Guide to the Human Genome
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Search of human proteins with 55770862

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55770862 thyroglobulin [Homo sapiens]
         (2768 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55770862 thyroglobulin [Homo sapiens]                             5696   0.0  
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa...   237   1e-61
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa...   234   7e-61
gi|4557351 butyrylcholinesterase precursor [Homo sapiens]             220   2e-56
gi|51593088 neuroligin 3 [Homo sapiens]                               193   2e-48
gi|31317256 X-linked neuroligin 4 [Homo sapiens]                      193   2e-48
gi|24308209 X-linked neuroligin 4 [Homo sapiens]                      193   2e-48
gi|40538788 neuroligin 4, Y-linked [Homo sapiens]                     189   2e-47
gi|30840978 neuroligin 2 [Homo sapiens]                               189   2e-47
gi|33563374 carboxylesterase 3 [Homo sapiens]                         185   6e-46
gi|7662470 neuroligin 1 [Homo sapiens]                                182   4e-45
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]               177   2e-43
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]               177   2e-43
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]              166   3e-40
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]           157   1e-37
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]     155   5e-37
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]     155   5e-37
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]     155   5e-37
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]               154   1e-36
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]             138   9e-32
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]             95   1e-18
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]             95   1e-18
gi|144953895 nidogen 2 precursor [Homo sapiens]                        89   5e-17
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]     79   8e-14
gi|78190498 secreted modular calcium-binding protein 1 isoform 1...    75   9e-13
gi|11545873 secreted modular calcium-binding protein 1 isoform 2...    75   9e-13
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]             73   3e-12
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]      59   7e-08
gi|115298674 nidogen 1 precursor [Homo sapiens]                        58   1e-07
gi|93141003 testican 3 isoform 1 [Homo sapiens]                        54   3e-06

>gi|55770862 thyroglobulin [Homo sapiens]
          Length = 2768

 Score = 5696 bits (14776), Expect = 0.0
 Identities = 2768/2768 (100%), Positives = 2768/2768 (100%)

Query: 1    MALVLEIFTLLASICWVSANIFEYQVDAQPLRPCELQRETAFLKQADYVPQCAEDGSFQT 60
            MALVLEIFTLLASICWVSANIFEYQVDAQPLRPCELQRETAFLKQADYVPQCAEDGSFQT
Sbjct: 1    MALVLEIFTLLASICWVSANIFEYQVDAQPLRPCELQRETAFLKQADYVPQCAEDGSFQT 60

Query: 61   VQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGYINSTDTSYLPQC 120
            VQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGYINSTDTSYLPQC
Sbjct: 61   VQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGYINSTDTSYLPQC 120

Query: 121  QDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRSCEIRNRRLLHGVGDKSP 180
            QDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRSCEIRNRRLLHGVGDKSP
Sbjct: 121  QDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRSCEIRNRRLLHGVGDKSP 180

Query: 181  PQCSAEGEFMPVQCKFVNTTDMMIFDLVHSYNRFPDAFVTFSSFQRRFPEVSGYCHCADS 240
            PQCSAEGEFMPVQCKFVNTTDMMIFDLVHSYNRFPDAFVTFSSFQRRFPEVSGYCHCADS
Sbjct: 181  PQCSAEGEFMPVQCKFVNTTDMMIFDLVHSYNRFPDAFVTFSSFQRRFPEVSGYCHCADS 240

Query: 241  QGRELAETGLELLLDEIYDTIFAGLDLPSTFTETTLYRILQRRFLAVQSVISGRFRCPTK 300
            QGRELAETGLELLLDEIYDTIFAGLDLPSTFTETTLYRILQRRFLAVQSVISGRFRCPTK
Sbjct: 241  QGRELAETGLELLLDEIYDTIFAGLDLPSTFTETTLYRILQRRFLAVQSVISGRFRCPTK 300

Query: 301  CEVERFTATSFGHPYVPSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHGTRQQGEPPSCAE 360
            CEVERFTATSFGHPYVPSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHGTRQQGEPPSCAE
Sbjct: 301  CEVERFTATSFGHPYVPSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHGTRQQGEPPSCAE 360

Query: 361  GQSCASERQQALSRLYFGTSGYFSQHDLFSSPEKRWASPRVARFATSCPPTIKELFVDSG 420
            GQSCASERQQALSRLYFGTSGYFSQHDLFSSPEKRWASPRVARFATSCPPTIKELFVDSG
Sbjct: 361  GQSCASERQQALSRLYFGTSGYFSQHDLFSSPEKRWASPRVARFATSCPPTIKELFVDSG 420

Query: 421  LLRPMVEGQSQQFSVSENLLKEAIRAIFPSRGLARLALQFTTNPKRLQQNLFGGKFLVNV 480
            LLRPMVEGQSQQFSVSENLLKEAIRAIFPSRGLARLALQFTTNPKRLQQNLFGGKFLVNV
Sbjct: 421  LLRPMVEGQSQQFSVSENLLKEAIRAIFPSRGLARLALQFTTNPKRLQQNLFGGKFLVNV 480

Query: 481  GQFNLSGALGTRGTFNFSQFFQQLGLASFLNGGRQEDLAKPLSVGLDSNSSTGTPEAAKK 540
            GQFNLSGALGTRGTFNFSQFFQQLGLASFLNGGRQEDLAKPLSVGLDSNSSTGTPEAAKK
Sbjct: 481  GQFNLSGALGTRGTFNFSQFFQQLGLASFLNGGRQEDLAKPLSVGLDSNSSTGTPEAAKK 540

Query: 541  DGTMNKPTVGSFGFEINLQENQNALKFLASLLELPEFLLFLQHAISVPEDVARDLGDVME 600
            DGTMNKPTVGSFGFEINLQENQNALKFLASLLELPEFLLFLQHAISVPEDVARDLGDVME
Sbjct: 541  DGTMNKPTVGSFGFEINLQENQNALKFLASLLELPEFLLFLQHAISVPEDVARDLGDVME 600

Query: 601  TVLSSQTCEQTPERLFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQPRCPT 660
            TVLSSQTCEQTPERLFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQPRCPT
Sbjct: 601  TVLSSQTCEQTPERLFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQPRCPT 660

Query: 661  DCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAI 720
            DCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAI
Sbjct: 661  DCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAI 720

Query: 721  GKPKKCPTPCQLQSEQAFLRTVQALLSNSSMLPTLSDTYIPQCSTDGQWRQVQCNGPPEQ 780
            GKPKKCPTPCQLQSEQAFLRTVQALLSNSSMLPTLSDTYIPQCSTDGQWRQVQCNGPPEQ
Sbjct: 721  GKPKKCPTPCQLQSEQAFLRTVQALLSNSSMLPTLSDTYIPQCSTDGQWRQVQCNGPPEQ 780

Query: 781  VFELYQRWEAQNKGQDLTPAKLLVKIMSYREAASGNFSLFIQSLYEAGQQDVFPVLSQYP 840
            VFELYQRWEAQNKGQDLTPAKLLVKIMSYREAASGNFSLFIQSLYEAGQQDVFPVLSQYP
Sbjct: 781  VFELYQRWEAQNKGQDLTPAKLLVKIMSYREAASGNFSLFIQSLYEAGQQDVFPVLSQYP 840

Query: 841  SLQDVPLAALEGKRPQPRENILLEPYLFWQILNGQLSQYPGSYSDFSTPLAHFDLRNCWC 900
            SLQDVPLAALEGKRPQPRENILLEPYLFWQILNGQLSQYPGSYSDFSTPLAHFDLRNCWC
Sbjct: 841  SLQDVPLAALEGKRPQPRENILLEPYLFWQILNGQLSQYPGSYSDFSTPLAHFDLRNCWC 900

Query: 901  VDEAGQELEGMRSEPSKLPTCPGSCEEAKLRVLQFIRETEEIVSASNSSRFPLGESFLVA 960
            VDEAGQELEGMRSEPSKLPTCPGSCEEAKLRVLQFIRETEEIVSASNSSRFPLGESFLVA
Sbjct: 901  VDEAGQELEGMRSEPSKLPTCPGSCEEAKLRVLQFIRETEEIVSASNSSRFPLGESFLVA 960

Query: 961  KGIRLRNEDLGLPPLFPPREAFAEQFLRGSDYAIRLAAQSTLSFYQRRRFSPDDSAGASA 1020
            KGIRLRNEDLGLPPLFPPREAFAEQFLRGSDYAIRLAAQSTLSFYQRRRFSPDDSAGASA
Sbjct: 961  KGIRLRNEDLGLPPLFPPREAFAEQFLRGSDYAIRLAAQSTLSFYQRRRFSPDDSAGASA 1020

Query: 1021 LLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKS 1080
            LLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKS
Sbjct: 1021 LLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKS 1080

Query: 1081 RTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSS 1140
            RTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSS
Sbjct: 1081 RTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSS 1140

Query: 1141 SSAQCPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPG 1200
            SSAQCPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPG
Sbjct: 1141 SSAQCPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPG 1200

Query: 1201 TRVTGGQPACESPRCPLPFNASEVVGGTILCETISGPTGSAMQQCQLLCRQGSWSVFPPG 1260
            TRVTGGQPACESPRCPLPFNASEVVGGTILCETISGPTGSAMQQCQLLCRQGSWSVFPPG
Sbjct: 1201 TRVTGGQPACESPRCPLPFNASEVVGGTILCETISGPTGSAMQQCQLLCRQGSWSVFPPG 1260

Query: 1261 PLICSLESGRWESQLPQPRACQRPQLWQTIQTQGHFQLQLPPGKMCSADYADLLQTFQVF 1320
            PLICSLESGRWESQLPQPRACQRPQLWQTIQTQGHFQLQLPPGKMCSADYADLLQTFQVF
Sbjct: 1261 PLICSLESGRWESQLPQPRACQRPQLWQTIQTQGHFQLQLPPGKMCSADYADLLQTFQVF 1320

Query: 1321 ILDELTARGFCQIQVKTFGTLVSIPVCNNSSVQVGCLTRERLGVNVTWKSRLEDIPVASL 1380
            ILDELTARGFCQIQVKTFGTLVSIPVCNNSSVQVGCLTRERLGVNVTWKSRLEDIPVASL
Sbjct: 1321 ILDELTARGFCQIQVKTFGTLVSIPVCNNSSVQVGCLTRERLGVNVTWKSRLEDIPVASL 1380

Query: 1381 PDLHDIERALVGKDLLGRFTDLIQSGSFQLHLDSKTFPAETIRFLQGDHFGTSPRTWFGC 1440
            PDLHDIERALVGKDLLGRFTDLIQSGSFQLHLDSKTFPAETIRFLQGDHFGTSPRTWFGC
Sbjct: 1381 PDLHDIERALVGKDLLGRFTDLIQSGSFQLHLDSKTFPAETIRFLQGDHFGTSPRTWFGC 1440

Query: 1441 SEGFYQVLTSEASQDGLGCVKCPEGSYSQDEECIPCPVGFYQEQAGSLACVPCPVGRTTI 1500
            SEGFYQVLTSEASQDGLGCVKCPEGSYSQDEECIPCPVGFYQEQAGSLACVPCPVGRTTI
Sbjct: 1441 SEGFYQVLTSEASQDGLGCVKCPEGSYSQDEECIPCPVGFYQEQAGSLACVPCPVGRTTI 1500

Query: 1501 SAGAFSQTHCVTDCQRNEAGLQCDQNGQYRASQKDRGSGKAFCVDGEGRRLPWWETEAPL 1560
            SAGAFSQTHCVTDCQRNEAGLQCDQNGQYRASQKDRGSGKAFCVDGEGRRLPWWETEAPL
Sbjct: 1501 SAGAFSQTHCVTDCQRNEAGLQCDQNGQYRASQKDRGSGKAFCVDGEGRRLPWWETEAPL 1560

Query: 1561 EDSQCLMMQKFEKVPESKVIFDANAPVAVRSKVPDSEFPVMQCLTDCTEDEACSFFTVST 1620
            EDSQCLMMQKFEKVPESKVIFDANAPVAVRSKVPDSEFPVMQCLTDCTEDEACSFFTVST
Sbjct: 1561 EDSQCLMMQKFEKVPESKVIFDANAPVAVRSKVPDSEFPVMQCLTDCTEDEACSFFTVST 1620

Query: 1621 TEPEISCDFYAWTSDNVACMTSDQKRDALGNSKATSFGSLRCQVKVRSHGQDSPAVYLKK 1680
            TEPEISCDFYAWTSDNVACMTSDQKRDALGNSKATSFGSLRCQVKVRSHGQDSPAVYLKK
Sbjct: 1621 TEPEISCDFYAWTSDNVACMTSDQKRDALGNSKATSFGSLRCQVKVRSHGQDSPAVYLKK 1680

Query: 1681 GQGSTTTLQKRFEPTGFQNMLSGLYNPIVFSASGANLTDAHLFCLLACDRDLCCDGFVLT 1740
            GQGSTTTLQKRFEPTGFQNMLSGLYNPIVFSASGANLTDAHLFCLLACDRDLCCDGFVLT
Sbjct: 1681 GQGSTTTLQKRFEPTGFQNMLSGLYNPIVFSASGANLTDAHLFCLLACDRDLCCDGFVLT 1740

Query: 1741 QVQGGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIK 1800
            QVQGGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIK
Sbjct: 1741 QVQGGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIK 1800

Query: 1801 SLTPLEGTQDTFTNFQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVD 1860
            SLTPLEGTQDTFTNFQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVD
Sbjct: 1801 SLTPLEGTQDTFTNFQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVD 1860

Query: 1861 LNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFCQLAEITESASLYFTCT 1920
            LNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFCQLAEITESASLYFTCT
Sbjct: 1861 LNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFCQLAEITESASLYFTCT 1920

Query: 1921 LYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRN 1980
            LYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRN
Sbjct: 1921 LYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRN 1980

Query: 1981 KVPMSEKSISNGFFECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENG 2040
            KVPMSEKSISNGFFECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENG
Sbjct: 1981 KVPMSEKSISNGFFECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENG 2040

Query: 2041 GAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSLTEKVSLDSWQSLALSS 2100
            GAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSLTEKVSLDSWQSLALSS
Sbjct: 2041 GAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSLTEKVSLDSWQSLALSS 2100

Query: 2101 VVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADT 2160
            VVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADT
Sbjct: 2101 VVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADT 2160

Query: 2161 QSCTHSLQGQNCRLLLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGT 2220
            QSCTHSLQGQNCRLLLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGT
Sbjct: 2161 QSCTHSLQGQNCRLLLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGT 2220

Query: 2221 SWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSED 2280
            SWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSED
Sbjct: 2221 SWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSED 2280

Query: 2281 CLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVF 2340
            CLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVF
Sbjct: 2281 CLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVF 2340

Query: 2341 GFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTAR 2400
            GFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTAR
Sbjct: 2341 GFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTAR 2400

Query: 2401 ATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPAN 2460
            ATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPAN
Sbjct: 2401 ATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPAN 2460

Query: 2461 VLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRA 2520
            VLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRA
Sbjct: 2461 VLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRA 2520

Query: 2521 KAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRAL 2580
            KAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRAL
Sbjct: 2521 KAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRAL 2580

Query: 2581 ENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAY 2640
            ENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAY
Sbjct: 2581 ENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAY 2640

Query: 2641 EGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEF 2700
            EGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEF
Sbjct: 2641 EGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEF 2700

Query: 2701 SELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQE 2760
            SELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQE
Sbjct: 2701 SELLPNRQGLKKADCSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQE 2760

Query: 2761 PGSKTYSK 2768
            PGSKTYSK
Sbjct: 2761 PGSKTYSK 2768


>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
            sapiens]
          Length = 614

 Score =  237 bits (604), Expect = 1e-61
 Identities = 171/549 (31%), Positives = 269/549 (48%), Gaps = 48/549 (8%)

Query: 2211 GRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQ--- 2266
            GR + I++ T    V  FLG+P+A PP+  RRF  PEP   W+G  DA+  ++ C+Q   
Sbjct: 46   GRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVD 105

Query: 2267 ------PGTRT-STSPGVSEDCLYLNVFIPQNVAPNAS-VLVFFHNTMDREESEGWPAID 2318
                   GT   + +  +SEDCLYLNV+ P     + + VLV+ +       +      D
Sbjct: 106  TLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYD 165

Query: 2319 GSFLAAVGNLIVVTASYRVGVFGFLS-SGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 2377
            G FL      ++V+ +YRVG FGFL+  GS E  GN GLLDQ  AL WVQ ++  FGGDP
Sbjct: 166  GRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDP 225

Query: 2378 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALA 2437
              V+L  +  GA    +HLL+  +    LF RAVL  G+   P A +    A+++A  LA
Sbjct: 226  TSVTLFGESAGAASVGMHLLSPPSRG--LFHRAVLQSGAPNGPWATVGMGEARRRATQLA 283

Query: 2438 KEVSCPM----SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPP 2492
              V CP      +  E+V+CLR +PA VL + +  +L     F + + PV+DG FL + P
Sbjct: 284  HLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTP 343

Query: 2493 ARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDS 2552
               +    +  + +L+G  +D+G          F +      S+  F   ++  +  + S
Sbjct: 344  EALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGV-PQVS 402

Query: 2553 DARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMA---SAWAKRARGNVF 2609
            D   EA    Y    H  +D A    AL +   D+ ++CP+  +A   +A   R    VF
Sbjct: 403  DLAAEAVVLHYTDWLH-PEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVF 461

Query: 2610 MYHAPE-------NYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHF 2662
             + A            HG      +++F  G+P  P+    ++ EEK  + ++M+Y+++F
Sbjct: 462  EHRASTLSWPLWMGVPHG-----YEIEFIFGIPLDPS--RNYTAEEKIFAQRLMRYWANF 514

Query: 2663 IRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFS-ELLPNRQGLKKADCSFWSKY 2721
             R+G+PN P +        A  WP +   AG + Y       L  R+GL+   C+FW+++
Sbjct: 515  ARTGDPNEPRD------PKAPQWPPYT--AGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566

Query: 2722 ISSLKTSAD 2730
            +  L ++ D
Sbjct: 567  LPKLLSATD 575


>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
            sapiens]
          Length = 617

 Score =  234 bits (598), Expect = 7e-61
 Identities = 170/544 (31%), Positives = 266/544 (48%), Gaps = 48/544 (8%)

Query: 2211 GRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQ--- 2266
            GR + I++ T    V  FLG+P+A PP+  RRF  PEP   W+G  DA+  ++ C+Q   
Sbjct: 46   GRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVD 105

Query: 2267 ------PGTRT-STSPGVSEDCLYLNVFIPQNVAPNAS-VLVFFHNTMDREESEGWPAID 2318
                   GT   + +  +SEDCLYLNV+ P     + + VLV+ +       +      D
Sbjct: 106  TLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYD 165

Query: 2319 GSFLAAVGNLIVVTASYRVGVFGFLS-SGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 2377
            G FL      ++V+ +YRVG FGFL+  GS E  GN GLLDQ  AL WVQ ++  FGGDP
Sbjct: 166  GRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDP 225

Query: 2378 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALA 2437
              V+L  +  GA    +HLL+  +    LF RAVL  G+   P A +    A+++A  LA
Sbjct: 226  TSVTLFGESAGAASVGMHLLSPPSRG--LFHRAVLQSGAPNGPWATVGMGEARRRATQLA 283

Query: 2438 KEVSCPM----SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPP 2492
              V CP      +  E+V+CLR +PA VL + +  +L     F + + PV+DG FL + P
Sbjct: 284  HLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTP 343

Query: 2493 ARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDS 2552
               +    +  + +L+G  +D+G          F +      S+  F   ++  +  + S
Sbjct: 344  EALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGV-PQVS 402

Query: 2553 DARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMA---SAWAKRARGNVF 2609
            D   EA    Y    H  +D A    AL +   D+ ++CP+  +A   +A   R    VF
Sbjct: 403  DLAAEAVVLHYTDWLH-PEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVF 461

Query: 2610 MYHAPE-------NYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHF 2662
             + A            HG      +++F  G+P  P+    ++ EEK  + ++M+Y+++F
Sbjct: 462  EHRASTLSWPLWMGVPHG-----YEIEFIFGIPLDPS--RNYTAEEKIFAQRLMRYWANF 514

Query: 2663 IRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFS-ELLPNRQGLKKADCSFWSKY 2721
             R+G+PN P +        A  WP +   AG + Y       L  R+GL+   C+FW+++
Sbjct: 515  ARTGDPNEPRD------PKAPQWPPYT--AGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566

Query: 2722 ISSL 2725
            +  L
Sbjct: 567  LPKL 570


>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
          Length = 602

 Score =  220 bits (560), Expect = 2e-56
 Identities = 161/540 (29%), Positives = 256/540 (47%), Gaps = 48/540 (8%)

Query: 2206 HGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASC 2264
            +G++ G +  +  GT    V  FLG+PYA PPL   RF+ P+ L  W+  W+A+K   SC
Sbjct: 38   NGKVRGMNLTVFGGT----VTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSC 93

Query: 2265 WQ------PGTRTST----SPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGW 2314
             Q      PG   S     +  +SEDCLYLNV+IP     NA+VL++ +    +  +   
Sbjct: 94   CQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSL 153

Query: 2315 PAIDGSFLAAVGNLIVVTASYRVGVFGFLS-SGSGEVSGNWGLLDQVAALTWVQTHIRGF 2373
               DG FLA V  +IVV+ +YRVG  GFL+  G+ E  GN GL DQ  AL WVQ +I  F
Sbjct: 154  HVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAF 213

Query: 2374 GGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQA 2433
            GG+P+ V+L  +  GA   S+HLL+    +  LF RA+L  GS  +P AV S   A+ + 
Sbjct: 214  GGNPKSVTLFGESAGAASVSLHLLS--PGSHSLFTRAILQSGSFNAPWAVTSLYEARNRT 271

Query: 2434 IALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPP 2492
            + LAK   C   +  E++ CLR K    +   +  ++    P    +GP +DG FL + P
Sbjct: 272  LNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMP 331

Query: 2493 ARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDS 2552
               L+   + +  +L+G ++D+G          F +      ++  F + L+    G   
Sbjct: 332  DILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSE 391

Query: 2553 DARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYH 2612
              +   +  ++Y+         ++  AL +   DY  ICP ++    +++      F Y 
Sbjct: 392  FGK--ESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYF 449

Query: 2613 A--------PENYG--HGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHF 2662
                     PE  G  HG      +++F  GLP        ++  E+ LS  I++ +++F
Sbjct: 450  EHRSSKLPWPEWMGVMHG-----YEIEFVFGLPL--ERRDNYTKAEEILSRSIVKRWANF 502

Query: 2663 IRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEF-SELLPNRQGLKKADCSFWSKY 2721
             + GNPN       +    +T WP F  ++  + Y    +E       L+   C FW+ +
Sbjct: 503  AKYGNPN-------ETQNNSTSWPVF--KSTEQKYLTLNTESTRIMTKLRAQQCRFWTSF 553


>gi|51593088 neuroligin 3 [Homo sapiens]
          Length = 828

 Score =  193 bits (491), Expect = 2e-48
 Identities = 161/540 (29%), Positives = 248/540 (45%), Gaps = 79/540 (14%)

Query: 2192 LSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPL-N 2250
            L      P+  ++TH   L  ++          VDQ+LGVPYAAPP+ E+RF  PEP  +
Sbjct: 33   LRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPS 92

Query: 2251 WTGSWDASKPRASCWQPGTRTSTSPGV--------------------SEDCLYLNVFIP- 2289
            W+G  +A+     C  P    +  P V                    +EDCLYLNV++P 
Sbjct: 93   WSGIRNATHFPPVC--PQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPT 150

Query: 2290 ----------QNVAPNAS-------------VLVFFHNTMDREESEGWPAIDGSFLAAVG 2326
                      +++A N               V+V+ H     E +     IDGS LA+ G
Sbjct: 151  EDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNM--IDGSILASYG 208

Query: 2327 NLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADR 2386
            N+IV+T +YRVGV GFLS+G     GN+GLLDQ+ AL WV  +I  FGGDPRR+++    
Sbjct: 209  NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 268

Query: 2387 GGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSS 2446
             GA   S  LLT    +  LF+RA++  GSALS  AV  + +  +    LA +V C +  
Sbjct: 269  IGASCVS--LLTLSHHSEGLFQRAIIQSGSALSSWAV--NYQPVKYTSLLADKVGCNVLD 324

Query: 2447 SQEVVSCLRQKPANVL--NDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEV 2504
            + ++V CLRQK A  L   D Q     V+     +GPVIDG  + + P   +++  ++  
Sbjct: 325  TVDMVDCLRQKSAKELVEQDIQPARYHVA-----FGPVIDGDVIPDDPEILMEQGEFLNY 379

Query: 2505 DLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYY 2564
            D+++G +Q +GL    + V   E+    T    +    + N  G  +    +     + Y
Sbjct: 380  DIMLGVNQGEGL-KFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMY 438

Query: 2565 SLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYH--------AP 2614
            +     D+  +  + L     D+  + P +  A   A+      F   YH        A 
Sbjct: 439  TDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAW 498

Query: 2615 ENYGHGSLELLADVQFALGLPFY---PAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYP 2671
             +  HG      +V +  G+P       +   FS  +  LS  +M Y+++F ++G+PN P
Sbjct: 499  SDAAHGD-----EVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKP 553


>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
          Length = 816

 Score =  193 bits (490), Expect = 2e-48
 Identities = 142/481 (29%), Positives = 233/481 (48%), Gaps = 45/481 (9%)

Query: 2225 VDQFLGVPYAAPPLAERRFQAPEP-LNWTGSWDASKPRASCWQP---------------- 2267
            V+Q+LGVPYA+PP  ERRFQ PEP  +WTG  + ++  A C Q                 
Sbjct: 70   VEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFT 129

Query: 2268 ---GTRTSTSPGVSEDCLYLNVFIP-----QNVAPNASVLVFFHNTMDREESEGWPAIDG 2319
                T  +     +EDCLYLN+++P      +      V+V+ H     E +     IDG
Sbjct: 130  ANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNM--IDG 187

Query: 2320 SFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRR 2379
            S LA+ GN+IV+T +YR+G+ GFLS+G     GN+GLLDQ+ AL W++ ++  FGGDP+R
Sbjct: 188  SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 2380 VSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKE 2439
            V++     GA   S  LLT    +  LF++A++  G+ALS  AV +++ A+   I LA +
Sbjct: 248  VTIFGSGAGASCVS--LLTLSHYSEGLFQKAIIQSGTALSSWAV-NYQPAKYTRI-LADK 303

Query: 2440 VSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPPARALKR 2498
            V C M  + ++V CLR K    L     +       +H  +GPVIDG  + + P   +++
Sbjct: 304  VGCNMLDTTDMVECLRNKNYKEL----IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQ 359

Query: 2499 SLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEA 2558
              ++  D+++G +Q +GL      +   E+         +    + N  G  +    +  
Sbjct: 360  GEFLNYDIMLGVNQGEGL-KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE 418

Query: 2559 AATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYHAPEN 2616
               + Y+     ++  +  + L     D+  + P +  A   A+      F   YH  ++
Sbjct: 419  TIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS 478

Query: 2617 YGHGSLELLA---DVQFALGLPFY---PAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNY 2670
                S    A   +V +  G+P       +   FS  +  LS  +M Y+++F ++G+PN 
Sbjct: 479  EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ 538

Query: 2671 P 2671
            P
Sbjct: 539  P 539


>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
          Length = 816

 Score =  193 bits (490), Expect = 2e-48
 Identities = 142/481 (29%), Positives = 233/481 (48%), Gaps = 45/481 (9%)

Query: 2225 VDQFLGVPYAAPPLAERRFQAPEP-LNWTGSWDASKPRASCWQP---------------- 2267
            V+Q+LGVPYA+PP  ERRFQ PEP  +WTG  + ++  A C Q                 
Sbjct: 70   VEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFT 129

Query: 2268 ---GTRTSTSPGVSEDCLYLNVFIP-----QNVAPNASVLVFFHNTMDREESEGWPAIDG 2319
                T  +     +EDCLYLN+++P      +      V+V+ H     E +     IDG
Sbjct: 130  ANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNM--IDG 187

Query: 2320 SFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRR 2379
            S LA+ GN+IV+T +YR+G+ GFLS+G     GN+GLLDQ+ AL W++ ++  FGGDP+R
Sbjct: 188  SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 2380 VSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKE 2439
            V++     GA   S  LLT    +  LF++A++  G+ALS  AV +++ A+   I LA +
Sbjct: 248  VTIFGSGAGASCVS--LLTLSHYSEGLFQKAIIQSGTALSSWAV-NYQPAKYTRI-LADK 303

Query: 2440 VSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPPARALKR 2498
            V C M  + ++V CLR K    L     +       +H  +GPVIDG  + + P   +++
Sbjct: 304  VGCNMLDTTDMVECLRNKNYKEL----IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQ 359

Query: 2499 SLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEA 2558
              ++  D+++G +Q +GL      +   E+         +    + N  G  +    +  
Sbjct: 360  GEFLNYDIMLGVNQGEGL-KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE 418

Query: 2559 AATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYHAPEN 2616
               + Y+     ++  +  + L     D+  + P +  A   A+      F   YH  ++
Sbjct: 419  TIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS 478

Query: 2617 YGHGSLELLA---DVQFALGLPFY---PAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNY 2670
                S    A   +V +  G+P       +   FS  +  LS  +M Y+++F ++G+PN 
Sbjct: 479  EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ 538

Query: 2671 P 2671
            P
Sbjct: 539  P 539


>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
          Length = 816

 Score =  189 bits (481), Expect = 2e-47
 Identities = 141/481 (29%), Positives = 232/481 (48%), Gaps = 45/481 (9%)

Query: 2225 VDQFLGVPYAAPPLAERRFQAPE-PLNWTGSWDASKPRASCWQP---------------- 2267
            V+Q+LGVPYA+PP  ERRFQ PE P +WTG  +A++  A C Q                 
Sbjct: 70   VEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFT 129

Query: 2268 ---GTRTSTSPGVSEDCLYLNVFIPQN-----VAPNASVLVFFHNTMDREESEGWPAIDG 2319
                T  +     +EDCLYLN+++P             V+V+ H     E +     IDG
Sbjct: 130  TSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNM--IDG 187

Query: 2320 SFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRR 2379
            S LA+ GN+IV+T + R+G+ GFLS+G     GN+GLLDQ+ AL W++ ++  FGGDP+R
Sbjct: 188  SILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247

Query: 2380 VSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKE 2439
            V++     GA   S  LLT    +  LF++A++  G+ALS  AV +++ A+   I LA +
Sbjct: 248  VTIFGSGAGASCVS--LLTLSHYSEGLFQKAIIQSGTALSSWAV-NYQPAKYTRI-LADK 303

Query: 2440 VSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPPARALKR 2498
            V C M  + ++V CL+ K    L     +       +H  +GPVIDG  + + P   +++
Sbjct: 304  VGCNMLDTTDMVECLKNKNYKEL----IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQ 359

Query: 2499 SLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEA 2558
              ++  D+++G +Q +GL      +   E+         +    + N  G  +    +  
Sbjct: 360  GEFLNYDIMLGVNQGEGL-KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE 418

Query: 2559 AATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYHAPEN 2616
               + Y+     ++  +  + L     D+  + P +  A   A+      F   YH  ++
Sbjct: 419  TIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS 478

Query: 2617 YGHGSLELLA---DVQFALGLPFY---PAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNY 2670
                S    A   +V +  G+P       +   FS  +  LS  +M Y+++F ++G+PN 
Sbjct: 479  EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ 538

Query: 2671 P 2671
            P
Sbjct: 539  P 539


>gi|30840978 neuroligin 2 [Homo sapiens]
          Length = 835

 Score =  189 bits (481), Expect = 2e-47
 Identities = 157/541 (29%), Positives = 241/541 (44%), Gaps = 75/541 (13%)

Query: 2187 PGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAP 2246
            PG+ L S       V  + +GR+ G  + +        V QFLGVPYA PPL  RRFQ P
Sbjct: 29   PGLGLGSLGEERFPVVNTAYGRVRGVRRELN-NEILGPVVQFLGVPYATPPLGARRFQPP 87

Query: 2247 E-PLNWTGSWDASKPRASCWQPGTRTSTSPGV--------------------SEDCLYLN 2285
            E P +W G  +A+    +C  P       P +                    SEDCLYLN
Sbjct: 88   EAPASWPGVRNATTLPPAC--PQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLN 145

Query: 2286 VFIPQNVAP---------------------NASVLVFFHNTMDREESEGWPAIDGSFLAA 2324
            +++P    P                        V++F H     E +      DGS LAA
Sbjct: 146  LYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNM--FDGSVLAA 203

Query: 2325 VGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAA 2384
             GN+IV T +YR+GV GFLS+G     GN+GLLDQ+ AL W+  +I  FGGDP R+++  
Sbjct: 204  YGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFG 263

Query: 2385 DRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM 2444
               GA  + ++LL     +  LF++A+   G+A+S  +V  + +  +    LA +V C  
Sbjct: 264  --SGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV--NYQPLKYTRLLAAKVGCDR 319

Query: 2445 SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY---WGPVIDGHFLREPPARALKRSLW 2501
              S E V CLR+KP+  L D   +      P  Y   +GPV+DG  + + P   +++  +
Sbjct: 320  EDSAEAVECLRRKPSRELVDQDVQ------PARYHIAFGPVVDGDVVPDDPEILMQQGEF 373

Query: 2502 VEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQA---LQNSLGGEDSDARVEA 2558
            +  D+LIG +Q +GL    K V+   ES    S+    +     + N  G  +    +  
Sbjct: 374  LNYDMLIGVNQGEGL----KFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRE 429

Query: 2559 AATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYHAPEN 2616
               + Y+     D+     + L     D+  + P +  A   A       F   YH  + 
Sbjct: 430  TIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQA 489

Query: 2617 YGHGSLELLA---DVQFALGLPFYPA---YEGQFSLEEKSLSLKIMQYFSHFIRSGNPNY 2670
             G       A   ++ +  G+P   A   +   FS  +  LS  +M Y+++F ++G+PN 
Sbjct: 490  EGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ 549

Query: 2671 P 2671
            P
Sbjct: 550  P 550


>gi|33563374 carboxylesterase 3 [Homo sapiens]
          Length = 571

 Score =  185 bits (469), Expect = 6e-46
 Identities = 177/563 (31%), Positives = 245/563 (43%), Gaps = 72/563 (12%)

Query: 2195 EASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTG 2253
            E + P V  +T GR+ GR   ++ GT  + V+ FLG+P+A PPL   RF AP P   W G
Sbjct: 30   EVAQPEVD-TTLGRVRGRQVGVK-GTD-RLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEG 86

Query: 2254 SWDASKPRASCWQPGTRTSTSP----------GVSEDCLYLNVFIPQNVAPNAS--VLVF 2301
              DAS     C Q     ++S            VSEDCL LNV+ P  V   +   V+V+
Sbjct: 87   VRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVW 146

Query: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361
             H       +    + DGS LAA G+++VVT  YR+GV GF S+G     GN G LD VA
Sbjct: 147  VHG--GALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVA 204

Query: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421
            AL WVQ +I  FGGD   V++     G  + S  +L+  A    LF RA+   G   +P 
Sbjct: 205  ALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAG--LFHRAITQSGVITTPG 262

Query: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGP 2481
             + SH     Q I  A  ++C  SS  E+V CL+QK    L     KL     P      
Sbjct: 263  IIDSHPWPLAQKI--ANTLACSSSSPAEMVQCLQQKEGEEL-VLSKKLKNTIYPL----- 314

Query: 2482 VIDGHFLREPPARALKRSLWVEVDLLIGSSQDD--GLINRAKAVKQFEESRGRTSSKTAF 2539
             +DG    + P   LK   +  V  L+G +  +   LI R   +    E   R     A 
Sbjct: 315  TVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSR-EDMLAI 373

Query: 2540 YQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASA 2599
               +  SL     D   E   T       S  D  +  +A +    D FI  P +   S 
Sbjct: 374  STPVLTSL-----DVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSF-SR 427

Query: 2600 WAKRARGNVFMY---HAPENYG----------HGSLELLADVQFALGLPFYPAYEGQFSL 2646
            + + +   VF Y   H P ++           HG     A+  F  G PF      + + 
Sbjct: 428  YLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHG-----AEGAFVFGGPFLMDESSRLAF 482

Query: 2647 -----EEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFS 2701
                 EEK LSL +M  ++HF R+G+PN     S+ +P    PWP F      E Y E +
Sbjct: 483  PEATEEEKQLSLTMMAQWTHFARTGDPN-----SKALP----PWPQF---NQAEQYLEIN 530

Query: 2702 ELLPNRQGLKKADCSFWSKYISS 2724
             +    Q  ++A   FWS+ + S
Sbjct: 531  PVPRAGQKFREAWMQFWSETLPS 553


>gi|7662470 neuroligin 1 [Homo sapiens]
          Length = 823

 Score =  182 bits (462), Expect = 4e-45
 Identities = 155/500 (31%), Positives = 239/500 (47%), Gaps = 74/500 (14%)

Query: 2225 VDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASC----------------WQP 2267
            V QFLGVPYAAPP  ERRFQ PEP + W+   +A++    C                W  
Sbjct: 77   VIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFT 136

Query: 2268 GTRTSTSPGV---SEDCLYLNVFIP-----QNVAPNASVLVFFHNTMDREESEGWPAIDG 2319
                  S  V   SEDCLYLN+++P     ++      V+V+ H     E +      DG
Sbjct: 137  NNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGN--LYDG 194

Query: 2320 SFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRR 2379
            S LA+ GN+IV+T +YR+GV GFLS+G     GN+GLLD + AL W   +I  FGGDP R
Sbjct: 195  SVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLR 254

Query: 2380 VSLAADRGGADVASIHLLTA-------RATNSQ--LFRRAVLMGGSALSPAAVISHERAQ 2430
            +++     GA  + ++LLT        R +NS   LF+RA+   G+ALS  AV S + A 
Sbjct: 255  ITVFG--SGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAV-SFQPA- 310

Query: 2431 QQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY---WGPVIDGHF 2487
            + A  LA +V C +S + E+V CL++KP   L D   +      P  Y   +GPVIDG  
Sbjct: 311  KYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ------PARYHIAFGPVIDGDV 364

Query: 2488 LREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKT---AFYQALQ 2544
            + + P   +++  ++  D+++G +Q +GL    K V+   +S    S+     A    + 
Sbjct: 365  IPDDPQILMEQGEFLNYDIMLGVNQGEGL----KFVENIVDSDDGISASDFDFAVSNFVD 420

Query: 2545 NSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPII---DMASAWA 2601
            N  G  +    +     + Y+      +  +  + L     D+  + P +   D+ S + 
Sbjct: 421  NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 480

Query: 2602 KRARGNVFMYH-------APENYGHGSLELLADVQFALGLPFY---PAYEGQFSLEEKSL 2651
                   F +H       A  +  HG      +V + LG+P       +   FS  +  L
Sbjct: 481  SPTYFYAFYHHCQTDQVPAWADAAHGD-----EVPYVLGIPMIGPTELFPCNFSKNDVML 535

Query: 2652 SLKIMQYFSHFIRSGNPNYP 2671
            S  +M Y+++F ++G+PN P
Sbjct: 536  SAVVMTYWTNFAKTGDPNQP 555


>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
          Length = 607

 Score =  177 bits (448), Expect = 2e-43
 Identities = 151/490 (30%), Positives = 231/490 (47%), Gaps = 63/490 (12%)

Query: 2204 STH-GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPL-NWTGSWDASKPR 2261
            +TH G++LG    + V  +   V  FLG+P+A PPL   RF  PEP  +W+G  D +   
Sbjct: 99   TTHTGQVLG--SLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 156

Query: 2262 ASCWQPGTR-----------TSTSPGVSEDCLYLNVFIP--QNVAPNASVLVFFHNTMDR 2308
            A C Q  T            T  S  +SEDCLYL+++ P   +   N  V+V+ H     
Sbjct: 157  AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGA-- 214

Query: 2309 EESEGWPAI-DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQ 2367
                G  ++ DGS LAA+ N++VV   YR+GV GF S+G    +GNWG LDQVAAL WVQ
Sbjct: 215  -LVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQ 273

Query: 2368 THIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHE 2427
             +I  FGG+P RV++  +  G    S+  L     +  LF  A++  G AL P  + S  
Sbjct: 274  QNIAHFGGNPDRVTIFGESAGG--TSVSSLVVSPISQGLFHGAIMESGVALLPGLIAS-- 329

Query: 2428 RAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHF 2487
             A   +  +A   +C    S+ +V CLR K       ++ ++LA++ PF     V+DG F
Sbjct: 330  SADVISTVVANLSACDQVDSEALVGCLRGK-------SKEEILAINKPFKMIPGVVDGVF 382

Query: 2488 LREPPARALKRSLWVEVDLLIGSSQDD--GLINRAKAVKQFEESRGRTSSKTAFYQALQ- 2544
            L   P   L  + +  V  ++G + ++   LI +   +   ++   R +S+ A  + L  
Sbjct: 383  LPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL 442

Query: 2545 NSLGGEDSDARVEAAATWYYSLEHSTD--DYASFSRALENATRDYFIICPIIDMASAWAK 2602
              L     D   E         E+  D  D  +     +    D   + P + +A     
Sbjct: 443  LMLPPTFGDLLRE---------EYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCS 493

Query: 2603 RARGNVFMY---HAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYF 2659
            RA   V+ Y   H P          L +++     P   A   +F+ EE+ LS K+M+Y+
Sbjct: 494  RA--PVYFYEFQHQP--------SWLKNIR----PPHMKADHVKFTEEEEQLSRKMMKYW 539

Query: 2660 SHFIRSGNPN 2669
            ++F R+GNPN
Sbjct: 540  ANFARNGNPN 549


>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
          Length = 623

 Score =  177 bits (448), Expect = 2e-43
 Identities = 153/494 (30%), Positives = 233/494 (47%), Gaps = 55/494 (11%)

Query: 2204 STH-GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPL-NWTGSWDASKPR 2261
            +TH G++LG    + V  +   V  FLG+P+A PPL   RF  PEP  +W+G  D +   
Sbjct: 99   TTHTGQVLG--SLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 156

Query: 2262 ASCWQPGTR-----------TSTSPGVSEDCLYLNVFIP--QNVAPNASVLVFFHNTMDR 2308
            A C Q  T            T  S  +SEDCLYL+++ P   +   N  V+V+ H     
Sbjct: 157  AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGA-- 214

Query: 2309 EESEGWPAI-DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQ 2367
                G  ++ DGS LAA+ N++VV   YR+GV GF S+G    +GNWG LDQVAAL WVQ
Sbjct: 215  -LVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQ 273

Query: 2368 THIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHE 2427
             +I  FGG+P RV++  +  G    S+  L     +  LF  A++  G AL P  + S  
Sbjct: 274  QNIAHFGGNPDRVTIFGESAGG--TSVSSLVVSPISQGLFHGAIMESGVALLPGLIAS-- 329

Query: 2428 RAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHF 2487
             A   +  +A   +C    S+ +V CLR K       ++ ++LA++ PF     V+DG F
Sbjct: 330  SADVISTVVANLSACDQVDSEALVGCLRGK-------SKEEILAINKPFKMIPGVVDGVF 382

Query: 2488 LREPPARALKRSLWVEVDLLIGSSQDD--GLINRAKAVKQFEESRGRTSSKTAFYQALQ- 2544
            L   P   L  + +  V  ++G + ++   LI +   +   ++   R +S+ A  + L  
Sbjct: 383  LPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL 442

Query: 2545 NSLGGEDSDARVEAAATWYYSLEHSTD--DYASFSRALENATRDYFIICPIIDMASAWAK 2602
              L     D   E         E+  D  D  +     +    D   + P + +A     
Sbjct: 443  LMLPPTFGDLLRE---------EYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCS 493

Query: 2603 RARGNVFMY---HAPENYGH-GSLELLADVQFALGLPFYPAYEG---QFSLEEKSLSLKI 2655
            RA   V+ Y   H P    +     + AD    L   F   + G   +F+ EE+ LS K+
Sbjct: 494  RA--PVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQLSRKM 551

Query: 2656 MQYFSHFIRSGNPN 2669
            M+Y+++F R+GNPN
Sbjct: 552  MKYWANFARNGNPN 565


>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
          Length = 575

 Score =  166 bits (420), Expect = 3e-40
 Identities = 149/532 (28%), Positives = 236/532 (44%), Gaps = 60/532 (11%)

Query: 2225 VDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQPGTRTSTSP-------- 2275
            V+ FLGVP+AAPPL   RF  P+P + W    +A+     C Q                 
Sbjct: 54   VNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYP 113

Query: 2276 --GVSEDCLYLNVFIPQNVAPNAS--VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVV 2331
              GVSEDCLYLN++ P +    +   VLV+F     +  S      DGS LAA  +++VV
Sbjct: 114  KFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS--IFDGSALAAYEDVLVV 171

Query: 2332 TASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADV 2391
               YR+G+FGF ++      GNW   DQVAAL+WVQ +I  FGGDP  V++  +  GA  
Sbjct: 172  VVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAIS 231

Query: 2392 ASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVV 2451
             S  +L+  A    LF +A++  G A+ P          +    +A       S S+ ++
Sbjct: 232  VSSLILSPMAKG--LFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALL 289

Query: 2452 SCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIG-S 2510
             CLR KP+        +LL +S     +  V+DG F    P   L +  +  +  +IG +
Sbjct: 290  RCLRTKPSK-------ELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVN 342

Query: 2511 SQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHST 2570
            + + G +   K   +        S+K+     +QN L        +   A  Y+  +HS 
Sbjct: 343  NHECGFLLPMKEAPEILSG----SNKSLALHLIQNIL--HIPPQYLHLVANEYFHDKHSL 396

Query: 2571 DDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMY---HAPENY-----GHGSL 2622
             +      +L +   D F + P + + + + + A   V+ Y   H P+ +          
Sbjct: 397  TEIRD---SLLDLLGDVFFVVPAL-ITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKA 452

Query: 2623 ELLADVQFALGLPFYPA----YEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKV 2678
            +   +V+F  G  F       +EG  + EEK LS K+M+Y++ F R+GNPN         
Sbjct: 453  DHADEVRFVFGGAFLKGDIVMFEGA-TEEEKLLSRKMMKYWATFARTGNPN--------- 502

Query: 2679 PTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSAD 2730
                + WP +      E Y +    +   Q LK+    FW+  I  + +++D
Sbjct: 503  GNDLSLWPAYNLT---EQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASD 551


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score =  157 bits (398), Expect = 1e-37
 Identities = 157/556 (28%), Positives = 246/556 (44%), Gaps = 82/556 (14%)

Query: 2217 QVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPG 2276
            ++G     VD F G+P+AAP  A    Q P P  W G+  A   +  C Q  T T  S  
Sbjct: 42   KLGLLGDSVDIFKGIPFAAPTKALENPQ-PHP-GWQGTLKAKNFKKRCLQ-ATITQDSTY 98

Query: 2277 VSEDCLYLNVFIPQN---VAPNASVLVFFHNTMDREESEGWPA-------IDGSFLAAVG 2326
              EDCLYLN+++PQ    V+ +  V+++ +       S G  A        DG  +A  G
Sbjct: 99   GDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGS-GHGANFLNNYLYDGEEIATRG 157

Query: 2327 NLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADR 2386
            N+IVVT +YRVG  GFLS+G   + GN+GL DQ  A+ WV+ +I  FGGDP  ++L  + 
Sbjct: 158  NVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGES 217

Query: 2387 GGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSS 2446
             G   AS+ L T    N  L RRA+   G ALSP  +   +     A  +A++V CP+  
Sbjct: 218  AGG--ASVSLQTLSPYNKGLIRRAISQSGVALSPWVI--QKNPLFWAKKVAEKVGCPVGD 273

Query: 2447 SQEVVSCLRQKPANVLNDA-QTKLLAVSGP-FHYWG--PVIDGHFLREPPARALKRSLWV 2502
            +  +  CL+      L  A +  L  +  P  HY G  PVIDG F+   P      +   
Sbjct: 274  AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANA--A 331

Query: 2503 EVDLLIGSSQDDG---------LINRA----------KAVKQFEESRGRTSSKTAFYQAL 2543
            ++D + G++  DG          IN+           K V +F  ++G   +KT F    
Sbjct: 332  DIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTF---- 387

Query: 2544 QNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMAS--AWA 2601
                     D   E+ A    S E+       F       T   F++   I +A   A A
Sbjct: 388  ---------DVYTESWAQ-DPSQENKKKTVVDFE------TDVLFLVPTEIALAQHRANA 431

Query: 2602 KRARGNVFMYHAPENY----GHGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQ 2657
            K A+   +++  P            +   D+Q+  G PF  A    +  +++++S  ++ 
Sbjct: 432  KSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPF--ATPTGYRPQDRTVSKAMIA 489

Query: 2658 YFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPN---RQGLKKAD 2714
            Y+++F ++G+PN        VPT    W  +     G  Y E ++ + +   ++ L+   
Sbjct: 490  YWTNFAKTGDPNMG---DSAVPTH---WEPYTTENSG--YLEITKKMGSSSMKRSLRTNF 541

Query: 2715 CSFWSKYISSLKTSAD 2730
              +W+    +L T  D
Sbjct: 542  LRYWTLTYLALPTVTD 557


>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
          Length = 568

 Score =  155 bits (392), Expect = 5e-37
 Identities = 157/554 (28%), Positives = 241/554 (43%), Gaps = 57/554 (10%)

Query: 2197 SVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSW 2255
            S P V  + HG++LG+  +++     + V  FLG+P+A PPL   RF  P+P   W+   
Sbjct: 22   SSPPVVDTVHGKVLGKFVSLEGFA--QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 79

Query: 2256 DASKPRASCWQPG-----------TRTSTSP-GVSEDCLYLNVFIPQNVAPN--ASVLVF 2301
            +A+     C Q              R    P  +SEDCLYLN++ P ++       V+V+
Sbjct: 80   NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 139

Query: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361
             H       +      DG  LAA  N++VVT  YR+G++GF S+G     GNWG LDQVA
Sbjct: 140  IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 197

Query: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421
            AL WVQ +I  FGG+P  V++  +  G +  S+ +L+  A N  LF RA+   G AL+ +
Sbjct: 198  ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN--LFHRAISESGVALT-S 254

Query: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH---- 2477
             ++     +  A  +A    C  ++S  +V CLRQK    L +   K+  +S        
Sbjct: 255  VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 314

Query: 2478 ----YWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRT 2533
                  G VIDG  L + P        +  V  ++G ++ +        +  +  S G+ 
Sbjct: 315  ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 374

Query: 2534 SSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPI 2593
              KTA    L  S         +   AT  Y     TDD         +   D     P 
Sbjct: 375  DQKTAM-SLLWKSYPLVCIAKELIPEATEKYL--GGTDDTVKKKDLFLDLIADVMFGVPS 431

Query: 2594 IDMASAWAKRARGNVFMYHAPENYGHGS-------LELLADVQFAL-GLPFYPAYEGQFS 2645
            + +A    + A    +MY         S       +    D  F++ G PF    EG  S
Sbjct: 432  VIVARN-HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK--EGA-S 487

Query: 2646 LEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLP 2705
             EE  LS  +M+++++F R+GNPN        +P     WP++  +   E Y +      
Sbjct: 488  EEEIRLSKMVMKFWANFARNGNPN-----GEGLP----HWPEYNQK---EGYLQIGANTQ 535

Query: 2706 NRQGLKKADCSFWS 2719
              Q LK  + +FW+
Sbjct: 536  AAQKLKDKEVAFWT 549


>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
          Length = 567

 Score =  155 bits (392), Expect = 5e-37
 Identities = 157/554 (28%), Positives = 241/554 (43%), Gaps = 57/554 (10%)

Query: 2197 SVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSW 2255
            S P V  + HG++LG+  +++     + V  FLG+P+A PPL   RF  P+P   W+   
Sbjct: 21   SSPPVVDTVHGKVLGKFVSLEGFA--QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 78

Query: 2256 DASKPRASCWQPG-----------TRTSTSP-GVSEDCLYLNVFIPQNVAPN--ASVLVF 2301
            +A+     C Q              R    P  +SEDCLYLN++ P ++       V+V+
Sbjct: 79   NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 138

Query: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361
             H       +      DG  LAA  N++VVT  YR+G++GF S+G     GNWG LDQVA
Sbjct: 139  IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196

Query: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421
            AL WVQ +I  FGG+P  V++  +  G +  S+ +L+  A N  LF RA+   G AL+ +
Sbjct: 197  ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN--LFHRAISESGVALT-S 253

Query: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH---- 2477
             ++     +  A  +A    C  ++S  +V CLRQK    L +   K+  +S        
Sbjct: 254  VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313

Query: 2478 ----YWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRT 2533
                  G VIDG  L + P        +  V  ++G ++ +        +  +  S G+ 
Sbjct: 314  ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373

Query: 2534 SSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPI 2593
              KTA    L  S         +   AT  Y     TDD         +   D     P 
Sbjct: 374  DQKTAM-SLLWKSYPLVCIAKELIPEATEKYL--GGTDDTVKKKDLFLDLIADVMFGVPS 430

Query: 2594 IDMASAWAKRARGNVFMYHAPENYGHGS-------LELLADVQFAL-GLPFYPAYEGQFS 2645
            + +A    + A    +MY         S       +    D  F++ G PF    EG  S
Sbjct: 431  VIVARN-HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK--EGA-S 486

Query: 2646 LEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLP 2705
             EE  LS  +M+++++F R+GNPN        +P     WP++  +   E Y +      
Sbjct: 487  EEEIRLSKMVMKFWANFARNGNPN-----GEGLP----HWPEYNQK---EGYLQIGANTQ 534

Query: 2706 NRQGLKKADCSFWS 2719
              Q LK  + +FW+
Sbjct: 535  AAQKLKDKEVAFWT 548


>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
          Length = 566

 Score =  155 bits (392), Expect = 5e-37
 Identities = 159/555 (28%), Positives = 243/555 (43%), Gaps = 60/555 (10%)

Query: 2197 SVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSW 2255
            S P V  + HG++LG+  +++     + V  FLG+P+A PPL   RF  P+P   W+   
Sbjct: 21   SSPPVVDTVHGKVLGKFVSLEGFA--QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 78

Query: 2256 DASKPRASCWQPG-----------TRTSTSP-GVSEDCLYLNVFIPQNVAPN--ASVLVF 2301
            +A+     C Q              R    P  +SEDCLYLN++ P ++       V+V+
Sbjct: 79   NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 138

Query: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361
             H       +      DG  LAA  N++VVT  YR+G++GF S+G     GNWG LDQVA
Sbjct: 139  IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196

Query: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421
            AL WVQ +I  FGG+P  V++  +  G +  S+ +L+  A N  LF RA+   G AL+ +
Sbjct: 197  ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN--LFHRAISESGVALT-S 253

Query: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH---- 2477
             ++     +  A  +A    C  ++S  +V CLRQK    L +   K+  +S        
Sbjct: 254  VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313

Query: 2478 ----YWGPVIDGHFLREPPARALKRSLWVEVDLLIG-SSQDDGLINRAKAVKQFEESRGR 2532
                  G VIDG  L + P        +  V  ++G + Q+ G +     +  +  S G+
Sbjct: 314  ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWL--IPMLMSYPLSEGQ 371

Query: 2533 TSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICP 2592
               KTA    L  S         +   AT  Y     TDD         +   D     P
Sbjct: 372  LDQKTAM-SLLWKSYPLVCIAKELIPEATEKYL--GGTDDTVKKKDLFLDLIADVMFGVP 428

Query: 2593 IIDMASAWAKRARGNVFMYHAPENYGHGS-------LELLADVQFAL-GLPFYPAYEGQF 2644
             + +A    + A    +MY         S       +    D  F++ G PF    EG  
Sbjct: 429  SVIVARN-HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK--EGA- 484

Query: 2645 SLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELL 2704
            S EE  LS  +M+++++F R+GNPN        +P     WP++  +   E Y +     
Sbjct: 485  SEEEIRLSKMVMKFWANFARNGNPN-----GEGLP----HWPEYNQK---EGYLQIGANT 532

Query: 2705 PNRQGLKKADCSFWS 2719
               Q LK  + +FW+
Sbjct: 533  QAAQKLKDKEVAFWT 547


>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
          Length = 525

 Score =  154 bits (389), Expect = 1e-36
 Identities = 143/520 (27%), Positives = 219/520 (42%), Gaps = 86/520 (16%)

Query: 2225 VDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQPGTRTSTSP-------- 2275
            V+ FLGVP+AAPPL   RF  P+P + W    +A+     C Q                 
Sbjct: 54   VNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYP 113

Query: 2276 --GVSEDCLYLNVFIPQNVAPNAS--VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVV 2331
              GVSEDCLYLN++ P +    +   VLV+F     +  S      DGS LAA  +++VV
Sbjct: 114  KFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS--IFDGSALAAYEDVLVV 171

Query: 2332 TASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADV 2391
               YR+G+FGF ++      GNW   DQVAAL+WVQ +I  FGGDP  V++  +  GA  
Sbjct: 172  VVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAIS 231

Query: 2392 ASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVV 2451
             S  +L+  A    LF +A++  G A+ P          +    +A       S S+ ++
Sbjct: 232  VSSLILSPMAKG--LFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALL 289

Query: 2452 SCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIG-S 2510
             CLR KP+        +LL +S     +  V+DG F    P   L +  +  +  +IG +
Sbjct: 290  RCLRTKPSK-------ELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVN 342

Query: 2511 SQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHST 2570
            + + G +   K   +        S+K+     +QN L        +   A  Y+  +HS 
Sbjct: 343  NHECGFLLPMKEAPEILSG----SNKSLALHLIQNIL--HIPPQYLHLVANEYFHDKHSL 396

Query: 2571 DDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQF 2630
             +      +L +   D F + P +  A             YH       G+ E       
Sbjct: 397  TEIRD---SLLDLLGDVFFVVPALITA------------RYHR-----EGATE------- 429

Query: 2631 ALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVP 2690
                            EEK LS K+M+Y++ F R+GNPN             + WP +  
Sbjct: 430  ----------------EEKLLSRKMMKYWATFARTGNPN---------GNDLSLWPAYNL 464

Query: 2691 RAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSAD 2730
                E Y +    +   Q LK+    FW+  I  + +++D
Sbjct: 465  T---EQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASD 501


>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
          Length = 491

 Score =  138 bits (347), Expect = 9e-32
 Identities = 112/329 (34%), Positives = 155/329 (47%), Gaps = 32/329 (9%)

Query: 2203 ISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPR 2261
            ++ +G L G+   + VG +  QV  FLGVP++ PPL   RF  PEP   W G  DA+   
Sbjct: 30   VTKYGTLQGKQ--MHVGKTPIQV--FLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYP 85

Query: 2262 ASCWQPGTRTSTSPGVS-----------EDCLYLNVFIPQNVA--PNASVLVFFHNTMDR 2308
              C Q       S  VS           EDCLYLNV+ P      P   V+V+F      
Sbjct: 86   PGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFI 145

Query: 2309 EESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQT 2368
              +    + +GS LAA   +++V   +R+G+FGFLS+      GNWGLLDQ+AAL WVQ 
Sbjct: 146  VGAAS--SYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQE 203

Query: 2369 HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHER 2428
            +I  FGGDP  V+L     GA   SI  L      S LF RA+   G+AL    + S+  
Sbjct: 204  NIAAFGGDPGNVTLFGQSAGA--MSISGLMMSPLASGLFHRAISQSGTALFRLFITSN-- 259

Query: 2429 AQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH------YW--G 2480
              + A  +A    C  +S+Q +V+CLR      +     K+  +   F        W   
Sbjct: 260  PLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMS 319

Query: 2481 PVIDGHFLREPPARALKRSLWVEVDLLIG 2509
            PV+DG  + + P   L +     V  L+G
Sbjct: 320  PVVDGVVIPDDPLVLLTQGKVSSVPYLLG 348



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 1/49 (2%)

Query: 2622 LELLADVQFALGLPFYPAYEGQFSL-EEKSLSLKIMQYFSHFIRSGNPN 2669
            ++++ D  F         Y    S+ +EK+LSL++M+Y+++F R+GNPN
Sbjct: 391  MDIVQDATFVYATLQTAHYHRGLSMGKEKALSLQMMKYWANFARTGNPN 439


>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
          Length = 327

 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 62/192 (32%), Positives = 93/192 (48%), Gaps = 9/192 (4%)

Query: 2318 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 2377
            DGS LAA  +++VV   YR+G+FGF ++      GNW   DQVAAL+WVQ +I  FGGDP
Sbjct: 32   DGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDP 91

Query: 2378 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALA 2437
              V++  +  GA   S  +L+  A    LF +AV+  G A+            +    +A
Sbjct: 92   SSVTIFGESVGAISVSSLMLSPMAEG--LFHKAVMESGVAIILYLKAHDYEKSEDLQVVA 149

Query: 2438 KEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALK 2497
            +      S S+  + CLR K       +  +LL +S     +  V+DG F    P   L 
Sbjct: 150  QFCGYNASDSEAPLRCLRTK-------SSKELLTLSQKTKAFTQVVDGAFFPNEPLDLLS 202

Query: 2498 RSLWVEVDLLIG 2509
            +  +  +  +IG
Sbjct: 203  QKAFKAIPSIIG 214


>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
          Length = 327

 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 62/192 (32%), Positives = 93/192 (48%), Gaps = 9/192 (4%)

Query: 2318 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 2377
            DGS LAA  +++VV   YR+G+FGF ++      GNW   DQVAAL+WVQ +I  FGGDP
Sbjct: 32   DGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDP 91

Query: 2378 RRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALA 2437
              V++  +  GA   S  +L+  A    LF +AV+  G A+            +    +A
Sbjct: 92   SSVTIFGESVGAISVSSLILSPMAEG--LFHKAVMESGVAIILYLKAHDYEKSEDLQVVA 149

Query: 2438 KEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALK 2497
            +      S S+  + CLR K       +  +LL +S     +  V+DG F    P   L 
Sbjct: 150  QFCGYNASDSEAPLRCLRTK-------SSKELLTLSQKTKAFTQVVDGAFFPNEPLDLLS 202

Query: 2498 RSLWVEVDLLIG 2509
            +  +  +  +IG
Sbjct: 203  QKAFKAIPSIIG 214


>gi|144953895 nidogen 2 precursor [Homo sapiens]
          Length = 1375

 Score = 89.4 bits (220), Expect = 5e-17
 Identities = 52/148 (35%), Positives = 71/148 (47%), Gaps = 18/148 (12%)

Query: 31   LRPCELQRETAFLKQAD-----YVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQ 85
            L PCE Q+  A  + A      ++PQC E G+F  +QC      CWCV  +G EV G++ 
Sbjct: 937  LTPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQT 996

Query: 86   P--GRPVAC----------LSFCQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDV 133
            P    P  C           + C+  ++ +L        D  Y+PQC D G + P+QC  
Sbjct: 997  PPGSTPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHG 1056

Query: 134  QQVQCWCVDAEGMEVYGTR-QLGRPKRC 160
            +   CWCVD +G EV GTR Q G    C
Sbjct: 1057 KSDFCWCVDKDGREVQGTRSQPGTTPAC 1084



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 45/129 (34%), Positives = 64/129 (49%), Gaps = 17/129 (13%)

Query: 614  RLFVPSCTTEGSYEDVQCF--SGECWCVNSWGKELPGSRVRGGQ--PRC----------P 659
            R  +P C  +G++  +QC   +G CWCV+  G E+PG++   G   P C          P
Sbjct: 957  RFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPP 1016

Query: 660  TDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE--CYCVDAEGQAIPGTR 717
            T CE+ R  +    G  P     +VP C   GHF+P+QC      C+CVD +G+ + GTR
Sbjct: 1017 TICERWRENLLEHYGGTPRDDQ-YVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTR 1075

Query: 718  SAIGKPKKC 726
            S  G    C
Sbjct: 1076 SQPGTTPAC 1084



 Score = 75.1 bits (183), Expect = 9e-13
 Identities = 42/126 (33%), Positives = 62/126 (49%), Gaps = 6/126 (4%)

Query: 1027 YMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQC-PTTCEKSRTSGL 1085
            ++PQCD  G++ P+QCH  TG CWCVD  G  +PG+ T      P C P+     R   +
Sbjct: 959  HIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTI 1018

Query: 1086 LSSWKQARSQE-NPSPK-DLFVPACLETGEYARLQASGAG--TWCVDPASGEELRPGSSS 1141
               W++   +    +P+ D +VP C + G +  LQ  G     WCVD   G E++   S 
Sbjct: 1019 CERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVD-KDGREVQGTRSQ 1077

Query: 1142 SAQCPS 1147
                P+
Sbjct: 1078 PGTTPA 1083



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 42/122 (34%), Positives = 62/122 (50%), Gaps = 8/122 (6%)

Query: 660  TDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE--CYCVDAEGQAIPGTR 717
            T CE+Q+   Q+       G+   +P C  +G+FLP+QC  S   C+CVD +G  +PGT+
Sbjct: 938  TPCEQQQRHAQAQYAYP--GARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQ 995

Query: 718  SAIGK-PKKC-PTPCQLQSEQAFL-RTVQALLSNSSMLPTLSDTYIPQCSTDGQWRQVQC 774
            +  G  P  C P+P   Q       R  + LL +    P   D Y+PQC   G +  +QC
Sbjct: 996  TPPGSTPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPR-DDQYVPQCDDLGHFIPLQC 1054

Query: 775  NG 776
            +G
Sbjct: 1055 HG 1056



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 49/167 (29%), Positives = 70/167 (41%), Gaps = 18/167 (10%)

Query: 45   QADYVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQIL 104
            Q   V +C+E+       C N   S  C    G    G +      + L+ C+ Q+Q+  
Sbjct: 889  QCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCE-QQQRHA 947

Query: 105  LSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQL--GRPKRC-- 160
             + Y       ++PQC + G++ P+QC      CWCVD +G EV GT+      P  C  
Sbjct: 948  QAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGP 1007

Query: 161  --------PRSCEIRNRRLLHGVG-----DKSPPQCSAEGEFMPVQC 194
                    P  CE     LL   G     D+  PQC   G F+P+QC
Sbjct: 1008 SPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQC 1054



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 42/126 (33%), Positives = 55/126 (43%), Gaps = 21/126 (16%)

Query: 1105 VPACLETGEYARLQASGAG--TWCVDP----ASGEELRPGSSS---------SAQCPSLC 1149
            +P C E G +  LQ  G+    WCVDP      G +  PGS+          + + P++C
Sbjct: 960  IPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTIC 1019

Query: 1150 NVLKSGVLSRRVSPG----YVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTR-VT 1204
               +  +L           YVP C  + G F P+QC      CWCV   G EV GTR   
Sbjct: 1020 ERWRENLLEHYGGTPRDDQYVPQCD-DLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQP 1078

Query: 1205 GGQPAC 1210
            G  PAC
Sbjct: 1079 GTTPAC 1084



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 8/71 (11%)

Query: 296  RCPTKCE------VERFTATSFGHPYVPSCRRNGDYQAVQCQTEGP-CWCVDAQGKEMHG 348
            R PT CE      +E +  T     YVP C   G +  +QC  +   CWCVD  G+E+ G
Sbjct: 1014 RPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQG 1073

Query: 349  TRQQ-GEPPSC 358
            TR Q G  P+C
Sbjct: 1074 TRSQPGTTPAC 1084



 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 18/40 (45%), Positives = 25/40 (62%)

Query: 1023 RSGPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGS 1062
            R   Y+PQCD  G + P+QCH  +  CWCVD+ G  + G+
Sbjct: 1035 RDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGT 1074



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 1132 GEELRPGSSSSAQCPSLCNVLKSGVLSRRVSPG---YVPACRAEDGGFSPVQCDQAQGSC 1188
            G +  P S+SS    + C   +    ++   PG   ++P C  E G F P+QC  + G C
Sbjct: 926  GFQCIPDSTSSL---TPCEQQQRHAQAQYAYPGARFHIPQCD-EQGNFLPLQCHGSTGFC 981

Query: 1189 WCVMDSGEEVPGTRVTGGQPACESPRC 1215
            WCV   G EVPGT+     P    P C
Sbjct: 982  WCVDPDGHEVPGTQT---PPGSTPPHC 1005



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 8/68 (11%)

Query: 299  TKCEVE-RFTATSFGHP----YVPSCRRNGDYQAVQCQ-TEGPCWCVDAQGKEMHGTRQQ 352
            T CE + R     + +P    ++P C   G++  +QC  + G CWCVD  G E+ GT+  
Sbjct: 938  TPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTP 997

Query: 353  --GEPPSC 358
                PP C
Sbjct: 998  PGSTPPHC 1005



 Score = 39.3 bits (90), Expect = 0.055
 Identities = 13/24 (54%), Positives = 18/24 (75%)

Query: 898  CWCVDEAGQELEGMRSEPSKLPTC 921
            CWCVD+ G+E++G RS+P   P C
Sbjct: 1061 CWCVDKDGREVQGTRSQPGTTPAC 1084


>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
          Length = 457

 Score = 78.6 bits (192), Expect = 8e-14
 Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 20/211 (9%)

Query: 1027 YMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTC-------EK 1079
            ++P+C+  G++  VQCH+ TG+CWCV   G  I G  TA + + P+CP +        E 
Sbjct: 109  FIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISG--TAVAHKTPRCPGSVNEKLPQREG 166

Query: 1080 SRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQ--ASGAGTWCVDPASGEELRP 1137
            +  +  L  +    S +  +P        LET      +  AS   T   +     + + 
Sbjct: 167  TGKTVSLQIFSVLNSDDAAAP-------ALETQPQGDEEDIASRYPTLWTEQVKSRQNKT 219

Query: 1138 GSSSSAQCPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCVM-DSGE 1196
              +S + C              +     +P C A  G + PVQC  + G CWCV+ D+G 
Sbjct: 220  NKNSVSSCDQEHQSALEEAKQPKNDNVVIPEC-AHGGLYKPVQCHPSTGYCWCVLVDTGR 278

Query: 1197 EVPGTRVTGGQPACESPRCPLPFNASEVVGG 1227
             +PGT     QP C++     P  A ++  G
Sbjct: 279  PIPGTSTRYEQPKCDNTARAHPAKARDLYKG 309



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 598 VMETVLSSQTCEQTPERLFVPSCTTEGSYEDVQC--FSGECWCVNSWGKELPGSRVRGGQ 655
           V E   + +   +  +++F+P C  +G+Y  VQC  ++G CWCV   G+ + G+ V    
Sbjct: 91  VAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKT 150

Query: 656 PRCP 659
           PRCP
Sbjct: 151 PRCP 154



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 8/114 (7%)

Query: 50  PQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGYI 109
           P CA DG     +C+     C       +     +   R VA   + Q Q ++       
Sbjct: 51  PLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKDVSRCVAERKYTQEQARK------- 103

Query: 110 NSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS 163
                 ++P+C D G Y+ VQC      CWCV   G  + GT    +  RCP S
Sbjct: 104 -EFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGS 156



 Score = 45.4 bits (106), Expect = 8e-04
 Identities = 40/167 (23%), Positives = 65/167 (38%), Gaps = 27/167 (16%)

Query: 45  QADYVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQ-- 102
           Q  ++P+C +DG++  VQC +    CWCV  NG  + G+    +   C      +  Q  
Sbjct: 106 QQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSVNEKLPQRE 165

Query: 103 -------ILLSGYINSTDTSY-LPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQL 154
                  + +   +NS D +    + Q  GD   +    +    W       E   +RQ 
Sbjct: 166 GTGKTVSLQIFSVLNSDDAAAPALETQPQGDEEDIAS--RYPTLW------TEQVKSRQN 217

Query: 155 GRPKRCPRSCEIRNRRLLHGVGDKSP-------PQCSAEGEFMPVQC 194
              K    SC+  ++  L     K P       P+C+  G + PVQC
Sbjct: 218 KTNKNSVSSCDQEHQSALEEA--KQPKNDNVVIPECAHGGLYKPVQC 262



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 613 ERLFVPSCTTEGSYEDVQCF--SGECWCV-NSWGKELPGSRVRGGQPRCPTDCEKQRARM 669
           + + +P C   G Y+ VQC   +G CWCV    G+ +PG+  R  QP+C        A+ 
Sbjct: 244 DNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKA 303

Query: 670 QSL 672
           + L
Sbjct: 304 RDL 306



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 311 FGHPYVPSCRRNGDYQAVQCQT-EGPCWCVDAQGKEMHGTRQQGEPPSC 358
           F   ++P C  +G Y  VQC +  G CWCV   G+ + GT    + P C
Sbjct: 105 FQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRC 153



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 1/84 (1%)

Query: 78  SEVLGSRQPGRPVACLSFCQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQ 137
           +E + SRQ       +S C  + Q  L        D   +P+C   G Y PVQC      
Sbjct: 209 TEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGY 268

Query: 138 CWCVDAE-GMEVYGTRQLGRPKRC 160
           CWCV  + G  + GT       +C
Sbjct: 269 CWCVLVDTGRPIPGTSTRYEQPKC 292



 Score = 38.9 bits (89), Expect = 0.071
 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)

Query: 676 QPAGSTLFVPACTSEGHFLPVQCFNSE--CYCVDAE-GQAIPGTRSAIGKPK 724
           QP    + +P C   G + PVQC  S   C+CV  + G+ IPGT +   +PK
Sbjct: 240 QPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPK 291



 Score = 38.1 bits (87), Expect = 0.12
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%)

Query: 682 LFVPACTSEGHFLPVQC--FNSECYCVDAEGQAIPGTRSAIGKPKKCP 727
           +F+P C  +G +  VQC  +   C+CV   G+ I GT  A  K  +CP
Sbjct: 108 VFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVA-HKTPRCP 154



 Score = 33.1 bits (74), Expect = 3.9
 Identities = 11/25 (44%), Positives = 15/25 (60%)

Query: 49  VPQCAEDGSFQTVQCQNDGRSCWCV 73
           +P+CA  G ++ VQC      CWCV
Sbjct: 248 IPECAHGGLYKPVQCHPSTGYCWCV 272


>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
            [Homo sapiens]
          Length = 435

 Score = 75.1 bits (183), Expect = 9e-13
 Identities = 54/192 (28%), Positives = 81/192 (42%), Gaps = 17/192 (8%)

Query: 1027 YMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKSRTSGLL 1086
            ++P+C   GS+  VQCH  TG+CWCV   G  I GS       +      C  S T   L
Sbjct: 114  FVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPV------CSGSVTDKPL 167

Query: 1087 SSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSS--SSAQ 1144
            S     R  +   P        +  G+    + +    W       +     ++  +S +
Sbjct: 168  SQGNSGRKDDGSKPTPTMETQPVFDGD----EITAPTLWIKHLVIKDSKLNNTNIRNSEK 223

Query: 1145 CPSLCNVLKSGVLSRRVSPG---YVPACRAEDGGFSPVQCDQAQGSCWCVM-DSGEEVPG 1200
              S     +S +   + +P     +P C A  G + PVQC Q+ G CWCV+ D+G  +PG
Sbjct: 224  VYSCDQERQSALEEAQQNPREGIVIPEC-APGGLYKPVQCHQSTGYCWCVLVDTGRPLPG 282

Query: 1201 TRVTGGQPACES 1212
            T      P+CES
Sbjct: 283  TSTRYVMPSCES 294



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 62/234 (26%), Positives = 89/234 (38%), Gaps = 39/234 (16%)

Query: 881  GSYSDFSTPLAHFDLRNCWCVDEAGQELEGMRSEPSKLPTCPGSCEEAKLRVLQFIRETE 940
            G    F+    H     CWCV   G+ + G  S  +K P C GS  +  L      R+ +
Sbjct: 119  GEDGSFTQVQCHTYTGYCWCVTPDGKPISGS-SVQNKTPVCSGSVTDKPLSQGNSGRKDD 177

Query: 941  EIVSASNSSRFPLGESFLVAKGIRLRNEDLGLPPLFPPREAFAEQFLRGSD--YAIRLAA 998
                   S   P  E+  V  G  +    L +  L           +R S+  Y+     
Sbjct: 178  ------GSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQER 231

Query: 999  QSTLSFYQRRRFSPDDSAGASALLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCV-DEKGG 1057
            QS L   Q+               R G  +P+C   G ++PVQCH  TG+CWCV  + G 
Sbjct: 232  QSALEEAQQNP-------------REGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGR 278

Query: 1058 FIPGSLTARSLQIPQCPTTCEKSRTSGLLSSWKQARSQENPSP-KDLFVPACLE 1110
             +PG  T+    +P C              S  +A++ E   P KD  +P C E
Sbjct: 279  PLPG--TSTRYVMPSC-------------ESDARAKTTEADDPFKDRELPGCPE 317



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 1106 PACLETGEYARLQASGAGTWCVDPASGEELRPGSSSSAQCPSLCNVLKSGVLSRRVSPG- 1164
            P C   G             C DP  G   R     + Q  S C + ++  L +   P  
Sbjct: 54   PICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQ--SKCRLERAQALEQAKKPQE 111

Query: 1165 --YVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPAC 1210
              +VP C  EDG F+ VQC    G CWCV   G+ + G+ V    P C
Sbjct: 112  AVFVPEC-GEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVC 158



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

Query: 599 METVLSSQTCEQTPERLFVPSCTTEGSYEDVQC--FSGECWCVNSWGKELPGSRVRGGQP 656
           +E   + +  ++  E +FVP C  +GS+  VQC  ++G CWCV   GK + GS V+   P
Sbjct: 97  LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156

Query: 657 RC 658
            C
Sbjct: 157 VC 158



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 5/64 (7%)

Query: 34  CELQRETAFLK-----QADYVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGR 88
           C L+R  A  +     +A +VP+C EDGSF  VQC      CWCV  +G  + GS    +
Sbjct: 95  CRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK 154

Query: 89  PVAC 92
              C
Sbjct: 155 TPVC 158



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 299 TKCEVERFTATSFGHP-----YVPSCRRNGDYQAVQCQT-EGPCWCVDAQGKEMHGTRQQ 352
           +KC +ER  A           +VP C  +G +  VQC T  G CWCV   GK + G+  Q
Sbjct: 93  SKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ 152

Query: 353 GEPPSCA 359
            + P C+
Sbjct: 153 NKTPVCS 159



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 8/115 (6%)

Query: 50  PQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGR-PVACLSFCQLQKQQILLSGY 108
           P CA DG      C+     C          LG    GR   A  S C+L++ Q L    
Sbjct: 54  PICASDGRSYESMCEYQRAKC------RDPTLGVVHRGRCKDAGQSKCRLERAQALEQAK 107

Query: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS 163
               +  ++P+C + G +  VQC      CWCV  +G  + G+    +   C  S
Sbjct: 108 -KPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGS 161



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%)

Query: 606 QTCEQTP-ERLFVPSCTTEGSYEDVQCF--SGECWCV-NSWGKELPGSRVRGGQPRCPTD 661
           +  +Q P E + +P C   G Y+ VQC   +G CWCV    G+ LPG+  R   P C +D
Sbjct: 236 EEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD 295



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 12/112 (10%)

Query: 608 CEQTPERLFVPSCTTEGSYEDVQCFSGECWCVN-SWGKELPGSRVRGGQPRCPTDCEKQR 666
           C +T  +   P C ++G   +  C      C + + G    G     GQ +C  +     
Sbjct: 47  CSRTQPK---PICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLE----- 98

Query: 667 ARMQSLMGSQPAGSTLFVPACTSEGHFLPVQC--FNSECYCVDAEGQAIPGT 716
            R Q+L  ++     +FVP C  +G F  VQC  +   C+CV  +G+ I G+
Sbjct: 99  -RAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGS 149



 Score = 41.2 bits (95), Expect = 0.014
 Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 96  CQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAE-GMEVYGTRQL 154
           C  ++Q  L     N  +   +P+C   G Y PVQC      CWCV  + G  + GT   
Sbjct: 227 CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTR 286

Query: 155 GRPKRCPRSCEIRNRRLLHGVGDKSPPQCSAEGEFMPVQCKFVN--TTDMM 203
                C      +         D+  P C  EG+ M      ++  TTDM+
Sbjct: 287 YVMPSCESDARAKTTEADDPFKDRELPGC-PEGKKMEFITSLLDALTTDMV 336



 Score = 40.8 bits (94), Expect = 0.019
 Identities = 67/276 (24%), Positives = 102/276 (36%), Gaps = 54/276 (19%)

Query: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS-CEIR 167
           ++ + T   P C   G      C+ Q+ +C           G    GR K   +S C + 
Sbjct: 45  LHCSRTQPKPICASDGRSYESMCEYQRAKC------RDPTLGVVHRGRCKDAGQSKCRLE 98

Query: 168 NRRLLHGVGDKSP------PQCSAEGEFMPVQCKFVNTTDMMIFDLVHSYNRF-----PD 216
             + L     K P      P+C  +G F  VQC              H+Y  +     PD
Sbjct: 99  RAQALEQA--KKPQEAVFVPECGEDGSFTQVQC--------------HTYTGYCWCVTPD 142

Query: 217 AF-VTFSSFQRRFPEVSGYCHCAD-SQGRE-LAETGLELLLDEIYDTIFAGLDLPSTFTE 273
              ++ SS Q + P  SG       SQG     + G +         +F G ++    T 
Sbjct: 143 GKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEI----TA 198

Query: 274 TTLYRILQRRFLAVQSVISGRFRCPTK---CEVERFTATSFGHP------YVPSCRRNGD 324
            TL+  ++   +    + +   R   K   C+ ER +A             +P C   G 
Sbjct: 199 PTLW--IKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGL 256

Query: 325 YQAVQC-QTEGPCWCVDAQ-GKEMHGTRQQGEPPSC 358
           Y+ VQC Q+ G CWCV    G+ + GT  +   PSC
Sbjct: 257 YKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSC 292



 Score = 35.8 bits (81), Expect = 0.60
 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 645 ELPGSRVRGGQPRCPTDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE-- 702
           +L  + +R  +     D E+Q A  ++    Q     + +P C   G + PVQC  S   
Sbjct: 212 KLNNTNIRNSEKVYSCDQERQSALEEA---QQNPREGIVIPECAPGGLYKPVQCHQSTGY 268

Query: 703 CYCVDAE-GQAIPGTRSAIGKPKKCPTPCQLQSEQA 737
           C+CV  + G+ +PGT +    P  C +  + ++ +A
Sbjct: 269 CWCVLVDTGRPLPGTSTRYVMP-SCESDARAKTTEA 303



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 14/53 (26%), Positives = 28/53 (52%), Gaps = 6/53 (11%)

Query: 27  DAQPLRPCELQRETAFL------KQADYVPQCAEDGSFQTVQCQNDGRSCWCV 73
           +++ +  C+ +R++A        ++   +P+CA  G ++ VQC      CWCV
Sbjct: 220 NSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCV 272


>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
            [Homo sapiens]
          Length = 434

 Score = 75.1 bits (183), Expect = 9e-13
 Identities = 54/192 (28%), Positives = 81/192 (42%), Gaps = 17/192 (8%)

Query: 1027 YMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKSRTSGLL 1086
            ++P+C   GS+  VQCH  TG+CWCV   G  I GS       +      C  S T   L
Sbjct: 114  FVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPV------CSGSVTDKPL 167

Query: 1087 SSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSS--SSAQ 1144
            S     R  +   P        +  G+    + +    W       +     ++  +S +
Sbjct: 168  SQGNSGRKDDGSKPTPTMETQPVFDGD----EITAPTLWIKHLVIKDSKLNNTNIRNSEK 223

Query: 1145 CPSLCNVLKSGVLSRRVSPG---YVPACRAEDGGFSPVQCDQAQGSCWCVM-DSGEEVPG 1200
              S     +S +   + +P     +P C A  G + PVQC Q+ G CWCV+ D+G  +PG
Sbjct: 224  VYSCDQERQSALEEAQQNPREGIVIPEC-APGGLYKPVQCHQSTGYCWCVLVDTGRPLPG 282

Query: 1201 TRVTGGQPACES 1212
            T      P+CES
Sbjct: 283  TSTRYVMPSCES 294



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 62/234 (26%), Positives = 89/234 (38%), Gaps = 39/234 (16%)

Query: 881  GSYSDFSTPLAHFDLRNCWCVDEAGQELEGMRSEPSKLPTCPGSCEEAKLRVLQFIRETE 940
            G    F+    H     CWCV   G+ + G  S  +K P C GS  +  L      R+ +
Sbjct: 119  GEDGSFTQVQCHTYTGYCWCVTPDGKPISGS-SVQNKTPVCSGSVTDKPLSQGNSGRKDD 177

Query: 941  EIVSASNSSRFPLGESFLVAKGIRLRNEDLGLPPLFPPREAFAEQFLRGSD--YAIRLAA 998
                   S   P  E+  V  G  +    L +  L           +R S+  Y+     
Sbjct: 178  ------GSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQER 231

Query: 999  QSTLSFYQRRRFSPDDSAGASALLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCV-DEKGG 1057
            QS L   Q+               R G  +P+C   G ++PVQCH  TG+CWCV  + G 
Sbjct: 232  QSALEEAQQNP-------------REGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGR 278

Query: 1058 FIPGSLTARSLQIPQCPTTCEKSRTSGLLSSWKQARSQENPSP-KDLFVPACLE 1110
             +PG  T+    +P C              S  +A++ E   P KD  +P C E
Sbjct: 279  PLPG--TSTRYVMPSC-------------ESDARAKTTEADDPFKDRELPGCPE 317



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 1106 PACLETGEYARLQASGAGTWCVDPASGEELRPGSSSSAQCPSLCNVLKSGVLSRRVSPG- 1164
            P C   G             C DP  G   R     + Q  S C + ++  L +   P  
Sbjct: 54   PICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQ--SKCRLERAQALEQAKKPQE 111

Query: 1165 --YVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPAC 1210
              +VP C  EDG F+ VQC    G CWCV   G+ + G+ V    P C
Sbjct: 112  AVFVPEC-GEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVC 158



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

Query: 599 METVLSSQTCEQTPERLFVPSCTTEGSYEDVQC--FSGECWCVNSWGKELPGSRVRGGQP 656
           +E   + +  ++  E +FVP C  +GS+  VQC  ++G CWCV   GK + GS V+   P
Sbjct: 97  LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156

Query: 657 RC 658
            C
Sbjct: 157 VC 158



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 5/64 (7%)

Query: 34  CELQRETAFLK-----QADYVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGR 88
           C L+R  A  +     +A +VP+C EDGSF  VQC      CWCV  +G  + GS    +
Sbjct: 95  CRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK 154

Query: 89  PVAC 92
              C
Sbjct: 155 TPVC 158



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 299 TKCEVERFTATSFGHP-----YVPSCRRNGDYQAVQCQT-EGPCWCVDAQGKEMHGTRQQ 352
           +KC +ER  A           +VP C  +G +  VQC T  G CWCV   GK + G+  Q
Sbjct: 93  SKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ 152

Query: 353 GEPPSCA 359
            + P C+
Sbjct: 153 NKTPVCS 159



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 8/115 (6%)

Query: 50  PQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGR-PVACLSFCQLQKQQILLSGY 108
           P CA DG      C+     C          LG    GR   A  S C+L++ Q L    
Sbjct: 54  PICASDGRSYESMCEYQRAKC------RDPTLGVVHRGRCKDAGQSKCRLERAQALEQAK 107

Query: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS 163
               +  ++P+C + G +  VQC      CWCV  +G  + G+    +   C  S
Sbjct: 108 -KPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGS 161



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%)

Query: 606 QTCEQTP-ERLFVPSCTTEGSYEDVQCF--SGECWCV-NSWGKELPGSRVRGGQPRCPTD 661
           +  +Q P E + +P C   G Y+ VQC   +G CWCV    G+ LPG+  R   P C +D
Sbjct: 236 EEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD 295



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 12/112 (10%)

Query: 608 CEQTPERLFVPSCTTEGSYEDVQCFSGECWCVN-SWGKELPGSRVRGGQPRCPTDCEKQR 666
           C +T  +   P C ++G   +  C      C + + G    G     GQ +C  +     
Sbjct: 47  CSRTQPK---PICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLE----- 98

Query: 667 ARMQSLMGSQPAGSTLFVPACTSEGHFLPVQC--FNSECYCVDAEGQAIPGT 716
            R Q+L  ++     +FVP C  +G F  VQC  +   C+CV  +G+ I G+
Sbjct: 99  -RAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGS 149



 Score = 41.2 bits (95), Expect = 0.014
 Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 96  CQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAE-GMEVYGTRQL 154
           C  ++Q  L     N  +   +P+C   G Y PVQC      CWCV  + G  + GT   
Sbjct: 227 CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTR 286

Query: 155 GRPKRCPRSCEIRNRRLLHGVGDKSPPQCSAEGEFMPVQCKFVN--TTDMM 203
                C      +         D+  P C  EG+ M      ++  TTDM+
Sbjct: 287 YVMPSCESDARAKTTEADDPFKDRELPGC-PEGKKMEFITSLLDALTTDMV 336



 Score = 40.8 bits (94), Expect = 0.019
 Identities = 67/276 (24%), Positives = 102/276 (36%), Gaps = 54/276 (19%)

Query: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS-CEIR 167
           ++ + T   P C   G      C+ Q+ +C           G    GR K   +S C + 
Sbjct: 45  LHCSRTQPKPICASDGRSYESMCEYQRAKC------RDPTLGVVHRGRCKDAGQSKCRLE 98

Query: 168 NRRLLHGVGDKSP------PQCSAEGEFMPVQCKFVNTTDMMIFDLVHSYNRF-----PD 216
             + L     K P      P+C  +G F  VQC              H+Y  +     PD
Sbjct: 99  RAQALEQA--KKPQEAVFVPECGEDGSFTQVQC--------------HTYTGYCWCVTPD 142

Query: 217 AF-VTFSSFQRRFPEVSGYCHCAD-SQGRE-LAETGLELLLDEIYDTIFAGLDLPSTFTE 273
              ++ SS Q + P  SG       SQG     + G +         +F G ++    T 
Sbjct: 143 GKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEI----TA 198

Query: 274 TTLYRILQRRFLAVQSVISGRFRCPTK---CEVERFTATSFGHP------YVPSCRRNGD 324
            TL+  ++   +    + +   R   K   C+ ER +A             +P C   G 
Sbjct: 199 PTLW--IKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGL 256

Query: 325 YQAVQC-QTEGPCWCVDAQ-GKEMHGTRQQGEPPSC 358
           Y+ VQC Q+ G CWCV    G+ + GT  +   PSC
Sbjct: 257 YKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSC 292



 Score = 35.8 bits (81), Expect = 0.60
 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 645 ELPGSRVRGGQPRCPTDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE-- 702
           +L  + +R  +     D E+Q A  ++    Q     + +P C   G + PVQC  S   
Sbjct: 212 KLNNTNIRNSEKVYSCDQERQSALEEA---QQNPREGIVIPECAPGGLYKPVQCHQSTGY 268

Query: 703 CYCVDAE-GQAIPGTRSAIGKPKKCPTPCQLQSEQA 737
           C+CV  + G+ +PGT +    P  C +  + ++ +A
Sbjct: 269 CWCVLVDTGRPLPGTSTRYVMP-SCESDARAKTTEA 303



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 14/53 (26%), Positives = 28/53 (52%), Gaps = 6/53 (11%)

Query: 27  DAQPLRPCELQRETAFL------KQADYVPQCAEDGSFQTVQCQNDGRSCWCV 73
           +++ +  C+ +R++A        ++   +P+CA  G ++ VQC      CWCV
Sbjct: 220 NSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCV 272


>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
          Length = 131

 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 33/65 (50%), Positives = 44/65 (67%)

Query: 2318 DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDP 2377
            DGS LAA  +++VV   YR+G+FGF ++      GNW   DQVAAL+WVQ +I  FGGDP
Sbjct: 38   DGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDP 97

Query: 2378 RRVSL 2382
              V++
Sbjct: 98   SSVTI 102


>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
          Length = 993

 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 26/61 (42%), Positives = 34/61 (55%), Gaps = 2/61 (3%)

Query: 1456 GLGCVKCPEGSY--SQDEECIPCPVGFYQEQAGSLACVPCPVGRTTISAGAFSQTHCVTD 1513
            G  CV CP+G+Y   Q E+C+PCP G +QE+ G L+C  CP        GA + T C   
Sbjct: 633  GTKCVSCPQGTYYHGQTEQCVPCPAGTFQEREGQLSCDLCPGSDAHGPLGATNVTTCAGQ 692

Query: 1514 C 1514
            C
Sbjct: 693  C 693



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 26/57 (45%), Positives = 30/57 (52%), Gaps = 2/57 (3%)

Query: 1461 KCPEGSYSQD--EECIPCPVGFYQEQAGSLACVPCPVGRTTISAGAFSQTHCVTDCQ 1515
            +CP G +S D  + C PCP G YQ +AG   C PC  G TT   GA S   C T  Q
Sbjct: 692  QCPPGQHSVDGFKPCQPCPRGTYQPEAGRTLCFPCGGGLTTKHEGAISFQDCDTKVQ 748



 Score = 32.7 bits (73), Expect = 5.1
 Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 1/49 (2%)

Query: 1462 CPEGSYSQDEECIPCPVGFYQEQAGSLACVPCPVGRTTISAGAFSQTHC 1510
            C  G +    +C+ CP G Y     +  CVPCP G      G  S   C
Sbjct: 625  CRPGQHRAGTKCVSCPQGTYY-HGQTEQCVPCPAGTFQEREGQLSCDLC 672


>gi|115298674 nidogen 1 precursor [Homo sapiens]
          Length = 1247

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 9/118 (7%)

Query: 617 VPSCTTEGSYEDVQCFS--GECWCVNSWGKELPGSRVRGGQPRCPTDCEKQRARMQSLMG 674
           V  C     + D  C++  G   C    G +  G R   G+    T C+ +R  +    G
Sbjct: 803 VDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVE-KTRCQHEREHILGAAG 861

Query: 675 S----QPAGSTLFVPACTSEGHFLPVQCFNSE--CYCVDAEGQAIPGTRSAIGKPKKC 726
           +    +P    LFVP C + GH+ P QC  S   C+CVD +G+ + GTR+  G    C
Sbjct: 862 ATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPC 919



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/52 (46%), Positives = 32/52 (61%), Gaps = 1/52 (1%)

Query: 1025 GPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTT 1076
            G ++P+CDA G + P QCH  TG+CWCVD  G  + G+ T R    P C +T
Sbjct: 872  GLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRT-RPGMTPPCLST 922



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 49/171 (28%), Positives = 66/171 (38%), Gaps = 42/171 (24%)

Query: 26  VDAQPLRPCELQRETAFLKQADYVPQCA-EDGSFQTVQC----QNDGRSC---------- 70
           VD +P+  CE       + Q     QC    GS  T  C      DG++C          
Sbjct: 754 VDQRPINYCETGLHNCDIPQR---AQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSR 810

Query: 71  -----WCVGANGSEVLGSRQ--PGRPVACL------SFCQLQKQQILLSGYINSTDTS-- 115
                +C    GS     +    G    C+      + CQ +++ IL  G   +TD    
Sbjct: 811 CHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQHEREHIL--GAAGATDPQRP 868

Query: 116 -----YLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCP 161
                ++P+C   G YAP QC      CWCVD +G EV GTR   RP   P
Sbjct: 869 IPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRT--RPGMTP 917



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 27/60 (45%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 1159 RRVSPG-YVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQ-PACESPRCP 1216
            R + PG +VP C A  G ++P QC  + G CWCV   G EV GTR   G  P C S   P
Sbjct: 867  RPIPPGLFVPECDAH-GHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAP 925



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 23/50 (46%), Positives = 28/50 (56%), Gaps = 3/50 (6%)

Query: 612 PERLFVPSCTTEGSYEDVQCF--SGECWCVNSWGKELPGSRVRGGQ-PRC 658
           P  LFVP C   G Y   QC   +G CWCV+  G+E+ G+R R G  P C
Sbjct: 870 PPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPC 919



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 21/46 (45%), Positives = 27/46 (58%), Gaps = 2/46 (4%)

Query: 315 YVPSCRRNGDYQAVQCQ-TEGPCWCVDAQGKEMHGTR-QQGEPPSC 358
           +VP C  +G Y   QC  + G CWCVD  G+E+ GTR + G  P C
Sbjct: 874 FVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPC 919



 Score = 38.5 bits (88), Expect = 0.093
 Identities = 14/40 (35%), Positives = 21/40 (52%)

Query: 882 SYSDFSTPLAHFDLRNCWCVDEAGQELEGMRSEPSKLPTC 921
           ++  ++    H     CWCVD  G+E+EG R+ P   P C
Sbjct: 880 AHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPC 919



 Score = 37.0 bits (84), Expect = 0.27
 Identities = 36/126 (28%), Positives = 47/126 (37%), Gaps = 29/126 (23%)

Query: 1031 CDAFGSWEPVQCHA--------GTGHCWCVD--EKGGF--IPGSLTARSLQIPQCPTTCE 1078
            C      +P +CH         G+  C C    +  GF  +PG +           T C+
Sbjct: 800  CQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEK---------TRCQ 850

Query: 1079 KSRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAG--TWCVD----PASG 1132
              R   L ++   A   + P P  LFVP C   G YA  Q  G+    WCVD       G
Sbjct: 851  HEREHILGAAG--ATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEG 908

Query: 1133 EELRPG 1138
               RPG
Sbjct: 909  TRTRPG 914



 Score = 32.3 bits (72), Expect = 6.7
 Identities = 33/116 (28%), Positives = 45/116 (38%), Gaps = 20/116 (17%)

Query: 1453 SQDGLGCV---KCPEGSYSQDEECIPCPVGFYQE-----QAGSLACVPCPVGRTTISAGA 1504
            S DG  C    +C       D  C   P  F  +     Q     CVP  V +T      
Sbjct: 794  SGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQ--- 850

Query: 1505 FSQTHCV-----TDCQRN-EAGL---QCDQNGQYRASQKDRGSGKAFCVDGEGRRL 1551
              + H +     TD QR    GL   +CD +G Y  +Q    +G  +CVD +GR +
Sbjct: 851  HEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREV 906


>gi|93141003 testican 3 isoform 1 [Homo sapiens]
          Length = 433

 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 14/106 (13%)

Query: 999  QSTLSFYQRRRFSPDDSAGASALLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGF 1058
            Q+ LS  Q+R+       G   LL  G Y+P CD  G ++P QCH   G CWCVD  G  
Sbjct: 315  QTELSNIQKRQ-------GVKKLL--GQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNE 365

Query: 1059 IPGSLTARSLQIPQCPTTCEKSR--TSGLLSSWKQARSQENPSPKD 1102
            + GS   R   +  C    E S    SG    W      E+    D
Sbjct: 366  VMGS---RINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMND 408



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 6/85 (7%)

Query: 17  VSANIFEYQVDAQPLRPCELQRETAFLKQA------DYVPQCAEDGSFQTVQCQNDGRSC 70
           +S N + Y    Q   PC+ +      +Q        Y+P C EDG ++  QC      C
Sbjct: 297 ISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQC 356

Query: 71  WCVGANGSEVLGSRQPGRPVACLSF 95
           WCV   G+EV+GSR  G     + F
Sbjct: 357 WCVDRYGNEVMGSRINGVADCAIDF 381



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 22/57 (38%), Positives = 27/57 (47%)

Query: 96  CQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTR 152
           CQ +   I     +      Y+P C + G Y P QC     QCWCVD  G EV G+R
Sbjct: 314 CQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSR 370



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 1/41 (2%)

Query: 1165 YVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTG 1205
            Y+P C  EDG + P QC  + G CWCV   G EV G+R+ G
Sbjct: 334  YIPLCD-EDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRING 373



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 22/59 (37%), Positives = 35/59 (59%), Gaps = 5/59 (8%)

Query: 600 ETVLSSQTCEQTPERL---FVPSCTTEGSYEDVQCFS--GECWCVNSWGKELPGSRVRG 653
           +T LS+    Q  ++L   ++P C  +G Y+  QC    G+CWCV+ +G E+ GSR+ G
Sbjct: 315 QTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRING 373



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 26/109 (23%)

Query: 614 RLFVPSCTTEGSYEDVQCFSGE-CWCVNSWGKELPGSRVRGGQPRCPTDCE--KQRARMQ 670
           + F  SC T   Y+D    + E C+C             R   P C T+    ++R  ++
Sbjct: 283 KAFFNSCDT---YKDSLISNNEWCYCFQ-----------RQQDPPCQTELSNIQKRQGVK 328

Query: 671 SLMGSQPAGSTLFVPACTSEGHFLPVQCFNS--ECYCVDAEGQAIPGTR 717
            L+G        ++P C  +G++ P QC  S  +C+CVD  G  + G+R
Sbjct: 329 KLLGQ-------YIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSR 370



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 1/40 (2%)

Query: 315 YVPSCRRNGDYQAVQCQ-TEGPCWCVDAQGKEMHGTRQQG 353
           Y+P C  +G Y+  QC  + G CWCVD  G E+ G+R  G
Sbjct: 334 YIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRING 373


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116,021,967
Number of Sequences: 37866
Number of extensions: 5814878
Number of successful extensions: 13268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 12479
Number of HSP's gapped (non-prelim): 469
length of query: 2768
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2648
effective length of database: 13,703,598
effective search space: 36287127504
effective search space used: 36287127504
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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