAHWPQYPPLWMMLYAL 180
           WHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFVNYPPGDEAHWPQYPPLWMMLYAL
Sbjct: 121 WHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFVNYPPGDEAHWPQYPPLWMMLYAL 180

Query: 181 ELHCIILSLPPCLKISRRWQNHLTFFRLHLQNCHYQTIPPHILLATGLIHPSVAWR 236
           ELHCIILSLPPCLKISRRWQNHLTFFRLHLQNCHYQTIPPHILLATGLIHPSVAWR
Sbjct: 181 ELHCIILSLPPCLKISRRWQNHLTFFRLHLQNCHYQTIPPHILLATGLIHPSVAWR 236


>gi|22907025 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3B [Homo sapiens]
          Length = 382

 Score = 90.9 bits (224), Expect = 9e-19
 Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 17/162 (10%)

Query: 11  DPTLRRRIEPWEFDVFYDPREL------RKEACLLYE--IKWGMSRKIWRSS---GK--- 56
           +P +R  +E    D FYD  E       R    L YE  IK G S  +W +    G+   
Sbjct: 2   NPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVYF 61

Query: 57  NTTNHVEVNFIKKFTSERDFHPSMSC-SITWFLSWSPCWECSQAIREFLSRHPGVTLVIY 115
               H E+ F+  F   +   P+  C  ITWF+SW+PC +C   + EFLS HP VTL I 
Sbjct: 62  KPQYHAEMCFLSWFCGNQ--LPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTIS 119

Query: 116 VARLFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157
            ARL+++ ++  R+ L  L  +G  + IM   E+ +CW NFV
Sbjct: 120 AARLYYYWERDYRRALCRLSQAGARVTIMDYEEFAYCWENFV 161



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 4/99 (4%)

Query: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPC--WECSQAIREFLSRHPGVTLVIYVAR 118
           H E+ F+    S +   P+    +TWF+SWSPC  W C+  +R FL  +  V L I+ AR
Sbjct: 253 HAELRFLDLVPSLQ-LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAAR 311

Query: 119 LFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157
           ++   D   ++ L+ L ++G  + IM   E+ +CW  FV
Sbjct: 312 IY-DYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFV 349


>gi|13399304 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3G [Homo sapiens]
          Length = 384

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 11/159 (6%)

Query: 33  RKEACLLYEIKW-GMSR-----KIWRSSGKNTTN-HVEVNFIKKFTSERDFHPSMSCSIT 85
           R    L YE+K  G SR     KI+R    +    H E+ F   F+  R  H      +T
Sbjct: 30  RNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVT 89

Query: 86  WFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLFWHMDQQNRQGLRDLVNS----GVTI 141
           W++SWSPC +C++ +  FL+  P VTL I+VARL++  D   ++ LR L         T+
Sbjct: 90  WYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATM 149

Query: 142 QIMRASEYYHCWRNFVNYPPGDEAHWPQYPPLWMMLYAL 180
           +IM   E+ HCW  FV         W   P  +++L+ +
Sbjct: 150 KIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIM 188



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 47/154 (30%), Positives = 77/154 (50%), Gaps = 22/154 (14%)

Query: 19  EPW-----EFDVFYDPRELRKEACLLYEIKWG-MSRKIWRSSGKNTTNHVEVNFIK---- 68
           EPW     E  + Y+   +  +  +L   + G +  +     G     H E+ F+     
Sbjct: 209 EPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPF 268

Query: 69  -KFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLFWHMDQQN 127
            K   ++D+       +T F SWSPC+ C+Q + +F+S++  V+L I+ AR++   D Q 
Sbjct: 269 WKLDLDQDYR------VTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIY---DDQG 319

Query: 128 R--QGLRDLVNSGVTIQIMRASEYYHCWRNFVNY 159
           R  +GLR L  +G  I IM  SE+ HCW  FV++
Sbjct: 320 RCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDH 353


>gi|22907044 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3F isoform a [Homo sapiens]
          Length = 373

 Score = 87.8 bits (216), Expect = 7e-18
 Identities = 42/117 (35%), Positives = 67/117 (57%), Gaps = 4/117 (3%)

Query: 42  IKWGMSRKIWRSSGKNTTN-HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAI 100
           + W   R ++R+     T+ H E  F+  F  +    P+ +  +TW+ SWSPC EC+  +
Sbjct: 231 VSW--KRGVFRNQVDPETHCHAERCFLSWFCDDI-LSPNTNYEVTWYTSWSPCPECAGEV 287

Query: 101 REFLSRHPGVTLVIYVARLFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157
            EFL+RH  V L I+ ARL++  D   ++GLR L   G +++IM   ++ +CW NFV
Sbjct: 288 AEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFV 344



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 50/133 (37%), Positives = 73/133 (54%), Gaps = 10/133 (7%)

Query: 33  RKEACLLYEIKW-GMSR-----KIWRSSG-KNTTNHVEVNFIKKFTSERDFHPSMSC-SI 84
           R    L YE+K  G SR     KI+R        +H E+ F+  F   +   P+  C  I
Sbjct: 30  RNTVWLCYEVKTKGPSRPRLDAKIFRGQVYSQPEHHAEMCFLSWFCGNQ--LPAYKCFQI 87

Query: 85  TWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLFWHMDQQNRQGLRDLVNSGVTIQIM 144
           TWF+SW+PC +C   + EFL+ HP VTL I  ARL+++ ++  R+ L  L  +G  ++IM
Sbjct: 88  TWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIM 147

Query: 145 RASEYYHCWRNFV 157
              E+ +CW NFV
Sbjct: 148 DDEEFAYCWENFV 160


>gi|10190700 activation-induced cytidine deaminase [Homo sapiens]
          Length = 198

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 39/98 (39%), Positives = 64/98 (65%), Gaps = 2/98 (2%)

Query: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF 120
           HVE+ F++ + S+ D  P     +TWF SWSPC++C++ + +FL  +P ++L I+ ARL+
Sbjct: 56  HVELLFLR-YISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLY 114

Query: 121 WHMDQQ-NRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157
           +  D++   +GLR L  +GV I IM   +Y++CW  FV
Sbjct: 115 FCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFV 152


>gi|187608816 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3D [Homo sapiens]
          Length = 386

 Score = 84.3 bits (207), Expect = 8e-17
 Identities = 57/173 (32%), Positives = 79/173 (45%), Gaps = 27/173 (15%)

Query: 11  DPTLRRRIEPWEFDVFYDPREL------RKEACLLYE--IKWGMSRKIW----------- 51
           +P +R  +E    D FYD  E       R    L YE  IK G S  +W           
Sbjct: 2   NPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLP 61

Query: 52  -RSSGKNTT------NHVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFL 104
            R S           NH E+ F+  F   R    +    ITWF+SW+PC  C   + +FL
Sbjct: 62  KRQSNHRQEVYFRFENHAEMCFLSWFCGNR-LPANRRFQITWFVSWNPCLPCVVKVTKFL 120

Query: 105 SRHPGVTLVIYVARLFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157
           + HP VTL I  ARL+++ D+  R  L  L  +G  ++IM   ++ +CW NFV
Sbjct: 121 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFV 173



 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 1/97 (1%)

Query: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF 120
           H E  F+  F  +    P+ +  +TW+ SWSPC EC+  + EFL+RH  V L I+ ARL 
Sbjct: 262 HAERCFLSWFCDDI-LSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLC 320

Query: 121 WHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157
           +  D   ++GL  L   G +++IM   ++  CW+NFV
Sbjct: 321 YFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFV 357


>gi|22907039 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3C [Homo sapiens]
          Length = 190

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 1/97 (1%)

Query: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF 120
           H E  F+  F  +    P+    +TW+ SWSPC +C+  + EFL+RH  V L I+ ARL+
Sbjct: 66  HAERCFLSWFCDDI-LSPNTKYQVTWYTSWSPCPDCAGEVAEFLARHSNVNLTIFTARLY 124

Query: 121 WHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157
           +      ++GLR L   GV ++IM   ++ +CW NFV
Sbjct: 125 YFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFV 161


>gi|33147089 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3H [Homo sapiens]
          Length = 183

 Score = 70.9 bits (172), Expect = 9e-13
 Identities = 32/99 (32%), Positives = 56/99 (56%), Gaps = 1/99 (1%)

Query: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF 120
           H E+ FI +  S      +    +T +L+WSPC  C+  + +F+  H  + L I+ +RL+
Sbjct: 54  HAEICFINEIKS-MGLDETQCYQVTCYLTWSPCSSCAWELVDFIKAHDHLNLGIFASRLY 112

Query: 121 WHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFVNY 159
           +H  +  ++GLR L  S V +++M   E+  CW NFV++
Sbjct: 113 YHWCKPQQKGLRLLCGSQVPVEVMGFPEFADCWENFVDH 151


>gi|21955158 phorbolin 1 [Homo sapiens]
          Length = 199

 Score = 70.9 bits (172), Expect = 9e-13
 Identities = 49/172 (28%), Positives = 80/172 (46%), Gaps = 21/172 (12%)

Query: 4   EKGPSTGDPTLRRRIEPWEFDVFYDPRELRKEACLLYEI---------KWGMSRKIWRSS 54
           E  P++G    R  ++P  F   ++    R +  L YE+         K    R    + 
Sbjct: 2   EASPASGP---RHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQ 58

Query: 55  GKNTT-----NHVEVNFIKKFTSERDFHPSMSCSITWFLSWSPC--WECSQAIREFLSRH 107
            KN        H E+ F+    S +   P+    +TWF+SWSPC  W C+  +R FL  +
Sbjct: 59  AKNLLCGFYGRHAELRFLDLVPSLQ-LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN 117

Query: 108 PGVTLVIYVARLFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFVNY 159
             V L I+ AR++ + D   ++ L+ L ++G  + IM   E+ HCW  FV++
Sbjct: 118 THVRLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDH 168


>gi|5802978 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 2 [Homo sapiens]
          Length = 224

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 28/88 (31%), Positives = 52/88 (59%)

Query: 76  FHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLFWHMDQQNRQGLRDLV 135
           F P++  ++TW++S SPC  C+  I + LS+   + L+I V RLF   + + +  L+ L 
Sbjct: 111 FDPALRYNVTWYVSSSPCAACADRIIKTLSKTKNLRLLILVGRLFMWEEPEIQAALKKLK 170

Query: 136 NSGVTIQIMRASEYYHCWRNFVNYPPGD 163
            +G  ++IM+  ++ + W+NFV    G+
Sbjct: 171 EAGCKLRIMKPQDFEYVWQNFVEQEEGE 198


>gi|44888831 apolipoprotein B [Homo sapiens]
          Length = 367

 Score = 31.2 bits (69), Expect = 0.81
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 11/56 (19%)

Query: 91  SPCWE----CSQAIREFLSRHPGVTLVIYVARLFWHMDQQ------NRQGLRDLVN 136
           SPC E    C   +  FL  +PG+TL IY ++L+ H +        NR+ LR L +
Sbjct: 125 SPCNEANHCCISKMYNFLITYPGITLSIYFSQLY-HTEMDFPASAWNREALRSLAS 179


>gi|32880199 makorin ring finger protein 2 [Homo sapiens]
          Length = 416

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 6/119 (5%)

Query: 27  YDP--RELRKEACLL-YEIKWGMSRKIWRSSGKNTTNHVEVNFIKKFTSERDFHPSMSCS 83
           +DP  R+  ++ C+L +E +   +     S  K  +  +EV   K   SER F    +C+
Sbjct: 204 FDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCN 263

Query: 84  ITWFLSWSPCWECSQAIREFLSRHPGVTLVI---YVARLFWHMDQQNRQGLRDLVNSGV 139
            T+ LS    W C++     + +      VI    +  ++W  DQ  +  L +    G+
Sbjct: 264 HTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGM 322


>gi|55925608 kelch-like 21 [Homo sapiens]
          Length = 597

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 15/113 (13%)

Query: 93  CWECSQAIREFLSRHPGVTLVIYVARLFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHC 152
           C   + A + F+ RH G      + RL         + LR L + G+ +    A+ Y   
Sbjct: 150 CSGLASAAQRFILRHVGELGAEQLERL------PLARLLRYLRDDGLCVPKEEAA-YQLA 202

Query: 153 WRNFVNYPPGDEAHWPQ--------YPPLWMMLYALELHCIILSLPPCLKISR 197
            R     PP   AHWPQ        +   + +L  +E   ++   PPCL++ R
Sbjct: 203 LRWVRADPPRRAAHWPQLLEAVRLPFVRRFYLLAHVEAEPLVARCPPCLRLLR 255


>gi|31542835 galactose-3-O-sulfotransferase 4 [Homo sapiens]
          Length = 486

 Score = 28.1 bits (61), Expect = 6.9
 Identities = 18/79 (22%), Positives = 32/79 (40%), Gaps = 10/79 (12%)

Query: 87  FLSWSPCWECSQAIREFLSRHPGVTLVIYVARLFWHMDQQ----------NRQGLRDLVN 136
           F+ W   W  S      ++ +   +LV+    L W +D            ++QGL  + N
Sbjct: 286 FIQWGLAWLDSVFDLVMVAEYFDESLVLLADALCWGLDDVVGFMHNAQAGHKQGLSTVSN 345

Query: 137 SGVTIQIMRASEYYHCWRN 155
           SG+T +  + +     W N
Sbjct: 346 SGLTAEDRQLTARARAWNN 364


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.489 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,758,634
Number of Sequences: 37866
Number of extensions: 469795
Number of successful extensions: 1109
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1089
Number of HSP's gapped (non-prelim): 18
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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