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Search of human proteins with 54792129
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
sapiens]
(775 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa... 1593 0.0
gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo sa... 345 7e-95
gi|31317224 EGF-like repeats and discoidin I-like domains-contai... 139 8e-33
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 138 2e-32
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 138 2e-32
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 138 2e-32
gi|105990535 coagulation factor V precursor [Homo sapiens] 136 6e-32
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho... 134 3e-31
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 128 2e-29
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 128 2e-29
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 128 2e-29
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 128 2e-29
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 128 2e-29
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 128 2e-29
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa... 120 5e-27
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap... 120 5e-27
gi|10835083 X-linked juvenile retinoschisis protein precursor [H... 102 2e-21
gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Ho... 87 8e-17
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 86 1e-16
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 85 2e-16
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 84 4e-16
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 83 1e-15
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 80 9e-15
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap... 79 2e-14
gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu... 78 3e-14
gi|126091152 cubilin [Homo sapiens] 78 4e-14
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho... 77 8e-14
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom... 77 8e-14
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho... 77 8e-14
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom... 77 8e-14
>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
sapiens]
Length = 775
Score = 1593 bits (4125), Expect = 0.0
Identities = 775/775 (100%), Positives = 775/775 (100%)
Query: 1 MASRAVVRARRCPQCPQVRAAAAAPAWAALPLSRSLPPCSNSSSFSMPLFLLLLLVLLLL 60
MASRAVVRARRCPQCPQVRAAAAAPAWAALPLSRSLPPCSNSSSFSMPLFLLLLLVLLLL
Sbjct: 1 MASRAVVRARRCPQCPQVRAAAAAPAWAALPLSRSLPPCSNSSSFSMPLFLLLLLVLLLL 60
Query: 61 LEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDI 120
LEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDI
Sbjct: 61 LEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDI 120
Query: 121 EDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF 180
EDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF
Sbjct: 121 EDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF 180
Query: 181 LASYSVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAG 240
LASYSVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAG
Sbjct: 181 LASYSVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAG 240
Query: 241 VHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMES 300
VHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMES
Sbjct: 241 VHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMES 300
Query: 301 GVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKK 360
GVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKK
Sbjct: 301 GVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKK 360
Query: 361 ITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNF 420
ITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNF
Sbjct: 361 ITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNF 420
Query: 421 LPPIIARFIRVNPTQWQQKIAMKMELLGCQFIPKGRPPKLTQPPPPRNSNDLKNTTAPPK 480
LPPIIARFIRVNPTQWQQKIAMKMELLGCQFIPKGRPPKLTQPPPPRNSNDLKNTTAPPK
Sbjct: 421 LPPIIARFIRVNPTQWQQKIAMKMELLGCQFIPKGRPPKLTQPPPPRNSNDLKNTTAPPK 480
Query: 481 IAKGRAPKFTQPLQPRSSNEFPAQTEQTTASPDIRNTTVTPNVTKDVALAAVLVPVLVMV 540
IAKGRAPKFTQPLQPRSSNEFPAQTEQTTASPDIRNTTVTPNVTKDVALAAVLVPVLVMV
Sbjct: 481 IAKGRAPKFTQPLQPRSSNEFPAQTEQTTASPDIRNTTVTPNVTKDVALAAVLVPVLVMV 540
Query: 541 LTTLILILVCAWHWRNRKKKTEGTYDLPYWDRAGWWKGMKQFLPAKAVDHEETPVRYSSS 600
LTTLILILVCAWHWRNRKKKTEGTYDLPYWDRAGWWKGMKQFLPAKAVDHEETPVRYSSS
Sbjct: 541 LTTLILILVCAWHWRNRKKKTEGTYDLPYWDRAGWWKGMKQFLPAKAVDHEETPVRYSSS 600
Query: 601 EVNHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPGQ 660
EVNHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPGQ
Sbjct: 601 EVNHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPGQ 660
Query: 661 EVYHAYAEPLPITGPEYATPIIMDMSGHPTTSVGQPSTSTFKATGNQPPPLVGTYNTLLS 720
EVYHAYAEPLPITGPEYATPIIMDMSGHPTTSVGQPSTSTFKATGNQPPPLVGTYNTLLS
Sbjct: 661 EVYHAYAEPLPITGPEYATPIIMDMSGHPTTSVGQPSTSTFKATGNQPPPLVGTYNTLLS 720
Query: 721 RTDSCSSAQAQYDTPKAGKPGLPAPDELVYQVPQSTQEVSGAGRDGECDVFKEIL 775
RTDSCSSAQAQYDTPKAGKPGLPAPDELVYQVPQSTQEVSGAGRDGECDVFKEIL
Sbjct: 721 RTDSCSSAQAQYDTPKAGKPGLPAPDELVYQVPQSTQEVSGAGRDGECDVFKEIL 775
>gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo
sapiens]
Length = 539
Score = 345 bits (886), Expect = 7e-95
Identities = 182/404 (45%), Positives = 255/404 (63%), Gaps = 14/404 (3%)
Query: 51 LLLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGER 110
L LLL + L + GDGCGH V +SGT+TS NYP TYPN TVCE I V G+R
Sbjct: 20 LALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKR 79
Query: 111 VRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFM 170
+ ++ GD DIE S +C +YL + S + G YCG + + + +E+T+ F
Sbjct: 80 LILRLGDLDIE-SQTCASDYLLFTS----SSDQYGPYCG-SMTVPKELLLNTSEVTVRFE 133
Query: 171 SGIHVSGRGFLASYSVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGY 230
SG H+SGRGFL +Y+ D DLITCL+ AS++L+ E+SK+CPAGC +ISG + GY
Sbjct: 134 SGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRDVAGDISGNMVDGY 193
Query: 231 RDSSPLCMAGVHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTS 290
RD+S LC A +HAG++++ LGGQISV+ KGI YE LAN V S G LS F F ++
Sbjct: 194 RDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRDGSLSDKRFLFTSN 253
Query: 291 GCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDE--- 347
GC +L E D QI ASS + + +G + W P +ARL+ GP WA+ +
Sbjct: 254 GCSRSLSFE----PDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHK 309
Query: 348 -YQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIF 406
+WL+IDL ++KKITGI TTGST N+YV ++ + + ++ KW Y+ ++K+F
Sbjct: 310 PREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVF 369
Query: 407 QGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450
QGN ++ V+NNF+PPI+AR++RV P W Q+IA+K+EL+GCQ
Sbjct: 370 QGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQ 413
>gi|31317224 EGF-like repeats and discoidin I-like
domains-containing protein 3 [Homo sapiens]
Length = 480
Score = 139 bits (351), Expect = 8e-33
Identities = 75/172 (43%), Positives = 102/172 (59%), Gaps = 4/172 (2%)
Query: 280 LSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGP- 338
L L + SGC LGM+SG I D QITASS+ + +W+P+KARL K G
Sbjct: 307 LRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNM--DMFTWEPRKARLDKQGKV 364
Query: 339 -PWAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYRE 397
W + D+ QWLQ+DL K+TGIIT G+ H +V +Y++ YS+DG+ WTVY++
Sbjct: 365 NAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQD 424
Query: 398 PGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449
+DK+FQGN D +N PPI AR IR+ P W +I ++ ELLGC
Sbjct: 425 EKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGC 476
Score = 126 bits (317), Expect = 7e-29
Identities = 61/161 (37%), Positives = 96/161 (59%), Gaps = 5/161 (3%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPG--PPWAAFATDEYQ 349
C G LG+E G+I++ QITASS W P ARL K G W A D +
Sbjct: 158 CSGPLGIEGGIISNQQITASSTHRALFGL---QKWYPYYARLNKKGLINAWTAAENDRWP 214
Query: 350 WLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGN 409
W+QI+L ++ ++TG+IT G+ + Y+ +Y+I YS+DG+ W +Y+ G +D +F+GN
Sbjct: 215 WIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGN 274
Query: 410 KDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450
D + N+F PPI A+++R+ P ++ ++MELLGC+
Sbjct: 275 IDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCE 315
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 138 bits (347), Expect = 2e-32
Identities = 123/444 (27%), Positives = 189/444 (42%), Gaps = 70/444 (15%)
Query: 52 LLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMG-ER 110
LL VL L+L AGA + D CG T+ G LTS YP +Y S CEW I+ +R
Sbjct: 7 LLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQR 66
Query: 111 VRIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLF 169
+ I F FD+ED D C ++Y+ +++G + GK+CG + S G + + F
Sbjct: 67 IMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAPP--PVVSSGPFLFIKF 123
Query: 170 MSGIHVSGRGFLASYSVIDK------------------------QDLITC---------- 195
+S G GF Y + + + + C
Sbjct: 124 VSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMS 183
Query: 196 ---LDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVS----N 248
L+ S LEP+ + P G + + I G+ D P G + G +
Sbjct: 184 EIILEFESFDLEPDSNP--PGGMFCRYDRLE--IWDGFPDVGP--HIGRYCGQKTPGRIR 237
Query: 249 TLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQI 308
+ G +S+V + + N + + +S FK C LGMESG I QI
Sbjct: 238 SSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED---FK---CMEALGMESGEIHSDQI 291
Query: 309 TASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG 368
TASS +W +++RL P W +W+Q+DL + +T + T G
Sbjct: 292 TASSQYS--------TNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG 343
Query: 369 STMVE--HNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIA 426
+ E YYV Y+I S +G+ W +E + +FQGN + V F P+I
Sbjct: 344 AISKETKKKYYVKTYKIDVSSNGEDWITIKEGN--KPVLFQGNTNPTDVVVAVFPKPLIT 401
Query: 427 RFIRVNPTQWQQKIAMKMELLGCQ 450
RF+R+ P W+ I+M+ E+ GC+
Sbjct: 402 RFVRIKPATWETGISMRFEVYGCK 425
Score = 92.4 bits (228), Expect = 1e-18
Identities = 59/163 (36%), Positives = 86/163 (52%), Gaps = 13/163 (7%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAF-ATDEY-- 348
C G LGM SG+I+D QIT+S+ G N W P+ RL WA A Y
Sbjct: 431 CSGMLGMVSGLISDSQITSSN-------QGDRN-WMPENIRLVTSRSGWALPPAPHSYIN 482
Query: 349 QWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQG 408
+WLQIDL +EK + GII G E+ ++ ++I YS++G W + + + K F+G
Sbjct: 483 EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEG 542
Query: 409 NKDYHQDVRNNFLPPIIARFIRVNPTQ-WQQKIAMKMELLGCQ 450
N +Y F P + RFIR+ P + + ++MELLGC+
Sbjct: 543 NNNYDTPELRTF-PALSTRFIRIYPERATHGGLGLRMELLGCE 584
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 138 bits (347), Expect = 2e-32
Identities = 123/444 (27%), Positives = 189/444 (42%), Gaps = 70/444 (15%)
Query: 52 LLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMG-ER 110
LL VL L+L AGA + D CG T+ G LTS YP +Y S CEW I+ +R
Sbjct: 7 LLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQR 66
Query: 111 VRIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLF 169
+ I F FD+ED D C ++Y+ +++G + GK+CG + S G + + F
Sbjct: 67 IMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAPP--PVVSSGPFLFIKF 123
Query: 170 MSGIHVSGRGFLASYSVIDK------------------------QDLITC---------- 195
+S G GF Y + + + + C
Sbjct: 124 VSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMS 183
Query: 196 ---LDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVS----N 248
L+ S LEP+ + P G + + I G+ D P G + G +
Sbjct: 184 EIILEFESFDLEPDSNP--PGGMFCRYDRLE--IWDGFPDVGP--HIGRYCGQKTPGRIR 237
Query: 249 TLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQI 308
+ G +S+V + + N + + +S FK C LGMESG I QI
Sbjct: 238 SSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED---FK---CMEALGMESGEIHSDQI 291
Query: 309 TASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG 368
TASS +W +++RL P W +W+Q+DL + +T + T G
Sbjct: 292 TASSQYS--------TNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG 343
Query: 369 STMVE--HNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIA 426
+ E YYV Y+I S +G+ W +E + +FQGN + V F P+I
Sbjct: 344 AISKETKKKYYVKTYKIDVSSNGEDWITIKEGN--KPVLFQGNTNPTDVVVAVFPKPLIT 401
Query: 427 RFIRVNPTQWQQKIAMKMELLGCQ 450
RF+R+ P W+ I+M+ E+ GC+
Sbjct: 402 RFVRIKPATWETGISMRFEVYGCK 425
Score = 92.4 bits (228), Expect = 1e-18
Identities = 59/163 (36%), Positives = 86/163 (52%), Gaps = 13/163 (7%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAF-ATDEY-- 348
C G LGM SG+I+D QIT+S+ G N W P+ RL WA A Y
Sbjct: 431 CSGMLGMVSGLISDSQITSSN-------QGDRN-WMPENIRLVTSRSGWALPPAPHSYIN 482
Query: 349 QWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQG 408
+WLQIDL +EK + GII G E+ ++ ++I YS++G W + + + K F+G
Sbjct: 483 EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEG 542
Query: 409 NKDYHQDVRNNFLPPIIARFIRVNPTQ-WQQKIAMKMELLGCQ 450
N +Y F P + RFIR+ P + + ++MELLGC+
Sbjct: 543 NNNYDTPELRTF-PALSTRFIRIYPERATHGGLGLRMELLGCE 584
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 138 bits (347), Expect = 2e-32
Identities = 123/444 (27%), Positives = 189/444 (42%), Gaps = 70/444 (15%)
Query: 52 LLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMG-ER 110
LL VL L+L AGA + D CG T+ G LTS YP +Y S CEW I+ +R
Sbjct: 7 LLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQR 66
Query: 111 VRIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLF 169
+ I F FD+ED D C ++Y+ +++G + GK+CG + S G + + F
Sbjct: 67 IMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAPP--PVVSSGPFLFIKF 123
Query: 170 MSGIHVSGRGFLASYSVIDK------------------------QDLITC---------- 195
+S G GF Y + + + + C
Sbjct: 124 VSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMS 183
Query: 196 ---LDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVS----N 248
L+ S LEP+ + P G + + I G+ D P G + G +
Sbjct: 184 EIILEFESFDLEPDSNP--PGGMFCRYDRLE--IWDGFPDVGP--HIGRYCGQKTPGRIR 237
Query: 249 TLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQI 308
+ G +S+V + + N + + +S FK C LGMESG I QI
Sbjct: 238 SSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED---FK---CMEALGMESGEIHSDQI 291
Query: 309 TASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG 368
TASS +W +++RL P W +W+Q+DL + +T + T G
Sbjct: 292 TASSQYS--------TNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG 343
Query: 369 STMVE--HNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIA 426
+ E YYV Y+I S +G+ W +E + +FQGN + V F P+I
Sbjct: 344 AISKETKKKYYVKTYKIDVSSNGEDWITIKEGN--KPVLFQGNTNPTDVVVAVFPKPLIT 401
Query: 427 RFIRVNPTQWQQKIAMKMELLGCQ 450
RF+R+ P W+ I+M+ E+ GC+
Sbjct: 402 RFVRIKPATWETGISMRFEVYGCK 425
Score = 92.4 bits (228), Expect = 1e-18
Identities = 59/163 (36%), Positives = 86/163 (52%), Gaps = 13/163 (7%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAF-ATDEY-- 348
C G LGM SG+I+D QIT+S+ G N W P+ RL WA A Y
Sbjct: 431 CSGMLGMVSGLISDSQITSSN-------QGDRN-WMPENIRLVTSRSGWALPPAPHSYIN 482
Query: 349 QWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQG 408
+WLQIDL +EK + GII G E+ ++ ++I YS++G W + + + K F+G
Sbjct: 483 EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEG 542
Query: 409 NKDYHQDVRNNFLPPIIARFIRVNPTQ-WQQKIAMKMELLGCQ 450
N +Y F P + RFIR+ P + + ++MELLGC+
Sbjct: 543 NNNYDTPELRTF-PALSTRFIRIYPERATHGGLGLRMELLGCE 584
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 136 bits (343), Expect = 6e-32
Identities = 77/166 (46%), Positives = 98/166 (59%), Gaps = 10/166 (6%)
Query: 288 KTSGCYGTLGMESGVIADPQITASSVLE--WTDHTGQENSWKPKKARLKKPGP--PWAAF 343
+ +GC LGME+G I + QITASS + W D+ W+P +ARL G W A
Sbjct: 2062 EVNGCSTPLGMENGKIENKQITASSFKKSWWGDY------WEPFRARLNAQGRVNAWQAK 2115
Query: 344 ATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQD 403
A + QWL+IDL K KKIT IIT G + YV +Y I YS+ G +W YR D
Sbjct: 2116 ANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVD 2175
Query: 404 KIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449
KIF+GN + V+N F PPII+RFIRV P W Q IA+++EL GC
Sbjct: 2176 KIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGC 2221
Score = 94.0 bits (232), Expect = 5e-19
Identities = 55/174 (31%), Positives = 86/174 (49%), Gaps = 19/174 (10%)
Query: 285 FTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGP--PW-- 340
F C +G+ +G+I+D QI AS L + W+P+ ARL G W
Sbjct: 1900 FLIMDRDCRMPMGLSTGIISDSQIKASEFLGY---------WEPRLARLNNGGSYNAWSV 1950
Query: 341 ----AAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYR 396
A FA+ W+Q+D+ KE ITGI T G+ + Y + + + YS + W +++
Sbjct: 1951 EKLAAEFASKP--WIQVDMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFK 2008
Query: 397 EPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450
F GN D N F PPI+AR+IR++PT+ + +++EL GC+
Sbjct: 2009 GNSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCE 2062
>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
sapiens]
Length = 387
Score = 134 bits (337), Expect = 3e-31
Identities = 71/173 (41%), Positives = 99/173 (57%), Gaps = 6/173 (3%)
Query: 280 LSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLE-WTDHTGQENSWKPKKARLKKPGP 338
L L + +GC LG+++ I D QITASS + W H SW P ARL K G
Sbjct: 218 LRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLF---SWNPSYARLDKQGN 274
Query: 339 --PWAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYR 396
W A + QWLQ+DL K++TGIIT G+ +V++Y++ YS+D WT Y+
Sbjct: 275 FNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQ 334
Query: 397 EPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449
+P KIF GN D H +N F PI+AR++R+ P W +IA+++ELLGC
Sbjct: 335 DPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 387
Score = 86.7 bits (213), Expect = 8e-17
Identities = 50/161 (31%), Positives = 90/161 (55%), Gaps = 6/161 (3%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGP--PWAAFATDEYQ 349
C LG+E+G IA+ QI ASSV G ++ W P+ ARL + G W + D+
Sbjct: 70 CVEPLGLENGNIANSQIAASSVR--VTFLGLQH-WVPELARLNRAGMVNAWTPSSNDDNP 126
Query: 350 WLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGN 409
W+Q++L + +TG++T G++ + + Y+ A+++ YS +G ++ + ++ K F GN
Sbjct: 127 WIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVN-KKHKEFVGN 185
Query: 410 KDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450
+ + N F P+ A+++R+ PT ++ ELLGC+
Sbjct: 186 WNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 128 bits (321), Expect = 2e-29
Identities = 112/440 (25%), Positives = 190/440 (43%), Gaps = 62/440 (14%)
Query: 53 LLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRV-KMGERV 111
+ L L Q CG + ++G +TS YPQ YP+ CEW + + +++
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 112 RIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCG-------------LGLQMNHS 157
+ F F+IE D C ++++ I +G S +GK+CG L ++
Sbjct: 69 VLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 158 IESKGNEITL---LFMSGIHVSGRGFLA--------------------SYSVIDKQDLIT 194
+G +L +F +G + F + +++++ K +
Sbjct: 128 YARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEI 187
Query: 195 CLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQI 254
L LE + + C + +I IPH C + + S+T G +
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSST--GIL 245
Query: 255 SVVISKGIPYYESSLANNVTSVVGHL--STSLFTFKTSGCYGTLGMESGVIADPQITASS 312
S+ + + ++A + S +L L F+ C LGMESG IA+ QI+ASS
Sbjct: 246 SLTF-----HTDMAVAKDGFSARYYLVHQEPLENFQ---CNVPLGMESGRIANEQISASS 297
Query: 313 VLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG--ST 370
T + W P+++RL W ++LQ+DL +T I T G S
Sbjct: 298 -------TYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISR 350
Query: 371 MVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIR 430
++ YYV +Y++ S +G+ W VYR + K+FQ N D + V N P++ RF+R
Sbjct: 351 ETQNGYYVKSYKLEVSTNGEDWMVYRHG--KNHKVFQANNDATEVVLNKLHAPLLTRFVR 408
Query: 431 VNPTQWQQKIAMKMELLGCQ 450
+ P W IA+++EL GC+
Sbjct: 409 IRPQTWHSGIALRLELFGCR 428
Score = 99.4 bits (246), Expect = 1e-20
Identities = 62/171 (36%), Positives = 89/171 (52%), Gaps = 21/171 (12%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPW---AAFATDEY 348
C LGM SG+IAD QI+ASS QE W P ARL W A
Sbjct: 434 CSNMLGMLSGLIADSQISASST--------QEYLWSPSAARLVSSRSGWFPRIPQAQPGE 485
Query: 349 QWLQIDLNKEKKITGIITTGS------TMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQ 402
+WLQ+DL K + G+I G+ T VE +V +++ YS +G+ W ++P +Q
Sbjct: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQ 545
Query: 403 DKIFQGNKDYH-QDVRNNFLPPIIARFIRVNPTQWQQK-IAMKMELLGCQF 451
K+F+GN Y D+R PI A+++RV P +W I M++E+LGC +
Sbjct: 546 PKLFEGNMHYDTPDIRR--FDPIPAQYVRVYPERWSPAGIGMRLEVLGCDW 594
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 128 bits (321), Expect = 2e-29
Identities = 112/440 (25%), Positives = 190/440 (43%), Gaps = 62/440 (14%)
Query: 53 LLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRV-KMGERV 111
+ L L Q CG + ++G +TS YPQ YP+ CEW + + +++
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 112 RIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCG-------------LGLQMNHS 157
+ F F+IE D C ++++ I +G S +GK+CG L ++
Sbjct: 69 VLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 158 IESKGNEITL---LFMSGIHVSGRGFLA--------------------SYSVIDKQDLIT 194
+G +L +F +G + F + +++++ K +
Sbjct: 128 YARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEI 187
Query: 195 CLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQI 254
L LE + + C + +I IPH C + + S+T G +
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSST--GIL 245
Query: 255 SVVISKGIPYYESSLANNVTSVVGHL--STSLFTFKTSGCYGTLGMESGVIADPQITASS 312
S+ + + ++A + S +L L F+ C LGMESG IA+ QI+ASS
Sbjct: 246 SLTF-----HTDMAVAKDGFSARYYLVHQEPLENFQ---CNVPLGMESGRIANEQISASS 297
Query: 313 VLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG--ST 370
T + W P+++RL W ++LQ+DL +T I T G S
Sbjct: 298 -------TYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISR 350
Query: 371 MVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIR 430
++ YYV +Y++ S +G+ W VYR + K+FQ N D + V N P++ RF+R
Sbjct: 351 ETQNGYYVKSYKLEVSTNGEDWMVYRHG--KNHKVFQANNDATEVVLNKLHAPLLTRFVR 408
Query: 431 VNPTQWQQKIAMKMELLGCQ 450
+ P W IA+++EL GC+
Sbjct: 409 IRPQTWHSGIALRLELFGCR 428
Score = 99.4 bits (246), Expect = 1e-20
Identities = 62/171 (36%), Positives = 89/171 (52%), Gaps = 21/171 (12%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPW---AAFATDEY 348
C LGM SG+IAD QI+ASS QE W P ARL W A
Sbjct: 434 CSNMLGMLSGLIADSQISASST--------QEYLWSPSAARLVSSRSGWFPRIPQAQPGE 485
Query: 349 QWLQIDLNKEKKITGIITTGS------TMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQ 402
+WLQ+DL K + G+I G+ T VE +V +++ YS +G+ W ++P +Q
Sbjct: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQ 545
Query: 403 DKIFQGNKDYH-QDVRNNFLPPIIARFIRVNPTQWQQK-IAMKMELLGCQF 451
K+F+GN Y D+R PI A+++RV P +W I M++E+LGC +
Sbjct: 546 PKLFEGNMHYDTPDIRR--FDPIPAQYVRVYPERWSPAGIGMRLEVLGCDW 594
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 128 bits (321), Expect = 2e-29
Identities = 112/440 (25%), Positives = 190/440 (43%), Gaps = 62/440 (14%)
Query: 53 LLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRV-KMGERV 111
+ L L Q CG + ++G +TS YPQ YP+ CEW + + +++
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 112 RIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCG-------------LGLQMNHS 157
+ F F+IE D C ++++ I +G S +GK+CG L ++
Sbjct: 69 VLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 158 IESKGNEITL---LFMSGIHVSGRGFLA--------------------SYSVIDKQDLIT 194
+G +L +F +G + F + +++++ K +
Sbjct: 128 YARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEI 187
Query: 195 CLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQI 254
L LE + + C + +I IPH C + + S+T G +
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSST--GIL 245
Query: 255 SVVISKGIPYYESSLANNVTSVVGHL--STSLFTFKTSGCYGTLGMESGVIADPQITASS 312
S+ + + ++A + S +L L F+ C LGMESG IA+ QI+ASS
Sbjct: 246 SLTF-----HTDMAVAKDGFSARYYLVHQEPLENFQ---CNVPLGMESGRIANEQISASS 297
Query: 313 VLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG--ST 370
T + W P+++RL W ++LQ+DL +T I T G S
Sbjct: 298 -------TYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISR 350
Query: 371 MVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIR 430
++ YYV +Y++ S +G+ W VYR + K+FQ N D + V N P++ RF+R
Sbjct: 351 ETQNGYYVKSYKLEVSTNGEDWMVYRHG--KNHKVFQANNDATEVVLNKLHAPLLTRFVR 408
Query: 431 VNPTQWQQKIAMKMELLGCQ 450
+ P W IA+++EL GC+
Sbjct: 409 IRPQTWHSGIALRLELFGCR 428
Score = 99.4 bits (246), Expect = 1e-20
Identities = 62/171 (36%), Positives = 89/171 (52%), Gaps = 21/171 (12%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPW---AAFATDEY 348
C LGM SG+IAD QI+ASS QE W P ARL W A
Sbjct: 434 CSNMLGMLSGLIADSQISASST--------QEYLWSPSAARLVSSRSGWFPRIPQAQPGE 485
Query: 349 QWLQIDLNKEKKITGIITTGS------TMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQ 402
+WLQ+DL K + G+I G+ T VE +V +++ YS +G+ W ++P +Q
Sbjct: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQ 545
Query: 403 DKIFQGNKDYH-QDVRNNFLPPIIARFIRVNPTQWQQK-IAMKMELLGCQF 451
K+F+GN Y D+R PI A+++RV P +W I M++E+LGC +
Sbjct: 546 PKLFEGNMHYDTPDIRR--FDPIPAQYVRVYPERWSPAGIGMRLEVLGCDW 594
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 128 bits (321), Expect = 2e-29
Identities = 112/440 (25%), Positives = 190/440 (43%), Gaps = 62/440 (14%)
Query: 53 LLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRV-KMGERV 111
+ L L Q CG + ++G +TS YPQ YP+ CEW + + +++
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 112 RIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCG-------------LGLQMNHS 157
+ F F+IE D C ++++ I +G S +GK+CG L ++
Sbjct: 69 VLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 158 IESKGNEITL---LFMSGIHVSGRGFLA--------------------SYSVIDKQDLIT 194
+G +L +F +G + F + +++++ K +
Sbjct: 128 YARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEI 187
Query: 195 CLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQI 254
L LE + + C + +I IPH C + + S+T G +
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSST--GIL 245
Query: 255 SVVISKGIPYYESSLANNVTSVVGHL--STSLFTFKTSGCYGTLGMESGVIADPQITASS 312
S+ + + ++A + S +L L F+ C LGMESG IA+ QI+ASS
Sbjct: 246 SLTF-----HTDMAVAKDGFSARYYLVHQEPLENFQ---CNVPLGMESGRIANEQISASS 297
Query: 313 VLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG--ST 370
T + W P+++RL W ++LQ+DL +T I T G S
Sbjct: 298 -------TYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISR 350
Query: 371 MVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIR 430
++ YYV +Y++ S +G+ W VYR + K+FQ N D + V N P++ RF+R
Sbjct: 351 ETQNGYYVKSYKLEVSTNGEDWMVYRHG--KNHKVFQANNDATEVVLNKLHAPLLTRFVR 408
Query: 431 VNPTQWQQKIAMKMELLGCQ 450
+ P W IA+++EL GC+
Sbjct: 409 IRPQTWHSGIALRLELFGCR 428
Score = 68.9 bits (167), Expect = 2e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 17/123 (13%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPW---AAFATDEY 348
C LGM SG+IAD QI+ASS QE W P ARL W A
Sbjct: 434 CSNMLGMLSGLIADSQISASST--------QEYLWSPSAARLVSSRSGWFPRIPQAQPGE 485
Query: 349 QWLQIDLNKEKKITGIITTGS------TMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQ 402
+WLQ+DL K + G+I G+ T VE +V +++ YS +G+ W ++P +Q
Sbjct: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQ 545
Query: 403 DKI 405
K+
Sbjct: 546 PKV 548
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 128 bits (321), Expect = 2e-29
Identities = 112/440 (25%), Positives = 190/440 (43%), Gaps = 62/440 (14%)
Query: 53 LLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRV-KMGERV 111
+ L L Q CG + ++G +TS YPQ YP+ CEW + + +++
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 112 RIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCG-------------LGLQMNHS 157
+ F F+IE D C ++++ I +G S +GK+CG L ++
Sbjct: 69 VLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 158 IESKGNEITL---LFMSGIHVSGRGFLA--------------------SYSVIDKQDLIT 194
+G +L +F +G + F + +++++ K +
Sbjct: 128 YARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEI 187
Query: 195 CLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQI 254
L LE + + C + +I IPH C + + S+T G +
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSST--GIL 245
Query: 255 SVVISKGIPYYESSLANNVTSVVGHL--STSLFTFKTSGCYGTLGMESGVIADPQITASS 312
S+ + + ++A + S +L L F+ C LGMESG IA+ QI+ASS
Sbjct: 246 SLTF-----HTDMAVAKDGFSARYYLVHQEPLENFQ---CNVPLGMESGRIANEQISASS 297
Query: 313 VLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG--ST 370
T + W P+++RL W ++LQ+DL +T I T G S
Sbjct: 298 -------TYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISR 350
Query: 371 MVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIR 430
++ YYV +Y++ S +G+ W VYR + K+FQ N D + V N P++ RF+R
Sbjct: 351 ETQNGYYVKSYKLEVSTNGEDWMVYRHG--KNHKVFQANNDATEVVLNKLHAPLLTRFVR 408
Query: 431 VNPTQWQQKIAMKMELLGCQ 450
+ P W IA+++EL GC+
Sbjct: 409 IRPQTWHSGIALRLELFGCR 428
Score = 99.4 bits (246), Expect = 1e-20
Identities = 62/171 (36%), Positives = 89/171 (52%), Gaps = 21/171 (12%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPW---AAFATDEY 348
C LGM SG+IAD QI+ASS QE W P ARL W A
Sbjct: 434 CSNMLGMLSGLIADSQISASST--------QEYLWSPSAARLVSSRSGWFPRIPQAQPGE 485
Query: 349 QWLQIDLNKEKKITGIITTGS------TMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQ 402
+WLQ+DL K + G+I G+ T VE +V +++ YS +G+ W ++P +Q
Sbjct: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQ 545
Query: 403 DKIFQGNKDYH-QDVRNNFLPPIIARFIRVNPTQWQQK-IAMKMELLGCQF 451
K+F+GN Y D+R PI A+++RV P +W I M++E+LGC +
Sbjct: 546 PKLFEGNMHYDTPDIRR--FDPIPAQYVRVYPERWSPAGIGMRLEVLGCDW 594
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 128 bits (321), Expect = 2e-29
Identities = 112/440 (25%), Positives = 190/440 (43%), Gaps = 62/440 (14%)
Query: 53 LLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRV-KMGERV 111
+ L L Q CG + ++G +TS YPQ YP+ CEW + + +++
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 112 RIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCG-------------LGLQMNHS 157
+ F F+IE D C ++++ I +G S +GK+CG L ++
Sbjct: 69 VLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 158 IESKGNEITL---LFMSGIHVSGRGFLA--------------------SYSVIDKQDLIT 194
+G +L +F +G + F + +++++ K +
Sbjct: 128 YARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEI 187
Query: 195 CLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQI 254
L LE + + C + +I IPH C + + S+T G +
Sbjct: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSST--GIL 245
Query: 255 SVVISKGIPYYESSLANNVTSVVGHL--STSLFTFKTSGCYGTLGMESGVIADPQITASS 312
S+ + + ++A + S +L L F+ C LGMESG IA+ QI+ASS
Sbjct: 246 SLTF-----HTDMAVAKDGFSARYYLVHQEPLENFQ---CNVPLGMESGRIANEQISASS 297
Query: 313 VLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG--ST 370
T + W P+++RL W ++LQ+DL +T I T G S
Sbjct: 298 -------TYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISR 350
Query: 371 MVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIR 430
++ YYV +Y++ S +G+ W VYR + K+FQ N D + V N P++ RF+R
Sbjct: 351 ETQNGYYVKSYKLEVSTNGEDWMVYRHG--KNHKVFQANNDATEVVLNKLHAPLLTRFVR 408
Query: 431 VNPTQWQQKIAMKMELLGCQ 450
+ P W IA+++EL GC+
Sbjct: 409 IRPQTWHSGIALRLELFGCR 428
Score = 99.4 bits (246), Expect = 1e-20
Identities = 62/171 (36%), Positives = 89/171 (52%), Gaps = 21/171 (12%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPW---AAFATDEY 348
C LGM SG+IAD QI+ASS QE W P ARL W A
Sbjct: 434 CSNMLGMLSGLIADSQISASST--------QEYLWSPSAARLVSSRSGWFPRIPQAQPGE 485
Query: 349 QWLQIDLNKEKKITGIITTGS------TMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQ 402
+WLQ+DL K + G+I G+ T VE +V +++ YS +G+ W ++P +Q
Sbjct: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQ 545
Query: 403 DKIFQGNKDYH-QDVRNNFLPPIIARFIRVNPTQWQQK-IAMKMELLGCQF 451
K+F+GN Y D+R PI A+++RV P +W I M++E+LGC +
Sbjct: 546 PKLFEGNMHYDTPDIRR--FDPIPAQYVRVYPERWSPAGIGMRLEVLGCDW 594
>gi|10518506 coagulation factor VIII isoform b precursor [Homo
sapiens]
Length = 216
Score = 120 bits (301), Expect = 5e-27
Identities = 66/178 (37%), Positives = 97/178 (54%), Gaps = 9/178 (5%)
Query: 275 SVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLK 334
S+ L L + C LGMES I+D QITASS T +W P KARL
Sbjct: 41 SIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYF-----TNMFATWSPSKARLH 95
Query: 335 KPGPP--WAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKW 392
G W + +WLQ+D K K+TG+ T G + + YV + I S DG +W
Sbjct: 96 LQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQW 155
Query: 393 TVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450
T++ + G + K+FQGN+D V N+ PP++ R++R++P W +IA++ME+LGC+
Sbjct: 156 TLFFQNG--KVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/54 (44%), Positives = 35/54 (64%), Gaps = 4/54 (7%)
Query: 396 REPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449
++PG K+F GN D N F PPIIAR+IR++PT + + ++MEL+GC
Sbjct: 4 QDPG----KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGC 53
>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
Length = 2351
Score = 120 bits (301), Expect = 5e-27
Identities = 66/178 (37%), Positives = 97/178 (54%), Gaps = 9/178 (5%)
Query: 275 SVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLK 334
S+ L L + C LGMES I+D QITASS T +W P KARL
Sbjct: 2176 SIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYF-----TNMFATWSPSKARLH 2230
Query: 335 KPGPP--WAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKW 392
G W + +WLQ+D K K+TG+ T G + + YV + I S DG +W
Sbjct: 2231 LQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQW 2290
Query: 393 TVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450
T++ + G + K+FQGN+D V N+ PP++ R++R++P W +IA++ME+LGC+
Sbjct: 2291 TLFFQNG--KVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 2346
Score = 109 bits (273), Expect = 8e-24
Identities = 65/168 (38%), Positives = 89/168 (52%), Gaps = 9/168 (5%)
Query: 282 TSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWA 341
++LF ++ C LGM SG I D QITAS GQ W PK ARL G A
Sbjct: 2030 STLFLVYSNKCQTPLGMASGHIRDFQITAS---------GQYGQWAPKLARLHYSGSINA 2080
Query: 342 AFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVE 401
+ + W+++DL I GI T G+ + Y+S + I+YS DG+KW YR
Sbjct: 2081 WSTKEPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTG 2140
Query: 402 QDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449
+F GN D N F PPIIAR+IR++PT + + ++MEL+GC
Sbjct: 2141 TLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGC 2188
>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
sapiens]
Length = 224
Score = 102 bits (253), Expect = 2e-21
Identities = 62/171 (36%), Positives = 91/171 (53%), Gaps = 7/171 (4%)
Query: 281 STSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPG--P 338
+TSL + LG ESG + QIT S+ ++ G +SW KARL G
Sbjct: 54 ATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYV---GWYSSWTANKARLNSQGFGC 110
Query: 339 PWAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREP 398
W + D QWLQIDL + K I+GI+T G ++ +++ Y + Y D + +Y +
Sbjct: 111 AWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDE--WMTKYSVQYRTDERLNWIYYKD 168
Query: 399 GVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449
+++F GN D V+N PPII+RFIR+ P W +IA++MELL C
Sbjct: 169 QTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLEC 219
>gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Homo
sapiens]
Length = 335
Score = 86.7 bits (213), Expect = 8e-17
Identities = 50/161 (31%), Positives = 90/161 (55%), Gaps = 6/161 (3%)
Query: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGP--PWAAFATDEYQ 349
C LG+E+G IA+ QI ASSV G ++ W P+ ARL + G W + D+
Sbjct: 70 CVEPLGLENGNIANSQIAASSVR--VTFLGLQH-WVPELARLNRAGMVNAWTPSSNDDNP 126
Query: 350 WLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGN 409
W+Q++L + +TG++T G++ + + Y+ A+++ YS +G ++ + ++ K F GN
Sbjct: 127 WIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVN-KKHKEFVGN 185
Query: 410 KDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450
+ + N F P+ A+++R+ PT ++ ELLGC+
Sbjct: 186 WNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226
Score = 67.8 bits (164), Expect = 4e-11
Identities = 52/173 (30%), Positives = 68/173 (39%), Gaps = 58/173 (33%)
Query: 280 LSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLE-WTDHTGQENSWKPKKARLKKPGP 338
L L + +GC LG+++ I D QITASS + W H SW P ARL K G
Sbjct: 218 LRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLF---SWNPSYARLDKQGN 274
Query: 339 --PWAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYR 396
W A + QWLQ
Sbjct: 275 FNAWVAGSYGNDQWLQ-------------------------------------------- 290
Query: 397 EPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449
IF GN D H +N F PI+AR++R+ P W +IA+++ELLGC
Sbjct: 291 --------IFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 85.9 bits (211), Expect = 1e-16
Identities = 53/160 (33%), Positives = 79/160 (49%), Gaps = 5/160 (3%)
Query: 296 LGMESGVIADPQITASSVLEWT--DHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQI 353
+GMES I D QI ASS+L G+ N G W A QW+++
Sbjct: 388 IGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGA-WCAEDDARTQWIEV 446
Query: 354 DLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYH 413
D + + TG+IT G H+ +V+ + + +S+D Q W +Y G E+ F GN D
Sbjct: 447 DTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTN-GYEE-MTFHGNVDKD 504
Query: 414 QDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQFIP 453
V + P++ARFIR+ P W + M++E+LGC P
Sbjct: 505 TPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAP 544
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
sapiens]
Length = 1331
Score = 85.1 bits (209), Expect = 2e-16
Identities = 47/151 (31%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 305 DPQITASSVLEWTDHTGQENSWKPKKARLKKPGPP--WAAFATDEYQWLQIDLNKEKKIT 362
+P ++ + ++ + S+ P A++ K G W+ +D YQWLQ+D K+I+
Sbjct: 37 EPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQIS 96
Query: 363 GIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLP 422
I T G + +V+ YR+LYSD G+ W Y + G F GN + VR+
Sbjct: 97 AIATQG--RYSSSDWVTQYRMLYSDTGRNWKPYHQDG--NIWAFPGNINSDGVVRHELQH 152
Query: 423 PIIARFIRVNPTQW--QQKIAMKMELLGCQF 451
PIIAR++R+ P W + +I +++E+ GC +
Sbjct: 153 PIIARYVRIVPLDWNGEGRIGLRIEVYGCSY 183
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 84.3 bits (207), Expect = 4e-16
Identities = 51/158 (32%), Positives = 81/158 (51%), Gaps = 7/158 (4%)
Query: 296 LGMESGVIADPQITASSVLEWT--DHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQI 353
LG+E+ I D Q+ AS+V + H G+ N G W A D QW+++
Sbjct: 139 LGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGA-WCAGRNDLQQWIEV 197
Query: 354 DLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYH 413
D + + TG+IT G + + +V++Y+++ S+D W + D IF+GN +
Sbjct: 198 DARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNG--SGDMIFEGNSEKE 255
Query: 414 QDVRNNFLPPIIARFIRVNPTQW--QQKIAMKMELLGC 449
V N P++AR+IR+NP W I M+ME+LGC
Sbjct: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 82.8 bits (203), Expect = 1e-15
Identities = 49/145 (33%), Positives = 74/145 (51%), Gaps = 7/145 (4%)
Query: 68 QGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCH 127
Q D CG + G SG LTS YP YPNS C W IR V++ F DF +E ++ C
Sbjct: 141 QKDVCGGVLTGL-SGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECT 199
Query: 128 FNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVI 187
++Y+ + G G +R YC G ++ S G+E+ ++F S ++ GRGF A Y
Sbjct: 200 YDYVAVLGGPGPTRGH--HYC--GSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSG 255
Query: 188 DKQDLITCLDTASNFLEPEFSKYCP 212
+ Q++ + NF P++ P
Sbjct: 256 ECQEVYMAM--RGNFSSPQYPSSYP 278
Score = 79.3 bits (194), Expect = 1e-14
Identities = 49/135 (36%), Positives = 71/135 (52%), Gaps = 4/135 (2%)
Query: 51 LLLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGER 110
LLL + LL A A +G CG + P SG +S N+P+ YP +T C W I V G
Sbjct: 9 LLLAVALLGPGLQAQAMEGVKCGGVLSAP-SGNFSSPNFPRLYPYNTECSWLIVVAEGSS 67
Query: 111 VRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTE-IGKYCGLGLQMNHSIESKGNEITLLF 169
V + F FD+E D+C F++L IYNG + +G++C G S + ++++F
Sbjct: 68 VLLTFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFC--GKVPPPPFTSSWHVMSVIF 125
Query: 170 MSGIHVSGRGFLASY 184
S HV+ GF A Y
Sbjct: 126 HSDKHVASHGFSAGY 140
Score = 63.9 bits (154), Expect = 5e-10
Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 6/107 (5%)
Query: 82 GTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDS----CHFNYLRIYNGI 137
G +S YP +YPN+ C W IR+ G +V++ F D D+E+ +S C F++L ++G
Sbjct: 266 GNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGA 325
Query: 138 GVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
+G +CG L + S N++ LL + + RGF +Y
Sbjct: 326 SEEAPLLGNWCGHHLP--PPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
sapiens]
Length = 1308
Score = 79.7 bits (195), Expect = 9e-15
Identities = 54/183 (29%), Positives = 87/183 (47%), Gaps = 12/183 (6%)
Query: 275 SVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLK 334
SV G + +L T S DP ++A ++ + +S P ARL
Sbjct: 3 SVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLN 62
Query: 335 KPGPP--WAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKW 392
+ W+ +++YQWLQIDL + ++T + T G + +V++Y +++SD G W
Sbjct: 63 RRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGG--YGSSNWVTSYLLMFSDSGWNW 120
Query: 393 TVYREPGVEQDKI--FQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQK--IAMKMELLG 448
YR ++D I F GN + V P I ARF+R P +W K I M++E+ G
Sbjct: 121 KQYR----QEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFG 176
Query: 449 CQF 451
C +
Sbjct: 177 CAY 179
>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
sapiens]
Length = 1235
Score = 79.0 bits (193), Expect = 2e-14
Identities = 48/153 (31%), Positives = 79/153 (51%), Gaps = 12/153 (7%)
Query: 305 DPQITASSVLEWTDHTGQENSWKPKKARLKKPGPP--WAAFATDEYQWLQIDLNKEKKIT 362
DP ++A ++ + +S P ARL + W+ +++YQWLQIDL + ++T
Sbjct: 8 DPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVT 67
Query: 363 GIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKI--FQGNKDYHQDVRNNF 420
+ T G + +V++Y +++SD G W YR ++D I F GN + V
Sbjct: 68 AVATQGG--YGSSNWVTSYLLMFSDSGWNWKQYR----QEDSIWGFSGNANADSVVYYRL 121
Query: 421 LPPIIARFIRVNPTQWQQK--IAMKMELLGCQF 451
P I ARF+R P +W K I M++E+ GC +
Sbjct: 122 QPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAY 154
>gi|26051243 tumor necrosis factor, alpha-induced protein 6
precursor [Homo sapiens]
Length = 277
Score = 78.2 bits (191), Expect = 3e-14
Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 3/117 (2%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG P+ S +P Y ++ +C W IR+K G+R+ + F DFD+ED C +Y+
Sbjct: 135 CGGVFTDPKQ-IFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVID 188
IY+ +G+YC G ++ I S GN +TL F+S V+ GF Y +D
Sbjct: 194 EIYDSYDDVHGFVGRYC--GDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD 248
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 77.8 bits (190), Expect = 4e-14
Identities = 44/114 (38%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 71 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 130
GCG P SG + S NYP Y ++T C W IRV RV + F DFD+E DSC
Sbjct: 1509 GCGGIFQAP-SGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC---- 1563
Query: 131 LRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
+ Y+G+ + + + + CG Q+ + I S GN + L F SG RGF A +
Sbjct: 1564 IMAYDGLSSTMSRLARTCGRE-QLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 75.1 bits (183), Expect = 2e-13
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 19/160 (11%)
Query: 37 PPCSNSSSFSMPLFLLLLLVLLLLLEDAGAQQGD--------GCGHTVLGPESGTLTSIN 88
PP S +SS L +LLL + G ++ GCG + G +G+ +S
Sbjct: 1357 PPGSTTSS---------KLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGA-TGSFSSPG 1406
Query: 89 YPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYC 148
+P YP + C W IR G +++ DFD+E C+F+ L IY G I + C
Sbjct: 1407 FPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLC 1466
Query: 149 GLGLQMN-HSIESKGNEITLLFMSGIHVSGRGFLASYSVI 187
N + S GNE+ + F + + ++GRGF AS+ +
Sbjct: 1467 TQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506
Score = 73.6 bits (179), Expect = 7e-13
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Query: 82 GTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSR 141
G + S +P+ YP+++ +W + V V + + DIE+ +C+++ LRIY+G +
Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHA 1920
Query: 142 TEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVIDKQD 191
IG YCG S S GN +T F S +SG+GFL + +D D
Sbjct: 1921 RLIGAYCG---TQTESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPD 1967
Score = 71.6 bits (174), Expect = 3e-12
Identities = 35/79 (44%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 71 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 130
GCG T+ G + G+ TS YP TYPN+T CEW + G V I F I+D C NY
Sbjct: 3510 GCGGTLYG-DRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNY 3568
Query: 131 LRIYNGIGVSRTEIGKYCG 149
L +Y+G S G YCG
Sbjct: 3569 LTLYDGPNASSPSSGPYCG 3587
Score = 71.2 bits (173), Expect = 3e-12
Identities = 44/145 (30%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG +L +GT+ S +P YP+ C W I V+ + + F F +E +C +YL
Sbjct: 932 CGE-ILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYL 990
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVIDKQD 191
+Y+ S T +G+YCG + S+ S GN + L+F++ ++ GFL +Y I
Sbjct: 991 EVYD--TDSETSLGRYCGKSIP--PSLTSSGNSLMLVFVTDSDLAYEGFLINYEAISA-- 1044
Query: 192 LITCL----DTASNFLEPEFSKYCP 212
CL D F P F P
Sbjct: 1045 ATACLQDYTDDLGTFTSPNFPNNYP 1069
Score = 68.6 bits (166), Expect = 2e-11
Identities = 35/114 (30%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG + G GT TS NYP P+ +CEW I G R+ + F + + SC+ ++
Sbjct: 2452 CGGDLQG-SIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHV 2510
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYS 185
++NGI + ++ K C + +++ I+S GN + ++F + GF ASY+
Sbjct: 2511 IVFNGIRSNSPQLEKLCS-SVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYT 2563
Score = 67.8 bits (164), Expect = 4e-11
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG +G +SG +TS NYP Y + T C + G + + F DFDIE +C ++ +
Sbjct: 2689 CGGIQIG-DSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSV 2747
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYS 185
+ NG IG+YC G +I+S N++ + F S + G GF A+++
Sbjct: 2748 TVRNGGSPESPIIGQYC--GNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWN 2799
Score = 64.7 bits (156), Expect = 3e-10
Identities = 40/122 (32%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG T E G S YP YP + C W I G R+++ F F +EDS C +++
Sbjct: 1738 CGGTFYMAE-GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFV 1796
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVIDKQD 191
I G +G+YCG +N+S G+ + + F+S SG GF A++ I D
Sbjct: 1797 EIREGNATGHL-VGRYCGNSFPLNYS-SIVGHTLWVRFISDGSGSGTGFQATFMKIFGND 1854
Query: 192 LI 193
I
Sbjct: 1855 NI 1856
Score = 64.3 bits (155), Expect = 4e-10
Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 4/114 (3%)
Query: 72 CGHTVLGPESGTLTSINYPQT-YPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 130
CG V SG +TS Y YPN C + I V + + +KF DFD+ S SC +Y
Sbjct: 3037 CGG-VFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095
Query: 131 LRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
L IY+G S +GK+CG N ++S N + L+F + + +G+ S+
Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPN--VKSSNNSMLLVFKTDSFQTAKGWKMSF 3147
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/159 (31%), Positives = 70/159 (44%), Gaps = 24/159 (15%)
Query: 37 PPCSNSSSFSMPLFLLLLLVLLLLLEDAGAQQGDG--------CGHTVLGPES-GTLTSI 87
PP SS SM + L D G QQG G C + V+ ++ G L SI
Sbjct: 1245 PPLIRSSGDSM---------FIKLRTDEG-QQGRGFKAEYRQTCENVVIVNQTYGILESI 1294
Query: 88 NYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKY 147
YP Y + C W IR G V F FD+E +C +YL +Y+G ++G+Y
Sbjct: 1295 GYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG----PRQMGRY 1350
Query: 148 CGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSV 186
CG+ L S S ++ LL G+ +GF + V
Sbjct: 1351 CGVDLPPPGSTTSSKLQV-LLLTDGVGRREKGFQMQWFV 1388
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 71 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 130
GCG L SGT S NYP Y +S+ C W ++ G ++F DF +E +C +Y
Sbjct: 1164 GCGGN-LTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDY 1222
Query: 131 LRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
L +Y+G + + + C G + I S G+ + + + GRGF A Y
Sbjct: 1223 LAVYDGPSSNSHLLTQLC--GDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Score = 61.2 bits (147), Expect = 3e-09
Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
Query: 66 AQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMG-ERVRIKFGDFDIEDSD 124
AQ CG +L T++S +P YPN+ C W I+ + + + F F++E S
Sbjct: 1614 AQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERST 1673
Query: 125 SCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF 180
+C +++ I +G G+YC G M H I S + +TL F+S +S GF
Sbjct: 1674 TCARDFVEILDGGHEDAPLRGRYC--GTDMPHPITSFSSALTLRFVSDSSISAGGF 1727
Score = 60.1 bits (144), Expect = 8e-09
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 72 CGHTVL---GPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGD-FDIEDSDSCH 127
CG V +G +TS N+P YP C W + R++++F D FDIE + +C
Sbjct: 2217 CGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCT 2276
Query: 128 FNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSV 186
NYL + +G+ + K+CG L S S G + L F S + GF A YS+
Sbjct: 2277 SNYLELRDGVDSDAPILSKFCGTSLP--SSQWSSGEVMYLRFRSDNSPTHVGFKAKYSI 2333
Score = 57.4 bits (137), Expect = 5e-08
Identities = 33/109 (30%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG ++ G +G+ + + Y + C W I+ +MG+ +RI F F +E D+C +L
Sbjct: 474 CGESLSGI-NGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFL 532
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF 180
++Y+G S ++G++CG L H + S N + S +GRGF
Sbjct: 533 QVYDGDSSSAFQLGRFCGSSLP--HELLSSDNALYFHLYSEHLRNGRGF 579
Score = 55.5 bits (132), Expect = 2e-07
Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Query: 72 CGHTVLGPESGTLTSINYPQT-YPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 130
CG V G +SG + SI +P Y ++ CEW ++ G + I F DF++++S C ++
Sbjct: 2336 CGGRVPG-QSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDF 2394
Query: 131 LRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF 180
+ I++ S +G+YCG + SI++ N + F++ V+ GF
Sbjct: 2395 VEIWDN-HTSGNILGRYCGNTIP--DSIDTSSNTAVVRFVTDGSVTASGF 2441
Score = 53.1 bits (126), Expect = 9e-07
Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 4/117 (3%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG + G G + S +P YP C W I + + + F F+I S C +Y+
Sbjct: 817 CGDELTG--EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYV 874
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVID 188
I + + E KYCG + I S N + + F+ GF+A +S D
Sbjct: 875 EIGSSSILGSPENKKYCGTDIP--SFITSVYNFLYVTFVKSSSTENHGFMAKFSAED 929
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 16/157 (10%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG + GP G++ S YP YP C W + V FG +E D C+ +YL
Sbjct: 590 CGGILTGPY-GSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYL 648
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVIDKQD 191
I +G +GK+C +++ G + F S +S +GF +Y
Sbjct: 649 EIRDGPLYQDPLLGKFC--TTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSD- 705
Query: 192 LITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPH 228
L N+ +PE + P E+SG H
Sbjct: 706 ----LRCGGNYTDPEGELFLP--------ELSGPFTH 730
Score = 51.6 bits (122), Expect = 3e-06
Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Query: 82 GTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSR 141
G L S +P Y N C + + + F IE+S C ++L + NG +
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNS 3463
Query: 142 TEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF 180
+GKYCG L + + S+ NE+ L F S S RG+
Sbjct: 3464 PLLGKYCGTLLP--NPVFSQNNELYLRFKSDSVTSDRGY 3500
Score = 49.3 bits (116), Expect = 1e-05
Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 77 LGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGD-FDIEDSDSC--HFNYLRI 133
L + G +TS YP+TYP++ C W + V+ G + + F F I + DS +YL +
Sbjct: 2096 LHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVL 2155
Query: 134 YNGIGVSRTEIGKYCG----LGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
NG + +G G G + ++ + N++ + F+S G+GF Y
Sbjct: 2156 RNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 10/129 (7%)
Query: 65 GAQQGDGCGHTVLGPESGTLTSINYPQT--YPNSTVCEWEIRVKMGERVRIKFGDFDIED 122
G QQG CG + G + T S + Y + C W I + + + + F F +E
Sbjct: 3152 GPQQG--CGGYLTG-SNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEA 3208
Query: 123 SDS---CHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRG 179
+ + C ++Y+++Y+G + G +CG + S GN +T+ F+S + + G
Sbjct: 3209 ASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPA--PFISSGNFLTVQFISDLTLEREG 3266
Query: 180 FLASYSVID 188
F A+Y+++D
Sbjct: 3267 FNATYTIMD 3275
Score = 47.0 bits (110), Expect = 7e-05
Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 3/102 (2%)
Query: 82 GTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHF-NYLRIYNGIGVS 140
GT TS N+P YPN+ C + I V+ G+ + + F +F +E++ ++ ++L I +G
Sbjct: 1057 GTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEK 1116
Query: 141 RTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLA 182
+G + G L +I S N++ L F S + GF A
Sbjct: 1117 SPLLGIFYGSNLP--PTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 43.9 bits (102), Expect = 6e-04
Identities = 35/120 (29%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIED----SDSCH 127
CG GP SG + S NYP+ Y N+ C + I V + F F +E + SC
Sbjct: 2920 CGSNFTGP-SGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCV 2978
Query: 128 FNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVI 187
+ + I G V T CG + +I + L F S ++ GF SY +I
Sbjct: 2979 NDGVHIIRGYSVMSTPFATVCGDEMPAPLTI---AGPVLLNFYSNEQITDFGFKFSYRII 3035
Score = 38.9 bits (89), Expect = 0.018
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 7/115 (6%)
Query: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
CG PE G L + ++ C + ++ GE+++I F +++ NY+
Sbjct: 708 CGGNYTDPE-GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYI 766
Query: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSV 186
+ +G T +GK CG G ++H I+S N + + F V F A Y V
Sbjct: 767 EVRDG----ETLLGKVCGNG-TISH-IKSITNSVWIRFKIDASVEKASFRAVYQV 815
Score = 38.1 bits (87), Expect = 0.031
Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
Query: 84 LTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTE 143
L S +P +Y N C W I+ V + DIE +C ++ L I +G +
Sbjct: 1991 LFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQ 2049
Query: 144 IGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
+ C G ++ I S G + + F S V+ GF AS+
Sbjct: 2050 LAVLC--GREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088
Score = 38.1 bits (87), Expect = 0.031
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 11/119 (9%)
Query: 71 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKF-GDFDIEDSD-SCHF 128
GCG + ++GT+ S ++PQ +P ++ C W + + I F +F I D C
Sbjct: 2804 GCGG-IFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQN 2862
Query: 129 NYLRIYNGIGVSRTEIGK---YCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
++++++ G E+ K G G + + N T +F S +GF AS+
Sbjct: 2863 SFVKVWAG----TEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASF 2916
>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
sapiens]
Length = 1221
Score = 76.6 bits (187), Expect = 8e-14
Identities = 46/116 (39%), Positives = 62/116 (53%), Gaps = 8/116 (6%)
Query: 71 GCGH--TVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHF 128
GC + VL SGT TS YP YPNS C W +R G ++I F DFDIE++ +C +
Sbjct: 37 GCANCRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIY 96
Query: 129 NYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
+ L + N G S+T K+CG S S NE+ + F S + +GF ASY
Sbjct: 97 DSLSLDN--GESQT---KFCG-ATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
sapiens]
Length = 1250
Score = 76.6 bits (187), Expect = 8e-14
Identities = 46/116 (39%), Positives = 62/116 (53%), Gaps = 8/116 (6%)
Query: 71 GCGH--TVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHF 128
GC + VL SGT TS YP YPNS C W +R G ++I F DFDIE++ +C +
Sbjct: 37 GCANCRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIY 96
Query: 129 NYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
+ L + N G S+T K+CG S S NE+ + F S + +GF ASY
Sbjct: 97 DSLSLDN--GESQT---KFCG-ATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
sapiens]
Length = 1193
Score = 76.6 bits (187), Expect = 8e-14
Identities = 46/116 (39%), Positives = 62/116 (53%), Gaps = 8/116 (6%)
Query: 71 GCGH--TVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHF 128
GC + VL SGT TS YP YPNS C W +R G ++I F DFDIE++ +C +
Sbjct: 37 GCANCRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIY 96
Query: 129 NYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
+ L + N G S+T K+CG S S NE+ + F S + +GF ASY
Sbjct: 97 DSLSLDN--GESQT---KFCG-ATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
sapiens]
Length = 1222
Score = 76.6 bits (187), Expect = 8e-14
Identities = 46/116 (39%), Positives = 62/116 (53%), Gaps = 8/116 (6%)
Query: 71 GCGH--TVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHF 128
GC + VL SGT TS YP YPNS C W +R G ++I F DFDIE++ +C +
Sbjct: 37 GCANCRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIY 96
Query: 129 NYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
+ L + N G S+T K+CG S S NE+ + F S + +GF ASY
Sbjct: 97 DSLSLDN--GESQT---KFCG-ATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,649,018
Number of Sequences: 37866
Number of extensions: 1731922
Number of successful extensions: 7313
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 6513
Number of HSP's gapped (non-prelim): 637
length of query: 775
length of database: 18,247,518
effective HSP length: 110
effective length of query: 665
effective length of database: 14,082,258
effective search space: 9364701570
effective search space used: 9364701570
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.