Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 55749789
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo
sapiens]
(559 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens] 1137 0.0
gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens] 1070 0.0
gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo sapi... 626 e-179
gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo sapi... 550 e-156
gi|113205087 DENN/MADD domain containing 1C [Homo sapiens] 472 e-133
gi|154813195 DENN/MADD domain containing 2A [Homo sapiens] 162 8e-40
gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 152 1e-36
gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 152 1e-36
gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo sapi... 152 1e-36
gi|121949817 DENN/MADD domain containing 2C [Homo sapiens] 150 3e-36
gi|21361991 DENN/MADD domain containing 2D [Homo sapiens] 147 3e-35
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 88 2e-17
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 79 8e-15
gi|94818781 DENN/MADD domain containing 4C [Homo sapiens] 79 8e-15
gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi... 78 2e-14
gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi... 78 2e-14
gi|50345870 DENN/MADD domain containing 3 [Homo sapiens] 77 5e-14
gi|29788755 SET binding factor 2 [Homo sapiens] 74 3e-13
gi|239735519 SET binding factor 1 [Homo sapiens] 70 5e-12
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] 69 1e-11
gi|209863002 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|209862998 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|209862994 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|18860873 MAP-kinase activating death domain-containing protei... 49 1e-05
gi|209862987 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|209862983 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|209862979 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|209862975 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|209862971 MAP-kinase activating death domain-containing prote... 49 1e-05
gi|209571517 MAP-kinase activating death domain-containing prote... 49 1e-05
>gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens]
Length = 559
Score = 1137 bits (2941), Expect = 0.0
Identities = 559/559 (100%), Positives = 559/559 (100%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD
Sbjct: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT
Sbjct: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD
Sbjct: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
Query: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC
Sbjct: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
Query: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV
Sbjct: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
Query: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ
Sbjct: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
Query: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK
Sbjct: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
Query: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD
Sbjct: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
Query: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQNTIATPATLHILQK 540
PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQNTIATPATLHILQK
Sbjct: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQNTIATPATLHILQK 540
Query: 541 SITHFAAKFPTRGWTSSSH 559
SITHFAAKFPTRGWTSSSH
Sbjct: 541 SITHFAAKFPTRGWTSSSH 559
>gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]
Length = 1009
Score = 1070 bits (2766), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD
Sbjct: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT
Sbjct: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD
Sbjct: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
Query: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC
Sbjct: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
Query: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV
Sbjct: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
Query: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ
Sbjct: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
Query: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK
Sbjct: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
Query: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD
Sbjct: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
Query: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQ 526
PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQ
Sbjct: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQ 526
>gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo
sapiens]
Length = 755
Score = 626 bits (1614), Expect = e-179
Identities = 307/458 (67%), Positives = 371/458 (81%), Gaps = 5/458 (1%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
M R K NP+ TF++ ++V + DP V +FPED+ DQE+LQ++ KFCFPF V+
Sbjct: 1 MDCRTKANPDRTFDLVLKVKCHASEN--EDPVVLWKFPEDFGDQEILQSVPKFCFPFDVE 58
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
++ +QVGQ+FTFVLTDI+SKQRFGFCRL+SG C CILSYLPWFEV+YKLLN LADY
Sbjct: 59 RVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYL 118
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
K EN NE L +L+ P+P V+LSVHSYF PD LP+IPE+RNLTEYFVAVD
Sbjct: 119 AKELENDLNETLRSLYNHPVPKANTPVNLSVHSYFIAPDVTGLPTIPESRNLTEYFVAVD 178
Query: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
VNNML LYASML+ERRI+II SKLSTLTACIHGSAA+LYPMYWQH+YIPVLPPHLLDYCC
Sbjct: 179 VNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCC 238
Query: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
APMPYLIGIH SL+E+V+N +L+DVV+LNVDTNTLE+PF DL +LP+DV+S+LKN+LKK
Sbjct: 239 APMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQ 298
Query: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
ST TGDGVARAFL+AQAA FGSYR+AL+ +P EPITFCEE+FV H RS M+QFL+ A
Sbjct: 299 STATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKH-RSSVMKQFLETAIN 357
Query: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSD-KLYHQWLSTVRKGSGAILNTV 419
LQLFKQFIDGRL LN+G GFSDVFEEEI G + G + + Y QW+ TV+KG GA+ NT
Sbjct: 358 LQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGNPRSYQQWVHTVKKG-GALFNTA 416
Query: 420 KTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAEN 457
TKA PA++T YKFAK+HAK+G+KEVK++LK K+ E+
Sbjct: 417 MTKATPAVRTAYKFAKNHAKLGLKEVKSKLKHKENEED 454
>gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo
sapiens]
Length = 426
Score = 550 bits (1417), Expect = e-156
Identities = 276/425 (64%), Positives = 328/425 (77%), Gaps = 24/425 (5%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
M R K NP+ TF++ ++V + DP V +FPED+ DQE+LQ++ KFCFPF V+
Sbjct: 1 MDCRTKANPDRTFDLVLKVKCHASEN--EDPVVLWKFPEDFGDQEILQSVPKFCFPFDVE 58
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
++ +QVGQ+FTFVLTDI+SKQRFGFCRL+SG C CILSYLPWFEV+YKLLN LADY
Sbjct: 59 RVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYL 118
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSV--------------------HSYFTVPDT 160
K EN NE L +L+ P+P V+LSV HSYF PD
Sbjct: 119 AKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDV 178
Query: 161 RELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYP 220
LP+IPE+RNLTEYFVAVDVNNML LYASML+ERRI+II SKLSTLTACIHGSAA+LYP
Sbjct: 179 TGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYP 238
Query: 221 MYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFD 280
MYWQH+YIPVLPPHLLDYCCAPMPYLIGIH SL+E+V+N +L+DVV+LNVDTNTLE+PF
Sbjct: 239 MYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFS 298
Query: 281 DLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEE 340
DL +LP+DV+S+LKN+LKK ST TGDGVARAFL+AQAA FGSYR+AL+ +P EPITFCEE
Sbjct: 299 DLNNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEE 358
Query: 341 AFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEY-AGSDK 399
+FV H RS M+QFL+ A LQLFKQFIDGRL LN+G GFSDVFEEEI G + G DK
Sbjct: 359 SFVKH-RSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDK 417
Query: 400 LYHQW 404
L + +
Sbjct: 418 LQYDY 422
>gi|113205087 DENN/MADD domain containing 1C [Homo sapiens]
Length = 801
Score = 472 bits (1215), Expect = e-133
Identities = 253/528 (47%), Positives = 336/528 (63%), Gaps = 43/528 (8%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
M SR + F+ + E A P + DP + RQFP D+ DQE +Q + KFCFPF V+
Sbjct: 1 MESRAEGGSPAVFDWFFEAACPAS--LQEDPPILRQFPPDFRDQEAMQMVPKFCFPFDVE 58
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
S Q+FTF LTD+ +RFGFCRL +G +SC CILS+LPWFEVFYKLLN + D
Sbjct: 59 REPPSPAVQHFTFALTDLAGNRRFGFCRLRAGTQSCLCILSHLPWFEVFYKLLNTVGDLL 118
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTV----------------------P 158
+ Q + ELL+ L + + P SV L + S TV P
Sbjct: 119 AQDQVTEAEELLQNLFQQSLSGPQASVGLELGSGVTVSSGQGIPPPTRGNSKPLSCFVAP 178
Query: 159 DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAML 218
D+ LPSIPENRNLTE VAV N++ L+A++L ERR+L+ SKLSTLT+C+H S A+L
Sbjct: 179 DSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCALL 238
Query: 219 YPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETP 278
YPM W+HV IP LPPHLLDYCCAPMPYLIG+H SL E+VR AL+DVV+LNVD NTLET
Sbjct: 239 YPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVVLNVDANTLETT 298
Query: 279 FDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFC 338
F+D+Q+LP DV+S L+ RL+KV+ G+GV+R FLKAQA FG YR+AL P +P+TF
Sbjct: 299 FNDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFS 358
Query: 339 EEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEI-NMGEYAGS 397
EE F++ ++ F + A LQLFKQFI+ RL+ LN GEGFSD FE+EI G +G+
Sbjct: 359 EEVFLAQKPGAPLQAFHRRAVHLQLFKQFIEARLEKLNKGEGFSDQFEQEITGCGASSGA 418
Query: 398 DKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKD---I 454
+ Y W ++KG GA+L++VK K PA+K +Y+ AK G+K V++ L KD +
Sbjct: 419 LRSYQLWADNLKKGGGALLHSVKAKTQPAVKNMYR----SAKSGLKGVQSLLMYKDGDSV 474
Query: 455 AENGCAPTPEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRP 502
+ G + +P + ++ +L++ R PIT HFG+ RP RP
Sbjct: 475 LQRG----------GSLRAPALPSRSDRLQQ-RLPITQHFGKNRPLRP 511
>gi|154813195 DENN/MADD domain containing 2A [Homo sapiens]
Length = 1009
Score = 162 bits (410), Expect = 8e-40
Identities = 128/444 (28%), Positives = 212/444 (47%), Gaps = 55/444 (12%)
Query: 5 IKQNPETTFEVYVEVA-YPRTGGTLSDPEVQRQFP----------EDYSDQEVLQTLTKF 53
I+ FE +V V+ + + G PE+ +QFP + DQ L+ + +F
Sbjct: 557 IEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLERSFKFMREAEDQ--LKAIPQF 614
Query: 54 CFPFYVDSLTVSQ-VGQNFTFVLTDIDSKQRFGFCR-LSSGAKS-----CFCILSYLPWF 106
CFP D + V Q + F+FVLT D +RFG+CR L G K +CI+S L F
Sbjct: 615 CFPDAKDWVPVQQFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCF 674
Query: 107 EVFYKLLNILADYTTKRQENQ---WNELLETLHKLPIPDPGVSV----HLSVHSYFTVPD 159
+F ++L D KR+ L+ ++ + P P G ++ L +
Sbjct: 675 SLFSRIL----DEVEKRRGISPALVQPLMRSVMEAPFPALGKTILVKNFLPGSGTEVIEL 730
Query: 160 TRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLY 219
R L S E+ + F ++ V +++ ++AS+L ERR++ I KLS L+ C H A++Y
Sbjct: 731 CRPLDSRLEHVDFESLFSSLSVRHLVCVFASLLLERRVIFIADKLSILSKCCHAMVALIY 790
Query: 220 PMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPF 279
P WQH YIPVLPP ++D C+P P+LIG+ S + +R + L++V+++++ +
Sbjct: 791 PFAWQHTYIPVLPPAMVDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLVNSRFLRQM 850
Query: 280 DDLQS-LPNDVISSLKNRLKK-------------------VSTTTGDGVARAFLKAQAAF 319
DD S LP + +L++ L++ S+ + V+ AF++
Sbjct: 851 DDEDSILPRKLQVALEHILEQRNELACEQDEGPLDGRHGPESSPLNEVVSEAFVRFFVEI 910
Query: 320 FGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGE 379
G Y L E T EAF S ++R FL+ + Q+F+ FI R +
Sbjct: 911 VGHYSLFLTSGEREERTLQREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAK 970
Query: 380 GFSDV----FEEEINMGEYAGSDK 399
G +V + E + GE++G +K
Sbjct: 971 GLFEVRAQEYLETLPSGEHSGVNK 994
>gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapiens]
Length = 1137
Score = 152 bits (383), Expect = 1e-36
Identities = 107/379 (28%), Positives = 185/379 (48%), Gaps = 43/379 (11%)
Query: 31 PEVQRQFP-------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDSKQ 82
PEV QFP + +E L+ + +FCFP D L VS+ + F+F+LT D +
Sbjct: 716 PEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSR 775
Query: 83 RFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL----L 132
RFG+CR L SG +C++S L F +F K+L+ +R+ L +
Sbjct: 776 RFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLD-----EVERRRGISAALVYPFM 830
Query: 133 ETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENR----NLTEYFVAVDVNNMLHLY 188
+L + P P PG ++ + + EL ++R + F + V ++ ++
Sbjct: 831 RSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIF 890
Query: 189 ASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG 248
AS+L ERR++ + KLSTL++C H A+LYP WQH +IPVLP ++D C P P+L+G
Sbjct: 891 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVG 950
Query: 249 IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQS-LPNDVISSLKNRLKKVS------ 301
+ S + K++ + +++ +++N+ ++ DD + LP + ++L+ L++ +
Sbjct: 951 LLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQD 1010
Query: 302 ---------TTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMR 352
T V+ F++ G Y L + F EAF S ++R
Sbjct: 1011 SDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIR 1070
Query: 353 QFLQNATQLQLFKQFIDGR 371
+FL+ + Q+F FI R
Sbjct: 1071 RFLEVFMESQMFAGFIQDR 1089
>gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapiens]
Length = 1137
Score = 152 bits (383), Expect = 1e-36
Identities = 107/379 (28%), Positives = 185/379 (48%), Gaps = 43/379 (11%)
Query: 31 PEVQRQFP-------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDSKQ 82
PEV QFP + +E L+ + +FCFP D L VS+ + F+F+LT D +
Sbjct: 716 PEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSR 775
Query: 83 RFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL----L 132
RFG+CR L SG +C++S L F +F K+L+ +R+ L +
Sbjct: 776 RFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLD-----EVERRRGISAALVYPFM 830
Query: 133 ETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENR----NLTEYFVAVDVNNMLHLY 188
+L + P P PG ++ + + EL ++R + F + V ++ ++
Sbjct: 831 RSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIF 890
Query: 189 ASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG 248
AS+L ERR++ + KLSTL++C H A+LYP WQH +IPVLP ++D C P P+L+G
Sbjct: 891 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVG 950
Query: 249 IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQS-LPNDVISSLKNRLKKVS------ 301
+ S + K++ + +++ +++N+ ++ DD + LP + ++L+ L++ +
Sbjct: 951 LLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQD 1010
Query: 302 ---------TTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMR 352
T V+ F++ G Y L + F EAF S ++R
Sbjct: 1011 SDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIR 1070
Query: 353 QFLQNATQLQLFKQFIDGR 371
+FL+ + Q+F FI R
Sbjct: 1071 RFLEVFMESQMFAGFIQDR 1089
>gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo
sapiens]
Length = 717
Score = 152 bits (383), Expect = 1e-36
Identities = 107/379 (28%), Positives = 185/379 (48%), Gaps = 43/379 (11%)
Query: 31 PEVQRQFP-------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDSKQ 82
PEV QFP + +E L+ + +FCFP D L VS+ + F+F+LT D +
Sbjct: 296 PEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSR 355
Query: 83 RFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL----L 132
RFG+CR L SG +C++S L F +F K+L+ +R+ L +
Sbjct: 356 RFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLD-----EVERRRGISAALVYPFM 410
Query: 133 ETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENR----NLTEYFVAVDVNNMLHLY 188
+L + P P PG ++ + + EL ++R + F + V ++ ++
Sbjct: 411 RSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIF 470
Query: 189 ASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG 248
AS+L ERR++ + KLSTL++C H A+LYP WQH +IPVLP ++D C P P+L+G
Sbjct: 471 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVG 530
Query: 249 IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQS-LPNDVISSLKNRLKKVS------ 301
+ S + K++ + +++ +++N+ ++ DD + LP + ++L+ L++ +
Sbjct: 531 LLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQD 590
Query: 302 ---------TTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMR 352
T V+ F++ G Y L + F EAF S ++R
Sbjct: 591 SDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIR 650
Query: 353 QFLQNATQLQLFKQFIDGR 371
+FL+ + Q+F FI R
Sbjct: 651 RFLEVFMESQMFAGFIQDR 669
>gi|121949817 DENN/MADD domain containing 2C [Homo sapiens]
Length = 871
Score = 150 bits (379), Expect = 3e-36
Identities = 117/414 (28%), Positives = 206/414 (49%), Gaps = 49/414 (11%)
Query: 5 IKQNPETTFEVYVEVAYPRTGGTLSD-PEVQRQFP--------EDYSDQEVLQTLTKFCF 55
I+ + FE++V V+ + +S P+V +QFP + +E L+ + KFCF
Sbjct: 426 IELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCF 485
Query: 56 PFYVDSLTVSQV-GQNFTFVLTDIDSKQRFGFCR----LSSGAK--SCFCILSYLPWFEV 108
P D + S++ + F+FVLT D + FG+C+ + G + +C++S L F +
Sbjct: 486 PDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNL 545
Query: 109 FYKLLNILADYTTKRQENQ---WNELLETLHKLPIPDPGVSVHLSVHSYF------TVPD 159
F K+L D KR+E + ++ + P P PG ++ +V SY ++
Sbjct: 546 FSKIL----DEVEKRREMSPALVYPFMRSVMEAPFPAPGRTI--TVKSYLPGAGDESIEL 599
Query: 160 TRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLY 219
R L S E+ + F + V +++ + AS+L ERR++ + + LSTL+ C H A LY
Sbjct: 600 CRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLY 659
Query: 220 PMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNT-LETP 278
P WQH YIPVLP ++D C+P P+LIGI + +++++ +++V+I+++ + L+
Sbjct: 660 PFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEV 719
Query: 279 FDDLQSLP--------------NDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYR 324
D+ + LP N++++ +N + V T V+ AF++ G Y
Sbjct: 720 SDEDEILPPKLQAALMQILEERNEILTQEQNFSQDV--TLNSLVSEAFVRFFVELVGHYS 777
Query: 325 NALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSG 378
+ + F E F + S ++R FL + Q+F FI R +L SG
Sbjct: 778 LNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDR-ELRKSG 830
>gi|21361991 DENN/MADD domain containing 2D [Homo sapiens]
Length = 471
Score = 147 bits (371), Expect = 3e-35
Identities = 107/393 (27%), Positives = 193/393 (49%), Gaps = 44/393 (11%)
Query: 30 DPEVQRQFP--------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDS 80
+P + QFP + ++ +L+ + FCFP + ++++ + F+FVLT++D
Sbjct: 72 EPIITYQFPKRENLLRGQQEEEERLLKAIPLFCFPDGNEWASLTEYPRETFSFVLTNVDG 131
Query: 81 KQRFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL--- 131
++ G+CR L +G +CI+S + F +F K+L D KR + +
Sbjct: 132 SRKIGYCRRLLPAGPGPRLPKVYCIISCIGCFGLFSKIL----DEVEKRHQISMAVIYPF 187
Query: 132 LETLHKLPIPDPGVSVHLSVHSYFTVPD--------TRELPSIPENRNLTEYFVAVDVNN 183
++ L + P PG +V L +PD TR L S E+ + + +
Sbjct: 188 MQGLREAAFPAPGKTVTLKSF----IPDSGTEFISLTRPLDSHLEHVDFSSLLHCLSFEQ 243
Query: 184 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPM 243
+L ++AS + ER+I+ + LSTL+ CIH +AA+LYP W H YIPV+P LL C P
Sbjct: 244 ILQIFASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPT 303
Query: 244 PYLIGIHLSLMEKVRNMALDDVVILNVDTNT-LETPFDDLQSLP----NDVISSLKNRLK 298
P+++G+ + ++V + +++V+++N+ T L + D+ LP +D++ SL +
Sbjct: 304 PFMVGVQMRFQQEVMDSPMEEVLLVNLCEGTFLMSVGDEKDILPPKLQDDILDSLGQGIN 363
Query: 299 KVSTT--TGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQ 356
++ T + V+ F++ G Y + +K E F E +F S R+F++
Sbjct: 364 ELKTAEQINEHVSGPFVQFFVKIVGHYASYIKREANGQGHFQERSFCKALTSKTNRRFVK 423
Query: 357 NATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEI 389
+ QLF FI N G+ F+++I
Sbjct: 424 KFVKTQLFSLFIQEAEKSKNPPAGY---FQQKI 453
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 88.2 bits (217), Expect = 2e-17
Identities = 61/224 (27%), Positives = 106/224 (47%), Gaps = 15/224 (6%)
Query: 76 TDIDSKQRFGFCRLSSGA---KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQW---N 129
T + QRF +S C C+++ + + + +L L T Q +
Sbjct: 183 TPVTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLEQLHQAVTSPQPPPLPLES 242
Query: 130 ELLETLHKLPIPDPGVSVHLS-VHSYFTV--PDTRELPSIPENRNLTEYFVAVDVNNMLH 186
+ L+++P+P PG S+ S V+ P T ELP + + E F + V N+
Sbjct: 243 YIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLF--DFPVKEVFELLGVENVFQ 300
Query: 187 LYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL 246
L+ L E +IL+ L A+++P WQHVY+P+LP LL + AP+PYL
Sbjct: 301 LFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYL 360
Query: 247 IGIHLSLMEKVRNMALD---DVVILNVDTNTLETPFDDLQSLPN 287
+G+H + ++ + L ++ +++D + +E P +DL PN
Sbjct: 361 MGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELP-EDLPQFPN 403
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 79.3 bits (194), Expect = 8e-15
Identities = 62/241 (25%), Positives = 109/241 (45%), Gaps = 15/241 (6%)
Query: 59 VDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILAD 118
+DSL S + + T L + + R + C+++ LP+ + K L L
Sbjct: 155 MDSLA-SSLDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYK 213
Query: 119 YTTKRQENQW---NELLETLHKLPIPDPGVSVHLSVHSYFTV----PDTRELPSIPENRN 171
T +Q + + L+++P+P PG S+ Y V P ELP +
Sbjct: 214 AVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKF-YGVYEPVICQRPGPSELPL--SDYP 270
Query: 172 LTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVL 231
L E F + + N++ ++ +L E +IL+ L G +L+P WQHVY+P+L
Sbjct: 271 LREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPIL 330
Query: 232 PPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD---DVVILNVDTNTLETPFDDLQSLPND 288
P LL + AP+PYL+G+ + L ++ +++D + +E P ++ PN
Sbjct: 331 PASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELP-EEFPQFPNK 389
Query: 289 V 289
V
Sbjct: 390 V 390
>gi|94818781 DENN/MADD domain containing 4C [Homo sapiens]
Length = 1673
Score = 79.3 bits (194), Expect = 8e-15
Identities = 79/328 (24%), Positives = 127/328 (38%), Gaps = 51/328 (15%)
Query: 90 SSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG--- 144
S C C+LS+ P+FE F K L + + E + + +P P P
Sbjct: 70 SINTNKCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPR 129
Query: 145 VSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKL 204
+ V LSVH + P N + + + N L +L E +IL+ +
Sbjct: 130 ILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRP 189
Query: 205 STLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDD 264
+ LT AM++P WQ YIP+ P L AP+P+++G+ + + D
Sbjct: 190 AVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFD--LHDPPQD 247
Query: 265 VVILNVDTNTL----ETPFDDLQSLPNDVISSLKNRLKK-------VSTTTGDG------ 307
VV +++DTN L E + + LP +L + LKK V T +G
Sbjct: 248 VVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMT 307
Query: 308 ------------------VARAFLKAQAAFFGSYRNALKIEPEEPIT--------FCEEA 341
+ AFL+ A+ YR L+ E P F +
Sbjct: 308 PIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQG 367
Query: 342 FVSHYRSGAMRQFLQNATQLQLFKQFID 369
F+ R A +F ++ Q+F +FI+
Sbjct: 368 FLKS-RDRAYAKFYTLLSKTQIFIRFIE 394
>gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo
sapiens]
Length = 1906
Score = 78.2 bits (191), Expect = 2e-14
Identities = 89/377 (23%), Positives = 146/377 (38%), Gaps = 59/377 (15%)
Query: 42 SDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILS 101
S ++V +F P+ ++LT Q LT D K + C C+LS
Sbjct: 264 SAEKVYGAAIQFYEPYSEENLTEKQ---RLLLGLTSADGKSDSS---KTIHTNKCICLLS 317
Query: 102 YLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG---VSVHLSVHSYFT 156
+ P+F+ F K L L Y+ E + +HK+P P P + V LS H
Sbjct: 318 HWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLI 377
Query: 157 VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAA 216
+ P + + N + L + E +ILI + S LT+ +
Sbjct: 378 LSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVS 437
Query: 217 MLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLE 276
M++P +W Y+P+ P L D AP P+++GI + DV ++VDTNT+
Sbjct: 438 MIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYD--PPPDVSCVDVDTNTIS 495
Query: 277 ------------TPFDDLQSLPNDVISSLKNRLKKVSTTTGDG----------------- 307
P ++L N +++L +L K+ D
Sbjct: 496 QIGDKKNVAWKILPKKPCKNLMN-TLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKR 554
Query: 308 -------VARAFLKAQAAFFGSYRNALK---IEPEEPIT-----FCEEAFVSHYRSGAMR 352
+ AFL A+ YR+ L+ P E T F +AF+ R + +
Sbjct: 555 LHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFL-RSRDRSHQ 613
Query: 353 QFLQNATQLQLFKQFID 369
+F T+ Q+F +FI+
Sbjct: 614 KFYNMMTKTQMFIRFIE 630
>gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo
sapiens]
Length = 1863
Score = 78.2 bits (191), Expect = 2e-14
Identities = 89/377 (23%), Positives = 146/377 (38%), Gaps = 59/377 (15%)
Query: 42 SDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILS 101
S ++V +F P+ ++LT Q LT D K + C C+LS
Sbjct: 264 SAEKVYGAAIQFYEPYSEENLTEKQ---RLLLGLTSADGKSDSS---KTIHTNKCICLLS 317
Query: 102 YLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG---VSVHLSVHSYFT 156
+ P+F+ F K L L Y+ E + +HK+P P P + V LS H
Sbjct: 318 HWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLI 377
Query: 157 VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAA 216
+ P + + N + L + E +ILI + S LT+ +
Sbjct: 378 LSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVS 437
Query: 217 MLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLE 276
M++P +W Y+P+ P L D AP P+++GI + DV ++VDTNT+
Sbjct: 438 MIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYD--PPPDVSCVDVDTNTIS 495
Query: 277 ------------TPFDDLQSLPNDVISSLKNRLKKVSTTTGDG----------------- 307
P ++L N +++L +L K+ D
Sbjct: 496 QIGDKKNVAWKILPKKPCKNLMN-TLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKR 554
Query: 308 -------VARAFLKAQAAFFGSYRNALK---IEPEEPIT-----FCEEAFVSHYRSGAMR 352
+ AFL A+ YR+ L+ P E T F +AF+ R + +
Sbjct: 555 LHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFL-RSRDRSHQ 613
Query: 353 QFLQNATQLQLFKQFID 369
+F T+ Q+F +FI+
Sbjct: 614 KFYNMMTKTQMFIRFIE 630
>gi|50345870 DENN/MADD domain containing 3 [Homo sapiens]
Length = 1198
Score = 76.6 bits (187), Expect = 5e-14
Identities = 72/286 (25%), Positives = 124/286 (43%), Gaps = 32/286 (11%)
Query: 47 LQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFG------------FC----RLS 90
L TL + CFP V T + VLTD+ + +G +C +
Sbjct: 39 LLTLPQLCFPGGVCVATEPKEDCVHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKTH 98
Query: 91 SGAKSCF-----CILSYLPWF----EVFYKLLNILADYTTKRQENQWNELLETLHKLPIP 141
CF C++S P++ + LL +L ++ + L +P P
Sbjct: 99 RECPGCFVPFAVCVVSRFPYYNSLKDCLSCLLALLKPCKDFEVDSHIKDFAAKLSLIPSP 158
Query: 142 DPGVSVHL--SVHSYFTVPDTRELPSIPE-NRNLTEYFVAVDVNNMLHLYASMLYERRIL 198
PG +HL ++ S V R P P + +L + +L + +L E+RI+
Sbjct: 159 PPG-PLHLVFNMKSLQIVLPARADPESPILDLDLHLPLLCFRPEKVLQILTCILTEQRIV 217
Query: 199 IICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVR 258
S + LT A LYP+ WQH ++P+L +LD+ AP +L+G HL E+V
Sbjct: 218 FFSSDWALLTLVTECFMAYLYPLQWQHPFVPILSDQMLDFVMAPTSFLMGCHLDHFEEVS 277
Query: 259 NMALDDVVILNVD--TNTLETPFDDLQSLPNDVISSLKNRLKKVST 302
A D +V++N+D + T DD +P+ + + + +++V +
Sbjct: 278 KEA-DGLVLINIDHGSITYSKSTDDNVDIPDVPLLAAQTFIQRVQS 322
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 74.3 bits (181), Expect = 3e-13
Identities = 91/418 (21%), Positives = 155/418 (37%), Gaps = 68/418 (16%)
Query: 33 VQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFC----- 87
+QR +D+ D Q + FC P + F VLTDIDS + + C
Sbjct: 28 IQRFPQKDWDDTPFPQGIELFCQPGGWQLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYE 87
Query: 88 -----------RLSSGAK-------------SCFCILSYLPWFEVFYKLLNILADYTTKR 123
+ AK ++S L + E+F L ++
Sbjct: 88 AEINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACLGLIYTVYVDS 147
Query: 124 QENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNL-------TEYF 176
L+ L +P G S L + R+L P + +L F
Sbjct: 148 LNVSLESLIANLCACLVPAAGGSQKL----FSLGAGDRQLIQTPLHDSLPITGTSVALLF 203
Query: 177 VAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLL 236
+ + N+L L+ ++L E ++L + L+ ++++P+ + + YIP+LP LL
Sbjct: 204 QQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLL 263
Query: 237 DYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETP-FDDLQSLPNDVISSLKN 295
+ +P P++IG+H V + DV+I ++D T++ P L SLP ++ ++
Sbjct: 264 EVLSSPTPFIIGVHSVFKTDVHELL--DVIIADLDGGTIKIPECIHLSSLPEPLLHQTQS 321
Query: 296 RLKKV---------------------STTTGDGVARAFLKAQAAFFGSYRNAL---KIEP 331
L + S V FL+ A F YR+ L +I
Sbjct: 322 ALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHA 381
Query: 332 EEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEI 389
E I F + AF+ R FL F F+ R S + F ++ E+
Sbjct: 382 EPVIHFHKTAFLGQ-RGLVENDFLTKVLSGMAFAGFVSERGPPYRSCDLFDELVAFEV 438
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 70.1 bits (170), Expect = 5e-12
Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 29/233 (12%)
Query: 165 SIPENR-NLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYW 223
S+P +R ++ F + + N+L L+ + L E ++L + L G A+L+P+ +
Sbjct: 203 SLPVSRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRY 262
Query: 224 QHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPF---- 279
Y+P+LP LL+ P P++IG++ + + + + DV++ ++D T+ P
Sbjct: 263 SFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAETQELL--DVIVADLDGGTVTIPECVHI 320
Query: 280 ----DDLQSLPNDVISSLKN--------RLKKVSTTTG-----DGVARA-FLKAQAAFFG 321
+ LQS + V+S + + +T+T D RA FL+ A
Sbjct: 321 PPLPEPLQSQTHSVLSMVLDPELELADLAFPPPTTSTSSLKMQDKELRAVFLRLFAQLLQ 380
Query: 322 SYR---NALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGR 371
YR + ++I PE I F + AF+ R FL + F F+ R
Sbjct: 381 GYRWCLHVVRIHPEPVIRFHKAAFLGQ-RGLVEDDFLMKVLEGMAFAGFVSER 432
>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
Length = 1496
Score = 68.6 bits (166), Expect = 1e-11
Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 7/188 (3%)
Query: 93 AKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG---VSV 147
++ +LS P F F L L Y+ E + +H +P P P + V
Sbjct: 314 SRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILV 373
Query: 148 HLSVHSYFTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTL 207
+S + + P + + ++ + L ++L E ++L+ + L
Sbjct: 374 QMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLL 433
Query: 208 TACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVI 267
T+ +M++P++WQ YIP+ P L D AP+P+++GIH S + A DV+
Sbjct: 434 TSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPA--DVIC 491
Query: 268 LNVDTNTL 275
+++DTNTL
Sbjct: 492 VDLDTNTL 499
>gi|209863002 MAP-kinase activating death domain-containing protein
isoform j [Homo sapiens]
Length = 1541
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209862998 MAP-kinase activating death domain-containing protein
isoform i [Homo sapiens]
Length = 1544
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209862994 MAP-kinase activating death domain-containing protein
isoform d [Homo sapiens]
Length = 1647
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|18860873 MAP-kinase activating death domain-containing protein
isoform g [Homo sapiens]
Length = 1581
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209862987 MAP-kinase activating death domain-containing protein
isoform f [Homo sapiens]
Length = 1479
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209862983 MAP-kinase activating death domain-containing protein
isoform e [Homo sapiens]
Length = 1608
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209862979 MAP-kinase activating death domain-containing protein
isoform c [Homo sapiens]
Length = 1545
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209862975 MAP-kinase activating death domain-containing protein
isoform b [Homo sapiens]
Length = 1565
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209862971 MAP-kinase activating death domain-containing protein
isoform a [Homo sapiens]
Length = 1588
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
>gi|209571517 MAP-kinase activating death domain-containing protein
isoform h [Homo sapiens]
Length = 1587
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214
F +PD + +L + VD L + +L E ++++ + L+ +
Sbjct: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339
Query: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270
AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++
Sbjct: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399
Query: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299
D+N + P + L LP LK LK+
Sbjct: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,038,067
Number of Sequences: 37866
Number of extensions: 1053367
Number of successful extensions: 2927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2799
Number of HSP's gapped (non-prelim): 122
length of query: 559
length of database: 18,247,518
effective HSP length: 107
effective length of query: 452
effective length of database: 14,195,856
effective search space: 6416526912
effective search space used: 6416526912
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.