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Search of human proteins with 134244291
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134244291 G-protein coupled receptor 37 like 1 [Homo
sapiens]
(481 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens] 990 0.0
gi|4885323 G protein-coupled receptor 37 [Homo sapiens] 421 e-118
gi|169808392 endothelin receptor type B isoform 1 precursor [Hom... 130 3e-30
gi|4557547 endothelin receptor type B isoform 1 precursor [Homo ... 130 3e-30
gi|4503465 endothelin receptor type A [Homo sapiens] 129 5e-30
gi|4503467 endothelin receptor type B isoform 2 precursor [Homo ... 119 8e-27
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 96 6e-20
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 96 6e-20
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 90 5e-18
gi|161484640 neuromedin B receptor [Homo sapiens] 86 1e-16
gi|222080109 orexin receptor 2 [Homo sapiens] 82 8e-16
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 81 2e-15
gi|222080095 orexin receptor 1 [Homo sapiens] 75 1e-13
gi|5174595 melatonin receptor 1B [Homo sapiens] 74 2e-13
gi|4503905 galanin receptor 2 [Homo sapiens] 74 4e-13
gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 70 4e-12
gi|5174593 melatonin receptor 1A [Homo sapiens] 70 4e-12
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 67 4e-11
gi|31083315 G protein-coupled receptor 45 [Homo sapiens] 66 8e-11
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 66 8e-11
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 65 1e-10
gi|20373179 G protein-coupled receptor 73 [Homo sapiens] 65 2e-10
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 64 2e-10
gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom... 63 5e-10
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 63 5e-10
gi|4502607 cholecystokinin A receptor [Homo sapiens] 63 5e-10
gi|188497623 neuromedin U receptor 1 [Homo sapiens] 62 9e-10
gi|149944554 somatostatin receptor 4 [Homo sapiens] 62 1e-09
gi|5453796 neuropeptide Y receptor Y5 [Homo sapiens] 62 1e-09
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 62 2e-09
>gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens]
Length = 481
Score = 990 bits (2559), Expect = 0.0
Identities = 481/481 (100%), Positives = 481/481 (100%)
Query: 1 MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYV 60
MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYV
Sbjct: 1 MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYV 60
Query: 61 PEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPL 120
PEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPL
Sbjct: 61 PEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPL 120
Query: 121 YPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVL 180
YPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVL
Sbjct: 121 YPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVL 180
Query: 181 FFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVR 240
FFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVR
Sbjct: 181 FFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVR 240
Query: 241 PIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYS 300
PIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYS
Sbjct: 241 PIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYS 300
Query: 301 LVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNST 360
LVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNST
Sbjct: 301 LVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNST 360
Query: 361 VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCIC 420
VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCIC
Sbjct: 361 VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCIC 420
Query: 421 RPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTP 480
RPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTP
Sbjct: 421 RPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTP 480
Query: 481 C 481
C
Sbjct: 481 C 481
>gi|4885323 G protein-coupled receptor 37 [Homo sapiens]
Length = 613
Score = 421 bits (1083), Expect = e-118
Identities = 205/401 (51%), Positives = 283/401 (70%), Gaps = 8/401 (1%)
Query: 84 ATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAV 143
A + N G + G RGN T +R++++NP YP+T+ SY AYA+M L++V+F
Sbjct: 218 ALAQNGSLGEGIHEPGGPRRGNSTN---RRVRLKNPFYPLTQESYGAYAVMCLSVVIFGT 274
Query: 144 GIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSC 203
GI+GNL+VMCIV H+YY++S NS+LA+LA WDFL++FFCLP+VIF+E+TK+ LL D SC
Sbjct: 275 GIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSC 334
Query: 204 RAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLA 263
+ VP++EV+SLGVTTF+LCAL IDRF AT+ IE C S AKLAVIWVG++ LA
Sbjct: 335 KIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLA 394
Query: 264 VPELLLWQLAQEPAPTMG--TLDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLP 321
+PE++L QL++E G + CI+K S LP+++Y L +TY +AR+WWYFGCYFCLP
Sbjct: 395 LPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLP 454
Query: 322 ILFTVTCQLVTWRVRGPPGRKSECRASKHE-QCESQLNSTVVGLTVVYAFCTLPENVCNI 380
LFT+TC LVT R + K+ R +K + Q ESQ+N TVV LT++Y FC +PEN+CNI
Sbjct: 455 TLFTITCSLVTAR-KIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNI 513
Query: 381 VVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECG 440
V AY++T +++QT+DLL +I+QF FFK +TPVLL C+C+P +AF++ CCCCCCEEC
Sbjct: 514 VTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCKPFSRAFME-CCCCCCEECI 572
Query: 441 GASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC 481
S ++ +DN+ TE+ S + RE +GT C
Sbjct: 573 QKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC 613
>gi|169808392 endothelin receptor type B isoform 1 precursor [Homo
sapiens]
Length = 442
Score = 130 bits (327), Expect = 3e-30
Identities = 110/439 (25%), Positives = 191/439 (43%), Gaps = 60/439 (13%)
Query: 11 LAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRP 70
+A++LA GLSR+ G +RG + A + Q AE P
Sbjct: 13 VALVLACGLSRIWG-------------------EERGFPPDRATPLLQT-----AEIMTP 48
Query: 71 IHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSA 130
PTK L N + G+P + + P+
Sbjct: 49 -------PTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFK 101
Query: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190
Y +++ +VF +GI+GN +++ I++ + +++ N ++ASLAL D L + +PI ++
Sbjct: 102 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK 161
Query: 191 EITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILA 250
+ + G C+ VPF++ +S+G+T SLCAL IDR+ A ++ +++ I +
Sbjct: 162 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYR-AVASWSRIKGIGVPKWTAV 220
Query: 251 KLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARM 310
++ +IWV S+ LAVPE + + + L C++ P + + Y+ A+
Sbjct: 221 EIVLIWVVSVVLAVPEAIGFDIITMDYKG-SYLRICLLHPVQKT-----AFMQFYKTAKD 274
Query: 311 WWYFGCYFCLPILFT------VTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGL 364
WW F YFCLP+ T +TC++ +R G + + H + ++ TV L
Sbjct: 275 WWLFSFYFCLPLAITAFFYTLMTCEM----LRKKSG--MQIALNDHLKQRREVAKTVFCL 328
Query: 365 TVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGL--------INQFSTFFKGAITPVLL 416
+V+A C LP ++ I+ L + +LL IN S I P+ L
Sbjct: 329 VLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMAS--LNSCINPIAL 386
Query: 417 LCICRPLGQAFLDCCCCCC 435
+ + F C CC C
Sbjct: 387 YLVSKRFKNCFKSCLCCWC 405
>gi|4557547 endothelin receptor type B isoform 1 precursor [Homo
sapiens]
Length = 442
Score = 130 bits (327), Expect = 3e-30
Identities = 110/439 (25%), Positives = 191/439 (43%), Gaps = 60/439 (13%)
Query: 11 LAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRP 70
+A++LA GLSR+ G +RG + A + Q AE P
Sbjct: 13 VALVLACGLSRIWG-------------------EERGFPPDRATPLLQT-----AEIMTP 48
Query: 71 IHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSA 130
PTK L N + G+P + + P+
Sbjct: 49 -------PTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFK 101
Query: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190
Y +++ +VF +GI+GN +++ I++ + +++ N ++ASLAL D L + +PI ++
Sbjct: 102 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK 161
Query: 191 EITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILA 250
+ + G C+ VPF++ +S+G+T SLCAL IDR+ A ++ +++ I +
Sbjct: 162 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYR-AVASWSRIKGIGVPKWTAV 220
Query: 251 KLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARM 310
++ +IWV S+ LAVPE + + + L C++ P + + Y+ A+
Sbjct: 221 EIVLIWVVSVVLAVPEAIGFDIITMDYKG-SYLRICLLHPVQKT-----AFMQFYKTAKD 274
Query: 311 WWYFGCYFCLPILFT------VTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGL 364
WW F YFCLP+ T +TC++ +R G + + H + ++ TV L
Sbjct: 275 WWLFSFYFCLPLAITAFFYTLMTCEM----LRKKSG--MQIALNDHLKQRREVAKTVFCL 328
Query: 365 TVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGL--------INQFSTFFKGAITPVLL 416
+V+A C LP ++ I+ L + +LL IN S I P+ L
Sbjct: 329 VLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMAS--LNSCINPIAL 386
Query: 417 LCICRPLGQAFLDCCCCCC 435
+ + F C CC C
Sbjct: 387 YLVSKRFKNCFKSCLCCWC 405
>gi|4503465 endothelin receptor type A [Homo sapiens]
Length = 427
Score = 129 bits (325), Expect = 5e-30
Identities = 82/318 (25%), Positives = 152/318 (47%), Gaps = 23/318 (7%)
Query: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190
Y +++ +F VG+VGN +++ I++ + +++ N+++ASLAL D + + LPI +F
Sbjct: 81 YINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFK 140
Query: 191 EIT-----KQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERC 245
+ G C+ PF++ SS+G+T +LCAL +DR+ A ++ +V+ I
Sbjct: 141 LLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYR-AVASWSRVQGIGIP 199
Query: 246 QSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTL-DSCIMKPSASLPESLYSLVMT 304
++ IW+ S LA+PE + + + P G +C++ ++ E
Sbjct: 200 LVTAIEIVSIWILSFILAIPEAIGFVMV--PFEYRGEQHKTCMLNATSKFME-------F 250
Query: 305 YQNARMWWYFGCYFCLPILFT-VTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVG 363
YQ+ + WW FG YFC+P++ T + L+T + S+H + ++ TV
Sbjct: 251 YQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFC 310
Query: 364 LTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFS------TFFKGAITPVLLL 417
L V++A C P ++ I+ + E+ + +LL + I P+ L
Sbjct: 311 LVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALY 370
Query: 418 CICRPLGQAFLDCCCCCC 435
+ + F C CCCC
Sbjct: 371 FVSKKFKNCFQSCLCCCC 388
>gi|4503467 endothelin receptor type B isoform 2 precursor [Homo
sapiens]
Length = 436
Score = 119 bits (297), Expect = 8e-27
Identities = 99/396 (25%), Positives = 178/396 (44%), Gaps = 50/396 (12%)
Query: 11 LAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRP 70
+A++LA GLSR+ G +RG + A + Q AE P
Sbjct: 13 VALVLACGLSRIWG-------------------EERGFPPDRATPLLQT-----AEIMTP 48
Query: 71 IHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSA 130
PTK L N + G+P + + P+
Sbjct: 49 -------PTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFK 101
Query: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190
Y +++ +VF +GI+GN +++ I++ + +++ N ++ASLAL D L + +PI ++
Sbjct: 102 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK 161
Query: 191 EITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILA 250
+ + G C+ VPF++ +S+G+T SLCAL IDR+ A ++ +++ I +
Sbjct: 162 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYR-AVASWSRIKGIGVPKWTAV 220
Query: 251 KLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARM 310
++ +IWV S+ LAVPE + + + L C++ P + + Y+ A+
Sbjct: 221 EIVLIWVVSVVLAVPEAIGFDIITMDYKG-SYLRICLLHPVQKT-----AFMQFYKTAKD 274
Query: 311 WWYFGCYFCLPILFT------VTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGL 364
WW F YFCLP+ T +TC++ +R G + + H + ++ TV L
Sbjct: 275 WWLFSFYFCLPLAITAFFYTLMTCEM----LRKKSG--MQIALNDHLKQRREVAKTVFCL 328
Query: 365 TVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLI 400
+V+A C LP ++ I+ L + +LL +
Sbjct: 329 VLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFL 364
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 96.3 bits (238), Expect = 6e-20
Identities = 70/306 (22%), Positives = 135/306 (44%), Gaps = 8/306 (2%)
Query: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190
Y I + V+ +G++GN++++ I +++ N ++SLAL D L+L C P+
Sbjct: 41 YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 100
Query: 191 EITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILA 250
+ + L G + C+ +PF++++S+GV+ F+L AL DR+ + ++ I
Sbjct: 101 YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPM-DIQASHALMKICL 159
Query: 251 KLAVIWVGSMTLAVPELLLWQLAQ-EPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNAR 309
K A IW+ SM LA+PE + L T T SC P ++ L+ + + +
Sbjct: 160 KAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSN---ELHPKIHSMASFL 216
Query: 310 MWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYA 369
+++ + + L+ P + K + +L TV+ ++A
Sbjct: 217 VFYVIPLSIISVYYYFIAKNLIQSAYNLPV--EGNIHVKKQIESRKRLAKTVLVFVGLFA 274
Query: 370 FCTLPENVCNIVVAYLSTELTRQTLDLL-GLINQFSTFFKGAITPVLLLCICRPLGQAFL 428
FC LP +V + +Y +E+ L + + + F + P L + + + F
Sbjct: 275 FCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFN 334
Query: 429 DCCCCC 434
CC
Sbjct: 335 TQLLCC 340
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 96.3 bits (238), Expect = 6e-20
Identities = 70/306 (22%), Positives = 135/306 (44%), Gaps = 8/306 (2%)
Query: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190
Y I + V+ +G++GN++++ I +++ N ++SLAL D L+L C P+
Sbjct: 25 YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 84
Query: 191 EITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILA 250
+ + L G + C+ +PF++++S+GV+ F+L AL DR+ + ++ I
Sbjct: 85 YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPM-DIQASHALMKICL 143
Query: 251 KLAVIWVGSMTLAVPELLLWQLAQ-EPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNAR 309
K A IW+ SM LA+PE + L T T SC P ++ L+ + + +
Sbjct: 144 KAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSN---ELHPKIHSMASFL 200
Query: 310 MWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYA 369
+++ + + L+ P + K + +L TV+ ++A
Sbjct: 201 VFYVIPLSIISVYYYFIAKNLIQSAYNLPV--EGNIHVKKQIESRKRLAKTVLVFVGLFA 258
Query: 370 FCTLPENVCNIVVAYLSTELTRQTLDLL-GLINQFSTFFKGAITPVLLLCICRPLGQAFL 428
FC LP +V + +Y +E+ L + + + F + P L + + + F
Sbjct: 259 FCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFN 318
Query: 429 DCCCCC 434
CC
Sbjct: 319 TQLLCC 324
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 89.7 bits (221), Expect = 5e-18
Identities = 73/320 (22%), Positives = 143/320 (44%), Gaps = 31/320 (9%)
Query: 132 AIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNE 191
AI + V+ +VGI+GN ++ + + + +++ N + SLA D L+L C+P+ +
Sbjct: 49 AIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHY 108
Query: 192 ITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAK 251
+ + L G + C+ + F+ ++S+GV+ F+L L DR+ L + +P K
Sbjct: 109 LAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLER-QPSNAILKTCVK 167
Query: 252 LAVIWVGSMTLAVPELLLWQL--AQEPAPTMGTLDSCIMKP-SASLPESLYSLVMTYQNA 308
+W+ SM A+PE + + ++P M T +SC P S L + ++SL+
Sbjct: 168 AGCVWIVSMIFALPEAIFSNVYTFRDPNKNM-TFESCTSYPVSKKLLQEIHSLLC----- 221
Query: 309 RMWWYFGCYFCLPI-LFTVTCQLVT---WRVRGPPGRKSECRASKHEQCESQLNSTVVGL 364
F ++ +P+ + +V L+ ++ + + A K + ++ TV+ L
Sbjct: 222 -----FLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVL 276
Query: 365 TVVYAFCTLPENVCNIVVAYLSTELTRQTL-------DLLGLINQFSTFFKGAITPVLLL 417
++A C LP + + YL T QT + + ++ F + P L
Sbjct: 277 VALFALCWLPNH-----LLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALY 331
Query: 418 CICRPLGQAFLDCCCCCCCE 437
+ + + F CC E
Sbjct: 332 WLSKSFQKHFKAQLFCCKAE 351
>gi|161484640 neuromedin B receptor [Homo sapiens]
Length = 390
Score = 85.5 bits (210), Expect = 1e-16
Identities = 67/305 (21%), Positives = 135/305 (44%), Gaps = 19/305 (6%)
Query: 136 LALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQ 195
L L++ VG++GN+ ++ I + ++S N +++LA D L+L C+P+ +
Sbjct: 49 LYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDE 108
Query: 196 RLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVI 255
+ G V C+ +P ++++S+GV+ F+L AL DR+ + + ++ K I
Sbjct: 109 WMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPM-DMQTSGALLRTCVKAMGI 167
Query: 256 WVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSA-SLPESLYSLVMTYQNARMWWYF 314
WV S+ LAVPE + ++A+ + + +CI P L ++S+++ F
Sbjct: 168 WVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLI----------F 217
Query: 315 GCYFCLP-----ILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYA 369
YF +P I + + + PG +E K + +L V+ +
Sbjct: 218 LVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNE-HTKKQMETRKRLAKIVLVFVGCFI 276
Query: 370 FCTLPENVCNIVVAYLSTELTRQTLDLL-GLINQFSTFFKGAITPVLLLCICRPLGQAFL 428
FC P ++ + ++ E+ ++ L+ + +F + P L + + F
Sbjct: 277 FCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFN 336
Query: 429 DCCCC 433
CC
Sbjct: 337 SQLCC 341
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 82.4 bits (202), Expect = 8e-16
Identities = 68/336 (20%), Positives = 146/336 (43%), Gaps = 36/336 (10%)
Query: 131 YAIMLLA--LVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVI 188
Y +L+A ++VF V ++GN+ V VW ++++++ N + +L+L D LV CLP +
Sbjct: 53 YEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATL 112
Query: 189 FNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSI 248
+IT+ G C+ +P+++ S+ V+ +L + +DR++ L +R ++
Sbjct: 113 VVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARN- 171
Query: 249 LAKLAVIWVGSMTLAVPELLLWQLAQ-----EPAPTMGTLDSCIMKPSASLPESLYSL-- 301
+ +IW+ S + +P+ ++ + + T+ T+ C + + +Y +
Sbjct: 172 --SIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTV--CDERWGGEIYPKMYHICF 227
Query: 302 -VMTYQN------ARMWWYFGCYFCLPILFTVTCQLVTWRVRGP------PGRKSECRAS 348
++TY F +C I T + W+ P PG+ ++ R S
Sbjct: 228 FLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMS 287
Query: 349 ------KHEQCESQLNSTVVGLTVVYAFCTLPENVCNI---VVAYLSTELTRQTLDLLGL 399
K + + ++ + +V+A C LP ++ N+ V + R+T+
Sbjct: 288 AVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFT 347
Query: 400 INQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCC 435
+ + + A P++ + + F CCC
Sbjct: 348 FSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCC 383
>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
Length = 384
Score = 81.3 bits (199), Expect = 2e-15
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 27/294 (9%)
Query: 133 IMLLALVVFAV---GIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIF 189
I LAL AV G+ GNL+++ I+ +++ N ++ +L+ D LV CLP
Sbjct: 40 IFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFV 99
Query: 190 NEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSIL 249
+ + G+ C+ PF++ S+ V+ FSL + ++R H RP R
Sbjct: 100 YTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVER-HQLIINPRGWRPNNR--HAY 156
Query: 250 AKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMK-------PSASLPESLYSLV 302
+AVIWV ++ ++P L+ + EP + TLD+ K PS S S +L+
Sbjct: 157 VGIAVIWVLAVASSLPFLIYQVMTDEPFQNV-TLDAYKDKYVCFDQFPSDSHRLSYTTLL 215
Query: 303 MTYQNARMWWYFGCYFCLPILFTVTCQLVTW-RVRGPPGRKSECRASKHEQCES-QLNST 360
+ Q YFG P+ F C + R++ + R +K+ E+ ++N
Sbjct: 216 LVLQ------YFG-----PLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIM 264
Query: 361 VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPV 414
++ + V +A C LP + N V + + +LL L+ + + P+
Sbjct: 265 LLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPI 318
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 75.1 bits (183), Expect = 1e-13
Identities = 87/406 (21%), Positives = 162/406 (39%), Gaps = 48/406 (11%)
Query: 86 SPNPGKDGGTPDSGQELRGNLTGAPGQRLQI--QNPLYPVTESSYSAYAIMLLA--LVVF 141
S PG G P +E + L+ ++ LYP Y +L+A + VF
Sbjct: 4 SATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYP------KQYEWVLIAAYVAVF 57
Query: 142 AVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDV 201
V +VGN V VW ++++++ N + +L+L D LV CLP + +IT+ L G
Sbjct: 58 VVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHA 117
Query: 202 SCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQ-SILAKLAVIWVGSM 260
C+ +P+++ S+ V +L + +DR++ L R + SIL IW S+
Sbjct: 118 LCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILG----IWAVSL 173
Query: 261 TLAVPELLLWQLAQ---EPAPTMGTLDSCIMKPSASLPESLYS---LVMTYQNARMWWYF 314
+ VP+ + + + E A C + + L +Y ++TY A +
Sbjct: 174 AIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYL-APLGLMA 232
Query: 315 GCYFCL-------PILFTVTCQLVTWR------------VRGPPGRKSECRASKHEQCES 355
YF + I T + + W+ + G P ++ ++ +Q +
Sbjct: 233 MAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRA 292
Query: 356 QLNSTVVGLTV--VYAFCTLPENVCNI---VVAYLSTELTRQTLDLLGLINQFSTFFKGA 410
+ + + + V V+A C LP +V N+ V R+ + + + + A
Sbjct: 293 RRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSA 352
Query: 411 ITPVLLLCICRPLGQAFLDCCCCCC--CEECGGASEASAANGSDNK 454
P++ + + F CC CG S + + +K
Sbjct: 353 ANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHK 398
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/289 (24%), Positives = 126/289 (43%), Gaps = 24/289 (8%)
Query: 130 AYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIF 189
A A+ + +V AV +VGNL V+ V + L++A N L SLAL D +V F+ P+++
Sbjct: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
Query: 190 NEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSIL 249
LG+ C+A F+ S+ + F++ A+ I+R+ ++ R R + L
Sbjct: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
Query: 250 AKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNAR 309
+ +IW+ ++ +P + L +P + SC +AS + +V+
Sbjct: 160 -HICLIWLLTVVALLPNFFVGSLEYDP-----RIYSCTFIQTASTQYTAAVVVI------ 207
Query: 310 MWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRAS---KHEQCESQLNSTVVGLTV 366
+F LPI C L W + RK++ + K S L VV V
Sbjct: 208 -------HFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVV--FV 258
Query: 367 VYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVL 415
++A C P N + VA E+ Q + L + + +F + ++
Sbjct: 259 IFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIV 307
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 73.6 bits (179), Expect = 4e-13
Identities = 74/349 (21%), Positives = 144/349 (41%), Gaps = 21/349 (6%)
Query: 130 AYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIF 189
A + LL ++F VG VGN V+ ++ S N + +L + D + C+P
Sbjct: 25 AVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQAT 84
Query: 190 NEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSIL 249
+ G + C+AV F+ ++ ++F+L A+ +DR+ L R + ++ L
Sbjct: 85 IYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHS-RELRTPRNAL 143
Query: 250 AKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNAR 309
A + +IW S+ + P L ++ +Q + L C P+ S P + T+
Sbjct: 144 AAIGLIWGLSLLFSGPYLSYYRQSQ-----LANLTVC--HPAWSAPRRRAMDICTF---- 192
Query: 310 MWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYA 369
++ Y L + + T + + WR P S R +K ++ ++ + ++
Sbjct: 193 VFSYLLPVLVLGLTYARTLRYL-WRAVDPVAAGSGARRAKR-----KVTRMILIVAALFC 246
Query: 370 FCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLD 429
C +P + + V + LTR T L +++ ++ + P++ + + + F
Sbjct: 247 LCWMPHHALILCVWFGQFPLTRATY-ALRILSHLVSYANSCVNPIVYALVSKHFRKGFRT 305
Query: 430 CCCCCCCEECGGAS--EASAANGSDNKLKTEVSSSIYFHKPRESPPLLP 476
C G AS +AA G+ + E SS H + L P
Sbjct: 306 ICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRP 354
>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
Length = 398
Score = 70.1 bits (170), Expect = 4e-12
Identities = 79/306 (25%), Positives = 133/306 (43%), Gaps = 45/306 (14%)
Query: 83 VATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFA 142
VATS P G P N +G PG + P + + A+ + L +
Sbjct: 4 VATS-GPNASWGAP-------ANASGCPGCGANASDGPVP-SPRAVDAWLVPLFFAALML 54
Query: 143 VGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVS 202
+G+VGN V+ ++ +++ N +A+LA D L C+P +LGD
Sbjct: 55 LGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFM 114
Query: 203 CRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAV---IWVGS 259
C+ V +++ S+ T +L A+ +DR++V T+ +R + R LA LAV IWVGS
Sbjct: 115 CKFVNYIQQVSVQATCATLTAMSVDRWYV---TVFPLRALHRRTPRLA-LAVSLSIWVGS 170
Query: 260 MTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPE--SLYSLVMTYQNARMWWYFGCY 317
++ P L L +L+ P P ++ PS +L +LY+L+ Y
Sbjct: 171 AAVSAPVLALHRLS--PGPRAYCSEAF---PSRALERAFALYNLLALY------------ 213
Query: 318 FCLPILFTVTCQLVTWR------VRGPP---GRKSECRASKHEQCESQLNSTVVGLTVVY 368
LP+L T C R VR P + + A + ++++ V + +++
Sbjct: 214 -LLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLF 272
Query: 369 AFCTLP 374
A C P
Sbjct: 273 AACWGP 278
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 70.1 bits (170), Expect = 4e-12
Identities = 63/295 (21%), Positives = 127/295 (43%), Gaps = 30/295 (10%)
Query: 127 SYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPI 186
S+ A A+ + + V I+GNL V+ V+ + L++A N + SLA+ D +V + P+
Sbjct: 24 SWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
Query: 187 VIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQ 246
V+ + LG + C+ F+ S+ + F++ + I+R+ +L K + +
Sbjct: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSL-KYDKLYSSK 142
Query: 247 SILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQ 306
+ L + +IW+ ++ +P L L +P + SC S S S Y++ +
Sbjct: 143 NSLCYVLLIWLLTLAAVLPNLRAGTLQYDP-----RIYSCTFAQSVS---SAYTIAVVV- 193
Query: 307 NARMWWYFGCYFCLPILFTVTCQLVTW------RVRGPPGRKSECRASKHEQCESQLNST 360
+F +P++ + C L W R R P RK + + T
Sbjct: 194 ---------FHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNF-----VT 239
Query: 361 VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVL 415
+ + V++A C P N + VA + + + L + + + +F + ++
Sbjct: 240 MFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAII 294
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 67.0 bits (162), Expect = 4e-11
Identities = 59/194 (30%), Positives = 94/194 (48%), Gaps = 9/194 (4%)
Query: 88 NPGKDGGTPDSGQELRGNLTGA--PGQRLQIQNPLYPVTESSYS-AYAIMLLALVVFAVG 144
NP D G S G L A G N P + + + + ++L A ++FA
Sbjct: 2 NPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFA-- 59
Query: 145 IVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCR 204
IVGN+ V+ V + +L++ N + +LA+ D L+ F LP E+ +LG + C
Sbjct: 60 IVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCD 119
Query: 205 AVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAV 264
++V + SLCA+ IDR+ +L + R ++ILA L+V WV S +++
Sbjct: 120 IWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSV-WVLSTVISI 178
Query: 265 PELLLWQLAQEPAP 278
LL W +EPAP
Sbjct: 179 GPLLGW---KEPAP 189
>gi|31083315 G protein-coupled receptor 45 [Homo sapiens]
Length = 372
Score = 65.9 bits (159), Expect = 8e-11
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 24/267 (8%)
Query: 132 AIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNE 191
++ ++ L++ VG +GN V IV+ ++SA N +LA+LA D ++ C+P
Sbjct: 36 SLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTL 95
Query: 192 ITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAK 251
IT + GD CR + + L + +DRF + K+ P R + I
Sbjct: 96 ITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNP-RRAKVI--- 151
Query: 252 LAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMW 311
+AV WV S +A P L W L + PA C++ + + Y V+T A +
Sbjct: 152 IAVSWVLSFCIAGPSLTGWTLVEVPA----RAPQCVLGYTELPADRAY--VVTLVVAVFF 205
Query: 312 WYFGCYFCLPILFTVTCQLVTWRVRGPPG--------RKSECRASKHEQCESQLN----- 358
FG C + T + RV R R + +Q L+
Sbjct: 206 APFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKA 265
Query: 359 -STVVGLTVVYAFCTLPENVCNIVVAY 384
+T++ L V ++ C LP +V +++ +
Sbjct: 266 FTTILILFVGFSLCWLPHSVYSLLSVF 292
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 65.9 bits (159), Expect = 8e-11
Identities = 36/143 (25%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 132 AIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNE 191
A++L +++FA+ + GN V +V S +++ N + SLAL D L+ FFC+P+ +
Sbjct: 47 ALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQN 106
Query: 192 ITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAK 251
I+ L G C+ VPF++ +++ ++ + ++R H K++ +
Sbjct: 107 ISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVER-HQGLVHPFKMKWQYTNRRAFTM 165
Query: 252 LAVIWVGSMTLAVPELLLWQLAQ 274
L V+W+ ++ + P +W + Q
Sbjct: 166 LGVVWLVAVIVGSP---MWHVQQ 185
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 65.1 bits (157), Expect = 1e-10
Identities = 64/273 (23%), Positives = 116/273 (42%), Gaps = 27/273 (9%)
Query: 109 APGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSI 168
APG PL V ++ Y + + L+V G++GNL+V+ S L++ N
Sbjct: 49 APGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMF 108
Query: 169 LASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDR 228
+ +LA+ DFL+ F P+ + + KQ L G+ C F + +L A+ +DR
Sbjct: 109 IINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDR 168
Query: 229 FHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIM 288
+ V T L + ++ L V W+ ++ ++P W A P G L SC
Sbjct: 169 YLVITRPLATFGVASKRRAAFVLLGV-WLYALAWSLPPFFGWS-AYVPE---GLLTSCSW 223
Query: 289 KPSASLPE-SLYSLVMTYQNARMWWYFGCY-FCLPILFTVTCQLVTWRVRGPPGRKSE-- 344
+ P Y++++ C+ F LP+L + C + +R GR +
Sbjct: 224 DYMSFTPAVRAYTMLLC-----------CFVFFLPLLIIIYCYIFIFRAIRETGRALQTF 272
Query: 345 --CRAS-----KHEQCESQLNSTVVGLTVVYAF 370
C+ + + ++ +S+ + L V+ F
Sbjct: 273 GACKGNGESLWQRQRLQSECKMAKIMLLVILLF 305
>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
Length = 393
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/272 (22%), Positives = 118/272 (43%), Gaps = 20/272 (7%)
Query: 128 YSAYAIMLLALV-VFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPI 186
++A ++ +ALV + V +GN + + L++ N ++A+LA+ DFLV C P
Sbjct: 59 FAAKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPF 118
Query: 187 VIFNEITKQRLL--GDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIER 244
+ + +Q G V C +V ++ SL V+T +L A+ IDR+ + + +RP +
Sbjct: 119 EMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRY---LAIVHPLRPRMK 175
Query: 245 CQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSL-VM 303
CQ+ +A++W S+ +A+P T T+ + ++ +
Sbjct: 176 CQTATGLIALVWTVSILIAIPSAYF---------TTETVLVIVKSQEKIFCGQIWPVDQQ 226
Query: 304 TYQNARMWWYFGCYFCLPILFTVTCQLVTWR---VRGPPGRKSECRASKHEQCESQLNST 360
Y + + FG F P++ C R + PG ++E + K +C +
Sbjct: 227 LYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTE-QIRKRLRCRRKTVLV 285
Query: 361 VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQ 392
++ + Y C P IV + T ++
Sbjct: 286 LMCILTAYVLCWAPFYGFTIVRDFFPTVFVKE 317
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 64.3 bits (155), Expect = 2e-10
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 7/183 (3%)
Query: 96 PDSGQEL---RGNLTGAPGQRLQIQNPLYPVTES-SYSAYAIMLLALVVFAVGIVGNLSV 151
P +G E + NL+ AP Q ++ +Y + S + +MLLAL+ A + N V
Sbjct: 12 PPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTL-SNAFV 70
Query: 152 MCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEV 211
+ V+ + L + N ++ASLA+ D LV +PI +T + LG V C ++
Sbjct: 71 IATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDI 130
Query: 212 SSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQ 271
+ + LC + +DR+ T + + + +A++WV S+++++P W+
Sbjct: 131 TCCTASILHLCVIALDRYWAITDAV-EYSAKRTPKRAAVMIALVWVFSISISLPP-FFWR 188
Query: 272 LAQ 274
A+
Sbjct: 189 QAK 191
>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
sapiens]
Length = 366
Score = 63.2 bits (152), Expect = 5e-10
Identities = 70/286 (24%), Positives = 125/286 (43%), Gaps = 22/286 (7%)
Query: 138 LVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQR- 196
+ +F VGI GNL M +V L++ N L+S+A D L++F C+P+ + + + R
Sbjct: 51 VALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSD-LLIFLCMPLDLV-RLWQYRP 108
Query: 197 -LLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVI 255
GD+ C+ F+ S T ++ AL ++R+ L + + + + + VI
Sbjct: 109 WNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPL-RAKVVVTKGRVKLVIFVI 167
Query: 256 WVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMWWYFG 315
W + A P +L + E + C +P+ S VM + ++ ++F
Sbjct: 168 WAVAFCSAGPIFVLVGVEHENGTDPWDTNEC--RPTEFAVRSGLLTVMVWVSS--IFFFL 223
Query: 316 CYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAF--CTL 373
FCL +L+++ + + R RG + R H+Q L VV+AF C L
Sbjct: 224 PVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKML------AVVVFAFILCWL 277
Query: 374 PENVCNIVVAYL----STELTRQTLDLLGLINQFSTFFKGAITPVL 415
P +V + + S E+ Q L++ + AI P+L
Sbjct: 278 PFHVGRYLFSKSFEPGSLEIA-QISQYCNLVSFVLFYLSAAINPIL 322
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 63.2 bits (152), Expect = 5e-10
Identities = 43/190 (22%), Positives = 84/190 (44%), Gaps = 14/190 (7%)
Query: 86 SPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGI 145
SP G + +P + E GN TG + SY +LL ++F +
Sbjct: 5 SPGQGNNTTSPPAPFETGGNTTGISDVTV------------SYQVITSLLLGTLIFCA-V 51
Query: 146 VGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRA 205
+GN V+ + L++ N ++ SLA+ D +V LP+ ++ + LG V+C
Sbjct: 52 LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDL 111
Query: 206 VPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVP 265
++V + LCA+ +DR+ T + V + A +++ W+ +++P
Sbjct: 112 FIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNK-RTPRRAAALISLTWLIGFLISIP 170
Query: 266 ELLLWQLAQE 275
+L W+ ++
Sbjct: 171 PMLGWRTPED 180
>gi|4502607 cholecystokinin A receptor [Homo sapiens]
Length = 428
Score = 63.2 bits (152), Expect = 5e-10
Identities = 38/171 (22%), Positives = 82/171 (47%), Gaps = 2/171 (1%)
Query: 134 MLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEIT 193
+LL ++F + ++GN V+ ++ + +++ N L SLA+ D ++ FC+P + +
Sbjct: 45 ILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLL 104
Query: 194 KQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLA 253
K + G C+ + +S+ V+TF+L A+ ++R+ L + R + L +A
Sbjct: 105 KDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPL-QSRVWQTKSHALKVIA 163
Query: 254 VIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSC-IMKPSASLPESLYSLVM 303
W S T+ P + L T + C + P+ + +S ++ ++
Sbjct: 164 ATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLL 214
>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
Length = 426
Score = 62.4 bits (150), Expect = 9e-10
Identities = 76/322 (23%), Positives = 133/322 (41%), Gaps = 36/322 (11%)
Query: 138 LVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQR- 196
L++F VG VGN ++ +++ N L SLA+ D LVL LP+ ++
Sbjct: 68 LLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPF 127
Query: 197 LLGDVSC--RAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAV 254
LLG C R + F V V ++ AL ++R+ L + R + L
Sbjct: 128 LLGVGGCYFRTLLFEMVCLASV--LNVTALSVERYVAVVHPLQARSMVTRAH-VRRVLGA 184
Query: 255 IWVGSMTLAVPELLLWQLAQEPAPTMGTL-DSCIMKPSASLPESLYSLVMTYQNARMWWY 313
+W +M ++P L + Q P G + DS + P +LY++V+ Q +
Sbjct: 185 VWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVC--MLVRPRALYNMVV--QTTAL--- 237
Query: 314 FGCYFCLPI-LFTVTCQLVTWRV-------------RGPPGRKSE--CRASKHEQCESQL 357
+FCLP+ + +V L+ R+ RG +S CR +H++ Q+
Sbjct: 238 --LFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQV 295
Query: 358 NSTVVGLTVVYAFCTLPENVCNIVVAYLS--TELTRQTLDLLGLINQFSTFFKGAITPVL 415
+ L VV+ C P + ++ + +S T+ + +I+ + A PVL
Sbjct: 296 TKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVL 355
Query: 416 LLCICRPLGQAFLDCCC--CCC 435
+ + F + C CC
Sbjct: 356 YSLMSSRFRETFQEALCLGACC 377
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 62.0 bits (149), Expect = 1e-09
Identities = 74/316 (23%), Positives = 133/316 (42%), Gaps = 26/316 (8%)
Query: 132 AIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNE 191
AI + +V VG+VGN V+ ++ +K+A N L +LA+ D L + +P V +
Sbjct: 49 AIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFM-LSVPFVASSA 107
Query: 192 ITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAK 251
+ G V CRAV ++ ++ + F L L +DR+ + + +R + +AK
Sbjct: 108 ALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRY---VAVVHPLRAATYRRPSVAK 164
Query: 252 L--AVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNAR 309
L +W+ S+ + +P + A T + + P +S V
Sbjct: 165 LINLGVWLASLLVTLPIAIF-------ADTRPARGGQAVACNLQWPHPAWSAVFVV---- 213
Query: 310 MWWYFGCYFCLPILFTVTCQ-LVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVY 368
+ F F LP+L C L+ ++R R + + E ++ V+ + VV+
Sbjct: 214 --YTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAG---WQQRRRSEKKITRLVLMVVVVF 268
Query: 369 AFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFL 428
C +P V ++ ++++ T++ + LI ++ I L R Q L
Sbjct: 269 VLCWMPFYVVQLLNLFVTS--LDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVL 326
Query: 429 DCCCCCCCEECGGASE 444
C CC E GGA E
Sbjct: 327 -CLRCCLLEGAGGAEE 341
>gi|5453796 neuropeptide Y receptor Y5 [Homo sapiens]
Length = 445
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/228 (21%), Positives = 92/228 (40%), Gaps = 6/228 (2%)
Query: 119 PLYPVTESSYSAYAIMLLALVVFA--VGIVGNLSVMCIVWHSYYLKSAWNSILASLALWD 176
P++ +SS L+ L F +G +GNL ++ + K+ N ++ +LA D
Sbjct: 28 PVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSD 87
Query: 177 FLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTL 236
LV+ FC P + + + Q + G V C +PF++ S+ V+T L ++ I R+H+ +
Sbjct: 88 ILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPI 147
Query: 237 PKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPE 296
+ +A +W + P + L + L S S P
Sbjct: 148 SNNLTANHGYFL---IATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPS 204
Query: 297 SLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSE 344
Y + T + + Y CL + T C+ ++ + R E
Sbjct: 205 DSYRIAFTI-SLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEE 251
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 61.6 bits (148), Expect = 2e-09
Identities = 64/253 (25%), Positives = 108/253 (42%), Gaps = 19/253 (7%)
Query: 133 IMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEI 192
I+LL VV VG+VGN ++ ++ L + N ++ +LAL D L+ C+P+ +
Sbjct: 63 IVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAF 122
Query: 193 TKQR-LLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAK 251
+ + G C V F++ ++ V+ F+L + +DR+ V P R I S A
Sbjct: 123 EPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVH--PLRRRISLRLSAYAV 180
Query: 252 LAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMW 311
LA IW S LA+P + T + L E + + W
Sbjct: 181 LA-IWALSAVLALP------------AAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAW 227
Query: 312 WYFGCYFCLPILFTVTCQL---VTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVY 368
+ LP+L + + V R R PG ++ +A + +V + VV+
Sbjct: 228 GLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVF 287
Query: 369 AFCTLPENVCNIV 381
A C LP +V N++
Sbjct: 288 AVCWLPLHVFNLL 300
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,067,705
Number of Sequences: 37866
Number of extensions: 965917
Number of successful extensions: 4916
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 264
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 4376
Number of HSP's gapped (non-prelim): 495
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.