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Search of human proteins with 61676091
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61676091 cyclin C isoform a [Homo sapiens]
(283 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61676091 cyclin C isoform a [Homo sapiens] 580 e-166
gi|61676093 cyclin C isoform b [Homo sapiens] 409 e-114
gi|150417989 cyclin K isoform 1 [Homo sapiens] 82 4e-16
gi|38176158 cyclin K isoform 2 [Homo sapiens] 82 4e-16
gi|88758580 cyclin L2 isoform A [Homo sapiens] 80 2e-15
gi|9945320 cyclin L1 [Homo sapiens] 79 4e-15
gi|17978469 cyclin T2 isoform b [Homo sapiens] 74 1e-13
gi|4502629 cyclin T2 isoform a [Homo sapiens] 74 1e-13
gi|17978466 cyclin T1 [Homo sapiens] 69 6e-12
gi|4502623 cyclin H [Homo sapiens] 67 1e-11
gi|196049382 family with sequence similarity 58, member A isofor... 64 1e-10
gi|196049384 family with sequence similarity 58, member A isofor... 63 3e-10
gi|157502165 family with sequence similarity 58 member B [Homo s... 57 2e-08
gi|221554518 cyclin L2 isoform D [Homo sapiens] 47 1e-05
gi|221554516 cyclin L2 isoform C [Homo sapiens] 47 1e-05
gi|88758578 cyclin L2 isoform B [Homo sapiens] 47 1e-05
gi|4502617 cyclin D2 [Homo sapiens] 34 0.13
gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens] 33 0.37
gi|47106067 transmembrane emp24 protein transport domain contain... 32 0.63
gi|161377472 cyclin A1 isoform c [Homo sapiens] 32 0.82
gi|161377470 cyclin A1 isoform c [Homo sapiens] 32 0.82
gi|161377468 cyclin A1 isoform b [Homo sapiens] 32 0.82
gi|4502611 cyclin A1 isoform a [Homo sapiens] 32 0.82
gi|16950655 cyclin D1 [Homo sapiens] 31 1.1
gi|210031154 zinc finger protein 541 [Homo sapiens] 31 1.1
gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo sap... 30 1.8
gi|24308408 Cdk5 and Abl enzyme substrate 1 isoform 1 [Homo sapi... 30 1.8
gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapi... 30 3.1
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] 30 3.1
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] 30 3.1
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 580 bits (1495), Expect = e-166
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ 60
MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ
Sbjct: 1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ 60
Query: 61 VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRF 120
VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRF
Sbjct: 61 VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRF 120
Query: 121 SYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV 180
SYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV
Sbjct: 121 SYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV 180
Query: 181 NDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQ 240
NDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQ
Sbjct: 181 NDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQ 240
Query: 241 WKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS 283
WKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
Sbjct: 241 WKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS 283
>gi|61676093 cyclin C isoform b [Homo sapiens]
Length = 198
Score = 409 bits (1051), Expect = e-114
Identities = 198/198 (100%), Positives = 198/198 (100%)
Query: 86 MAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLEL 145
MAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLEL
Sbjct: 1 MAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLEL 60
Query: 146 MDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVA 205
MDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVA
Sbjct: 61 MDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVA 120
Query: 206 CVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPN 265
CVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPN
Sbjct: 121 CVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPN 180
Query: 266 SEGEQGPNGSQNSSYSQS 283
SEGEQGPNGSQNSSYSQS
Sbjct: 181 SEGEQGPNGSQNSSYSQS 198
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 82.4 bits (202), Expect = 4e-16
Identities = 83/289 (28%), Positives = 127/289 (43%), Gaps = 31/289 (10%)
Query: 14 WILDKQDLLK--ERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKR 71
W DK+DL + + L +E Y + F I +G L L +AT +YF R
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARF---IFDVGTRLGLHYDTLATGIIYFHR 80
Query: 72 FYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAF---PKEF 128
FY +S K + C+FLA KVEE +I A S+L F PKE
Sbjct: 81 FYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD-IIKTARSLLNDVQFGQFGDDPKE- 138
Query: 129 PYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQ----DMGQEDMLLPLAWRIVNDTY 184
++ E LL+ + L V HPY+ LL+Y + D + L+ +AW VND+
Sbjct: 139 -----EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSL 193
Query: 185 RTDLCLLYPPFMIALACLHVACVVQQKDARQWFAE-----------LSVDMEKILEIIRV 233
T L L + P +IA+A +++A + + + ++W ++ V ++ + +I
Sbjct: 194 CTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQ 253
Query: 234 ILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQ 282
IL LY Q K L + P +P P Q SQ+S SQ
Sbjct: 254 ILDLYSQGKQ-QMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ 301
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 82.4 bits (202), Expect = 4e-16
Identities = 83/289 (28%), Positives = 127/289 (43%), Gaps = 31/289 (10%)
Query: 14 WILDKQDLLK--ERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKR 71
W DK+DL + + L +E Y + F I +G L L +AT +YF R
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARF---IFDVGTRLGLHYDTLATGIIYFHR 80
Query: 72 FYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAF---PKEF 128
FY +S K + C+FLA KVEE +I A S+L F PKE
Sbjct: 81 FYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD-IIKTARSLLNDVQFGQFGDDPKE- 138
Query: 129 PYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQ----DMGQEDMLLPLAWRIVNDTY 184
++ E LL+ + L V HPY+ LL+Y + D + L+ +AW VND+
Sbjct: 139 -----EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSL 193
Query: 185 RTDLCLLYPPFMIALACLHVACVVQQKDARQWFAE-----------LSVDMEKILEIIRV 233
T L L + P +IA+A +++A + + + ++W ++ V ++ + +I
Sbjct: 194 CTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQ 253
Query: 234 ILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQ 282
IL LY Q K L + P +P P Q SQ+S SQ
Sbjct: 254 ILDLYSQGKQ-QMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ 301
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 80.1 bits (196), Expect = 2e-15
Identities = 64/214 (29%), Positives = 105/214 (49%), Gaps = 13/214 (6%)
Query: 40 LQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSL--KSIDPVLMAPTCVFLASKV 97
L++ +IQA G L+L Q +AT V F+RF+ S S++ V MA CV LASK+
Sbjct: 77 LRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMA--CVHLASKI 134
Query: 98 EE----FGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVY 153
EE V N K +++ N I++ E +L+ + C+ V
Sbjct: 135 EEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVK 194
Query: 154 HPYRPLLQYVQ--DMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC---VV 208
HP++ ++ Y+Q + + L+ +W +ND+ RTD+ + + P IA AC+++A +
Sbjct: 195 HPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEI 254
Query: 209 QQKDARQWFAELSVDMEKILEIIRVILKLYEQWK 242
+ WF E+I EI IL+LY + K
Sbjct: 255 PLPNRPHWFLLFGATEEEIQEICLKILQLYARKK 288
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 79.0 bits (193), Expect = 4e-15
Identities = 60/216 (27%), Positives = 101/216 (46%), Gaps = 17/216 (7%)
Query: 40 LQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEE 99
L+I +IQA G L+L Q +AT V F RF+ S ++A C+ LASK+EE
Sbjct: 82 LRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEE 141
Query: 100 --------FGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLI 151
V + R + +T + + N +++ E +L+ + C+
Sbjct: 142 APRRIRDVINVFHHLRQLRGK----RTPSPLILDQNYINTKNQVIKAERRVLKELGFCVH 197
Query: 152 VYHPYRPLLQYVQ--DMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQ 209
V HP++ ++ Y+Q + + L+ AW +ND+ RT++ + + P IA AC+++A
Sbjct: 198 VKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARAL 257
Query: 210 Q---KDARQWFAELSVDMEKILEIIRVILKLYEQWK 242
Q WF E+I EI L+LY + K
Sbjct: 258 QIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKK 293
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 73.9 bits (180), Expect = 1e-13
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 26/216 (12%)
Query: 46 NVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSN 105
N+IQ +G+ L + Q I TA VY RFY +S + +++ T +FLA+KVEE
Sbjct: 42 NLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEE------ 95
Query: 106 TRLIAAATSVLKTRFSYAFPKE---------FPYRMNHILECEFYLLELMDCCLIVYHPY 156
V+K + P E + + ++ E +L+ + + + HP+
Sbjct: 96 --QARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH 153
Query: 157 RPLLQYVQDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC------VVQ 209
+++ Q + +D+ + N + T CL Y P +IA C+H+AC +
Sbjct: 154 TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPV 213
Query: 210 QKDARQW--FAELSVDMEKILEIIRVILKLYEQWKN 243
D + W + + +V +E + E+ L++ E+ N
Sbjct: 214 STDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPN 249
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 73.9 bits (180), Expect = 1e-13
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 26/216 (12%)
Query: 46 NVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSN 105
N+IQ +G+ L + Q I TA VY RFY +S + +++ T +FLA+KVEE
Sbjct: 42 NLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEE------ 95
Query: 106 TRLIAAATSVLKTRFSYAFPKE---------FPYRMNHILECEFYLLELMDCCLIVYHPY 156
V+K + P E + + ++ E +L+ + + + HP+
Sbjct: 96 --QARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH 153
Query: 157 RPLLQYVQDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC------VVQ 209
+++ Q + +D+ + N + T CL Y P +IA C+H+AC +
Sbjct: 154 TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPV 213
Query: 210 QKDARQW--FAELSVDMEKILEIIRVILKLYEQWKN 243
D + W + + +V +E + E+ L++ E+ N
Sbjct: 214 STDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPN 249
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 68.6 bits (166), Expect = 6e-12
Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 12/209 (5%)
Query: 46 NVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSN 105
N++Q +G+ L + Q I TA VY RFY S +AP +FLA+KVEE
Sbjct: 43 NLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEE-QPKKL 101
Query: 106 TRLIAAATSVLKTRFSYAFPKEFPY--RMNHILECEFYLLELMDCCLIVYHPYRPLLQYV 163
+I A + L + S + Y ++ ++ E +L+ + L + HP+ +++
Sbjct: 102 EHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCT 161
Query: 164 QDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC------VVQQKDARQW 216
Q + +D+ + N + T L Y P ++A C+H+AC + D + W
Sbjct: 162 QLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHW 221
Query: 217 --FAELSVDMEKILEIIRVILKLYEQWKN 243
+ + +V +E + E+ L++ E+ N
Sbjct: 222 WEYVDATVTLELLDELTHEFLQILEKTPN 250
>gi|4502623 cyclin H [Homo sapiens]
Length = 323
Score = 67.4 bits (163), Expect = 1e-11
Identities = 49/151 (32%), Positives = 72/151 (47%), Gaps = 17/151 (11%)
Query: 59 QQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118
+ V+ TA +YFKRFY S+ P ++ TC FLA KV+EF V S + S L
Sbjct: 77 RSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQ 136
Query: 119 RFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQD-------MGQEDM 171
+ + ILE E L++ ++ LIV++PYRP ++ D + ++
Sbjct: 137 EKA----------LEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEI 186
Query: 172 LLPLAWRIVNDTYRTDLCLLYPPFMIALACL 202
L A +N TD LLY P IAL +
Sbjct: 187 LRKTADDFLNRIALTDAYLLYTPSQIALTAI 217
>gi|196049382 family with sequence similarity 58, member A isoform 1
[Homo sapiens]
Length = 248
Score = 64.3 bits (155), Expect = 1e-10
Identities = 50/208 (24%), Positives = 95/208 (45%), Gaps = 17/208 (8%)
Query: 48 IQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTR 107
I G L +R IATA + +F+ +L + DP L+A + ++LA KVEE + +
Sbjct: 34 IMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDI 93
Query: 108 LIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDM- 166
+ + + F + I++CE +L ++ + HP++ LL Y+ +
Sbjct: 94 INVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQ 153
Query: 167 -------GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVV-------QQKD 212
Q + AW ++ D+Y LCL + IA+A L++A V + +
Sbjct: 154 NWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEA 213
Query: 213 ARQWFAELSVDMEK--ILEIIRVILKLY 238
+ W+ + D+ K I I+ ++++Y
Sbjct: 214 EKPWWQVFNDDLTKPIIDNIVSDLIQIY 241
>gi|196049384 family with sequence similarity 58, member A isoform 2
[Homo sapiens]
Length = 228
Score = 62.8 bits (151), Expect = 3e-10
Identities = 44/169 (26%), Positives = 78/169 (46%), Gaps = 8/169 (4%)
Query: 48 IQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTR 107
I G L +R IATA + +F+ +L + DP L+A + ++LA KVEE + +
Sbjct: 34 IMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDI 93
Query: 108 LIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDM- 166
+ + + F + I++CE +L ++ + HP++ LL Y+ +
Sbjct: 94 INVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQ 153
Query: 167 -------GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVV 208
Q + AW ++ D+Y LCL + IA+A L++A V
Sbjct: 154 NWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQV 202
>gi|157502165 family with sequence similarity 58 member B [Homo
sapiens]
Length = 252
Score = 56.6 bits (135), Expect = 2e-08
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 33/216 (15%)
Query: 48 IQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTR 107
I G L ++ IATA + +F+ L + DP L+A + ++LA KVEE +
Sbjct: 38 IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL----- 92
Query: 108 LIAAATSVLKTRFSYAFPKEFPYRM--------NHILECEFYLLELMDCCLIVYHPYRPL 159
A ++ Y P P + + I++ E +L ++ + HP++ L
Sbjct: 93 ---WAHDIISVSNRYFNPSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYL 149
Query: 160 LQYVQDM--------GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVV--- 208
L Y+ + Q + AW ++ D+Y LCL + IA+ L++A V
Sbjct: 150 LYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLALQVYGV 209
Query: 209 ----QQKDARQWFAELSVDMEK--ILEIIRVILKLY 238
+ + + W+ S D+ K I I+ ++++Y
Sbjct: 210 EVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIY 245
>gi|221554518 cyclin L2 isoform D [Homo sapiens]
Length = 227
Score = 47.4 bits (111), Expect = 1e-05
Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 8/131 (6%)
Query: 40 LQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSL--KSIDPVLMAPTCVFLASKV 97
L++ +IQA G L+L Q +AT V F+RF+ S S++ V MA CV LASK+
Sbjct: 77 LRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMA--CVHLASKI 134
Query: 98 EE----FGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVY 153
EE V N K +++ N I++ E +L+ + C+ V
Sbjct: 135 EEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVK 194
Query: 154 HPYRPLLQYVQ 164
HP++ ++ Y+Q
Sbjct: 195 HPHKIIVMYLQ 205
>gi|221554516 cyclin L2 isoform C [Homo sapiens]
Length = 236
Score = 47.4 bits (111), Expect = 1e-05
Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 8/131 (6%)
Query: 40 LQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSL--KSIDPVLMAPTCVFLASKV 97
L++ +IQA G L+L Q +AT V F+RF+ S S++ V MA CV LASK+
Sbjct: 77 LRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMA--CVHLASKI 134
Query: 98 EE----FGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVY 153
EE V N K +++ N I++ E +L+ + C+ V
Sbjct: 135 EEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVK 194
Query: 154 HPYRPLLQYVQ 164
HP++ ++ Y+Q
Sbjct: 195 HPHKIIVMYLQ 205
>gi|88758578 cyclin L2 isoform B [Homo sapiens]
Length = 226
Score = 47.4 bits (111), Expect = 1e-05
Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 8/131 (6%)
Query: 40 LQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSL--KSIDPVLMAPTCVFLASKV 97
L++ +IQA G L+L Q +AT V F+RF+ S S++ V MA CV LASK+
Sbjct: 77 LRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMA--CVHLASKI 134
Query: 98 EE----FGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVY 153
EE V N K +++ N I++ E +L+ + C+ V
Sbjct: 135 EEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVK 194
Query: 154 HPYRPLLQYVQ 164
HP++ ++ Y+Q
Sbjct: 195 HPHKIIVMYLQ 205
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 34.3 bits (77), Expect = 0.13
Identities = 41/169 (24%), Positives = 69/169 (40%), Gaps = 27/169 (15%)
Query: 53 EHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAA 112
E K ++V A Y RF A L+ C+FLASK++E ++ +L
Sbjct: 68 EEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYT 127
Query: 113 TSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDML 172
+ +K P+E +LE E +L + L P+ + ++ + Q+
Sbjct: 128 DNSIK-------PQE-------LLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREK 173
Query: 173 LPLAWRIVNDTYRTDLCL--------LYPPFMIALACLHVA-CVVQQKD 212
L L + +T + L +YPP MIA + A C +QQ +
Sbjct: 174 LSL----IRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDE 218
>gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens]
Length = 478
Score = 32.7 bits (73), Expect = 0.37
Identities = 31/150 (20%), Positives = 65/150 (43%), Gaps = 19/150 (12%)
Query: 26 QKDLKFLSEEEYWKLQIFFTNV------IQALGEHLKLRQQVIATATVYFKRFYARYSLK 79
+KD+ E++ +++ + + +++L E L +A A VYF++ + L
Sbjct: 341 KKDMNETFREKFPHVKLTLSKIRSLKREMRSLSEECSLEPVTVAMAYVYFEKLVLQGKLS 400
Query: 80 SIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECE 139
+ L A CV LA+K+ S+ R + K + F + ++ E
Sbjct: 401 KQNRKLCAGACVLLAAKIS-----SDLRKSGVTQLIDK------LEERFRFNRRDLIGFE 449
Query: 140 FYLLELMDCCLIVYHPYRPLLQYVQDMGQE 169
F +L ++ L +Y P +L + + + Q+
Sbjct: 450 FTVLVALE--LALYLPENQVLPHYRRLTQQ 477
>gi|47106067 transmembrane emp24 protein transport domain containing
8 [Homo sapiens]
Length = 325
Score = 32.0 bits (71), Expect = 0.63
Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
Query: 79 KSIDPVLMAPTCVFLASKVEEF----GVVSNTRLIAAATSVLKTR 119
+ + P LMAP C++ +KV+EF G N+RL+ V+ R
Sbjct: 150 RKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIR 194
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 31.6 bits (70), Expect = 0.82
Identities = 49/238 (20%), Positives = 90/238 (37%), Gaps = 28/238 (11%)
Query: 25 RQKDLKFLSEEEYWKLQIFFTNVIQAL--------GEHLKLRQQVIATATVYFKRFYARY 76
R+ +++ + Y K Q T ++ + GE KLR + + A + RF +
Sbjct: 176 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 235
Query: 77 SLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHIL 136
S+ L+ + LASK EE + + + Y +L
Sbjct: 236 SVLRGKLQLVGTAAMLLASKYEEIYPPEVD--------------EFVYITDDTYTKRQLL 281
Query: 137 ECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVN-DTYRTDLCLLYPPF 195
+ E LL+++ L V + LLQY++ G LA + D L Y P
Sbjct: 282 KMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPS 341
Query: 196 MIALACLHVACVVQQKDARQWFAELSVDME--KILEIIRVILKLYEQWKNFDERKEMA 251
+IA A C+ + ++ E + EI+ + +L++ + + R + A
Sbjct: 342 LIAAAAF---CLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQA 396
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 31.6 bits (70), Expect = 0.82
Identities = 49/238 (20%), Positives = 90/238 (37%), Gaps = 28/238 (11%)
Query: 25 RQKDLKFLSEEEYWKLQIFFTNVIQAL--------GEHLKLRQQVIATATVYFKRFYARY 76
R+ +++ + Y K Q T ++ + GE KLR + + A + RF +
Sbjct: 176 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 235
Query: 77 SLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHIL 136
S+ L+ + LASK EE + + + Y +L
Sbjct: 236 SVLRGKLQLVGTAAMLLASKYEEIYPPEVD--------------EFVYITDDTYTKRQLL 281
Query: 137 ECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVN-DTYRTDLCLLYPPF 195
+ E LL+++ L V + LLQY++ G LA + D L Y P
Sbjct: 282 KMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPS 341
Query: 196 MIALACLHVACVVQQKDARQWFAELSVDME--KILEIIRVILKLYEQWKNFDERKEMA 251
+IA A C+ + ++ E + EI+ + +L++ + + R + A
Sbjct: 342 LIAAAAF---CLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQA 396
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 31.6 bits (70), Expect = 0.82
Identities = 49/238 (20%), Positives = 90/238 (37%), Gaps = 28/238 (11%)
Query: 25 RQKDLKFLSEEEYWKLQIFFTNVIQAL--------GEHLKLRQQVIATATVYFKRFYARY 76
R+ +++ + Y K Q T ++ + GE KLR + + A + RF +
Sbjct: 219 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 278
Query: 77 SLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHIL 136
S+ L+ + LASK EE + + + Y +L
Sbjct: 279 SVLRGKLQLVGTAAMLLASKYEEIYPPEVD--------------EFVYITDDTYTKRQLL 324
Query: 137 ECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVN-DTYRTDLCLLYPPF 195
+ E LL+++ L V + LLQY++ G LA + D L Y P
Sbjct: 325 KMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPS 384
Query: 196 MIALACLHVACVVQQKDARQWFAELSVDME--KILEIIRVILKLYEQWKNFDERKEMA 251
+IA A C+ + ++ E + EI+ + +L++ + + R + A
Sbjct: 385 LIAAAAF---CLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQA 439
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 31.6 bits (70), Expect = 0.82
Identities = 49/238 (20%), Positives = 90/238 (37%), Gaps = 28/238 (11%)
Query: 25 RQKDLKFLSEEEYWKLQIFFTNVIQAL--------GEHLKLRQQVIATATVYFKRFYARY 76
R+ +++ + Y K Q T ++ + GE KLR + + A + RF +
Sbjct: 220 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 279
Query: 77 SLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHIL 136
S+ L+ + LASK EE + + + Y +L
Sbjct: 280 SVLRGKLQLVGTAAMLLASKYEEIYPPEVD--------------EFVYITDDTYTKRQLL 325
Query: 137 ECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVN-DTYRTDLCLLYPPF 195
+ E LL+++ L V + LLQY++ G LA + D L Y P
Sbjct: 326 KMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPS 385
Query: 196 MIALACLHVACVVQQKDARQWFAELSVDME--KILEIIRVILKLYEQWKNFDERKEMA 251
+IA A C+ + ++ E + EI+ + +L++ + + R + A
Sbjct: 386 LIAAAAF---CLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQA 440
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 31.2 bits (69), Expect = 1.1
Identities = 16/47 (34%), Positives = 25/47 (53%)
Query: 53 EHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEE 99
E K ++V A Y RF + +K L+ TC+F+ASK++E
Sbjct: 69 EEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE 115
>gi|210031154 zinc finger protein 541 [Homo sapiens]
Length = 1365
Score = 31.2 bits (69), Expect = 1.1
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 237 LYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNS 278
L Q K+ +ER + + K +PPP++ GE GP G S
Sbjct: 950 LQGQEKDGEERDSKESSQQRKRKKRPPPSTAGEPGPAGCHQS 991
>gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo
sapiens]
Length = 633
Score = 30.4 bits (67), Expect = 1.8
Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 26 QKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ-------VIATATVYFKRFYARYSL 78
+KD+ +E++ +++ + + E KL Q+ +A A VYF++ + L
Sbjct: 495 KKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKL 554
Query: 79 KSIDPVLMAPTCVFLASKV 97
+ L A CV LA+K+
Sbjct: 555 NKQNRKLCAGACVLLAAKI 573
>gi|24308408 Cdk5 and Abl enzyme substrate 1 isoform 1 [Homo
sapiens]
Length = 368
Score = 30.4 bits (67), Expect = 1.8
Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 26 QKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ-------VIATATVYFKRFYARYSL 78
+KD+ +E++ +++ + + E KL Q+ +A A VYF++ + L
Sbjct: 230 KKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKL 289
Query: 79 KSIDPVLMAPTCVFLASKV 97
+ L A CV LA+K+
Sbjct: 290 NKQNRKLCAGACVLLAAKI 308
>gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo
sapiens]
Length = 887
Score = 29.6 bits (65), Expect = 3.1
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 3/33 (9%)
Query: 253 ILSKMPKPKPPP---NSEGEQGPNGSQNSSYSQ 282
IL + PKP PPP N E +G G+Q+ Y +
Sbjct: 765 ILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQE 797
>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 29.6 bits (65), Expect = 3.1
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 5/55 (9%)
Query: 16 LDKQDLLKERQKDLKFLSEEEYWKLQ--IFFTNVIQALGEHLKLRQQVIATATVY 68
L KQ + E QK L F+S++EY+ Q + N+ + L + L++ AT TVY
Sbjct: 383 LQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGL---ITLQELQQATKTVY 434
>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 29.6 bits (65), Expect = 3.1
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 5/55 (9%)
Query: 16 LDKQDLLKERQKDLKFLSEEEYWKLQ--IFFTNVIQALGEHLKLRQQVIATATVY 68
L KQ + E QK L F+S++EY+ Q + N+ + L + L++ AT TVY
Sbjct: 383 LQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGL---ITLQELQQATKTVY 434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,282,465
Number of Sequences: 37866
Number of extensions: 477063
Number of successful extensions: 3230
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3159
Number of HSP's gapped (non-prelim): 58
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.