Search of human proteins with 5729913

Search of human proteins with 5729913

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo
sapiens]
         (641 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]     1325   0.0  
gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]     790   0.0  
gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens]      632   0.0  
gi|218749883 alpha 1,2-mannosidase [Homo sapiens]                     325   1e-88
gi|222537737 ER degradation enhancer, mannosidase alpha-like 2 i...   193   5e-49
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [...   178   2e-44
gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Ho...   175   1e-43
gi|222537739 ER degradation enhancer, mannosidase alpha-like 2 i...   165   1e-40
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    39   0.019
gi|154813191 IQ motif containing E isoform 1 [Homo sapiens]            39   0.019
gi|154813193 IQ motif containing E isoform 2 [Homo sapiens]            39   0.019
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]            38   0.033
gi|148746195 trichohyalin [Homo sapiens]                               38   0.033
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo...    37   0.056
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo...    37   0.056
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa...    37   0.056
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    37   0.073
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    37   0.073
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    37   0.073
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    36   0.096
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    36   0.096
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            36   0.12 
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    36   0.12 
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]        35   0.16 
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]        35   0.16 
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.16 
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.16 
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.16 
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.16 
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.16 

>gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]
          Length = 641

 Score = 1325 bits (3429), Expect = 0.0
 Identities = 641/641 (100%), Positives = 641/641 (100%)

Query: 1   MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDS 60
           MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDS
Sbjct: 1   MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDS 60

Query: 61  SKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALE 120
           SKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALE
Sbjct: 61  SKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALE 120

Query: 121 EAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK 180
           EAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
Sbjct: 121 EAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK 180

Query: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240
           REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH
Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240

Query: 241 DEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLP 300
           DEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLP
Sbjct: 241 DEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLP 300

Query: 301 AFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVM 360
           AFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVM
Sbjct: 301 AFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVM 360

Query: 361 HIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEAR 420
           HIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEAR
Sbjct: 361 HIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEAR 420

Query: 421 KMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKA 480
           KMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKA
Sbjct: 421 KMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKA 480

Query: 481 GHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWY 540
           GHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWY
Sbjct: 481 GHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWY 540

Query: 541 LWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYL 600
           LWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYL
Sbjct: 541 LWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYL 600

Query: 601 YLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR 641
           YLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR
Sbjct: 601 YLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR 641


>gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]
          Length = 653

 Score =  790 bits (2041), Expect = 0.0
 Identities = 390/613 (63%), Positives = 478/613 (77%), Gaps = 19/613 (3%)

Query: 29  ATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDL-GLEDVLIPHVDAGKGAKNP 87
           A LRL+EKF+LLL+ SAFITLCFGA FFLPDSSK     L      L P  D   G   P
Sbjct: 34  AALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPG---P 90

Query: 88  GVFLIHGPDEHRHREEE----------ERLRNKIRADHEKALEEAKEKLRKSREEIRAEI 137
           G       +    R EE          E    +IR +HE+AL EAKE L+K  EEI+ +I
Sbjct: 91  GARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDI 150

Query: 138 QTEKNKVVQEMKIKENKP---LPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWDN 194
             EK KV Q+ ++++  P   LPPV     +G+   +P D  IREKR KIKEMMKHAW+N
Sbjct: 151 LLEKKKVAQD-QLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMKHAWNN 209

Query: 195 YRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNL 254
           Y+ Y WG NEL+PI++ GHS ++FG+ + GATIVDALDTL+IM +  EF + + W+E+NL
Sbjct: 210 YKGYAWGLNELKPISKGGHSSSLFGNIK-GATIVDALDTLFIMEMKHEFEEAKSWVEENL 268

Query: 255 DFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVN 314
           DF+VN+E+SVFEVNIRF+GGLL+AYYLSGEEIF+ KAV+L  KLLPAF+TP+GIPWA++N
Sbjct: 269 DFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPSGIPWALLN 328

Query: 315 LKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNG 374
           +KSG+GRNW WAS GSSILAEFGTLH+EF+HLS+L+G+  + +KVM+IR +L K+++P G
Sbjct: 329 MKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNKLEKPQG 388

Query: 375 LYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHL 434
           LYPNYLNP +G+WGQ+H SVGGLGDSFYEYLLKAWLMSDKTD EA+KMY DA++AIE HL
Sbjct: 389 LYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKMYFDAVQAIETHL 448

Query: 435 IKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTC 494
           I+KS  GLT+I EWK G LE KMGHL CFAGGMFALGAD +    A HYLELGAEIARTC
Sbjct: 449 IRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTC 508

Query: 495 HESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWG 554
           HESY+RT +KLGPE+F+FDG VEA+A RQ EKYYILRPEV+ETY Y+WR THDP+YR+W 
Sbjct: 509 HESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWA 568

Query: 555 WEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLPLDH 614
           WEA  A+E +CRVNGG+SG++DVY    ++DDVQQSFFLAETLKYLYL+FS DDLLPL+H
Sbjct: 569 WEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDDLLPLEH 628

Query: 615 WVFNTEAHPLPVL 627
           W+FN+EAH LP+L
Sbjct: 629 WIFNSEAHLLPIL 641


>gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens]
          Length = 630

 Score =  632 bits (1631), Expect = 0.0
 Identities = 324/619 (52%), Positives = 428/619 (69%), Gaps = 37/619 (5%)

Query: 31  LRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF 90
           LRL +KF+ LL LS  +TLCFGA F LP SS+ KR  L                + PG+ 
Sbjct: 17  LRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPR------------TQQPGLE 64

Query: 91  LIHGPDEHRHREEEERLRNKIRADHEKALEE----AKEKLRKSR-EEIRAEIQTEKNKVV 145
           ++     H    E+E   N   A      ++    A  + RK      R     E+    
Sbjct: 65  VVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAA 124

Query: 146 QEMKIKENKPLPP-VPIP------------NLVGIRGGDPED--NDIREKREKIKEMMKH 190
           +   I  ++P    VP               ++G R  + ++  + +R +REKIKEMM+ 
Sbjct: 125 RGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKEMMQF 184

Query: 191 AWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWI 250
           AW +Y+ Y  G NELRP+ + G+  N+FG    GAT++D+LDTLY+M L +EF + + W+
Sbjct: 185 AWQSYKRYAMGKNELRPLTKDGYEGNMFGGLS-GATVIDSLDTLYLMELKEEFQEAKAWV 243

Query: 251 EDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPW 310
            ++   +V+ E S+FEVNIR+IGGLL+A+YL+GEE+F+IKA++L EKLLPAFNTPTGIP 
Sbjct: 244 GESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTGIPK 303

Query: 311 AMVNLKSGVGRNWGWASAGSS-ILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKM 369
            +V+ KSG   NWGWA+AGSS ILAEFG+LH+EF+HL+ L+G+  + +KV +IRK+L+K+
Sbjct: 304 GVVSFKSG---NWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI 360

Query: 370 DRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEA 429
           ++P GLYPN+L+P +G W Q+H SVGGLGDSFYEYL+K+WLMS KTD EA+ MY +A+EA
Sbjct: 361 EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA 420

Query: 430 IEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAE 489
           IE +L+  S GGLT+I EW+ G L+ KMGHLACF+GGM ALGA+ ++ +K  HY EL A+
Sbjct: 421 IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ 480

Query: 490 IARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPR 549
           I +TCHESY R+  KLGPE+F F+   EAVA + +E YYILRPEV+E+Y YLWR TH+P 
Sbjct: 481 ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI 540

Query: 550 YRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDL 609
           YR+WGWE  LA+EKYCR   GFSG++DVYSSTP HD+ QQSFFLAETLKYLYLLFS DDL
Sbjct: 541 YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL 600

Query: 610 LPLDHWVFNTEAHPLPVLH 628
           L L+ WVFNTEAHPLPV H
Sbjct: 601 LSLEDWVFNTEAHPLPVNH 619


>gi|218749883 alpha 1,2-mannosidase [Homo sapiens]
          Length = 699

 Score =  325 bits (832), Expect = 1e-88
 Identities = 216/635 (34%), Positives = 329/635 (51%), Gaps = 71/635 (11%)

Query: 39  LLLILSAFITLCFGAFFF-LPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDE 97
           ++L L AF+  C   F+  L D  K   F L  E  + P + AG    NP V     P  
Sbjct: 85  MILFLLAFLLFCGLLFYINLADHWKALAFRLEEEQKMRPEI-AGLKPANPPVL----PAP 139

Query: 98  HRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLP 157
            +   + E L        ++ ++     L     +IR   Q  K+   +E   ++  P+ 
Sbjct: 140 QKADTDPENLPEISSQKTQRHIQRGPPHL-----QIRPPSQDLKDGTQEEATKRQEAPVD 194

Query: 158 PVPIPN----LVGIRGG--DPEDND--------------------------IREKREKIK 185
           P P  +    ++  RG   +PE                             +  +++ + 
Sbjct: 195 PRPEGDPQRTVISWRGAVIEPEQGTELPSRRAEVPTKPPLPPARTQGTPVHLNYRQKGVI 254

Query: 186 EMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLD 245
           ++  HAW  YR + WGH+EL+P++R       FG   +G T++DALDT++I+GL  EF +
Sbjct: 255 DVFLHAWKGYRKFAWGHDELKPVSRS--FSEWFG---LGLTLIDALDTMWILGLRKEFEE 309

Query: 246 GQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTP 305
            ++W+   L F  + +V++FE  IR +GGLL+AY+LSG+ +F  KA     +L+PAF TP
Sbjct: 310 ARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGNRLMPAFRTP 369

Query: 306 TGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKV----MH 361
           + IP++ VN+ +GV     W S   S +AE  ++ +EF  LS LTGD  + + V     H
Sbjct: 370 SKIPYSDVNIGTGVAHPPRWTS--DSTVAEVTSIQLEFRELSRLTGDKKFQEAVEKVTQH 427

Query: 362 IRKLLQKMDRPNGLYPNYLNPRTGRWGQYHT-SVGGLGDSFYEYLLKAWLMSDKTDHEAR 420
           I  L  K D   GL P ++N  +G +      ++G   DS+YEYLLK W+   K + +  
Sbjct: 428 IHGLSGKKD---GLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQLL 484

Query: 421 KMYDDAIEAIEKHLIKKSR-GGLTFIGEWKNGHLEKKMGHLACFAGGMFALGA-DGSRAD 478
           + Y +AIE +  HL++ S    LTF+GE  +G    KM HL CF  G  ALG   G  A 
Sbjct: 485 EDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHGLPAS 544

Query: 479 KAGHYLELGAEIARTCHESYDRTALKLGPESFKFD----GAVEAVAVRQAEKYYILRPEV 534
               ++EL  E+  TC++   +    L PE   F+         V V+ A+++ +LRPE 
Sbjct: 545 ----HMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600

Query: 535 IETYWYLWRFTHDPRYRQWGWEAALAIEKYCRV-NGGFSGVKDVYS-STPTHDDVQQSFF 592
           +E+ +YL+R T D +Y+ WGWE   +  ++ RV +GG+S + +V     P   D  +SFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660

Query: 593 LAETLKYLYLLFSGD-DLLPLDHWVFNTEAHPLPV 626
           L ETLKYL+LLFS D +LL LD +VFNTEAHPLP+
Sbjct: 661 LGETLKYLFLLFSDDPNLLSLDAYVFNTEAHPLPI 695


>gi|222537737 ER degradation enhancer, mannosidase alpha-like 2
           isoform 1 [Homo sapiens]
          Length = 578

 Score =  193 bits (490), Expect = 5e-49
 Identities = 160/496 (32%), Positives = 236/496 (47%), Gaps = 63/496 (12%)

Query: 161 IPNLVGIRGGDPEDNDIREKREKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGS 220
           +P   G  G D    D    RE++K M  HA+D+Y    +  +ELRP+   GH  + +GS
Sbjct: 16  LPQHHGAPGPDGSAPDPAHYRERVKAMFYHAYDSYLENAFPFDELRPLTCDGH--DTWGS 73

Query: 221 SQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYY 280
             +  T++DALDTL I+G   EF      ++D++DF ++   SVFE NIR +GGLL+A+ 
Sbjct: 74  FSL--TLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHL 131

Query: 281 LSGEEIFKIK------------AVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASA 328
           LS +   +++            A + A KLLPAF TPTG+P+  VNL  GV         
Sbjct: 132 LSKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP----GET 187

Query: 329 GSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWG 388
             +  A  GT  +EF  LS LTGD  +          L +     GL  N+++  TG+W 
Sbjct: 188 PVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWV 247

Query: 389 QYHTSVGGLGDSFYEYLLK-AWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGE 447
                +G   DS++EYL+K A L+ DK   +   M+ +  +AI  +   +      ++  
Sbjct: 248 AQDAGIGAGVDSYFEYLVKGAILLQDK---KLMAMFLEYNKAIRNY--TRFDDWYLWVQM 302

Query: 448 WKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGP 507
           +K          L  +  G+ +L  D   A              RT    Y  T  K   
Sbjct: 303 YKGTVSMPVFQSLEAYWPGLQSLIGDIDNA-------------MRTFLNYY--TVWKQFG 347

Query: 508 ESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRV 567
              +F    +   V + E  Y LRPE+IE+  YL+R T DP   + G +A  +IEK  +V
Sbjct: 348 GLPEFYNIPQGYTVEKREG-YPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKV 406

Query: 568 NGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFS-------------------GDD 608
             GF+ +KD+       D+  +SFFLAET+KYLYLLF                    G+ 
Sbjct: 407 ECGFATIKDLRDH--KLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGEC 464

Query: 609 LLPLDHWVFNTEAHPL 624
           +L    ++FNTEAHP+
Sbjct: 465 ILGAGGYIFNTEAHPI 480


>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
           [Homo sapiens]
          Length = 932

 Score =  178 bits (451), Expect = 2e-44
 Identities = 157/507 (30%), Positives = 236/507 (46%), Gaps = 78/507 (15%)

Query: 169 GGDPEDNDIREKR-EKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGS------- 220
           G +P   + ++K   ++ EM  HA+ NY  + +  +EL P+  +G       S       
Sbjct: 40  GAEPMSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDA 99

Query: 221 -SQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAY 279
             +   T++D+LDTL ++    EF D  R +  +++   +  VSVFE NIR +GGLL  +
Sbjct: 100 LGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGH 159

Query: 280 YLS-------------GEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGR-NWGW 325
            L+              +E+ ++ A QL  KLLPAFNT +G+P+  +NLK G+ +     
Sbjct: 160 SLAIMLKEKGEYMQWYNDELLQM-AKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEART 218

Query: 326 ASAGSSILAEFGTLHMEFIHLSYLTGDL---TYYKKVMHIRKLLQKMDRPNGLYPNYLNP 382
            +   +  A  GTL +EF  LS  TG      Y +K +    L +K  R + L    +N 
Sbjct: 219 GTETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDF--LWEKRQRSSNLVGVTINI 276

Query: 383 RTGRWGQYHTSVGGLGDSFYEYLLKAW-LMSDKTDHEARKMYDDAIE--------AIEKH 433
            TG W +  + VG   DS+YEYLLKA+ L+ D +  E    + DAI          ++ H
Sbjct: 277 HTGDWVRKDSGVGAGIDSYYEYLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVH 336

Query: 434 LIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIART 493
           + K      T+            M  L  F  G+  L  D                 A  
Sbjct: 337 IHKPMLNARTW------------MDALLAFFPGLQVLKGD--------------IRPAIE 370

Query: 494 CHESYDRTALKLG--PESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYR 551
            HE   +   K    PE+F  D  V           + LRPE  E+ ++L++ T DP Y 
Sbjct: 371 THEMLYQVIKKHNFLPEAFTTDFRVHWA-------QHPLRPEFAESTYFLYKATGDPYYL 423

Query: 552 QWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSG--DDL 609
           + G      + KY RV  GF+ +KDV   T +H+D   SFFLAE  KYLYLLF+   D +
Sbjct: 424 EVGKTLIENLNKYARVPCGFAAMKDV--RTGSHEDRMDSFFLAEMFKYLYLLFADKEDII 481

Query: 610 LPLDHWVFNTEAHPLPV-LHLANTTLS 635
             ++ ++F TEAH LP+ L   N ++S
Sbjct: 482 FDIEDYIFTTEAHLLPLWLSTTNQSIS 508


>gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Homo
           sapiens]
          Length = 657

 Score =  175 bits (444), Expect = 1e-43
 Identities = 154/503 (30%), Positives = 243/503 (48%), Gaps = 59/503 (11%)

Query: 164 LVGIRGGDPEDNDIR-----------EKREKIKEMMKHAWDNYRTYGWGHNELRPIARKG 212
           ++G RG  P++ + R           + R+  + M    +DNY  + +  +EL PI  +G
Sbjct: 103 VLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRG 162

Query: 213 HSPNIFGSSQMGA---------TIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVS 263
             P+    S +           T+VDALDTL IMG   EF    + + + + F  +S V 
Sbjct: 163 RGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQ 222

Query: 264 VFEVNIRFIGGLLAAYYL-------SGEEIFK-------IKAVQLAEKLLPAF-NTPTGI 308
           VFE  IR +G LL+A+ +        G+   K         A  LA +LLPAF NT TGI
Sbjct: 223 VFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGI 282

Query: 309 PWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTY-YKKVMHIRKLLQ 367
           P+  VNLK+GV  +    +   +  A  G+L +EF  LS L GD T+ +     ++ L  
Sbjct: 283 PYPRVNLKTGVPPD----TNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWN 338

Query: 368 KMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAW-LMSDKTDHEARKMYDDA 426
                 GL  N +N +TG W    + +G   DSFYEYLLK++ L  +K D E   M++ A
Sbjct: 339 LRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLE---MFNAA 395

Query: 427 IEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLEL 486
            ++I+ +L    R G     E +         ++  F+G +     D  +A   G  + +
Sbjct: 396 YQSIQNYL----RRGREACNEGEGD--PPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLI 449

Query: 487 G-AEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFT 545
           G  E A   H  Y     + G    +++  ++A  V     +Y LRPE++E+ + L++ T
Sbjct: 450 GDVEDAICLHAFYYAIWKRYGALPERYNWQLQAPDV----LFYPLRPELVESTYLLYQAT 505

Query: 546 HDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFS 605
            +P Y   G +   ++EKY +V  G++ +  V   +   +D  +SFFL+ET KYLYLLF 
Sbjct: 506 KNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKST--EDRMESFFLSETCKYLYLLFD 563

Query: 606 GDDLLPLD--HWVFNTEAHPLPV 626
            D+ +      ++F TE H + V
Sbjct: 564 EDNPVHKSGTRYMFTTEGHIVSV 586


>gi|222537739 ER degradation enhancer, mannosidase alpha-like 2
           isoform 2 [Homo sapiens]
          Length = 541

 Score =  165 bits (418), Expect = 1e-40
 Identities = 139/431 (32%), Positives = 204/431 (47%), Gaps = 59/431 (13%)

Query: 226 TIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEE 285
           T++DALDTL I+G   EF      ++D++DF ++   SVFE NIR +GGLL+A+ LS + 
Sbjct: 40  TLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKA 99

Query: 286 IFKIK------------AVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSIL 333
             +++            A + A KLLPAF TPTG+P+  VNL  GV           +  
Sbjct: 100 GVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP----GETPVTCT 155

Query: 334 AEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTS 393
           A  GT  +EF  LS LTGD  +          L +     GL  N+++  TG+W      
Sbjct: 156 AGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAG 215

Query: 394 VGGLGDSFYEYLLK-AWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGH 452
           +G   DS++EYL+K A L+ DK   +   M+ +  +AI  +   +      ++  +K   
Sbjct: 216 IGAGVDSYFEYLVKGAILLQDK---KLMAMFLEYNKAIRNY--TRFDDWYLWVQMYKGTV 270

Query: 453 LEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKF 512
                  L  +  G+ +L  D   A              RT    Y  T  K      +F
Sbjct: 271 SMPVFQSLEAYWPGLQSLIGDIDNA-------------MRTFLNYY--TVWKQFGGLPEF 315

Query: 513 DGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFS 572
               +   V + E  Y LRPE+IE+  YL+R T DP   + G +A  +IEK  +V  GF+
Sbjct: 316 YNIPQGYTVEKREG-YPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFA 374

Query: 573 GVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFS-------------------GDDLLPLD 613
            +KD+       D+  +SFFLAET+KYLYLLF                    G+ +L   
Sbjct: 375 TIKDLRDH--KLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAG 432

Query: 614 HWVFNTEAHPL 624
            ++FNTEAHP+
Sbjct: 433 GYIFNTEAHPI 443


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 24/105 (22%)

Query: 97  EHRHREEEERL---RNKIRADHEKALEEAKEKLRKSREEIRAEI-----QTEKNKVVQEM 148
           E + RE+EE++     KIR   EK + E +EK+R+  E ++ +      Q EK +  ++M
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEK-IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566

Query: 149 KIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWD 193
           + +E K            IR    ++  IRE++EKI+E  +  W+
Sbjct: 567 RRQEEK------------IR---EQEEKIREQKEKIREQEEKIWE 596



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 22/61 (36%), Positives = 37/61 (60%), Gaps = 3/61 (4%)

Query: 97  EHRHREEEERL--RNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKV-VQEMKIKEN 153
           E + RE EE++  + KIR   EK  EE K + ++ R+E  A++  ++ K+  QE KI+E 
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435

Query: 154 K 154
           +
Sbjct: 436 E 436



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 92  IHGPDEHRHREEEERLRNKIRADHEKALEEAK-----EKLRKSREEIRAEIQTEKNKVVQ 146
           +H  ++ R +EE+ +   KIR   ++  +EAK     EK+R+  E+IR   + EK    Q
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR---EQEKKMWRQ 442

Query: 147 EMKIKENKPL 156
           E KI E + +
Sbjct: 443 EEKIHEQEKI 452



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 92  IHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIK 151
           +H  ++ R +EE+   + +   D E+ + E +EK+ +  E+IR   + E+    QE KI+
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR---EQEEKIREQEEKIR 540

Query: 152 ENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKE 186
           E + +       +        E   +R + EKI+E
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE 575



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 14/93 (15%)

Query: 102 EEEERLRNKIRADHEKALEEAKEKLRKSREEIRAE--IQTEKNKVVQEMKIKENKPLPPV 159
           E+EE++R       E+ + E +EK+R+  E++  +  I+ ++ K  +E KI+E +     
Sbjct: 360 EKEEKMRRL-----EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 414

Query: 160 PIPNLVGIRGGDPEDNDIREKREKIKEMMKHAW 192
                        ++  IRE+ EKI+E  K  W
Sbjct: 415 EAKMW-------RQEEKIREQEEKIREQEKKMW 440



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 6/62 (9%)

Query: 97  EHRHREEEERLRN--KIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           E +  E+EE+++   K+R   EK + E +EK+R+ +E+IR   + E+    QE KI+E +
Sbjct: 550 EEKMGEQEEKMQEQEKMRRQEEK-IREQEEKIREQKEKIR---EQEEKIWEQEEKIREQE 605

Query: 155 PL 156
            +
Sbjct: 606 EM 607



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 32/109 (29%)

Query: 97  EHRHREEEERLRNK---IRADHEKALEEAK-----EKLRKSREEIRAE---IQTEKNKV- 144
           E + RE+EE++R +   ++   EK  E+ +     EK+R+  E+IR +   I+ +K K+ 
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588

Query: 145 VQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWD 193
            QE KI E                    ++  IRE+ E ++E  +  W+
Sbjct: 589 EQEEKIWE--------------------QEEKIREQEEMMQEQEEKMWE 617



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 8/65 (12%)

Query: 97  EHRHREEEERLRN---KIRADHEKALEEAKEKLRKSREEIRAE----IQTEKNKVVQEMK 149
           E + RE+EE++R    KIR   EK  E+ +EK+R+  E ++ +     + E+    QE K
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628

Query: 150 IKENK 154
           ++E +
Sbjct: 629 MQEQE 633



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 24/94 (25%)

Query: 97  EHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEI---RAEIQTEKNKV-VQEMKIKE 152
           E + RE+EE  R K +   ++ + + +EK+ +  E++     +I+ ++ K+  QE KI+E
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527

Query: 153 NKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKE 186
                               ++  IRE+ EKI+E
Sbjct: 528 --------------------QEEKIREQEEKIRE 541



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 15/93 (16%)

Query: 97  EHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPL 156
           E + RE+EE++R +     E+ + E +EK+R+ +EE+  E + +  ++ + M  KE K  
Sbjct: 327 EEKIREQEEKMRRQ-----EEMMWEKEEKMRR-QEEMMWEKEEKMRRLEEMMWEKEEK-- 378

Query: 157 PPVPIPNLVGIRGGDPEDNDIREKREKIKEMMK 189
                  +  +     E   IRE+ EK +E  K
Sbjct: 379 -------IRELEEKMHEQEKIREQEEKRQEEEK 404


>gi|154813191 IQ motif containing E isoform 1 [Homo sapiens]
          Length = 695

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 26/65 (40%), Positives = 39/65 (60%), Gaps = 5/65 (7%)

Query: 101 REEEERLRNKIRADHEKALE---EAKEKLRKSREEIRAEIQTEKNKV--VQEMKIKENKP 155
           R+ E +   + +AD EK LE   E +E+ R+  E +R EIQT  +K+  +QEMK +E + 
Sbjct: 414 RDLEVKQLLQAKADLEKELECAREGEEERREREEVLREEIQTLTSKLQELQEMKKEEKED 473

Query: 156 LPPVP 160
            P VP
Sbjct: 474 CPEVP 478


>gi|154813193 IQ motif containing E isoform 2 [Homo sapiens]
          Length = 679

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 26/65 (40%), Positives = 39/65 (60%), Gaps = 5/65 (7%)

Query: 101 REEEERLRNKIRADHEKALE---EAKEKLRKSREEIRAEIQTEKNKV--VQEMKIKENKP 155
           R+ E +   + +AD EK LE   E +E+ R+  E +R EIQT  +K+  +QEMK +E + 
Sbjct: 398 RDLEVKQLLQAKADLEKELECAREGEEERREREEVLREEIQTLTSKLQELQEMKKEEKED 457

Query: 156 LPPVP 160
            P VP
Sbjct: 458 CPEVP 462


>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 170

 Score = 37.7 bits (86), Expect = 0.033
 Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 7/125 (5%)

Query: 33  LSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLI 92
           L  K I   +LS   T    +   LP SS H+        + I   DAG     P    +
Sbjct: 41  LLSKIITPCLLSTHSTHSDPSATVLPGSSTHRLKGKIFHLISIAFCDAGPSLHLP----L 96

Query: 93  HG---PDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMK 149
           HG    +E + +E+E++ + K +   +K  ++ K+K +K +++ R   +  K K  ++ K
Sbjct: 97  HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156

Query: 150 IKENK 154
            K+ K
Sbjct: 157 KKKKK 161


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 37.7 bits (86), Expect = 0.033
 Identities = 23/91 (25%), Positives = 50/91 (54%), Gaps = 2/91 (2%)

Query: 99  RHREEEERLRNKIRADHE--KALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPL 156
           + +EEEERL+ ++R++ +  +  EE +E+L K  EE R E +  + ++ +E + + ++ L
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579

Query: 157 PPVPIPNLVGIRGGDPEDNDIREKREKIKEM 187
                     ++    E  + R KRE+++ +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERL 610



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 17/59 (28%), Positives = 35/59 (59%), Gaps = 3/59 (5%)

Query: 99  RHREEEERLRNKIRADHEKALEE---AKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           +  EEEERL  +++ +HE+   E   A+E+  ++RE I++ I   + ++  E   +++K
Sbjct: 660 KREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 19/57 (33%), Positives = 36/57 (63%), Gaps = 5/57 (8%)

Query: 101 REEEERLRNKIRADHEKALEEAKEKLRK-SREEIRAEIQTEKNKVVQEMKIKENKPL 156
           R+EEE+L+ +     ++ L+E +E+LRK  R+E+R E Q E+    Q+ +++  + L
Sbjct: 254 RKEEEKLQEE-EPQRQRELQEEEEQLRKLERQELRRERQEEEQ---QQQRLRREQQL 306



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 17/62 (27%), Positives = 37/62 (59%), Gaps = 3/62 (4%)

Query: 96  DEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVV-QEMKIKENK 154
           ++   RE+EER   ++R + E+  E  +++LR+ +EE R E Q  + + + +E +++  +
Sbjct: 336 EQQLRREQEERREQQLRREQEE--ERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393

Query: 155 PL 156
            L
Sbjct: 394 QL 395



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 17/64 (26%), Positives = 39/64 (60%), Gaps = 3/64 (4%)

Query: 96  DEHRHREEEERLRNKIRADHEKALEEAK--EKLRKSREEIRAE-IQTEKNKVVQEMKIKE 152
           ++   RE+EER    ++ + EK LE+ +  ++L++ +EE R + ++ E+ +  Q +K ++
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594

Query: 153 NKPL 156
            + L
Sbjct: 595 EERL 598



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 3/62 (4%)

Query: 99   RHREEEERLRNKIRAD---HEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKP 155
            RH  EEE+L  + + +    ++  +E K+ LR+ REE R   +T++    +E  ++E + 
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350

Query: 156  LP 157
             P
Sbjct: 1351 QP 1352



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 17/63 (26%), Positives = 37/63 (58%), Gaps = 6/63 (9%)

Query: 95   PDEHRHREEEERLRNK--IRADHEKALEEAKEKLRKSREE----IRAEIQTEKNKVVQEM 148
            P++ R +E E++ R +  ++ + E+ L E +EK R+   E     + E+Q E+ ++++E 
Sbjct: 978  PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037

Query: 149  KIK 151
            + K
Sbjct: 1038 REK 1040



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 6/59 (10%)

Query: 97   EHRHREEEERLRNKIRADHEKALEEAKEKLRKSRE-EIRAEIQTEKNKVVQEMKIKENK 154
            E ++REEEE     ++ + E+ L E +EK R+ RE + R E + ++ K  Q  + ++ +
Sbjct: 1167 ERQYREEEE-----LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 3/48 (6%)

Query: 96  DEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNK 143
           +E   R E+ER + +++ D E   EE +E+  K  EE R E Q  + +
Sbjct: 461 EEETERHEQERRKQQLKRDQE---EERRERWLKLEEEERREQQERREQ 505



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 22/90 (24%), Positives = 45/90 (50%), Gaps = 16/90 (17%)

Query: 97  EHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPL 156
           E R R+E+ER       + E+  +E ++ LR+ RE+ R + +  + +  ++++ KE + L
Sbjct: 919 EKRRRQEQERQYR----EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974

Query: 157 PPVPIPNLVGIRGGDPEDNDIREKREKIKE 186
                       G +PE    +E+ +K +E
Sbjct: 975 ------------GEEPEKRRRQEREKKYRE 992


>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
            sapiens]
          Length = 1591

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 16/110 (14%)

Query: 99   RHREEEERLRNKIRADHEKALEEAK---EKLRKSREEIRAEIQTEKNKVVQEMKIKENKP 155
            RH +E E    K+  DH  +LEE K   +++    +E  AEI  EK K +QE+K+K +  
Sbjct: 998  RHIQEFE----KVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVS-D 1052

Query: 156  LPPVPIPNLVGIRGGDPEDNDIR--------EKREKIKEMMKHAWDNYRT 197
            L        V +   + E ++I+        +++E +K +++   +N RT
Sbjct: 1053 LSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRT 1102


>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
            sapiens]
          Length = 1594

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 16/110 (14%)

Query: 99   RHREEEERLRNKIRADHEKALEEAK---EKLRKSREEIRAEIQTEKNKVVQEMKIKENKP 155
            RH +E E    K+  DH  +LEE K   +++    +E  AEI  EK K +QE+K+K +  
Sbjct: 998  RHIQEFE----KVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVS-D 1052

Query: 156  LPPVPIPNLVGIRGGDPEDNDIR--------EKREKIKEMMKHAWDNYRT 197
            L        V +   + E ++I+        +++E +K +++   +N RT
Sbjct: 1053 LSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRT 1102


>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
           sapiens]
          Length = 528

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 20/52 (38%), Positives = 33/52 (63%), Gaps = 3/52 (5%)

Query: 96  DEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQE 147
           +E R REEEE  R +++ + EK   E +E+LR+  EE R  I+ E+ ++ Q+
Sbjct: 194 EERRRREEEE--RERLQKEEEKRRREEEERLRREEEE-RRRIEEERLRLEQQ 242



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 15/45 (33%), Positives = 29/45 (64%), Gaps = 2/45 (4%)

Query: 96  DEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTE 140
           +E R REEEERLR +   +  + +EE + +L + +++I A + ++
Sbjct: 211 EEKRRREEEERLRRE--EEERRRIEEERLRLEQQKQQIMAALNSQ 253



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 16/59 (27%), Positives = 35/59 (59%), Gaps = 3/59 (5%)

Query: 97  EHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQE-MKIKENK 154
           E + +EEEER R +   +  + L++ +EK R+  EE     + E+ ++ +E +++++ K
Sbjct: 187 EKKRKEEEERRRRE--EEERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQK 243



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 15/59 (25%), Positives = 30/59 (50%)

Query: 98  HRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPL 156
           H+  +EE+  + K   +  +  EE +E+L+K  E+ R E +    +  +E +  E + L
Sbjct: 179 HKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERL 237


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 36.6 bits (83), Expect = 0.073
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%)

Query: 97   EHRHREEEERLRNKIRADHEKALEEAKEKL------RKSREEIRAEIQTEKNKVVQEMKI 150
            E RH+  +ER++   +  H     + KEK       RK   +I A+     +   ++ K+
Sbjct: 1595 EERHKRHKERMKQMEKLRHRSGDPKLKEKAKPADDGRKKGLDIPAKKPPGLDPPFKDKKL 1654

Query: 151  KENKPLPPVPIPNLVGIRGGDPED 174
            KE+ P+PP     L    G D +D
Sbjct: 1655 KESTPIPPAAENKLHPASGADSKD 1678


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 36.6 bits (83), Expect = 0.073
 Identities = 16/52 (30%), Positives = 32/52 (61%)

Query: 96  DEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQE 147
           ++ R   E+ER R + R   E+ L+E ++ LR  +E+++ E++ +K K  Q+
Sbjct: 714 EQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 765



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 3/54 (5%)

Query: 101 REEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           +EEEER   ++    +K  EE +E+LRK+ E  R   Q E+ +  QE + +E +
Sbjct: 653 QEEEERRHQELL---QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 8/91 (8%)

Query: 96  DEHRHREE-----EERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKI 150
           D+ R  EE     EERLR  ++A   + +E+ KE+ +K  E+  A+I  EK +  +E ++
Sbjct: 562 DKRRRLEEVKLKREERLRKVLQA--RERVEQMKEEKKKQIEQKFAQID-EKTEKAKEERL 618

Query: 151 KENKPLPPVPIPNLVGIRGGDPEDNDIREKR 181
            E K         +  +     ++ + R  R
Sbjct: 619 AEEKAKKKAAAKKMEEVEARRKQEEEARRLR 649


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 36.6 bits (83), Expect = 0.073
 Identities = 16/52 (30%), Positives = 32/52 (61%)

Query: 96  DEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQE 147
           ++ R   E+ER R + R   E+ L+E ++ LR  +E+++ E++ +K K  Q+
Sbjct: 710 EQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 3/54 (5%)

Query: 101 REEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           +EEEER   ++    +K  EE +E+LRK+ E  R   Q E+ +  QE + +E +
Sbjct: 649 QEEEERRHQELL---QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 8/91 (8%)

Query: 96  DEHRHREE-----EERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKI 150
           D+ R  EE     EERLR  ++A   + +E+ KE+ +K  E+  A+I  EK +  +E ++
Sbjct: 558 DKRRRLEEVKLKREERLRKVLQA--RERVEQMKEEKKKQIEQKFAQID-EKTEKAKEERL 614

Query: 151 KENKPLPPVPIPNLVGIRGGDPEDNDIREKR 181
            E K         +  +     ++ + R  R
Sbjct: 615 AEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 36.2 bits (82), Expect = 0.096
 Identities = 47/193 (24%), Positives = 87/193 (45%), Gaps = 28/193 (14%)

Query: 103 EEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIP 162
           E+ +L+ + +AD  +A ++ KE   K REE++        K+V+E ++K+ +    + + 
Sbjct: 323 EKAKLKRE-KADALEAKKKEKEDKEKKREELK--------KIVEEERLKKKEEKERLKVE 373

Query: 163 NLVGIRGGDPEDNDIREKREKIKEMMKHAWDNYRTYGWGHNELRPI-----ARKGHSPNI 217
                   + E   +RE++ K  E +K  W   R      ++L+ +      +    P I
Sbjct: 374 R-------EKEREKLREEKRKYVEYLKQ-WSKPRE-DMECDDLKELPEPTPVKTRLPPEI 424

Query: 218 FGSSQMGATIVDALDTLYIMGLHDEFLDG--QRWIEDNLDFSVNSEVSVFEVNIRFIGGL 275
           FG + M    ++A   L+   L DEF DG     +E+ L    +SE  + E+   F+  +
Sbjct: 425 FGDALMVLEFLNAFGELF--DLQDEFPDGVTLEVLEEAL-VGNDSEGPLCELLFFFLTAI 481

Query: 276 LAAYYLSGEEIFK 288
             A     EE+ K
Sbjct: 482 FQAIAEEEEEVAK 494



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 12/40 (30%), Positives = 27/40 (67%)

Query: 99  RHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQ 138
           +HR+E E    +IR   E+ L+E ++K+++ +E+++ + Q
Sbjct: 623 QHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQ 662



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)

Query: 101 REEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           R+ ++  R      H K  EEA  ++RK +EE + + Q +K K  QE K+KE++
Sbjct: 610 RQAKQEFRELKAEQHRKEREEAAARIRKRKEE-KLKEQEQKMKEKQE-KLKEDE 661


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 36.2 bits (82), Expect = 0.096
 Identities = 47/193 (24%), Positives = 87/193 (45%), Gaps = 28/193 (14%)

Query: 103 EEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIP 162
           E+ +L+ + +AD  +A ++ KE   K REE++        K+V+E ++K+ +    + + 
Sbjct: 323 EKAKLKRE-KADALEAKKKEKEDKEKKREELK--------KIVEEERLKKKEEKERLKVE 373

Query: 163 NLVGIRGGDPEDNDIREKREKIKEMMKHAWDNYRTYGWGHNELRPI-----ARKGHSPNI 217
                   + E   +RE++ K  E +K  W   R      ++L+ +      +    P I
Sbjct: 374 R-------EKEREKLREEKRKYVEYLKQ-WSKPRE-DMECDDLKELPEPTPVKTRLPPEI 424

Query: 218 FGSSQMGATIVDALDTLYIMGLHDEFLDG--QRWIEDNLDFSVNSEVSVFEVNIRFIGGL 275
           FG + M    ++A   L+   L DEF DG     +E+ L    +SE  + E+   F+  +
Sbjct: 425 FGDALMVLEFLNAFGELF--DLQDEFPDGVTLEVLEEAL-VGNDSEGPLCELLFFFLTAI 481

Query: 276 LAAYYLSGEEIFK 288
             A     EE+ K
Sbjct: 482 FQAIAEEEEEVAK 494



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 12/40 (30%), Positives = 27/40 (67%)

Query: 99  RHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQ 138
           +HR+E E    +IR   E+ L+E ++K+++ +E+++ + Q
Sbjct: 655 QHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQ 694



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)

Query: 101 REEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           R+ ++  R      H K  EEA  ++RK +EE + + Q +K K  QE K+KE++
Sbjct: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEE-KLKEQEQKMKEKQE-KLKEDE 693


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 5/71 (7%)

Query: 86  NPGVFLIHGPDEHRHREEEERLRNKIR--ADHEKALEEAKEKLRKSREEIRAEIQTEKNK 143
           N  + L++   E R RE+EERLR +     + E+ L E +E+LR+  E +R   + E+  
Sbjct: 187 NQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLR---EQEERL 243

Query: 144 VVQEMKIKENK 154
             QE +++E++
Sbjct: 244 CEQEERLREHE 254



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 6/67 (8%)

Query: 97  EHRHREEEERLRNKIR--ADHEKALEEAKEKLRKSREEIRAE----IQTEKNKVVQEMKI 150
           E R RE+EERL  +     + E+ L E +E+L +  E +R +     + E+    QE ++
Sbjct: 268 EERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 327

Query: 151 KENKPLP 157
            E + LP
Sbjct: 328 CEQEKLP 334



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 8/58 (13%)

Query: 97  EHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           E R RE+EERLR     + E+ L E +E+LR+  E +    + E+    QE +++E +
Sbjct: 226 EERLREQEERLR-----EQEERLCEQEERLREHEERL---CEQEERLCEQEERLREQE 275



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 97  EHRHREEEERLRNKIRAD-HEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMK 149
           E R RE+EERL  + +    E+ LEE ++ L + R +   E   E+ ++++E++
Sbjct: 317 EERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVE 370



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 6/64 (9%)

Query: 97  EHRHREEEERL--RNKIRADHEKALEEAKEKLRKSREEIRAE----IQTEKNKVVQEMKI 150
           E R RE+EERL  + +   +HE+ L E +E+L +  E +R +     + E+    QE ++
Sbjct: 233 EERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERL 292

Query: 151 KENK 154
           +E +
Sbjct: 293 REQE 296


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 23/100 (23%)

Query: 97  EHRHREEEERL--RNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKV-VQEMKIKEN 153
           E + RE EE++  + KIR   EK  EE K + ++ R+E  A++  ++ K+  QE KI+E 
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402

Query: 154 KPLPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWD 193
           + +                    ++E+ EK+ E  +  W+
Sbjct: 403 EEM--------------------MQEQEEKMGEQEEKMWE 422



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 22/107 (20%)

Query: 92  IHGPDEHRHREEEERLRNKIRADHEKALEEAK-----EKLRKSREEIRAE---IQTEKNK 143
           +H  ++ R +EE+ +   KIR   ++  +EAK     EK+R+  E+IR +   +Q ++ K
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412

Query: 144 V-VQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMK 189
           +  QE K+ E +                  ++  +R + EKI+E  K
Sbjct: 413 MGEQEEKMWEQE-------------EEMQEQEEKMRRQEEKIREQEK 446



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 25/92 (27%)

Query: 97  EHRHREEEERLR--NKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENK 154
           E + RE+EE++R   ++  + E+ + E +EK+ +  EE++   + E+    QE KI+E  
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ---EQEEKMRRQEEKIRE-- 443

Query: 155 PLPPVPIPNLVGIRGGDPEDNDIREKREKIKE 186
                             ++  IRE+ EKI+E
Sbjct: 444 ------------------QEKKIREQEEKIRE 457



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 35/118 (29%)

Query: 97  EHRHREEEERLRN---KIRADHEKALEEAKEKLRKSRE-----------------EIRAE 136
           E   +E+EE++R    KIR + EK + E +EK+R+  E                 E  A+
Sbjct: 424 EEEMQEQEEKMRRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482

Query: 137 IQTEKNKV-VQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWD 193
           +Q ++ K+  QE KI+E +            IR    ++  IRE+ E ++E  +  W+
Sbjct: 483 MQEQEEKMRRQEEKIREQEK----------KIR---EQEEKIREQEEMMQEQEEKMWE 527



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 20/102 (19%)

Query: 97  EHRHREEEERLR----------NKIRADHEKALEEAKEKLRKSREEI--RAEIQTEKNKV 144
           E + RE+EE++R           K+R   E+ + E +EK+R+  E++  + +I+ ++ K 
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366

Query: 145 VQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKE 186
            +E KI+E +                  ++  IRE+ EKI+E
Sbjct: 367 QEEEKIREQEKRQEQEAKMW-------RQEEKIREQEEKIRE 401



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 21/107 (19%)

Query: 94  GPDEHRHREEEERLRN---KIRADHEKALEEAKEKLRKSREEIRAE---IQTEKNKV--- 144
           G  E +  E+EE ++    K+R   EK  E+ K K+R+  E+IR +   +Q ++ K+   
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK-KIREQEEKIREQEEMMQEQEEKMGEQ 472

Query: 145 -----VQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKE 186
                 QE K++E +         +        ++  IRE+ EKI+E
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKI------REQEKKIREQEEKIRE 513


>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
          Length = 285

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 102 EEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPI 161
           EEEE+    +    E A E+A+ +          + + E+ K  ++  ++E+KP P   +
Sbjct: 12  EEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFM 71

Query: 162 PNLVGIRGGDPED---NDIREKR 181
           PNLV  +  D E    +DI  KR
Sbjct: 72  PNLVPPKIPDGERVDFDDIHRKR 94



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 8/74 (10%)

Query: 91  LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSRE--------EIRAEIQTEKN 142
           LI    E+R +EEEE +  K R +  +A    ++++R  RE        E RA  + E+N
Sbjct: 105 LIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEEN 164

Query: 143 KVVQEMKIKENKPL 156
           +   E + ++ K L
Sbjct: 165 RRKAEDEARKKKAL 178


>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
          Length = 288

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 102 EEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPI 161
           EEEE+    +    E A E+A+ +          + + E+ K  ++  ++E+KP P   +
Sbjct: 12  EEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFM 71

Query: 162 PNLVGIRGGDPED---NDIREKR 181
           PNLV  +  D E    +DI  KR
Sbjct: 72  PNLVPPKIPDGERVDFDDIHRKR 94



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 8/74 (10%)

Query: 91  LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSRE--------EIRAEIQTEKN 142
           LI    E+R +EEEE +  K R +  +A    ++++R  RE        E RA  + E+N
Sbjct: 105 LIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEEN 164

Query: 143 KVVQEMKIKENKPL 156
           +   E + ++ K L
Sbjct: 165 RRKAEDEARKKKAL 178


>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 86  NPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRK--SREEIRAEIQTEKNK 143
           N  + L++   E R RE+EERLR +     E+ L+E  EKLR+    + +  E+  E   
Sbjct: 321 NQHISLLNRRQEERIREQEERLRKQ-----EERLQEQHEKLRQLAKPQSVFEELNNENKS 375

Query: 144 VVQ-EMKIKE 152
            +Q E ++KE
Sbjct: 376 TLQLEQQVKE 385


>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 86  NPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRK--SREEIRAEIQTEKNK 143
           N  + L++   E R RE+EERLR +     E+ L+E  EKLR+    + +  E+  E   
Sbjct: 329 NQHISLLNRRQEERIREQEERLRKQ-----EERLQEQHEKLRQLAKPQSVFEELNNENKS 383

Query: 144 VVQ-EMKIKE 152
            +Q E ++KE
Sbjct: 384 TLQLEQQVKE 393


>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 86  NPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRK--SREEIRAEIQTEKNK 143
           N  + L++   E R RE+EERLR +     E+ L+E  EKLR+    + +  E+  E   
Sbjct: 321 NQHISLLNRRQEERIREQEERLRKQ-----EERLQEQHEKLRQLAKPQSVFEELNNENKS 375

Query: 144 VVQ-EMKIKE 152
            +Q E ++KE
Sbjct: 376 TLQLEQQVKE 385


>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 86  NPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRK--SREEIRAEIQTEKNK 143
           N  + L++   E R RE+EERLR +     E+ L+E  EKLR+    + +  E+  E   
Sbjct: 329 NQHISLLNRRQEERIREQEERLRKQ-----EERLQEQHEKLRQLAKPQSVFEELNNENKS 383

Query: 144 VVQ-EMKIKE 152
            +Q E ++KE
Sbjct: 384 TLQLEQQVKE 393


>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 595

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 86  NPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRK--SREEIRAEIQTEKNK 143
           N  + L++   E R RE+EERLR +     E+ L+E  EKLR+    + +  E+  E   
Sbjct: 321 NQHISLLNRRQEERIREQEERLRKQ-----EERLQEQHEKLRQLAKPQSVFEELNNENKS 375

Query: 144 VVQ-EMKIKE 152
            +Q E ++KE
Sbjct: 376 TLQLEQQVKE 385


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.139    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,852,633
Number of Sequences: 37866
Number of extensions: 1187015
Number of successful extensions: 6295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 194
Number of HSP's that attempted gapping in prelim test: 5095
Number of HSP's gapped (non-prelim): 1133
length of query: 641
length of database: 18,247,518
effective HSP length: 109
effective length of query: 532
effective length of database: 14,120,124
effective search space: 7511905968
effective search space used: 7511905968
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.