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Search of human proteins with 58533170
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
(723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s... 1584 0.0
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho... 1578 0.0
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 627 e-180
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s... 623 e-178
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s... 617 e-176
gi|4505881 plasminogen [Homo sapiens] 462 e-130
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 442 e-124
gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo s... 427 e-119
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 180 5e-45
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 180 5e-45
gi|4504383 HGF activator preproprotein [Homo sapiens] 160 3e-39
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 156 7e-38
gi|145275213 coagulation factor XII precursor [Homo sapiens] 142 1e-33
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 139 9e-33
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi... 137 3e-32
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 137 3e-32
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 128 2e-29
gi|223942069 enterokinase precursor [Homo sapiens] 127 5e-29
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 126 8e-29
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 125 2e-28
gi|4506153 prostasin preproprotein [Homo sapiens] 124 2e-28
gi|33695155 hepsin [Homo sapiens] 122 1e-27
gi|4504481 hepsin [Homo sapiens] 122 1e-27
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 121 3e-27
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 121 3e-27
gi|11496281 kallikrein 13 precursor [Homo sapiens] 120 4e-27
gi|117956391 protease, serine, 33 [Homo sapiens] 119 8e-27
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 119 1e-26
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 119 1e-26
gi|13994276 marapsin [Homo sapiens] 117 5e-26
>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
Length = 723
Score = 1584 bits (4101), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
Query: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF
Sbjct: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
Query: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTEC 300
LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTEC
Sbjct: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTEC 300
Query: 301 IQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWC 360
IQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWC
Sbjct: 301 IQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWC 360
Query: 361 FTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRH 420
FTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRH
Sbjct: 361 FTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRH 420
Query: 421 IFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVI 480
IFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVI
Sbjct: 421 IFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVI 480
Query: 481 SCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYE 540
SCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYE
Sbjct: 481 SCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYE 540
Query: 541 AWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCT 600
AWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCT
Sbjct: 541 AWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCT 600
Query: 601 IPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIG 660
IPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIG
Sbjct: 601 IPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIG 660
Query: 661 SGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKV 720
SGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKV
Sbjct: 661 SGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKV 720
Query: 721 PQS 723
PQS
Sbjct: 721 PQS 723
>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
sapiens]
Length = 728
Score = 1578 bits (4085), Expect = 0.0
Identities = 723/728 (99%), Positives = 723/728 (99%), Gaps = 5/728 (0%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNP 175
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS YRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 235
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
Query: 236 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL 295
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL
Sbjct: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL 300
Query: 296 ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS 355
ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS
Sbjct: 301 ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS 360
Query: 356 ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME 415
ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME
Sbjct: 361 ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME 420
Query: 416 DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL 475
DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL
Sbjct: 421 DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL 480
Query: 476 DHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD 535
DHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD
Sbjct: 481 DHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD 540
Query: 536 LKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLP 595
LKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLP
Sbjct: 541 LKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLP 600
Query: 596 NYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG 655
NYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG
Sbjct: 601 NYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG 660
Query: 656 AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII
Sbjct: 661 AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 720
Query: 716 LTYKVPQS 723
LTYKVPQS
Sbjct: 721 LTYKVPQS 728
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 627 bits (1618), Expect = e-180
Identities = 317/733 (43%), Positives = 421/733 (57%), Gaps = 34/733 (4%)
Query: 2 WVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIKT 61
WVT PA + + L LLL G +R+ +++F+ T L + A+
Sbjct: 5 WVTVQPPARRMGWLPLLLLLTQCL-----GVPGQRSPLNDFQVLRGTELQHLLHAVVPGP 59
Query: 62 KKVNTAD--QCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLY 119
+ + AD +CA RC G C+AF ++ + C P+ S + DL+
Sbjct: 60 WQEDVADAEECAGRC----GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLF 115
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRG---KDLQENYCRNPR 176
+ KDY+R CI+ G Y+GT++ T G+ CQ WS P++H Y L+EN+CRNP
Sbjct: 116 QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNGLEENFCRNPD 175
Query: 177 GEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPH 236
G+ GGPWC+T++P VR++ C I C E C+ CNGE YRG +D TESG+ CQRWD Q PH
Sbjct: 176 GDPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPH 235
Query: 237 RHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPLE 296
+H F P ++ D+G DDNYCRNPDG RPWCYT DP E+C + C +
Sbjct: 236 QHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEA--T 293
Query: 297 TTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSE 356
T C +G+GEGYRGT NT G+PCQRWD+Q PH+H TPE + CKDLREN+CRNPDGSE
Sbjct: 294 TVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSE 353
Query: 357 SPWCFTTDPNIRVGYCSQIPNC-DMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME 415
+PWCFT P +R +C QI C D QDCY G G+ Y G +S+TR G+ C W
Sbjct: 354 APWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETP 413
Query: 416 DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL 475
+ F ++L EN+CRNPD D+HGPWCYT +P P+DYC + RC D P+I++
Sbjct: 414 HKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDP 473
Query: 476 DHPV--ISCAK--------TKQLRVVNGIPTRTNIGWMVSLRYR-NKHICGGSLIKESWV 524
V C K +LRVV G P N W VSLR R +H CGGSL+KE W+
Sbjct: 474 PDQVQFEKCGKRVDRLDQRRSKLRVVGGHP--GNSPWTVSLRNRQGQHFCGGSLVKEQWI 531
Query: 525 LTARQCFPS--RDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARP 582
LTARQCF S L YE WLG + + E Q + V+++V GP GS LVL+KL R
Sbjct: 532 LTARQCFSSCHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERS 591
Query: 583 AVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHR 642
L+ V+ I LP +P T C + GWG T D +L VA L ++ N++C+ HR
Sbjct: 592 VTLNQRVALICLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHR 651
Query: 643 GKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFV 702
G+V ESE+C G CEGDYGGPL C H ++ G+I+P R CA P +F
Sbjct: 652 GRV--RESEMCTEGLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFT 709
Query: 703 RVAYYAKWIHKII 715
RV+ + WIHK++
Sbjct: 710 RVSVFVDWIHKVM 722
>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
sapiens]
Length = 285
Score = 623 bits (1607), Expect = e-178
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
Query: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF
Sbjct: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
Query: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC
Sbjct: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
Score = 152 bits (383), Expect = 1e-36
Identities = 72/175 (41%), Positives = 93/175 (53%), Gaps = 19/175 (10%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR-P 264
C+ G SY+G + T+SG CQ W PH H Y K +NYCRNP G+ P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNPRGEEGGP 182
Query: 265 WCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRW 324
WC+T +P R+E C I C++ EC+ GE YRG ++ +G CQRW
Sbjct: 183 WCFTSNPEVRYEVCDIPQCSE------------VECMTCNGESYRGLMDHTESGKICQRW 230
Query: 325 DSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD 379
D Q PH H PE + K +NYCRNPDG PWC+T DP+ R YC+ I C+
Sbjct: 231 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCA-IKTCE 284
Score = 150 bits (378), Expect = 5e-36
Identities = 77/170 (45%), Positives = 96/170 (56%), Gaps = 17/170 (10%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSES-P 358
CI G+G Y+GTV+ +GI CQ W S PHEH +++ KDL+ENYCRNP G E P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEEGGP 182
Query: 359 WCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH 418
WCFT++P +R C IP C +C NG++Y G + T SG C WD H
Sbjct: 183 WCFTSNPEVRYEVCD-IPQCSEV---ECMTCNGESYRGLMDHTESGKICQRWDHQTP--H 236
Query: 419 RHIFWE---PDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCE 465
RH F PD ++NYCRNPD PWCYT +P W+YC I CE
Sbjct: 237 RHKFLPERYPDKG-FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCE 284
Score = 74.3 bits (181), Expect = 4e-13
Identities = 32/81 (39%), Positives = 47/81 (58%), Gaps = 5/81 (6%)
Query: 384 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 443
++C G G++Y G +S T+SG+ C W + H H + D L ENYCRNP +
Sbjct: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP--HEHSYRGKD---LQENYCRNPRGEEG 180
Query: 444 GPWCYTGNPLIPWDYCPISRC 464
GPWC+T NP + ++ C I +C
Sbjct: 181 GPWCFTSNPEVRYEVCDIPQC 201
>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
sapiens]
Length = 290
Score = 617 bits (1591), Expect = e-176
Identities = 283/288 (98%), Positives = 283/288 (98%), Gaps = 5/288 (1%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 235
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
Query: 236 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC
Sbjct: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
Score = 164 bits (415), Expect = 3e-40
Identities = 75/175 (42%), Positives = 96/175 (54%), Gaps = 14/175 (8%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR-P 264
C+ G SY+G + T+SG CQ W PH H FLP Y K +NYCRNP G+ P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 265 WCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRW 324
WC+T +P R+E C I C++ EC+ GE YRG ++ +G CQRW
Sbjct: 188 WCFTSNPEVRYEVCDIPQCSE------------VECMTCNGESYRGLMDHTESGKICQRW 235
Query: 325 DSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD 379
D Q PH H PE + K +NYCRNPDG PWC+T DP+ R YC+ I C+
Sbjct: 236 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCA-IKTCE 289
Score = 158 bits (400), Expect = 1e-38
Identities = 78/170 (45%), Positives = 97/170 (57%), Gaps = 12/170 (7%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSES-P 358
CI G+G Y+GTV+ +GI CQ W S PHEH P +++ KDL+ENYCRNP G E P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 359 WCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH 418
WCFT++P +R C IP C +C NG++Y G + T SG C WD H
Sbjct: 188 WCFTSNPEVRYEVCD-IPQCSEV---ECMTCNGESYRGLMDHTESGKICQRWDHQTP--H 241
Query: 419 RHIFWE---PDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCE 465
RH F PD ++NYCRNPD PWCYT +P W+YC I CE
Sbjct: 242 RHKFLPERYPDKG-FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCE 289
Score = 74.7 bits (182), Expect = 3e-13
Identities = 30/81 (37%), Positives = 45/81 (55%)
Query: 384 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 443
++C G G++Y G +S T+SG+ C W + H + L ENYCRNP +
Sbjct: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
Query: 444 GPWCYTGNPLIPWDYCPISRC 464
GPWC+T NP + ++ C I +C
Sbjct: 186 GPWCFTSNPEVRYEVCDIPQC 206
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 462 bits (1190), Expect = e-130
Identities = 247/633 (39%), Positives = 337/633 (53%), Gaps = 55/633 (8%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSY-----RGKDLQENYCRNPRGEEGGP 182
C+ G +Y G +S T SG++CQ W S PH H Y K+L++NYCRNP E P
Sbjct: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243
Query: 183 WCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTESGKICQRWDHQT 234
WCFT++P R+E+CDIP+C+ +C+ GE+YRG + T SG CQ W QT
Sbjct: 244 WCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQT 303
Query: 235 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDV- 293
PH H PE +P K D+NYCRNPDG+ PWC+T + RWEYC I +C + ++ +
Sbjct: 304 PHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLA 363
Query: 294 ---PLETT----ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRE 346
P E T +C G G+ YRGT +T G CQ W S PH H TPEN+ L
Sbjct: 364 PTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTM 423
Query: 347 NYCRNPDGSESPWCFTTDPNIRVGYCSQ------------------IPNCDMSHGQDCYR 388
NYCRNPD + PWCFTTDP++R YC+ +P+ + +DC
Sbjct: 424 NYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMF 483
Query: 389 GNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASK---LNENYCRNPDDDAHGP 445
GNGK Y G + T +G C W ++ HRH + P+ + L +NYCRNPD D GP
Sbjct: 484 GNGKGYRGKRATTVTGTPCQDWAA--QEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGP 541
Query: 446 WCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIG-WMV 504
WCYT NP +DYC + +C + + P + K RVV G + W V
Sbjct: 542 WCYTTNPRKLYDYCDVPQCAAPS----FDCGKPQVEPKKCPG-RVVGGCVAHPHSWPWQV 596
Query: 505 SLRYR-NKHICGGSLIKESWVLTARQCFP-SRDLKDYEAWLGIHDVHGRGDEKCKQVLNV 562
SLR R H CGG+LI WVLTA C S Y+ LG H E Q + V
Sbjct: 597 SLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNL--EPHVQEIEV 654
Query: 563 SQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDG 622
S+L P D+ L+KL+ PAV+ D V LP+ + ++T C + GWG T G
Sbjct: 655 SRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAG 714
Query: 623 LLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMV 682
LL+ A L ++ N+ C+++ + +E+CAG G+ C+GD GGPLVC + ++
Sbjct: 715 LLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYIL 774
Query: 683 LGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
GV G GCA PN+PG++VRV+ + WI ++
Sbjct: 775 QGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
Score = 385 bits (989), Expect = e-107
Identities = 185/431 (42%), Positives = 251/431 (58%), Gaps = 36/431 (8%)
Query: 61 TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
TKK + ++CA +C ++ FTC+AF + +QC+ N SS + + +
Sbjct: 37 TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92
Query: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR-----GKDLQENYC 172
L+E K Y+ C G G++Y+GT+S TK+GI CQ WSS PH + + L+ENYC
Sbjct: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
Query: 173 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDH 232
RNP + GPWC+T++PE RY+ CDI +C E ECM C+GE+Y G + T SG CQ WD
Sbjct: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE-ECMHCSGENYDGKISKTMSGLECQAWDS 211
Query: 233 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTD 292
Q+PH H ++P ++P+K NYCRNPD + RPWC+T DP+ RWE C I C T +
Sbjct: 212 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRC--TTPPPSS 269
Query: 293 VPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNP 352
P T +C++G GE YRG V +G CQ W +Q PH H+ TPENF CK+L ENYCRNP
Sbjct: 270 GP--TYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNP 327
Query: 353 DGSESPWCFTTDPNIRVGYCSQIPNCDMSH-----------------GQDCYRGNGKNYM 395
DG +PWC TT+ +R YC +IP+CD S QDCY G+G++Y
Sbjct: 328 DGKRAPWCHTTNSQVRWEYC-KIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYR 386
Query: 396 GNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIP 455
G S T +G C W H+ + L NYCRNPD D GPWC+T +P +
Sbjct: 387 GTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDAD-KGPWCFTTDPSVR 445
Query: 456 WDYCPISRCEG 466
W+YC + +C G
Sbjct: 446 WEYCNLKKCSG 456
Score = 97.1 bits (240), Expect = 5e-20
Identities = 47/129 (36%), Positives = 67/129 (51%), Gaps = 21/129 (16%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKD------LQENYCRNPRGEEG 180
+C+ G G+ Y+G + T +G CQ W++ PH HS + L++NYCRNP G+ G
Sbjct: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539
Query: 181 GPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRWD 231
GPWC+T+NP Y+ CD+PQC+ +VE C G G + H S W
Sbjct: 540 GPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHS------WP 593
Query: 232 HQTPHRHKF 240
Q R +F
Sbjct: 594 WQVSLRTRF 602
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 442 bits (1136), Expect = e-124
Identities = 251/672 (37%), Positives = 326/672 (48%), Gaps = 98/672 (14%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
EN +++C G G+SY+GT+S T +G CQ WSSM PH H Y L NYCRN
Sbjct: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P E PWC+T +P VR+E C++ +C E
Sbjct: 1440 PDAEIR-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPV 1498
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C +G SYRG+ T +G+ CQ W PH H+ PE YP+ G +NYCRNPD
Sbjct: 1499 VQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGK 1558
Query: 263 RPWCYTLDPHTRWEYCAIKTCADNTM----NDTDVPLETTE----------------CIQ 302
+PWCYT DP RWEYC + C++ T VP+ + E C
Sbjct: 1559 QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYH 1618
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ YRGT +T G CQ W S PH H TPEN+ L NYCRNPD PWCFT
Sbjct: 1619 GNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFT 1678
Query: 363 TDPNIRVGYCS------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQTRSG 404
DP+IR YC+ Q+P+ QDC GNGK Y G + T +G
Sbjct: 1679 MDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTG 1738
Query: 405 LTCSMWDKNMEDLHRHIFWEPDASK---LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPI 461
C W ++ HRH + P +K L +NYCRNPD D +GPWCYT NP +DYC I
Sbjct: 1739 TPCQEW--AAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDI 1796
Query: 462 SRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYR-NKHICGGSLIK 520
C + + P + K V + + W VSLR R KH CGG+LI
Sbjct: 1797 PLCASSS----FDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLIS 1852
Query: 521 ESWVLTARQCF-PSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKL 579
WVLTA C S Y+ LG H E Q + VS+L P +D+ L+KL
Sbjct: 1853 PEWVLTAAHCLKKSSRPSSYKVILGAHQEVNL--ESHVQEIEVSRLFLEPTQADIALLKL 1910
Query: 580 ARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQ 639
+RPAV+ D V LP+ + +T C + GWG T GLL+ A L ++ NE C+
Sbjct: 1911 SRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNH 1970
Query: 640 HHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPG 699
+ ICA G+ C+GD GGPLVC + ++ GV G GCA PN+PG
Sbjct: 1971 Y---------KYICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPG 2021
Query: 700 IFVRVAYYAKWI 711
++ RV+ + WI
Sbjct: 2022 VYARVSRFVTWI 2033
Score = 311 bits (796), Expect = 2e-84
Identities = 160/436 (36%), Positives = 208/436 (47%), Gaps = 84/436 (19%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT IT +G CQ WSSM PH HS Y L +NYCRN
Sbjct: 932 EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P PWC+T++P VR+E C++ +CS+ E
Sbjct: 992 P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C G+SYRG T +G+ CQ W TPH+H PE YP+ G NYCRNPD +
Sbjct: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
Query: 263 RPWCYTLDPHTRWEYCAIKTC----------------ADNTMNDTDVPLETT----ECIQ 302
RPWCYT+DP RWEYC + C + + P E + +C
Sbjct: 1111 RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYH 1170
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ YRG+ +T G CQ W S PH H T E + L NYCRNPD SPWC+T
Sbjct: 1171 GDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYT 1230
Query: 363 TDPNIRVGYCS--------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQTR 402
DPN+R YC+ Q P QDCY G+G++Y G+ S T
Sbjct: 1231 MDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTV 1290
Query: 403 SGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPIS 462
+G TC W H+ L NYCRNPD + PWCYT +P + W+YC ++
Sbjct: 1291 TGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLT 1349
Query: 463 RCEGD-----TTPTIV 473
+C TTPT+V
Sbjct: 1350 QCPVMESTLLTTPTVV 1365
Score = 308 bits (789), Expect = 1e-83
Identities = 164/438 (37%), Positives = 213/438 (48%), Gaps = 86/438 (19%)
Query: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYC 172
L E +++C G+SY+GT S T +G CQ WSSM PH+HS Y L NYC
Sbjct: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
Query: 173 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE--------------------------- 205
RNP E PWC+T +P VR+E C++ QC E
Sbjct: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
Query: 206 -----CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C +G+SYRG T +G+ CQ W TPH H+ E YP+ G NYCRNPD
Sbjct: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
Query: 261 QPRPWCYTLDPHTRWEYCAIKTC--------ADNTMNDTDVPLETT----ECIQGQGEGY 308
+ PWCYT+DP+ RWEYC + C A +T P E + +C G G+ Y
Sbjct: 1223 EISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSY 1282
Query: 309 RGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIR 368
RG+ +T G CQ W S PH H T E + L NYCRNPD PWC+T DP++R
Sbjct: 1283 RGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVR 1342
Query: 369 VGYCS----------------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQ 400
YC+ + P + + QDCYRG+G++Y G LS
Sbjct: 1343 WEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLST 1402
Query: 401 TRSGLTCSMWDKNMEDLHRHI-FWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYC 459
T +G TC W HR I + P+A L NYCRNPD + PWCYT +P + W+YC
Sbjct: 1403 TITGRTCQSWSSMTPHWHRRIPLYYPNAG-LTRNYCRNPDAEIR-PWCYTMDPSVRWEYC 1460
Query: 460 PISRCEGD-----TTPTI 472
++RC TTPT+
Sbjct: 1461 NLTRCPVTESSVLTTPTV 1478
Score = 301 bits (770), Expect = 2e-81
Identities = 159/437 (36%), Positives = 211/437 (48%), Gaps = 86/437 (19%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E +++C G G+SY+G+ S T +G CQ WSSM PH H Y L NYCRN
Sbjct: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE------------------------CMTCN 210
P E PWC+T +P VR+E C++ QC E C +
Sbjct: 1220 PDAEI-SPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
Query: 211 GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLD 270
G+SYRG T +G+ CQ W TPH H+ E YP+ G NYCRNPD + RPWCYT+D
Sbjct: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
Query: 271 PHTRWEYCAIKTC--ADNTM--NDTDVPLETTE----------------CIQGQGEGYRG 310
P RWEYC + C ++T+ T VP+ +TE C +G G+ YRG
Sbjct: 1339 PSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRG 1398
Query: 311 TVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVG 370
T++T G CQ W S PH H P + L NYCRNPD PWC+T DP++R
Sbjct: 1399 TLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWE 1458
Query: 371 YCSQIPNCDMSHG-----------------------------QDCYRGNGKNYMGNLSQT 401
YC+ + C ++ QDCY G+G++Y G S T
Sbjct: 1459 YCN-LTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTT 1517
Query: 402 RSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPI 461
+G TC W + H+ + L ENYCRNPD PWCYT +P + W+YC +
Sbjct: 1518 VTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYTTDPCVRWEYCNL 1576
Query: 462 SRCEGD-----TTPTIV 473
++C TPT+V
Sbjct: 1577 TQCSETESGVLETPTVV 1593
Score = 293 bits (750), Expect = 4e-79
Identities = 159/432 (36%), Positives = 204/432 (47%), Gaps = 91/432 (21%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 590 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 650 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 709 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
Query: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302
P+CYT DP RWEYC + C+D + + P E EC
Sbjct: 769 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 828
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ YRGT +T G CQ W S PH H TPE + L NYCRNPD +P+C+T
Sbjct: 829 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYT 888
Query: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393
DP++R YC+ + C + G Q+CY GNG++
Sbjct: 889 RDPSVRWEYCN-LTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQS 947
Query: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452
Y G T +G TC W H R + P+A L +NYCRNPD A PWCYT +P
Sbjct: 948 YQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAG-LIKNYCRNPDPVA-APWCYTTDP 1005
Query: 453 LIPWDYCPISRC 464
+ W+YC ++RC
Sbjct: 1006 SVRWEYCNLTRC 1017
Score = 288 bits (738), Expect = 9e-78
Identities = 158/432 (36%), Positives = 203/432 (46%), Gaps = 91/432 (21%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 194 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
Query: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302
P+CYT DP RWEYC + C+D + + P E EC
Sbjct: 313 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 372
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ YRGT +T G CQ W S PH H TPE + L NYCRNPD +P+C+T
Sbjct: 373 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 432
Query: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393
DP +R YC+ + C + G Q+CY GNG++
Sbjct: 433 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 491
Query: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452
Y G S T +G TC W H R + P+A L NYCRNPD A P+CYT +P
Sbjct: 492 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 549
Query: 453 LIPWDYCPISRC 464
+ W+YC +++C
Sbjct: 550 GVRWEYCNLTQC 561
Score = 288 bits (738), Expect = 9e-78
Identities = 158/432 (36%), Positives = 203/432 (46%), Gaps = 91/432 (21%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 308 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
Query: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302
P+CYT DP RWEYC + C+D + + P E EC
Sbjct: 427 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 486
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ YRGT +T G CQ W S PH H TPE + L NYCRNPD +P+C+T
Sbjct: 487 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 546
Query: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393
DP +R YC+ + C + G Q+CY GNG++
Sbjct: 547 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 605
Query: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452
Y G S T +G TC W H R + P+A L NYCRNPD A P+CYT +P
Sbjct: 606 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 663
Query: 453 LIPWDYCPISRC 464
+ W+YC +++C
Sbjct: 664 GVRWEYCNLTQC 675
Score = 288 bits (738), Expect = 9e-78
Identities = 158/432 (36%), Positives = 203/432 (46%), Gaps = 91/432 (21%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 422 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
Query: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302
P+CYT DP RWEYC + C+D + + P E EC
Sbjct: 541 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ YRGT +T G CQ W S PH H TPE + L NYCRNPD +P+C+T
Sbjct: 601 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660
Query: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393
DP +R YC+ + C + G Q+CY GNG++
Sbjct: 661 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 719
Query: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452
Y G S T +G TC W H R + P+A L NYCRNPD A P+CYT +P
Sbjct: 720 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 777
Query: 453 LIPWDYCPISRC 464
+ W+YC +++C
Sbjct: 778 GVRWEYCNLTQC 789
Score = 288 bits (737), Expect = 1e-77
Identities = 157/432 (36%), Positives = 204/432 (47%), Gaps = 91/432 (21%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E +++C G G+SY+GT S T +G CQ WSSM PH+H+ Y L NYCRN
Sbjct: 20 EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 80 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302
P+CYT DP RWEYC + C+D + + P E EC
Sbjct: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ YRGT +T G CQ W S PH H TPE + L NYCRNPD +P+C+T
Sbjct: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 318
Query: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393
DP +R YC+ + C + G Q+CY GNG++
Sbjct: 319 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 377
Query: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452
Y G S T +G TC W H R + P+A L NYCRNPD A P+CYT +P
Sbjct: 378 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 435
Query: 453 LIPWDYCPISRC 464
+ W+YC +++C
Sbjct: 436 GVRWEYCNLTQC 447
Score = 285 bits (729), Expect = 1e-76
Identities = 153/430 (35%), Positives = 197/430 (45%), Gaps = 87/430 (20%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 704 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 764 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 823 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
Query: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302
P+CYT DP RWEYC + C+D + + P E EC
Sbjct: 883 APYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYH 942
Query: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362
G G+ Y+GT G CQ W S PH H TP + L +NYCRNPD +PWC+T
Sbjct: 943 GNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYT 1002
Query: 363 TDPNIRVGYCSQI------------PNCDMSHG----------------QDCYRGNGKNY 394
TDP++R YC+ PN ++ QDCY G++Y
Sbjct: 1003 TDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSY 1062
Query: 395 MGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLI 454
G S T +G TC W H + L NYCRNPD + PWCYT +P +
Sbjct: 1063 RGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIR-PWCYTMDPSV 1121
Query: 455 PWDYCPISRC 464
W+YC +++C
Sbjct: 1122 RWEYCNLTQC 1131
Score = 221 bits (563), Expect = 2e-57
Identities = 118/318 (37%), Positives = 154/318 (48%), Gaps = 55/318 (17%)
Query: 199 PQCSEV--ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCR 256
P+ S V +C +G+SYRG T +G+ CQ W TPH+H E YP+ G NYCR
Sbjct: 19 PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
Query: 257 NPDGQPRPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT------- 298
NPD P+CYT DP RWEYC + C+D + + P E
Sbjct: 79 NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 299 --ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSE 356
EC G G+ YRGT +T G CQ W S PH H TPE + L NYCRNPD
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 357 SPWCFTTDPNIRVGYCSQIPNCDMSHG-----------------------------QDCY 387
+P+C+T DP +R YC+ + C + G Q+CY
Sbjct: 199 APYCYTRDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 257
Query: 388 RGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPW 446
GNG++Y G S T +G TC W H R + P+A L NYCRNPD A P+
Sbjct: 258 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APY 315
Query: 447 CYTGNPLIPWDYCPISRC 464
CYT +P + W+YC +++C
Sbjct: 316 CYTRDPGVRWEYCNLTQC 333
>gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo
sapiens]
Length = 210
Score = 427 bits (1098), Expect = e-119
Identities = 203/208 (97%), Positives = 203/208 (97%), Gaps = 5/208 (2%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 203
RGEEGGPWCFTSNPEVRYEVCDIPQCSE
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
Score = 97.8 bits (242), Expect = 3e-20
Identities = 42/80 (52%), Positives = 53/80 (66%), Gaps = 2/80 (2%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSE-SP 358
CI G+G Y+GTV+ +GI CQ W S PHEH P +++ KDL+ENYCRNP G E P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 359 WCFTTDPNIRVGYCSQIPNC 378
WCFT++P +R C IP C
Sbjct: 188 WCFTSNPEVRYEVC-DIPQC 206
Score = 86.3 bits (212), Expect = 9e-17
Identities = 36/81 (44%), Positives = 47/81 (58%), Gaps = 1/81 (1%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP-RP 264
C+ G SY+G + T+SG CQ W PH H FLP Y K +NYCRNP G+ P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 265 WCYTLDPHTRWEYCAIKTCAD 285
WC+T +P R+E C I C++
Sbjct: 188 WCFTSNPEVRYEVCDIPQCSE 208
Score = 74.7 bits (182), Expect = 3e-13
Identities = 30/81 (37%), Positives = 45/81 (55%)
Query: 384 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 443
++C G G++Y G +S T+SG+ C W + H + L ENYCRNP +
Sbjct: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
Query: 444 GPWCYTGNPLIPWDYCPISRC 464
GPWC+T NP + ++ C I +C
Sbjct: 186 GPWCFTSNPEVRYEVCDIPQC 206
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 180 bits (456), Expect = 5e-45
Identities = 132/452 (29%), Positives = 200/452 (44%), Gaps = 62/452 (13%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDS----QYPHEHDMTPENFKCKDLRENYCRNPDGS 355
C + QG YRGT +T +G C W+S Q P+ P+ + NYCRNPD
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNHNYCRNPDRD 185
Query: 356 ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME 415
PWC+ P C + DCY GNG Y G S T SG +C W+ +
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEGNS-DCYFGNGSAYRGTHSLTESGASCLPWNSMIL 244
Query: 416 DLHRHIFWEPDASKLN---ENYCRNPDDDAHGPWCYT-GNPLIPWDYCPISRCEGDTTPT 471
+ P A L NYCRNPD DA PWC+ N + W+YC + C +T
Sbjct: 245 IGKVYTAQNPSAQALGLGKHNYCRNPDGDAK-PWCHVLKNRRLTWEYCDVPSC---STCG 300
Query: 472 IVNLDHPVISCAKTKQLRVVNGI-PTRTNIGWMVSLRYRNKH------ICGGSLIKESWV 524
+ P Q R+ G+ + W ++ +++ +CGG LI W+
Sbjct: 301 LRQYSQP--------QFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWI 352
Query: 525 LTARQCFPSRDLKDYEAWLGIHDVHGR------GDEKCKQVLNVSQLVYGPE------GS 572
L+A CF R + + + GR G+E+ Q V + + E +
Sbjct: 353 LSAAHCFQERFPPHH-----LTVILGRTYRVVPGEEE--QKFEVEKYIVHKEFDDDTYDN 405
Query: 573 DLVLMKL----ARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLIN--YDGLLRV 626
D+ L++L +R A V T+ LP +P+ T C + G+G ++ Y L+
Sbjct: 406 DIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKE 465
Query: 627 AHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGP-------CEGDYGGPLVCEQHKM 679
AH+ + + +C+ H T+ ++ +CAG + G GP C+GD GGPLVC
Sbjct: 466 AHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSG-GPQANLHDACQGDSGGPLVCLNDGR 524
Query: 680 RMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 711
++G+I G GC + PG++ +V Y WI
Sbjct: 525 MTLVGIISWGLGCGQKDVPGVYTKVTNYLDWI 556
Score = 102 bits (255), Expect = 1e-21
Identities = 58/172 (33%), Positives = 80/172 (46%), Gaps = 16/172 (9%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQ--------ENYCRNPRGEE 179
C +G SY+GT S +SG +C W+S + Y G+ NYCRNP +
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 185
Query: 180 GGPWCFTSNP-EVRYEVCDIPQCSE--VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 236
PWC+ + E C P CSE +C NG +YRG TESG C W+
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 245
Query: 237 RHKFLPERYPDKGFD---DNYCRNPDGQPRPWCYTL-DPHTRWEYCAIKTCA 284
+ + + NYCRNPDG +PWC+ L + WEYC + +C+
Sbjct: 246 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS 297
Score = 96.3 bits (238), Expect = 9e-20
Identities = 69/227 (30%), Positives = 95/227 (41%), Gaps = 36/227 (15%)
Query: 172 CRNPRGEEGGPWCFTSNPEVRYE--VCDIPQ-----CSEVE----CMTCNGESYRGLMDH 220
C PR GG T + + VC P+ C E++ C G SYRG
Sbjct: 86 CSEPRCFNGG----TCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWST 141
Query: 221 TESGKICQRWDHQTPHRHKFLPERYPDK---GFDD-NYCRNPDGQPRPWCYTLDPHT-RW 275
ESG C W+ + + R PD G + NYCRNPD +PWCY
Sbjct: 142 AESGAECTNWNSSALAQKPYSGRR-PDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSS 200
Query: 276 EYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMT 335
E+C+ C++ ++C G G YRGT + +G C W+S T
Sbjct: 201 EFCSTPACSEGN----------SDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYT 250
Query: 336 PENFKCKDL---RENYCRNPDGSESPWCFT-TDPNIRVGYCSQIPNC 378
+N + L + NYCRNPDG PWC + + YC +P+C
Sbjct: 251 AQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYC-DVPSC 296
Score = 69.7 bits (169), Expect = 9e-12
Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 15/97 (15%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDL--------QENYCRNPRGE 178
+C G G +Y+GT S+T+SG C PW+SMI Y ++ + NYCRNP G
Sbjct: 214 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 272
Query: 179 EGGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESY 214
+ PWC N + +E CD+P CS TC Y
Sbjct: 273 DAKPWCHVLKNRRLTWEYCDVPSCS-----TCGLRQY 304
Score = 56.6 bits (135), Expect = 8e-08
Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 378 CDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKL---NENY 434
C++ CY G +Y G S SG C+ W+ + + PDA +L N NY
Sbjct: 119 CEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNY 178
Query: 435 CRNPDDDAHGPWCY 448
CRNPD D+ PWCY
Sbjct: 179 CRNPDRDSK-PWCY 191
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 180 bits (456), Expect = 5e-45
Identities = 132/452 (29%), Positives = 200/452 (44%), Gaps = 62/452 (13%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDS----QYPHEHDMTPENFKCKDLRENYCRNPDGS 355
C + QG YRGT +T +G C W+S Q P+ P+ + NYCRNPD
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNHNYCRNPDRD 139
Query: 356 ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME 415
PWC+ P C + DCY GNG Y G S T SG +C W+ +
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEGNS-DCYFGNGSAYRGTHSLTESGASCLPWNSMIL 198
Query: 416 DLHRHIFWEPDASKLN---ENYCRNPDDDAHGPWCYT-GNPLIPWDYCPISRCEGDTTPT 471
+ P A L NYCRNPD DA PWC+ N + W+YC + C +T
Sbjct: 199 IGKVYTAQNPSAQALGLGKHNYCRNPDGDAK-PWCHVLKNRRLTWEYCDVPSC---STCG 254
Query: 472 IVNLDHPVISCAKTKQLRVVNGI-PTRTNIGWMVSLRYRNKH------ICGGSLIKESWV 524
+ P Q R+ G+ + W ++ +++ +CGG LI W+
Sbjct: 255 LRQYSQP--------QFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWI 306
Query: 525 LTARQCFPSRDLKDYEAWLGIHDVHGR------GDEKCKQVLNVSQLVYGPE------GS 572
L+A CF R + + + GR G+E+ Q V + + E +
Sbjct: 307 LSAAHCFQERFPPHH-----LTVILGRTYRVVPGEEE--QKFEVEKYIVHKEFDDDTYDN 359
Query: 573 DLVLMKL----ARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLIN--YDGLLRV 626
D+ L++L +R A V T+ LP +P+ T C + G+G ++ Y L+
Sbjct: 360 DIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKE 419
Query: 627 AHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGP-------CEGDYGGPLVCEQHKM 679
AH+ + + +C+ H T+ ++ +CAG + G GP C+GD GGPLVC
Sbjct: 420 AHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSG-GPQANLHDACQGDSGGPLVCLNDGR 478
Query: 680 RMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 711
++G+I G GC + PG++ +V Y WI
Sbjct: 479 MTLVGIISWGLGCGQKDVPGVYTKVTNYLDWI 510
Score = 102 bits (255), Expect = 1e-21
Identities = 58/172 (33%), Positives = 80/172 (46%), Gaps = 16/172 (9%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQ--------ENYCRNPRGEE 179
C +G SY+GT S +SG +C W+S + Y G+ NYCRNP +
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 139
Query: 180 GGPWCFTSNP-EVRYEVCDIPQCSE--VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 236
PWC+ + E C P CSE +C NG +YRG TESG C W+
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 199
Query: 237 RHKFLPERYPDKGFD---DNYCRNPDGQPRPWCYTL-DPHTRWEYCAIKTCA 284
+ + + NYCRNPDG +PWC+ L + WEYC + +C+
Sbjct: 200 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS 251
Score = 96.3 bits (238), Expect = 9e-20
Identities = 69/227 (30%), Positives = 95/227 (41%), Gaps = 36/227 (15%)
Query: 172 CRNPRGEEGGPWCFTSNPEVRYE--VCDIPQ-----CSEVE----CMTCNGESYRGLMDH 220
C PR GG T + + VC P+ C E++ C G SYRG
Sbjct: 40 CSEPRCFNGG----TCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWST 95
Query: 221 TESGKICQRWDHQTPHRHKFLPERYPDK---GFDD-NYCRNPDGQPRPWCYTLDPHT-RW 275
ESG C W+ + + R PD G + NYCRNPD +PWCY
Sbjct: 96 AESGAECTNWNSSALAQKPYSGRR-PDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSS 154
Query: 276 EYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMT 335
E+C+ C++ ++C G G YRGT + +G C W+S T
Sbjct: 155 EFCSTPACSEGN----------SDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYT 204
Query: 336 PENFKCKDL---RENYCRNPDGSESPWCFT-TDPNIRVGYCSQIPNC 378
+N + L + NYCRNPDG PWC + + YC +P+C
Sbjct: 205 AQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYC-DVPSC 250
Score = 69.7 bits (169), Expect = 9e-12
Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 15/97 (15%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDL--------QENYCRNPRGE 178
+C G G +Y+GT S+T+SG C PW+SMI Y ++ + NYCRNP G
Sbjct: 168 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 226
Query: 179 EGGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESY 214
+ PWC N + +E CD+P CS TC Y
Sbjct: 227 DAKPWCHVLKNRRLTWEYCDVPSCS-----TCGLRQY 258
Score = 57.4 bits (137), Expect = 5e-08
Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 14/112 (12%)
Query: 350 RNPDGSESPWCFTTDPNIRVGYCS----QIPN------CDMSHGQDCYRGNGKNYMGNLS 399
R+ G P CF + Y S Q P C++ CY G +Y G S
Sbjct: 35 RSYQGCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWS 94
Query: 400 QTRSGLTCSMWDKNMEDLHRHIFWEPDASKL---NENYCRNPDDDAHGPWCY 448
SG C+ W+ + + PDA +L N NYCRNPD D+ PWCY
Sbjct: 95 TAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSK-PWCY 145
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 160 bits (406), Expect = 3e-39
Identities = 110/368 (29%), Positives = 165/368 (44%), Gaps = 36/368 (9%)
Query: 378 CDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLN---ENY 434
C++ + C+ GNG Y G S + SGL+C W+ ++ H+ A+ L Y
Sbjct: 278 CNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAY 337
Query: 435 CRNPDDDAHGPWCYT-GNPLIPWDYCPISRCEGDTT-----PTIVNLDHPVI----SCAK 484
CRNPD+D PWCY + + W+YC + CE T + L P +C +
Sbjct: 338 CRNPDNDER-PWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQACGR 396
Query: 485 TKQLR------VVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCF---PSRD 535
+ R ++ G + ++ Y C GSL+ WV++A CF P RD
Sbjct: 397 RHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRD 456
Query: 536 LKDYEAWLGIHDVHGRGDEKC-----KQVLNVSQLVYGPEGSDLVLMKLA----RPAVLD 586
LG H + D K + V+ P DLVL++L R A
Sbjct: 457 --SVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRS 514
Query: 587 DFVSTIDLPNYGCTIPEKTSCSVYGWGYT--GLINYDGLLRVAHLYIMGNEKCSQHHRGK 644
FV I LP G T P C + GWG+ + Y LR A + ++ + KCS
Sbjct: 515 QFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYG 574
Query: 645 VTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRV 704
++ + +CAG S C+GD GGPL CE++ + + G+I G GC ++PG++ RV
Sbjct: 575 ADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRV 634
Query: 705 AYYAKWIH 712
A Y WI+
Sbjct: 635 ANYVDWIN 642
Score = 56.6 bits (135), Expect = 8e-08
Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 6/87 (6%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWD----HQTPHRHKFLPERYPDKGFDDNYCRNPDGQ 261
C NG YRG+ + SG C W+ +Q H G YCRNPD
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLG-PHAYCRNPDND 344
Query: 262 PRPWCYTL-DPHTRWEYCAIKTCADNT 287
RPWCY + D WEYC ++ C T
Sbjct: 345 ERPWCYVVKDSALSWEYCRLEACESLT 371
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLR----ENYCRNPDGS 355
C G G GYRG +T +G+ C W+S ++ ++ ++ L YCRNPD
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQ-ELHVDSVGAAALLGLGPHAYCRNPDND 344
Query: 356 ESPWCFTT-DPNIRVGYC 372
E PWC+ D + YC
Sbjct: 345 ERPWCYVVKDSALSWEYC 362
Score = 46.6 bits (109), Expect = 8e-05
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMI----PHEHSYRGKDL----QENYCRNPRGEE 179
C +G G Y+G S + SG+ C W+S + H S L YCRNP +E
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
Query: 180 GGPWCF-TSNPEVRYEVCDIPQCSEV 204
PWC+ + + +E C + C +
Sbjct: 346 -RPWCYVVKDSALSWEYCRLEACESL 370
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 156 bits (394), Expect = 7e-38
Identities = 144/566 (25%), Positives = 223/566 (39%), Gaps = 102/566 (18%)
Query: 201 CSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C E C G +YRG ++ T SG CQ W + PH+ + +P +N+CRNPD
Sbjct: 103 CLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDS 162
Query: 261 QPR-PWCYTLDPHTRWEYCAIKTCADNTMN------------DTDVPLETTECIQGQGEG 307
PWCYT DP R + C+I C + + + PLE +C+ +G+
Sbjct: 163 STTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLE--QCVPDRGQQ 220
Query: 308 YRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESP-WCFTTDPN 366
Y+G + +G+PC W S + L EN+CRNPDG E WC+
Sbjct: 221 YQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKP 280
Query: 367 IRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPD 426
GY CD+++ ++ +T GL ED R I
Sbjct: 281 GDFGY------CDLNYCEEAVE----------EETGDGLD--------EDSDRAIEGRTA 316
Query: 427 ASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK 486
S+ + NP G PL + E + + ++
Sbjct: 317 TSEYQTFF--NPRTFGSGEADCGLRPLFEKKSLE-DKTERELLESYIDG----------- 362
Query: 487 QLRVVNGIPTRTNIG-WMVSLRYRNKH--ICGGSLIKESWVLTARQC--FPSRDL----K 537
R+V G + W V L ++ +CG SLI + WVLTA C +P D
Sbjct: 363 --RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 420
Query: 538 DYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPE-------GSDLVLMKLARPAVLDDFVS 590
D +G H R + +++ + ++ P D+ LMKL +P D++
Sbjct: 421 DLLVRIGKHS-RTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 479
Query: 591 TIDLPNYGCTIPEKTSCSVYGWGYTGLINYDG----------------LLRVAHLYIMGN 634
+ LP+ +T+ S+ GY G + G +L+V +L I+
Sbjct: 480 PVCLPD------RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 533
Query: 635 EKCSQHHRGKVTLNESEICAG---AEKIGSGPCEGDYGGPLVCEQ--HKMRMVLGVIVPG 689
C R ++T ++ CAG E CEGD GGP V + + +G++ G
Sbjct: 534 PVCKDSTRIRIT--DNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 591
Query: 690 RGCAIPNRPGIFVRVAYYAKWIHKII 715
GC + G + V KWI K+I
Sbjct: 592 EGCDRDGKYGFYTHVFRLKKWIQKVI 617
Score = 115 bits (287), Expect = 2e-25
Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 28/193 (14%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEEGG 181
NC G G +Y+G V+IT+SGI+CQ W S PH+ ++ G DLQEN+CRNP G
Sbjct: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
Query: 182 PWCFTSNPEVRYEVCDIPQCSE----------------------VECMTCNGESYRGLMD 219
PWC+T++P VR + C IP C + +C+ G+ Y+G +
Sbjct: 167 PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLA 226
Query: 220 HTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG-QPRPWCYTLDPHTRWEYC 278
T G C W + +N+CRNPDG + WCY + YC
Sbjct: 227 VTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYC 286
Query: 279 AIKTCADNTMNDT 291
+ C + +T
Sbjct: 287 DLNYCEEAVEEET 299
Score = 64.3 bits (155), Expect = 4e-10
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSS-----MIPHEHSYRGKDLQENYCRNPRGEE 179
+ C+ +G+ Y+G +++T G+ C W+S + H+ L EN+CRNP G+E
Sbjct: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269
Query: 180 GGPWCFTSNPEVRYEVCDIPQCSE 203
G WC+ + + CD+ C E
Sbjct: 270 EGVWCYVAGKPGDFGYCDLNYCEE 293
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 142 bits (358), Expect = 1e-33
Identities = 143/551 (25%), Positives = 210/551 (38%), Gaps = 107/551 (19%)
Query: 262 PRPWCYT---LDPHTRWEYCAI-KTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWN 317
P+PWC T D RW YC K D+ + P + G
Sbjct: 69 PQPWCATTPNFDQDQRWGYCLEPKKVKDHCSKHS--PCQKGGTCVNMPSGPHCLCPQHLT 126
Query: 318 GIPCQRWDSQYP------HEHDMTPENFKCKDLRENYCRNPDGS----ESPWCFTTDPNI 367
G CQ+ P H++++ + R C+ PD S C T+P +
Sbjct: 127 GNHCQKEKCFEPQLLRFFHKNEIWYRTEQAAVARCQ-CKGPDAHCQRLASQAC-RTNPCL 184
Query: 368 RVGYCSQIPN--------------CDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKN 413
G C ++ CD+ CY G G +Y G T SG C W
Sbjct: 185 HGGRCLEVEGHRLCHCPVGYTGAFCDVDTKASCYDGRGLSYRGLARTTLSGAPCQPWAS- 243
Query: 414 MEDLHRHIFWEPDAS--KLNENYCRNPDDDAHGPWCYTGN-PLIPWDYCPISRCEGDT-- 468
E +R++ E + +CRNPD+D PWC+ N + W+YC +++C+ T
Sbjct: 244 -EATYRNVTAEQARNWGLGGHAFCRNPDNDIR-PWCFVLNRDRLSWEYCDLAQCQTPTQA 301
Query: 469 ---TPTIVNLDHPV-----------------------------------------ISCAK 484
TP L P+ +SC +
Sbjct: 302 APPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCGQ 361
Query: 485 ------TKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDL-K 537
+ RVV G+ ++ Y C GSLI WVLTA C R +
Sbjct: 362 RLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPE 421
Query: 538 DYEAWLGIHDVHGRGDEKCKQVLNVSQLV---YGPEG--SDLVLMKLARPA-----VLDD 587
D LG + E C+ + S + + P DL L++L A +L
Sbjct: 422 DLTVVLG-QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSP 480
Query: 588 FVSTIDLPNYGCTIPEKTSCSVYGWG--YTGLINYDGLLRVAHLYIMGNEKCSQHHRGKV 645
+V + LP+ E T C V GWG + G Y L+ A + + E+CS
Sbjct: 481 YVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS 540
Query: 646 TLNESEICAGAEKIGSGPCEGDYGGPLVCEQH--KMRMVL-GVIVPGRGCAIPNRPGIFV 702
++ +CAG + G+ C+GD GGPLVCE + R+ L G+I G GC N+PG++
Sbjct: 541 SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYT 600
Query: 703 RVAYYAKWIHK 713
VAYY WI +
Sbjct: 601 DVAYYLAWIRE 611
Score = 62.0 bits (149), Expect = 2e-09
Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Query: 196 CDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDN-Y 254
CD+ ++ C G SYRGL T SG CQ W + +R+ E+ + G + +
Sbjct: 209 CDVD--TKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRN-VTAEQARNWGLGGHAF 265
Query: 255 CRNPDGQPRPWCYTLD-PHTRWEYCAIKTCADNTMNDTDVPL 295
CRNPD RPWC+ L+ WEYC + C T P+
Sbjct: 266 CRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQTPTQAAPPTPV 307
Score = 56.6 bits (135), Expect = 8e-08
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 15/85 (17%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQE---------NYCRNPRG 177
+C G+G SY+G T SG CQPW+S E +YR ++ +CRNP
Sbjct: 216 SCYDGRGLSYRGLARTTLSGAPCQPWAS----EATYRNVTAEQARNWGLGGHAFCRNP-D 270
Query: 178 EEGGPWCFTSNPE-VRYEVCDIPQC 201
+ PWCF N + + +E CD+ QC
Sbjct: 271 NDIRPWCFVLNRDRLSWEYCDLAQC 295
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 139 bits (350), Expect = 9e-33
Identities = 116/418 (27%), Positives = 179/418 (42%), Gaps = 46/418 (11%)
Query: 325 DSQYPHEHDMTPENFKCKDLRENYC-RNPDGSESPWCFTTDPNIRVGYCSQIPNCDMSHG 383
DS+ +E P N C L C N S WC N + Q +C++
Sbjct: 17 DSKGSNELHQVPSNCDC--LNGGTCVSNKYFSNIHWC-----NCPKKFGGQ--HCEIDKS 67
Query: 384 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKN---MEDLHRHIFWEPDASKLN---ENYCRN 437
+ CY GNG Y G S G C W+ + H H DA +L NYCRN
Sbjct: 68 KTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH---RSDALQLGLGKHNYCRN 124
Query: 438 PDDDAHGPWCYTGNPLIPW-DYCPISRCEGDTTPTIVNLDHPVISCAKT--KQLRVVNG- 493
PD+ PWCY L P C + C P+ + KT + +++ G
Sbjct: 125 PDNRRR-PWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGE 183
Query: 494 IPTRTNIGWMVSLRYRNK-----HICGGSLIKESWVLTARQCFPSRDLK-DYEAWLGIHD 547
T N W ++ R++ ++CGGSLI WV++A CF K DY +LG
Sbjct: 184 FTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSR 243
Query: 548 VHGRGDEKCKQVLNVSQLVYGPEGS--------DLVLMKL----ARPAVLDDFVSTIDLP 595
++ + K V L+ + S D+ L+K+ R A + TI LP
Sbjct: 244 LNSNTQGEMK--FEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLP 301
Query: 596 NYGCTIPEKTSCSVYGWGYTGLINY--DGLLRVAHLYIMGNEKCSQHHRGKVTLNESEIC 653
+ TSC + G+G +Y L++ + ++ + +C Q H + +C
Sbjct: 302 SMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLC 361
Query: 654 AGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 711
A + + C+GD GGPLVC + G++ GRGCA+ ++PG++ RV+++ WI
Sbjct: 362 AADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWI 419
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 15/95 (15%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDS-----QYPHEHDMTPENFKCKDLRENYCRNPDG 354
C +G G YRG +T G PC W+S Q H H + + + NYCRNPD
Sbjct: 70 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH--RSDALQLGLGKHNYCRNPDN 127
Query: 355 SESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRG 389
PWC+ ++VG + C M H DC G
Sbjct: 128 RRRPWCY-----VQVGLKPLVQEC-MVH--DCADG 154
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 12/88 (13%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWD-----HQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C NG YRG G+ C W+ QT H H+ + NYCRNPD
Sbjct: 70 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHR--SDALQLGLGKHNYCRNPDN 127
Query: 261 QPRPWCYT---LDPHTRWEYCAIKTCAD 285
+ RPWCY L P + C + CAD
Sbjct: 128 RRRPWCYVQVGLKPLV--QECMVHDCAD 153
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHE---HSYRGKDLQ-----ENYCRN 174
D + C G G Y+G S G C PW+S + H++R LQ NYCRN
Sbjct: 65 DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRN 124
Query: 175 PRGEEGGPWCF 185
P PWC+
Sbjct: 125 PDNRR-RPWCY 134
>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
Length = 560
Score = 137 bits (346), Expect = 3e-32
Identities = 107/370 (28%), Positives = 163/370 (44%), Gaps = 47/370 (12%)
Query: 385 DCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLN---ENYCRNPDDD 441
DCY G+G +Y G +++T + C W+ ++ + + DA N+CRNPD D
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 442 AHGPWCY--TGNPLIPWDYCPISRCEG------DTTPTIVNLDHPVI-SCAKT-----KQ 487
PWC+ N + W+YC +S C + +PT + P SC KT K
Sbjct: 253 EK-PWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKI 311
Query: 488 LRVVNGIP-TRTNIGWMVSLRYR--------NKHICGGSLIKESWVLTARQCFPSRDLKD 538
R+ G T W SL+ H CGG+LI WVLTA C D+K
Sbjct: 312 KRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHC---TDIKT 368
Query: 539 YEAWLGIHDVHGRGDEKCKQVLNVSQLV----YGPEG----SDLVLMKL----ARPAVLD 586
+ + D + +E +Q V ++ Y +D+ L+KL A+
Sbjct: 369 RHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALES 428
Query: 587 DFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVT 646
+V T+ LP+ + P + C + GWG T L A + ++ N C+
Sbjct: 429 KYVKTVCLPDG--SFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHM 486
Query: 647 LNESEICAG-AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVA 705
+++S ICAG +K G C+GD GGPL CE+ V G++ G C RPG++ +V
Sbjct: 487 IDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECG--KRPGVYTQVT 544
Query: 706 YYAKWIHKII 715
+ WI I
Sbjct: 545 KFLNWIKATI 554
Score = 57.4 bits (137), Expect = 5e-08
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
Query: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQT---PHRHKFLPERYPDKGFDDNYCRNPDGQ 261
+C +G SYRG M+ T + C W+ + + F+ + + N+CRNPD
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 262 PRPWCY--TLDPHTRWEYCAIKTC-ADNTMNDTDVPLETTECIQG 303
+PWC+ + +WEYC + C A + + P E + + G
Sbjct: 253 EKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPG 297
Score = 54.7 bits (130), Expect = 3e-07
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 11/86 (12%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR--GKDL------QENYCRNPRGE 178
+C +G G SY+G ++ T + C W+S + + +Y +D + N+CRNP +
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 179 EGGPWCF--TSNPEVRYEVCDIPQCS 202
E PWCF +N +V++E CD+ CS
Sbjct: 253 E-KPWCFIKVTNDKVKWEYCDVSACS 277
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 299 ECIQGQGEGYRGTVNTIWNGIPCQRWDSQY--PHEHDMTPENFKCKDLRE-NYCRNPDGS 355
+C G G YRG +N N C W+S ++M E+ + + E N+CRNPD
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 356 ESPWCF--TTDPNIRVGYC 372
E PWCF T+ ++ YC
Sbjct: 253 EKPWCFIKVTNDKVKWEYC 271
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 137 bits (345), Expect = 3e-32
Identities = 102/365 (27%), Positives = 162/365 (44%), Gaps = 36/365 (9%)
Query: 377 NCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKN---MEDLHRHIFWEPDASKLN-- 431
+C++ + CY GNG Y G S G C W+ + H H DA +L
Sbjct: 44 HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH---RSDALQLGLG 100
Query: 432 -ENYCRNPDDDAHGPWCYTGNPLIPW-DYCPISRCEGDTTPTIVNLDHPVISCAKT--KQ 487
NYCRNPD+ PWCY L P C + C P+ + KT +
Sbjct: 101 KHNYCRNPDNRRR-PWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPR 159
Query: 488 LRVVNG-IPTRTNIGWMVSLRYRNK-----HICGGSLIKESWVLTARQCFPSRDLK-DYE 540
+++ G T N W ++ R++ ++CGGSLI WV++A CF K DY
Sbjct: 160 FKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYI 219
Query: 541 AWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGS--------DLVLMKL----ARPAVLDDF 588
+LG ++ + K V L+ + S D+ L+K+ R A
Sbjct: 220 VYLGRSRLNSNTQGEMK--FEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRT 277
Query: 589 VSTIDLPNYGCTIPEKTSCSVYGWGYTGLINY--DGLLRVAHLYIMGNEKCSQHHRGKVT 646
+ TI LP+ TSC + G+G +Y L++ + ++ + +C Q H
Sbjct: 278 IQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSE 337
Query: 647 LNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAY 706
+ +CA + + C+GD GGPLVC + G++ GRGCA+ ++PG++ RV++
Sbjct: 338 VTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSH 397
Query: 707 YAKWI 711
+ WI
Sbjct: 398 FLPWI 402
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 11/93 (11%)
Query: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDL---RENYCRNPDGSE 356
C +G G YRG +T G PC W+S + L + NYCRNPD
Sbjct: 53 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 112
Query: 357 SPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRG 389
PWC+ ++VG + C M H DC G
Sbjct: 113 RPWCY-----VQVGLKPLVQEC-MVH--DCADG 137
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 12/88 (13%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWD-----HQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C NG YRG G+ C W+ QT H H+ + NYCRNPD
Sbjct: 53 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHR--SDALQLGLGKHNYCRNPDN 110
Query: 261 QPRPWCYT---LDPHTRWEYCAIKTCAD 285
+ RPWCY L P + C + CAD
Sbjct: 111 RRRPWCYVQVGLKPLV--QECMVHDCAD 136
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHE---HSYRGKDLQ-----ENYCRN 174
D + C G G Y+G S G C PW+S + H++R LQ NYCRN
Sbjct: 48 DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRN 107
Query: 175 PRGEEGGPWCF 185
P PWC+
Sbjct: 108 PDNRR-RPWCY 117
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 128 bits (322), Expect = 2e-29
Identities = 88/241 (36%), Positives = 125/241 (51%), Gaps = 30/241 (12%)
Query: 497 RTNIGWMVSLRYRNK---HICGGSLIKESWVLTARQCFPSRDLKDYEAW-LGIHDVHGRG 552
R+ W VSLR R++ H CGGSLI WVLTA C D+KD A + + + H
Sbjct: 39 RSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQLREQHLYY 97
Query: 553 DEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTS 606
+ Q+L VS+++ P+ G+D+ L++L P + V T+ LP T P
Sbjct: 98 QD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMP 154
Query: 607 CSVYGWGYTGLINYDGL-----LRVAHLYIMGNEKC-SQHHRGKVT------LNESEICA 654
C V GWG + N + L L+ + IM N C +++H G T + + +CA
Sbjct: 155 CWVTGWG--DVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCA 212
Query: 655 GAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKI 714
G + S C+GD GGPLVC+ + + GV+ G GCA PNRPGI+ RV YY WIH
Sbjct: 213 GNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270
Query: 715 I 715
+
Sbjct: 271 V 271
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 127 bits (318), Expect = 5e-29
Identities = 69/226 (30%), Positives = 118/226 (52%), Gaps = 17/226 (7%)
Query: 502 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 561
W+V L Y + +CG SL+ W+++A C R+L+ + W I +H + + Q +
Sbjct: 798 WVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSK-WTAILGLHMKSNLTSPQTVP 856
Query: 562 --VSQLVYGP------EGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWG 613
+ ++V P + +D+ +M L D++ I LP P +CS+ GWG
Sbjct: 857 RLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWG 916
Query: 614 YTGLINYDG----LLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYG 669
+ Y G +L+ A + ++ NE+C Q + + E+ ICAG E+ G C+GD G
Sbjct: 917 ---TVVYQGTTANILQEADVPLLSNERCQQQ-MPEYNITENMICAGYEEGGIDSCQGDSG 972
Query: 670 GPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
GPL+C+++ + GV G CA+PNRPG++ RV+ + +WI +
Sbjct: 973 GPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFL 1018
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 126 bits (316), Expect = 8e-29
Identities = 79/244 (32%), Positives = 125/244 (51%), Gaps = 19/244 (7%)
Query: 482 CAKTKQLRVVNGIPTRTNIG---WMVSLRYR---NKHICGGSLIKESWVLTARQCFPSRD 535
C R+V G T ++ G W VSL+ + +H+CGGSLI WVLTA CF
Sbjct: 383 CTTKTSTRIVGG--TNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLP 440
Query: 536 LKD----YEAWLGIHDV-HGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVS 590
L+D Y L + D+ + K+++ D+ L+KL P +F
Sbjct: 441 LQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK 500
Query: 591 TIDLPNYGCTIPEKTSCSVYGWGYT---GLINYDGLLRVAHLYIMGNEKCSQHHRGKVTL 647
I LP+ G T T+C V GWG++ G I +L+ ++ ++ NE+C + ++ +
Sbjct: 501 PICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQ--NILQKVNIPLVTNEECQKRYQD-YKI 557
Query: 648 NESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYY 707
+ +CAG ++ G C+GD GGPLVC+ + M ++G+ G GCA +PG++ +VA Y
Sbjct: 558 TQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEY 617
Query: 708 AKWI 711
WI
Sbjct: 618 MDWI 621
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 125 bits (313), Expect = 2e-28
Identities = 87/241 (36%), Positives = 122/241 (50%), Gaps = 30/241 (12%)
Query: 497 RTNIGWMVSLRYRNK---HICGGSLIKESWVLTARQCFPSRDLKDYEAW-LGIHDVHGRG 552
R+ W VSLR H CGGSLI WVLTA C D+KD A + + + H
Sbjct: 39 RSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQLREQHLYY 97
Query: 553 DEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTS 606
+ Q+L VS+++ P+ G+D+ L++L P + V T+ LP T P
Sbjct: 98 QD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMP 154
Query: 607 CSVYGWGYTGLINYDGL-----LRVAHLYIMGNEKC-SQHHRGKVT------LNESEICA 654
C V GWG + N + L L+ + IM N C +++H G T + + +CA
Sbjct: 155 CWVTGWG--DVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCA 212
Query: 655 GAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKI 714
G + S C+GD GGPLVC+ + + GV+ G GCA PNRPGI+ RV YY WIH
Sbjct: 213 GNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHY 270
Query: 715 I 715
+
Sbjct: 271 V 271
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 124 bits (312), Expect = 2e-28
Identities = 79/261 (30%), Positives = 120/261 (45%), Gaps = 20/261 (7%)
Query: 482 CAKTKQLRVVNGIPTRTNIG-WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKD-Y 539
C Q R+ G W VS+ Y H+CGGSL+ E WVL+A CFPS K+ Y
Sbjct: 37 CGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAY 96
Query: 540 EAWLGIHDVHGRGDEKCKQVLN--VSQLVYGPEGS--DLVLMKLARPAVLDDFVSTIDLP 595
E LG H + ++ L + Y EGS D+ L++L+RP ++ I LP
Sbjct: 97 EVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLP 156
Query: 596 NYGCTIPEKTSCSVYGWGYTG----LINYDGLLRVAHLYIMGNEKCSQHHRGKVT----- 646
+ P C+V GWG+ L+ L ++ + ++ E C+ +
Sbjct: 157 AANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQL-EVPLISRETCNCLYNIDAKPEEPH 215
Query: 647 -LNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVA 705
+ E +CAG + G C+GD GGPL C + + G++ G C NRPG++ +
Sbjct: 216 FVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLAS 275
Query: 706 YYAKWIHKIILTYK---VPQS 723
YA WI + + VPQ+
Sbjct: 276 SYASWIQSKVTELQPRVVPQT 296
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 122 bits (306), Expect = 1e-27
Identities = 78/250 (31%), Positives = 120/250 (48%), Gaps = 24/250 (9%)
Query: 489 RVVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGI 545
R+V G T++G W VSLRY H+CGGSL+ WVLTA CFP R+ + W
Sbjct: 162 RIVGG--RDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN-RVLSRWRVF 218
Query: 546 HDVHGRGDEKCKQVLNVSQLVY------------GPEGSDLVLMKLARPAVLDDFVSTID 593
+ Q L V +VY +D+ L+ L+ P L +++ +
Sbjct: 219 AGAVAQASPHGLQ-LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
Query: 594 LPNYGCTIPEKTSCSVYGWGYTGLINYD-GLLRVAHLYIMGNEKCSQHHRGKVTLNESEI 652
LP G + + C+V GWG T G+L+ A + I+ N+ C+ +
Sbjct: 278 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMF 337
Query: 653 CAGAEKIGSGPCEGDYGGPLVCEQHKMR----MVLGVIVPGRGCAIPNRPGIFVRVAYYA 708
CAG + G C+GD GGP VCE R + G++ G GCA+ +PG++ +V+ +
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 397
Query: 709 KWIHKIILTY 718
+WI + I T+
Sbjct: 398 EWIFQAIKTH 407
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 122 bits (306), Expect = 1e-27
Identities = 78/250 (31%), Positives = 120/250 (48%), Gaps = 24/250 (9%)
Query: 489 RVVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGI 545
R+V G T++G W VSLRY H+CGGSL+ WVLTA CFP R+ + W
Sbjct: 162 RIVGG--RDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN-RVLSRWRVF 218
Query: 546 HDVHGRGDEKCKQVLNVSQLVY------------GPEGSDLVLMKLARPAVLDDFVSTID 593
+ Q L V +VY +D+ L+ L+ P L +++ +
Sbjct: 219 AGAVAQASPHGLQ-LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
Query: 594 LPNYGCTIPEKTSCSVYGWGYTGLINYD-GLLRVAHLYIMGNEKCSQHHRGKVTLNESEI 652
LP G + + C+V GWG T G+L+ A + I+ N+ C+ +
Sbjct: 278 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMF 337
Query: 653 CAGAEKIGSGPCEGDYGGPLVCEQHKMR----MVLGVIVPGRGCAIPNRPGIFVRVAYYA 708
CAG + G C+GD GGP VCE R + G++ G GCA+ +PG++ +V+ +
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 397
Query: 709 KWIHKIILTY 718
+WI + I T+
Sbjct: 398 EWIFQAIKTH 407
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 121 bits (303), Expect = 3e-27
Identities = 75/237 (31%), Positives = 123/237 (51%), Gaps = 20/237 (8%)
Query: 486 KQLRVVNGIPT-RTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLG 544
+Q ++V+G P +T+ + +L +CGG LI WVLTA C + + +LG
Sbjct: 18 EQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLG 73
Query: 545 IHDVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYG 598
H++ R E ++ +V + V P+ D++L++LARPA L + + + L
Sbjct: 74 KHNLRQR--ESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLER-D 130
Query: 599 CTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEK 658
C+ TSC + GWG T ++ ++ A+++++ E+C + G++T N +CAG EK
Sbjct: 131 CS-ANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQN--MLCAGDEK 187
Query: 659 IGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
G C+GD GGPLVC H +V +P C +PG++ V Y WI K I
Sbjct: 188 YGKDSCQGDSGGPLVCGDHLRGLVSWGNIP---CGSKEKPGVYTNVCRYTNWIQKTI 241
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 121 bits (303), Expect = 3e-27
Identities = 75/237 (31%), Positives = 123/237 (51%), Gaps = 20/237 (8%)
Query: 486 KQLRVVNGIPT-RTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLG 544
+Q ++V+G P +T+ + +L +CGG LI WVLTA C + + +LG
Sbjct: 18 EQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLG 73
Query: 545 IHDVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYG 598
H++ R E ++ +V + V P+ D++L++LARPA L + + + L
Sbjct: 74 KHNLRQR--ESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLER-D 130
Query: 599 CTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEK 658
C+ TSC + GWG T ++ ++ A+++++ E+C + G++T N +CAG EK
Sbjct: 131 CS-ANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQN--MLCAGDEK 187
Query: 659 IGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
G C+GD GGPLVC H +V +P C +PG++ V Y WI K I
Sbjct: 188 YGKDSCQGDSGGPLVCGDHLRGLVSWGNIP---CGSKEKPGVYTNVCRYTNWIQKTI 241
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 120 bits (301), Expect = 4e-27
Identities = 78/234 (33%), Positives = 121/234 (51%), Gaps = 26/234 (11%)
Query: 502 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 561
W +L + + +CGG L+ WVLTA C + + +LG H + GR E +QV
Sbjct: 49 WQAALLVQGRLLCGGVLVHPKWVLTAAHCLK----EGLKVYLGKHAL-GRV-EAGEQVRE 102
Query: 562 VSQLVYGPE----------GSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYG 611
V + PE D++L++L P L ++ T+ L + P T+C V G
Sbjct: 103 VVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPG-TTCRVSG 161
Query: 612 WGYTGL--INYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYG 669
WG T +NY L+ A++ + +E+C Q + GK+T ++ +CAG ++ G CEGD G
Sbjct: 162 WGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKIT--DNMLCAGTKEGGKDSCEGDSG 219
Query: 670 GPLVCEQHKMRMVLGVIVPGR-GCAIPNRPGIFVRVAYYAKWIHKIILTYKVPQ 722
GPLVC R + G++ G C P+RPG++ RV+ Y WI + I Y+ Q
Sbjct: 220 GPLVCN----RTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRKYETQQ 269
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 119 bits (299), Expect = 8e-27
Identities = 77/228 (33%), Positives = 112/228 (49%), Gaps = 21/228 (9%)
Query: 502 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLK-DYEAWLGIHDVHGRGDEKCKQVL 560
W S+++R H+CGGSLI WVLTA CFP R L +Y LG + +
Sbjct: 50 WQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLS--V 107
Query: 561 NVSQLVYGPEGS------DLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGY 614
V +++ P+ S DL L++L RP L V + LP G P T C V GWG
Sbjct: 108 PVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGS 167
Query: 615 ----TGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESE-------ICAGAEKIGSGP 663
L + L V + ++ + C + + ++E +CAG +
Sbjct: 168 LRPGVPLPEWRPLQGV-RVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDA 226
Query: 664 CEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 711
C+GD GGPL C Q +++GV+ G+GCA+PNRPG++ VA Y+ WI
Sbjct: 227 CQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 119 bits (298), Expect = 1e-26
Identities = 77/258 (29%), Positives = 125/258 (48%), Gaps = 12/258 (4%)
Query: 465 EGDTTPTIVNLDHPVISCAKTKQLRVVNG-IPTRTNIGWMVSLRYRNKHICGGSLIKESW 523
EG + +V L + R+V G + + W SL+++ H+CGGS+I W
Sbjct: 192 EGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLW 251
Query: 524 VLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLM 577
++TA C DL ++W + D L V ++VY + G+D+ LM
Sbjct: 252 IITAAHCV--YDLYLPKSWTIQVGLVSLLDNPAPSHL-VEKIVYHSKYKPKRLGNDIALM 308
Query: 578 KLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYT--GLINYDGLLRVAHLYIMGNE 635
KLA P ++ + + LPN P+ C GWG T G + +L A + ++ N+
Sbjct: 309 KLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNK 368
Query: 636 KCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIP 695
C+ ++ S +CAG G C+GD GGPLVC++ ++ ++G G GCA
Sbjct: 369 ICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEV 428
Query: 696 NRPGIFVRVAYYAKWIHK 713
N+PG++ RV + WIH+
Sbjct: 429 NKPGVYTRVTSFLDWIHE 446
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 119 bits (297), Expect = 1e-26
Identities = 81/238 (34%), Positives = 121/238 (50%), Gaps = 28/238 (11%)
Query: 489 RVVNGIPTRTN-IGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHD 547
++V G N + + VSL H CGGSLI E WV++A C+ SR + LG H+
Sbjct: 23 KIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSR----IQVRLGEHN 77
Query: 548 VHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGCTI 601
+ E +Q +N ++++ P+ +D++L+KL+ AV++ VSTI LP T
Sbjct: 78 IEVL--EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLP----TA 131
Query: 602 PEK--TSCSVYGWGYTGL--INYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAE 657
P T C + GWG T +Y L+ ++ KC + GK+T N C G
Sbjct: 132 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSN--MFCVGFL 189
Query: 658 KIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
+ G C+GD GGP+VC + GV+ G GCA N+PG++ +V Y KWI I
Sbjct: 190 EGGKDSCQGDSGGPVVCN----GQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 243
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 117 bits (292), Expect = 5e-26
Identities = 78/252 (30%), Positives = 120/252 (47%), Gaps = 17/252 (6%)
Query: 481 SCAKTKQL-RVVNGIPTRTNIG-WMVSLRYRNKHICGGSLIKESWVLTARQCFPSR-DLK 537
+C + + L R+V G T+ W VS++ H CGGSLI E WVLTA CF + +
Sbjct: 25 ACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETS 84
Query: 538 DYEAWLGIHDVHGRGDE----KCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTID 593
Y+ LG + G + +QV + +D+ L++L P +++ +
Sbjct: 85 LYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVC 144
Query: 594 LPNYGCTIPEKTSCSVYGWGYTG---LINYDGLLRVAHLYIMGNEKCSQHHRGKV----- 645
LP+ +C V GWG L+ +L+ + I+ KC+ +
Sbjct: 145 LPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQ 204
Query: 646 --TLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVR 703
T+ +CAG E+ C+GD GGPLVC + + GVI G GCA NRPG+++R
Sbjct: 205 PKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIR 264
Query: 704 VAYYAKWIHKII 715
V + WIH+II
Sbjct: 265 VTAHHNWIHRII 276
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,305,904
Number of Sequences: 37866
Number of extensions: 1730000
Number of successful extensions: 3861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2845
Number of HSP's gapped (non-prelim): 336
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.