Guide to the Human Genome
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Search of human proteins with 57165410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57165410 acyl-CoA synthetase long-chain family member 6
isoform a [Homo sapiens]
         (722 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo...  1475   0.0  
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo...  1446   0.0  
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo...   994   0.0  
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo...   884   0.0  
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo...   884   0.0  
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo...   884   0.0  
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo...   315   1e-85
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo...   315   1e-85
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor...   306   6e-83
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo...   306   6e-83
gi|27477105 lipidosin [Homo sapiens]                                  159   9e-39
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]    141   2e-33
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]        90   8e-18
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]        90   8e-18
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]        65   2e-10
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...    60   9e-09
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...    60   9e-09
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...    60   9e-09
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...    59   2e-08
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...    58   4e-08
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...    49   2e-05
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    47   8e-05
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    47   8e-05
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...    45   2e-04
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    42   0.003
gi|13325057 solute carrier family 27 (fatty acid transporter), m...    38   0.038
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s...    36   0.14 
gi|62865631 solute carrier family 27 (fatty acid transporter), m...    34   0.54 
gi|13325055 solute carrier family 27 (fatty acid transporter), m...    34   0.54 
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           33   0.93 

>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
           a [Homo sapiens]
          Length = 722

 Score = 1475 bits (3819), Expect = 0.0
 Identities = 722/722 (100%), Positives = 722/722 (100%)

Query: 1   MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60
           MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA
Sbjct: 1   MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60

Query: 61  LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120
           LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV
Sbjct: 61  LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120

Query: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180
           FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ
Sbjct: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180

Query: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240
           NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER
Sbjct: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240

Query: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300
           KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF
Sbjct: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300

Query: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVY 360
           TSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVY
Sbjct: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVY 360

Query: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420
           CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK
Sbjct: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420

Query: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480
           RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY
Sbjct: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480

Query: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540
           EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV
Sbjct: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540

Query: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600
           FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN
Sbjct: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600

Query: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660
           IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL
Sbjct: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660

Query: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720
           EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI
Sbjct: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720

Query: 721 SM 722
           SM
Sbjct: 721 SM 722


>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
           b [Homo sapiens]
          Length = 722

 Score = 1446 bits (3744), Expect = 0.0
 Identities = 711/722 (98%), Positives = 714/722 (98%)

Query: 1   MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60
           MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA
Sbjct: 1   MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60

Query: 61  LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120
           LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV
Sbjct: 61  LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120

Query: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180
           FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ
Sbjct: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180

Query: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240
           NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER
Sbjct: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240

Query: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300
           KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF
Sbjct: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300

Query: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVY 360
           TSGTTGNPKGAMLTHGNVVADFSGFLKVTE    P   DV IS+LPLAHMFER++QSVVY
Sbjct: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVY 360

Query: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420
           CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK
Sbjct: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420

Query: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480
           RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY
Sbjct: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480

Query: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540
           EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV
Sbjct: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540

Query: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600
           FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN
Sbjct: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600

Query: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660
           IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL
Sbjct: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660

Query: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720
           EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI
Sbjct: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720

Query: 721 SM 722
           SM
Sbjct: 721 SM 722


>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
           sapiens]
          Length = 698

 Score =  994 bits (2571), Expect = 0.0
 Identities = 463/694 (66%), Positives = 568/694 (81%)

Query: 26  MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85
           MQ  E+ R  R+PEL D  Q+ R+L   TL+  GA AA+  +W+  RPK L+PPC+L MQ
Sbjct: 1   MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60

Query: 86  SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145
           S EV  SGGARRS +    + L ++YDD  T+Y+ F+RG+ +S NGPCLG RKP QPY+W
Sbjct: 61  SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120

Query: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205
           LSY++VA+ +E +GS L+Q   K   DQFIG+FAQNRPEW+I+E  C+ YSMV+VPLYDT
Sbjct: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180

Query: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265
           LG  AI YI+N A++S V VDKP+KA LLLE VE K  PGLK+I++MD +   L ERGQ+
Sbjct: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240

Query: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325
           CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F
Sbjct: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300

Query: 326 LKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385
           +K TE+   P   D  IS+LPLAHMFER+V+ V+ CHG ++GFFQGDIRLL DD+K L P
Sbjct: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360

Query: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445
           T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+
Sbjct: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420

Query: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505
           Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC  T PGDWT+GHV
Sbjct: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480

Query: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565
           GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD
Sbjct: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540

Query: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625
           IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I
Sbjct: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600

Query: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685
           VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL  FEQVK I +H 
Sbjct: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660

Query: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719
           ++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS
Sbjct: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694


>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score =  884 bits (2283), Expect = 0.0
 Identities = 422/672 (62%), Positives = 536/672 (79%), Gaps = 2/672 (0%)

Query: 47  FRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQL 106
           F  L    L+ +    A +  W   RP+ + P  +L  QS  +E  GGAR+ V      L
Sbjct: 9   FSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIE--GGARKGVSQKNNDL 66

Query: 107 LTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHN 166
            +  + DA+TMY+VF+RGL++S NGPCLG+RKP QPY+WLSY++V+DRAE+LGS LL   
Sbjct: 67  TSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKG 126

Query: 167 CKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVD 226
            K+  DQF+G+FAQNRPEWII ELACYTYSMV VPLYDTLGP AI +I+N ADI+ VI D
Sbjct: 127 YKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICD 186

Query: 227 KPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQA 286
            PQKA++L+ +VE+  TP LK+IILMDPF++ LK+RG+K G+ I S+   E+ G+E+ + 
Sbjct: 187 TPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRK 246

Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLP 346
           PVPP P+DLS++CFTSGTTG+PKGAM+TH N+V++ + FLK  E  + PT  DV ISYLP
Sbjct: 247 PVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLP 306

Query: 347 LAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQA 406
           LAHMFER+VQ+VVY  G RVGFFQGDIRLL+DDMK L PT+FP VPRLLNR+YDK+ ++A
Sbjct: 307 LAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEA 366

Query: 407 NTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPT 466
            TPLK++LL+ A   K  E++ GIIR+DS WD+L F KIQ SLGG VR+IVTGAAP S +
Sbjct: 367 KTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTS 426

Query: 467 VLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWA 526
           V+ F RAA+GCQVYE YGQTECT GCTFT PGDWTSGHVG PL CN++KL DV ++NY+ 
Sbjct: 427 VMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFT 486

Query: 527 CKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFK 586
              EGE+C++G NVFKGYLKDP++T+EALDSDGWLHTGDIG+WLP GTLKIIDRKK+IFK
Sbjct: 487 VNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFK 546

Query: 587 LAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTY 646
           LAQGEY+APEKIENIY RSQPV QI+VHG+SL++ LVG+VVPD +V+PS+A K G++G++
Sbjct: 547 LAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSF 606

Query: 647 ADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPEL 706
            +LC N+ +++AILED+ ++GKESGL +FEQVKAI +H + FS++NGLLTPTLKAKR EL
Sbjct: 607 EELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGEL 666

Query: 707 REYFKKQIEELY 718
            +YF+ QI+ LY
Sbjct: 667 SKYFRTQIDSLY 678


>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score =  884 bits (2283), Expect = 0.0
 Identities = 422/672 (62%), Positives = 536/672 (79%), Gaps = 2/672 (0%)

Query: 47  FRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQL 106
           F  L    L+ +    A +  W   RP+ + P  +L  QS  +E  GGAR+ V      L
Sbjct: 9   FSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIE--GGARKGVSQKNNDL 66

Query: 107 LTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHN 166
            +  + DA+TMY+VF+RGL++S NGPCLG+RKP QPY+WLSY++V+DRAE+LGS LL   
Sbjct: 67  TSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKG 126

Query: 167 CKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVD 226
            K+  DQF+G+FAQNRPEWII ELACYTYSMV VPLYDTLGP AI +I+N ADI+ VI D
Sbjct: 127 YKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICD 186

Query: 227 KPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQA 286
            PQKA++L+ +VE+  TP LK+IILMDPF++ LK+RG+K G+ I S+   E+ G+E+ + 
Sbjct: 187 TPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRK 246

Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLP 346
           PVPP P+DLS++CFTSGTTG+PKGAM+TH N+V++ + FLK  E  + PT  DV ISYLP
Sbjct: 247 PVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLP 306

Query: 347 LAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQA 406
           LAHMFER+VQ+VVY  G RVGFFQGDIRLL+DDMK L PT+FP VPRLLNR+YDK+ ++A
Sbjct: 307 LAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEA 366

Query: 407 NTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPT 466
            TPLK++LL+ A   K  E++ GIIR+DS WD+L F KIQ SLGG VR+IVTGAAP S +
Sbjct: 367 KTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTS 426

Query: 467 VLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWA 526
           V+ F RAA+GCQVYE YGQTECT GCTFT PGDWTSGHVG PL CN++KL DV ++NY+ 
Sbjct: 427 VMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFT 486

Query: 527 CKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFK 586
              EGE+C++G NVFKGYLKDP++T+EALDSDGWLHTGDIG+WLP GTLKIIDRKK+IFK
Sbjct: 487 VNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFK 546

Query: 587 LAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTY 646
           LAQGEY+APEKIENIY RSQPV QI+VHG+SL++ LVG+VVPD +V+PS+A K G++G++
Sbjct: 547 LAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSF 606

Query: 647 ADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPEL 706
            +LC N+ +++AILED+ ++GKESGL +FEQVKAI +H + FS++NGLLTPTLKAKR EL
Sbjct: 607 EELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGEL 666

Query: 707 REYFKKQIEELY 718
            +YF+ QI+ LY
Sbjct: 667 SKYFRTQIDSLY 678


>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
           a [Homo sapiens]
          Length = 739

 Score =  884 bits (2283), Expect = 0.0
 Identities = 422/672 (62%), Positives = 536/672 (79%), Gaps = 2/672 (0%)

Query: 47  FRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQL 106
           F  L    L+ +    A +  W   RP+ + P  +L  QS  +E  GGAR+ V      L
Sbjct: 65  FSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIE--GGARKGVSQKNNDL 122

Query: 107 LTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHN 166
            +  + DA+TMY+VF+RGL++S NGPCLG+RKP QPY+WLSY++V+DRAE+LGS LL   
Sbjct: 123 TSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKG 182

Query: 167 CKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVD 226
            K+  DQF+G+FAQNRPEWII ELACYTYSMV VPLYDTLGP AI +I+N ADI+ VI D
Sbjct: 183 YKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICD 242

Query: 227 KPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQA 286
            PQKA++L+ +VE+  TP LK+IILMDPF++ LK+RG+K G+ I S+   E+ G+E+ + 
Sbjct: 243 TPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRK 302

Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLP 346
           PVPP P+DLS++CFTSGTTG+PKGAM+TH N+V++ + FLK  E  + PT  DV ISYLP
Sbjct: 303 PVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLP 362

Query: 347 LAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQA 406
           LAHMFER+VQ+VVY  G RVGFFQGDIRLL+DDMK L PT+FP VPRLLNR+YDK+ ++A
Sbjct: 363 LAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEA 422

Query: 407 NTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPT 466
            TPLK++LL+ A   K  E++ GIIR+DS WD+L F KIQ SLGG VR+IVTGAAP S +
Sbjct: 423 KTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTS 482

Query: 467 VLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWA 526
           V+ F RAA+GCQVYE YGQTECT GCTFT PGDWTSGHVG PL CN++KL DV ++NY+ 
Sbjct: 483 VMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFT 542

Query: 527 CKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFK 586
              EGE+C++G NVFKGYLKDP++T+EALDSDGWLHTGDIG+WLP GTLKIIDRKK+IFK
Sbjct: 543 VNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFK 602

Query: 587 LAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTY 646
           LAQGEY+APEKIENIY RSQPV QI+VHG+SL++ LVG+VVPD +V+PS+A K G++G++
Sbjct: 603 LAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSF 662

Query: 647 ADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPEL 706
            +LC N+ +++AILED+ ++GKESGL +FEQVKAI +H + FS++NGLLTPTLKAKR EL
Sbjct: 663 EELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGEL 722

Query: 707 REYFKKQIEELY 718
            +YF+ QI+ LY
Sbjct: 723 SKYFRTQIDSLY 734


>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
           sapiens]
          Length = 720

 Score =  315 bits (806), Expect = 1e-85
 Identities = 198/599 (33%), Positives = 315/599 (52%), Gaps = 36/599 (6%)

Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
           Y WLSY++V  RA   G+GL     K  T+  I +F + R EW+I   AC+ Y+  +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQKPKTN--IAIFCETRAEWMIAAQACFMYNFQLVTL 189

Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKER 262
           Y TLG  AI + +N  +++ +I  K      L + V     P L+ II +D       E 
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSL--VPRLRHIITVDGKPPTWSEF 247

Query: 263 GQKCGVVIKSMQAVEDCGQE---NHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVV 319
            +  G+++ +M AVE  G +    +Q    P P D++++ +TSG+TG PKG M++H N++
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305

Query: 320 ADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSD- 378
           A  +G  +           DV+I YLPLAH+ E   + V   HG R+G+     + L+D 
Sbjct: 306 AGITGMAERIPELGEE---DVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360

Query: 379 ----------DMKALCPTIFPVVPRLLNRMYDKIFSQAN--TPLKRWLLEFAAKRKQAEV 426
                     D   L PT+   VP +++R+Y  + ++ +  +  +R L   A   K  ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420

Query: 427 RSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQT 486
             G  RN  + D   F K+++ LGG +R+++ G AP S T   F+     C V +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478

Query: 487 ECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKG---EGEICVRGPNVFKG 543
           E     T +   D+ +G VGAPL C  IKL + EE  Y+        GEI + G +V  G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538

Query: 544 YLKDPDRTKEAL--DSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIE 599
           Y K+  +TK     D +G  WL TGDIG++ P G LKIIDRKK + KL  GEYV+  K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598

Query: 600 NIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAI 659
                   V  I  + +S  ++++G VVP+ + +   A+K+G++GT+ +LC + +++  +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658

Query: 660 LEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
           L+ +      + L  FE    I +  + ++ + GL+T   K KR EL+ +++  IE +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717


>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
           sapiens]
          Length = 720

 Score =  315 bits (806), Expect = 1e-85
 Identities = 198/599 (33%), Positives = 315/599 (52%), Gaps = 36/599 (6%)

Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
           Y WLSY++V  RA   G+GL     K  T+  I +F + R EW+I   AC+ Y+  +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQKPKTN--IAIFCETRAEWMIAAQACFMYNFQLVTL 189

Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKER 262
           Y TLG  AI + +N  +++ +I  K      L + V     P L+ II +D       E 
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSL--VPRLRHIITVDGKPPTWSEF 247

Query: 263 GQKCGVVIKSMQAVEDCGQE---NHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVV 319
            +  G+++ +M AVE  G +    +Q    P P D++++ +TSG+TG PKG M++H N++
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305

Query: 320 ADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSD- 378
           A  +G  +           DV+I YLPLAH+ E   + V   HG R+G+     + L+D 
Sbjct: 306 AGITGMAERIPELGEE---DVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360

Query: 379 ----------DMKALCPTIFPVVPRLLNRMYDKIFSQAN--TPLKRWLLEFAAKRKQAEV 426
                     D   L PT+   VP +++R+Y  + ++ +  +  +R L   A   K  ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420

Query: 427 RSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQT 486
             G  RN  + D   F K+++ LGG +R+++ G AP S T   F+     C V +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478

Query: 487 ECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKG---EGEICVRGPNVFKG 543
           E     T +   D+ +G VGAPL C  IKL + EE  Y+        GEI + G +V  G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538

Query: 544 YLKDPDRTKEAL--DSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIE 599
           Y K+  +TK     D +G  WL TGDIG++ P G LKIIDRKK + KL  GEYV+  K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598

Query: 600 NIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAI 659
                   V  I  + +S  ++++G VVP+ + +   A+K+G++GT+ +LC + +++  +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658

Query: 660 LEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
           L+ +      + L  FE    I +  + ++ + GL+T   K KR EL+ +++  IE +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717


>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
           [Homo sapiens]
          Length = 670

 Score =  306 bits (783), Expect = 6e-83
 Identities = 200/604 (33%), Positives = 313/604 (51%), Gaps = 46/604 (7%)

Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
           Y+W++Y EV  R    GSGL     K      I +F + R EW+I    C+ Y+  +V L
Sbjct: 82  YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139

Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259
           Y TLG  A+ + +N ++ S +I      +V LLE   +    +   +K II +D   +A+
Sbjct: 140 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 192

Query: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316
            +     G  I SMQ+VE+ G       +PP    P D++IV +TSG+TG PKG M+ H 
Sbjct: 193 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 252

Query: 317 NVVADFSGFLKVTESQWAPTCA--DVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIR 374
           N++A  +G     + +  P     D +I YLPLAH+ E   +   + +G R+G+      
Sbjct: 253 NLIAGMTG-----QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPL 305

Query: 375 LLSD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKR 421
            LSD           D   L PT+   VP +++R+Y  + S  Q    +++ L +     
Sbjct: 306 TLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDY 365

Query: 422 KQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE 481
           K  +++ G   +  + + L F K++A LGG VRM+++G AP SP    F+     C + +
Sbjct: 366 KLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQ 423

Query: 482 GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGP 538
           GYG TE     T T   D+T+G VGAPL C  IKL D +E  Y         GEI + G 
Sbjct: 424 GYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQ 483

Query: 539 NVFKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVA 594
           N+  GY K+ ++T E  ++D +G  W  TGDIG++ P G L+IIDRKK + KL  GEYV+
Sbjct: 484 NISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVS 543

Query: 595 PEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKD 654
             K+E        +  I     S +++++  VVP+ + +   AQ++G+EGT+ D+C N  
Sbjct: 544 LGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPA 603

Query: 655 LKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQI 714
           ++  IL+++        L  FE    + +  + ++ + GL+T   K KR ELR ++ K I
Sbjct: 604 MEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDI 663

Query: 715 EELY 718
           E +Y
Sbjct: 664 ERMY 667


>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
           2 [Homo sapiens]
          Length = 711

 Score =  306 bits (783), Expect = 6e-83
 Identities = 200/604 (33%), Positives = 313/604 (51%), Gaps = 46/604 (7%)

Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
           Y+W++Y EV  R    GSGL     K      I +F + R EW+I    C+ Y+  +V L
Sbjct: 123 YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180

Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259
           Y TLG  A+ + +N ++ S +I      +V LLE   +    +   +K II +D   +A+
Sbjct: 181 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 233

Query: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316
            +     G  I SMQ+VE+ G       +PP    P D++IV +TSG+TG PKG M+ H 
Sbjct: 234 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 293

Query: 317 NVVADFSGFLKVTESQWAPTCA--DVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIR 374
           N++A  +G     + +  P     D +I YLPLAH+ E   +   + +G R+G+      
Sbjct: 294 NLIAGMTG-----QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPL 346

Query: 375 LLSD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKR 421
            LSD           D   L PT+   VP +++R+Y  + S  Q    +++ L +     
Sbjct: 347 TLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDY 406

Query: 422 KQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE 481
           K  +++ G   +  + + L F K++A LGG VRM+++G AP SP    F+     C + +
Sbjct: 407 KLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQ 464

Query: 482 GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGP 538
           GYG TE     T T   D+T+G VGAPL C  IKL D +E  Y         GEI + G 
Sbjct: 465 GYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQ 524

Query: 539 NVFKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVA 594
           N+  GY K+ ++T E  ++D +G  W  TGDIG++ P G L+IIDRKK + KL  GEYV+
Sbjct: 525 NISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVS 584

Query: 595 PEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKD 654
             K+E        +  I     S +++++  VVP+ + +   AQ++G+EGT+ D+C N  
Sbjct: 585 LGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPA 644

Query: 655 LKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQI 714
           ++  IL+++        L  FE    + +  + ++ + GL+T   K KR ELR ++ K I
Sbjct: 645 MEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDI 704

Query: 715 EELY 718
           E +Y
Sbjct: 705 ERMY 708


>gi|27477105 lipidosin [Homo sapiens]
          Length = 724

 Score =  159 bits (402), Expect = 9e-39
 Identities = 161/633 (25%), Positives = 279/633 (44%), Gaps = 47/633 (7%)

Query: 116 TMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFI 175
           T++++F   L   G+   LGF++ +  ++ +SY +    A     G L+   K      +
Sbjct: 104 TVHRMFYEALDKYGDLIALGFKR-QDKWEHISYSQYYLLARRAAKGFLKLGLKQAHS--V 160

Query: 176 GVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLL 235
            +   N PEW    +       +V  +Y T  P A +YI      + ++VD  ++   +L
Sbjct: 161 AILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKIL 220

Query: 236 EHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ-PDD 294
           +    K+ P LK +++   ++E    +      + + M+   +  +E   A +  Q P+ 
Sbjct: 221 KIW--KQLPHLKAVVI---YKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQ 275

Query: 295 LSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERM 354
             ++ +TSGTTGNPKG ML+  N+        +  + + A    +V +SYLPL+H+  ++
Sbjct: 276 CCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQI 335

Query: 355 VQSVVYCH-GGRVGFFQGDIRL--LSDDMKALCPTIFPVVPRLLNRMYDKIFSQA----- 406
                    G +V F + D     L + ++ + PT    VPR+  ++ ++I   A     
Sbjct: 336 YDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGF 395

Query: 407 -NTPLKRWLLEFAAKRKQAEVRSGIIR-NDSIWDELFFNKIQASLG--GCVRMIVTGAAP 462
               +  W +    ++      S +      + D L   K++ +LG   C +    GAAP
Sbjct: 396 IRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFY-GAAP 454

Query: 463 ASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEEL 522
                  F    L  ++Y GYG +E +     ++P ++     G  +P   +KLV+ +  
Sbjct: 455 MMAETQHFF-LGLNIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQD-- 511

Query: 523 NYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKK 582
                +G GEIC+ G  +F GYL   D+T EA+D +GWLHTGD G+    G L I  R K
Sbjct: 512 ----AEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLK 567

Query: 583 HIFKLAQGEYVAPEKIENIYIRSQP-VAQIYVHGDSLKAFLVGIVV-----PD------- 629
            +   A GE V P  IE       P ++   + GD  K   + + +     PD       
Sbjct: 568 ELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDN 627

Query: 630 -PEVMPSWAQKRGIEG-TYADLCTNKD--LKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685
             E    + Q+ G    T +++   KD  + +AI E + R+   +    +   K   +  
Sbjct: 628 LTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILER 687

Query: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
           D FS+  G L PT+K KR  + E +K  I+  Y
Sbjct: 688 D-FSISGGELGPTMKLKRLTVLEKYKGIIDSFY 719


>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
          Length = 666

 Score =  141 bits (355), Expect = 2e-33
 Identities = 156/646 (24%), Positives = 292/646 (45%), Gaps = 65/646 (10%)

Query: 111 YDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKAC 170
           ++   T+ + FR  ++  G  P L  +  K+ ++ L++ +  +        L+    K  
Sbjct: 47  HETPMTIPEFFRESVNRFGTYPALASKNGKK-WEILNFNQYYEACRKAAKSLI----KLG 101

Query: 171 TDQF--IGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKP 228
            ++F  +G+   N  EW I  +       + V +Y T      +Y+I  A ++ ++V+  
Sbjct: 102 LERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVEND 161

Query: 229 QKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQ--KCGVVIKSMQAVEDCGQENHQA 286
           Q+   +L   +    P LK II    +   +K+          ++  +++ D   E  Q 
Sbjct: 162 QQLQKILSIPQSSLEP-LKAII---QYRLPMKKNNNLYSWDDFMELGRSIPDTQLE--QV 215

Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVV---ADFSGFLKVTESQWAPTCADVHIS 343
               + +  +++ +TSGTTG PKG ML+H N+       +   K+T+        +  +S
Sbjct: 216 IESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDKH------ETVVS 269

Query: 344 YLPLAHMFERMVQSVVYCHGGRVGFF-QGDIR--LLSDDMKALCPTIFPVVPRLLNRMYD 400
           YLPL+H+  +M+   V    G + +F Q D     L   +K + PT+F  VP++  ++++
Sbjct: 270 YLPLSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHE 329

Query: 401 KIF--SQANTPLKR----WL--LEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLG-G 451
            +   S  +  LK+    W   + F    K+   +     +  +   L F+K++ SLG  
Sbjct: 330 MVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLD 389

Query: 452 CVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPC 511
                ++G AP +     F   +L   + E YG +E +   T +   ++        L C
Sbjct: 390 HCHSFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNYRL------LSC 442

Query: 512 NHIKLVDVEELNYWACK-GEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWL 570
             I L   + + +   K G GEIC+ G ++F GYL+    T EA+D +GWLH+GD+G+  
Sbjct: 443 GKI-LTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLD 501

Query: 571 PAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQP-VAQIYVHGDSLKAFLVGIVVPD 629
             G L +    K I   A GE V P  +E +  +  P ++   + GD LK FL  ++   
Sbjct: 502 GLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLK-FLSMLLTLK 560

Query: 630 PEVMPSWAQK------------RGI---EGTYADLCTNKD--LKKAILEDMVRLGKESGL 672
            E+     +             RG+     T  ++   +D  + KAI + +  + +E+ +
Sbjct: 561 CEMNQMSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVYKAIQQGINAVNQEA-M 619

Query: 673 HSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
           ++ ++++   I    FS+  G L P +K KR  + + +KKQI+ +Y
Sbjct: 620 NNAQRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 111/444 (25%), Positives = 173/444 (38%), Gaps = 104/444 (23%)

Query: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214
           L Q  C+ C        ++ +     N   +++ + A +    V VPLY       + Y+
Sbjct: 78  LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137

Query: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274
           I  +  S V+    Q+ + LL  V RK   G+ L+    P   A+       G V     
Sbjct: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179

Query: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQ 332
                 +E  + PVP Q   +  +++ +TSGTTG PKG + TH N+ A  +G +     +
Sbjct: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVH----K 229

Query: 333 WAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385
           WA T  DV +  LPL H+   +   +     G       +        + LS +   +  
Sbjct: 230 WAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287

Query: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442
            +F  VP +  ++   YD+ F+Q   P  +  L    + K                    
Sbjct: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324

Query: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501
                     +R++V+G+A     VL   +   G  + E YG TE     +   T     
Sbjct: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374

Query: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541
            G VG PLP   +++V  E     AC                    + EGE+ VRGP+VF
Sbjct: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433

Query: 542 KGYLKDPDRTKEALDSDGWLHTGD 565
           + Y   P+ TK A   DGW  TGD
Sbjct: 434 REYWNKPEETKSAFTLDGWFKTGD 457


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 111/444 (25%), Positives = 173/444 (38%), Gaps = 104/444 (23%)

Query: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214
           L Q  C+ C        ++ +     N   +++ + A +    V VPLY       + Y+
Sbjct: 78  LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137

Query: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274
           I  +  S V+    Q+ + LL  V RK   G+ L+    P   A+       G V     
Sbjct: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179

Query: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQ 332
                 +E  + PVP Q   +  +++ +TSGTTG PKG + TH N+ A  +G +     +
Sbjct: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVH----K 229

Query: 333 WAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385
           WA T  DV +  LPL H+   +   +     G       +        + LS +   +  
Sbjct: 230 WAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287

Query: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442
            +F  VP +  ++   YD+ F+Q   P  +  L    + K                    
Sbjct: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324

Query: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501
                     +R++V+G+A     VL   +   G  + E YG TE     +   T     
Sbjct: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374

Query: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541
            G VG PLP   +++V  E     AC                    + EGE+ VRGP+VF
Sbjct: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433

Query: 542 KGYLKDPDRTKEALDSDGWLHTGD 565
           + Y   P+ TK A   DGW  TGD
Sbjct: 434 REYWNKPEETKSAFTLDGWFKTGD 457


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 5/163 (3%)

Query: 457 VTGAAPASPTVLGFLRAALGCQ-VYEGYGQTECTAGCTFTTPGDWT---SGHVGAPLPCN 512
           V   +PA P ++  +   +  + +   YG TE +       P D     +  VG  +P  
Sbjct: 381 VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHT 440

Query: 513 HIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPA 572
             +++++E          GE+C+RG  V  GY  +P +T+EA+D D W  TGD+      
Sbjct: 441 EARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQ 500

Query: 573 GTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHG 615
           G  KI+ R K +  +  GE + P ++E+ +     V ++ V G
Sbjct: 501 GFCKIVGRSKDMI-IRGGENIYPAELEDFFHTHPKVQEVQVVG 542



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 14/185 (7%)

Query: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205
           L++ ++ +  +   SGLL  +   C    +G++  N   W++++LA     +++V +   
Sbjct: 100 LTFAQLKEEVDKAASGLL--SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157

Query: 206 LGPGAIRYIINTADISTVIVDKPQKA-----VL--LLEHVERKETPGLKLIILMDPFEEA 258
                + Y++       ++  K  K      VL  +   VE  +   LK   L D     
Sbjct: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217

Query: 259 LKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ----PDDLSIVCFTSGTTGNPKGAMLT 314
             +      +++  + A     Q   Q     Q     D ++I  FTSGTTG+PKGA L+
Sbjct: 218 SVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQ-FTSGTTGSPKGATLS 276

Query: 315 HGNVV 319
           H N+V
Sbjct: 277 HYNIV 281


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 15/179 (8%)

Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
           VT      P  L   RA  G  + E YGQTE    C  +       G++G    C  +++
Sbjct: 335 VTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQI 394

Query: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571
           +D ++ N      EG+I +R        +F GY+ +PD+T   +  D WL  GD G    
Sbjct: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDE 452

Query: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
            G  + + R   I   + G  + P ++EN  +    V +         V G+ +KAF+V
Sbjct: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
           +++E+++ ++   + +L   C       + V     PEW +V L C    ++ +P     
Sbjct: 82  NFRELSENSQ-QAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMP----- 135

Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
             G I+  + + DI   +     KA++  + V ++      E P L++ +L+        
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185

Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
              + C   +   + + +    +H      Q  + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 15/179 (8%)

Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
           + G     P  L   RA  G  + E YGQTE    C  +       G++G    C  +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394

Query: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571
           +D ++ N      EG+I +R        +F GY+++PD+T   +  D WL  GD G    
Sbjct: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDE 452

Query: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
            G  + + R   I   + G  + P ++EN  ++   V +         V G+ +KAF++
Sbjct: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
           +++E+++ ++   + +L   C       + V     PEW +V L C    ++ +P     
Sbjct: 82  NFRELSENSQ-QAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135

Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
             G I+  + + DI   +     KA++  + V ++      E P L++ +L+        
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185

Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
              + C   +   + + +    +H      Q  + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 15/179 (8%)

Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
           + G     P  L   RA  G  + E YGQTE    C  +       G++G    C  +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394

Query: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571
           +D ++ N      EG+I +R        +F GY+++PD+T   +  D WL  GD G    
Sbjct: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDE 452

Query: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
            G  + + R   I   + G  + P ++EN  ++   V +         V G+ +KAF++
Sbjct: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
           +++E+++ ++   + +L   C       + V     PEW +V L C    ++ +P     
Sbjct: 82  NFRELSENSQ-QAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135

Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
             G I+  + + DI   +     KA++  + V ++      E P L++ +L+        
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185

Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
              + C   +   + + +    +H      Q  + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 56/201 (27%), Positives = 88/201 (43%), Gaps = 15/201 (7%)

Query: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494
           +++  L  N I +     ++  V+   P +P V    R   G  +YEGYGQTE    C  
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387

Query: 495 TTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRG-PN----VFKGYLKDPD 549
                   G +G P P   +K+VDV   N      EG+I ++  PN    +F  Y+ +P 
Sbjct: 388 FKGMKIKPGSMGKPSPAFDVKIVDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPS 446

Query: 550 RTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVA 609
           +T   L  + ++ TGD G     G    + R   +  L+ G  + P ++EN       VA
Sbjct: 447 KTASTLRGNFYI-TGDRGYMDKDGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVA 504

Query: 610 QIYV-------HGDSLKAFLV 623
           +  V        G+ +KAF+V
Sbjct: 505 ESAVVSSPDPIRGEVVKAFVV 525



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)

Query: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187
           +KP  P  W    + +E+    E LGS       +L   C       + +     PEW +
Sbjct: 76  KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135

Query: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246
             +AC     V++P    L    I Y + ++  + +I +      +  + V  K E    
Sbjct: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193

Query: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306
           KLI+      E  +E       ++K       C +  H        +++  + FTSGT+G
Sbjct: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240

Query: 307 NPKGAMLTHGN 317
            PK    TH +
Sbjct: 241 YPKMTAHTHSS 251


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 50/183 (27%), Positives = 82/183 (44%), Gaps = 15/183 (8%)

Query: 453 VRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCN 512
           +R  +TG  P +P VL   R   G ++YEGYGQTE    C      +   G +G  +   
Sbjct: 340 LRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPY 399

Query: 513 HIKLVDVEELNYWACKGEGEICVR-GPN----VFKGYLKDPDRTKEALDSDGWLHTGDIG 567
            ++++D E  N      EGEI +R  P      F  Y+ +P +T   +  D ++ TGD G
Sbjct: 400 DVQIID-ENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYV-TGDRG 457

Query: 568 KWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQI-------YVHGDSLKA 620
                G    + R   +  ++ G  + P ++E+  I    V +         + G+ +KA
Sbjct: 458 VMDSDGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKA 516

Query: 621 FLV 623
           F+V
Sbjct: 517 FVV 519



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 20/152 (13%)

Query: 175 IGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDK---PQKA 231
           + V     PEW +V +AC    ++ +P    L    I Y +  +    ++  +   P   
Sbjct: 117 LAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVE 176

Query: 232 VLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ 291
            ++LE       P LK  +L+ P         Q     + S Q +     E H       
Sbjct: 177 SIVLE------CPDLKTKLLVSP---------QSWNGWL-SFQELFQFASEEHSCVETGS 220

Query: 292 PDDLSIVCFTSGTTGNPKGAMLTHGNVVADFS 323
            + ++I  FTSGTTG PK A  +  ++   F+
Sbjct: 221 QEPMTIY-FTSGTTGFPKMAQHSQSSLGIGFT 251


>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 15/183 (8%)

Query: 453 VRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCN 512
           +R  +TG    +P V    +   G ++YEGYGQ+E    C         SG +G   P  
Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399

Query: 513 HIKLVDVEELNYWACKGEGEICVR-GPN----VFKGYLKDPDRTKEALDSDGWLHTGDIG 567
            +++VD +E N      EG + VR  P      F  YL +P++T  +   D ++ TGD  
Sbjct: 400 DVQIVD-DEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYI-TGDRA 457

Query: 568 KWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYV-------HGDSLKA 620
           +    G    + R   +   +    + P ++E+       V +  V        G+ +KA
Sbjct: 458 RMDKDGYFWFMGRNDDVIN-SSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKA 516

Query: 621 FLV 623
           F+V
Sbjct: 517 FIV 519



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 45/221 (20%), Positives = 88/221 (39%), Gaps = 35/221 (15%)

Query: 100 IGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWL---------SYQE 150
           I  G QL+  Y++ A  +  V+ R L  +G+ P      P   + W+         S++E
Sbjct: 42  ISLGRQLVPEYFNFAHDVLDVWSR-LEEAGHRP------PNPAFWWVNGTGAEIKWSFEE 94

Query: 151 VADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGA 210
           +  ++    + +L   C       + +     PEW +V +AC     V++P    L    
Sbjct: 95  LGKQSR-KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKD 153

Query: 211 IRYIINTADISTVIVDKPQKAVLLLEHVE--RKETPGLKLIILMDPFEEALKERGQKCGV 268
           ++Y +  +   ++I         L   V+    E P L+  +L+    ++ +        
Sbjct: 154 LKYRLQASRAKSIITSDS-----LAPRVDAISAECPSLQTKLLV---SDSSRPGWLNFRE 205

Query: 269 VIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPK 309
           +++      +C +   + P+         + FTSGTTG PK
Sbjct: 206 LLREASTEHNCMRTKSRDPL--------AIYFTSGTTGAPK 238


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 15/176 (8%)

Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
           + G     P  L   RA  G  + E YGQTE    C  +       G++G    C  +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394

Query: 517 VDVEELNYWACKGEGEICVRGPNV--FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGT 574
           +     +  A    G++   G     F G+ ++PD+T   +  D WL  GD G     G 
Sbjct: 395 IAFVHGSPRA----GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGY 449

Query: 575 LKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
            + + R   I   + G  + P ++EN  ++   V +         V G+ +KAF++
Sbjct: 450 FQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
           +++E+++ ++   + +L   C       + V     PEW +V L C    ++ +P     
Sbjct: 82  NFRELSENSQ-QAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135

Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
             G I+  + + DI   +     KA++  + V ++      E P L++ +L+        
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185

Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
              + C   +   + + +    +H      Q  + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 15/176 (8%)

Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
           + G     P  L   RA  G  + E YGQTE    C  +       G++G    C  +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394

Query: 517 VDVEELNYWACKGEGEICVRGPNV--FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGT 574
           +     +  A    G++   G     F G+ ++PD+T   +  D WL  GD G     G 
Sbjct: 395 IAFVHGSPRA----GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGY 449

Query: 575 LKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
            + + R   I   + G  + P ++EN  ++   V +         V G+ +KAF++
Sbjct: 450 FQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
           +++E+++ ++   + +L   C       + V     PEW +V L C    ++ +P     
Sbjct: 82  NFRELSENSQ-QAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135

Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
             G I+  + + DI   +     KA++  + V ++      E P L++ +L+        
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185

Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
              + C   +   + + +    +H      Q  + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 15/160 (9%)

Query: 476 GCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEI-- 533
           G  +YE YGQ+E    C          G +G   P   ++++D ++ +      EG I  
Sbjct: 360 GLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVID-DKGSILPPNTEGNIGI 418

Query: 534 ---CVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQG 590
               VR  ++F  Y  DP++T + ++   + +TGD GK    G +  + R   I   A G
Sbjct: 419 RIKPVRPVSLFMCYEGDPEKTAK-VECGDFYNTGDRGKMDEEGYICFLGRSDDIIN-ASG 476

Query: 591 EYVAPEKIENIYIRSQPVAQIYV-------HGDSLKAFLV 623
             + P ++E+  +    VA+  V        G+ +KAF+V
Sbjct: 477 YRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIV 516



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 41/192 (21%), Positives = 72/192 (37%), Gaps = 26/192 (13%)

Query: 135 GFRKPKQPYQWL---------SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEW 185
           G R P   + W+         S++E+ D    + +   Q  C       + +     PEW
Sbjct: 66  GKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQ-TCGLQQGDHLALMLPRVPEW 124

Query: 186 IIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVI-VDKPQKAVLLLEHVERKETP 244
            +V + C    ++ +P    L    I Y +  +    ++ +D     V  +      + P
Sbjct: 125 WLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDSIA----SQCP 180

Query: 245 GLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGT 304
            LK  +L+       +E       ++KS      C +     P+        ++ FTSGT
Sbjct: 181 SLKTKLLVSDHS---REGWLDFRSLVKSASPEHTCVKSKTLDPM--------VIFFTSGT 229

Query: 305 TGNPKGAMLTHG 316
           TG PK A  +HG
Sbjct: 230 TGFPKMAKHSHG 241


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 2/105 (1%)

Query: 433 NDSIWDELFFNKIQASLG-GCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAG 491
           N  ++ EL  +K   S     ++  V    P SP V+   +      +YEGYGQTE    
Sbjct: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376

Query: 492 CTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVR 536
           C  +         +G PLP   +++VD E  N      EG I +R
Sbjct: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420


>gi|13325057 solute carrier family 27 (fatty acid transporter),
           member 5 [Homo sapiens]
          Length = 690

 Score = 37.7 bits (86), Expect = 0.038
 Identities = 29/79 (36%), Positives = 39/79 (49%), Gaps = 14/79 (17%)

Query: 286 APVPPQPDDL---------SIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPT 336
           AP  P P DL         ++  +TSGTTG PK A+LTH  V+   S  L ++      T
Sbjct: 271 APSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLS----GAT 325

Query: 337 CADVHISYLPLAHMFERMV 355
             DV  + LPL H+   +V
Sbjct: 326 ADDVVYTVLPLYHVMGLVV 344


>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
           sapiens]
          Length = 438

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 23/82 (28%), Positives = 35/82 (42%)

Query: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494
           +++  L  N I +     ++  V+   P +P V    R   G  +YEGYGQTE    C  
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387

Query: 495 TTPGDWTSGHVGAPLPCNHIKL 516
                   G +G P P   +K+
Sbjct: 388 FKGMKIKPGSMGKPSPAFDVKV 409



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)

Query: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187
           +KP  P  W    + +E+    E LGS       +L   C       + +     PEW +
Sbjct: 76  KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135

Query: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246
             +AC     V++P    L    I Y + ++  + +I +      +  + V  K E    
Sbjct: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193

Query: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306
           KLI+      E  +E       ++K       C +  H        +++  + FTSGT+G
Sbjct: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240

Query: 307 NPKGAMLTHGN 317
            PK    TH +
Sbjct: 241 YPKMTAHTHSS 251


>gi|62865631 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 50/229 (21%), Positives = 83/229 (36%), Gaps = 43/229 (18%)

Query: 137 RKPKQPY-----QWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELA 191
           R+P++P+        +YQ+V  R+  +    L H+     D  + +   N P+++ V   
Sbjct: 66  RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124

Query: 192 CYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIIL 251
                 VV  L   +   ++   I       ++V                   G  L+  
Sbjct: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVV-------------------GADLLGT 165

Query: 252 MDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVC---------FTS 302
           ++    +L E     G+     Q V    ++   +P  P P    +V          FTS
Sbjct: 166 VEEILPSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTS 225

Query: 303 GTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISY--LPLAH 349
           GTTG PK A+++   V       L+ +   WA  C    I Y  LPL H
Sbjct: 226 GTTGLPKAAVISQLQV-------LRGSAVLWAFGCTAHDIVYITLPLYH 267


>gi|13325055 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 50/229 (21%), Positives = 83/229 (36%), Gaps = 43/229 (18%)

Query: 137 RKPKQPY-----QWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELA 191
           R+P++P+        +YQ+V  R+  +    L H+     D  + +   N P+++ V   
Sbjct: 66  RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124

Query: 192 CYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIIL 251
                 VV  L   +   ++   I       ++V                   G  L+  
Sbjct: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVV-------------------GADLLGT 165

Query: 252 MDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVC---------FTS 302
           ++    +L E     G+     Q V    ++   +P  P P    +V          FTS
Sbjct: 166 VEEILPSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTS 225

Query: 303 GTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISY--LPLAH 349
           GTTG PK A+++   V       L+ +   WA  C    I Y  LPL H
Sbjct: 226 GTTGLPKAAVISQLQV-------LRGSAVLWAFGCTAHDIVYITLPLYH 267


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 33.1 bits (74), Expect = 0.93
 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 16/80 (20%)

Query: 289 PPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVH---ISY- 344
           P    D  +  FTSGTTG PK A ++H          LK+ + Q       VH   + Y 
Sbjct: 323 PQSITDTCLYIFTSGTTGLPKAARISH----------LKILQCQGFYQLCGVHQEDVIYL 372

Query: 345 -LPLAHMFERMVQSVVYCHG 363
            LPL HM   ++  +V C G
Sbjct: 373 ALPLYHMSGSLL-GIVGCMG 391


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,049,590
Number of Sequences: 37866
Number of extensions: 1369094
Number of successful extensions: 2700
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2587
Number of HSP's gapped (non-prelim): 57
length of query: 722
length of database: 18,247,518
effective HSP length: 110
effective length of query: 612
effective length of database: 14,082,258
effective search space: 8618341896
effective search space used: 8618341896
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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