BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55749431 transcription elongation factor A (SII)-like 3 [Homo sapiens] (200 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 419 e-117 gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 419 e-117 gi|61175239 transcription elongation factor A (SII)-like 5 [Homo... 376 e-105 gi|118600971 transcription elongation factor A (SII)-like 6 [Hom... 354 2e-98 gi|55749459 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46 gi|55749442 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46 gi|65505873 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46 gi|55749451 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46 gi|17933774 transcription elongation factor A (SII)-like 2 [Homo... 171 3e-43 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 60 1e-09 gi|55749466 transcription elongation factor A (SII)-like 8 [Homo... 56 2e-08 gi|23503247 transcription elongation factor A (SII)-like 8 [Homo... 56 2e-08 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 3e-08 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 54 7e-08 gi|55956788 nucleolin [Homo sapiens] 54 1e-07 gi|21361639 DIPB protein [Homo sapiens] 50 1e-06 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 50 1e-06 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 2e-06 gi|17975763 myelin transcription factor 1 [Homo sapiens] 49 3e-06 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 49 3e-06 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 49 3e-06 gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 48 6e-06 gi|55743140 WW domain binding protein 5 [Homo sapiens] 47 8e-06 gi|55743147 WW domain binding protein 5 [Homo sapiens] 47 8e-06 gi|10047100 WW domain binding protein 5 [Homo sapiens] 47 8e-06 gi|55743145 WW domain binding protein 5 [Homo sapiens] 47 8e-06 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 47 1e-05 gi|148746195 trichohyalin [Homo sapiens] 47 1e-05 gi|171916097 repetin [Homo sapiens] 47 1e-05 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 47 1e-05 >gi|55749431 transcription elongation factor A (SII)-like 3 [Homo sapiens] Length = 200 Score = 419 bits (1076), Expect = e-117 Identities = 200/200 (100%), Positives = 200/200 (100%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD Sbjct: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG Sbjct: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180 Query: 181 VRGVRGGGRGQRGLHDIPYL 200 VRGVRGGGRGQRGLHDIPYL Sbjct: 181 VRGVRGGGRGQRGLHDIPYL 200 >gi|14249718 transcription elongation factor A (SII)-like 3 [Homo sapiens] Length = 200 Score = 419 bits (1076), Expect = e-117 Identities = 200/200 (100%), Positives = 200/200 (100%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD Sbjct: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG Sbjct: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180 Query: 181 VRGVRGGGRGQRGLHDIPYL 200 VRGVRGGGRGQRGLHDIPYL Sbjct: 181 VRGVRGGGRGQRGLHDIPYL 200 >gi|61175239 transcription elongation factor A (SII)-like 5 [Homo sapiens] Length = 206 Score = 376 bits (966), Expect = e-105 Identities = 182/206 (88%), Positives = 191/206 (92%), Gaps = 6/206 (2%) Query: 1 MEKPYNKNEG------NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEP 54 MEK Y +NEG NLE+EGKPEDE +DEGKSDEEEKPD+EGKTECEGKREDEGEP Sbjct: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 Query: 55 GDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 114 GDEGQLEDEG+QEKQG+SEGE KPQ EGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT Sbjct: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120 Query: 115 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 174 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA Sbjct: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180 Query: 175 PRGQRGVRGVRGGGRGQRGLHDIPYL 200 PRGQRGVRGVRGGGRGQ+ L D+PY+ Sbjct: 181 PRGQRGVRGVRGGGRGQKDLEDVPYV 206 >gi|118600971 transcription elongation factor A (SII)-like 6 [Homo sapiens] Length = 183 Score = 354 bits (909), Expect = 2e-98 Identities = 171/183 (93%), Positives = 175/183 (95%), Gaps = 1/183 (0%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPD EGKTECEGKR+ EGEPGDEGQL Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDAEGKTECEGKRKAEGEPGDEGQL 60 Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 ED+GSQEKQG+SEGEGKPQGEGKPASQAKPE QPRAAEKRPA DYVPRKAKRKTDRGTDD Sbjct: 61 EDKGSQEKQGKSEGEGKPQGEGKPASQAKPEGQPRAAEKRPAGDYVPRKAKRKTDRGTDD 120 Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA +G G Sbjct: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA-QGDNG 179 Query: 181 VRG 183 V G Sbjct: 180 VSG 182 >gi|55749459 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 182 bits (462), Expect = 2e-46 Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51 MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104 G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200 WMQR++QDPF PRG R RG G +R + DIPY+ Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|55749442 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 182 bits (462), Expect = 2e-46 Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51 MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104 G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200 WMQR++QDPF PRG R RG G +R + DIPY+ Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|65505873 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 182 bits (462), Expect = 2e-46 Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51 MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104 G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200 WMQR++QDPF PRG R RG G +R + DIPY+ Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|55749451 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 182 bits (462), Expect = 2e-46 Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51 MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104 G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200 WMQR++QDPF PRG R RG G +R + DIPY+ Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|17933774 transcription elongation factor A (SII)-like 2 [Homo sapiens] Length = 227 Score = 171 bits (434), Expect = 3e-43 Identities = 95/229 (41%), Positives = 138/229 (60%), Gaps = 31/229 (13%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD----------------------------E 32 MEK +N+NEG N+GK ++E +P EGK + + Sbjct: 1 MEKLFNENEGMPSNQGKIDNEEQPPHEGKPEVACILEDKKLENEGNTENTGKRVEEPLKD 60 Query: 33 EEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPES 92 +EKP+ GK + EGK E +G+ +G + EG E+ GR+EGEG+P E +P S+ +PES Sbjct: 61 KEKPESAGKAKGEGKSERKGKSEMQGGSKTEGKPERGGRAEGEGEPDSEREPESEGEPES 120 Query: 93 QPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152 + RAA KRPAED +PRKAKRKT++G K +E + + + S+E+M+RE +++R +++ Sbjct: 121 ETRAAGKRPAEDDIPRKAKRKTNKGLAQYLKQYKEAIHDMNFSNEDMIREFDNMARVEDK 180 Query: 153 LRK-KQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200 RK KQK+G F WMQR++QDPF PRG R RG G +R DIPY+ Sbjct: 181 RRKSKQKLGAFLWMQRNLQDPFYPRGPREFRG--GCRAPRRDTEDIPYV 227 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 60.1 bits (144), Expect = 1e-09 Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 18/184 (9%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKT-ECEGKREDEGEPGDEGQLEDEGSQEKQGR 71 E EG+ E E ++EG+ + EE+ + EG+ E EG+ E+ G+E + E+EG +E +G Sbjct: 950 EEEGEWEGE---EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006 Query: 72 SEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQE 131 EGEG+ + E + + + E + E E + + K G ++ +E+ +E Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066 Query: 132 ---RHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGGG 188 + EE R+ G+ + +++ K G Q+ + V +G G Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQK-----------KSVTNTQGNG 1115 Query: 189 RGQR 192 + QR Sbjct: 1116 KEQR 1119 Score = 56.6 bits (135), Expect = 1e-08 Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 29/180 (16%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEG-KTECEGKREDEGEPGD---- 56 E+ + EG E EG+ E+E EG+ + EE+ + EG + E EGK E+EGE G+ Sbjct: 879 EEEEGEGEGEEEGEGEGEEE-----EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGE 933 Query: 57 ----EGQLED---EGSQE------KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103 EG+ ED EG +E ++ EGEG+ +GEG+ + + E + E E Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE-GEEGEGEGEEEEGEGEGEE 992 Query: 104 DYVPRKAKRKTDRGTDDSPKDSQEDLQ---ERHLSSEEMMRECGDVSRAQEELRKKQKMG 160 + + + + + G ++ + +E+ + E + EE E G+ +EE +++K G Sbjct: 993 EEGEEEGEEEGE-GEEEGEGEGEEEEEGEVEGEVEGEEGEGE-GEEEEGEEEGEEREKEG 1050 Score = 56.2 bits (134), Expect = 2e-08 Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 13/161 (8%) Query: 6 NKNEGNLENEGKPEDEVEPDDEGKS-DEEEKPDVEGKTECEGKREDEGEPGDEGQL---- 60 +K G +E G+ E E+ +E K D EE+ E + + +R E E G E + Sbjct: 680 DKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGE 739 Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 E+EG +E++ EGEGK +GEG+ + + E + E++ E R K + D Sbjct: 740 EEEGDREEEEEKEGEGKEEGEGE---EVEGEREKEEGERKKEE----RAGKEEKGEEEGD 792 Query: 121 SPKDSQEDLQERHLSSEEMMR-ECGDVSRAQEELRKKQKMG 160 + +E+ + R EE E G+V + E ++++ G Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833 Score = 56.2 bits (134), Expect = 2e-08 Identities = 43/140 (30%), Positives = 73/140 (52%), Gaps = 12/140 (8%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKR---EDEGEPGD-EGQLED 62 + E E EG+ E+ ++EG+ +EEE EGK E EG+ E+EGE G+ EG+ E+ Sbjct: 826 REEEEEEGEGEEEEGEGEEEEGEGEEEEG---EGKGEEEGEEGEGEEEGEEGEGEGEEEE 882 Query: 63 -EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT--- 118 EG E++G EGE + +GEG+ + + E + E + E+ + + + + G Sbjct: 883 GEGEGEEEGEGEGE-EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941 Query: 119 DDSPKDSQEDLQERHLSSEE 138 +D + +E+ E EE Sbjct: 942 EDGEGEGEEEEGEWEGEEEE 961 Score = 53.1 bits (126), Expect = 2e-07 Identities = 40/156 (25%), Positives = 70/156 (44%), Gaps = 13/156 (8%) Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGS 65 ++ E N E E E+E +E + D EE+ + EG EGK E EGE + + ++EG Sbjct: 719 HQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG----EGKEEGEGEEVEGEREKEEGE 774 Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPA---------EDYVPRKAKRKTDR 116 ++K+ R+ E K + EG + E++ R EK E R+ + + Sbjct: 775 RKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE 834 Query: 117 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152 G ++ + +E+ + E E G+ +EE Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870 Score = 50.8 bits (120), Expect = 7e-07 Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 5/147 (3%) Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE-CEGKREDEGEPGDEGQLEDEGSQE 67 EG E EG+ + ++EG+ + EE+ + EG+ E EG+ E+EGE G+ + E EG E Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE-GEGEEEEGEGKGE 922 Query: 68 KQG-RSEGEG-KPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125 ++G EGEG + +GEG+ + E + E E+ + + + + ++ + Sbjct: 923 EEGEEGEGEGEEEEGEGE-GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981 Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEE 152 +E+ E EE E + +EE Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEE 1008 Score = 50.1 bits (118), Expect = 1e-06 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 2/98 (2%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 E+ + EG E E + E EVE + EG+ E E + EG+ E E +RE EGE G+E + Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE-EREKEGE-GEENRRN 1058 Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEK 99 E +E++G+ + G+ + E + + K S+ + + K Sbjct: 1059 REEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096 Score = 49.3 bits (116), Expect = 2e-06 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 10/98 (10%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKT-----ECEGKREDEGEPGDEGQLE 61 + EG E E + E E E + EG +EEE+ +VEG+ E EG+ E+ E G+E + E Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEG--EEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049 Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEK 99 EG + ++ R E E + EGK + E++ + E+ Sbjct: 1050 GEGEENRRNREEEE---EEEGKYQETGEEENERQDGEE 1084 Score = 46.2 bits (108), Expect = 2e-05 Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 23/174 (13%) Query: 1 MEKPYNKNEGNLENE---GKPEDEVEPDDEGKSDEEEKP----------DVEG--KTECE 45 +E K EG + E GK E E D+G+ +EEE +VEG E + Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823 Query: 46 GKREDEGEPG----DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKR- 100 G+RE+E E G +EG+ E+E + ++ EG+G+ +GE + E + E+ Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883 Query: 101 --PAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152 E+ + + + G + + + + +E EE E G+ +EE Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE-GEGEGEEEE 936 Score = 42.4 bits (98), Expect = 3e-04 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 7/142 (4%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEE--EKPDVEGKTECEGKREDEGEPGDEGQ 59 ++ + K +G E E K ++ + + EE E+ EG+ E EG RE+E E EG+ Sbjct: 699 KEEWKKRDGE-EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEE-EGDREEEEEKEGEGK 756 Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKR---KTDR 116 E EG + + R + EG+ + E + + K E + E E + K + + Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG 816 Query: 117 GTDDSPKDSQEDLQERHLSSEE 138 G + K +E+ +E EE Sbjct: 817 GEVEEGKGEREEEEEEGEGEEE 838 Score = 41.6 bits (96), Expect = 5e-04 Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 3/162 (1%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 EK + E + +G+ +++ E + + + ++ + G+ E E+EG+ +E + E Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752 Query: 62 DEGSQEKQGRS-EGE-GKPQGEGKPASQA-KPESQPRAAEKRPAEDYVPRKAKRKTDRGT 118 EG +E +G EGE K +GE K +A K E ++ E+ + + G Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812 Query: 119 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMG 160 + + +E ER EE E + +EE +++ G Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG 854 Score = 41.6 bits (96), Expect = 5e-04 Identities = 38/155 (24%), Positives = 67/155 (43%), Gaps = 6/155 (3%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKR---EDEGEPGDEG 58 E+ + EG E EG+ + +EG+ +EE+ E K E EG + E+E G G Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG-RG 805 Query: 59 QLEDEGSQEKQGR-SEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRG 117 + ++EG + + G EG+G+ + E + + E + E E+ K + + + G Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865 Query: 118 TDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152 + + E E E E G+ +EE Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEE-GEGEGEEEE 899 Score = 40.4 bits (93), Expect = 0.001 Identities = 51/226 (22%), Positives = 94/226 (41%), Gaps = 37/226 (16%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKRED----------- 50 E+ NE N++ G +++ E + +D+ E EGK + G+ ED Sbjct: 603 EQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVS--EGKAKSVGEAEDGPEGRGDGTCE 660 Query: 51 EGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPR---AAEKRPAEDYVP 107 EG G E ++E + ++ + GE + GEG+ K E + R E++ E Sbjct: 661 EGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQ 720 Query: 108 RKAKRKTDRGTDDSPKDSQEDLQERHLSSE--------------EMMRECGDVSRAQEEL 153 ++ ++ + G ++ + +E+ +R E E RE + R +EE Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780 Query: 154 RKKQKMGGFHWMQRD-VQDPFAPRGQRGVRG--VRGG----GRGQR 192 K++ G Q + ++ RG+ G V GG G+G+R Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826 >gi|55749466 transcription elongation factor A (SII)-like 8 [Homo sapiens] Length = 117 Score = 56.2 bits (134), Expect = 2e-08 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 73 EGEGKPQGEGKPASQAKPESQPRAAE--KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130 E EGKPQ K E P+ AE +P+E+ V ++A+ G + + +ED Sbjct: 7 ENEGKPQNMPKAEEDRPLEDVPQEAEGNPQPSEEGVSQEAEGNPRGGPNQPGQGFKEDTP 66 Query: 131 ERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFHWMQR 167 RHL EEM+R ++ R +EE+R+ + K HW QR Sbjct: 67 VRHLDPEEMIRGVDELERLREEIRRVRNKFVMMHWKQR 104 >gi|23503247 transcription elongation factor A (SII)-like 8 [Homo sapiens] Length = 117 Score = 56.2 bits (134), Expect = 2e-08 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 73 EGEGKPQGEGKPASQAKPESQPRAAE--KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130 E EGKPQ K E P+ AE +P+E+ V ++A+ G + + +ED Sbjct: 7 ENEGKPQNMPKAEEDRPLEDVPQEAEGNPQPSEEGVSQEAEGNPRGGPNQPGQGFKEDTP 66 Query: 131 ERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFHWMQR 167 RHL EEM+R ++ R +EE+R+ + K HW QR Sbjct: 67 VRHLDPEEMIRGVDELERLREEIRRVRNKFVMMHWKQR 104 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 55.5 bits (132), Expect = 3e-08 Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 5/154 (3%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 +E P + E E+EG E E + + +S+ E D EG+ + E + + E +E Q Sbjct: 2116 IEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQP 2175 Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQP--RAAEKRPAEDYV-PRKAKRKTDRG 117 E EG + + +EGE +P+ EG A +A+ E+QP E AE+ P +T Sbjct: 2176 ELEGVEAPE--AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEA 2233 Query: 118 TDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQE 151 ++ +S+ + Q S ++ G A E Sbjct: 2234 EGEAQPESEGETQGEKKGSPQVSLGDGQSEEASE 2267 Score = 50.4 bits (119), Expect = 1e-06 Identities = 40/139 (28%), Positives = 71/139 (51%), Gaps = 16/139 (11%) Query: 13 ENEGKPEDEV------EPDDEGKSDEEEKPDVEGKT-ECEGKREDEGE----PGDEGQLE 61 E + +PE EV E + + +S++ E +VE +T E EG+ + E E P EG+++ Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ 2010 Query: 62 DEGSQEKQGRSEG-EGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 E +E Q S+G E +P+ EG+ A + + E+Q + +P D V + + + Sbjct: 2011 -EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAP---EAEEEAQE 2066 Query: 121 SPKDSQEDLQERHLSSEEM 139 + + QE E H SE++ Sbjct: 2067 AEGEVQEAEGEAHPESEDV 2085 Score = 49.7 bits (117), Expect = 2e-06 Identities = 30/96 (31%), Positives = 53/96 (55%), Gaps = 11/96 (11%) Query: 9 EGNLENEGKPEDEVEPDDEG-----KSDEEEKPDVEG---KTECEGKREDEGEPGDEGQL 60 EG ++ + E+E +P+ +G KS+ EE +VEG KTE + + E +G E + Sbjct: 2006 EGEMQ---EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEE 2062 Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRA 96 E + ++ + +EGE P+ E A +A+ E+QP + Sbjct: 2063 EAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPES 2098 Score = 49.3 bits (116), Expect = 2e-06 Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 34/164 (20%) Query: 1 MEKPYNKNEGNLENEG----KPEDEVEPDDEG----KSDEEEKPDVEGKTECEGKREDEG 52 +E P + E E+E + E EV+P+ EG ++++E +P+ E E + EDE Sbjct: 1874 VEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEP 1933 Query: 53 EP-GDEGQLEDEGSQEKQGRS------------EGEGKPQGEGKPASQAKPESQPRAAEK 99 E G E Q +E +QE +G++ E E +P+ E A + + E+Q E Sbjct: 1934 ESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEA 1993 Query: 100 RPAEDYV------------PRKAKRKTDRGTDDSPKDSQEDLQE 131 +P + V +A+ ++D G + PK E+ QE Sbjct: 1994 QPESEDVEAPEAEGEMQEAEEEAQPESD-GVEAQPKSEGEEAQE 2036 Score = 48.5 bits (114), Expect = 4e-06 Identities = 48/195 (24%), Positives = 82/195 (42%), Gaps = 45/195 (23%) Query: 1 MEKPYNKNEGNLENEG--KPE-----DEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE 53 +E P + E E+EG PE E E + + +S++ E P+ EG+ + E + + E Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPE 1894 Query: 54 PGDEGQLEDEGSQ----EKQGR----------SEGEGKPQGEGKPASQAKPESQPRAAEK 99 E Q E EG++ EK+ + +EGE +P+ EG A +A+ +Q + Sbjct: 1895 AEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQT 1954 Query: 100 RPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKM 159 +P + + +SQE + EE E DV + E+ ++ Sbjct: 1955 QPESEVI-----------------ESQE-------AEEEAQPESEDVEALEVEVETQEAE 1990 Query: 160 GGFHWMQRDVQDPFA 174 G DV+ P A Sbjct: 1991 GEAQPESEDVEAPEA 2005 Score = 48.5 bits (114), Expect = 4e-06 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 14/143 (9%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 +E K EG+ + E + E ++E + E E + EG+ E + D E E Q Sbjct: 2037 VEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQP 2096 Query: 61 EDEG---------SQEKQG----RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVP 107 E EG +Q+ +G +EGE +P+ EG A +A+ E+QP +E A+D Sbjct: 2097 ESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPE-SEGVEAQDAEG 2155 Query: 108 RKAKRKTDRGTDDSPKDSQEDLQ 130 ++ +++Q +L+ Sbjct: 2156 EAQPESEGIEAQEAEEEAQPELE 2178 Score = 41.2 bits (95), Expect = 6e-04 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 13/123 (10%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEG----KTECEGKREDEG--EPGDEGQLEDEGSQ 66 E EG+ + E E + +++ E +P++EG + E E + E EG P EG+ + E Sbjct: 2184 EAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEG 2243 Query: 67 EKQGRSEGEGKPQ---GEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123 E QG E +G PQ G+G+ S+ ES E RP P G+ P Sbjct: 2244 ETQG--EKKGSPQVSLGDGQ--SEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPS 2299 Query: 124 DSQ 126 S+ Sbjct: 2300 SSR 2302 Score = 40.4 bits (93), Expect = 0.001 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 11/96 (11%) Query: 8 NEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQE 67 +E NL+ E + +P ++ E P+ EG E +P EG E + Sbjct: 1810 HEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEG----------EAQPESEGVEAPEAEGD 1859 Query: 68 KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103 Q +EGE +P+ E A +A+ E+QP + + E Sbjct: 1860 AQ-EAEGEAQPESEDVEAPEAEGEAQPESEDVETPE 1894 Score = 38.5 bits (88), Expect = 0.004 Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 14/141 (9%) Query: 7 KNEGNLENEG-KPEDEVEPDDEGKSDEE------EKPDVEGKTECEGKREDEGEPGDEGQ 59 K E L+ EG + E+ E + EG+ +EE E+ EG E EG + +E + G EG Sbjct: 1326 KTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQE-EGVQLEEVKEGPEGG 1384 Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 119 L+ E +E G E EG P+ EG Q E+ + +D V + + + Sbjct: 1385 LQGEALEE--GLKE-EGLPE-EGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAE 1440 Query: 120 DSPKDSQEDLQE--RHLSSEE 138 P + E+ E HLS + Sbjct: 1441 PCPAEGTEEPTEPPSHLSETD 1461 Score = 37.4 bits (85), Expect = 0.009 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 3/94 (3%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69 G E EG E E + G + +++G+ G ++ G EG E E Q Sbjct: 1788 GEAEQEG--EGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQ 1845 Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103 SEG P+ EG A +A+ E+QP + + E Sbjct: 1846 PESEGVEAPEAEG-DAQEAEGEAQPESEDVEAPE 1878 Score = 36.2 bits (82), Expect = 0.019 Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 6/112 (5%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60 +E P + E E EG E E + + + + E P+ EG+ + E + E +GE Q+ Sbjct: 2196 IEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQV 2255 Query: 61 E-DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 111 +G E+ S P E +P P +RP P ++ Sbjct: 2256 SLGDGQSEEASES---SSPVPEDRPTPPPSPGGD--TPHQRPGSQTGPSSSR 2302 Score = 35.8 bits (81), Expect = 0.025 Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 11/79 (13%) Query: 13 ENEGKPEDEVEPDD----EGKSDEEEKPDVEGKTECEGKREDEG------EPGDEGQLED 62 E EG E+ V+ ++ EG +E + + +TE EG++E+E E G EG L++ Sbjct: 1311 EGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEG-LQE 1369 Query: 63 EGSQEKQGRSEGEGKPQGE 81 EG Q ++ + EG QGE Sbjct: 1370 EGVQLEEVKEGPEGGLQGE 1388 Score = 35.0 bits (79), Expect = 0.043 Identities = 39/132 (29%), Positives = 55/132 (41%), Gaps = 17/132 (12%) Query: 13 ENEGKPEDEVEPDDEGKSDE---------EEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63 EN + E ++E EG E EE EG E + E+ E EGQ E+E Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEE 1353 Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAK--PES--QPRAAEKRPAEDYVPRKAK---RKTDR 116 E+ + GEG Q EG + K PE Q A E+ E+ +P + ++ Sbjct: 1354 AQLEEIEETGGEGL-QEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSE 1412 Query: 117 GTDDSPKDSQED 128 + K SQED Sbjct: 1413 ASSPDGKGSQED 1424 Score = 32.3 bits (72), Expect = 0.28 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 6/102 (5%) Query: 46 GKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKP------ASQAKPESQPRAAEK 99 G R E +PGD+ LE G + G+ EG P + +P +S P+S + Sbjct: 986 GLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQG 1045 Query: 100 RPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMR 141 E A+ DR + S L R +S ++MR Sbjct: 1046 AAPEGVSEAPAEAGADREAPAGCRVSLRALPGRVSASTQIMR 1087 Score = 29.3 bits (64), Expect = 2.3 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 12/85 (14%) Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEG--------QLE----DEGSQ 66 EDE E D E + + T E + +E + G EG QLE +EG Q Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQ 1332 Query: 67 EKQGRSEGEGKPQGEGKPASQAKPE 91 E+ + E + +GEG+ +A+ E Sbjct: 1333 EEGVQLEETKETEGEGQQEEEAQLE 1357 Score = 28.9 bits (63), Expect = 3.0 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 6/83 (7%) Query: 20 DEVEPDDEGKSDEEEKPDVE--GKTECEGKREDE-GEPGDEGQLEDEGSQEKQ--GRSEG 74 D + + EGK+ E G+ E EG+ E GE G +G ++ Q + G + Sbjct: 1766 DAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825 Query: 75 EGKPQG-EGKPASQAKPESQPRA 96 G+ G EG A +A+ E+QP + Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPES 1848 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 54.3 bits (129), Expect = 7e-08 Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 20/147 (13%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEG-------KREDEGEPGDEGQ 59 KNE + E + + E + GK D++EK + +GK + G K +++G+ G++G+ Sbjct: 124 KNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGK 183 Query: 60 LEDEGSQEK-------QGRSE-GEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 111 E +EK + R E G+GK +GK K + + ED R+ Sbjct: 184 GNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK-----EGKDVKVKEDEKEREDG 238 Query: 112 RKTDRGTDDSPKDSQEDLQERHLSSEE 138 ++ + G ++ +EDL+E EE Sbjct: 239 KEDEGGNEEEAGKEKEDLKEEEEGKEE 265 Score = 43.9 bits (102), Expect = 9e-05 Identities = 37/158 (23%), Positives = 72/158 (45%), Gaps = 13/158 (8%) Query: 9 EGNLEN---EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK--REDEGEPGDEGQLEDE 63 E N+E+ +G + E + +E++K D E + E +G+ +ED+ E G+E + Sbjct: 102 EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEE-----D 156 Query: 64 GSQEKQGRSEGE-GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSP 122 G ++K G +GE K + +GK K + + ++ RK D Sbjct: 157 GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216 Query: 123 KDSQEDLQERHLSSEEMMRECG--DVSRAQEELRKKQK 158 K +++ ++ + +E RE G D +EE K+++ Sbjct: 217 KGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKE 254 Score = 43.1 bits (100), Expect = 2e-04 Identities = 23/105 (21%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Query: 2 EKPYNKNEGNLENEGKP--EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQ 59 E K +G +GK ED E ++ K +E+ K +GK +GK + + + G + + Sbjct: 168 EDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVK 227 Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104 ++++ + + G+ + G + GK K E + + ++ +D Sbjct: 228 VKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272 Score = 41.6 bits (96), Expect = 5e-04 Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 17/165 (10%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKRED----EGEPGD 56 +E+ YN+N N G+ + P E + E ++ ++E TE G++++ E + + Sbjct: 72 VEEDYNENAKN----GEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEE 127 Query: 57 EGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 116 E Q EDE Q ++ G+ +G+ + + + + ED K + + Sbjct: 128 EDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED----GKKGEDGK 183 Query: 117 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGG 161 G + K+ ED +E EE +E GD ++ K K G Sbjct: 184 GNGEDGKEKGEDEKE-----EEDRKETGDGKENEDGKEKGDKKEG 223 Score = 40.4 bits (93), Expect = 0.001 Identities = 34/91 (37%), Positives = 46/91 (50%), Gaps = 7/91 (7%) Query: 7 KNEGNLENEGKPED---EVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63 K E E E + E + D + K D++E DV+ K E E +RED E DEG E+E Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK-EDEKEREDGKE--DEGGNEEE 248 Query: 64 GSQEKQG-RSEGEGKPQGEGKPASQAKPESQ 93 +EK+ + E EGK + E K K E Q Sbjct: 249 AGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279 Score = 35.4 bits (80), Expect = 0.033 Identities = 27/71 (38%), Positives = 40/71 (56%), Gaps = 7/71 (9%) Query: 2 EKPYNKNEGNLENEGKP----EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDE 57 E K +G+ + EGK EDE E +D GK DE + GK + + K E+EG+ DE Sbjct: 210 ENEDGKEKGD-KKEGKDVKVKEDEKERED-GKEDEGGNEEEAGKEKEDLKEEEEGKEEDE 267 Query: 58 GQLEDEGSQEK 68 + ED+G +E+ Sbjct: 268 IK-EDDGKKEE 277 Score = 30.4 bits (67), Expect = 1.0 Identities = 23/54 (42%), Positives = 32/54 (59%), Gaps = 6/54 (11%) Query: 15 EGKPEDEVEPDDEGKSDEE---EKPDVEGKTECEGKREDEGEPGDEGQLEDEGS 65 E + E E +DEG ++EE EK D+ K E EGK EDE + D+G+ E+ S Sbjct: 230 EDEKEREDGKEDEGGNEEEAGKEKEDL--KEEEEGKEEDEIKE-DDGKKEEPQS 280 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 53.5 bits (127), Expect = 1e-07 Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 5/145 (3%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72 E++ EDE + +DE + ++E +P EDE + DE +D+ +E Sbjct: 149 EDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEE 208 Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQER 132 E +GK A++ P AE ED D DD D ++D +E Sbjct: 209 EAMETTPAKGKKAAKVVPVKAKNVAED---EDEEEDDEDEDDDDDEDDEDDDDEDDEEEE 265 Query: 133 HLSSEEMMRECGDVSRAQEELRKKQ 157 EE ++E + ++E+ K++ Sbjct: 266 EEEEEEPVKEA--PGKRKKEMAKQK 288 Score = 37.0 bits (84), Expect = 0.011 Identities = 25/123 (20%), Positives = 53/123 (43%), Gaps = 21/123 (17%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKR----------------EDEGEPGD 56 E+E +DE + DD+ +++ + + T +GK+ ++E + D Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244 Query: 57 EGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 116 E +DE ++ + E + + E +P +A P +K A+ +AK++ Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEA-----PGKRKKEMAKQKAAPEAKKQKVE 299 Query: 117 GTD 119 GT+ Sbjct: 300 GTE 302 Score = 34.7 bits (78), Expect = 0.056 Identities = 24/125 (19%), Positives = 52/125 (41%), Gaps = 18/125 (14%) Query: 4 PYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKT------------------ECE 45 P +++E + ++E +D+ + +D+ + + E +GK E + Sbjct: 182 PASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEED 241 Query: 46 GKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDY 105 + ED+ + D+ +DE +E++ E E + GK + + A+K+ E Sbjct: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301 Query: 106 VPRKA 110 P A Sbjct: 302 EPTTA 306 Score = 30.0 bits (66), Expect = 1.4 Identities = 16/50 (32%), Positives = 30/50 (60%), Gaps = 4/50 (8%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE 51 E+ +++E + ++E +D+ E D+E + +EEE+P E GKR+ E Sbjct: 238 EEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEP----VKEAPGKRKKE 283 >gi|21361639 DIPB protein [Homo sapiens] Length = 344 Score = 50.1 bits (118), Expect = 1e-06 Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 6/162 (3%) Query: 4 PYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63 P EG + E + + E E + E ++ EE + + E ++E E + E+E E + + E++ Sbjct: 69 PPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEED 128 Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK-TDRGTDDSP 122 +E + E E + + + S+A+ E++ + E R AKRK D G D S Sbjct: 129 SEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLST 188 Query: 123 KDSQEDLQ----ERHLSSEEMMRECGDVSRAQEELRKKQKMG 160 QED Q + + + A EELR K G Sbjct: 189 Y-CQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGG 229 Score = 42.7 bits (99), Expect = 2e-04 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Query: 2 EKPYNKNEGNLENEGKPEDEV--EPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQ 59 E+ ++ E E E + E+E E D+E + D EE+ + E ++E E ++EGE EG+ Sbjct: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156 Query: 60 LEDEGSQEKQGRSEGE 75 E E + + E E Sbjct: 157 TEAESEFDPEIEMEAE 172 Score = 33.1 bits (74), Expect = 0.16 Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 5/136 (3%) Query: 20 DEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLED--EGSQEKQGRSEGEGK 77 DE EPD+ ++E + G C E + L + GSQ ++GEG Sbjct: 19 DECEPDEAPGAEEVCREC--GFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGA 76 Query: 78 PQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT-DRGTDDSPKDSQEDLQERHLSS 136 + E + + + E + A E+ +E+ + + +T + D+S ++S+ED +E Sbjct: 77 GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136 Query: 137 EEMMRECGDVSRAQEE 152 +E E + + E Sbjct: 137 QESEAEEDNQEEGESE 152 Score = 28.1 bits (61), Expect = 5.2 Identities = 13/48 (27%), Positives = 26/48 (54%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKRE 49 E+ ++ E E + + E E E + E +++ E P++E + E KR+ Sbjct: 131 EEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 50.1 bits (118), Expect = 1e-06 Identities = 32/138 (23%), Positives = 68/138 (49%), Gaps = 10/138 (7%) Query: 9 EGNLENEGKPED----EVEPDDEGKSDEEEK-PDVEGKTECEGKREDEGEPGDEGQLEDE 63 EG EG+ E+ E +P+ EG+++ + K + E + E EGK ++EGE DEG++ E Sbjct: 760 EGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGE--DEGEIHAE 817 Query: 64 GSQEKQGRSEGEGK---PQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 + K E E + + G+ + K ++ +E+ + +++ + ++ Sbjct: 818 DGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEE 877 Query: 121 SPKDSQEDLQERHLSSEE 138 ++ +E+ +E +EE Sbjct: 878 QEEEEEEEEEEEEKGNEE 895 Score = 43.9 bits (102), Expect = 9e-05 Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 41/183 (22%) Query: 15 EGKPEDEVE-----------PDDEGKSDEEEKPD-VEGKTECEGKRE---DEGEPGDEGQ 59 E KPE+E P + K D++E P E E E E +EGE EG+ Sbjct: 709 ESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGE 768 Query: 60 LEDEGSQEKQGRSEGEGKPQG-----------EGKPASQAKPESQPRA------------ 96 E++ E Q EGE + QG EGK ++ + E + A Sbjct: 769 TEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGET 828 Query: 97 -AEKRPAEDYVPRKAKRK--TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEEL 153 +++ AE++ K K D G D +E+ +E EE E + +EE Sbjct: 829 ESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEE 888 Query: 154 RKK 156 +K Sbjct: 889 EEK 891 Score = 43.5 bits (101), Expect = 1e-04 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 20/112 (17%) Query: 6 NKNEGNLENEGKPEDEVEPDD---EGKSDEEEKPDVEGKTECEGKREDEG---------- 52 N+ EG +NEG+ E E+ +D +G E E ++ + E K +++G Sbjct: 798 NEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGG 857 Query: 53 -------EPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97 E ++ + E+E QE++ E E + +G +P S PE++ + A Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQA 909 Score = 42.0 bits (97), Expect = 3e-04 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 18/124 (14%) Query: 7 KNEGNLENEGKPED-EVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLED--- 62 + EG E +GK E+ E E + EGK D EG+ E E ED G+EG+ E Sbjct: 780 EGEGETETQGKGEECEDENEAEGKGDN------EGEDEGEIHAEDGEMKGNEGETESQEL 833 Query: 63 ------EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 116 E +++G +G G G+ + + + E + E+ E+ + + + ++ Sbjct: 834 SAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE--EEEEEEEEEK 891 Query: 117 GTDD 120 G ++ Sbjct: 892 GNEE 895 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 49.3 bits (116), Expect = 2e-06 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 8/145 (5%) Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE-PGDEGQLEDEGSQEKQGRSEGEGK 77 E E+E EGK + E + E + + KRE E E + G+ E +G ++K+ R + + Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101 Query: 78 PQGEGKPASQ----AKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERH 133 + E K + K E + R + ++ ++ +++ +R + K+ +E +ER Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER- 160 Query: 134 LSSEEMMRECGDVSRAQEELRKKQK 158 E RE V +EE ++K++ Sbjct: 161 --KERKKRERKQVGEKEEERKEKER 183 Score = 48.5 bits (114), Expect = 4e-06 Identities = 36/165 (21%), Positives = 78/165 (47%), Gaps = 15/165 (9%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSD-EEEKPDVEGKTECEG------------KREDEGE 53 + EG E E + + E ++ K + E+E+ GK E +G +RE E + Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK 107 Query: 54 PGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 113 G+E + + ++++GR+ EGK + + + + + + R E+R E RK ++K Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER--ERKERKK 165 Query: 114 TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158 +R ++ +++ + + E R+ R ++E R+++K Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210 Score = 47.0 bits (110), Expect = 1e-05 Identities = 37/151 (24%), Positives = 74/151 (49%), Gaps = 4/151 (2%) Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68 E E E + E + E + E K + E+ + + E E KRE G+ +G+ + E + K Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRE-RGKKEKKGERKKEERERK 98 Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128 + R E E K +GE K + K E + R + ++ ++ +++ +R + K+ +E Sbjct: 99 KRRREKENK-EGEEKE-KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156 Query: 129 LQERHLSSEEMMRECGDVSRAQEEL-RKKQK 158 +ER + ++ G+ ++E RK++K Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERK 187 Score = 45.4 bits (106), Expect = 3e-05 Identities = 36/134 (26%), Positives = 63/134 (47%), Gaps = 5/134 (3%) Query: 28 GKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG---RSEGEGKPQGEGKP 84 G E + + E +T EGK+E E E E + ++ +E++ R G+ + +GE K Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92 Query: 85 ASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECG 144 + + + + R E + E+ RK K K +RG S + + + +E E RE Sbjct: 93 EERERKKRR-REKENKEGEEKEKRKKKEKKERGR-TSKEGKERERKEERKREERKERERK 150 Query: 145 DVSRAQEELRKKQK 158 R +E RK++K Sbjct: 151 KEEREKERERKERK 164 Score = 43.1 bits (100), Expect = 2e-04 Identities = 34/173 (19%), Positives = 79/173 (45%), Gaps = 18/173 (10%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE------PG 55 EK + G E +G+ + E + E K EK + EG+ + + K++++ E G Sbjct: 74 EKERKRERGKKEKKGERKKE---ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130 Query: 56 DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTD 115 E + ++E +E++ E + + + + + + K + + EK RK ++K + Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190 Query: 116 RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRD 168 R + K+ + +ER +E ++ +E +++QK +W +++ Sbjct: 191 RNRKERKKERER--KERRERKKERKKK-------EERKKERQKDRQTNWREKE 234 Score = 40.8 bits (94), Expect = 8e-04 Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 11/157 (7%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK--------REDEGEPGDEG 58 K E + + ++ E +++ K ++EK + G+T EGK + +E + + Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKE-RGRTSKEGKERERKEERKREERKERERK 150 Query: 59 QLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT 118 + E E +E++ R + E K GE + + K + + E+ E R+ K + +R Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210 Query: 119 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK 155 + K+ ++ +ER + RE R ++E +K Sbjct: 211 ERKKKEERK--KERQKDRQTNWREKERGKRERKERKK 245 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 48.9 bits (115), Expect = 3e-06 Identities = 28/91 (30%), Positives = 49/91 (53%), Gaps = 5/91 (5%) Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGS 65 +K +G L +E + E+E E ++E + DEEE+ + E + E E + E+E E +E + E+E + Sbjct: 249 SKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308 Query: 66 -----QEKQGRSEGEGKPQGEGKPASQAKPE 91 QE + + P+ G + KPE Sbjct: 309 PDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339 Score = 40.0 bits (92), Expect = 0.001 Identities = 36/190 (18%), Positives = 81/190 (42%), Gaps = 11/190 (5%) Query: 8 NEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQE 67 +E + + +G E E ++E + +EEE+ D E + E E + E+E E +E + E+E +E Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304 Query: 68 KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQE 127 ++ + + A +A P + +P + + ++D D+ + Sbjct: 305 EEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVI---VEVRSDDDKDEDTHSRKS 361 Query: 128 DLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGG 187 + + + M R G++ ++ + K + R V +P P ++ G+ Sbjct: 362 TVTDESEMQDMMTR--GNLGLLEQAIALKAE------QVRTVCEPGCPPAEQSQLGLGEP 413 Query: 188 GRGQRGLHDI 197 G+ + L + Sbjct: 414 GKAAKPLDTV 423 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 48.9 bits (115), Expect = 3e-06 Identities = 38/108 (35%), Positives = 50/108 (46%), Gaps = 16/108 (14%) Query: 7 KNEGNLENEGKPEDEVEP-----------DDEGKSDEEEKPDVEGKTECEGKREDEGEPG 55 K E E E +PE E E E K +E EK + EG+ E E EDEG Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE--EEDEGAKS 545 Query: 56 DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103 D+ + EG EK+G SE E Q EG+ ++A+ E EK+ E Sbjct: 546 DQAE---EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 590 Score = 45.4 bits (106), Expect = 3e-05 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 21/120 (17%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ--G 70 E EG+ E+E EG+ +EEE E EG + D+ E EG E EGS EK+ Sbjct: 522 EEEGEKEEE-----EGQEEEEE--------EDEGAKSDQAE---EGGSEKEGSSEKEEGE 565 Query: 71 RSEGEGKPQGEGKPASQAKPES--QPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128 + EGE + + EG+ A +AK E + ++ E E+ V K ++ PK E+ Sbjct: 566 QEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 624 Score = 45.1 bits (105), Expect = 4e-05 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 7/129 (5%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEK--PDVEGKTECEGKREDEGEPGDEGQLED-E 63 + EG E E E+E E D+ KSD+ E+ + EG +E E ++EGE E + E+ E Sbjct: 522 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 581 Query: 64 GSQEK--QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED--YVPRKAKRKTDRGTD 119 +EK + +SE + A KPE K P E+ P ++G Sbjct: 582 AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 641 Query: 120 DSPKDSQED 128 PK E+ Sbjct: 642 PVPKSPVEE 650 Score = 32.0 bits (71), Expect = 0.36 Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 19/118 (16%) Query: 21 EVEPDDEGK----SDEEEKPDVEGKTECEG--------KRED---EGEPGDEGQLEDEGS 65 E E +EGK E+EK EG +E EG ++ED GE + ++E E Sbjct: 758 EKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 817 Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123 ++ GR E +G P + + +K + V + ++ T G D + K Sbjct: 818 EKGSGREEEKGVVTN----GLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATK 871 Score = 28.9 bits (63), Expect = 3.0 Identities = 21/66 (31%), Positives = 29/66 (43%) Query: 11 NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG 70 N E EGK E E E ++G EEEK V + E +G E ++ + EK Sbjct: 803 NGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 862 Query: 71 RSEGEG 76 G+G Sbjct: 863 SEGGDG 868 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 48.9 bits (115), Expect = 3e-06 Identities = 38/108 (35%), Positives = 50/108 (46%), Gaps = 16/108 (14%) Query: 7 KNEGNLENEGKPEDEVEP-----------DDEGKSDEEEKPDVEGKTECEGKREDEGEPG 55 K E E E +PE E E E K +E EK + EG+ E E EDEG Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE--EEDEGAKS 169 Query: 56 DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103 D+ + EG EK+G SE E Q EG+ ++A+ E EK+ E Sbjct: 170 DQAE---EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 214 Score = 45.4 bits (106), Expect = 3e-05 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 21/120 (17%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ--G 70 E EG+ E+E EG+ +EEE E EG + D+ E EG E EGS EK+ Sbjct: 146 EEEGEKEEE-----EGQEEEEE--------EDEGAKSDQAE---EGGSEKEGSSEKEEGE 189 Query: 71 RSEGEGKPQGEGKPASQAKPES--QPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128 + EGE + + EG+ A +AK E + ++ E E+ V K ++ PK E+ Sbjct: 190 QEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 248 Score = 45.1 bits (105), Expect = 4e-05 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 7/129 (5%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEK--PDVEGKTECEGKREDEGEPGDEGQLED-E 63 + EG E E E+E E D+ KSD+ E+ + EG +E E ++EGE E + E+ E Sbjct: 146 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 205 Query: 64 GSQEK--QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED--YVPRKAKRKTDRGTD 119 +EK + +SE + A KPE K P E+ P ++G Sbjct: 206 AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 265 Query: 120 DSPKDSQED 128 PK E+ Sbjct: 266 PVPKSPVEE 274 Score = 32.0 bits (71), Expect = 0.36 Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 19/118 (16%) Query: 21 EVEPDDEGK----SDEEEKPDVEGKTECEG--------KRED---EGEPGDEGQLEDEGS 65 E E +EGK E+EK EG +E EG ++ED GE + ++E E Sbjct: 382 EKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 441 Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123 ++ GR E +G P + + +K + V + ++ T G D + K Sbjct: 442 EKGSGREEEKGVVTN----GLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATK 495 Score = 28.9 bits (63), Expect = 3.0 Identities = 21/66 (31%), Positives = 29/66 (43%) Query: 11 NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG 70 N E EGK E E E ++G EEEK V + E +G E ++ + EK Sbjct: 427 NGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 486 Query: 71 RSEGEG 76 G+G Sbjct: 487 SEGGDG 492 >gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog [Homo sapiens] Length = 666 Score = 47.8 bits (112), Expect = 6e-06 Identities = 46/205 (22%), Positives = 80/205 (39%), Gaps = 26/205 (12%) Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEE-----EKPDVEGKTECEGKREDEGEPG-DEGQ 59 +++EG+ + G E E ++ SD+E +K D + + ++E G DE + Sbjct: 116 DEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDK 175 Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPA-------------EDYV 106 L++ EK ++ E +PQ Q E + + ++RP E+ Sbjct: 176 LQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQP 235 Query: 107 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRA----QEELRKKQKMGGF 162 + K D+ P+ S E + RH EE + +R E LR K+K Sbjct: 236 QLSDEEKMQNSDDERPQASDE--EHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIA 293 Query: 163 HWMQRDVQDPFAPRGQRGVRGVRGG 187 + D D P+ G + GG Sbjct: 294 SDSEAD-SDTEVPKDNSGTMDLFGG 317 Score = 42.0 bits (97), Expect = 3e-04 Identities = 37/171 (21%), Positives = 72/171 (42%), Gaps = 31/171 (18%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGK---SDEEEKPDVEGKTECEGKREDEGEPGDEG 58 E+ +E L+N DD+ K +D+EE+P + + E++ DE Sbjct: 166 ERAQGSDEDKLQNS---------DDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDER 216 Query: 59 QLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA--EKRPAEDYVPRKAKRKTDR 116 + + EKQ S+ E +PQ + Q + +P+A+ E R ++D + K ++ R Sbjct: 217 PVASDNDDEKQ-NSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESAR 275 Query: 117 GTD----------------DSPKDSQEDLQERHLSSEEMMRECGDVSRAQE 151 G+D DS DS ++ + + + ++ D+S + Sbjct: 276 GSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSD 326 Score = 38.1 bits (87), Expect = 0.005 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 6/127 (4%) Query: 14 NEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG-RS 72 ++ E E + D G + ++ + + G D+ E GD GQ ++E G S Sbjct: 10 SDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQ---PSNKELFGDDS 66 Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK--TDRGTDDSPKDSQEDLQ 130 E EG G + +++ A+E+ ED P + ++ DD + + D Sbjct: 67 EDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGG 126 Query: 131 ERHLSSE 137 H +E Sbjct: 127 SHHSEAE 133 Score = 36.6 bits (83), Expect = 0.015 Identities = 28/139 (20%), Positives = 54/139 (38%), Gaps = 14/139 (10%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 E+ N++E + ++ + D + D S+ + EG G E E ++ + Sbjct: 82 ERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSD 141 Query: 62 DE--GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 119 DE G ++K +S+ E + + +Q E D + + + TD Sbjct: 142 DEKWGREDKSDQSDDEKIQNSDDEERAQGSDE------------DKLQNSDDDEKMQNTD 189 Query: 120 DSPKDSQEDLQERHLSSEE 138 D + D + + LS EE Sbjct: 190 DEERPQLSDDERQQLSEEE 208 Score = 33.1 bits (74), Expect = 0.16 Identities = 37/176 (21%), Positives = 57/176 (32%), Gaps = 33/176 (18%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE---------- 51 E+P +E ++N + ++ SD+EE+ D + ++ EDE Sbjct: 233 EQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAI 292 Query: 52 ----------GEPGDEGQLED--EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEK 99 P D D G+ + S+GE KP G+P + + E Sbjct: 293 ASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEP 352 Query: 100 RPAEDYVPRKAKRKTDRGTD-----------DSPKDSQEDLQERHLSSEEMMRECG 144 P K TD G D P+ E EEM+ E G Sbjct: 353 IPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEG 408 Score = 30.0 bits (66), Expect = 1.4 Identities = 31/152 (20%), Positives = 58/152 (38%), Gaps = 11/152 (7%) Query: 30 SDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGE-GKPASQA 88 +D E+ + +E E K D G D Q E+ S SE + +G+ G+P+++ Sbjct: 2 ADMEDLFGSDADSEAERKDSDSGSDSDSDQ-ENAASGSNASGSESDQDERGDSGQPSNKE 60 Query: 89 --KPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSE-------EM 139 +S+ A D ++ +++ +D+ ++H SE E Sbjct: 61 LFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEG 120 Query: 140 MRECGDVSRAQEELRKKQKMGGFHWMQRDVQD 171 R G ++ E +K W + D D Sbjct: 121 HRSDGGSHHSEAEGSEKAHSDDEKWGREDKSD 152 >gi|55743140 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 47.4 bits (111), Expect = 8e-06 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125 Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++ Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56 Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164 +ED+ RHLS+E+M RE V E R + K+ W Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92 Score = 38.1 bits (87), Expect = 0.005 Identities = 19/41 (46%), Positives = 24/41 (58%) Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43 K K EG ENE +P+ E EP E K +EEEK + E K + Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42 Score = 36.6 bits (83), Expect = 0.015 Identities = 18/33 (54%), Positives = 21/33 (63%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47 EGKPE+E EP E + EEKP+ E K E E K Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40 >gi|55743147 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 47.4 bits (111), Expect = 8e-06 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125 Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++ Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56 Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164 +ED+ RHLS+E+M RE V E R + K+ W Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92 Score = 38.1 bits (87), Expect = 0.005 Identities = 19/41 (46%), Positives = 24/41 (58%) Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43 K K EG ENE +P+ E EP E K +EEEK + E K + Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42 Score = 36.6 bits (83), Expect = 0.015 Identities = 18/33 (54%), Positives = 21/33 (63%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47 EGKPE+E EP E + EEKP+ E K E E K Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40 >gi|10047100 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 47.4 bits (111), Expect = 8e-06 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125 Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++ Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56 Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164 +ED+ RHLS+E+M RE V E R + K+ W Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92 Score = 38.1 bits (87), Expect = 0.005 Identities = 19/41 (46%), Positives = 24/41 (58%) Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43 K K EG ENE +P+ E EP E K +EEEK + E K + Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42 Score = 36.6 bits (83), Expect = 0.015 Identities = 18/33 (54%), Positives = 21/33 (63%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47 EGKPE+E EP E + EEKP+ E K E E K Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40 >gi|55743145 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 47.4 bits (111), Expect = 8e-06 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125 Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++ Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56 Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164 +ED+ RHLS+E+M RE V E R + K+ W Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92 Score = 38.1 bits (87), Expect = 0.005 Identities = 19/41 (46%), Positives = 24/41 (58%) Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43 K K EG ENE +P+ E EP E K +EEEK + E K + Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42 Score = 36.6 bits (83), Expect = 0.015 Identities = 18/33 (54%), Positives = 21/33 (63%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47 EGKPE+E EP E + EEKP+ E K E E K Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 47.0 bits (110), Expect = 1e-05 Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 16/192 (8%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEG 74 +G P P GK E+ KP + GK G+ D GE G +G+ D G+ ++GR Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGK---NGEPGDPGEDGRKGEKGDSGASGREGRDGP 1873 Query: 75 EGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHL 134 +G+ G Q P VP K DRG S K Q ER L Sbjct: 1874 KGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGS-KGEQGLPGERGL 1932 Query: 135 SSE--------EMMRECGDVSRAQEELRK--KQKMGGFHWMQRDVQDPFAPRGQRGVRGV 184 E ++ G + A E+ + + G F + + P G++G G Sbjct: 1933 RGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGK 1992 Query: 185 RG--GGRGQRGL 194 G G G+RGL Sbjct: 1993 EGPIGFPGERGL 2004 Score = 39.7 bits (91), Expect = 0.002 Identities = 52/196 (26%), Positives = 72/196 (36%), Gaps = 23/196 (11%) Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGE 75 G P + +P D G + G + G++ D G PG G + G + G E Sbjct: 1583 GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE 1642 Query: 76 GKPQGEGKPAS------QAKPESQPRAAEK----RPAED---YVPRKAKRKTDRGTDDSP 122 G P G P + P + EK P ED P + K DRG P Sbjct: 1643 GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP 1702 Query: 123 KDSQEDLQERHLSSEEMMRECGDV-SRAQEELRKKQKMGGFHWM--QRDVQDPFAPRGQR 179 R + + RE G+ R QE R + G +R ++ P G + Sbjct: 1703 GP-----PGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ 1757 Query: 180 GVRGVRG--GGRGQRG 193 G GVRG G +G RG Sbjct: 1758 GDPGVRGPAGEKGDRG 1773 Score = 39.7 bits (91), Expect = 0.002 Identities = 51/197 (25%), Positives = 73/197 (37%), Gaps = 26/197 (13%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69 G +EG P D P G+ P V G G++ D+G+PG++G+ GS + Sbjct: 1637 GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV---GEKGDQGDPGEDGRNGSPGSSGPK 1693 Query: 70 GRSEGEGKPQGEGK-----PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD--SP 122 G G P G+ P ++ K E R E P +RG + P Sbjct: 1694 GDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGP 1753 Query: 123 KDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVR 182 Q D R + E+ GD R L + + G + P P G G Sbjct: 1754 PGPQGDPGVRGPAGEK-----GD--RGPPGLDGRSGLDG----KPGAAGPSGPNGAAGKA 1802 Query: 183 GVRG-----GGRGQRGL 194 G G G RG++GL Sbjct: 1803 GDPGRDGLPGLRGEQGL 1819 Score = 38.9 bits (89), Expect = 0.003 Identities = 46/185 (24%), Positives = 68/185 (36%), Gaps = 17/185 (9%) Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGE 75 G+ D P +G+S + KP G + G G+PG +G G + +QG Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL---PGLRGEQGLPGPS 1823 Query: 76 GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLS 135 G P GKP KP + E P + P + RK ++G + D + Sbjct: 1824 GPPGLPGKPGEDGKPGLNGKNGE--PGD---PGEDGRKGEKGDSGASGREGRDGPKGERG 1878 Query: 136 SEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG--GGRGQRG 193 + ++ G Q G V P+G RG G +G G G+RG Sbjct: 1879 APGILGPQGPPGLPGPVGPPGQGFPG-------VPGGTGPKGDRGETGSKGEQGLPGERG 1931 Query: 194 LHDIP 198 L P Sbjct: 1932 LRGEP 1936 Score = 38.1 bits (87), Expect = 0.005 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 2/102 (1%) Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83 P G + E KP + G G + G PG+ G+ ++G + +QGR G P G Sbjct: 2027 PGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGP 2086 Query: 84 PASQAKPESQPRAAEKRPAEDYVP--RKAKRKTDRGTDDSPK 123 P S E P + AK + D PK Sbjct: 2087 PGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPK 2128 Score = 35.4 bits (80), Expect = 0.033 Identities = 47/180 (26%), Positives = 66/180 (36%), Gaps = 21/180 (11%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEG------QLEDEGSQEK 68 +G+P D + G + P G+ EG R G GD G + D G Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777 Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAAEKR--PAEDYVPRKAKRKTDRGTDDSPKDSQ 126 GRS +GKP G P AA K P D +P + G P Sbjct: 1778 DGRSGLDGKPGAAG-------PSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830 Query: 127 EDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG 186 + ++ E GD E+ RK +K G R+ +D P+G+RG G+ G Sbjct: 1831 KPGEDGKPGLNGKNGEPGDPG---EDGRKGEK-GDSGASGREGRD--GPKGERGAPGILG 1884 Score = 33.9 bits (76), Expect = 0.095 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 18 PEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGK 77 P+ V+ G S E+ P ++G G D+G GD G +G + + G +G Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151 Query: 78 PQGEGKPASQAKPESQP 94 P G+ A PE +P Sbjct: 2152 PGLPGE-RGMAGPEGKP 2167 Score = 33.9 bits (76), Expect = 0.095 Identities = 44/179 (24%), Positives = 66/179 (36%), Gaps = 20/179 (11%) Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83 P G + + G +G R D G+PGD+G + G + G G +G+ Sbjct: 2529 PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588 Query: 84 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMR-E 142 P + P P + P +D VP K D G + R L E ++ Sbjct: 2589 PGAAGIP-GDPGS----PGKDGVPGIRGEKGDVGF----------MGPRGLKGERGVKGA 2633 Query: 143 CG-DVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG--GGRGQRGLHDIP 198 CG D + + G + ++ +P P GQ G G G G +G RG P Sbjct: 2634 CGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVP-GQSGAPGKEGLIGPKGDRGFDGQP 2691 Score = 33.9 bits (76), Expect = 0.095 Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 7/98 (7%) Query: 26 DEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGE---G 82 D+G+ E P + G G G PG G + G + QG+ +GE P GE G Sbjct: 2696 DQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQ-KGERGPPGERVVG 2754 Query: 83 KPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 P P + PA PR K + DD Sbjct: 2755 APGVPGAPGERGEQGRPGPAG---PRGEKGEAALTEDD 2789 Score = 33.1 bits (74), Expect = 0.16 Identities = 29/111 (26%), Positives = 41/111 (36%), Gaps = 6/111 (5%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEG 74 +G+P P G P ++G G R D GE G G + G+ + EG Sbjct: 1304 DGRPGS---PGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEG 1360 Query: 75 EGKPQGEGKPASQAKPESQPRAAEKRP-AEDYVPRKAKR--KTDRGTDDSP 122 G P +G P P + + P +P A + K DRG P Sbjct: 1361 PGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPP 1411 Score = 32.7 bits (73), Expect = 0.21 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 6/95 (6%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69 G + G+ + E DEG + P G+ G G G++G D G + Sbjct: 1625 GPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRN 1684 Query: 70 GRSEGEGKPQGE-GKPASQAKP----ESQPRAAEK 99 G S G P+G+ G+P P ++ P A EK Sbjct: 1685 G-SPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREK 1718 Score = 32.0 bits (71), Expect = 0.36 Identities = 28/109 (25%), Positives = 39/109 (35%), Gaps = 5/109 (4%) Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68 +G ++G+ P G E +P V G++ GK G GD G G + Sbjct: 2637 DGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGD 2696 Query: 69 QGRSEGEGKPQGEGKPA-----SQAKPESQPRAAEKRPAEDYVPRKAKR 112 QG G P G P A P P + R E +K +R Sbjct: 2697 QGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGER 2745 Score = 31.6 bits (70), Expect = 0.47 Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 17/191 (8%) Query: 18 PEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGK 77 P E +G S E+ P EG G+R +G+ G D G Q G + GE Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRG------DPGPQGPPGLALGERG 2025 Query: 78 PQG----EGKPASQAKPESQPRAA----EKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDL 129 P G G+P P RA RP E + + ++G D P Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085 Query: 130 QERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG--G 187 + + E G ++ + G D Q P RG G++G RG G Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGD-QGPKGDRGVPGIKGDRGEPG 2144 Query: 188 GRGQRGLHDIP 198 RGQ G +P Sbjct: 2145 PRGQDGNPGLP 2155 Score = 31.6 bits (70), Expect = 0.47 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 9/57 (15%) Query: 26 DEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEG 82 D+G + P ++G D GEPG GQ + G ++G + EGKP +G Sbjct: 2124 DQGPKGDRGVPGIKG---------DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQG 2171 Score = 31.6 bits (70), Expect = 0.47 Identities = 19/61 (31%), Positives = 26/61 (42%) Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83 P + G + E KP ++G G G+PG G G QG S +G+P G Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGP 2214 Query: 84 P 84 P Sbjct: 2215 P 2215 Score = 31.2 bits (69), Expect = 0.61 Identities = 41/177 (23%), Positives = 60/177 (33%), Gaps = 19/177 (10%) Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE-----PGDEGQLEDEGSQEKQG 70 G E + P + G P +G GK+ ++G+ PG GQ G Q +G Sbjct: 1412 GPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRG 1471 Query: 71 RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDY-VPRKAKRKTDRGTDDSPKDSQEDL 129 G G P + + PA +P A R +G + P + Sbjct: 1472 PPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQ- 1530 Query: 130 QERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG 186 E G+ R + + G + DV P PRG GV+G RG Sbjct: 1531 -----------GEKGEPGRPGDPAVVGPAVAGPKGEKGDV-GPAGPRGATGVQGERG 1575 Score = 29.6 bits (65), Expect = 1.8 Identities = 42/166 (25%), Positives = 56/166 (33%), Gaps = 19/166 (11%) Query: 36 PDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPR 95 P V G G R + G+PG G+ G ++G G P G P S P + Sbjct: 2400 PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP---GPPGSVGPPGASGL 2456 Query: 96 AAEKRPAEDYVPRKAKRKTD---RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152 +K +P + + RG D P S E GDV A Sbjct: 2457 KGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSA--- 2513 Query: 153 LRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG-----GGRGQRG 193 + G + P PRG +G G RG G +G RG Sbjct: 2514 -----GLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRG 2554 Score = 29.3 bits (64), Expect = 2.3 Identities = 20/76 (26%), Positives = 27/76 (35%), Gaps = 1/76 (1%) Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEG 74 +G+P E P G + + G G +G PG GQ+ + G GR Sbjct: 2206 KGEP-GETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGA 2264 Query: 75 EGKPQGEGKPASQAKP 90 GK G P P Sbjct: 2265 SGKDGDRGSPGVPGSP 2280 Score = 28.5 bits (62), Expect = 4.0 Identities = 24/96 (25%), Positives = 34/96 (35%), Gaps = 4/96 (4%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL- 60 E+ + +G + G+ + P G P G G R +GEPG GQ+ Sbjct: 1297 ERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVI 1356 Query: 61 --EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQP 94 E G ++G G P G P P P Sbjct: 1357 GGEGPGLPGRKG-DPGPSGPPGPRGPLGDPGPRGPP 1391 Score = 28.5 bits (62), Expect = 4.0 Identities = 17/57 (29%), Positives = 23/57 (40%) Query: 14 NEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG 70 ++G D +P D+G E G G +G+PG G D GS K G Sbjct: 2549 DKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605 Score = 27.7 bits (60), Expect = 6.8 Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 26 DEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKP 84 + G + P G+ G+ + G+PG++GQ G + +G G G P G P Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG-DPGVGVPGSPGPP 2382 Score = 27.7 bits (60), Expect = 6.8 Identities = 17/58 (29%), Positives = 25/58 (43%), Gaps = 2/58 (3%) Query: 35 KPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEG--KPQGEGKPASQAKP 90 +P +G G R ++GE G G+ D G ++G +G G G P S P Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPP 2382 Score = 27.7 bits (60), Expect = 6.8 Identities = 22/99 (22%), Positives = 35/99 (35%), Gaps = 3/99 (3%) Query: 8 NEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQE 67 ++G + G P P EG + +G+ G + D+GE G+ G G Sbjct: 2657 HKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQP---GPKGDQGEKGERGTPGIGGFPG 2713 Query: 68 KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYV 106 G G P G + Q + E+ P + V Sbjct: 2714 PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERV 2752 Score = 27.3 bits (59), Expect = 8.9 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 10/79 (12%) Query: 45 EGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKR-PAE 103 +G++ + GE G GQ+ G GR+ G P Q P S E+ P Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRT---------GAPGPQGPPGSATAKGERGFPGA 1303 Query: 104 DYVPRKAKRKTDRGTDDSP 122 D P R + GT +P Sbjct: 1304 DGRPGSPGRAGNPGTPGAP 1322 Score = 27.3 bits (59), Expect = 8.9 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 11/95 (11%) Query: 6 NKNEGNLENEGKPE---DEVEPDDEGKSDEEEKPDVEGKTECEGK---REDEGEPGDEGQ 59 N ++G + G P D EP G+ P G EGK + G PG G Sbjct: 2122 NGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGG 2181 Query: 60 LEDEGSQEKQGRSEGEGKPQG----EGKPASQAKP 90 D G G + G PQG +G+P P Sbjct: 2182 HGDPGPPGAPGLA-GPAGPQGPSGLKGEPGETGPP 2215 Score = 27.3 bits (59), Expect = 8.9 Identities = 17/55 (30%), Positives = 20/55 (36%) Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78 P G+ E KP G+ GK D G PG G G +G G P Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298 Score = 27.3 bits (59), Expect = 8.9 Identities = 32/122 (26%), Positives = 40/122 (32%), Gaps = 10/122 (8%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69 G + GKP GK + P V G G +GEPG G Q Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTG----APGQAVV 2303 Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDL 129 G +G+ G A E P A R +P K + G P D ED Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGE--PGAKGDRG----LPGPRGEKGEAGRAGEPGDPGEDG 2357 Query: 130 QE 131 Q+ Sbjct: 2358 QK 2359 Score = 27.3 bits (59), Expect = 8.9 Identities = 16/57 (28%), Positives = 24/57 (42%) Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72 G P E + G E+ +P EG G GE G++G + G + +G S Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS 2522 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 47.0 bits (110), Expect = 1e-05 Identities = 40/174 (22%), Positives = 83/174 (47%), Gaps = 9/174 (5%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 EK + K E L E + E EP + + EEE+ + E +RE + E + +L Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE-QLRKLERQELRRERQEEEQQQQRLR 301 Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKR-----KTDR 116 E Q+ + + E E + Q E + Q + E Q E++ + R+ ++ + +R Sbjct: 302 RE--QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359 Query: 117 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQ 170 ++ +E+ +E+ L E+ +R + R +++LR++Q++ ++R+ Q Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQL-RREQQLRREQQLRREQQLRREQQ 412 Score = 40.8 bits (94), Expect = 8e-04 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 14/140 (10%) Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78 E+ E +E + +E + E + E + +RE E E QL E QE++ R + + Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERR--EQQLRRE--QEEERREQQLRRE 367 Query: 79 QGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEE 138 Q E + Q + E Q R ++ E + R+ + + + Q+ +E+ L E+ Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE----------QQLRREQQLRREQ 417 Query: 139 MMRECGDVSRAQEELRKKQK 158 +R + R QEE R +QK Sbjct: 418 QLRREQQLRREQEEERHEQK 437 Score = 39.7 bits (91), Expect = 0.002 Identities = 32/158 (20%), Positives = 71/158 (44%), Gaps = 10/158 (6%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE--GEPGDEGQLEDEGSQEKQG 70 E + ++E E + +EE+ + + + E E +RE + E +E + + ++++ Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371 Query: 71 RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130 R E + + + + + Q + E Q R ++ E + R+ + + ++ + +E + Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431 Query: 131 ERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRD 168 ERH E R + R QEE R W++R+ Sbjct: 432 ERHEQKHEQERREQRLKREQEERR--------DWLKRE 461 Score = 38.9 bits (89), Expect = 0.003 Identities = 34/149 (22%), Positives = 75/149 (50%), Gaps = 10/149 (6%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE-GEPGDEGQLEDEGSQEKQGR 71 + E + E ++ ++E + +++E+ + + + E E +RE +E +L+ E+Q R Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539 Query: 72 SEGEGKPQGEGKPASQAKPESQPRAAE-KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130 E E + + K + + E + R KR E+ + KR+ +R ++ +E L+ Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599 Query: 131 ERHLSSEEMMRECGDVSRAQEELRKKQKM 159 +R + RE +V R ++E R++Q++ Sbjct: 600 QR------LKRE--EVERLEQEERREQRL 620 Score = 38.1 bits (87), Expect = 0.005 Identities = 42/192 (21%), Positives = 82/192 (42%), Gaps = 22/192 (11%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEE-------KPDVEGKTECEGKREDEGEP 54 E+ + + E + + E E + K EEE + + + + E E +RE + Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552 Query: 55 GDEGQLEDEGSQEKQGRSEGEGKPQ---GEGKPASQAKPESQPRAAEKRPAEDYVPR--K 109 +E +LE E +++ R + E + Q E + Q Q E+R + V R + Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612 Query: 110 AKRKTDRGTDDSPKDS----------QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKM 159 +R+ R + P++ QE+ +++ L E+ R + R +EE R +Q++ Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672 Query: 160 GGFHWMQRDVQD 171 H +R Q+ Sbjct: 673 KREHEEERREQE 684 Score = 37.7 bits (86), Expect = 0.007 Identities = 32/132 (24%), Positives = 63/132 (47%), Gaps = 12/132 (9%) Query: 31 DEEEKPDVEGKTEC-EGKREDEG----EPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPA 85 DEE++ +GK + +R++E EP D QLE+E Q ++ + + + + EG+ Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDR-QLEEEPGQRRRQKRQEQERELAEGEEQ 154 Query: 86 SQAKPESQPRAAEKRPAEDYVPRKA-KRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECG 144 S+ + + R ++R E + R+ + + +R ++ S + + EE +R Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR-- 212 Query: 145 DVSRAQEELRKK 156 R ELR+K Sbjct: 213 ---RELLELRRK 221 Score = 37.4 bits (85), Expect = 0.009 Identities = 31/153 (20%), Positives = 66/153 (43%), Gaps = 17/153 (11%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72 + + + E+ E + EE + + E C+G +E ++ + + ++GR Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224 Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRK-AKRKTDRGTDDSPKDSQEDLQE 131 E + Q + E Q R ++ +++ R+ RK + + Q +LQE Sbjct: 225 EKQ-----------QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273 Query: 132 -----RHLSSEEMMRECGDVSRAQEELRKKQKM 159 R L +E+ RE + + Q+ LR++Q++ Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306 Score = 37.4 bits (85), Expect = 0.009 Identities = 35/162 (21%), Positives = 73/162 (45%), Gaps = 13/162 (8%) Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68 E L + + E + + + E E+ ++ + + ++E E + +E QL E QE+ Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR-RQELERKFREEEQLRQETEQEQ 1739 Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128 R E K E Q +PE + + ++ + + + + +R ++ SQE Sbjct: 1740 LRRQERYRKILEE----EQLRPEREEQQLRRQERDRKFREEEQLRQER--EEQQLRSQES 1793 Query: 129 LQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQ 170 +R EE +R+ R +++LR +Q+ G + W + +Q Sbjct: 1794 --DRKFREEEQLRQ----EREEQQLRPQQRDGKYRWEEEQLQ 1829 Score = 37.0 bits (84), Expect = 0.011 Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 5/161 (3%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEG-QL 60 E+ K+E + ++ E D K +EE + + + + + KR+ E E + +L Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491 Query: 61 EDEGSQEKQGRSEGE-GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 119 E+E +E+Q R E + + Q E + + E + R ++ +E + R+ + + ++ Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551 Query: 120 -DSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKM 159 + K +++ +E+ L E+ R D +EE R++Q++ Sbjct: 552 REEEKRLEQERREQRLKREQEERR--DQLLKREEERRQQRL 590 Score = 36.6 bits (83), Expect = 0.015 Identities = 31/149 (20%), Positives = 75/149 (50%), Gaps = 7/149 (4%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72 + E + E ++ + + + +++ + + + + E + +RE + + + E + +E+Q R Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427 Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKA---KRKTDRGTDDSPKDSQEDL 129 E E + + E K + + + R E+R D++ R+ + + +R +D +E+ Sbjct: 428 EQE-EERHEQKHEQERREQRLKREQEER--RDWLKREEETERHEQERRKQQLKRDQEEER 484 Query: 130 QERHLSSEEMMRECGDVSRAQEELRKKQK 158 +ER L EE R R +++LR++Q+ Sbjct: 485 RERWLKLEEEERR-EQQERREQQLRREQE 512 Score = 36.6 bits (83), Expect = 0.015 Identities = 31/175 (17%), Positives = 81/175 (46%), Gaps = 9/175 (5%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 E+P + E + + E+E++ ++E EE + + E + +++DE + +E L Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035 Query: 62 DE------GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTD 115 +E +E+Q R E E + + E + + + + E+ + ++ ++ Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL- 1094 Query: 116 RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQ 170 ++ K +++ + + EE+ +E + R + E R++Q++ + + +VQ Sbjct: 1095 --REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147 Score = 36.6 bits (83), Expect = 0.015 Identities = 32/157 (20%), Positives = 74/157 (47%), Gaps = 12/157 (7%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 E+ + LE + + E+E++ ++E EE + + E + + E+E + +E L Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125 Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDS 121 +E +EK+ R E E Q + E + + E++ + ++ +++ +R + Sbjct: 1126 EE--REKRRRQELE----------RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173 Query: 122 PKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158 + QE+ Q E+ +E R +EEL+++++ Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210 Score = 35.4 bits (80), Expect = 0.033 Identities = 33/151 (21%), Positives = 69/151 (45%), Gaps = 9/151 (5%) Query: 17 KPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG-RSEGE 75 + E + +E +++EE+ +G E E++ + +L +G +EKQ R E + Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234 Query: 76 GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAK--------RKTDRGTDDSPKDSQE 127 + E + K E+ R E++ E+ R+ + RK +R + +E Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294 Query: 128 DLQERHLSSEEMMRECGDVSRAQEELRKKQK 158 Q+R +++ R+ + R Q+E R++Q+ Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQEERREQQ 325 Score = 35.4 bits (80), Expect = 0.033 Identities = 27/158 (17%), Positives = 75/158 (47%), Gaps = 5/158 (3%) Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78 E+E + EEE+ + + + E + +RE + + + E + +E+Q R E + + Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415 Query: 79 QGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEE 138 + + + Q + E + E++ ++ ++ KR+ + D ++ + + E+ ++ Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475 Query: 139 MMRECGDVSR-----AQEELRKKQKMGGFHWMQRDVQD 171 + R+ + R +EE R++Q+ ++R+ ++ Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513 Score = 35.0 bits (79), Expect = 0.043 Identities = 26/118 (22%), Positives = 54/118 (45%), Gaps = 6/118 (5%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 E+P + E + + E+E++ ++E EE + + E + + E+E + +E L Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155 Query: 62 DEGSQ------EKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 113 +E + E+Q R E E + + E + + Q R + R E+ +K K++ Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213 Score = 32.3 bits (72), Expect = 0.28 Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 26/168 (15%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKP--------------DVEGKTECEGKREDEG 52 + E LE K E E E ++ ++EE++ +E + + + Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722 Query: 53 EPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPR-KAK 111 EGQ + +EK+ R E E + Q E + Q + E Q R D+ + +A+ Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR--------DFTWQWQAE 774 Query: 112 RKTDRGTDD-SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158 K++RG S + + +ER L +EE R+ + EE K+Q+ Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEE--RQQREQRFLPEEEEKEQR 820 Score = 32.3 bits (72), Expect = 0.28 Identities = 35/182 (19%), Positives = 80/182 (43%), Gaps = 30/182 (16%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSD-------EEEKPDVEGKTECEGKREDEGEP 54 E+ Y + E E + + + D++ +SD E+E + K C+G+ ++ Sbjct: 1196 ERQYREEE---ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252 Query: 55 GDEGQLEDEGSQ--------EKQGRSEGEGKPQGEGK----PASQAKPESQPRAAEKRPA 102 ++ QL D SQ E+Q R + + + + + P + + + A++R Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312 Query: 103 EDYVPR------KAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKK 156 + + + +++ + TD ++ ++ LQER + + R+ D +EELR + Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER--EEQPLRRQERDRKFREEELRHQ 1370 Query: 157 QK 158 ++ Sbjct: 1371 EQ 1372 Score = 32.3 bits (72), Expect = 0.28 Identities = 28/158 (17%), Positives = 71/158 (44%), Gaps = 7/158 (4%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEP-GDEGQL 60 ++ + ++E L+ + E ++ + + EE+P + + + R D +E QL Sbjct: 1618 DRKFREDEQLLQE--REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL 1675 Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120 EG +++ R E + K + E + + + E + E++ + RK + + + Sbjct: 1676 LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET 1735 Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158 + + + R + EE +R R +++LR++++ Sbjct: 1736 EQEQLRRQERYRKILEEEQLRP----EREEQQLRRQER 1769 Score = 31.2 bits (69), Expect = 0.61 Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 7/161 (4%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 E+ + E L E E+ E + +EE + + + E +RE + + + E Sbjct: 329 EQQEERREQQLRRE--QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386 Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDS 121 + +E+Q R E + + + + + Q + E Q R ++ E R ++ + Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446 Query: 122 PKDSQED-----LQERHLSSEEMMRECGDVSRAQEELRKKQ 157 K QE+ +E E R + R QEE R+++ Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487 Score = 29.6 bits (65), Expect = 1.8 Identities = 35/162 (21%), Positives = 66/162 (40%), Gaps = 13/162 (8%) Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQ 66 + E L EG+ E ++ + + EE+ + + E E K E + +LE + + Sbjct: 1670 REEEQLLQEGE-EQQLRRQERDRKFREEEQQLR-RQERERKFLQEEQQLRRQELERKFRE 1727 Query: 67 EKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQ 126 E+Q R E E Q + Q R + E P + +++ R D + Sbjct: 1728 EEQLRQETE-----------QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776 Query: 127 EDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRD 168 E L++ + +E R +E+LR++++ QRD Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818 Score = 28.5 bits (62), Expect = 4.0 Identities = 29/179 (16%), Positives = 81/179 (45%), Gaps = 33/179 (18%) Query: 13 ENEGKPEDEVEPDDEGKSDEE------EKPDVEGKTECEGKREDEGEPGDEGQL------ 60 E + + +DE++ ++E EE ++ + + + E E ++E+E G+E + Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076 Query: 61 ------EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 114 E+E QE++ E + + + Q + E + + E++ + ++ +++ Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136 Query: 115 DRG---------------TDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158 +R ++ K +++L+ ++ EE+ +E + R ++E R++++ Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195 >gi|171916097 repetin [Homo sapiens] Length = 784 Score = 47.0 bits (110), Expect = 1e-05 Identities = 25/98 (25%), Positives = 53/98 (54%), Gaps = 6/98 (6%) Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK--REDE----GEPGDEGQ 59 N + G + +G+ + D +G+S +PD +G++ GK R+D+ G+P +GQ Sbjct: 448 NSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQ 507 Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97 G ++QG+S G+P +G+ + ++ + Q +++ Sbjct: 508 SSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSS 545 Score = 42.4 bits (98), Expect = 3e-04 Identities = 19/89 (21%), Positives = 47/89 (52%) Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68 +G + G+P+ + + G++D +++ G+TE +G+ + +GQ G ++ Sbjct: 373 QGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432 Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAA 97 QG+S G+P +G+ + + + Q +++ Sbjct: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQSS 461 Score = 42.4 bits (98), Expect = 3e-04 Identities = 19/85 (22%), Positives = 44/85 (51%) Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68 +G + G+P+ + + G++D + + G+T+ +G+ +P +GQ G ++ Sbjct: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDR 492 Query: 69 QGRSEGEGKPQGEGKPASQAKPESQ 93 Q +S G+P G+G+ + + + Q Sbjct: 493 QDQSYHYGQPDGQGQSSHYGQTDRQ 517 Score = 39.7 bits (91), Expect = 0.002 Identities = 20/88 (22%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69 G E +G+ + D +G+ G+T+ +G+ G+P +GQ G ++Q Sbjct: 404 GQTERQGQSSHYSQMDRQGQGSHY------GQTDRQGQSSHYGQPDRQGQNSHYGQTDRQ 457 Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAA 97 G+S G+ +G+ + ++P+ Q +++ Sbjct: 458 GQSSHYGQTDRQGQSSHYSQPDKQGQSS 485 Score = 37.4 bits (85), Expect = 0.009 Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 12 LENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQ----- 66 ++ +G+ + D +G+S +PD +G+ G+ + +G+ GQ + +G Sbjct: 418 MDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQ 477 Query: 67 -EKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97 +KQG+S GK + + +P+ Q +++ Sbjct: 478 PDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSS 509 Score = 35.4 bits (80), Expect = 0.033 Identities = 15/68 (22%), Positives = 36/68 (52%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69 G + +G+ +PD +G+S + D +G++ G+ + +G+ GQ + +G Sbjct: 512 GQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHY 571 Query: 70 GRSEGEGK 77 G+++ +G+ Sbjct: 572 GQTDRQGQ 579 Score = 35.0 bits (79), Expect = 0.043 Identities = 19/95 (20%), Positives = 46/95 (48%), Gaps = 8/95 (8%) Query: 5 YNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEG 64 Y+ ++ N + +G + P+ +G+S +PD + ++ G+ + + + GQ E +G Sbjct: 353 YHYDQTNRQGQGSHYSQ--PNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQG 410 Query: 65 SQ------EKQGRSEGEGKPQGEGKPASQAKPESQ 93 ++QG+ G+ +G+ + +P+ Q Sbjct: 411 QSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445 Score = 34.7 bits (78), Expect = 0.056 Identities = 18/85 (21%), Positives = 41/85 (48%) Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68 +G + GK + + + G+ D + + G+T+ +G+ G+P +GQ ++ Sbjct: 481 QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR 540 Query: 69 QGRSEGEGKPQGEGKPASQAKPESQ 93 QG+S G+ +G+ + + + Q Sbjct: 541 QGQSSHYGQTDRQGQSSHYGQTDRQ 565 Score = 33.9 bits (76), Expect = 0.095 Identities = 18/94 (19%), Positives = 44/94 (46%), Gaps = 6/94 (6%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE------PGDEGQLEDE 63 G + +G+ + D +G+S +PD +G++ G+ + +G+ +GQ Sbjct: 308 GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHY 367 Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97 +QG+S G+P + + + + + Q +++ Sbjct: 368 SQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSS 401 Score = 33.9 bits (76), Expect = 0.095 Identities = 16/80 (20%), Positives = 39/80 (48%) Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69 G + +G+ + D +G+S +PD +G++ + + +G+ GQ + +G Sbjct: 500 GQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHY 559 Query: 70 GRSEGEGKPQGEGKPASQAK 89 G+++ +G+ G+ Q + Sbjct: 560 GQTDRQGQSYHYGQTDRQGQ 579 Score = 32.7 bits (73), Expect = 0.21 Identities = 37/182 (20%), Positives = 73/182 (40%), Gaps = 24/182 (13%) Query: 14 NEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEG----SQEKQ 69 + G+PE + G+S+++++ + E R+D ++ + +D+ E+Q Sbjct: 145 HHGQPERQDRDSHHGQSEKQDRDSHHSQPE----RQDRDSHHNQSERQDKDFSFDQSERQ 200 Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAAEK--RPAEDYVPRKAKRKTDRGTDDSPKDSQE 127 + GK + QAK + A + +P +D +++R T + S+ Sbjct: 201 SQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT--------QQSET 252 Query: 128 DLQERHLSSEEMMRE---CGDVSRAQEEL---RKKQKMGGFHWMQRDVQDPFAPRGQRGV 181 Q H + + CG R +EL + ++ H+ Q D QD GQ Sbjct: 253 LGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDR 312 Query: 182 RG 183 +G Sbjct: 313 QG 314 Score = 30.4 bits (67), Expect = 1.0 Identities = 26/132 (19%), Positives = 54/132 (40%), Gaps = 13/132 (9%) Query: 6 NKNEGNLENEGKPEDEVEPDDE--GKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63 NK+ G ++ + E D + G + + + E + + + E + GD Sbjct: 91 NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS----HH 146 Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123 G E+Q R G+ + + + + ++PE Q R + +E ++ D D S + Sbjct: 147 GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSE-------RQDKDFSFDQSER 199 Query: 124 DSQEDLQERHLS 135 SQ+ + +S Sbjct: 200 QSQDSSSGKKVS 211 Score = 30.0 bits (66), Expect = 1.4 Identities = 34/172 (19%), Positives = 71/172 (41%), Gaps = 13/172 (7%) Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGE 75 G+ + + + G++D +++ G+T+ +G+ + +GQ ++QG+S Sbjct: 284 GQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHY 343 Query: 76 GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS----QEDLQE 131 G+ +G+ + Q + + P + + + G D+ S Q D Q+ Sbjct: 344 GQMDRKGQCYHYDQTNRQGQGSHYSQ-----PNRQGQSSHYGQPDTQDQSSHYGQTDRQD 398 Query: 132 RHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRG 183 + + R+ G S + R+ Q G H+ Q D Q + GQ +G Sbjct: 399 QSSHYGQTERQ-GQSSHYSQMDRQGQ---GSHYGQTDRQGQSSHYGQPDRQG 446 Score = 30.0 bits (66), Expect = 1.4 Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 6/91 (6%) Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEG------KTECEGKREDEGEPGDEGQLEDEGSQ 66 + +G+ +PD +G+S + D +G +T +G+ +P +GQ G Sbjct: 323 DRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQP 382 Query: 67 EKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97 + Q +S G+ + + + + E Q +++ Sbjct: 383 DTQDQSSHYGQTDRQDQSSHYGQTERQGQSS 413 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 46.6 bits (109), Expect = 1e-05 Identities = 43/166 (25%), Positives = 75/166 (45%), Gaps = 14/166 (8%) Query: 12 LENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL-EDEGSQEKQG 70 L +P +E E + + + D KTE E + E+E E DE + +DEG + ++ Sbjct: 239 LSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREA 298 Query: 71 RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130 E K +GE P + KPE ++RP ++ + R T SQE+ + Sbjct: 299 PILKEFKEEGEEIP--RVKPEEM---MDERPKTRSQEQEVLERGGRFT-----RSQEEAR 348 Query: 131 ERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPR 176 + HL+ ++ +E S +EE R+ + G ++ + P PR Sbjct: 349 KSHLARQQQEKEMKTTSPLEEEEREIKSSQG---LKEKSKSPSPPR 391 Score = 28.1 bits (61), Expect = 5.2 Identities = 38/171 (22%), Positives = 62/171 (36%), Gaps = 14/171 (8%) Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTEC------EGKREDEGEP 54 +EK LE E + E+E DE P EG E E Sbjct: 141 LEKQQELLRQRLEREAREAAELEEASAESEDEMIHP--EGVASLLPPDFQSSLERPELEL 198 Query: 55 GDEGQLEDEGSQEKQGRSEGEGKPQGEG-----KPASQAKPESQPRAAEKRPAEDYVPRK 109 + E++G S+ E +GE + A AK + AE+ ++ R Sbjct: 199 SRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRN 258 Query: 110 AKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMG 160 + + DR ++ +E+ +E EE E G SR L++ ++ G Sbjct: 259 LRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDE-GQKSREAPILKEFKEEG 308 Score = 28.1 bits (61), Expect = 5.2 Identities = 19/93 (20%), Positives = 42/93 (45%), Gaps = 6/93 (6%) Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61 E+ + E E + + E E E + + + E++ + + + E +RE E + GD + Sbjct: 1247 EREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDR-- 1304 Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQP 94 ++ R G + + + K S+++ S P Sbjct: 1305 ----DRERDRERGRERDRRDTKRHSRSRSRSTP 1333 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.303 0.130 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,459,812 Number of Sequences: 37866 Number of extensions: 652275 Number of successful extensions: 16576 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 631 Number of HSP's successfully gapped in prelim test: 693 Number of HSP's that attempted gapping in prelim test: 4138 Number of HSP's gapped (non-prelim): 7388 length of query: 200 length of database: 18,247,518 effective HSP length: 97 effective length of query: 103 effective length of database: 14,574,516 effective search space: 1501175148 effective search space used: 1501175148 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.