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Search of human proteins with 54792109
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens]
(466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|54792105 cholinergic receptor, muscarinic 2 [Homo sapiens] 944 0.0
gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens] 523 e-148
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] 408 e-114
gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] 391 e-109
gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens] 388 e-108
gi|149158709 histamine receptor H1 [Homo sapiens] 189 5e-48
gi|149158706 histamine receptor H1 [Homo sapiens] 189 5e-48
gi|149158704 histamine receptor H1 [Homo sapiens] 189 5e-48
gi|4504491 histamine receptor H1 [Homo sapiens] 189 5e-48
gi|194018562 histamine receptor H3 [Homo sapiens] 186 3e-47
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 173 3e-43
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens] 150 3e-36
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens] 149 5e-36
gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens] 149 7e-36
gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens] 137 2e-32
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] 136 5e-32
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 133 3e-31
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 133 3e-31
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 133 3e-31
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 133 3e-31
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 131 1e-30
gi|32483397 dopamine receptor D4 [Homo sapiens] 127 2e-29
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 125 6e-29
>gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792105 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 944 bits (2439), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
Sbjct: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Sbjct: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
Sbjct: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
Query: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
Sbjct: 241 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE 300
Query: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
Sbjct: 301 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI 360
Query: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
Sbjct: 361 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT 420
Query: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Sbjct: 421 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens]
Length = 479
Score = 523 bits (1347), Expect = e-148
Identities = 277/478 (57%), Positives = 344/478 (71%), Gaps = 25/478 (5%)
Query: 6 NSSNNSLALTSP-----YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
+S N S+ L + Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNY
Sbjct: 10 SSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNY 69
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
FLFSLACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFD
Sbjct: 70 FLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFD 129
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RYFCVTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF
Sbjct: 130 RYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQF 189
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI 240
SN AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ +
Sbjct: 190 LSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPL 249
Query: 241 VKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMR 297
+K + P + + L + K++ P P V +K++SN+S+S SA N +
Sbjct: 250 MKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTK 306
Query: 298 DDEITQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGS 349
+ T+ T +T+ + + S+ + I+I TK ++ T +E+V +
Sbjct: 307 ERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPA 362
Query: 350 SGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVL 408
+ N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL
Sbjct: 363 TPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVL 421
Query: 409 INTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
+NTFC CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 422 VNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
Length = 590
Score = 408 bits (1049), Expect = e-114
Identities = 223/499 (44%), Positives = 295/499 (59%), Gaps = 59/499 (11%)
Query: 18 YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77
+ ++VVFI + G L+LVTIIGNILV+VS KVN+ L+TVNNYFL SLACADLIIGV SM
Sbjct: 63 HTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISM 122
Query: 78 NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137
NL+T Y ++ W LG + CDLWLA+DYV SNASVMNLL+ISFDRYF +T+PLTY KRTT
Sbjct: 123 NLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTT 182
Query: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYL 197
K AG+MI AWV+SF+LWAPAILFWQ+ VG RTV GEC+IQF S +TFGTAIAAFY+
Sbjct: 183 KRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYM 242
Query: 198 PVIIMTVLYWHISRASKSRIK--------------KDKKEPVANQDPVSPSLVQGRIVKP 243
PV IMT+LYW I + ++ R K ++ P + S +Q + +K
Sbjct: 243 PVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKR 302
Query: 244 NNNN--------------MPSSDDGLEHNKIQNGKAPRDPVT--ENCVQGEEKESSNDST 287
+N PSS+ + + + D EN +E++ +++
Sbjct: 303 SNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETR 362
Query: 288 SVSAVASNM--------------RDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPK 333
++ ++ + D+ +E L D+ Q + G PK
Sbjct: 363 AIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPK 422
Query: 334 S--------DSCTPTNTTVEVVGSSGQNG-----DEKQNIVARKIVKMTKQPAKKKPPPS 380
S +S T T +V S G++ K+ +A++ T+ K+ S
Sbjct: 423 SFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMS 482
Query: 381 --REKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPA 438
+EKK +T+ AILLAFIITW PYN+MVL+NTFC CIP T W +GYWLCYINST+NP
Sbjct: 483 LVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVNPV 542
Query: 439 CYALCNATFKKTFKHLLMC 457
CYALCN TF+ TFK LL+C
Sbjct: 543 CYALCNKTFRTTFKMLLLC 561
>gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
Length = 460
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
Query: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
Query: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
Query: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
Query: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
Query: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
Query: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
Query: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
>gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens]
Length = 532
Score = 388 bits (997), Expect = e-108
Identities = 218/503 (43%), Positives = 278/503 (55%), Gaps = 72/503 (14%)
Query: 18 YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77
++ +EV+ I V +SL+TI+GN+LVM+S KVN L+TVNNY+L SLACADLIIG+FSM
Sbjct: 25 HRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSM 84
Query: 78 NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137
NLYT Y ++G W LG + CDLWLALDYV SNASVMNLL+ISFDRYF +T+PLTY KRT
Sbjct: 85 NLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTP 144
Query: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYL 197
K AG+MI AW++SFILWAPAIL WQ++VG RTV EC IQF S +TFGTAIAAFY+
Sbjct: 145 KRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYI 204
Query: 198 PVIIMTVLYWHISRASKSRIK-------KDKKEPVANQDPVSPSLVQGRIVKP------- 243
PV +MT+LY I R ++ R K D + P +L + + P
Sbjct: 205 PVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQR 264
Query: 244 --------------NNNNMPSSDDGLEHN---------------KIQNGKAPRDPVTENC 274
+ PS G N K DPV +
Sbjct: 265 ERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKPATDPVLQVV 324
Query: 275 VQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKS 334
+ + KES + S +E V S + PKS
Sbjct: 325 YKSQGKESPGEEFSAEET-----------EETFVKAETEKSDYDTPNYLLSPAAAHRPKS 373
Query: 335 DSCTPTNTTVEVVGSSGQ---NGDEKQNIVARKIVKMTKQPAKK--KPPPS--------- 380
C + V Q NG K I+ + K+P+ K P PS
Sbjct: 374 QKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPF-PVAKEPSTKGLNPNPSHQMTKRKRV 432
Query: 381 ---REKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINP 437
+E+K +T+ AILLAFIITW PYN+MVL++TFC C+P T+W +GYWLCY+NST+NP
Sbjct: 433 VLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNP 492
Query: 438 ACYALCNATFKKTFKHLLMCHYK 460
CYALCN TF+KTFK LL+C +K
Sbjct: 493 ICYALCNRTFRKTFKMLLLCRWK 515
>gi|149158709 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 189 bits (480), Expect = 5e-48
Identities = 137/475 (28%), Positives = 219/475 (46%), Gaps = 38/475 (8%)
Query: 10 NSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACAD 69
N + SP +++ +V+V ++ LVT+ N+LV+ +++ R L TV N ++ SL+ AD
Sbjct: 18 NKTTMASP----QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVAD 73
Query: 70 LIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPL 129
LI+G M + LY ++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL
Sbjct: 74 LIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPL 133
Query: 130 TYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV-EDGECYIQFFSNAAVTF 188
Y RT A I AW LSF LW IL W + +V + +C F+
Sbjct: 134 RYLKYRTKTRASATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKV 192
Query: 189 GTAIAAFYLPVIIMTVLYWHISRASKSRIKK----DKKEPVANQDPVSPSLVQGRIVKPN 244
TAI FYLP ++M Y I +A + + ++ P ++ + P +G KP
Sbjct: 193 MTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPG 252
Query: 245 NNN-------MPSSDDG--LEHNKIQNGKAPRDPVTENCVQGEE-------------KES 282
+ P G + + Q K + PV + E ++
Sbjct: 253 KESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQA 312
Query: 283 SNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNT 342
+ + +S VA N ++ DE ++T H E S+ + ++DS T T T
Sbjct: 313 AAEGSSRDYVAVNRSHGQLKTDEQGLNT---HGASEISEDQMLGDSQSFSRTDSDTTTET 369
Query: 343 T--VEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITW 400
+ S G + +++ ++Q +RE+K + + I+ AFI+ W
Sbjct: 370 APGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGL-HMNRERKAAKQLGFIMAAFILCW 428
Query: 401 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL 455
PY + ++ FC C + WL YINST+NP Y LCN FKKTFK +L
Sbjct: 429 IPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|149158706 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 189 bits (480), Expect = 5e-48
Identities = 137/475 (28%), Positives = 219/475 (46%), Gaps = 38/475 (8%)
Query: 10 NSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACAD 69
N + SP +++ +V+V ++ LVT+ N+LV+ +++ R L TV N ++ SL+ AD
Sbjct: 18 NKTTMASP----QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVAD 73
Query: 70 LIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPL 129
LI+G M + LY ++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL
Sbjct: 74 LIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPL 133
Query: 130 TYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV-EDGECYIQFFSNAAVTF 188
Y RT A I AW LSF LW IL W + +V + +C F+
Sbjct: 134 RYLKYRTKTRASATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKV 192
Query: 189 GTAIAAFYLPVIIMTVLYWHISRASKSRIKK----DKKEPVANQDPVSPSLVQGRIVKPN 244
TAI FYLP ++M Y I +A + + ++ P ++ + P +G KP
Sbjct: 193 MTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPG 252
Query: 245 NNN-------MPSSDDG--LEHNKIQNGKAPRDPVTENCVQGEE-------------KES 282
+ P G + + Q K + PV + E ++
Sbjct: 253 KESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQA 312
Query: 283 SNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNT 342
+ + +S VA N ++ DE ++T H E S+ + ++DS T T T
Sbjct: 313 AAEGSSRDYVAVNRSHGQLKTDEQGLNT---HGASEISEDQMLGDSQSFSRTDSDTTTET 369
Query: 343 T--VEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITW 400
+ S G + +++ ++Q +RE+K + + I+ AFI+ W
Sbjct: 370 APGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGL-HMNRERKAAKQLGFIMAAFILCW 428
Query: 401 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL 455
PY + ++ FC C + WL YINST+NP Y LCN FKKTFK +L
Sbjct: 429 IPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|149158704 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 189 bits (480), Expect = 5e-48
Identities = 137/475 (28%), Positives = 219/475 (46%), Gaps = 38/475 (8%)
Query: 10 NSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACAD 69
N + SP +++ +V+V ++ LVT+ N+LV+ +++ R L TV N ++ SL+ AD
Sbjct: 18 NKTTMASP----QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVAD 73
Query: 70 LIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPL 129
LI+G M + LY ++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL
Sbjct: 74 LIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPL 133
Query: 130 TYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV-EDGECYIQFFSNAAVTF 188
Y RT A I AW LSF LW IL W + +V + +C F+
Sbjct: 134 RYLKYRTKTRASATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKV 192
Query: 189 GTAIAAFYLPVIIMTVLYWHISRASKSRIKK----DKKEPVANQDPVSPSLVQGRIVKPN 244
TAI FYLP ++M Y I +A + + ++ P ++ + P +G KP
Sbjct: 193 MTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPG 252
Query: 245 NNN-------MPSSDDG--LEHNKIQNGKAPRDPVTENCVQGEE-------------KES 282
+ P G + + Q K + PV + E ++
Sbjct: 253 KESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQA 312
Query: 283 SNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNT 342
+ + +S VA N ++ DE ++T H E S+ + ++DS T T T
Sbjct: 313 AAEGSSRDYVAVNRSHGQLKTDEQGLNT---HGASEISEDQMLGDSQSFSRTDSDTTTET 369
Query: 343 T--VEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITW 400
+ S G + +++ ++Q +RE+K + + I+ AFI+ W
Sbjct: 370 APGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGL-HMNRERKAAKQLGFIMAAFILCW 428
Query: 401 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL 455
PY + ++ FC C + WL YINST+NP Y LCN FKKTFK +L
Sbjct: 429 IPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|4504491 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 189 bits (480), Expect = 5e-48
Identities = 137/475 (28%), Positives = 219/475 (46%), Gaps = 38/475 (8%)
Query: 10 NSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACAD 69
N + SP +++ +V+V ++ LVT+ N+LV+ +++ R L TV N ++ SL+ AD
Sbjct: 18 NKTTMASP----QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVAD 73
Query: 70 LIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPL 129
LI+G M + LY ++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL
Sbjct: 74 LIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPL 133
Query: 130 TYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV-EDGECYIQFFSNAAVTF 188
Y RT A I AW LSF LW IL W + +V + +C F+
Sbjct: 134 RYLKYRTKTRASATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKV 192
Query: 189 GTAIAAFYLPVIIMTVLYWHISRASKSRIKK----DKKEPVANQDPVSPSLVQGRIVKPN 244
TAI FYLP ++M Y I +A + + ++ P ++ + P +G KP
Sbjct: 193 MTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPG 252
Query: 245 NNN-------MPSSDDG--LEHNKIQNGKAPRDPVTENCVQGEE-------------KES 282
+ P G + + Q K + PV + E ++
Sbjct: 253 KESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQA 312
Query: 283 SNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNT 342
+ + +S VA N ++ DE ++T H E S+ + ++DS T T T
Sbjct: 313 AAEGSSRDYVAVNRSHGQLKTDEQGLNT---HGASEISEDQMLGDSQSFSRTDSDTTTET 369
Query: 343 T--VEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITW 400
+ S G + +++ ++Q +RE+K + + I+ AFI+ W
Sbjct: 370 APGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGL-HMNRERKAAKQLGFIMAAFILCW 428
Query: 401 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL 455
PY + ++ FC C + WL YINST+NP Y LCN FKKTFK +L
Sbjct: 429 IPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|194018562 histamine receptor H3 [Homo sapiens]
Length = 445
Score = 186 bits (473), Expect = 3e-47
Identities = 124/469 (26%), Positives = 221/469 (47%), Gaps = 68/469 (14%)
Query: 3 NSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLV---TIIGNILVMVSIKVNRHLQTVNN 59
N++ + A + F + ++A ++L+ T++GN LVM++ + L+T NN
Sbjct: 11 NASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNN 70
Query: 60 YFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISF 119
+FL +LA +D ++G F + LY Y + G W G +C LWL +DY++ +S N+++IS+
Sbjct: 71 FFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISY 130
Query: 120 DRYFCVTKPLTYPVKR-TTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYI 178
DR+ VT+ ++Y ++ T+ A + WVL+F+L+ PAIL W+++ G ++ +G CY
Sbjct: 131 DRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYA 190
Query: 179 QFFSNAAVTFGTAIAAFYLPVIIMTV----LYWHISRASKSRIKKDKK------EPVANQ 228
+FF N + F+ P + +T +Y +I R ++ R+ ++ P A
Sbjct: 191 EFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQP 250
Query: 229 DPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESS-NDST 287
P P G K + MP G V E V E E++
Sbjct: 251 SPPPPPGCWGCWQKGHGEAMPLHRYG---------------VGEAAVGAEAGEATLGGGG 295
Query: 288 SVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVV 347
+VAS ++S G S + ++ G+K P + S +
Sbjct: 296 GGGSVAS-------------PTSSSGSSSRGTERPRSLKRGSK-PSASSAS--------- 332
Query: 348 GSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMV 407
K +KM Q ++ SR++KV +++ I+ F + WAPY +++
Sbjct: 333 --------------LEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLM 378
Query: 408 LINTFC-APCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL 455
+I C C+P+ + +WL + NS +NP Y LC+ +F++ F LL
Sbjct: 379 IIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLL 427
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 173 bits (439), Expect = 3e-43
Identities = 130/470 (27%), Positives = 220/470 (46%), Gaps = 72/470 (15%)
Query: 2 NNSTN------SSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQ 55
NN+T+ + N+ ++ +++V+ +L+ G+L ++GN V+ +I + R LQ
Sbjct: 10 NNTTSPPAPFETGGNTTGISDVTVSYQVITSLLL-GTLIFCAVLGNACVVAAIALERSLQ 68
Query: 56 TVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLL 115
V NY + SLA DL++ V + + LY V+ W LG V CDL++ALD + +S+++L
Sbjct: 69 NVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLC 128
Query: 116 IISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVED-- 173
I+ DRY+ +T P+ Y KRT + A +I+ W++ F++ P +L W RT ED
Sbjct: 129 AIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGW------RTPEDRS 182
Query: 174 --GECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV 231
C I + T + AFY+P+++M VLY I RA++ RI+K K
Sbjct: 183 DPDACTIS--KDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVK--------- 231
Query: 232 SPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSA 291
++ K + + + K NG++ + N G E ++ + A
Sbjct: 232 -------KVEKTGADTRHGASPAPQPKKSVNGESG----SRNWRLGVESKAGGALCANGA 280
Query: 292 VASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSG 351
V DD + V +G+SK+ P PT +S
Sbjct: 281 VRQG--DDGAALEVIEVH-RVGNSKEH------------LPLPSEAGPT----PCAPASF 321
Query: 352 QNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINT 411
+ +E+ AK+K +RE+K +T+ I+ FI+ W P+ ++ L+
Sbjct: 322 ERKNER------------NAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLP 369
Query: 412 FC-APC-IPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHY 459
FC + C +P + I WL Y NS +NP YA N F+ FK ++ C +
Sbjct: 370 FCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKF 419
>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
Length = 414
Score = 150 bits (378), Expect = 3e-36
Identities = 112/444 (25%), Positives = 186/444 (41%), Gaps = 67/444 (15%)
Query: 18 YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77
Y + + +L+A V + GN+LV +++ + LQT NY + SLA ADL++ M
Sbjct: 34 YNYYATLLTLLIA-----VIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVM 88
Query: 78 NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137
V+G W + CD+++ LD ++ AS++NL IS DRY V P+ Y + ++
Sbjct: 89 PWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSS 148
Query: 138 K-MAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFY 196
K +MI+ WVLSF + P + G+ + EC I +N A ++I +FY
Sbjct: 149 KRRVTVMISIVWVLSFTISCP------LLFGLNNADQNECII---ANPAFVVYSSIVSFY 199
Query: 197 LPVIIMTVLY---WHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253
+P I+ ++Y + + R + R+ + +P R + M SS
Sbjct: 200 VPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKEAARRAQELEMEMLSSTS 259
Query: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313
E + +P P + ST D ++N G
Sbjct: 260 PPERTRY----SPIPPSHHQLTLPDPSHHGLHSTP---------DSPAKPEKN------G 300
Query: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373
H+KD I T NG + ++ K +
Sbjct: 301 HAKDHPKIAKIFEIQTM---------------------PNGKTRTSL---------KTMS 330
Query: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINS 433
++K +EKK T+ + +L FII W P+ + ++N C IP +++ WL Y+NS
Sbjct: 331 RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS 390
Query: 434 TINPACYALCNATFKKTFKHLLMC 457
+NP Y N F+K F +L C
Sbjct: 391 AVNPIIYTTFNIEFRKAFLKILHC 414
>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
Length = 443
Score = 149 bits (376), Expect = 5e-36
Identities = 113/452 (25%), Positives = 193/452 (42%), Gaps = 54/452 (11%)
Query: 18 YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77
Y + + +L+A V + GN+LV +++ + LQT NY + SLA ADL++ M
Sbjct: 34 YNYYATLLTLLIA-----VIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVM 88
Query: 78 NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137
V+G W + CD+++ LD ++ AS++NL IS DRY V P+ Y + ++
Sbjct: 89 PWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSS 148
Query: 138 K-MAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFY 196
K +MI+ WVLSF + P + G+ + EC I +N A ++I +FY
Sbjct: 149 KRRVTVMISIVWVLSFTISCP------LLFGLNNADQNECII---ANPAFVVYSSIVSFY 199
Query: 197 LPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLE 256
+P I+ ++Y I + R K+ + S + + P N +D
Sbjct: 200 VPFIVTLLVYIKIYIVLRRRRKRVNTKR-------SSRAFRAHLRAPLKGNCTHPEDMKL 252
Query: 257 HNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSK 316
I PV V+ + + +S+ + E T + + S
Sbjct: 253 CTVIMKSNG-SFPVNRRRVEAARRAQELEMEMLSST---------SPPERTRYSPIPPSH 302
Query: 317 DENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQP---- 372
+ T S ++T + +NG K + KI ++ P
Sbjct: 303 HQ-----------LTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKT 351
Query: 373 -------AKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIG 425
+++K +EKK T+ + +L FII W P+ + ++N C IP +++
Sbjct: 352 RTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAF 411
Query: 426 YWLCYINSTINPACYALCNATFKKTFKHLLMC 457
WL Y+NS +NP Y N F+K F +L C
Sbjct: 412 TWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 443
>gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens]
Length = 465
Score = 149 bits (375), Expect = 7e-36
Identities = 105/445 (23%), Positives = 199/445 (44%), Gaps = 28/445 (6%)
Query: 13 ALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLII 72
A +PY + +V +AG L L+T+ GN+LV++++ +R L+ N FL SLA AD+++
Sbjct: 38 ARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILV 97
Query: 73 GVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYP 132
+ V+GYW G C+++LALD + +S+++L IS DRY+ +T+ + Y
Sbjct: 98 ATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYN 157
Query: 133 VKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAI 192
+KRT + +I WV+S ++ P ++ + G + E + + I
Sbjct: 158 LKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCI 217
Query: 193 AAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSD 252
+F+ P +IM ++Y I + +K R + P + + P + + G + N P
Sbjct: 218 GSFFAPCLIMILVYVRIYQIAKRRTRV----PPSRRGPDAVAAPPGGTERRPNGLGPERS 273
Query: 253 DGLEHNKIQNGKAPRDPVTE--NCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVST 310
G G A +P+ N GE + T + + D +
Sbjct: 274 AG-------PGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRP 326
Query: 311 SLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTK 370
G ++ + ++ G P+ P T + + G ++ + A K
Sbjct: 327 ERGPRGKGKARASQVKPGDSLPRRG---PGATGIGTPAA----GPGEERVGAAKA----- 374
Query: 371 QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCY 430
++ + +REK+ T + ++ F++ W P+ + T +P T++ +W Y
Sbjct: 375 --SRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTL-TAVGCSVPRTLFKFFFWFGY 431
Query: 431 INSTINPACYALCNATFKKTFKHLL 455
NS++NP Y + N F++ FK +L
Sbjct: 432 CNSSLNPVIYTIFNHDFRRAFKKIL 456
>gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]
Length = 462
Score = 137 bits (345), Expect = 2e-32
Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)
Query: 18 YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77
Y V + V G L + T++GN+LV++++ +R L+ N FL SLA AD+++ M
Sbjct: 46 YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
Query: 78 NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137
++ YW G V C ++LALD + +S+++L IS DRY+ VT+ + Y +KRT
Sbjct: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
Query: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195
+ I A W++S ++ P +V + DG Y Q N + + I +F
Sbjct: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
Query: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253
+ P +IM ++Y I R +K R + +K+ PV D SP+ G
Sbjct: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
Query: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313
G +NG P V+ +E ++ + A E + G
Sbjct: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
Query: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373
+ ++ +++P ++ V + + ++ RK+ + A
Sbjct: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
Query: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431
++K + T + ++ F++ W P+ + C A +P ++ +W+ Y
Sbjct: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
Query: 432 NSTINPACYALCNATFKKTFKHLL 455
NS++NP Y + N F+++FKH+L
Sbjct: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
Length = 450
Score = 136 bits (342), Expect = 5e-32
Identities = 103/454 (22%), Positives = 201/454 (44%), Gaps = 33/454 (7%)
Query: 17 PYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFS 76
PY I L L TI GN LV++++ +R L+ N FL SLA AD+++
Sbjct: 6 PYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLI 65
Query: 77 MNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRT 136
+ ++GYW C+++LALD + +S+++L IS DRY+ V++ L Y KRT
Sbjct: 66 IPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRT 125
Query: 137 TKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFY 196
+ +I W+++ ++ P +++ + G + +C + A ++I +F+
Sbjct: 126 PRRIKCIILTVWLIAAVISLPPLIY-KGDQGPQPRGRPQCKLN--QEAWYILASSIGSFF 182
Query: 197 LPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGR---------IVKPNNNN 247
P +IM ++Y I +K + +++ P A P Q R P +
Sbjct: 183 APCLIMILVYLRIYLIAK---RSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALAS 239
Query: 248 MPSSDDGLEHNKI----QNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQ 303
+ S+ + H+K + G+ P D T ++ V +DE +
Sbjct: 240 VASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEE 299
Query: 304 DENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVAR 363
+E ++E ++ C + +C+P + GS Q ++ R
Sbjct: 300 EE----------EEEEEEEECEPQAVPVSPASACSP--PLQQPQGSRVLATLRGQVLLGR 347
Query: 364 KIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAP-C-IPNTV 421
+ + Q +++ +REK+ T + ++ F++ W P+ + C C +P+ +
Sbjct: 348 GVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGL 407
Query: 422 WTIGYWLCYINSTINPACYALCNATFKKTFKHLL 455
+ +W+ Y NS++NP Y + N F++ F+ +L
Sbjct: 408 FQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL 441
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 133 bits (335), Expect = 3e-31
Identities = 70/230 (30%), Positives = 121/230 (52%), Gaps = 12/230 (5%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
++ + + S+N +P + + + ++ G L L ++GNILV++S+ +RHL +V +Y
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
++ +LA ADL++ + ++ V+GYW G V C++W A+D + AS+M L IIS D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RY V+ PL YP T + M + W LS ++ + W+ + + E Q
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWR-----QPAPEDETICQI 178
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHI-------SRASKSRIKKDKKE 223
+A+ +FYLP+ I+ V+Y + SR KS +K DK +
Sbjct: 179 NEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSD 228
Score = 62.8 bits (151), Expect = 7e-10
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 325 IRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKK 384
++ G KT KSDS T +G +G V++ K SREKK
Sbjct: 218 LKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF--------SREKK 269
Query: 385 VTRTILAILLAFIITWAPYNVMVLINTFCAPCIPN-TVWTIGYWLCYINSTINPACYALC 443
+T+ ++ F++ W P+ +++ I +F P+ TV+ I +WL Y+NS INP Y
Sbjct: 270 AAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCS 329
Query: 444 NATFKKTFKHLL 455
+ FKK F+++L
Sbjct: 330 SQEFKKAFQNVL 341
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 133 bits (335), Expect = 3e-31
Identities = 70/230 (30%), Positives = 121/230 (52%), Gaps = 12/230 (5%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
++ + + S+N +P + + + ++ G L L ++GNILV++S+ +RHL +V +Y
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
++ +LA ADL++ + ++ V+GYW G V C++W A+D + AS+M L IIS D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RY V+ PL YP T + M + W LS ++ + W+ + + E Q
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWR-----QPAPEDETICQI 178
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHI-------SRASKSRIKKDKKE 223
+A+ +FYLP+ I+ V+Y + SR KS +K DK +
Sbjct: 179 NEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSD 228
Score = 62.8 bits (151), Expect = 7e-10
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 325 IRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKK 384
++ G KT KSDS T +G +G V++ K SREKK
Sbjct: 218 LKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF--------SREKK 269
Query: 385 VTRTILAILLAFIITWAPYNVMVLINTFCAPCIPN-TVWTIGYWLCYINSTINPACYALC 443
+T+ ++ F++ W P+ +++ I +F P+ TV+ I +WL Y+NS INP Y
Sbjct: 270 AAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCS 329
Query: 444 NATFKKTFKHLL 455
+ FKK F+++L
Sbjct: 330 SQEFKKAFQNVL 341
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 133 bits (335), Expect = 3e-31
Identities = 70/230 (30%), Positives = 121/230 (52%), Gaps = 12/230 (5%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
++ + + S+N +P + + + ++ G L L ++GNILV++S+ +RHL +V +Y
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
++ +LA ADL++ + ++ V+GYW G V C++W A+D + AS+M L IIS D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RY V+ PL YP T + M + W LS ++ + W+ + + E Q
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWR-----QPAPEDETICQI 178
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHI-------SRASKSRIKKDKKE 223
+A+ +FYLP+ I+ V+Y + SR KS +K DK +
Sbjct: 179 NEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSD 228
Score = 62.8 bits (151), Expect = 7e-10
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 325 IRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKK 384
++ G KT KSDS T +G +G V++ K SREKK
Sbjct: 218 LKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF--------SREKK 269
Query: 385 VTRTILAILLAFIITWAPYNVMVLINTFCAPCIPN-TVWTIGYWLCYINSTINPACYALC 443
+T+ ++ F++ W P+ +++ I +F P+ TV+ I +WL Y+NS INP Y
Sbjct: 270 AAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCS 329
Query: 444 NATFKKTFKHLL 455
+ FKK F+++L
Sbjct: 330 SQEFKKAFQNVL 341
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 133 bits (335), Expect = 3e-31
Identities = 70/230 (30%), Positives = 121/230 (52%), Gaps = 12/230 (5%)
Query: 1 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY 60
++ + + S+N +P + + + ++ G L L ++GNILV++S+ +RHL +V +Y
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 61 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD 120
++ +LA ADL++ + ++ V+GYW G V C++W A+D + AS+M L IIS D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 121 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF 180
RY V+ PL YP T + M + W LS ++ + W+ + + E Q
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWR-----QPAPEDETICQI 178
Query: 181 FSNAAVTFGTAIAAFYLPVIIMTVLYWHI-------SRASKSRIKKDKKE 223
+A+ +FYLP+ I+ V+Y + SR KS +K DK +
Sbjct: 179 NEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSD 228
Score = 62.8 bits (151), Expect = 7e-10
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 325 IRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKK 384
++ G KT KSDS T +G +G V++ K SREKK
Sbjct: 218 LKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF--------SREKK 269
Query: 385 VTRTILAILLAFIITWAPYNVMVLINTFCAPCIPN-TVWTIGYWLCYINSTINPACYALC 443
+T+ ++ F++ W P+ +++ I +F P+ TV+ I +WL Y+NS INP Y
Sbjct: 270 AAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCS 329
Query: 444 NATFKKTFKHLL 455
+ FKK F+++L
Sbjct: 330 SQEFKKAFQNVL 341
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 131 bits (330), Expect = 1e-30
Identities = 72/207 (34%), Positives = 112/207 (54%), Gaps = 8/207 (3%)
Query: 13 ALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLII 72
+++ P+K V +V++ ++L T + N V+ ++ R L T NY + SLA DL++
Sbjct: 43 SISLPWK----VLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLV 98
Query: 73 GVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYP 132
+ M + T+YTV G W LG VVCD WL+ D AS+++L +I+ DRY+ +T + Y
Sbjct: 99 SILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYS 158
Query: 133 VKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAI 192
KRT K A +MIA WV S + P FW+ V EC + + T + +
Sbjct: 159 AKRTPKRAAVMIALVWVFSISISLPP-FFWRQAKAEEEV--SECVVN-TDHILYTVYSTV 214
Query: 193 AAFYLPVIIMTVLYWHISRASKSRIKK 219
AFY P +++ LY I ++SRI K
Sbjct: 215 GAFYFPTLLLIALYGRIYVEARSRILK 241
Score = 60.8 bits (146), Expect = 2e-09
Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Query: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431
KKK +RE+K T+T+ IL AFI+ W P+ ++ L+ C A ++ WL Y+
Sbjct: 301 KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL 360
Query: 432 NSTINPACYALCNATFKKTFKHLL 455
NS INP Y + N FK+ F L+
Sbjct: 361 NSLINPIIYTMSNEDFKQAFHKLI 384
>gi|32483397 dopamine receptor D4 [Homo sapiens]
Length = 419
Score = 127 bits (319), Expect = 2e-29
Identities = 110/431 (25%), Positives = 182/431 (42%), Gaps = 56/431 (12%)
Query: 28 LVAGSLSLVTII-GNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVI 86
LV G L + ++ GN LV VS+ R LQT N F+ SLA ADL++ + + L+ V
Sbjct: 38 LVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQ 97
Query: 87 G-YWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIA 145
G W L P +CD +A+D ++ AS+ NL IS DR+ V PL Y + ++ ++I
Sbjct: 98 GGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIG 157
Query: 146 AAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVL 205
A W+LS + AP + G+ V + + + +++ +F+LP +M +L
Sbjct: 158 ATWLLSAAVAAPV------LCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLL 211
Query: 206 YWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKA 265
YW R + R + ++ + + P PS P +P G + G
Sbjct: 212 YWATFRGLQ-RWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPG-L 269
Query: 266 PRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCI 325
PR P +C + A ++ D D + L
Sbjct: 270 PRGPCGPDC---------------APAAPSLPQDPCGPDCAPPAPGL------------- 301
Query: 326 RIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKV 385
P +C P + V Q + + R+ K+T RE+K
Sbjct: 302 ---PPDPCGSNCAPPD-AVRAAALPPQTPPQTRR---RRRAKIT----------GRERKA 344
Query: 386 TRTILAILLAFIITWAPYNVMVLINTFCAPC-IPNTVWTIGYWLCYINSTINPACYALCN 444
R + ++ AF++ W P+ V+ + C C +P + + WL Y+NS +NP Y + N
Sbjct: 345 MRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFN 404
Query: 445 ATFKKTFKHLL 455
A F+ F+ L
Sbjct: 405 AEFRNVFRKAL 415
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 125 bits (315), Expect = 6e-29
Identities = 68/216 (31%), Positives = 113/216 (52%), Gaps = 4/216 (1%)
Query: 2 NNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYF 61
N S N++ S A + + +V ++L T++ N V+ +I + R L T NY
Sbjct: 17 NRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYL 76
Query: 62 LFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDR 121
+ SLA DL++ + M + YT+ W G ++CD+WL+ D AS+++L +I+ DR
Sbjct: 77 IGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDR 136
Query: 122 YFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFF 181
Y+ +T L Y +RT A MIA W +S + P LFW+ + D C +
Sbjct: 137 YWAITDALEYSKRRTAGHAATMIAIVWAISICISIPP-LFWRQAKAQEEMSD--CLVN-T 192
Query: 182 SNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRI 217
S + T + AFY+P +++ +LY I RA+++RI
Sbjct: 193 SQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRI 228
Score = 55.1 bits (131), Expect = 1e-07
Identities = 29/84 (34%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Query: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPC--IPNTVWTIGYWLCYI 431
+K+ +RE+K T+ + IL AFII W P+ V+ L+ C I ++ WL Y+
Sbjct: 288 RKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYL 347
Query: 432 NSTINPACYALCNATFKKTFKHLL 455
NS INP Y + N F++ F+ ++
Sbjct: 348 NSLINPIIYTVFNEEFRQAFQKIV 371
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,714,878
Number of Sequences: 37866
Number of extensions: 714480
Number of successful extensions: 4585
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 566
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 2891
Number of HSP's gapped (non-prelim): 1277
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.