Guide to the Human Genome
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Search of human proteins with 57863314

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
         (355 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57863314 vacuolar protein sorting 37C [Homo sapiens]               739   0.0  
gi|13375926 vacuolar protein sorting 37B [Homo sapiens]               166   4e-41
gi|117938318 vacuolar protein sorting 37D [Homo sapiens]              131   8e-31
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     82   6e-16
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     82   6e-16
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    82   6e-16
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    82   6e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     81   2e-15
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    80   2e-15
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               80   2e-15
gi|223555921 hepatocellular carcinoma related protein 1 isoform ...    79   6e-15
gi|223555919 hepatocellular carcinoma related protein 1 isoform ...    79   6e-15
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    79   8e-15
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    79   8e-15
gi|160707881 formin 2 [Homo sapiens]                                   79   8e-15
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    77   3e-14
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         77   3e-14
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                76   4e-14
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    75   7e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni...    75   1e-13
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       74   2e-13
gi|118498339 EMI domain containing 2 [Homo sapiens]                    74   2e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    74   3e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    73   4e-13
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 73   4e-13
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...    73   4e-13
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    72   6e-13
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    72   1e-12
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r...    72   1e-12
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    71   1e-12

>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
          Length = 355

 Score =  739 bits (1907), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPL 60
           METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPL
Sbjct: 1   METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPL 60

Query: 61  EISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAE 120
           EISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAE
Sbjct: 61  EISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAE 120

Query: 121 KFLEGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVR 180
           KFLEGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVR
Sbjct: 121 KFLEGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVR 180

Query: 181 PVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGP 240
           PVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGP
Sbjct: 181 PVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGP 240

Query: 241 LGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQS 300
           LGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQS
Sbjct: 241 LGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQS 300

Query: 301 PYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWPGY 355
           PYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWPGY
Sbjct: 301 PYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWPGY 355


>gi|13375926 vacuolar protein sorting 37B [Homo sapiens]
          Length = 285

 Score =  166 bits (419), Expect = 4e-41
 Identities = 122/332 (36%), Positives = 171/332 (51%), Gaps = 66/332 (19%)

Query: 8   TLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNL 67
           +L +L EL  D   + ++  +  E Q++QL +EM LA+NRSLAE NL +Q  L+  ++ L
Sbjct: 14  SLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKARL 73

Query: 68  SDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEV 127
           + +YQEL+ L E  Q +K KL++ SS+    TLL LLQ EG KIEE++E MAEKFL+GE+
Sbjct: 74  TQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGEL 133

Query: 128 PLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVPQGTP 187
           PL++F++ + S R L+H+RRV++EKLQE+V K +            R P  + P+P   P
Sbjct: 134 PLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQ------------RLPQALAPLP---P 178

Query: 188 PVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPA 247
            + E  P  PL   PYP P +  P       A   +PP P PV       +G L   + A
Sbjct: 179 RLPELAPTAPL---PYPAPEASGPP----AVAPRRIPPPPPPVP------AGRLATPFTA 225

Query: 248 AQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQ--SPYPAT 305
           A            S  +++P    YPG       P  P R G     G+  Q  SPYP  
Sbjct: 226 AM-----------SSGQAVP----YPGLQC----PPLPPRVGLPTQQGFSSQFVSPYP-- 264

Query: 306 GGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPG 337
              PP P +P             P  PP+ PG
Sbjct: 265 ---PPLPQRPP------------PRLPPHQPG 281



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 8/47 (17%)

Query: 312 PIQPQLPSFPGQPQPSVPLQPPYPPGPAPPY----GFPPPPGPAWPG 354
           P+ P+LP       P+ PL  P P    PP       PPPP P   G
Sbjct: 175 PLPPRLPELA----PTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAG 217


>gi|117938318 vacuolar protein sorting 37D [Homo sapiens]
          Length = 251

 Score =  131 bits (330), Expect = 8e-31
 Identities = 88/229 (38%), Positives = 122/229 (53%), Gaps = 13/229 (5%)

Query: 11  ELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDR 70
           +L +L  D   +D++   S + Q LQLERE  LA+N +LA+ NL  +  LE+ R+ L+ +
Sbjct: 26  QLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRAALAIK 85

Query: 71  YQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLE 130
           YQELR++ E C ++  +LE+      P   L  LQ E  + E+E+E   E+ L GE  LE
Sbjct: 86  YQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLLGEQSLE 145

Query: 131 TFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELA--GDAPPPRPPPPVRPVPQGT-- 186
            FL  F   R L+HLRR + EKLQE++R+   S + A    A PP+  P    +P G   
Sbjct: 146 AFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAAR 205

Query: 187 -PPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQP 234
            PP V  +  PPL   P P P   SP  P+GP       P   P  SQP
Sbjct: 206 GPPAV-PRSLPPLDSRPVP-PLKGSPGCPLGPA------PLLSPRPSQP 246



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 9/77 (11%)

Query: 225 PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGY 284
           PAP      P         ++PAA + P GAA    +  RS+PP    P  P+  S PG 
Sbjct: 181 PAPTSAADPPK--------SFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGS-PGC 231

Query: 285 PLRGGRAPSPGYPQQSP 301
           PL      SP   Q  P
Sbjct: 232 PLGPAPLLSPRPSQPEP 248



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 18/62 (29%), Positives = 24/62 (38%), Gaps = 1/62 (1%)

Query: 292 PSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPA 351
           P   +P  +  P    + P  +   LP    +P P +   P  P GPAP    P P  P 
Sbjct: 189 PPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS-PRPSQPE 247

Query: 352 WP 353
            P
Sbjct: 248 PP 249



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 5/80 (6%)

Query: 263 QRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPG 322
           +RS  P P     P  +      L  G A  P    +S  P    +P     P L   PG
Sbjct: 176 ERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRS-LPPLDSRPV----PPLKGSPG 230

Query: 323 QPQPSVPLQPPYPPGPAPPY 342
            P    PL  P P  P PP+
Sbjct: 231 CPLGPAPLLSPRPSQPEPPH 250


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 108/378 (28%), Positives = 151/378 (39%), Gaps = 60/378 (15%)

Query: 9   LQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLS 68
           LQ L  ++ND EA        P+   L  E    +  +++ A+ + + +  L+I    L 
Sbjct: 405 LQHLLLVRNDYEA-------RPQYYKLIEECISQIVLHKNGADPDFKCRH-LQIEIEGLI 456

Query: 69  DRYQELRKLVERCQEQKAKLEK-FSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEV 127
           D+  +  K VE+ + + A+LEK   S L   T    LQVE  K+E + E   +     + 
Sbjct: 457 DQMIDKTK-VEKSEAKAAELEKKLDSEL---TARHELQVEMKKMESDFEQKLQDLQGEKD 512

Query: 128 PLETFLENFSSMRM-----LSHLRR--VRVEKLQEVVRKPRASQELAGDAPPPRPP---- 176
            L +  +  ++ +      +S L     ++ K  E  +K  AS   A    PP  P    
Sbjct: 513 ALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAP 572

Query: 177 -PPVRPVPQGTPPVVEEQPQP--PLAMPPYPLPYSPSPSLPVG------PTAHGALPPAP 227
            PP  P+P  +  ++   P P      PP P P  P P LP G      P+  G    +P
Sbjct: 573 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 632

Query: 228 FPVVSQPSFYSGPL----GPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283
            P +S  +    P     G   P+    P G A         +PP P  PG+      P 
Sbjct: 633 PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA---------IPPPPPLPGSAR-IPPPP 682

Query: 284 YPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSV----PLQPPYPPG-- 337
            PL G     P  P   P P   G PP P  P LP  PG P P      P  PP PPG  
Sbjct: 683 PPLPGSAGIPPPPP---PLPGEAGMPPPP--PPLPGGPGIPPPPPFPGGPGIPPPPPGMG 737

Query: 338 --PAPPYGFPPPPGPAWP 353
             P PP+GF  P  P  P
Sbjct: 738 MPPPPPFGFGVPAAPVLP 755


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 108/378 (28%), Positives = 151/378 (39%), Gaps = 60/378 (15%)

Query: 9   LQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLS 68
           LQ L  ++ND EA        P+   L  E    +  +++ A+ + + +  L+I    L 
Sbjct: 414 LQHLLLVRNDYEA-------RPQYYKLIEECISQIVLHKNGADPDFKCRH-LQIEIEGLI 465

Query: 69  DRYQELRKLVERCQEQKAKLEK-FSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEV 127
           D+  +  K VE+ + + A+LEK   S L   T    LQVE  K+E + E   +     + 
Sbjct: 466 DQMIDKTK-VEKSEAKAAELEKKLDSEL---TARHELQVEMKKMESDFEQKLQDLQGEKD 521

Query: 128 PLETFLENFSSMRM-----LSHLRR--VRVEKLQEVVRKPRASQELAGDAPPPRPP---- 176
            L +  +  ++ +      +S L     ++ K  E  +K  AS   A    PP  P    
Sbjct: 522 ALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAP 581

Query: 177 -PPVRPVPQGTPPVVEEQPQP--PLAMPPYPLPYSPSPSLPVG------PTAHGALPPAP 227
            PP  P+P  +  ++   P P      PP P P  P P LP G      P+  G    +P
Sbjct: 582 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 641

Query: 228 FPVVSQPSFYSGPL----GPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283
            P +S  +    P     G   P+    P G A         +PP P  PG+      P 
Sbjct: 642 PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA---------IPPPPPLPGSAR-IPPPP 691

Query: 284 YPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSV----PLQPPYPPG-- 337
            PL G     P  P   P P   G PP P  P LP  PG P P      P  PP PPG  
Sbjct: 692 PPLPGSAGIPPPPP---PLPGEAGMPPPP--PPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746

Query: 338 --PAPPYGFPPPPGPAWP 353
             P PP+GF  P  P  P
Sbjct: 747 MPPPPPFGFGVPAAPVLP 764


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 71/195 (36%), Positives = 73/195 (37%), Gaps = 51/195 (26%)

Query: 168 GDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPS---LP---VGPTAHG 221
           G A P  PPPP    P G  P     P+PPL  P  P P  P P    LP    GP   G
Sbjct: 219 GPAGPGGPPPPF---PAGQTP-----PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG 270

Query: 222 ALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASG 281
             PP P     QP F   PLGP  P    GP              PP PGY         
Sbjct: 271 DRPPPPVLFPGQP-FGQPPLGPLPP----GPP-------------PPVPGY--------- 303

Query: 282 PGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAP- 340
                  G  P P  PQQ P P  G  PP P  P  P     P P +P  PP  P PAP 
Sbjct: 304 -------GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPH 356

Query: 341 --PYGFPPPPGPAWP 353
             P  FPPP     P
Sbjct: 357 VNPAFFPPPTNSGMP 371



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 70/184 (38%), Positives = 74/184 (40%), Gaps = 38/184 (20%)

Query: 172 PPRPP--PPVRPVPQGTPPVVEEQPQPPLAMPP----YPLPYSPSPSLPVGPTAHGALPP 225
           PPRPP  PP  P P G PP  +  P PPLA PP     P P    P  P G    G LPP
Sbjct: 236 PPRPPLGPPGPPGPPGPPPPGQVLP-PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP 294

Query: 226 APFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPG-YPGTPMGASGPGY 284
            P P V     Y  P GP  P  Q GP              PP PG +P  P G  GP  
Sbjct: 295 GPPPPVPG---YGPPPGP--PPPQQGP--------------PPPPGPFPPRPPGPLGPPL 335

Query: 285 PLRGGRAPSPGYPQQSPYPATGGKPPYP-IQPQLPSFPGQPQPSVPLQPPYPPGPAPPYG 343
            L    AP    P   P P  G  PP P + P    FP      +P      P P  PYG
Sbjct: 336 TL----AP----PPHLPGPPPGAPPPAPHVNPAF--FPPPTNSGMPTSDSRGPPPTDPYG 385

Query: 344 FPPP 347
            PPP
Sbjct: 386 RPPP 389



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 53/148 (35%), Positives = 59/148 (39%), Gaps = 29/148 (19%)

Query: 208 SPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMP 267
           S   + P G    G  P A    V     + GP GP  P               P    P
Sbjct: 192 SSRAAFPQGGRGRGRFPGA----VPGGDRFPGPAGPGGPPPPF-----------PAGQTP 236

Query: 268 PRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQP--Q 325
           PRP  P  P G  GP  P   G+   P  P   P P  G +PP P+      FPGQP  Q
Sbjct: 237 PRP--PLGPPGPPGPPGPPPPGQVLPP--PLAGP-PNRGDRPPPPVL-----FPGQPFGQ 286

Query: 326 PSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
           P +   PP PP P P YG  PPPGP  P
Sbjct: 287 PPLGPLPPGPPPPVPGYG--PPPGPPPP 312



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 36/89 (40%), Positives = 39/89 (43%), Gaps = 21/89 (23%)

Query: 271 GYPGTPMGASGPGYPLRG-GRAPSPGYP---QQSPYPATGGKPPYPIQPQLPSFP-GQPQ 325
           G  G P G+S   +P  G GR   PG      + P PA  G PP       P FP GQ  
Sbjct: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-------PPFPAGQTP 236

Query: 326 PSVPLQPPYPPGPAPPYGFPPPPGPAWPG 354
           P  PL PP PPG         PPGP  PG
Sbjct: 237 PRPPLGPPGPPG---------PPGPPPPG 256


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 80/231 (34%), Positives = 90/231 (38%), Gaps = 41/231 (17%)

Query: 151 EKLQEVVRKPRASQELAGDAPPPRP--------PPPVRPVPQGTPPVVEEQPQ--PPLAM 200
           + L E V +  +   +AG+   P P        PPP    PQG PP    +PQ  PP   
Sbjct: 17  QNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 76

Query: 201 PPYPLPY-----SP--SPSLPVGPTAHGA------LPPAPFPVVSQPSFYSGPLGPTYPA 247
           P  P P      SP   P  P GP   G        PP   P    P   + P GP  P 
Sbjct: 77  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136

Query: 248 AQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGG 307
              GP      S SP RS P +P  P  P G + P      G  P PG PQ    P  GG
Sbjct: 137 KPQGPPPQGDKSRSP-RSPPGKPQGP-PPQGGNQP-----QGPPPPPGKPQGP--PPQGG 187

Query: 308 K----PPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAP-----PYGFPPPPG 349
           K    PP P +PQ P   G    S    P  P GP P     P G PPPPG
Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 79/238 (33%), Positives = 89/238 (37%), Gaps = 50/238 (21%)

Query: 156 VVRKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQ--PPLAMPPYPLPYSPS--- 210
           +   P+      G+ P   PPPP +P  QG PP    +PQ  PP   P  P P       
Sbjct: 32  IAGNPQGPSPQGGNKPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 89

Query: 211 ----PSLPVGPTAHGAL------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSW 260
               P  P GP   G        PP   P    P   + P GP  P    GP      S 
Sbjct: 90  PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSR 149

Query: 261 SPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGK----PPYPIQPQ 316
           SP RS P +P  P  P G + P  P      P PG PQ  P    GGK    PP P +PQ
Sbjct: 150 SP-RSPPGKPQGP-PPQGGNQPQGP-----PPPPGKPQGPP--PQGGKKPQGPPPPGKPQ 200

Query: 317 LP-----------SFPGQPQ---------PSVPLQPPYPPGPAPPYGFPPPPGPAWPG 354
            P           S PG+PQ         P  P  PP  P   PP G   P GP  PG
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258



 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 64/200 (32%), Positives = 78/200 (39%), Gaps = 20/200 (10%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPT 218
           KP+      G+ P   PPPP +P  QG PP    +PQ P   PP   P  P P    G  
Sbjct: 96  KPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNRPQGP---PPPGKPQGPPPQ---GDK 147

Query: 219 AHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMG 278
           +     P   P    P   + P GP  P  +  P+G         +  PP    PG P G
Sbjct: 148 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGKKPQGPPP----PGKPQG 201

Query: 279 ASGPGYPLRGGRAPSPGYPQQSPYPATG----GKPPYPIQPQLPSFPGQPQPSVPLQPPY 334
               G   R  ++P PG PQ  P P  G    G PP P +PQ P   G  +P  P  P  
Sbjct: 202 PPPQGDKSRSSQSP-PGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259

Query: 335 PPGPAPPYGFPPPPGPAWPG 354
           P GP    G       + PG
Sbjct: 260 PQGPPAQGGSKSQSARSPPG 279



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 57/177 (32%), Positives = 67/177 (37%), Gaps = 23/177 (12%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQ--PPLAMPPYPLPYSPS------ 210
           KP+      G+ P   PPPP +P  QG PP   ++PQ  PP   P  P P          
Sbjct: 157 KPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQS 214

Query: 211 -PSLPVGPTAHGAL------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQ 263
            P  P GP   G        PP   P    P   + P GP  P    GP    G      
Sbjct: 215 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSA 274

Query: 264 RSMPPRPGYPGTPMGASGPGYPLRGG------RAPSPGYPQQSPYPATGGKPPYPIQ 314
           RS P +P  P    G +  G P   G      +AP  G PQ  P P  GG+P  P Q
Sbjct: 275 RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 77/235 (32%), Positives = 86/235 (36%), Gaps = 48/235 (20%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQ--PPLAMPPYPLPYSPS------ 210
           KP+      G+ P   PPPP +P  QG PP    +PQ  PP   P  P P          
Sbjct: 56  KPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 113

Query: 211 -PSLPVGPTAHGAL------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQ 263
            P  P GP   G        PP   P    P   + P GP  P    GP           
Sbjct: 114 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSS 173

Query: 264 RSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKP---PYPIQPQLP-- 318
           RS P +P  P  P G + P  P      P PG PQ  P P  G KP   P P +PQ P  
Sbjct: 174 RSPPGKPQGP-PPQGGNQPQGP-----PPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPP 226

Query: 319 ----------SFPGQPQ---------PSVPLQPPYPPGPAPPYGFPPPPGPAWPG 354
                     S PG+PQ         P  P  PP  P   PP G   P GP  PG
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 77/236 (32%), Positives = 87/236 (36%), Gaps = 49/236 (20%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQ--PPLAMPPYPLPYSPS------ 210
           KP+      G+ P   PPPP +P  QG PP    +PQ  PP   P  P P   +      
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSR 174

Query: 211 --PSLPVGPTAHGAL------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSP 262
             P  P GP   G        PP   P    P   + P GP  P    GP          
Sbjct: 175 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234

Query: 263 QRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKP---PYPIQPQLP- 318
            RS P +P  P  P G + P  P      P PG PQ  P P  G KP   P P +PQ P 
Sbjct: 235 ARSPPGKPQGP-PPQGGNQPQGP-----PPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPP 287

Query: 319 -----------SFPGQPQ---------PSVPLQPPYPPGPAPPYGFPPPPGPAWPG 354
                      S PG+PQ         P  P  PP  P   PP G   P GP  PG
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 79/240 (32%), Positives = 90/240 (37%), Gaps = 53/240 (22%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQ--PPLAMPPYPLPYSPS------ 210
           KP+      G+ P   PPPP +P  QG PP    +PQ  PP   P  P P   +      
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR 236

Query: 211 --PSLPVGPTAHGAL------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSP 262
             P  P GP   G        PP   P    P   + P GP  P    GP    G     
Sbjct: 237 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296

Query: 263 QRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKP---PYPIQPQLP- 318
            RS P +P  P  P G + P  P      P PG PQ  P P  G KP   P P +PQ P 
Sbjct: 297 SRSPPGKPQGP-PPQGGNQPQGP-----PPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPP 349

Query: 319 -----------SFPGQPQP------SVPLQPPYPPG------PAPPYGFPP-PPGPAWPG 354
                      S PG+PQ       + P  PP P G       APP G P  PP P   G
Sbjct: 350 PQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 409



 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 72/217 (33%), Positives = 82/217 (37%), Gaps = 36/217 (16%)

Query: 162 ASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHG 221
           ++Q L  D      P  +   PQG PP    +PQ P + P  P      P    G    G
Sbjct: 15  SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKP----QGPPPQGGNQPQG 70

Query: 222 ALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASG 281
             PP   P    P   + P GP  P    GP      S SP RS P +P  P  P G + 
Sbjct: 71  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP-RSPPGKPQGP-PPQGGNQ 128

Query: 282 PGYPLRGGRAPSPGYPQQSPYPATGGKP---PYPIQPQLP------------SFPGQPQ- 325
           P  P      P PG PQ  P P  G KP   P P +PQ P            S PG+PQ 
Sbjct: 129 PQGP-----PPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182

Query: 326 --------PSVPLQPPYPPGPAPPYGFPPPPGPAWPG 354
                   P  P  PP  P   PP G   P GP  PG
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 58/178 (32%), Positives = 67/178 (37%), Gaps = 24/178 (13%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQ--PPLAMPPYPLPYSPS------ 210
           KP+      G+ P   PPPP +P  QG PP    +PQ  PP   P  P P   S      
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298

Query: 211 --PSLPVGPTAHGAL------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSP 262
             P  P GP   G        PP   P    P   + P GP  P    GP    G     
Sbjct: 299 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 358

Query: 263 QRSMPPRPGYPGTPMGASGPGYPLRGG------RAPSPGYPQQSPYPATGGKPPYPIQ 314
            RS P +P  P    G +  G P   G      +AP  G PQ  P P  GG+P  P Q
Sbjct: 359 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 65/178 (36%), Positives = 69/178 (38%), Gaps = 17/178 (9%)

Query: 171 PPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPV 230
           PPPRP  P  P PQG      + P P    P  P P   + S   GP  H   P  P P 
Sbjct: 134 PPPRPGKPEGPPPQGGNQ--SQGPPPRPGKPEGPPPQGGNQSQ--GPPPHPGKPEGPPPQ 189

Query: 231 VSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGR 290
               S   GP  P  P    GP    G   +  +  PPRPG P  P    G       G 
Sbjct: 190 GGNQS--QGP--PPRPGKPEGPPPQGG---NQSQGPPPRPGKPEGPPSQGGNKPQ---GP 239

Query: 291 APSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPP 348
            P PG PQ  P P  G KP  P  P  P   G P P    Q P PP    P G PPPP
Sbjct: 240 PPHPGKPQGPP-PQEGNKPQRPPPPGRPQ--GPPPPGGNPQQPLPPPAGKPQGPPPPP 294



 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 65/198 (32%), Positives = 75/198 (37%), Gaps = 20/198 (10%)

Query: 159 KPRASQELAGD---APPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPV 215
           KP       G+    PPPRP  P  P PQG      + P P    P  P P   + S   
Sbjct: 98  KPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQ--SQGPPPRPGKPEGPPPQGGNQSQ-- 153

Query: 216 GPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGT 275
           GP      P  P P     S   GP  P +P    GP    G   +  +  PPRPG P  
Sbjct: 154 GPPPRPGKPEGPPPQGGNQS--QGP--PPHPGKPEGPPPQGG---NQSQGPPPRPGKPEG 206

Query: 276 PMGASGPGYPLRGGRAPSPGYPQQSPYPATG---GKPPYPIQPQLPSFPGQPQPSVPLQP 332
           P    G       G  P PG P+  P        G PP+P +PQ P      +P  P  P
Sbjct: 207 PPPQGGNQSQ---GPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPP 263

Query: 333 PYPPGPAPPYGFPPPPGP 350
             P GP PP G P  P P
Sbjct: 264 GRPQGPPPPGGNPQQPLP 281



 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 72/245 (29%), Positives = 85/245 (34%), Gaps = 60/245 (24%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMP----------------P 202
           KP   +   G+ P   PPPP +P  +G PP    Q Q P   P                P
Sbjct: 35  KPEGRRPQGGNQPQRTPPPPGKP--EGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 92

Query: 203 YPLPYSPSPSLPVGPTAHGALPPAPF-PVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWS 261
            P P  P    P G       PP P  P    P   +   GP  P     P G      +
Sbjct: 93  PPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP--PPRPGKPEGPPPQGGN 150

Query: 262 PQRSMPPRPG------------------YPGTPMGASGPGYPLRGGRAPSPGYPQQSPYP 303
             +  PPRPG                  +PG P G    G     G  P PG P+  P P
Sbjct: 151 QSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP-P 209

Query: 304 ATG----GKPPYPIQPQ------------LPSFPGQPQPSVPLQ---PPYPPGPAPPYGF 344
             G    G PP P +P+             P  PG+PQ   P +   P  PP P  P G 
Sbjct: 210 QGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQG- 268

Query: 345 PPPPG 349
           PPPPG
Sbjct: 269 PPPPG 273



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 54/161 (33%), Positives = 61/161 (37%), Gaps = 20/161 (12%)

Query: 171 PPPRPPPPVRPVPQGT-----PPVVEEQPQPP------LAMPPYPLPYSPSPSLPVGPTA 219
           PPPRP  P  P PQG      PP    +P+ P       +  P P P  P    P G   
Sbjct: 155 PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214

Query: 220 HGALPPAPFPVVSQPSFYSG-PLGPT-YPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPM 277
               PP P      PS     P GP  +P    GP    G       + P RP  PG P 
Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEG-------NKPQRPPPPGRPQ 267

Query: 278 GASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLP 318
           G   PG   +    P  G PQ  P P  GG+P  P Q Q P
Sbjct: 268 GPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 13/100 (13%)

Query: 262 PQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATG----GKPPYPIQPQ- 316
           PQR+ PP    PG P G    G     G  P PG P+  P P  G    G PP P +P+ 
Sbjct: 47  PQRTPPP----PGKPEGRPPQGGNQSQGPPPRPGKPEGPP-PQGGNQSQGPPPRPGKPEG 101

Query: 317 LPSFPGQPQPSVPLQPPYPPGPAPPYGFP---PPPGPAWP 353
            P   G      P +P  P GP P  G     PPP P  P
Sbjct: 102 QPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 141



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 38/110 (34%), Positives = 44/110 (40%), Gaps = 12/110 (10%)

Query: 252 PRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATG----G 307
           P G      +  +  PPRPG P  P    G       G  P PG P+  P P  G    G
Sbjct: 57  PEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ---GPPPRPGKPEGQP-PQGGNQSQG 112

Query: 308 KPPYPIQPQLPSFPGQPQPS-VPLQPPYPPGPAPPYGFP---PPPGPAWP 353
            PP P +P+ P   G  Q    P +P  P GP P  G     PPP P  P
Sbjct: 113 PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 162



 Score = 28.5 bits (62), Expect = 9.6
 Identities = 13/44 (29%), Positives = 18/44 (40%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPP 202
           +P+      G+   P PPP  +P     PP      +PP   PP
Sbjct: 265 RPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 81/228 (35%), Positives = 93/228 (40%), Gaps = 37/228 (16%)

Query: 157 VRKPRASQEL-AGDAPPPRPPPPVRPVPQGTPPVVEEQPQPP---LAMPPYPLPYSPSPS 212
           + KP A   L AG     RPPPP+       PP+ E  P PP   L +PP P P  P+PS
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMP-PTGPAPS 272

Query: 213 LPVG-----PTAHGALPPAPFPVVSQPSFYSGPLGP-TYPAAQLGPRGAAGYSWSPQRSM 266
            P G     P A G  PPA  PVV  P+    P  P  +P A      A G         
Sbjct: 273 GPPGPPQLPPPAPGVHPPA--PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH 330

Query: 267 PPRPGY----PGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYP--------IQ 314
           PP PG     PG    A G   P  G   P+PG     P P+ G  P  P        + 
Sbjct: 331 PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV---HPPPSAGVHPQAPGVHPAAPAVH 387

Query: 315 PQLPSF----PGQPQPSVPLQPPYPPG--PAPPYGFPPPPG--PAWPG 354
           PQ P      PG   P  P   P PPG  P+ P   P PPG  P+ PG
Sbjct: 388 PQAPGVHPPAPGM-HPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPG 434



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 61/173 (35%), Positives = 71/173 (41%), Gaps = 24/173 (13%)

Query: 170 APPPRPPPPV--RPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAP 227
           AP   PP P    P P   PP     P  P   PP P  + P+P   V P A G  PPAP
Sbjct: 305 APGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPG--VHPPAPGVHPPAP 362

Query: 228 FPVVSQPSFYSGPLGP-TYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG-YP 285
             V   PS    P  P  +PAA      A G         PP PG     M    PG +P
Sbjct: 363 -GVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVH-------PPAPG-----MHPQAPGVHP 409

Query: 286 LRGGRAPS-PGYPQQSP--YPATGG-KPPYPIQPQL-PSFPGQPQPSVPLQPP 333
              G  PS PG   Q P  +P+  G  PP P+ P L P  P +   ++P  PP
Sbjct: 410 QPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462


>gi|223555921 hepatocellular carcinoma related protein 1 isoform 2
           [Homo sapiens]
          Length = 372

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 40/154 (25%), Positives = 83/154 (53%)

Query: 4   LKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEIS 63
           L + ++ +L ++    E + +  L  P+++ +  +++  + +   LA +NL  +  LE  
Sbjct: 209 LSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAK 268

Query: 64  RSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFL 123
           R  + D+Y+ L ++    +++  +  + S +     L   L+V   + EEES+ +AE FL
Sbjct: 269 RQTVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFL 328

Query: 124 EGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVV 157
           EG++ ++ FL +F   R + H RR + EKLQ+ +
Sbjct: 329 EGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAI 362


>gi|223555919 hepatocellular carcinoma related protein 1 isoform 1
           [Homo sapiens]
          Length = 397

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 40/154 (25%), Positives = 83/154 (53%)

Query: 4   LKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEIS 63
           L + ++ +L ++    E + +  L  P+++ +  +++  + +   LA +NL  +  LE  
Sbjct: 234 LSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAK 293

Query: 64  RSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFL 123
           R  + D+Y+ L ++    +++  +  + S +     L   L+V   + EEES+ +AE FL
Sbjct: 294 RQTVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFL 353

Query: 124 EGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVV 157
           EG++ ++ FL +F   R + H RR + EKLQ+ +
Sbjct: 354 EGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAI 387


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 80/268 (29%), Positives = 94/268 (35%), Gaps = 90/268 (33%)

Query: 171 PPPRP---------PPPVRPVPQ---------GTPPVV--EEQPQPPLAMPPYP------ 204
           PPPRP         PPPV   P+         G+PPV     QP P    PP+P      
Sbjct: 170 PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229

Query: 205 --------------LPYSPSPSLPVGPTAHGAL----PPAPFPVVSQPSFYSGPLGP--- 243
                          P+S  P LP  PT   AL    PP P PV ++PS +   + P   
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLP--PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287

Query: 244 --TYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASG------------------PG 283
               P     PR +A     P    P RPG P  P  +SG                  P 
Sbjct: 288 QNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP 347

Query: 284 YPLRGGRAPSPGYPQQSPYPA-------TGGKPP-------------YPIQPQLPSFPGQ 323
            P  G   P P  P + P P        +G  PP              P  PQLPS  G 
Sbjct: 348 LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407

Query: 324 PQPSVPLQPPYPPGPAPPYGFPPPPGPA 351
             P    +PP PP   P  G PPPP P+
Sbjct: 408 DSPRSGPRPPLPP-DRPSAGAPPPPPPS 434



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 64/187 (34%), Positives = 75/187 (40%), Gaps = 25/187 (13%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPS-PSLPVGPT 218
           P   +  A    PP PPPP RP P   PP      + P  +P   L  S S P LP  P 
Sbjct: 295 PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP-RLPQRNLSLSSSTPPLP-SPG 352

Query: 219 AHGALPPAPF----PVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYP- 273
             G LPP P     P V  P   SGPL P  P ++ G         S  R++P  P  P 
Sbjct: 353 RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG---------STSRALPATPQLPS 403

Query: 274 --GTPMGASGPGYPLRGGRAPSPGYPQQSPYPAT---GGKPPYPIQPQLPS-FPGQPQPS 327
             G     SGP  PL   R PS G P   P P+T    G    P + +  S F   P   
Sbjct: 404 RSGVDSPRSGPRPPLPPDR-PSAGAPPPPP-PSTSIRNGFQDSPCEDEWESRFYFHPISD 461

Query: 328 VPLQPPY 334
           +P   PY
Sbjct: 462 LPPPEPY 468



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 63/202 (31%), Positives = 75/202 (37%), Gaps = 19/202 (9%)

Query: 159 KPRASQELAGDAPPPRP---PPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPV 215
           KP +     G  P P P     P  P     PP   +    P ++PP P+P +P P +  
Sbjct: 139 KPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP-PVPSTPRP-IQS 196

Query: 216 GPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPP---RPGY 272
            P   G+ P    P   QPS   GP  P +P  +    G      SP  S  P   RP  
Sbjct: 197 SPHNRGSPPVPGGP--RQPS--PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPL 252

Query: 273 PGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQP 332
           P TP  A     P      P P      P       PP P Q   P  P  P+PS   Q 
Sbjct: 253 PPTPSRALDDKPP------PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306

Query: 333 PYPPGPAPPYGFPPPPGPAWPG 354
           P PP P P    PPP  P+  G
Sbjct: 307 P-PPPPPPSRPGPPPLPPSSSG 327



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 48/143 (33%), Positives = 55/143 (38%), Gaps = 18/143 (12%)

Query: 216 GPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPG-YP- 273
           GP   G L  A  P +   +      G + P   L P G    S  P  S P  PG +P 
Sbjct: 96  GPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP--LLPPGGRSTSAKPF-SPPSGPGRFPV 152

Query: 274 GTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPG--QPQPSVPLQ 331
            +P   SGP  P R    P        P P  G KP   I P +PS P   Q  P     
Sbjct: 153 PSPGHRSGPPEPQRNRMPP--------PRPDVGSKPD-SIPPPVPSTPRPIQSSPHNRGS 203

Query: 332 PPYPPGPAPPYGFPPPPGPAWPG 354
           PP P GP  P   P P  P +PG
Sbjct: 204 PPVPGGPRQPS--PGPTPPPFPG 224


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 80/268 (29%), Positives = 94/268 (35%), Gaps = 90/268 (33%)

Query: 171 PPPRP---------PPPVRPVPQ---------GTPPVV--EEQPQPPLAMPPYP------ 204
           PPPRP         PPPV   P+         G+PPV     QP P    PP+P      
Sbjct: 170 PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229

Query: 205 --------------LPYSPSPSLPVGPTAHGAL----PPAPFPVVSQPSFYSGPLGP--- 243
                          P+S  P LP  PT   AL    PP P PV ++PS +   + P   
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLP--PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287

Query: 244 --TYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASG------------------PG 283
               P     PR +A     P    P RPG P  P  +SG                  P 
Sbjct: 288 QNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP 347

Query: 284 YPLRGGRAPSPGYPQQSPYPA-------TGGKPP-------------YPIQPQLPSFPGQ 323
            P  G   P P  P + P P        +G  PP              P  PQLPS  G 
Sbjct: 348 LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407

Query: 324 PQPSVPLQPPYPPGPAPPYGFPPPPGPA 351
             P    +PP PP   P  G PPPP P+
Sbjct: 408 DSPRSGPRPPLPP-DRPSAGAPPPPPPS 434



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 64/187 (34%), Positives = 75/187 (40%), Gaps = 25/187 (13%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPS-PSLPVGPT 218
           P   +  A    PP PPPP RP P   PP      + P  +P   L  S S P LP  P 
Sbjct: 295 PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP-RLPQRNLSLSSSTPPLP-SPG 352

Query: 219 AHGALPPAPF----PVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYP- 273
             G LPP P     P V  P   SGPL P  P ++ G         S  R++P  P  P 
Sbjct: 353 RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG---------STSRALPATPQLPS 403

Query: 274 --GTPMGASGPGYPLRGGRAPSPGYPQQSPYPAT---GGKPPYPIQPQLPS-FPGQPQPS 327
             G     SGP  PL   R PS G P   P P+T    G    P + +  S F   P   
Sbjct: 404 RSGVDSPRSGPRPPLPPDR-PSAGAPPPPP-PSTSIRNGFQDSPCEDEWESRFYFHPISD 461

Query: 328 VPLQPPY 334
           +P   PY
Sbjct: 462 LPPPEPY 468



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 63/202 (31%), Positives = 75/202 (37%), Gaps = 19/202 (9%)

Query: 159 KPRASQELAGDAPPPRP---PPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPV 215
           KP +     G  P P P     P  P     PP   +    P ++PP P+P +P P +  
Sbjct: 139 KPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP-PVPSTPRP-IQS 196

Query: 216 GPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPP---RPGY 272
            P   G+ P    P   QPS   GP  P +P  +    G      SP  S  P   RP  
Sbjct: 197 SPHNRGSPPVPGGP--RQPS--PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPL 252

Query: 273 PGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQP 332
           P TP  A     P      P P      P       PP P Q   P  P  P+PS   Q 
Sbjct: 253 PPTPSRALDDKPP------PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306

Query: 333 PYPPGPAPPYGFPPPPGPAWPG 354
           P PP P P    PPP  P+  G
Sbjct: 307 P-PPPPPPSRPGPPPLPPSSSG 327



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 48/143 (33%), Positives = 55/143 (38%), Gaps = 18/143 (12%)

Query: 216 GPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPG-YP- 273
           GP   G L  A  P +   +      G + P   L P G    S  P  S P  PG +P 
Sbjct: 96  GPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP--LLPPGGRSTSAKPF-SPPSGPGRFPV 152

Query: 274 GTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPG--QPQPSVPLQ 331
            +P   SGP  P R    P        P P  G KP   I P +PS P   Q  P     
Sbjct: 153 PSPGHRSGPPEPQRNRMPP--------PRPDVGSKPD-SIPPPVPSTPRPIQSSPHNRGS 203

Query: 332 PPYPPGPAPPYGFPPPPGPAWPG 354
           PP P GP  P   P P  P +PG
Sbjct: 204 PPVPGGPRQPS--PGPTPPPFPG 224


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 70/201 (34%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 166  LAGDAPPPRPPPPVRPVPQGTP-PVVEEQPQPPLA----MPPYPLPYSPSPSLPVGPTAH 220
            L G A PP PP P   +P   P P     P PPL      PP PLP +  P  P  P A 
Sbjct: 948  LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA- 1006

Query: 221  GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGAS 280
            G  PP P P    P        P  P A + P         P   +PP P  PG  +   
Sbjct: 1007 GIPPPPPLPGAGIPP------PPPLPGAGIPPPPPL-----PGAGIPPPPPLPGAGIP-- 1053

Query: 281  GPGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQ----PQLPSFPG---QPQPS 327
             P  PL G   P P      G P   P P  G  PP P+     P  P  PG    P P 
Sbjct: 1054 -PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112

Query: 328  VPLQPPYPPGPAPPYGFPPPP 348
            +P     PP P P  G PPPP
Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPP 1133



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 70/207 (33%), Positives = 75/207 (36%), Gaps = 35/207 (16%)

Query: 166  LAGDAPPPRPPPPVRPVPQGTP-PVVEEQPQPPLA----MPPYPLPYSPSPSLPVGPTAH 220
            L G   PP PP P   +P   P P     P PPL      PP PLP +  P  P  P A 
Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA- 1094

Query: 221  GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGT----- 275
            G  PP P P V  P        P  P A + P         P   +PP P  PG      
Sbjct: 1095 GIPPPPPLPGVGIPP------PPPLPGAGIPPPPPL-----PGAGIPPPPPLPGAGIPPP 1143

Query: 276  ---PMGASGPGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQPQLPSFPGQPQP 326
               P     P  PL G   P P      G P   P P  G  PP    P LP     P P
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP----PPLPGVGIPPPP 1199

Query: 327  SVPLQPPYPPGPAPPYGFPPPPGPAWP 353
             +P     PP P P  G PP P P  P
Sbjct: 1200 PLPGAGIPPPPPLPGMGIPPAPAPPLP 1226



 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 74/224 (33%), Positives = 83/224 (37%), Gaps = 51/224 (22%)

Query: 168  GDAPPPRPPPPVRPVPQGTPPVVEEQPQPP-------LAMPPYPLPYSPSPSLPVGPTAH 220
            G  PPP PP P   VP      +   PQPP       L  PP PLP +  P  P  P A 
Sbjct: 874  GMVPPPPPPLPGMTVPTLPSTAI---PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAG 930

Query: 221  ----------GALPPAPFP--VVSQPSFYSG---PLGPTYPAAQLGPRGAAGYSWSPQRS 265
                      G  PP P P   +  P    G   PL P  P A + P         P   
Sbjct: 931  ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL-----PGAG 985

Query: 266  MPPRPGYPGT------PMGASG--PGYPLRGGRAPSP------GYPQQSPYPATGGKPPY 311
            +PP P  PG       P+  +G  P  PL G   P P      G P   P P  G  PP 
Sbjct: 986  IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1045

Query: 312  PIQ----PQLPSFPG---QPQPSVPLQPPYPPGPAPPYGFPPPP 348
            P+     P  P  PG    P P +P     PP P P  G PPPP
Sbjct: 1046 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089



 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 69/201 (34%), Positives = 76/201 (37%), Gaps = 33/201 (16%)

Query: 166  LAGDAPPPRPPPPVRPVPQGTP-PVVEEQPQPPLA----MPPYPLPYSPSPSLPVGPTAH 220
            L G   PP PP P   +P   P P     P PPL      PP PLP +  P  P  P A 
Sbjct: 1003 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA- 1061

Query: 221  GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGAS 280
            G  PP P P    P        P  P A + P         P   +PP P  PG  +   
Sbjct: 1062 GIPPPPPLPGAGIPP------PPPLPGAGIPPPPPL-----PGAGIPPPPPLPGVGIP-- 1108

Query: 281  GPGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQ----PQLPSFPGQ---PQPS 327
             P  PL G   P P      G P   P P  G  PP P+     P  P  PG    P P 
Sbjct: 1109 -PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167

Query: 328  VPLQPPYPPGPAPPYGFPPPP 348
            +P     PP P P  G PPPP
Sbjct: 1168 LPGAGIPPPPPLPGVGIPPPP 1188



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 70/204 (34%), Positives = 77/204 (37%), Gaps = 27/204 (13%)

Query: 171  PPPRPPPPVRPVPQGTP-PVVEEQPQPPLA----MPPYPLPYSPSPSLPVGPTAHGALPP 225
            PPP PP P   +P   P P     P PPL      PP PLP +  P  P  P A   LPP
Sbjct: 909  PPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968

Query: 226  APFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGT------PMGA 279
             P P    P     P     P   L   G       P   +PP P  PG       P+  
Sbjct: 969  -PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027

Query: 280  SG--PGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQ----PQLPSFPG---QP 324
            +G  P  PL G   P P      G P   P P  G  PP P+     P  P  PG    P
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087

Query: 325  QPSVPLQPPYPPGPAPPYGFPPPP 348
             P +P     PP P P  G PPPP
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPP 1111



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 74/217 (34%), Positives = 81/217 (37%), Gaps = 36/217 (16%)

Query: 167  AGDAPPPR------PPPPVRP---VPQGTP-PVVEEQPQPPL----AMPPYPLPYSPSPS 212
            AG  PPP       PPPP  P   +P   P P     P PPL      PP PLP +  P 
Sbjct: 940  AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 999

Query: 213  LPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGY 272
             P  P A G  PP P P    P     P     P   L   G       P   +PP P  
Sbjct: 1000 PPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058

Query: 273  PGT------PMGASG--PGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQ---- 314
            PG       P+  +G  P  PL G   P P      G P   P P  G  PP P+     
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118

Query: 315  PQLPSFPG---QPQPSVPLQPPYPPGPAPPYGFPPPP 348
            P  P  PG    P P +P     PP P P  G PPPP
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 74/224 (33%), Positives = 82/224 (36%), Gaps = 47/224 (20%)

Query: 166  LAGDAPPPRPPPPVRPVPQGTP-PVVEEQPQPPLA----MPPYPLPYSPSPSLPVGPTAH 220
            L G   PP PP P   +P   P P     P PPL      PP PLP +  P  P  P A 
Sbjct: 970  LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA- 1028

Query: 221  GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGT----- 275
            G  PP P P    P        P  P A + P         P   +PP P  PG      
Sbjct: 1029 GIPPPPPLPGAGIPP------PPPLPGAGIPPPPPL-----PGAGIPPPPPLPGAGIPPP 1077

Query: 276  -PMGASG--PGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQ----PQLPSFPG 322
             P+  +G  P  PL G   P P      G P   P P  G  PP P+     P  P  PG
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1137

Query: 323  Q---PQPSVPLQPPYPPGPAPPYGFPPPP---------GPAWPG 354
                P P +P     PP P P  G PPPP          P  PG
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1181



 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/218 (32%), Positives = 81/218 (37%), Gaps = 36/218 (16%)

Query: 162  ASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPL---AMPPYPLPYSPSPSLPVGPT 218
            +S  + G    P PPPP+  +   T P       PPL    M P P P  P   +P  P 
Sbjct: 866  SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925

Query: 219  AHGA----LPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQ---RSMPPRPG 271
              GA    LPP P   +  P    G   P  P     P   AG    P      +PP P 
Sbjct: 926  LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPP-----PLPGAGIPLPPPLPGAGIPPPPP 980

Query: 272  YPGT------PMGASG--PGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQ--- 314
             PG       P+  +G  P  PL G   P P      G P   P P  G  PP P+    
Sbjct: 981  LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040

Query: 315  -PQLPSFPG---QPQPSVPLQPPYPPGPAPPYGFPPPP 348
             P  P  PG    P P +P     PP P P  G PPPP
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 62/191 (32%), Positives = 73/191 (38%), Gaps = 27/191 (14%)

Query: 173  PRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGA--LPPAPFPV 230
            P PPP        + P +   P PP  +P   +P  PS ++P  P   G   LPP P P+
Sbjct: 856  PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915

Query: 231  VSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGR 290
                     P  P  P A + P         P   +PP P  PG    A  P  PL G  
Sbjct: 916  PGAGI----PPPPPLPGAGILPLPPL-----PGAGIPPPPPLPGA---AIPPPPPLPGAG 963

Query: 291  APSP------GYPQQSPYPATGGKPPYPIQ----PQLPSFPGQ---PQPSVPLQPPYPPG 337
             P P      G P   P P  G  PP P+     P  P  PG    P P +P     PP 
Sbjct: 964  IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023

Query: 338  PAPPYGFPPPP 348
            P P  G PPPP
Sbjct: 1024 PLPGAGIPPPP 1034



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 69/202 (34%), Positives = 76/202 (37%), Gaps = 36/202 (17%)

Query: 166  LAGDAPPPRPPPPVRPVPQGTP-PVVEEQPQPPLA----MPPYPLPYSPSPSLPVGPTAH 220
            L G   PP PP P   +P   P P     P PPL      PP PLP    P  P  P A 
Sbjct: 1058 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA- 1116

Query: 221  GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGAS 280
            G  PP P P    P        P  P A + P         P+  +PP P  PG  +   
Sbjct: 1117 GIPPPPPLPGAGIPP------PPPLPGAGIPPPPPL-----PRVGIPPPPPLPGAGIP-- 1163

Query: 281  GPGYPLRGGRAPSP------GYPQQSPYPATGGKPPYPIQ----PQLPSFPGQ---PQPS 327
             P  PL G   P P      G P   P P  G  PP P+     P  P  PG    P P+
Sbjct: 1164 -PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA 1222

Query: 328  VPLQPP---YPPGPAPPYGFPP 346
             PL PP    PP P  P   PP
Sbjct: 1223 PPLPPPGTGIPPPPLLPVSGPP 1244



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 51/221 (23%), Positives = 76/221 (34%), Gaps = 27/221 (12%)

Query: 137 SSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVP------------- 183
           S ++    L++ + ++LQ  +++ +  Q+L G   P  PP  V P P             
Sbjct: 197 SDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGP 256

Query: 184 ---QGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALP--PAPFPVVSQPSFYS 238
               G  P   +  Q   A+   P   +  P  P  P + G LP   AP    +QP+   
Sbjct: 257 SGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKD 316

Query: 239 GPLGPTYPAAQLGP----RGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSP 294
            P    +P  + GP     GA                +   P G+ G  +    G     
Sbjct: 317 SPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQ 376

Query: 295 GYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYP 335
              ++    A G     P  P   S PG P PS     PYP
Sbjct: 377 RLGEEPEEEAQG-----PDAPAAASLPGSPAPSQRCFKPYP 412



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 55/212 (25%), Positives = 66/212 (31%), Gaps = 37/212 (17%)

Query: 169 DAPPPRPPPPVRPVPQGTPPVVEEQPQPP------LAMPPYPLPYSPSPSLPVGPTAHGA 222
           D  P RPP          PP  E  PQ        L + P  +        P    +   
Sbjct: 761 DGLPGRPP---------CPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811

Query: 223 LPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGP 282
            PP+      Q    S P        Q     +   ++    ++P  P  P T   +S P
Sbjct: 812 PPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMP 871

Query: 283 GY--------PLRGGRAP---SPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQ 331
           G         PL G   P   S   PQ  P   T   PP P  P LP     P P +P  
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP--PPLPGAGIPPPPPLPGA 929

Query: 332 PPYPPGPAPPYGFPPPP---------GPAWPG 354
              P  P P  G PPPP          P  PG
Sbjct: 930 GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG 961



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 36/122 (29%), Positives = 44/122 (36%), Gaps = 23/122 (18%)

Query: 168  GDAPPPRPP----PPVRPVP-QGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGA 222
            G  PPP  P    PP  P+P  G PP     P P + +PP P P  P P           
Sbjct: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPP---PPPLPGMGIPPAPAPPLPPPGT--------G 1231

Query: 223  LPPAPFPVVSQPSFYSGPLGPTYPAAQLG-------PRGAAGYSWSPQRSMPPRPGYPGT 275
            +PP P   VS P         T P  Q+        P G  G   +  +    +P  P  
Sbjct: 1232 IPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCR 1291

Query: 276  PM 277
            PM
Sbjct: 1292 PM 1293


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 71/205 (34%), Positives = 83/205 (40%), Gaps = 37/205 (18%)

Query: 171 PPPRPPPPVRPVPQGTPPVVE----EQPQPP---LAMPPYPLPYSPSPSLPVGPTAHGAL 223
           PPP+ PPP +P P   PP  +    +QP PP    + P       P+P +   P A  + 
Sbjct: 72  PPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSA 131

Query: 224 PPAPFPVVSQPSFYSGPLGPT---YPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGAS 280
           PPA  P    P   SGP GPT    PA    P GA           PP  G P TP  A 
Sbjct: 132 PPATPPTSGAPP-GSGP-GPTPTPPPAVTSAPPGA-------PPPTPPSSGVPTTPPQAG 182

Query: 281 GPGYPLRGGRAPSPGYPQQSPYPA--TGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGP 338
           GP  P      P PG P+Q P P    GGK   P  P+    PG   P    +PP+  G 
Sbjct: 183 GPPPPPAAVPGPGPG-PKQGPGPGGPKGGK--MPGGPKPGGGPGLSTPGGHPKPPHRGGG 239

Query: 339 A--------PPY-----GFPPPPGP 350
                    PPY       PPP GP
Sbjct: 240 EPRGGRQHHPPYHQQHHQGPPPGGP 264



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 55/176 (31%), Positives = 61/176 (34%), Gaps = 35/176 (19%)

Query: 175 PPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQP 234
           P PP+ P     PP  ++Q QPP   PP   P  P P  P         PP P P   Q 
Sbjct: 56  PKPPIPP-----PPPHQQQQQPPPQQPP---PQQPPPHQP---------PPHPQPHQQQQ 98

Query: 235 SFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSP 294
                P   + P    GP  A G   +P  S    P  P T       G P   G  P+P
Sbjct: 99  P-PPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT------SGAPPGSGPGPTP 151

Query: 295 GYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGP 350
             P        G  PP P           P   VP  PP   GP PP    P PGP
Sbjct: 152 TPPPAVTSAPPGAPPPTP-----------PSSGVPTTPPQAGGPPPPPAAVPGPGP 196



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 51/158 (32%), Positives = 55/158 (34%), Gaps = 25/158 (15%)

Query: 168 GDAPPPRPP-PPVRPVPQGTPPVVEEQPQP------PLAMPPYPLPYSPSPSLPVGPTAH 220
           G APP     PP  P   G PP     P P        A P  P P  PS  +P  P   
Sbjct: 122 GSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQA 181

Query: 221 GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMP--PRP-GYPGTPM 277
           G  PP P  V        GP GP       GP+G           MP  P+P G PG   
Sbjct: 182 GGPPPPPAAVPG-----PGP-GPKQGPGPGGPKGG---------KMPGGPKPGGGPGLST 226

Query: 278 GASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQP 315
               P  P RGG  P  G     PY     + P P  P
Sbjct: 227 PGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 37/104 (35%), Positives = 39/104 (37%), Gaps = 17/104 (16%)

Query: 264 RSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYP--QQSPYPATGGKPPYPIQPQLPSFP 321
           RS PP  G      G  GPG    G + P P  P  QQ   P     PP    P  P  P
Sbjct: 32  RSPPPGMGL-NQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP--P 88

Query: 322 GQPQPSVPLQPPYP------------PGPAPPYGFPPPPGPAWP 353
             PQP    QPP P            PGPAP  G  PP   + P
Sbjct: 89  PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP 132



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/108 (32%), Positives = 40/108 (37%), Gaps = 13/108 (12%)

Query: 251 GPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPP 310
           GP G       P+  +PP P  P        P  P    + P P  P   P P    +PP
Sbjct: 45  GPMGPGPGQSGPKPPIPPPP--PHQQQQQPPPQQP--PPQQPPPHQPPPHPQPHQQQQPP 100

Query: 311 YPIQ----PQLPSFPGQPQPSVPLQPPY----PPGPAPPYGFPPPPGP 350
            P Q    P +   PG P P V   PP     PP   P  G PP  GP
Sbjct: 101 PPPQDSSKPVVAQGPG-PAPGVGSAPPASSSAPPATPPTSGAPPGSGP 147


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 69/237 (29%), Positives = 86/237 (36%), Gaps = 48/237 (20%)

Query: 156 VVRKPRASQELAGDAPPPRPP---------PPVRPVPQGTPPVVEEQPQPPLAMPPYPLP 206
           VV  P+   + A + PPP+ P         PP  P P   PP+     +   A PP P+ 
Sbjct: 337 VVVSPKEENK-AAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGE---AEPPGPVD 392

Query: 207 YSPSPSLPVGPTAHGALPPAPFPVVSQP----------------SFYSGP---------- 240
            +  P + + P AH A    P P+  +P                S+ SG           
Sbjct: 393 ATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMK 452

Query: 241 -LGPTYPAAQ--LGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYP 297
             GP+Y A     GP     Y        PP P  P  P     P  P      P+PGYP
Sbjct: 453 TEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIP-----PPTPGYP 507

Query: 298 QQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQP-PYPPGPAPPYGFPPPPGPAWP 353
              P       PP P  P   + P  P P + L P  YPP   PP G PP P P  P
Sbjct: 508 PPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPP 564



 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 75/222 (33%), Positives = 90/222 (40%), Gaps = 53/222 (23%)

Query: 158 RKPRASQELAGDAPPPRP-----------PPPVRPVPQGTPPVVEEQPQPPLAMPP--YP 204
           RKP  +  L G+A PP P           PPP  P P   PP +  +P PP   PP  Y 
Sbjct: 374 RKPPLAAAL-GEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPP---PPSSYM 429

Query: 205 LPYSPSPSLPVGP-------------TAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLG 251
              S + S   G               ++GALPPA  P    P ++     P  P   + 
Sbjct: 430 TGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP-YHPHVYPPNPPPPPVP 488

Query: 252 PRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSP-YPATGGKPP 310
           P  A   S+ P    PP PGYP  P     P Y        +P +P   P  P T   PP
Sbjct: 489 PPPA---SFPPPAIPPPTPGYPPPP-----PTY--------NPNFPPPPPRLPPTHAVPP 532

Query: 311 YPIQPQLPSFPGQ-PQPSVPL--QPPYPPGPAPPYGFPPPPG 349
           +P  P L   P   P P+VP   QPP PP P PP G PP  G
Sbjct: 533 HP-PPGLGLPPASYPPPAVPPGGQPPVPP-PIPPPGMPPVGG 572



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 94/365 (25%), Positives = 126/365 (34%), Gaps = 91/365 (24%)

Query: 71  YQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLE 130
           YQ L K  ++ +  K K++K            L     ++ E E  A+A  +L G +  +
Sbjct: 161 YQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRL-CK 219

Query: 131 TFLENFSSMRMLSH-----LRRVRVEKLQEVVRK-----PRASQELAGDAP-----PP-- 173
             ++ ++S  M        ++ V V+ L+++  +      +  Q++    P     PP  
Sbjct: 220 FEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSL 279

Query: 174 RPPPPVRPVPQGTPPVVEEQPQP-------------PLAMP--PYPLPYS---------- 208
           +P P V  V Q  P    E  QP             P   P  P P P S          
Sbjct: 280 QPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVV 339

Query: 209 -----------PSPSLPVGPTAHGALPPAPFPVVSQPSFYSG-----PLGPT----YPAA 248
                      P P +P   T H  LPPA  P   +P   +      P GP      P  
Sbjct: 340 SPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKV 399

Query: 249 QLGPRGAAGYSWS----PQRSMPPRP-----GYPGTPMGASGPGY-----------PLRG 288
           Q+ P             P R  PP P     G   T    SG GY           P  G
Sbjct: 400 QIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYG 459

Query: 289 GRAPSPGYPQQSPYPA---TGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPY--G 343
              P+ G P   PY         PP P+ P   SFP  P    P  P YPP P P Y   
Sbjct: 460 ALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFP--PPAIPPPTPGYPP-PPPTYNPN 516

Query: 344 FPPPP 348
           FPPPP
Sbjct: 517 FPPPP 521



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 4/91 (4%)

Query: 171 PPPRPPPPVRPVPQGTPPVVEEQPQPPLA----MPPYPLPYSPSPSLPVGPTAHGALPPA 226
           PPP PPPP    P   PP     P PP       PP P    P+ ++P  P     LPPA
Sbjct: 484 PPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPA 543

Query: 227 PFPVVSQPSFYSGPLGPTYPAAQLGPRGAAG 257
            +P  + P     P+ P  P   + P G  G
Sbjct: 544 SYPPPAVPPGGQPPVPPPIPPPGMPPVGGLG 574



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 20/53 (37%), Positives = 21/53 (39%), Gaps = 4/53 (7%)

Query: 170 APPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGA 222
           A PP PPP +   P   PP       PP   PP P P  P    PVG     A
Sbjct: 529 AVPPHPPPGLGLPPASYPP----PAVPPGGQPPVPPPIPPPGMPPVGGLGRAA 577


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 67/207 (32%), Positives = 81/207 (39%), Gaps = 35/207 (16%)

Query: 165 ELAGDAPPP--RPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGA 222
           +L  DAPPP   P P V  +  G PP     P P    PP P P +  P +P       A
Sbjct: 209 QLFADAPPPPSAPNPVVSSLGSGLPP--PGMPPPGSFPPPVPPPGALPPGIPP------A 260

Query: 223 LPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPP----RPGYPGTPMG 278
           +PP P P         G  G   P+A     G  G+  S     PP     PG     + 
Sbjct: 261 MPPPPMP--------PGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLA 312

Query: 279 ASGP---GYPLRG----GRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFP---GQPQPSV 328
             GP   G+P  G    G  P P  P   P+P   G PP  + P+ P F    G P P  
Sbjct: 313 HHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHP---GPPPMGMPPRGPPFGSPMGHPGPMP 369

Query: 329 PLQPPYPPGPAPPYGFPPPPGPAWPGY 355
           P     PP   PP+G+  PP P   GY
Sbjct: 370 PHGMRGPPPLMPPHGYTGPPRPPPYGY 396



 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 77/214 (35%), Positives = 87/214 (40%), Gaps = 42/214 (19%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYS------PSPSL 213
           P  S   +G  PP  PPP   P P   PP     P  P AMPP P+P        PS   
Sbjct: 223 PVVSSLGSGLPPPGMPPPGSFPPP--VPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGT 280

Query: 214 P-VGPTAHGALPPAPFPVVSQPS--------FYSGPLGPTYPAAQLGPRGAAGYSWSPQR 264
           P  G   HG   P PFP    P          + GP G  +P A  GP G+ G       
Sbjct: 281 PGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHA--GPPGSGG------- 331

Query: 265 SMPPRPGYPGTPMGASGP-GYPLRGGRAPSP-GYPQQSPYPATGGKPPYPIQPQLPSFPG 322
             PPRP  PG P     P G P RG    SP G+P   P P  G + P P+ P    + G
Sbjct: 332 QPPPRPP-PGMPHPGPPPMGMPPRGPPFGSPMGHP--GPMPPHGMRGPPPLMPP-HGYTG 387

Query: 323 QPQPSV------PLQPPYPPGPAPPYGFPPPPGP 350
            P+P        PL PP P  P PP    PP GP
Sbjct: 388 PPRPPPYGYQRGPLPPPRPT-PRPPV---PPRGP 417



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 62/193 (32%), Positives = 72/193 (37%), Gaps = 44/193 (22%)

Query: 168 GDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLP-VGPTAHGALPPA 226
           G  PPP PPP    +P G PP +   P PP A    P    PS   P  G   HG   P 
Sbjct: 241 GSFPPPVPPPGA--LPPGIPPAMPPPPMPPGAAGHGP----PSAGTPGAGHPGHGHSHPH 294

Query: 227 PFPVVSQPS--------FYSGPLGPTYPAAQLGPRGAAG-----------YSWSPQRSMP 267
           PFP    P          + GP G  +P A  GP G+ G           +   P   MP
Sbjct: 295 PFPPGGMPHPGMSQMQLAHHGPHGLGHPHA--GPPGSGGQPPPRPPPGMPHPGPPPMGMP 352

Query: 268 PRPGYPGTPMGASGPGYPLRGGRAPSPGYP---------------QQSPYPATGGKPPYP 312
           PR    G+PMG  GP  P  G R P P  P               Q+ P P     P  P
Sbjct: 353 PRGPPFGSPMGHPGP-MPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPP 411

Query: 313 IQPQLPSFPGQPQ 325
           + P+ P     PQ
Sbjct: 412 VPPRGPLRGPLPQ 424



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 27/81 (33%), Positives = 31/81 (38%), Gaps = 13/81 (16%)

Query: 276 PMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYP 335
           P+  +   + L     P P  P         G PP  + P     PG   P VP     P
Sbjct: 200 PLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPP-----PGSFPPPVP-----P 249

Query: 336 PGPAPPYGFPP--PPGPAWPG 354
           PG  PP G PP  PP P  PG
Sbjct: 250 PGALPP-GIPPAMPPPPMPPG 269


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 75/208 (36%), Positives = 82/208 (39%), Gaps = 35/208 (16%)

Query: 168 GDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAP 227
           G  P   P  P   VP G PP        P  +P  P P    PS+P  PT     PPAP
Sbjct: 36  GSNPWNNPSAP-SSVPSGLPPSAT-----PSTVPFGPAPTGMYPSVP--PTGPPPGPPAP 87

Query: 228 FPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMP--PRP-GYPGTPMGA----- 279
           FP  S PS    P G  YPA  +   G  G   +P    P  PRP G P  P  A     
Sbjct: 88  FPP-SGPS--CPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGP 144

Query: 280 -----SGPGYPLRGGRAPSPG--YPQQSPYPAT------GGKPPYPIQPQLPSFPGQPQP 326
                SGP  P  GG+ P+P   YP   PYPA       G  PP P     P   G P P
Sbjct: 145 WGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAP 204

Query: 327 SVPLQPPYP-PG--PAPPYGFPPPPGPA 351
                  YP PG  P P   F  P GP+
Sbjct: 205 YPAPTGSYPTPGLYPTPSNPFQVPSGPS 232



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 68/190 (35%), Positives = 76/190 (40%), Gaps = 35/190 (18%)

Query: 172 PPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVV 231
           PP  PPP  P P   PP     P P     PYP P  P P    GPT     P  PFP +
Sbjct: 76  PPTGPPPGPPAP--FPPSGPSCPPPG---GPYPAPTVPGP----GPTGPYPTPNMPFPEL 126

Query: 232 SQPSFYSGPLGPTYPAAQLGPRGAAGYS-WSPQR-------SMP-PRPG-YPGTPMG-AS 280
            +P  Y  P  P   A  LGP G+     W+P         +MP P PG YP  P   A 
Sbjct: 127 PRP--YGAPTDPA-AAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAP 183

Query: 281 GPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAP 340
           G   P+  G  P   +   +PYPA  G  P P           P PS P Q P  P  AP
Sbjct: 184 GAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTP--------GLYPTPSNPFQVPSGPSGAP 235

Query: 341 PYGFPPPPGP 350
           P     P GP
Sbjct: 236 PM----PGGP 241



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 266 MPPRPGYPGTPMGASGPG-YPLRGGRAPSPGYPQQSPYPATGGKPPYPIQP-QLPSFPGQ 323
           +PP       P G +  G YP      P PG P  +P+P +G   P P  P   P+ PG 
Sbjct: 53  LPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPP--APFPPSGPSCPPPGGPYPAPTVPG- 109

Query: 324 PQPSVPLQPPYPPGP--APPYGFPPPPGPAWP 353
           P P+ P   P  P P    PYG P  P  A P
Sbjct: 110 PGPTGPYPTPNMPFPELPRPYGAPTDPAAAGP 141



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 28/89 (31%), Positives = 32/89 (35%), Gaps = 3/89 (3%)

Query: 269 RPGYPGTPMGASGP-GYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPS 327
           +PG P      S P   P      PS   P  +P     G  P  + P +P     P P 
Sbjct: 26  KPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPP 85

Query: 328 VPLQPPYP--PGPAPPYGFPPPPGPAWPG 354
            P  P  P  P P  PY  P  PGP   G
Sbjct: 86  APFPPSGPSCPPPGGPYPAPTVPGPGPTG 114



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 4/61 (6%)

Query: 171 PPPRPPPPVRPVPQGTPPVVEEQPQPPLAMP--PYPLP-YSPSPSLPVG-PTAHGALPPA 226
           PPP+ P    PVP GT P     P  P   P   YP P   P+PS P   P+     PP 
Sbjct: 178 PPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPM 237

Query: 227 P 227
           P
Sbjct: 238 P 238


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 61/193 (31%), Positives = 73/193 (37%), Gaps = 18/193 (9%)

Query: 173  PRPPPPVRPVPQGTP--PVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPV 230
            P PP    P P+G P  P  +  P PP A PP P     +PS    PT   A PP+P   
Sbjct: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG 999

Query: 231  VSQPSFYSGPLGPTY--------PAAQLGPRGAAGYSWSPQRSMPPRP-GYP-GTPMGAS 280
             + PS    P  P          PAA   P+GA+    +P  + PP P G P  TP+   
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS----TPPAATPPSPKGSPAATPLPKG 1055

Query: 281  GPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAP 340
             P  P      PSP     +P       PP    P     P  P P     PP    P+P
Sbjct: 1056 APTTP--AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113

Query: 341  PYGFPPPPGPAWP 353
              G   PP    P
Sbjct: 1114 KGGLATPPHKGAP 1126



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 65/203 (32%), Positives = 77/203 (37%), Gaps = 24/203 (11%)

Query: 171  PPPR----PPPPVRPVPQG---TPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGAL 223
            PPP+     P    P P+G   TPP  +  P  P A PP P     +PS    PT   A 
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201

Query: 224  PPAPFPVVSQPSFYSGPLGPTY----PAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGA 279
            PP+P   ++ PS    P  P      P   L      G   +P  + P   G P TP   
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261

Query: 280  SGPGYP------LRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFP-GQPQP--SVPL 330
              P  P      L+GG A  P     +P   T   PP P      S P G P P  + P 
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVT---PPSPKGGPATSPPKGAPTPPAATPP 1318

Query: 331  QPPYPPGPAPPYGFPPPPGPAWP 353
             P   PG  PP G P PP    P
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPP 1341



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 62/195 (31%), Positives = 74/195 (37%), Gaps = 44/195 (22%)

Query: 181  PVPQGTP--PVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYS 238
            P P+G P  P  +  P PP A PP P     +PS    PT   A PP+P           
Sbjct: 925  PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP---------KG 975

Query: 239  GPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRP-GYPGTPMGASGPGYPLRGGRAPSP-GY 296
            GP  P+       P+GA     +P  + PP P G P TP     P  P      PSP G 
Sbjct: 976  GPATPS-------PKGAP----TPPAATPPSPKGGPATPSPKGAPTPP--AVTPPSPKGS 1022

Query: 297  PQQSPYPATGGKPP-------------YPIQPQLPSFPGQPQPSV---PLQPPYPPGPAP 340
            P  +P+P     PP              P+    P+ P    PS    P  P     P P
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082

Query: 341  PYGFPPPP--GPAWP 353
            P   PP P  GPA P
Sbjct: 1083 PAATPPSPKGGPATP 1097



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 63/200 (31%), Positives = 76/200 (38%), Gaps = 24/200 (12%)

Query: 173  PRPPPPVRPVPQGTP--PVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPA---- 226
            P PP    P P+G P  P  +  P PP A PP P     +PS    PT     PP+    
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022

Query: 227  ----PFPV-VSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASG 281
                PFP   S P   + P     PAA   P+GA     +P  ++P   G P TP     
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGA---PTTPAATLPSPKGGPATPSLKGA 1079

Query: 282  PGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQ----LPSFPGQPQPSVP-LQPPYPP 336
            P  P      PSP     +P P     PP    P     L + P +  P+ P   PP P 
Sbjct: 1080 PTPP--AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137

Query: 337  G---PAPPYGFPPPPGPAWP 353
            G     PP G P  P    P
Sbjct: 1138 GGLATPPPKGAPTTPAATPP 1157



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 63/199 (31%), Positives = 79/199 (39%), Gaps = 26/199 (13%)

Query: 160  PRASQELAGDAPPPRPPPPVRPVPQGTP---PVVEEQPQPPLAMPPYPLPYSPSPSLPVG 216
            P A+    G + PP   PP    P+G+P   P+ +  P  P A  P P     +PSL   
Sbjct: 1023 PAATPFPKGASTPPAATPPS---PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 217  PTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTP 276
            PT   A PP+P    + PS    P+ P   A    P+G          + PP  G P TP
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPA--ATPPSPKGGL--------ATPPHKGAPTTP 1129

Query: 277  MGASGPGYPLRGGRAP----SPGYPQQSPYPATGG--KPPYPIQPQLPSFPGQPQPSVPL 330
              A+ P  P  G   P    +P  P  +P    GG   PP    P  P+    P P   L
Sbjct: 1130 --AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGL 1186

Query: 331  QPPYPPG-PAPPYGFPPPP 348
              P P G P  P   PP P
Sbjct: 1187 ATPSPKGAPTTPAATPPSP 1205



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 63/200 (31%), Positives = 77/200 (38%), Gaps = 33/200 (16%)

Query: 167  AGDAPPPRPPPP----VRPVPQGTPPVVEEQPQPPLAMPPYPLPY-SPSPSLPVGPTAHG 221
            A   P   PP P      P P+G P      P  P   P  P P  +P+P     P+  G
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276

Query: 222  ALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRP-GYPGTPMGAS 280
             L   P      P+  + P  P    A   P+GA     +P  + PP P G PGTP    
Sbjct: 1277 GLATPPHKGAPNPAVVTPP-SPKGGPATSPPKGAP----TPPAATPPSPKGSPGTP---- 1327

Query: 281  GPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAP 340
                P +G  AP+P  P  +P P+  G P  P     PS  G P      + P PP   P
Sbjct: 1328 ----PPKG--APTP--PAVTP-PSPKGTPTLP--ATTPSSKGGPTTPSSKEGPTPPAATP 1376

Query: 341  -----PYGFPPPP--GPAWP 353
                 P   PP P  GPA P
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIP 1396



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 63/217 (29%), Positives = 83/217 (38%), Gaps = 38/217 (17%)

Query: 162  ASQELAGDAPPPRPPPPVRPVPQGTP----------------PVVEEQPQPPLAMPPYPL 205
            AS   A   P P+  P   P+P+G P                P ++  P PP A PP P 
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091

Query: 206  PYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGP--TYPAAQLG-----PRGA--- 255
                +PS    P    A PP+P   ++ P     P  P  T P+ + G     P+GA   
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 256  -AGYSWSPQRSM--PPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYP 312
             A    SP+  +  PP  G P TP  A+ P  P  G   PSP     +P       PP P
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTP--AATPPSPKGGLATPSPKGAPTTP----AATPPSP 1205

Query: 313  IQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPG 349
             +  L +   +  P+ P   P  P P      P P G
Sbjct: 1206 -KGGLATPSPKGAPTTPAATP--PSPKGGLATPSPKG 1239



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 58/217 (26%), Positives = 77/217 (35%), Gaps = 39/217 (17%)

Query: 160  PRASQELAGDAPPPRPPP-----PVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLP 214
            P  S       PP   PP     P  P P+G P      P  P   P  P   + +PS  
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP---ATTPSSK 1357

Query: 215  VGPTAHGALPPAPFPVVSQPSFYSGPL--------GPTYPAAQLGPRGAAGYSWSPQRSM 266
             GPT   +    P P  + PS   GP         GP  P+ +  P   A    SP+++ 
Sbjct: 1358 GGPTTPSS-KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA- 1415

Query: 267  PPRPGYPGTPMGASGPGYPLRGG------------RAPSPGYPQQSP-YPATGGKPPYP- 312
                  P TP+   G   P +G             +AP+   P+  P  P++ G P  P 
Sbjct: 1416 ------PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469

Query: 313  IQPQLPSFPGQP-QPSVPLQPPYPPGPAPPYGFPPPP 348
            + P  P  P  P Q +    P   P    P G P  P
Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 56/203 (27%), Positives = 74/203 (36%), Gaps = 23/203 (11%)

Query: 158  RKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVG- 216
            + P  S    G A P     P   +P  TPP  +E P P           +P+   P+G 
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPT--LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502

Query: 217  PTAHGALPPAPFPVVSQPSFYSGPLGPTYPA------AQLGPRGAAGYSWSPQRSMPPRP 270
            PT    +P +P  V + PS    P+ PT         A L P+ A      P  ++P   
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL---IPPAMTVPSPK 1559

Query: 271  GYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPL 330
              P  P     P  P     +  P        P+T    P P +  +P  P    PS P 
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVT-----PSTYKGAPSPKELLIP--PAVTSPS-PK 1611

Query: 331  QPPYPPGPAPPYGFPPPPGPAWP 353
            + P PP   PP    P  GPA P
Sbjct: 1612 EAPTPPAVTPP---SPEKGPATP 1631



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 61/211 (28%), Positives = 72/211 (34%), Gaps = 29/211 (13%)

Query: 158  RKPRASQELAGDAPPPRPPPPVRPVP-----------QGTP--PVVEEQPQPPLAMPPYP 204
            R P        D P      PV PV            QG+   P     P PP +    P
Sbjct: 807  RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP-SPKGAP 865

Query: 205  LPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQ- 263
             P + +P  P G T    LPP   P  S  +      GP  PA +  P   +  S SP+ 
Sbjct: 866  TPSAVTPLSPKGVT----LPPKETPTPSVVNLPFPKEGPATPAPKQAP-ALSMTSSSPKK 920

Query: 264  -RSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPG 322
             R+ P   G P +P     P  P      PSP     +P P     PP    P     P 
Sbjct: 921  ARATPAPKGIPASPSPKGAPTPP--AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978

Query: 323  QPQPSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
             P P      P PP   PP    P  GPA P
Sbjct: 979  TPSPK---GAPTPPAATPP---SPKGGPATP 1003



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 64/240 (26%), Positives = 83/240 (34%), Gaps = 53/240 (22%)

Query: 154  QEVVRKPRASQELAGDAPPPRP---PPPVRPVPQGTPPVVEEQPQPPLAMPPYPL--PYS 208
            +E    P  +      AP P+    PP V      T P  +E P PP   PP P   P +
Sbjct: 1577 KEASSPPAVTPSTYKGAPSPKELLIPPAV------TSPSPKEAPTPPAVTPPSPEKGPAT 1630

Query: 209  PSP-----SLPVGPTAHGALPPAPFPVVSQ-----PSFYSG---PLGPT-------YPAA 248
            P+P     S PV P++    P +P  V  +     P    G     GPT        PA 
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690

Query: 249  QLGPRGAAGYSWSPQ-----RSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYP 303
            +  P   A     PQ      + PP    P    G+ GP   +    AP+P  P Q    
Sbjct: 1691 ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV----APAPLLPVQKDSS 1746

Query: 304  ATGGKPPYPIQPQLPSFPGQPQPSVPLQP-------PYP------PGPAPPYGFPPPPGP 350
             T         P+ P  P + + S PL         P P        P+PP   P  P P
Sbjct: 1747 KTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806



 Score = 35.8 bits (81), Expect = 0.060
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 21/102 (20%)

Query: 154  QEVVRKPRASQELAGDAPP---PRPPPPVRPVP------QGTPPVVEEQPQPPLA----- 199
            ++V+ KP ++   A  +PP   P  P PV  +P        +P +V E P  PLA     
Sbjct: 1779 EKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADED 1838

Query: 200  -----MPPYPLPYS-PSPSLPVG-PTAHGALPPAPFPVVSQP 234
                 +PP P+    P  S+ V  PT   A  P P P   QP
Sbjct: 1839 ELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 47/174 (27%), Positives = 60/174 (34%), Gaps = 28/174 (16%)

Query: 171 PPPRPPPPVRPVPQGTPPVVEEQPQP-----PLAMPPYPLPYSPSPS---LPVG--PTAH 220
           P P  PPP  P PQ  P     Q  P      +A  P  +P+  S S   LP+G  P A 
Sbjct: 41  PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAP 100

Query: 221 GALPPAPFPVVSQPSF-YSGPL------GPTYPAAQLGPRGAAGYSWSPQRSMPPR--PG 271
             LP    P +S  +   + P+      G    +A L     A +S     + PP     
Sbjct: 101 TFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTS 160

Query: 272 YPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATG-GKPPYPIQPQLPSFPGQP 324
            P   +  SG    L    APS         P T   K P  + P     P  P
Sbjct: 161 PPSVAVAESGSVITLSAPIAPSE--------PKTNLNKVPSEVVPNPKGTPSPP 206



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 53/202 (26%), Positives = 75/202 (37%), Gaps = 31/202 (15%)

Query: 160  PRASQEL-AGDAPPPRPPPPVRPVPQGTPPVV---EEQPQPPLAMPPYPLPYSPSPSLPV 215
            P+AS+ L A   P       V P P+ TP +     + PQ   +    P P  P PS   
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP-PICPDPSAKN 1724

Query: 216  GPTAH-GALPPAPFPVVSQPSFYS-----------GPLGPTYPAAQLGPRGAAGYSWSPQ 263
            G       + PAP   V + S  +           GPL P    A   P  AA +    +
Sbjct: 1725 GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST-PLTAAAF----E 1779

Query: 264  RSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGY---PQQSPYPATGGKPPYPIQPQLPSF 320
            + +P     P +   ++ P  P+    APSP     P+Q   P++ G       P  P  
Sbjct: 1780 KVLPK----PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE--SPSKPLA 1833

Query: 321  PGQPQPSVPLQPPYPPGPAPPY 342
            P      +PL PP P     P+
Sbjct: 1834 PADEDELLPLIPPEPISGGVPF 1855



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 40/155 (25%), Positives = 52/155 (33%), Gaps = 24/155 (15%)

Query: 198 LAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAG 257
           LA   +P+      +LP+ PTA    P AP P  +     +  L P  P +         
Sbjct: 683 LAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKS--------- 733

Query: 258 YSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQL 317
               P  S+PP    PGT       G       AP    P++ P   +G       +  L
Sbjct: 734 ---VPSPSLPPAGTPPGT---KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787

Query: 318 PSFPGQPQP---SVPLQPPYPP------GPAPPYG 343
                 P P   SV  Q   PP      GP  P G
Sbjct: 788 TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 51/202 (25%), Positives = 69/202 (34%), Gaps = 36/202 (17%)

Query: 171  PPPRPPPPVRPVPQGTP--PVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPF 228
            P P+  P + P P+  P  P  +E   PP A+ P     +PSP   + P A  +  P   
Sbjct: 1556 PSPKKTPAI-PTPKEAPATPSSKEASSPP-AVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613

Query: 229  PVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGP----GY 284
            P     +  S   GP  PA + G   +   + S  +  P  P      MGA+ P    G 
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPK-GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672

Query: 285  PLRGGR--------APSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPP 336
            P + G         AP+P        P   G               Q + S    PP  P
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGP--------------QTKKSSATSPPICP 1718

Query: 337  GPAPPYGFPPP-----PGPAWP 353
             P+   G   P     P P  P
Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLP 1740


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 72/237 (30%), Positives = 94/237 (39%), Gaps = 44/237 (18%)

Query: 157  VRKPRASQELAGDAPPPRPP----PPVRPVP--QGTPPVVEEQPQPPLAMPPYPLPYSPS 210
            ++ P+A  +     PP  PP    PP+ P+    G PP + + P     +PP P P   S
Sbjct: 778  LQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTA--TVPPVPPPQYFS 835

Query: 211  PSLPVGPTAHGALPPA----PFPVVSQPSFYSGPLG-----------PTYPAAQLGPRGA 255
            P++ + P+    LPPA    P   V  P     PL             T P   + P G 
Sbjct: 836  PAV-ILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGV 894

Query: 256  AGYS-WSPQRSMPPRPGYPGT-PMGAS-----GPGYPLRGGRA--------PSPGYPQQS 300
            A  S  S    +P +P YP   P  A       P + ++  RA        P P  P Q 
Sbjct: 895  AALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQP 954

Query: 301  PYPATGGKPPYPIQPQLPSFPGQ----PQPSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
              P     PP P+ P  P+ P Q    PQP +P QP  PP PA P   P P  P  P
Sbjct: 955  VLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVR-PEPLQPHLP 1010



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 77/280 (27%), Positives = 93/280 (33%), Gaps = 96/280 (34%)

Query: 168 GDAPPP--RPPP-----------------PVRPVPQGTPPVVE--------------EQP 194
           G   PP  +PPP                 P++PVP   PP +               + P
Sbjct: 722 GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP 781

Query: 195 QPPL--------AMPPYPL--PYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYS------ 238
           Q PL         MPP P+  P +P   +   P A   LP A  P V  P ++S      
Sbjct: 782 QAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILP 841

Query: 239 ---GPLGPTYPAAQL---------------------------------GPRGAAGYS-WS 261
               PL P  PA  L                                  P G A  S  S
Sbjct: 842 SLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHS 901

Query: 262 PQRSMPPRPGYPGT-PMGA-----SGPGYPLRGGRA--PSPGYPQQSPYPATGGKPPYPI 313
               +P +P YP   P  A       P + ++  RA  P P  P Q   P     PP P 
Sbjct: 902 AVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPT 961

Query: 314 QPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
            P  P  P  PQP+ P QP  PP P  P     PP PA P
Sbjct: 962 LPPQPVLP--PQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 62/196 (31%), Positives = 71/196 (36%), Gaps = 35/196 (17%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMP-PYPLPYSPSPSLPVGPT 218
           P  +   A   PPP  P P  P   G P    +QP PPLA P P P   +P P +P+ P 
Sbjct: 700 PDPAMSFAPVLPPPSTPMPTGP---GQPAPPGQQP-PPLAQPTPLPQVLAPQPVVPLQPV 755

Query: 219 AHGALPP--APFPVVSQPSFYSG---PLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYP 273
               LPP  AP   V  P+       P  P  P AQ+ P+            MPP P  P
Sbjct: 756 P-PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ------------MPPIPVVP 802

Query: 274 GTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPP 333
                   P  PL G      G P   P   T   PP P           P  + PL P 
Sbjct: 803 --------PITPLAG----IDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPA 850

Query: 334 YPPGPAPPYGFPPPPG 349
            P  P      P PPG
Sbjct: 851 SPALPLQAVKLPHPPG 866



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 64/220 (29%), Positives = 78/220 (35%), Gaps = 36/220 (16%)

Query: 166 LAGDAPPPR-----PPPPVRPV-PQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTA 219
           LA  AP P      PP    PV PQ  P +   Q   P A P  P+   P+P+ P     
Sbjct: 640 LADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQ--PTAAPGLPVGSVPAPACPPSLQQ 697

Query: 220 HGALPPAPFPVVSQPSFYSGPLGPTYPAAQ-LGPRGAAGYSWSPQRSMPPRPGYPGTPMG 278
           H   P   F  V  P     P GP  PA     P   A  +  PQ  + P+P  P  P+ 
Sbjct: 698 HFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQ-VLAPQPVVPLQPVP 756

Query: 279 ASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQ-----PP 333
              P Y     +  +P   +    P    +P   + PQ+P  P  P P  PL      PP
Sbjct: 757 PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP-PITPLAGIDGLPP 815

Query: 334 ---------YPPGPAPPYGFP-----------PPPGPAWP 353
                     PP P P Y  P           PP  PA P
Sbjct: 816 ALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALP 855



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 64/207 (30%), Positives = 78/207 (37%), Gaps = 33/207 (15%)

Query: 160  PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTA 219
            P A  ++A    PP P   V+ + + TPP     PQP L  PP P+   P P+LP  P  
Sbjct: 913  PAAFPQMAPTDVPPSPHHTVQNM-RATPPQPALPPQPTL--PPQPV-LPPQPTLPPQPV- 967

Query: 220  HGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGA 279
               LPP P     QP     P+ P  P   L P+ A      P R  P +P  P     A
Sbjct: 968  ---LPPQPTRP-PQPVLPPQPMLPPQPV--LPPQPAL-----PVRPEPLQPHLPEQAAPA 1016

Query: 280  SGPGYPLRGGRAPSP-------GYPQQSPYPATGGKPPYP---------IQPQLPSFPGQ 323
            + PG  +  G  P+P         P     PA    PP P         + PQ PS    
Sbjct: 1017 ATPGSQILLGH-PAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLAT 1075

Query: 324  PQPSVPLQPPYPPGPAPPYGFPPPPGP 350
               SV   P       PP   P P GP
Sbjct: 1076 VSASVQSVPTQTATLLPPANPPLPGGP 1102



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 61/217 (28%), Positives = 80/217 (36%), Gaps = 35/217 (16%)

Query: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPT 218
           +P+  Q++        PP P++   Q T      QP PP    P    +   P+LP   T
Sbjct: 551 QPKEQQDVGSPDKARGPPVPLQV--QVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSAT 608

Query: 219 AHGALPPAPFPVVSQPSFYSGPLGPTYPAAQ-------LGPRGAAGYSWSPQRSMPPRPG 271
           +          + S  +F SG     Y  +Q       LG    A  S +     PP   
Sbjct: 609 S----------LASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSE 658

Query: 272 YPGTP-----MGA-----SGPGYPLRGGRAPS--PGYPQQSPYPATGGKP--PYPIQPQL 317
            P  P     +GA     + PG P+    AP+  P   Q  P PA    P  P P  P +
Sbjct: 659 GPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTP-M 717

Query: 318 PSFPGQPQPSVPLQPPY-PPGPAPPYGFPPPPGPAWP 353
           P+ PGQP P     PP   P P P    P P  P  P
Sbjct: 718 PTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQP 754



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 54/187 (28%), Positives = 65/187 (34%), Gaps = 22/187 (11%)

Query: 172  PPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVV 231
            PP+P  P +PV    PP     PQP L  PP P+   P P LP  P    ALP  P P+ 
Sbjct: 957  PPQPTLPPQPV---LPPQPTRPPQPVL--PPQPM-LPPQPVLPPQP----ALPVRPEPL- 1005

Query: 232  SQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRA 291
             QP           P +Q+     A Y+      +P  P  P   +    P   L     
Sbjct: 1006 -QPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPE 1064

Query: 292  PSPGYPQ---------QSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPY 342
              P +P          QS    T    P P  P LP  PG   P   +Q    P      
Sbjct: 1065 LLPQFPSSLATVSASVQSVPTQTATLLP-PANPPLPGGPGIASPCPTVQLTVEPVQEEQA 1123

Query: 343  GFPPPPG 349
                PPG
Sbjct: 1124 SQDKPPG 1130



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 60/199 (30%), Positives = 71/199 (35%), Gaps = 33/199 (16%)

Query: 162  ASQELAGDAPPPRPP-PPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAH 220
            ASQ+L   A P  PP  P  P+   +PPV    PQ   A     +P   S     G  + 
Sbjct: 1363 ASQQLLSQAGPSNPPGAPPAPLAPSSPPVTA-LPQDGAAPATSTMPEPAS-----GTASQ 1416

Query: 221  GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGAS 280
               P  P  + S+    S PL  T+ A         G +        P P    T   AS
Sbjct: 1417 AGGPGTPQGLTSELET-SQPLAETHEAPLAVQPLVVGLA-----PCTPAPEAAST-RDAS 1469

Query: 281  GPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQP-----------QLPSFPGQPQPSVP 329
             P  PL    AP P     +P PA G   P P+ P           QLPS      P  P
Sbjct: 1470 APREPLPPP-APEPSPHSGTPQPALG--QPAPLLPAAVGAVSLATSQLPS-----PPLGP 1521

Query: 330  LQPPYPPGPAPPYGFPPPP 348
              PP PP      G  PPP
Sbjct: 1522 TVPPQPPSALESDGEGPPP 1540



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 53/201 (26%), Positives = 72/201 (35%), Gaps = 31/201 (15%)

Query: 167  AGDAPPPRPPPPVRPVP----QGTPPVVEE--QPQPPLAMPPYPLPYSPSPSLPVGPTAH 220
            A +AP   PP P+  +P    Q + P  ++    + P  +    L     PS P G    
Sbjct: 1323 APEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPA 1382

Query: 221  GALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQ------RSMPPRPGYPG 274
               P +P PV + P   + P   T P    G    AG   +PQ       +  P      
Sbjct: 1383 PLAPSSP-PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHE 1441

Query: 275  TPMGASGPGYPLRGGRAPSPGYPQQ-SPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPP 333
             P+       PL  G AP    P+  S   A+  + P P        P  P+PS     P
Sbjct: 1442 APLAVQ----PLVVGLAPCTPAPEAASTRDASAPREPLP--------PPAPEPS-----P 1484

Query: 334  YPPGPAPPYGFPPPPGPAWPG 354
            +   P P  G P P  PA  G
Sbjct: 1485 HSGTPQPALGQPAPLLPAAVG 1505



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 29/72 (40%), Positives = 33/72 (45%), Gaps = 8/72 (11%)

Query: 160  PRASQELAGDAP-PPRPPPPVRPVPQ-GTPPVVEEQPQP--PLAMPPYPLPYSPSPSLPV 215
            P A+      AP  P PPP   P P  GTP     QP P  P A+    L  S  PS P+
Sbjct: 1460 PEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPL 1519

Query: 216  GPTAHGALPPAP 227
            GPT    +PP P
Sbjct: 1520 GPT----VPPQP 1527



 Score = 32.0 bits (71), Expect = 0.87
 Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 20/119 (16%)

Query: 145 LRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRP----VPQGTPPVVEEQPQPPLAM 200
           LRR  VE  QE   +P   +  A +AP P+PP P++     + +    + E     P A 
Sbjct: 42  LRRSVVESDQE---EPPGLE--AAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAP 96

Query: 201 PPYPL---PYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAA 256
            P  L   P +P      GP   G   P P P+ +           T PA   GPR  A
Sbjct: 97  APAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVE--------TAPAPDGGPREEA 147


>gi|118498339 EMI domain containing 2 [Homo sapiens]
          Length = 439

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 65/208 (31%), Positives = 74/208 (35%), Gaps = 20/208 (9%)

Query: 149 RVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYS 208
           R+  + E +    A   L   A  P  P    P P+ TPP   E   P      +P+P  
Sbjct: 133 RLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQ 192

Query: 209 PSPSLPVGPTAHGALP-PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMP 267
             P+ P GP      P PA  P        +G  GP  P   LGP G         R +P
Sbjct: 193 RRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG--------PRGLP 244

Query: 268 PRPGYPGTPMGASGPGYPLRGGRAPSPGYPQ------QSPYPATGGKPPYPIQPQLPSFP 321
              G PG P G  GP     G   PSP  PQ      Q P     G              
Sbjct: 245 GEMGRPGPP-GPPGPA----GNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299

Query: 322 GQPQPSVPLQPPYPPGPAPPYGFPPPPG 349
           G P P  P  PP PPGP  P G P  PG
Sbjct: 300 GVPGPRGPPGPPGPPGPRGPPGPPGTPG 327



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 24/68 (35%), Positives = 27/68 (39%), Gaps = 13/68 (19%)

Query: 291 APSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYP-----PGPAPPYGFP 345
           A  P  P     PA    PP   +  LP        ++PL  P P      GPA P G  
Sbjct: 154 AERPSSPDND-LPAPESTPPTWNEDFLPD-------AIPLAHPVPRQRRPTGPAGPPGQT 205

Query: 346 PPPGPAWP 353
            PPGPA P
Sbjct: 206 GPPGPAGP 213


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 59/195 (30%), Positives = 78/195 (40%), Gaps = 23/195 (11%)

Query: 172 PPRPPPPVRPVPQG-TPPVVEEQPQP---PLAMPPYPLPYSPSPSLPVGPTAHGALPPAP 227
           P   PPP++      T P +E  P P   PL  PP PL   P    P  P++    PP  
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP----PETPSSIATPPPQA 594

Query: 228 FPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPG-TPMGASGPGYP- 285
            P ++ P     P  P  P A   P+     +  P ++ P  P  P  +P+    P  P 
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654

Query: 286 ------LRGGRAPSPGYPQQSPY--PAT-----GGKPPYPIQPQLPSFPGQPQPSVPLQP 332
                 L+   +P P  P Q+P+  PA+        PP    P L + P Q  PS P  P
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714

Query: 333 PYPPGPAPPYGFPPP 347
           P  P   PP   PPP
Sbjct: 715 PMSPSATPPPQAPPP 729



 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 63/190 (33%), Positives = 78/190 (41%), Gaps = 35/190 (18%)

Query: 170 APPPRPPPPVRPV-----PQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALP 224
           A PP   PP  P      P  TPP    Q  PPLA PP  +P SP  S P+ P+A    P
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPP---PQAPPPLAAPPLQVPPSPPASPPMSPSA--TPP 754

Query: 225 PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPR-PGYPGTPMGASGPG 283
           P   P+++ P     PL       Q+ P   A    SP    PP+ P    TP       
Sbjct: 755 PRVPPLLAAP-----PL-------QVPPSPPASLPMSPLAKPPPQAPPALATP------- 795

Query: 284 YPLRGGRAPSPGYPQQSPYPATGGKPPYPI---QPQLPSFPGQPQPSVPLQPPYPPGPAP 340
            PL+   +P   +P Q+P+  +   P  P+    PQ P     P   VP  PP  P    
Sbjct: 796 -PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854

Query: 341 PYGFPPPPGP 350
           P   PP PGP
Sbjct: 855 PRR-PPTPGP 863



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 61/197 (30%), Positives = 70/197 (35%), Gaps = 31/197 (15%)

Query: 171 PPPRPPPPVRPVP-QGTP-----PVVEEQPQPP--LAMPPYPLPYSPSPSLPVGPTAHGA 222
           PPP+ PP +   P QG P     P+    PQ P  LA+PP   P SP  S P+ P A   
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA--- 646

Query: 223 LPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGP 282
            P    P          P  P        P       +SP  S P  P    TP   + P
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPP-------PSPPVQAPFSPPASPPVSPS--ATPPSQAPP 697

Query: 283 GYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPY 342
              L       P  P  SP  +    PP    P L + P Q  PS P  PP  P   PP 
Sbjct: 698 S--LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755

Query: 343 GFPP---------PPGP 350
             PP         PP P
Sbjct: 756 RVPPLLAAPPLQVPPSP 772



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 66/213 (30%), Positives = 77/213 (36%), Gaps = 22/213 (10%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSP--SPSLPVGP 217
           P+A   LA       P PP+ P+    P        PPL  PP P P SP  SP     P
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP-PASPPLSPLATPSP 650

Query: 218 TAHGAL---------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPP 268
            A  AL          P P P V  P  +S P  P    +   P  A     +P   +PP
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAP--FSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 708

Query: 269 RP--GYPGTPMGASGPGY--PLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQP 324
            P    P +P     P    PL       P  P  SP  +    PP  + P L + P Q 
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768

Query: 325 QPSVPLQPPYPPGPAPPYGFPP----PPGPAWP 353
            PS P   P  P   PP   PP    PP  A P
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 68/261 (26%), Positives = 85/261 (32%), Gaps = 68/261 (26%)

Query: 155 EVVRKPRASQELAGDA-PPPRPPP----------PVRPV-----PQGTPPVVEEQPQPPL 198
           +V   P AS  ++  A PPP+ PP          P  P      P  TPP    +  P L
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP---PRVPPLL 761

Query: 199 AMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGY 258
           A PP  +P SP  SLP+ P A    PP   P ++ P   + P  P     Q     +A  
Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKP--PPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819

Query: 259 SWSPQRSMPP---------------------------RPGYPGTPMGASGPGYPLRGGRA 291
             SP  + PP                           RP  PG     SGP   L     
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879

Query: 292 PSPGYPQQSPYPATGG-------KPPYPIQPQLPSFPGQPQPSVPLQPP----------- 333
           P P  P +SP     G               +L  +   P+      PP           
Sbjct: 880 PPPP-PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938

Query: 334 -YPPGPAPPYGFPPPPGPAWP 353
            +  GPAPP  F   PG   P
Sbjct: 939 AWSRGPAPPLAFRGAPGAPLP 959



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 63/219 (28%), Positives = 79/219 (36%), Gaps = 39/219 (17%)

Query: 161 RASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAH 220
           R S+    +   PRP P  RP P        E P+  ++         PSP+    P+A 
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPP------TEGPRKSVSSASEHSTTEPSPAARRRPSAG 231

Query: 221 GALP------------PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPP 268
           G L             P   P  S PS    P  P +P+ Q  P+G       PQ + P 
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALR-PPQVTPPR 289

Query: 269 RPGYPGT-PMGASGPGYPLRGGRAPSPGYPQQS---PYPAT--GGKP---PYPIQPQLPS 319
           +   P   P+ +S    P   G    P  P  +   P PAT     P   P P+ P  PS
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349

Query: 320 FPGQPQ--PSVPLQPPY--------PPGPAPPYGFPPPP 348
            P   Q  PS P  PP         PP  APP     PP
Sbjct: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 51/200 (25%), Positives = 71/200 (35%), Gaps = 16/200 (8%)

Query: 155 EVVRKPRASQELAGDAP---PPRPPPPVRPVPQGT-----PPVVEEQPQPPLAMPPYPLP 206
           + +R P+ +      AP   P    P   P P GT     PP        P  +PP P  
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337

Query: 207 YSPSPSLPVGPTAHGAL-----PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWS 261
            +P P  P  P+A  +L     PPA  P  + PS  + P+        + P        S
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 262 PQRSMPPRPGYPGTPMGASGPGYP-LRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSF 320
           P    PP P    +    +  G P L+   +     P+Q+    T    P    P  P  
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP-- 455

Query: 321 PGQPQPSVPLQPPYPPGPAP 340
           P Q   S+P  PP     +P
Sbjct: 456 PLQAPLSLPASPPLQTSLSP 475



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 51/206 (24%), Positives = 65/206 (31%), Gaps = 16/206 (7%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLA---MPPYPLPYSPSPSLPVG 216
           P     L+    P   P  + P+ Q    +    PQ PL+   MPP     S +P     
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPL-QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525

Query: 217 PTAHGALPPAP-FPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGT 275
           P A    PP    P ++ P   +     T P  +  P  A     +P   +   P    +
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585

Query: 276 PMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQP--SVPLQPP 333
            +    P  P      P  G P     P     P  P    LP     P P  S PL P 
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645

Query: 334 YPPGPAPPYG---------FPPPPGP 350
             P P  P           F PPP P
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSP 671



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 59/243 (24%), Positives = 78/243 (32%), Gaps = 65/243 (26%)

Query: 170 APPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFP 229
           +PP   P P+ P     PP ++  P PP   P    P   +P +   P+    +PP   P
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ-TIPPIQVP 392

Query: 230 -VVSQPSFYSGP------------------LGPTYPAAQLGPRGAAGYSWSPQRSMPPRP 270
             ++ PS  + P                  L  T+    + PR       SP R     P
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452

Query: 271 GYPGTPMGASGPGY-PLRGGRAP-----------------------SPGYP--------- 297
             P      S P   PL+   +P                       SP  P         
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512

Query: 298 --QQSPYPATGGKPPYPI-QPQLPSFPGQPQP-----SVPLQPPY---PPGPAP-PYGFP 345
             Q S  P +   PP  +  P L + P    P     S PL  P+   PP PAP P   P
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572

Query: 346 PPP 348
           P P
Sbjct: 573 PSP 575



 Score = 35.8 bits (81), Expect = 0.060
 Identities = 41/122 (33%), Positives = 48/122 (39%), Gaps = 19/122 (15%)

Query: 197 PLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAA 256
           P  + P P P SP P  PV P A   L  A            G +G    A + G  G A
Sbjct: 22  PGLLTPRP-PGSPRPPPPVTPAALRVLGAA------------GAVGRKPLAERAGGIGGA 68

Query: 257 GYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAP-----SPGYPQQSPYPATGGKPPY 311
               S  R+ P R     +   AS P    RG RAP     SPG P  SP  A+G   P 
Sbjct: 69  TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPG 127

Query: 312 PI 313
           P+
Sbjct: 128 PL 129



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 63/248 (25%), Positives = 81/248 (32%), Gaps = 69/248 (27%)

Query: 171 PP--PRPPPPVRPV---------PQGTPPVVEE---------QPQPPLAMPPYPL----- 205
           PP  PRPPPPV P            G  P+ E              P A P         
Sbjct: 29  PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88

Query: 206 -PYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLG------------- 251
            P S  P+   G  A  A   +P P VS P   SG   P  P  Q G             
Sbjct: 89  NPASRPPASGRGERAPPAKNTSPGP-VSSPGRASGTTRPG-PLGQKGLRISAEETVARGK 146

Query: 252 ----PRGAAGYSWSPQRSMPPRPGYP-----------GTPMGASGPGYPLRGGRAPSPGY 296
               P+ +A  + + + +  P PG P           GT +G   P  P    R P+ G 
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA-PSARPRPPTEG- 204

Query: 297 PQQS-----------PYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFP 345
           P++S           P PA   +P      Q P+       + PL  P   GP+      
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 346 PPPGPAWP 353
            P  P+ P
Sbjct: 265 APAHPSQP 272


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 70/237 (29%), Positives = 90/237 (37%), Gaps = 51/237 (21%)

Query: 162 ASQELAGDAPPPRPPPPVRPVPQGTP--PVVEEQPQP--------PLAMPPY-------- 203
           AS+ L+  A P   P    P  +GTP  P    QP+P        P   PP         
Sbjct: 229 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288

Query: 204 PLPYSP----SPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLG--------------PTY 245
           PL  SP    SPS P  P+A  +L   P P  + PS  +  LG              P  
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348

Query: 246 PAAQLGPRGAAGYSWSPQRSMPPRPGYPG-TPMGASGPGYP-------LRGGRAPSPGYP 297
           P A   P+     +  P ++ P  P  P  +P+    P  P       L+   +P P  P
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408

Query: 298 QQSPY--PAT-----GGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPP 347
            Q+P+  PA+        PP    P L + P Q  PS P  PP  P   PP   PPP
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 65/231 (28%), Positives = 83/231 (35%), Gaps = 52/231 (22%)

Query: 155 EVVRKPRASQELAGDAPPP-RPPPPV--------RPVPQGTP----PVVEEQPQPPLAMP 201
           +V   P AS  ++  A PP + PPP+        +P PQ  P    P ++  P PP + P
Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500

Query: 202 PYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWS 261
               P+SPS SLP+ P A    PP   PV++ P     P  P  P  Q            
Sbjct: 501 G-QAPFSPSASLPMSPLA--TPPPQAPPVLAAPLLQVPPSPPASPTLQ------------ 545

Query: 262 PQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGG-------KPPYPIQ 314
                P RP  PG     SGP   L     P P  P +SP     G              
Sbjct: 546 ----APRRPPTPGPDTSVSGPRLTLALAPGPPPP-PSRSPSSTLSGPDLAGHSSSATSTP 600

Query: 315 PQLPSFPGQPQPSVPLQPP------------YPPGPAPPYGFPPPPGPAWP 353
            +L  +   P+      PP            +  GPAPP  F   PG   P
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 651



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 60/190 (31%), Positives = 74/190 (38%), Gaps = 34/190 (17%)

Query: 170 APPPRPP------PPVRPV--PQGTPPVVEEQPQPPLAMPPYPLPYSPSP--SLPVGPTA 219
           +PPP PP      PP  P   P  TPP    Q  P LA PP  +P  PSP  S P+ P+A
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVP--PSPPASPPMSPSA 456

Query: 220 HGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMP-PRPGYPGTPMG 278
               P AP P+ + P   + P  P  P A   P         P +++P P   +PG    
Sbjct: 457 TPP-PQAPPPLAAPPLQLAKP-PPQAPPALATP---------PLQALPSPPASFPGQAPF 505

Query: 279 ASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQP--QLPSFPGQPQPSVPLQPP--- 333
           +     P+     P P  P     P     P  P  P  Q P  P  P P   +  P   
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 565

Query: 334 --YPPGPAPP 341
               PGP PP
Sbjct: 566 LALAPGPPPP 575



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 61/216 (28%), Positives = 77/216 (35%), Gaps = 38/216 (17%)

Query: 161 RASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAH 220
           R S+    +   PRP P  RP P        E P+  ++         PSP+    P+A 
Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPP------TEGPRKSVSSASEHSTTEPSPAARRRPSAG 222

Query: 221 GAL------------PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPP 268
           G L             P   P  S PS    P  P +P +Q  P+G       PQ + P 
Sbjct: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP-SQPKPKGLQALR-PPQVTPPR 280

Query: 269 RPGYPGT-PMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQ-- 325
           +   P   P+ +S    PL      +P  P   P   T   PP     Q  +  G P   
Sbjct: 281 KDAAPALGPLSSS----PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336

Query: 326 ------PSVPLQP-PYPPGPAPP-YGFPP---PPGP 350
                 PS PL P   PP  APP    PP   PP P
Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 62/239 (25%), Positives = 80/239 (33%), Gaps = 60/239 (25%)

Query: 171 PP--PRPPPPVRPV---------PQGTPPVVEE------QPQPPLAMPPYPLPYSPSPSL 213
           PP  PRPPPPV P            G  P+ E          P  A    P   S  P+ 
Sbjct: 29  PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPAS 88

Query: 214 PVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLG-----------------PRGAA 256
             G  A  A   +P P VS P   SG   P  P  Q G                 P+ +A
Sbjct: 89  GRGERAPPAKNTSPGP-VSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPKRSA 146

Query: 257 GYSWSPQRSMPPRPGYP-----------GTPMGASGPGYPLRGGRAPSPGYPQQS----- 300
             + + + +  P PG P           GT +G   P  P    R P+ G P++S     
Sbjct: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA-PSARPRPPTEG-PRKSVSSAS 204

Query: 301 ------PYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
                 P PA   +P      Q P+       + PL  P   GP+       P  P+ P
Sbjct: 205 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP 263



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 42/156 (26%), Positives = 52/156 (33%), Gaps = 39/156 (25%)

Query: 158 RKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGP 217
           ++ +A    A   P  R P  + P P G                      SP P  PV P
Sbjct: 4   KRDKAKAGAAARTPAARAPGLLTPRPPG----------------------SPRPPPPVTP 41

Query: 218 TAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPM 277
            A   L  A            G +G    A + G  G A    S  R+ P R   P    
Sbjct: 42  AALRVLGAA------------GAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP---- 85

Query: 278 GASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPI 313
            ASG G      +  SPG P  SP  A+G   P P+
Sbjct: 86  PASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPL 120


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 61/207 (29%), Positives = 77/207 (37%), Gaps = 48/207 (23%)

Query: 178 PVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSP-------SLPVGPTAH------GALP 224
           P++  P G PP   + P PP+   P+P  +   P       S PVG   +      G +P
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMP 471

Query: 225 PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGP-- 282
           P P  ++  P        P  P+  L P       W  Q+  PP P  P + M +S P  
Sbjct: 472 PPPMGMMPPPPPPPSGQPPPPPSGPLPP-------WQQQQQQPPPPPPPSSSMASSTPLP 524

Query: 283 -------------------GYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQ 323
                                  +   A SPG PQ    P     PP  +QP LP  PG 
Sbjct: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLP--PGA 581

Query: 324 PQPSVPLQPPYPPGPAPPYGFPPPPGP 350
           P P     PP PPG A     PPPP P
Sbjct: 582 PPP----PPPPPPGSAGMMYAPPPPPP 604



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 59/193 (30%), Positives = 71/193 (36%), Gaps = 43/193 (22%)

Query: 168 GDAPPPRPPPPVRPVPQGT---PPVVEEQPQPPLAMPP-------YPLPYSPSPSLPVGP 217
           G  PPP PPP  +P P  +   PP  ++Q QPP   PP        PLP+  + +     
Sbjct: 476 GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTS 535

Query: 218 TAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPG-YPGTP 276
              G++PP       Q    +    P  P  Q  P             +P  PG  P  P
Sbjct: 536 AGTGSIPP------WQQQQAAAAASPGAPQMQGNP-----------TMVPLPPGVQPPLP 578

Query: 277 MGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPS-FPGQPQPSVPLQPPYP 335
            GA  P  P      P PG       P     PP P  P  PS F       V   PP+ 
Sbjct: 579 PGAPPPPPP------PPPGSAGMMYAP-----PPPPPPPMDPSNFVTMMGMGVAGMPPFG 627

Query: 336 PGPAPPYGFPPPP 348
             PAPP   PPPP
Sbjct: 628 MPPAPP---PPPP 637



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 59/202 (29%), Positives = 70/202 (34%), Gaps = 55/202 (27%)

Query: 170 APPPRPPPP-VRPVPQGTPPVVEEQP---QPPLAMP----------PYPLPYSPSPSLPV 215
           AP   PPPP +    Q  PP +   P   +P   M           P+  P+ P PSL  
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPH-PLPSLTG 406

Query: 216 GPTAHGAL-----PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRP 270
           G   H        PP P+     P    GP    +P    GP              PP  
Sbjct: 407 GHGGHPMQHNPNGPPPPWMQPPPPPMNQGP----HPPGHHGP--------------PPMD 448

Query: 271 GYPG-TPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVP 329
            Y G TP+G+    Y L  G+          P P  G  PP P  P      GQP P  P
Sbjct: 449 QYLGSTPVGSGV--YRLHQGKG-------MMPPPPMGMMPPPPPPPS-----GQPPP--P 492

Query: 330 LQPPYPPGPAPPYGFPPPPGPA 351
              P PP        PPPP P+
Sbjct: 493 PSGPLPPWQQQQQQPPPPPPPS 514



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 37/118 (31%), Positives = 42/118 (35%), Gaps = 29/118 (24%)

Query: 160 PRASQELAGDAPPPRPP----PPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPV 215
           P   Q+ A  A P  P     P + P+P G  P     P PP A PP P P       P 
Sbjct: 543 PWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQP-----PLPPGAPPPPPPP-------PP 590

Query: 216 GPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYP 273
           G       PP P P    PS +   +G           G AG    P   MPP P  P
Sbjct: 591 GSAGMMYAPPPPPPPPMDPSNFVTMMG----------MGVAG---MPPFGMPPAPPPP 635



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 37/119 (31%), Positives = 47/119 (39%), Gaps = 39/119 (32%)

Query: 273 PGTPMGASGPGY-PLRGGRAPSPGYPQQSPYP-----ATGGKPPY----PIQPQL----- 317
           P +    SGP   PL    AP P  P  +P P      T  +PP+    P + +      
Sbjct: 326 PASVGSTSGPATTPLAS--APRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383

Query: 318 ---PSFPG-------QPQPSV-------PLQPPYPPGPAPPYGFPPPP----GPAWPGY 355
              P  PG        P PS+       P+Q   P GP PP+  PPPP    GP  PG+
Sbjct: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ-HNPNGPPPPWMQPPPPPMNQGPHPPGH 441


>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 56/158 (35%), Positives = 68/158 (43%), Gaps = 16/158 (10%)

Query: 191  EEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQL 250
            ++Q QPP A+PP   P  P+ +   GP A   L  AP  VV  P+    P G   P+ Q+
Sbjct: 987  QQQQQPPPALPPGSQPIPPTGA--AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQI 1044

Query: 251  GPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPP 310
            G    AG +  PQ+  P     P    GA  PG P  G   PSP   QQ+P     G  P
Sbjct: 1045 G---QAGSTAGPQQQQPAGAPQP----GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097

Query: 311  YPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPP 348
                      PG   P  PL PP P  P+P    P PP
Sbjct: 1098 G------SGHPGVADPGTPL-PPDPTAPSPGTVTPVPP 1128



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 25/78 (32%), Positives = 29/78 (37%), Gaps = 9/78 (11%)

Query: 160  PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMP------PYPLPYSPSPSL 213
            P+  Q      P   PP    P P G  P   +Q  PP  MP       +P    P   L
Sbjct: 1053 PQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ-TPPSMMPGAVPGSGHPGVADPGTPL 1111

Query: 214  PVGPTA--HGALPPAPFP 229
            P  PTA   G + P P P
Sbjct: 1112 PPDPTAPSPGTVTPVPPP 1129



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 39/137 (28%), Positives = 48/137 (35%), Gaps = 36/137 (26%)

Query: 167  AGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPA 226
            AG   PP    P   + Q       +Q QP  A  P  +P    P +P  P  HG   P+
Sbjct: 1029 AGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP----PGVP-PPGPHG---PS 1080

Query: 227  PFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPL 286
            PFP    P           P+   G    +G+         P    PGTP+    P  P 
Sbjct: 1081 PFPNQQTP-----------PSMMPGAVPGSGH---------PGVADPGTPL----PPDP- 1115

Query: 287  RGGRAPSPGYPQQSPYP 303
                APSPG     P P
Sbjct: 1116 ---TAPSPGTVTPVPPP 1129


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 55/174 (31%), Positives = 65/174 (37%), Gaps = 22/174 (12%)

Query: 156 VVRKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQ--PPLAMPPYPLPYSPS--- 210
           +   P+      G+ P   PPPP +P  QG PP    +PQ  PP   P  P P       
Sbjct: 32  IAGNPQGPSPQGGNKPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 89

Query: 211 ----PSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSM 266
               P  P GP   G  P  P      P   + P GP  P    GP    G      RS 
Sbjct: 90  PRSPPGKPQGPPPQGGKPQGP-----PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 144

Query: 267 PPRPGYPGTPMGASGPGYPLRGG------RAPSPGYPQQSPYPATGGKPPYPIQ 314
           P +P  P    G +  G P   G      +AP  G PQ  P P  GG+P  P Q
Sbjct: 145 PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 198



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 64/206 (31%), Positives = 74/206 (35%), Gaps = 42/206 (20%)

Query: 162 ASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHG 221
           ++Q L  D      P  +   PQG  P    +PQ P           P P  P GP   G
Sbjct: 15  SAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGP----------PPPPGKPQGPPPQG 64

Query: 222 ALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASG 281
                           + P GP  P    GP      S SP RS P +P  P  P G   
Sbjct: 65  G---------------NKPQGPPPPGKPQGPPPQGDKSRSP-RSPPGKPQGP-PPQGGKP 107

Query: 282 PGYPLRGGRAPS----PGYPQQSPYPATGGKPPYPIQ--PQLPSFPGQPQPSVPLQPPYP 335
            G P +GG  P     PG PQ  P  A GG      +  P  P  P Q + + P  PP P
Sbjct: 108 QGPPPQGGNKPQGPPPPGKPQGPP--AQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 165

Query: 336 PG------PAPPYGFPP-PPGPAWPG 354
            G       APP G P  PP P   G
Sbjct: 166 AGGNPQQPQAPPAGQPQGPPRPPQGG 191


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 68/225 (30%), Positives = 82/225 (36%), Gaps = 65/225 (28%)

Query: 171 PPPRPPPPVRPVPQGTPPVVEEQP-QPPLAMPPYPL------------PYSPSPSLPVGP 217
           PPP PPPP  P+P   PP+    P + PL  PP PL            P +P P  P  P
Sbjct: 175 PPPTPPPPPPPLP---PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP 231

Query: 218 TAHGALPPAP---------------FPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSP 262
                LPPA                 P +  P     P G  YP  +  P   A  +  P
Sbjct: 232 PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCG--YPGLKAEPASPAQDAQEP 289

Query: 263 QRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPG 322
               PP P Y      AS P  PL G  + S              + P P+ P+ PSF  
Sbjct: 290 PAPPPPLPPYASCSPRASLPAPPLPGVNSSS--------------ETPPPLPPKSPSFQA 335

Query: 323 QPQ----PSVPLQPPYPPGPAP-----PYGFP--------PPPGP 350
            PQ     ++P  PP PPG  P      +G P        PPP P
Sbjct: 336 PPQKAGAQALP-APPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAP 379



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 64/204 (31%), Positives = 73/204 (35%), Gaps = 33/204 (16%)

Query: 167 AGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYP--LPYSPSPSLPVGPTAHGALP 224
           A    PPRP  P  P P  TPP     P PP   PP P   P       P GP   G LP
Sbjct: 161 AARTAPPRPNVPAPPPP--TPP-----PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213

Query: 225 PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGA-AGYSWSPQRS---MPPRP---------G 271
               PV   P     P  PT P   L P    +  +  PQ +   +PP P         G
Sbjct: 214 VVAPPVPCAPPPPPPPPPPTPP--PLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCG 271

Query: 272 YPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQ 331
           YPG     + P    +   AP P  P   PY +   +   P  P LP      +   PL 
Sbjct: 272 YPGLKAEPASPAQDAQEPPAPPPPLP---PYASCSPRASLP-APPLPGVNSSSETPPPLP 327

Query: 332 PPYPPGPAPP-----YGFPPPPGP 350
           P  P   APP        P PP P
Sbjct: 328 PKSPSFQAPPQKAGAQALPAPPAP 351



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 45/134 (33%), Positives = 51/134 (38%), Gaps = 15/134 (11%)

Query: 216 GPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPR-GAAGYSWSPQRSMPPRPGYPG 274
           G T  G    AP P +   +  SGPL P  PA+   PR G    +    R+ PPRP  P 
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTI-SGPLIP--PAS---PRLGNTSEAHGAARTAPPRPNVPA 173

Query: 275 TPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPY 334
            P     P  P        P  P  SP       PP P+          P P  P  PP 
Sbjct: 174 PPPPTPPPPPP-----PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP 228

Query: 335 PPGPAPPYGFPPPP 348
           PP P PP   P PP
Sbjct: 229 PPPPTPP---PLPP 239



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 58/201 (28%), Positives = 71/201 (35%), Gaps = 36/201 (17%)

Query: 172 PPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVG------PTAHGAL-- 223
           PP PPPP+ P            P PPL  PP P P +P  S          P    AL  
Sbjct: 4   PPPPPPPLPP------------PPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLA 51

Query: 224 ---PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAA---GYSWSPQRSMPPRPGYP---- 273
                     V+Q +  S P   +         G+A   G S  P        G+P    
Sbjct: 52  DIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRP 111

Query: 274 -GTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQP 332
            G    A G      G RAPSP  P ++      G    P  P+L +   +   +    P
Sbjct: 112 AGQRDVAGGKTGQGPGSRAPSPRLPNKT----ISGPLIPPASPRLGN-TSEAHGAARTAP 166

Query: 333 PYPPGPAPPYGFPPPPGPAWP 353
           P P  PAPP   PPPP P  P
Sbjct: 167 PRPNVPAPPPPTPPPPPPPLP 187


>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform c [Homo sapiens]
          Length = 1152

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 59/174 (33%), Positives = 71/174 (40%), Gaps = 26/174 (14%)

Query: 191  EEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQL 250
            ++Q QPP A+PP   P  P+ +   GP A   L  AP  VV  P+    P G   P+ Q+
Sbjct: 987  QQQQQPPPALPPGSQPIPPTGA--AGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQI 1044

Query: 251  GPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPP 310
            G    AG +  PQ+  P     P    GA  PG P  G   PSP   QQ+P     G  P
Sbjct: 1045 G---QAGSTAGPQQQQPAGAPQP----GAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVP 1097

Query: 311  YPIQP----------------QLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPP 348
                P                 LPS    P P  PL PP P  P+P    P PP
Sbjct: 1098 GSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPL-PPDPTAPSPGTVTPVPP 1150



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 42/137 (30%), Positives = 49/137 (35%), Gaps = 31/137 (22%)

Query: 224  PPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283
            PP   P  SQP           P    GP    G + +P  S+ P P   G P G+ GP 
Sbjct: 992  PPPALPPGSQP---------IPPTGAAGPPAVHGLAVAPA-SVVPAPAGSGAPPGSLGPS 1041

Query: 284  YPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYG 343
              +  G+A S   PQQ              QP     PG   P VP   P+ P P P   
Sbjct: 1042 EQI--GQAGSTAGPQQQ-------------QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQ 1086

Query: 344  FPPP------PGPAWPG 354
             PP       PG   PG
Sbjct: 1087 TPPSMMPGAVPGSGHPG 1103



 Score = 36.2 bits (82), Expect = 0.046
 Identities = 45/140 (32%), Positives = 55/140 (39%), Gaps = 20/140 (14%)

Query: 167  AGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPA 226
            AG   PP    P   + Q       +Q QP  A  P  +P    P +P  P  HG   P+
Sbjct: 1029 AGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVP----PGVP-PPGPHG---PS 1080

Query: 227  PFP-VVSQPSFYSGPL-GPTYP-AAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPG 283
            PFP   + PS   G + G  +P  A   P   A    +   S  P P  PGTP+    P 
Sbjct: 1081 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPD-PGTPL----PP 1135

Query: 284  YPLRGGRAPSPGYPQQSPYP 303
             P     APSPG     P P
Sbjct: 1136 DP----TAPSPGTVTPVPPP 1151


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 70/209 (33%), Positives = 78/209 (37%), Gaps = 24/209 (11%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSL------ 213
           P A  E A  A P  PPP  R  P G  P   ++P PP    P  +P  P+P        
Sbjct: 75  PAAPAEGAPGAAP-EPPPAGRARPGGGGP---QRPGPPSPRRPL-VPAGPAPPAAKLRPP 129

Query: 214 PVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPA--AQLGPRGAAGYSWSPQRSMPPRPG 271
           P G     A  PA   V + P     P GP  PA  A L  R   G    P     P PG
Sbjct: 130 PEGSAGSCAPVPAAAAVAAGPE--PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPG 187

Query: 272 YPGTPMGA---SGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQP----QLPSFPGQP 324
            P  P  A   +G    L    A +P     +  PA     P P  P    Q P F G  
Sbjct: 188 KPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAA 247

Query: 325 QPSVPL--QPPYPPGPAPPYGFPPPPGPA 351
            P  P    PP  P PA P   PPPP PA
Sbjct: 248 APPAPAAPSPPAAPAPAAPAAAPPPPPPA 276



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 65/212 (30%), Positives = 75/212 (35%), Gaps = 29/212 (13%)

Query: 160 PRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTA 219
           P A +   G   P RP PP         P+V   P PP A    P   S     PV   A
Sbjct: 90  PPAGRARPGGGGPQRPGPP-----SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAA 144

Query: 220 HGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGA 279
             A  P P P        + P GP   AA+ GP    G    P    P +P  PG     
Sbjct: 145 AVAAGPEPAPAGP-----AKPAGPAALAARAGPGPGPGPGPGPGPG-PGKPAGPGAAQTL 198

Query: 280 SGPGYPLRGGRAPSPGYPQQS---------PYPATGGK----PPY-----PIQPQLPSFP 321
           +G    L    A +P     +         P PA  G     PP+     P  P  PS P
Sbjct: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPP 258

Query: 322 GQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
             P P+ P   P PP PAP     PP  PA P
Sbjct: 259 AAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290



 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 55/179 (30%), Positives = 68/179 (37%), Gaps = 4/179 (2%)

Query: 176 PPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPS 235
           P  + P+P+   P    Q  P +     P P +PSP     P A  A PP P P  +  +
Sbjct: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLA 281

Query: 236 FYSG-PLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSP 294
              G P GP   A  + P  AA    S   +  P P   G P G SG   P     AP+P
Sbjct: 282 RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA-AGGPAGVSGQPGPGAAAAAPAP 340

Query: 295 GYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
           G   +SP       PP   Q    S P     S+ + P    G  P     PPP P  P
Sbjct: 341 GVKAESPKRVVQAAPP-AAQTLAASGPASTAASMVIGPTM-QGALPSPAAVPPPAPGTP 397



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 27/201 (13%)

Query: 170 APPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFP 229
           AP P  P    P P   P  +   P  P A PP   P  P P+      + GA  PAP P
Sbjct: 260 APAPAAPAAAPPPPPPAPATLARPPGHP-AGPPTAAPAVPPPAAAQNGGSAGA-APAPAP 317

Query: 230 VVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGP------- 282
               P+  SG  GP   AA   P   A    SP+R +   P    T + ASGP       
Sbjct: 318 AAGGPAGVSGQPGPGAAAAAPAPGVKAE---SPKRVVQAAPPAAQT-LAASGPASTAASM 373

Query: 283 --GYPLRGG-------RAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPG-----QPQPSV 328
             G  ++G          P+PG P   P  A G       +    +  G      P    
Sbjct: 374 VIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433

Query: 329 PLQPPYPPGPAPPYGFPPPPG 349
           P  P  P  P     F  PPG
Sbjct: 434 PRLPQPPQNPTNIQNFQLPPG 454



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/114 (28%), Positives = 40/114 (35%), Gaps = 1/114 (0%)

Query: 240 PLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQ 299
           P  P   AA  G  G    S SP  +    P  P      + P  P  G   P  G PQ+
Sbjct: 45  PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104

Query: 300 SPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWP 353
            P P +  +P  P  P  P+   +P P        P   A      P P PA P
Sbjct: 105 -PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGP 157


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,957,185
Number of Sequences: 37866
Number of extensions: 2002120
Number of successful extensions: 53936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 964
Number of HSP's successfully gapped in prelim test: 2102
Number of HSP's that attempted gapping in prelim test: 12073
Number of HSP's gapped (non-prelim): 17678
length of query: 355
length of database: 18,247,518
effective HSP length: 103
effective length of query: 252
effective length of database: 14,347,320
effective search space: 3615524640
effective search space used: 3615524640
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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