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Search of human proteins with 6005920
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005920 thyrotropin-releasing hormone [Homo sapiens]
(242 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005920 thyrotropin-releasing hormone [Homo sapiens] 503 e-143
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 47 1e-05
gi|148746195 trichohyalin [Homo sapiens] 44 2e-04
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 42 6e-04
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 41 8e-04
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 41 8e-04
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 41 8e-04
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 41 0.001
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 41 0.001
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 40 0.001
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 40 0.001
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 40 0.001
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 40 0.001
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 40 0.001
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 40 0.002
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 40 0.002
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 40 0.002
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 40 0.002
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 39 0.003
gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 39 0.003
gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 39 0.003
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 39 0.004
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.004
gi|61175239 transcription elongation factor A (SII)-like 5 [Homo... 39 0.004
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 39 0.005
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 39 0.005
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 39 0.005
gi|157694505 LINE-1 type transposase domain containing 1 [Homo s... 39 0.005
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 39 0.005
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 38 0.007
>gi|6005920 thyrotropin-releasing hormone [Homo sapiens]
Length = 242
Score = 503 bits (1295), Expect = e-143
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQ 60
MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQ
Sbjct: 1 MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQ 60
Query: 61 RLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRRE 120
RLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRRE
Sbjct: 61 RLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRRE 120
Query: 121 DEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDL 180
DEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDL
Sbjct: 121 DEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDL 180
Query: 181 MPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPL 240
MPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPL
Sbjct: 181 MPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPL 240
Query: 241 EE 242
EE
Sbjct: 241 EE 242
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 82 KRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRS 141
K++ K+E EE E EE EEEE +++ R+E E T+ +++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE- 59
Query: 142 PWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKR 191
K++ R+ + +R EEEEEEEE+EE+ E R+ K+
Sbjct: 60 --------KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 10/110 (9%)
Query: 82 KRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRS 141
K++ E EE E EEEEE+EG K + + + + + + + K + +R
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR- 62
Query: 142 PWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKR 191
KR+ ++ + + + EEEEEE+E EE +R+ KR
Sbjct: 63 --------KRKRKKKKEEEEREEEE-EEEEEEKEEEEKEEGRRRKKKKKR 103
Score = 34.7 bits (78), Expect = 0.077
Identities = 18/41 (43%), Positives = 26/41 (63%)
Query: 82 KRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDE 122
K++ +REEEEEE EE+EEEE K++ RR++E
Sbjct: 68 KKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108
Score = 32.3 bits (72), Expect = 0.38
Identities = 16/41 (39%), Positives = 24/41 (58%)
Query: 82 KRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDE 122
K + + EEEEEE +EEEE+E G K++ + E+E
Sbjct: 70 KEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 32.0 bits (71), Expect = 0.50
Identities = 18/60 (30%), Positives = 32/60 (53%)
Query: 82 KRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRS 141
KR+ K+++EEEE EEEEEEE K + R++ + + + K++ R++
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.5 bits (101), Expect = 2e-04
Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 20/122 (16%)
Query: 57 ENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHP 116
E QR + + Q + + +R+ ++ +EEE+G++E++E +R
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER--------RRSQE 867
Query: 117 GRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEER 176
RR+ + W ++ + +R+H YA P Q R K Q+ +EEEEE +R
Sbjct: 868 QRRDQKWRWQLEEERKRRRH-------TLYAKPALQEQLR-----KEQQLLQEEEEELQR 915
Query: 177 EE 178
EE
Sbjct: 916 EE 917
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/151 (25%), Positives = 68/151 (45%), Gaps = 12/151 (7%)
Query: 47 RQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEE--EEGVEEEE--- 101
R+ E+ L QRL+ +Q E + + + +RQ KRE+EE E+ ++ EE
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREE--ERRQQRLKREQEERLEQRLKREEVER 609
Query: 102 -EEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLAD 160
E+E KR+ P + + + +RQ RR + Q R +
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ----QERREQRLKREEEE 665
Query: 161 PKAQRSWEEEEEEEEREEDLMPEKRQHPGKR 191
+ ++ + E EEE RE++L E+++ +R
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARER 696
Score = 40.8 bits (94), Expect = 0.001
Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 23/182 (12%)
Query: 27 EAAQQEAVTAAEHPGLDDFLR--QVERLLFLRENIQRLQGDQGEHSASQ--IFQSDWLSK 82
E +Q+ + + L+ L+ +VERL QRL+ ++ E Q + + +
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 83 RQHPGKREEEE--EEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRR 140
RQ +RE++E E+ ++ EEEEE KR+H R ++ + Q + + R
Sbjct: 643 RQQQLRREQQERREQRLKREEEEER-LEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 141 SPW-------------LAYAVPKRQHPGRRLADPKAQRSWEEEE---EEEEREEDLMPEK 184
W Y+ P++Q RR + + +R E E +EEER E+
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 185 RQ 186
Q
Sbjct: 762 EQ 763
Score = 38.9 bits (89), Expect = 0.004
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 4/150 (2%)
Query: 46 LRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEG 105
LR+ ++L +E +R Q ++ + Q + ++Q ++EE E+ + E+EEE
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 106 GAVGPHKRQHPGRREDEASWSVDV---TQHKRQHPGRRSPWLAYAVP-KRQHPGRRLADP 161
+ Q RRE + + Q +R+ RR L +R+ RR
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 162 KAQRSWEEEEEEEEREEDLMPEKRQHPGKR 191
+ ++ E+EEE E+ E+R+ KR
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKR 449
Score = 38.1 bits (87), Expect = 0.007
Identities = 43/202 (21%), Positives = 77/202 (38%), Gaps = 35/202 (17%)
Query: 23 RAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSK 82
R +PE +++ + +E ++ +Q R QRL+ ++ E Q + + +
Sbjct: 622 REEPEEERRQQLLKSEEQ--EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 83 RQHPGKREEEEEEG--------------VEEEEEEEGGAVGPHKRQHPG----------- 117
R+ EEE+E+ +E E + V R+ G
Sbjct: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Query: 118 -RREDEASWSVDVTQHKRQHPG---RRSPWLAYAVPKRQHPGRRLADPKAQRSWEEE--- 170
RRE E W + H++Q R W A K + +RL+ R E
Sbjct: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799
Query: 171 -EEEEEREEDLMPEKRQHPGKR 191
EE ++RE+ +PE+ + +R
Sbjct: 800 AEERQQREQRFLPEEEEKEQRR 821
Score = 37.4 bits (85), Expect = 0.012
Identities = 31/144 (21%), Positives = 64/144 (44%), Gaps = 14/144 (9%)
Query: 50 ERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVG 109
+R LR+ ++LQ ++ + + + L K + R E +EE E++++
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE--EQQQQRLRREQQ 305
Query: 110 PHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEE 169
++Q RRE + + +R+ RR +R+ RR + + ++
Sbjct: 306 LRRKQEEERREQQ--------EERREQQERREQ----QEERREQQLRREQEERREQQLRR 353
Query: 170 EEEEEEREEDLMPEKRQHPGKRAL 193
E+EEE RE+ L E+ + ++ L
Sbjct: 354 EQEEERREQQLRREQEEERREQQL 377
Score = 36.6 bits (83), Expect = 0.020
Identities = 31/131 (23%), Positives = 59/131 (45%), Gaps = 20/131 (15%)
Query: 65 DQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRRE--DE 122
D+ + Q+ + + +R +R+ EEE +++EEE+ G +R+ R+ E
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 123 ASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMP 182
+ Q R+ P +R +RQ + +R EEEE ++ EE L+
Sbjct: 1084 EELQQEEEQLLREEPEKR---------RRQ---------ERERQCREEEELQQEEEQLLR 1125
Query: 183 EKRQHPGKRAL 193
E+R+ ++ L
Sbjct: 1126 EEREKRRRQEL 1136
Score = 35.8 bits (81), Expect = 0.034
Identities = 40/194 (20%), Positives = 79/194 (40%), Gaps = 38/194 (19%)
Query: 27 EAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGE------------------ 68
E ++ T P L + LR+ ++LL +E + LQ ++ E
Sbjct: 880 EERKRRRHTLYAKPALQEQLRKEQQLL--QEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Query: 69 HSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEE----EEGGAVGPHKRQHPGRREDEAS 124
Q+ + + +R+ +R+ +++ ++++EE EE +R+ R E+E
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 125 WSVDVTQHKRQHPGRRSPWLAYAVPK------------RQHPGRRLADPKAQRSWEEEEE 172
+ + + RR W K + RRL + +R + EEEE
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE--RERQYREEEE 1055
Query: 173 EEEREEDLMPEKRQ 186
++ EE L+ E+R+
Sbjct: 1056 LQQEEEQLLGEERE 1069
Score = 34.3 bits (77), Expect = 0.10
Identities = 33/156 (21%), Positives = 61/156 (39%), Gaps = 29/156 (18%)
Query: 30 QQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKR 89
++E + E + + E+L L R + + E ++ + L ++Q +R
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 90 EEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVP 149
E++EE ++E E Q RRE Q +R+ RR
Sbjct: 316 EQQEERREQQERRE----------QQEERREQ---------QLRREQEERR--------- 347
Query: 150 KRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKR 185
Q R + + ++ E+EEE RE+ L E++
Sbjct: 348 -EQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Score = 34.3 bits (77), Expect = 0.10
Identities = 35/159 (22%), Positives = 67/159 (42%), Gaps = 35/159 (22%)
Query: 43 DDFLRQVERLLFLRENIQRLQGDQGEH--------SASQIFQSDWLSKRQHPGKREEEEE 94
D+ ++ E+LL +RLQ + ++ Q+ + ++R+ +R+ +E
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 95 EGVEEEEE----EEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPK 150
E +++EEE EE +R+ R E+E + + + RR
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ--------- 1134
Query: 151 RQHPGRRLADPKAQRSWEEEEEEEEREEDLM---PEKRQ 186
+ +R + EEEE ++ EE L+ PEKR+
Sbjct: 1135 -----------ELERQYREEEEVQQEEEQLLREEPEKRR 1162
Score = 33.9 bits (76), Expect = 0.13
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 13/149 (8%)
Query: 47 RQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEE-EEGVEEEEEEEG 105
+Q+ R LR Q+L+ +Q E Q + + +R+ KRE+EE + ++ EEE E
Sbjct: 411 QQLRREQQLRRE-QQLRREQEEERHEQKHEQE---RREQRLKREQEERRDWLKREEETER 466
Query: 106 GAVGPHKRQHPGRREDE--ASWSVDVTQHKRQHPGRRSPWLAYAVPKR--QHPGRRLADP 161
K+Q +E+E W + +R+ RR L +R Q R+ +
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Query: 162 KAQRSWEEEE----EEEEREEDLMPEKRQ 186
+ Q+ E+ E+EER E L+ + +
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEE 555
Score = 32.7 bits (73), Expect = 0.29
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 23 RAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSK 82
R + E Q+E E P + R+ ER RE + Q ++ Q+ + + +
Sbjct: 1081 RKEEELQQEEEQLLREEP---EKRRRQERERQCREEEELQQEEE------QLLREEREKR 1131
Query: 83 RQHPGKREEEEEEGVEEEEE----EEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPG 138
R+ +R+ EEE V++EEE EE + + R E+E + + Q
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Query: 139 RRSPWLAYAVP---KRQHPGRRLADPKAQRS-----WEEEEEEEEREEDLMPEKRQHPGK 190
R+ Y +RQ +R D + QRS WE E+E R+ + + R++
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRD-EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 191 RAL 193
R L
Sbjct: 1251 RQL 1253
Score = 32.7 bits (73), Expect = 0.29
Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 16/150 (10%)
Query: 41 GLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEE 100
G + LR+ ER RE Q+L+ + E Q Q + + + EE+ + E+E
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 101 E---EEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRR 157
+ +E + ++ P R E + + + +R R L +++ ++
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQ------LRRQERDRKFREEEQL-----RQEREEQQ 1787
Query: 158 LADPKAQRSWEEEEE--EEEREEDLMPEKR 185
L ++ R + EEE+ +E E+ L P++R
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Score = 32.0 bits (71), Expect = 0.50
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 60 QRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRR 119
Q+L+ DQ E + + + +R+ +RE++ EE E+ KRQ R
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR------LKRQEEEER 527
Query: 120 EDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREED 179
+ S Q +R+ RR L KR+ R + + QR E+EE ++
Sbjct: 528 LQQRLRSEQ--QLRREQEERREQLL-----KREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 180 LMPEKRQHPGKR 191
E+RQ KR
Sbjct: 581 REEERRQQRLKR 592
Score = 30.4 bits (67), Expect = 1.4
Identities = 30/138 (21%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 60 QRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEE-EEGVEEEEEEEGGA-----VGPHKR 113
QRL+ +Q E + DWL + + + E+E ++ ++ ++EEE +R
Sbjct: 445 QRLKREQEE-------RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 114 QHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEE 173
+ RRE + + + +R L + Q R + + Q EEE+
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 174 EEREEDLMPEKRQHPGKR 191
E+E KR+ +R
Sbjct: 558 LEQERREQRLKREQEERR 575
Score = 28.5 bits (62), Expect = 5.5
Identities = 36/159 (22%), Positives = 60/159 (37%), Gaps = 33/159 (20%)
Query: 43 DDFLRQVERLLFLRENIQRLQGDQG------EHSASQIFQSDWLSKRQHPGKRE------ 90
D R+ E+L RE Q+L+ + E Q + L +Q GK
Sbjct: 1770 DRKFREEEQLRQEREE-QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 91 --EEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAV 148
EE+E+ + +E + + A Q RRE++ W Q + Q
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW-----QEEEQ------------- 1870
Query: 149 PKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQH 187
+RQ R+L + +R +EE+ + E E + H
Sbjct: 1871 KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGH 1909
Score = 28.1 bits (61), Expect = 7.2
Identities = 34/137 (24%), Positives = 60/137 (43%), Gaps = 19/137 (13%)
Query: 46 LRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEG 105
L + ER RE Q+++ + E F + RQ ++ EEE+ ++E EE
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERK----FLEEEQQLRQERHRKFREEEQLLQEREE--- 1475
Query: 106 GAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGR--RSPWLAYAVPKRQ--HPGRRLADP 161
Q R+E + + + Q +RQ R R L P+R+ ++L
Sbjct: 1476 --------QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ 1527
Query: 162 KAQRSWEEEEEEEEREE 178
+ QR + +EE++ R+E
Sbjct: 1528 QRQRKFLQEEQQLRRQE 1544
Score = 27.7 bits (60), Expect = 9.4
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 17/99 (17%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
KR+E+E E E EE+ E Q +R DE W +RQ R
Sbjct: 140 KRQEQERELAEGEEQSE---KQERLEQRDRQRRDEELW------RQRQEWQERE------ 184
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQ 186
+R+ +L K + E +EE+ R +L+ +R+
Sbjct: 185 --ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK 221
Score = 27.7 bits (60), Expect = 9.4
Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 83 RQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSP 142
RQ ++ EEE+ + +E + + Q P R+ E + Q +R+
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Query: 143 WLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQ 186
+RQ G++ + ++ EEE+ +EREE + + +
Sbjct: 1540 L------RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
Length = 1083
Score = 41.6 bits (96), Expect = 6e-04
Identities = 39/139 (28%), Positives = 55/139 (39%), Gaps = 10/139 (7%)
Query: 82 KRQHP-GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPG-- 138
K + P + EEEEEE +EEEEEE P K +H G DEA + + G
Sbjct: 38 KEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAE 97
Query: 139 ---RRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGG 195
++ + V G R + Q W ++ EEE E + + G+ GG
Sbjct: 98 DILEKASNIDNVVLDEDRSGAR----RLQNLWRDQREEELGEYYMKKYAKSSVGETVYGG 153
Query: 196 PCGPQGAYGQAGLLLGLLD 214
Q LL G+ D
Sbjct: 154 SDELSDDITQQQLLPGVKD 172
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 41.2 bits (95), Expect = 8e-04
Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 12/107 (11%)
Query: 86 PGKREEEEEEGVEEEEEEEGGAVGP----HKRQHPGRREDEASWSVDVTQHKRQHPGRRS 141
P EE++E+G E++EEEE GP + + EDE + G
Sbjct: 156 PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEE 215
Query: 142 PWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREED--LMPEKRQ 186
L+Y + + + D + + EE EEEE EE+ L EKR+
Sbjct: 216 VGLSYLMKE------EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 256
Score = 32.7 bits (73), Expect = 0.29
Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 5/49 (10%)
Query: 79 WLSKRQHPGKREEEE--EEGVEEEEEEEGGAVGPHKR---QHPGRREDE 122
+L K + + ++++ EEG EEEEEEEGG G ++ + G ED+
Sbjct: 220 YLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 41.2 bits (95), Expect = 8e-04
Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 12/107 (11%)
Query: 86 PGKREEEEEEGVEEEEEEEGGAVGP----HKRQHPGRREDEASWSVDVTQHKRQHPGRRS 141
P EE++E+G E++EEEE GP + + EDE + G
Sbjct: 115 PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEE 174
Query: 142 PWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREED--LMPEKRQ 186
L+Y + + + D + + EE EEEE EE+ L EKR+
Sbjct: 175 VGLSYLMKE------EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 215
Score = 32.7 bits (73), Expect = 0.29
Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 5/49 (10%)
Query: 79 WLSKRQHPGKREEEE--EEGVEEEEEEEGGAVGPHKR---QHPGRREDE 122
+L K + + ++++ EEG EEEEEEEGG G ++ + G ED+
Sbjct: 179 YLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 41.2 bits (95), Expect = 8e-04
Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 12/107 (11%)
Query: 86 PGKREEEEEEGVEEEEEEEGGAVGP----HKRQHPGRREDEASWSVDVTQHKRQHPGRRS 141
P EE++E+G E++EEEE GP + + EDE + G
Sbjct: 108 PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEE 167
Query: 142 PWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREED--LMPEKRQ 186
L+Y + + + D + + EE EEEE EE+ L EKR+
Sbjct: 168 VGLSYLMKE------EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 208
Score = 32.7 bits (73), Expect = 0.29
Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 5/49 (10%)
Query: 79 WLSKRQHPGKREEEE--EEGVEEEEEEEGGAVGPHKR---QHPGRREDE 122
+L K + + ++++ EEG EEEEEEEGG G ++ + G ED+
Sbjct: 172 YLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 40.8 bits (94), Expect = 0.001
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 25/151 (16%)
Query: 31 QEAVTAAEHPGLDDFLRQVERLLFLRENIQ--RLQGDQGEHSASQIFQSDWLSKRQHPGK 88
+E + ++ L D + V + L N Q L+G Q + S + QS + S RQ K
Sbjct: 1453 KERIRNHKYRSLGDLEKDV---MLLCHNAQTFNLEGSQ-IYEDSIVLQSVFKSARQKIAK 1508
Query: 89 REEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEA-SWSVDVTQHKRQHPGRRSPWLAYA 147
EE E+E EEEEEE+ E EA S V + +K+ GR
Sbjct: 1509 EEESEDESNEEEEEED-----------EEESESEAKSVKVKIKLNKKDDKGRDKG----- 1552
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREE 178
++ P R A P ++ +EE++ERE+
Sbjct: 1553 -KGKKRPNRGKAKPVVS-DFDSDEEQDEREQ 1581
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 40.8 bits (94), Expect = 0.001
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 25/151 (16%)
Query: 31 QEAVTAAEHPGLDDFLRQVERLLFLRENIQ--RLQGDQGEHSASQIFQSDWLSKRQHPGK 88
+E + ++ L D + V + L N Q L+G Q + S + QS + S RQ K
Sbjct: 1435 KERIRNHKYRSLGDLEKDV---MLLCHNAQTFNLEGSQ-IYEDSIVLQSVFKSARQKIAK 1490
Query: 89 REEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEA-SWSVDVTQHKRQHPGRRSPWLAYA 147
EE E+E EEEEEE+ E EA S V + +K+ GR
Sbjct: 1491 EEESEDESNEEEEEED-----------EEESESEAKSVKVKIKLNKKDDKGRDKG----- 1534
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREE 178
++ P R A P ++ +EE++ERE+
Sbjct: 1535 -KGKKRPNRGKAKPVVS-DFDSDEEQDEREQ 1563
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/191 (24%), Positives = 79/191 (41%), Gaps = 41/191 (21%)
Query: 19 VPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSD 78
+PGG+ +P+ +E P +D + V + + + + E+ A + +
Sbjct: 295 LPGGQVEPDLVLEEV-----EPPWEDAHQDVSTS---PQGTEVVPAYEEENKAVEKMPRE 346
Query: 79 WLSKRQHPGKREEEEEEGVEEEEEEE----------GGAVGPHKRQHPGRR----EDEAS 124
LS+ + + EEEEEE EEEEEEE VG + + G R D+
Sbjct: 347 -LSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQSEEDGTRPQSTSDQKL 405
Query: 125 WSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQR---SWEEEEEEEEREEDL- 180
W + K++ A K + +A+ +A++ W E +EE E E +
Sbjct: 406 WEEVGEEAKKE-----------AEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAA 454
Query: 181 ---MPEKRQHP 188
+P +QHP
Sbjct: 455 SSGVPATKQHP 465
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
KREEEE + EE ++ + + + RRE+E ++ + K++ RR A
Sbjct: 743 KREEEERKRQEELRRQQEEILRRQQEEERKRREEE-----ELARRKQEEALRRQREQEIA 797
Query: 148 VPKRQHPGRRLADPKAQRSWEE---EEEEEEREEDLMPEKRQHPGKRA 192
+ +++ R +A R EE EEEE ++E+L+ ++ + K A
Sbjct: 798 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 845
Score = 34.3 bits (77), Expect = 0.10
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 13/166 (7%)
Query: 27 EAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHP 86
EA + E ++ RQ E +L ++ +R + ++ E + + ++ + Q
Sbjct: 737 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEI 796
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAY 146
R + EEE +++EE +R RRE+E + K++ +
Sbjct: 797 ALRRQREEEERQQQEE-------ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 849
Query: 147 AVPKRQHPGRRLADPKAQRSWEEEEE------EEEREEDLMPEKRQ 186
+R R + +A R EEEE E +R+++LM +++Q
Sbjct: 850 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 895
Score = 30.0 bits (66), Expect = 1.9
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 14/107 (13%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
++E E E + EEEE KRQ RR+ E ++ + +++ +R A
Sbjct: 732 EQERREAEMRAKREEEE------RKRQEELRRQQE-----EILRRQQEEERKRREEEELA 780
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREEDL---MPEKRQHPGKR 191
K++ RR + + + EEEE +++E+ + E+R+ +R
Sbjct: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 827
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
KREEEE + EE ++ + + + RRE+E ++ + K++ RR A
Sbjct: 770 KREEEERKRQEELRRQQEEILRRQQEEERKRREEE-----ELARRKQEEALRRQREQEIA 824
Query: 148 VPKRQHPGRRLADPKAQRSWEE---EEEEEEREEDLMPEKRQHPGKRA 192
+ +++ R +A R EE EEEE ++E+L+ ++ + K A
Sbjct: 825 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 872
Score = 34.3 bits (77), Expect = 0.10
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 13/166 (7%)
Query: 27 EAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHP 86
EA + E ++ RQ E +L ++ +R + ++ E + + ++ + Q
Sbjct: 764 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEI 823
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAY 146
R + EEE +++EE +R RRE+E + K++ +
Sbjct: 824 ALRRQREEEERQQQEE-------ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 876
Query: 147 AVPKRQHPGRRLADPKAQRSWEEEEE------EEEREEDLMPEKRQ 186
+R R + +A R EEEE E +R+++LM +++Q
Sbjct: 877 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 922
Score = 30.0 bits (66), Expect = 1.9
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 14/107 (13%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
++E E E + EEEE KRQ RR+ E ++ + +++ +R A
Sbjct: 759 EQERREAEMRAKREEEE------RKRQEELRRQQE-----EILRRQQEEERKRREEEELA 807
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREEDL---MPEKRQHPGKR 191
K++ RR + + + EEEE +++E+ + E+R+ +R
Sbjct: 808 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 854
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
KREEEE + EE ++ + + + RRE+E ++ + K++ RR A
Sbjct: 749 KREEEERKRQEELRRQQEEILRRQQEEERKRREEE-----ELARRKQEEALRRQREQEIA 803
Query: 148 VPKRQHPGRRLADPKAQRSWEE---EEEEEEREEDLMPEKRQHPGKRA 192
+ +++ R +A R EE EEEE ++E+L+ ++ + K A
Sbjct: 804 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851
Score = 34.3 bits (77), Expect = 0.10
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 13/166 (7%)
Query: 27 EAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHP 86
EA + E ++ RQ E +L ++ +R + ++ E + + ++ + Q
Sbjct: 743 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEI 802
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAY 146
R + EEE +++EE +R RRE+E + K++ +
Sbjct: 803 ALRRQREEEERQQQEE-------ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 855
Query: 147 AVPKRQHPGRRLADPKAQRSWEEEEE------EEEREEDLMPEKRQ 186
+R R + +A R EEEE E +R+++LM +++Q
Sbjct: 856 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
Score = 30.0 bits (66), Expect = 1.9
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 14/107 (13%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
++E E E + EEEE KRQ RR+ E ++ + +++ +R A
Sbjct: 738 EQERREAEMRAKREEEE------RKRQEELRRQQE-----EILRRQQEEERKRREEEELA 786
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREEDL---MPEKRQHPGKR 191
K++ RR + + + EEEE +++E+ + E+R+ +R
Sbjct: 787 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
KREEEE + EE ++ + + + RRE+E ++ + K++ RR A
Sbjct: 749 KREEEERKRQEELRRQQEEILRRQQEEERKRREEE-----ELARRKQEEALRRQREQEIA 803
Query: 148 VPKRQHPGRRLADPKAQRSWEE---EEEEEEREEDLMPEKRQHPGKRA 192
+ +++ R +A R EE EEEE ++E+L+ ++ + K A
Sbjct: 804 LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851
Score = 34.3 bits (77), Expect = 0.10
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 13/166 (7%)
Query: 27 EAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHP 86
EA + E ++ RQ E +L ++ +R + ++ E + + ++ + Q
Sbjct: 743 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEI 802
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAY 146
R + EEE +++EE +R RRE+E + K++ +
Sbjct: 803 ALRRQREEEERQQQEE-------ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 855
Query: 147 AVPKRQHPGRRLADPKAQRSWEEEEE------EEEREEDLMPEKRQ 186
+R R + +A R EEEE E +R+++LM +++Q
Sbjct: 856 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
Score = 30.0 bits (66), Expect = 1.9
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 14/107 (13%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
++E E E + EEEE KRQ RR+ E ++ + +++ +R A
Sbjct: 738 EQERREAEMRAKREEEE------RKRQEELRRQQE-----EILRRQQEEERKRREEEELA 786
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREEDL---MPEKRQHPGKR 191
K++ RR + + + EEEE +++E+ + E+R+ +R
Sbjct: 787 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 12/121 (9%)
Query: 60 QRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRR 119
+R+ D + Q + + + EEEEEE EEEEE+E + GRR
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRR 340
Query: 120 EDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREED 179
+ + W D SPW+ + +R+ R +P+ + E E E+
Sbjct: 341 KAKKKWRKD------------SPWVKPSRKRRKREPPRAKEPRGVSNDTSSLETERGFEE 388
Query: 180 L 180
L
Sbjct: 389 L 389
Score = 28.5 bits (62), Expect = 5.5
Identities = 15/46 (32%), Positives = 24/46 (52%)
Query: 157 RLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGA 202
+L++ + + EEEEEEEE EE+ E + + G G + A
Sbjct: 297 QLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKA 342
Score = 27.7 bits (60), Expect = 9.4
Identities = 14/38 (36%), Positives = 19/38 (50%)
Query: 168 EEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQ 205
EEEEEEEE EE+ E+ + G G+ G+
Sbjct: 302 EEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGR 339
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 40.0 bits (92), Expect = 0.002
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 16/144 (11%)
Query: 82 KRQHP-GKREEEEEEGVEEEEEEEGGAVGPHKRQHPG----------RREDEASWSVDVT 130
K + P + EEEEEE +EEEEEE P K +H G EDE W
Sbjct: 38 KEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAE 97
Query: 131 QHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGK 190
+ S + + + RRL Q W ++ EEE E + + G+
Sbjct: 98 DILEKEEIEASNIDNVVLDEDRSGARRL-----QNLWRDQREEELGEYYMKKYAKSSVGE 152
Query: 191 RALGGPCGPQGAYGQAGLLLGLLD 214
GG Q LL G+ D
Sbjct: 153 TVYGGSDELSDDITQQQLLPGVKD 176
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 40.0 bits (92), Expect = 0.002
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 16/144 (11%)
Query: 82 KRQHP-GKREEEEEEGVEEEEEEEGGAVGPHKRQHPG----------RREDEASWSVDVT 130
K + P + EEEEEE +EEEEEE P K +H G EDE W
Sbjct: 38 KEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAE 97
Query: 131 QHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGK 190
+ S + + + RRL Q W ++ EEE E + + G+
Sbjct: 98 DILEKEEIEASNIDNVVLDEDRSGARRL-----QNLWRDQREEELGEYYMKKYAKSSVGE 152
Query: 191 RALGGPCGPQGAYGQAGLLLGLLD 214
GG Q LL G+ D
Sbjct: 153 TVYGGSDELSDDITQQQLLPGVKD 176
>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 40.0 bits (92), Expect = 0.002
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 16/144 (11%)
Query: 82 KRQHP-GKREEEEEEGVEEEEEEEGGAVGPHKRQHPG----------RREDEASWSVDVT 130
K + P + EEEEEE +EEEEEE P K +H G EDE W
Sbjct: 38 KEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAE 97
Query: 131 QHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGK 190
+ S + + + RRL Q W ++ EEE E + + G+
Sbjct: 98 DILEKEEIEASNIDNVVLDEDRSGARRL-----QNLWRDQREEELGEYYMKKYAKSSVGE 152
Query: 191 RALGGPCGPQGAYGQAGLLLGLLD 214
GG Q LL G+ D
Sbjct: 153 TVYGGSDELSDDITQQQLLPGVKD 176
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 39.3 bits (90), Expect = 0.003
Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 7/130 (5%)
Query: 56 RENIQRLQGDQGEHSAS--QIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKR 113
+E +R QG Q E + + + + + G REEEEE+ E +EE EG V +
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGERE 769
Query: 114 QHPGRR--EDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQH---PGRRLADPKAQRSWE 168
+ G R E+ A + Q G K + G + + K +R E
Sbjct: 770 KEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Query: 169 EEEEEEEREE 178
EEE E E EE
Sbjct: 830 EEEGEGEEEE 839
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAY 146
G+ EE E EG EEE EEEG G + + G E+E V+ + G
Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE--EE 1038
Query: 147 AVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQ 186
+ + + + +R+ EEEEEEE + ++ E+ +
Sbjct: 1039 GEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENE 1078
Score = 33.9 bits (76), Expect = 0.13
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 12/92 (13%)
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAY 146
G+ EEEE EG EE+EE G G + G RE+E + G
Sbjct: 794 GEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE------------EEEGEGEEEEGE 841
Query: 147 AVPKRQHPGRRLADPKAQRSWEEEEEEEEREE 178
+ + K + EE E EEE EE
Sbjct: 842 GEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Score = 33.5 bits (75), Expect = 0.17
Identities = 40/160 (25%), Positives = 60/160 (37%), Gaps = 17/160 (10%)
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKR-QHPGRREDEASWSVDVTQHKRQHPGRRSPWLA 145
GK EEE EEG EEE EEG G + + G E E + + + + G
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915
Query: 146 YAVPKRQHPGRRLADPKAQRSWEEEE---EEEEREEDLMPEKRQHPGKRALGGPCGPQGA 202
K + G + + EEEE E E+ E + E+ + G+ G G +
Sbjct: 916 EGEGKGEEEGE-----EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEG 970
Query: 203 YGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPLEE 242
G+ + +G EE+ + G E EE
Sbjct: 971 EGEG--------EEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Score = 32.7 bits (73), Expect = 0.29
Identities = 38/169 (22%), Positives = 70/169 (41%), Gaps = 12/169 (7%)
Query: 63 QGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDE 122
+G++ + + + + + G+ EEEE EG EEE EEG G + + G ED
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG-EEEEGEGEGEDG 944
Query: 123 ASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMP 182
+ + + + G + + G + + EEEE E E EE+
Sbjct: 945 EG---EGEEEEGEWEGEEEEGEGEGEEEGEGEGE-----EGEGEGEEEEGEGEGEEEEGE 996
Query: 183 EKRQHPGKRALGGPCGPQGAYGQAGLLLGLLD-DLSRSQGAEEKRQHPG 230
E+ + G+ G +G + G + G ++ + +G EE+ + G
Sbjct: 997 EEGEEEGEGEEEGE--GEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG 1043
Score = 32.3 bits (72), Expect = 0.38
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 92 EEEEGVEEE-----EEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGR-RSPWLA 145
EE+EG E+ EE+E A + + H GR+E S D+T G+ +S A
Sbjct: 588 EEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEA 647
Query: 146 YAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGK 190
P+ + G W ++EE E+ E+D + + PG+
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHW-QDEEREKGEKDKGRGEMERPGE 691
Score = 31.6 bits (70), Expect = 0.65
Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 7/101 (6%)
Query: 82 KRQHPGKREEEEEEGVEEE---EEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPG 138
+ + G+ EEEE EG EEE EEEEG G + + E+ + + + + G
Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887
Query: 139 RRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREED 179
+ G + + + EEEE E + EE+
Sbjct: 888 EEEG----EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEE 924
Score = 29.6 bits (65), Expect = 2.5
Identities = 27/114 (23%), Positives = 42/114 (36%), Gaps = 1/114 (0%)
Query: 65 DQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEAS 124
++GE + + + G+ E EEEEG E EEE G + + G E E
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE 911
Query: 125 WSVDVTQHKRQHPGRRSPWLAYAVP-KRQHPGRRLADPKAQRSWEEEEEEEERE 177
+ + K + G + + + + WE EEEE E E
Sbjct: 912 GEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965
Score = 28.9 bits (63), Expect = 4.2
Identities = 30/142 (21%), Positives = 62/142 (43%), Gaps = 16/142 (11%)
Query: 57 ENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEE---EEGVEEEEEEEGGA--VGPH 111
E + + +G Q +++ + + H G++E+ E ++ ++ E EG A VG
Sbjct: 588 EEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEA 647
Query: 112 KRQHPGRRE---DEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWE 168
+ GR + +E S + Q + + G + + + PG + + W+
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRG----EMERPGEGEKELAEKEEWK 703
Query: 169 ----EEEEEEEREEDLMPEKRQ 186
EE+E++ERE+ E+ Q
Sbjct: 704 KRDGEEQEQKEREQGHQKERNQ 725
Score = 28.5 bits (62), Expect = 5.5
Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 4/96 (4%)
Query: 84 QHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPW 143
+ G+ EEEE EG EEE EEG + G E E + + + G
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEG---EEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 900
Query: 144 LAYAVPKRQHPG-RRLADPKAQRSWEEEEEEEEREE 178
+ + G + K + EE E E E EE
Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936
Score = 28.5 bits (62), Expect = 5.5
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 17/66 (25%)
Query: 62 LQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVE-----EEEEEEGGAVGPHKRQHP 116
++G++GE + + + G+ E+E EG E EEEEEE G K Q
Sbjct: 1025 VEGEEGEGEGEE-------EEGEEEGEEREKEGEGEENRRNREEEEEEEG-----KYQET 1072
Query: 117 GRREDE 122
G E+E
Sbjct: 1073 GEEENE 1078
>gi|55749431 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 39.3 bits (90), Expect = 0.003
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 19/161 (11%)
Query: 65 DQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEAS 124
D+G+ + + D K + GKRE+E E G E + E+EG + + G+ + E
Sbjct: 26 DEGKSDEEE--KPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83
Query: 125 WSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPE- 183
+ + + P Y K + R D + S E+ +E E++M E
Sbjct: 84 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMREC 143
Query: 184 -----------KRQHPG-----KRALGGPCGPQGAYGQAGL 208
K+Q G +R + P P+G G G+
Sbjct: 144 GDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGV 184
Score = 29.6 bits (65), Expect = 2.5
Identities = 39/158 (24%), Positives = 62/158 (39%), Gaps = 39/158 (24%)
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKR-QHPGRRSPW-- 143
GK +EEE+ VE + E EG KR+ G DE + +Q K+ + G P
Sbjct: 28 GKSDEEEKPDVEGKTECEG------KREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGE 81
Query: 144 ---LAYAVPKRQ------HPGRRLADPKAQRSWEE--EEEEEEREEDLMPEKRQHPGKRA 192
+ A P+ Q P KA+R + ++ ++ +EDL + +H
Sbjct: 82 GKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDL---QERHLSSEE 138
Query: 193 LGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPG 230
+ CG D+SR+Q K+Q G
Sbjct: 139 MMRECG----------------DVSRAQEELRKKQKMG 160
>gi|14249718 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 39.3 bits (90), Expect = 0.003
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 19/161 (11%)
Query: 65 DQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEAS 124
D+G+ + + D K + GKRE+E E G E + E+EG + + G+ + E
Sbjct: 26 DEGKSDEEE--KPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83
Query: 125 WSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPE- 183
+ + + P Y K + R D + S E+ +E E++M E
Sbjct: 84 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMREC 143
Query: 184 -----------KRQHPG-----KRALGGPCGPQGAYGQAGL 208
K+Q G +R + P P+G G G+
Sbjct: 144 GDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGV 184
Score = 29.6 bits (65), Expect = 2.5
Identities = 39/158 (24%), Positives = 62/158 (39%), Gaps = 39/158 (24%)
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKR-QHPGRRSPW-- 143
GK +EEE+ VE + E EG KR+ G DE + +Q K+ + G P
Sbjct: 28 GKSDEEEKPDVEGKTECEG------KREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGE 81
Query: 144 ---LAYAVPKRQ------HPGRRLADPKAQRSWEE--EEEEEEREEDLMPEKRQHPGKRA 192
+ A P+ Q P KA+R + ++ ++ +EDL + +H
Sbjct: 82 GKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDL---QERHLSSEE 138
Query: 193 LGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPG 230
+ CG D+SR+Q K+Q G
Sbjct: 139 MMRECG----------------DVSRAQEELRKKQKMG 160
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 38.9 bits (89), Expect = 0.004
Identities = 47/190 (24%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 1 MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQ 60
+PGP L L G PGG P A +E +T D+ + E +
Sbjct: 849 VPGPVTLPPPQLVPE--GTPGGGGPP--ALEEDLTVININSSDEEEEEEE---------E 895
Query: 61 RLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRRE 120
+ ++ E + F+ + + ++ + EEEEEE EEE EEE G + + + E
Sbjct: 896 EEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE-FEEEFEEEEGELEEEEEEEDEEEE 954
Query: 121 DEASWSVDV----TQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSW----EEEEE 172
+E D+ + + P L A+P + P + +P+ + EE
Sbjct: 955 EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014
Query: 173 EEEREEDLMP 182
EEER D P
Sbjct: 1015 EEERGADTAP 1024
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.9 bits (89), Expect = 0.004
Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 11/115 (9%)
Query: 8 LALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQG 67
L A+ + GVP P + E E GLDD+ + E ++++G++
Sbjct: 469 LCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDW-----EAMASDEETEKVEGNKV 523
Query: 68 EHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDE 122
+ + + + EEEE+E EEEEEEEG + G + + DE
Sbjct: 524 HIEVKEN------PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDE 572
Score = 33.5 bits (75), Expect = 0.17
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 15/99 (15%)
Query: 88 KREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYA 147
K+++++++ E+EE+E+ GP K +E A + + KR+ R
Sbjct: 314 KKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERI------- 366
Query: 148 VPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQ 186
+RL + +A+R EE E+E+RE EK +
Sbjct: 367 --------KRLEELEAKRKEEERLEQEKRERKKQKEKER 397
Score = 29.6 bits (65), Expect = 2.5
Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 90 EEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGR---RSPWLAY 146
EE+ E E++ EG K++ G +E++ + K++ P + ++ A
Sbjct: 296 EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEK-------EKEKKKGPSKATVKAMQEAL 348
Query: 147 AVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQ 186
A K + ++ + + + EE E + + EE L EKR+
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRE 388
>gi|61175239 transcription elongation factor A (SII)-like 5 [Homo
sapiens]
Length = 206
Score = 38.9 bits (89), Expect = 0.004
Identities = 37/161 (22%), Positives = 62/161 (38%), Gaps = 19/161 (11%)
Query: 65 DQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEAS 124
D+G+ + + D K + GKRE+E E G E + E+EG K + + + E
Sbjct: 32 DEGKSDEEE--KPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGK 89
Query: 125 WSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPE- 183
+ + + P Y K + R D + S E+ +E E++M E
Sbjct: 90 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMREC 149
Query: 184 -----------KRQHPG-----KRALGGPCGPQGAYGQAGL 208
K+Q G +R + P P+G G G+
Sbjct: 150 GDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGV 190
Score = 29.6 bits (65), Expect = 2.5
Identities = 40/164 (24%), Positives = 62/164 (37%), Gaps = 39/164 (23%)
Query: 87 GKREEE---EEEGVEEEEEE---EGGAVGPHKRQHPGRREDEASWSVDVTQHKR------ 134
GK E+E E+EG +EEE+ EG KR+ G DE + Q K+
Sbjct: 22 GKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGE 81
Query: 135 QHPGRRSPWLAYAVPKRQ------HPGRRLADPKAQRSWEE--EEEEEEREEDLMPEKRQ 186
P + A P+ Q P KA+R + ++ ++ +EDL + +
Sbjct: 82 DKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDL---QER 138
Query: 187 HPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPG 230
H + CG D+SR+Q K+Q G
Sbjct: 139 HLSSEEMMRECG----------------DVSRAQEELRKKQKMG 166
Score = 28.1 bits (61), Expect = 7.2
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 161 PKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQ 220
P+ + S E+E + +E E+ M K + GKR G G +G G + +S+
Sbjct: 24 PEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDE----GNQEKQGKSE 79
Query: 221 GAEEKRQHPGRRAA 234
G E+K Q G+ A+
Sbjct: 80 G-EDKPQSEGKPAS 92
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 10/110 (9%)
Query: 80 LSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGR 139
+S+ Q + E++E E E EEEE+ A H ED+ + + P R
Sbjct: 1279 VSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR 1338
Query: 140 RSPWLAYAVPKRQHPG--RRLADPKAQRSWEEEEEEEEREEDLMPEKRQH 187
++ PG D Q+S E+ +++EE E D E+ H
Sbjct: 1339 ED--------VKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
Score = 32.7 bits (73), Expect = 0.29
Identities = 33/107 (30%), Positives = 40/107 (37%), Gaps = 20/107 (18%)
Query: 86 PGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLA 145
P +R+EEEE E EE EE G ED AS V SP
Sbjct: 1220 PEERKEEEEMQAEAEEAEE------------GEEEDAASSEVPAAS---PADSSNSPETE 1264
Query: 146 YAVPKRQHPGRRLADPKAQRSWEE-----EEEEEEREEDLMPEKRQH 187
P+ + + + QR EE EE E E EED E Q+
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 10/110 (9%)
Query: 80 LSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGR 139
+S+ Q + E++E E E EEEE+ A H ED+ + + P R
Sbjct: 1279 VSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR 1338
Query: 140 RSPWLAYAVPKRQHPG--RRLADPKAQRSWEEEEEEEEREEDLMPEKRQH 187
++ PG D Q+S E+ +++EE E D E+ H
Sbjct: 1339 ED--------VKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
Score = 32.7 bits (73), Expect = 0.29
Identities = 33/107 (30%), Positives = 40/107 (37%), Gaps = 20/107 (18%)
Query: 86 PGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLA 145
P +R+EEEE E EE EE G ED AS V SP
Sbjct: 1220 PEERKEEEEMQAEAEEAEE------------GEEEDAASSEVPAAS---PADSSNSPETE 1264
Query: 146 YAVPKRQHPGRRLADPKAQRSWEE-----EEEEEEREEDLMPEKRQH 187
P+ + + + QR EE EE E E EED E Q+
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 10/110 (9%)
Query: 80 LSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGR 139
+S+ Q + E++E E E EEEE+ A H ED+ + + P R
Sbjct: 1279 VSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR 1338
Query: 140 RSPWLAYAVPKRQHPG--RRLADPKAQRSWEEEEEEEEREEDLMPEKRQH 187
++ PG D Q+S E+ +++EE E D E+ H
Sbjct: 1339 ED--------VKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
Score = 32.7 bits (73), Expect = 0.29
Identities = 33/107 (30%), Positives = 40/107 (37%), Gaps = 20/107 (18%)
Query: 86 PGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLA 145
P +R+EEEE E EE EE G ED AS V SP
Sbjct: 1220 PEERKEEEEMQAEAEEAEE------------GEEEDAASSEVPAAS---PADSSNSPETE 1264
Query: 146 YAVPKRQHPGRRLADPKAQRSWEE-----EEEEEEREEDLMPEKRQH 187
P+ + + + QR EE EE E E EED E Q+
Sbjct: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
>gi|157694505 LINE-1 type transposase domain containing 1 [Homo
sapiens]
Length = 865
Score = 38.5 bits (88), Expect = 0.005
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
Query: 87 GKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAY 146
G ++E+ G+EEEEEE G + + G EDEAS + + + Q + S + +
Sbjct: 393 GMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEAS---GLEEEEEQTSEQDSTFQGH 449
Query: 147 AVPKRQHPGRRLADPKAQR---SWEEEEEEEERE 177
+ +H +D S E+ E EEE E
Sbjct: 450 TLVDAKHEVEITSDGMETTFIDSVEDSESEEEEE 483
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 38.5 bits (88), Expect = 0.005
Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
Query: 90 EEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVP 149
E +E+ VEE++E G P P R E+E + + + ++ RR A P
Sbjct: 1282 EPDEQVTVEEQKETSEGKTSPS----PIRIEEEVKETGEALLPQEEN--RREETCAPVSP 1335
Query: 150 KRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPG 189
PG + D + EEEEEEEE EE+ E + G
Sbjct: 1336 NTS-PGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEG 1374
Score = 37.0 bits (84), Expect = 0.015
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 20/94 (21%)
Query: 86 PGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLA 145
P + EEEEEE EEEEEEEG E+E +V+ + + P
Sbjct: 1350 PEEEEEEEEEEEEEEEEEEG-------------EEEEGGGNVEKDPDGAKSQEKEEP--- 1393
Query: 146 YAVPKRQHPGRRLADPKAQRSWEEEEEEEEREED 179
+ + RL D + + EEE+EE ED
Sbjct: 1394 -EISTEKEDSARLDDHEEE---EEEDEEPSHNED 1423
Score = 33.5 bits (75), Expect = 0.17
Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 2/109 (1%)
Query: 80 LSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGR 139
LSK + EEE+EE EEEEEEE + + E+ S +T+ + R
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKR 1123
Query: 140 RSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHP 188
+ P++ KR RR+ + E E D E+R P
Sbjct: 1124 KRPFV--LKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMP 1170
Score = 30.0 bits (66), Expect = 1.9
Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 9/120 (7%)
Query: 80 LSKRQHPGKREEE---EEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQH 136
+S+ + ++E E E+ E+EE+E + + RQ P + + + + + R
Sbjct: 997 VSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLH--SPESRPV 1054
Query: 137 PGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGP 196
G R L + + + + + EEEEEEEE EE+ E+ + + P
Sbjct: 1055 TGERGQLLELSKESSEEE----EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110
Score = 30.0 bits (66), Expect = 1.9
Identities = 29/114 (25%), Positives = 43/114 (37%), Gaps = 16/114 (14%)
Query: 67 GEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEE-----EEEEGGAVGPHKRQHPGRRED 121
GE + + + + + + EEEEEEG EEE E++ GA K + E
Sbjct: 1340 GEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEK 1399
Query: 122 EASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEE 175
E S +D H+ + P H AD + E E E+E
Sbjct: 1400 EDSARLD--DHEEEEEEDEEP---------SHNEDHDADDEDDSHMESAEVEKE 1442
Score = 29.3 bits (64), Expect = 3.2
Identities = 15/37 (40%), Positives = 21/37 (56%)
Query: 68 EHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEE 104
E S + + D + + + E+EEEE EEEEEEE
Sbjct: 1067 ESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
Score = 28.1 bits (61), Expect = 7.2
Identities = 15/41 (36%), Positives = 23/41 (56%)
Query: 64 GDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEE 104
G++G+ S+ + + + EEEEEE +EEEEEE
Sbjct: 1056 GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEE 1096
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 38.1 bits (87), Expect = 0.007
Identities = 38/162 (23%), Positives = 67/162 (41%), Gaps = 17/162 (10%)
Query: 47 RQVERLLFLRENIQRLQGDQGEHSASQ----IFQSDWLSKRQHPGKREEEEEEGVEEEEE 102
R E++L RE +R + + E + + + + + +++ + E EE E EEE
Sbjct: 817 RAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEER 876
Query: 103 EEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPK 162
G + K G R+ E +W R+ P S W K G + +
Sbjct: 877 RLGDSSLSRKDSRWGDRDSEGTW--------RKGPEADSEWRRGPPEKEWRRGEGRDEDR 928
Query: 163 AQRSWEEEE----EEEEREEDLMPEKRQHPGKRALGGPCGPQ 200
+ R EE ++E+RE L P+ + P +R + GP+
Sbjct: 929 SHRRDEERPRRLGDDEDREPSLRPDDDRVP-RRGMDDDRGPR 969
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,098,532
Number of Sequences: 37866
Number of extensions: 776345
Number of successful extensions: 18022
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 346
Number of HSP's successfully gapped in prelim test: 474
Number of HSP's that attempted gapping in prelim test: 8482
Number of HSP's gapped (non-prelim): 5538
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.