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Search of human proteins with 54607033
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
(1752 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 3607 0.0
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 3582 0.0
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 3489 0.0
gi|47078292 integrin beta chain, beta 3 precursor [Homo sapiens] 450 e-126
gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens] 447 e-125
gi|19743815 integrin beta 1 isoform 1B precursor [Homo sapiens] 447 e-125
gi|19743813 integrin beta 1 isoform 1A precursor [Homo sapiens] 447 e-125
gi|19743823 integrin beta 1 isoform 1A precursor [Homo sapiens] 447 e-125
gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens] 447 e-125
gi|19743819 integrin beta 1 isoform 1D precursor [Homo sapiens] 447 e-125
gi|20127446 integrin, beta 5 [Homo sapiens] 436 e-121
gi|9625002 integrin, beta 6 [Homo sapiens] 433 e-121
gi|188595677 integrin, beta 2 precursor [Homo sapiens] 394 e-109
gi|89191865 integrin, beta 2 precursor [Homo sapiens] 394 e-109
gi|4504777 integrin, beta 7 [Homo sapiens] 387 e-107
gi|4504779 integrin, beta 8 precursor [Homo sapiens] 323 1e-87
gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 140 1e-32
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 101 7e-21
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 100 1e-20
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 100 1e-20
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 98 6e-20
gi|119220552 sidekick 1 [Homo sapiens] 97 1e-19
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 97 1e-19
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 97 2e-19
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 97 2e-19
gi|222537743 protein tyrosine phosphatase, receptor type, Q [Hom... 95 7e-19
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 93 3e-18
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 91 8e-18
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 91 8e-18
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 91 8e-18
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 3607 bits (9353), Expect = 0.0
Identities = 1752/1752 (100%), Positives = 1752/1752 (100%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
Query: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY
Sbjct: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
Query: 1441 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1500
STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG
Sbjct: 1441 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1500
Query: 1501 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1560
ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP
Sbjct: 1501 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1560
Query: 1561 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF 1620
LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF
Sbjct: 1561 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF 1620
Query: 1621 RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAG 1680
RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAG
Sbjct: 1621 RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAG 1680
Query: 1681 LFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGT 1740
LFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGT
Sbjct: 1681 LFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGT 1740
Query: 1741 LSTHMDQQFFQT 1752
LSTHMDQQFFQT
Sbjct: 1741 LSTHMDQQFFQT 1752
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 3582 bits (9289), Expect = 0.0
Identities = 1752/1805 (97%), Positives = 1752/1805 (97%), Gaps = 53/1805 (2%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
Query: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY
Sbjct: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
Query: 1441 STLTSVSSH--------------------------------------------------- 1449
STLTSVSSH
Sbjct: 1441 STLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPSW 1500
Query: 1450 --DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI 1507
DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI
Sbjct: 1501 GPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI 1560
Query: 1508 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT 1567
PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT
Sbjct: 1561 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT 1620
Query: 1568 LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1627
LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP
Sbjct: 1621 LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1680
Query: 1628 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1687
ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ
Sbjct: 1681 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1740
Query: 1688 SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ 1747
SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ
Sbjct: 1741 SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ 1800
Query: 1748 QFFQT 1752
QFFQT
Sbjct: 1801 QFFQT 1805
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 3489 bits (9048), Expect = 0.0
Identities = 1723/1824 (94%), Positives = 1728/1824 (94%), Gaps = 74/1824 (4%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT----------- 1369
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG 1380
Query: 1370 EHLVNGRMDFAFP------------------------------GSTNSLHRMTTTSAAAY 1399
E L R+ + P G SL R T
Sbjct: 1381 EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPP-- 1438
Query: 1400 GTHL-----------SPHVPHRVLSTS--------------------STLTRDYNSLTRS 1428
G HL S + HR+ +TS STLTRDYNSLTRS
Sbjct: 1439 GEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRS 1498
Query: 1429 EHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQ 1488
EHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQ
Sbjct: 1499 EHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQ 1558
Query: 1489 GYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI 1548
GYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI
Sbjct: 1559 GYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI 1618
Query: 1549 ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTC 1608
ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTC
Sbjct: 1619 ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTC 1678
Query: 1609 EMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD 1668
EMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD
Sbjct: 1679 EMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD 1738
Query: 1669 GGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQ 1728
GGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQ
Sbjct: 1739 GGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQ 1798
Query: 1729 EFVSRTLTTSGTLSTHMDQQFFQT 1752
EFVSRTLTTSGTLSTHMDQQFFQT
Sbjct: 1799 EFVSRTLTTSGTLSTHMDQQFFQT 1822
>gi|47078292 integrin beta chain, beta 3 precursor [Homo sapiens]
Length = 788
Score = 450 bits (1158), Expect = e-126
Identities = 272/761 (35%), Positives = 404/761 (53%), Gaps = 49/761 (6%)
Query: 2 AGPRPSP-WARLL-LAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFR-- 57
A PRP P WA +L L AL V + G N C V SC +C+ V CA+C+DE
Sbjct: 3 ARPRPRPLWATVLALGALAGVGVGGP--NICTTRGVSSCQQCLAVSPMCAWCSDEALPLG 60
Query: 58 DRRCNTQAELLAAGCQRESIVVMESSFQITEETQIDT-----TLRRSQMSPQGLRVRLRP 112
RC+ + LL C ESI S ++ E+ + + + +Q+SPQ + +RLRP
Sbjct: 61 SPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRP 120
Query: 113 GEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFG 172
+ ++F ++V + + PVD+Y LMD S SM DDL +++ +G LA + +LTS+ IGFG
Sbjct: 121 DDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFG 180
Query: 173 KFVDKVSVPQTDMRP-EKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISG 227
FVDK P + P E L+ P + P F +K+V++LT+ V F +++ + +S
Sbjct: 181 AFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSR 240
Query: 228 NLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDER 287
N DAPEGGFDAI+Q VC IGWR D++HLLVF+T++ H DG LAGI+ ND +
Sbjct: 241 NRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGR--LAGIVQPNDGQ 298
Query: 288 CHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGV 347
CH+ + Y+ T DYPS+ + L++ NI IFAVT + Y+ P +++GV
Sbjct: 299 CHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGV 358
Query: 348 LQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKT----RTGSFHIRRG 403
L DSSN+++L+ +A+ +IRS +++ D P L + ++ G
Sbjct: 359 LSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIG 418
Query: 404 EVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKE 462
+ + ++ + V P++++ + +KP F D L + CD C C+ Q E
Sbjct: 419 DTVSFSIEAK---------VRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCD-CACQAQAE 468
Query: 463 VRSARCSF-NGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGEC 518
S RC+ NG F CG C C GW G C CS Q REG+ CS RGEC
Sbjct: 469 PNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPV-CSQRGEC 527
Query: 519 QCGHCVCYGE--GRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCP 576
CG CVC+ G+ G++CE D+F C R G +C+ G+CS G C+C+ WTG C+C
Sbjct: 528 LCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCT 587
Query: 577 LSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQ 636
TC+ SNG +C+GRG CECG C C Q Y DT CE P C + CV+C+
Sbjct: 588 TRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDT-CE--KCPTCPDACTFKKECVECK 644
Query: 637 AWGTGE-KKGRTCEE-CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGP 694
+ G TC C +++ V ELK + V C++++E DDC + D +
Sbjct: 645 KFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNE-DDCVVRFQYYEDSS--G 701
Query: 695 NSTVLVHKKKDCPPGSFWWLIPLLLL-LLPLLALLLLLCWK 734
S + V ++ +CP G ++ L ++ + L+ L LL WK
Sbjct: 702 KSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWK 742
>gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens]
Length = 825
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743815 integrin beta 1 isoform 1B precursor [Homo sapiens]
Length = 789
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743813 integrin beta 1 isoform 1A precursor [Homo sapiens]
Length = 798
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743823 integrin beta 1 isoform 1A precursor [Homo sapiens]
Length = 798
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens]
Length = 819
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743819 integrin beta 1 isoform 1D precursor [Homo sapiens]
Length = 801
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|20127446 integrin, beta 5 [Homo sapiens]
Length = 799
Score = 436 bits (1120), Expect = e-121
Identities = 273/768 (35%), Positives = 390/768 (50%), Gaps = 68/768 (8%)
Query: 6 PSP-WARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRD-----R 59
P+P +A LL + L+G N C SC EC+ + CA+C+ E F
Sbjct: 5 PAPLYACLLGLCALLPRLAGL--NICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITS 62
Query: 60 RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRS------QMSPQGLRVRLRPG 113
RC+ +A L+ GC E I SSF + + + S QM+PQ + V LRPG
Sbjct: 63 RCDLRANLVKNGCGGE-IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPG 121
Query: 114 EERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGK 173
++ F+L+V + + PVDLY LMD S SM DDLDN++ +G LA + +LTS++ +GFG
Sbjct: 122 DKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGS 181
Query: 174 FVDKVSVPQTDMRPEKLKEP------WPNSDPPFSFKNVISLTEDVDEFRNKLQGERISG 227
FVDK P + P P +PN P F F++++ LT+ VD F +++ +R+S
Sbjct: 182 FVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSR 241
Query: 228 NLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDER 287
N DAPEGGFDA+LQ AVC IGWR D+ HLLVF+T+ H DG L G++ +D +
Sbjct: 242 NRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGK--LGGLVQPHDGQ 299
Query: 288 CHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGV 347
CHL+ YT DYPS+ L LA++NI IFAVT Y Y+ P +++ +
Sbjct: 300 CHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEI 359
Query: 348 LQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVT-------SKMFQKTRTGSFHI 400
L DS NI++L+ A+N IRS +++ D P L T S Q+ G +
Sbjct: 360 LDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEG---L 416
Query: 401 RRGEVGIYQVQLRA-------LEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIIC 452
+ G+ ++V L A EHV L+P F D L++ C
Sbjct: 417 KIGDTASFEVSLEARSCPSRHTEHV---------------FALRPVGFRDSLEVGVTYNC 461
Query: 453 DVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDI-QPCLREGEDKP 511
C C + E SARC+ +G +VCG C CS G+ G C C G + Q RE E KP
Sbjct: 462 -TCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKP 520
Query: 512 -CSGRGECQCGHCVCYGE--GRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGW 568
CSGRG+C C C C+ G+ G FCE DNF C R G LC+ G C G+C C G+
Sbjct: 521 LCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGY 580
Query: 569 TGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCED 628
G +C+C +TC +G IC+ RGHC CG+C C + + + +CE P C
Sbjct: 581 IGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEPGAFGE-MCE--KCPTCPDACST 637
Query: 629 LRSCVQCQAWGTGEKKGRTCEE-CNFKV-KMVDELKRAEEVVVRCSFRDEDDDCTYSYTM 686
R CV+C +G+ +TC C +V VD + + ++ V C ++ DC +T
Sbjct: 638 KRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTA-KDCVMMFTY 696
Query: 687 EGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLLLLPLLALLLLLCWK 734
+ N TVL + P + L+ ++ +L L+ L LL WK
Sbjct: 697 VELPSGKSNLTVLREPECGNTPNAMTILLAVVGSIL-LVGLALLAIWK 743
>gi|9625002 integrin, beta 6 [Homo sapiens]
Length = 788
Score = 433 bits (1113), Expect = e-121
Identities = 248/733 (33%), Positives = 385/733 (52%), Gaps = 52/733 (7%)
Query: 30 CKKAPVKSCTECVRVDKDCAYCTDEMFRD-----RRCNTQAELLAAGCQRESIVVMESSF 84
C ++C +C+ + CA+C E F RC+T A LLA GCQ I S
Sbjct: 23 CALGGAETCEDCLLIGPQCAWCAQENFTHPSGVGERCDTPANLLAKGCQLNFIENPVSQV 82
Query: 85 QITEETQIDTTLRRS-----QMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFS 139
+I + + +++ Q++PQ L ++LRPG + ++ V + + PVDLY LMD S
Sbjct: 83 EILKNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLYYLMDLS 142
Query: 140 NSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWPNSD- 198
SM DDL+ +K++G L++ +S+LTS++ +GFG FV+K P PE++ P +
Sbjct: 143 ASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPY 202
Query: 199 ---PPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDS 255
P F FK+++ LT D + F ++ ++IS N+D PEGGFDAI+Q AVC IGWR DS
Sbjct: 203 FCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDS 262
Query: 256 THLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLA 315
HLLVF +++ H+ D LAGI+ ND CHLD+ Y+ +YP++ L+ L
Sbjct: 263 LHLLVFVSDADSHFGMDSK--LAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLV 320
Query: 316 KHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLDIRAL 375
++N++ IFAVT YE P +++G+LQ+DS NI++L+ A+ +RS +++ L
Sbjct: 321 QNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVL 380
Query: 376 DSPRGLRTEVTS-----KMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQ 430
GL T+ +FQ + S H++ G+ + V + + H E +
Sbjct: 381 GDTEGLNLSFTAICNNGTLFQHQKKCS-HMKVGDTASFSVTVN-IPHC---------ERR 429
Query: 431 KGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARCSF-NGDFVCGQCVCSEGWSGQ 488
+I +KP D L++ C+ C C+ + EV S++C NG F CG C C G G
Sbjct: 430 SRHIIIKPVGLGDALELLVSPECN-CDCQKEVEVNSSKCHHGNGSFQCGVCACHPGHMGP 488
Query: 489 TCNCSTGSLSDIQPCLREGEDKP-CSGRGECQCGHCVCYGE--GRYEGQFCEYDNFQCPR 545
C C LS +E D P CSGRG+C CG C+C+ G G +C+ DNF C R
Sbjct: 489 RCECGEDMLST--DSCKEAPDHPSCSGRGDCYCGQCICHLSPYGNIYGPYCQCDNFSCVR 546
Query: 546 TSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQ 605
G LC G C G+CVC GWTG C+C S +C+ +G +C+GRG C CG+C C
Sbjct: 547 HKGLLCGGNGDCDCGECVCRSGWTGEYCNCTTSTDSCVSEDGVLCSGRGDCVCGKCVCTN 606
Query: 606 QSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKR-A 664
T CE + P C RSC++C G+ + ++C + E + +
Sbjct: 607 PGASGPT-CERCPTCGDP--CNSKRSCIECHLSAAGQAREECVDKCKLAGATISEEEDFS 663
Query: 665 EEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCP-PGSFWWLIPLLLLL 721
++ V CS + E ++C ++ + D ++H +KDCP P + ++ + L
Sbjct: 664 KDGSVSCSLQGE-NECLITFLITTDN----EGKTIIHSINEKDCPKPPNIPMIMLGVSLA 718
Query: 722 LPLLALLLLLCWK 734
+ L+ ++LL WK
Sbjct: 719 ILLIGVVLLCIWK 731
>gi|188595677 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 394 bits (1012), Expect = e-109
Identities = 273/805 (33%), Positives = 399/805 (49%), Gaps = 73/805 (9%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR- 59
M G RP LLA + +SL L+ C K V SC EC+ C +C F
Sbjct: 1 MLGLRPP-----LLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPG 55
Query: 60 -----RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGE 114
RC+T+ +LL GC + I+ S ETQ D + Q+SPQ + + LRPG+
Sbjct: 56 DPDSIRCDTRPQLLMRGCAADDIMDPTS----LAETQEDHNGGQKQLSPQKVTLYLRPGQ 111
Query: 115 ERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKF 174
F + P+DLY LMD S SM DDL N+KK+G +L R L+++T IGFG F
Sbjct: 112 AAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSF 171
Query: 175 VDKVSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLD 230
VDK +P + P+KL+ P PN + PPF+F++V+ LT + ++F+ ++ + ISGNLD
Sbjct: 172 VDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLD 231
Query: 231 APEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHL 290
APEGG DA++Q A C +IGWR + T LLVF+T+ FH+ DG L I++ ND RCHL
Sbjct: 232 APEGGLDAMMQVAACPEEIGWR-NVTRLLVFATDDGFHFAGDGK--LGAILTPNDGRCHL 288
Query: 291 DTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQE 350
+ Y + DYPSV L LA++NI PIFAVT+ YEKL P S++G L E
Sbjct: 289 E-DNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSE 347
Query: 351 DSSNIVELLEEAFNRIRSN--LDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIY 408
DSSN+V+L++ A+N++ S LD AL +VT F + RG+
Sbjct: 348 DSSNVVQLIKNAYNKLSSRVFLDHNALPD----TLKVTYDSFCSNGVTHRNQPRGDCDGV 403
Query: 409 QVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARC 468
Q+ + V T + ++Q I F+D + + C+ C C Q RS C
Sbjct: 404 QINVPITFQVKVT-ATECIQEQSFVIRAL-GFTDIVTVQVLPQCE-CRCRDQSRDRSL-C 459
Query: 469 SFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQ---PCLREGEDKPCSGRGECQCGHCVC 525
G CG C C G+ G+ C C T S + C ++ CSG G+C CG C+C
Sbjct: 460 HGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLC 519
Query: 526 Y-----GEGRYEGQFCEYDNFQCPRTSGFLCN--DRGRCSMGQCVCEPGWTGPSCDCPLS 578
+ G+ Y GQ+CE D C R +G +C RG C G+C C PG+ G +C C +
Sbjct: 520 HTSDVPGKLIY-GQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERT 578
Query: 579 NATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAW 638
C++ C+GRG C C C CH S Y +C+ P C SC +C +
Sbjct: 579 TEGCLNPRRVECSGRGRCRCNVCECH--SGYQLPLCQECPGC--PSPCGKYISCAECLKF 634
Query: 639 GTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTME-GDGAPGPNST 697
G G+ C +++ + + C RD + C +YT+E DG
Sbjct: 635 EKG-PFGKNCSAACPGLQLSNNPVKGR----TCKERD-SEGCWVAYTLEQQDGM--DRYL 686
Query: 698 VLVHKKKDCPPG-SFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVG 756
+ V + ++C G + ++ + + L+ +LLL+ WK AL+ H+
Sbjct: 687 IYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWK---------ALI------HLSD 731
Query: 757 FKEDHYMLRENLMASDHLDTPMLRS 781
+E +E L + + D P+ +S
Sbjct: 732 LREYRRFEKEKLKSQWNNDNPLFKS 756
>gi|89191865 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 394 bits (1012), Expect = e-109
Identities = 273/805 (33%), Positives = 399/805 (49%), Gaps = 73/805 (9%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR- 59
M G RP LLA + +SL L+ C K V SC EC+ C +C F
Sbjct: 1 MLGLRPP-----LLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPG 55
Query: 60 -----RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGE 114
RC+T+ +LL GC + I+ S ETQ D + Q+SPQ + + LRPG+
Sbjct: 56 DPDSIRCDTRPQLLMRGCAADDIMDPTS----LAETQEDHNGGQKQLSPQKVTLYLRPGQ 111
Query: 115 ERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKF 174
F + P+DLY LMD S SM DDL N+KK+G +L R L+++T IGFG F
Sbjct: 112 AAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSF 171
Query: 175 VDKVSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLD 230
VDK +P + P+KL+ P PN + PPF+F++V+ LT + ++F+ ++ + ISGNLD
Sbjct: 172 VDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLD 231
Query: 231 APEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHL 290
APEGG DA++Q A C +IGWR + T LLVF+T+ FH+ DG L I++ ND RCHL
Sbjct: 232 APEGGLDAMMQVAACPEEIGWR-NVTRLLVFATDDGFHFAGDGK--LGAILTPNDGRCHL 288
Query: 291 DTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQE 350
+ Y + DYPSV L LA++NI PIFAVT+ YEKL P S++G L E
Sbjct: 289 E-DNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSE 347
Query: 351 DSSNIVELLEEAFNRIRSN--LDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIY 408
DSSN+V+L++ A+N++ S LD AL +VT F + RG+
Sbjct: 348 DSSNVVQLIKNAYNKLSSRVFLDHNALPD----TLKVTYDSFCSNGVTHRNQPRGDCDGV 403
Query: 409 QVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARC 468
Q+ + V T + ++Q I F+D + + C+ C C Q RS C
Sbjct: 404 QINVPITFQVKVT-ATECIQEQSFVIRAL-GFTDIVTVQVLPQCE-CRCRDQSRDRSL-C 459
Query: 469 SFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQ---PCLREGEDKPCSGRGECQCGHCVC 525
G CG C C G+ G+ C C T S + C ++ CSG G+C CG C+C
Sbjct: 460 HGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLC 519
Query: 526 Y-----GEGRYEGQFCEYDNFQCPRTSGFLCN--DRGRCSMGQCVCEPGWTGPSCDCPLS 578
+ G+ Y GQ+CE D C R +G +C RG C G+C C PG+ G +C C +
Sbjct: 520 HTSDVPGKLIY-GQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERT 578
Query: 579 NATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAW 638
C++ C+GRG C C C CH S Y +C+ P C SC +C +
Sbjct: 579 TEGCLNPRRVECSGRGRCRCNVCECH--SGYQLPLCQECPGC--PSPCGKYISCAECLKF 634
Query: 639 GTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTME-GDGAPGPNST 697
G G+ C +++ + + C RD + C +YT+E DG
Sbjct: 635 EKG-PFGKNCSAACPGLQLSNNPVKGR----TCKERD-SEGCWVAYTLEQQDGM--DRYL 686
Query: 698 VLVHKKKDCPPG-SFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVG 756
+ V + ++C G + ++ + + L+ +LLL+ WK AL+ H+
Sbjct: 687 IYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWK---------ALI------HLSD 731
Query: 757 FKEDHYMLRENLMASDHLDTPMLRS 781
+E +E L + + D P+ +S
Sbjct: 732 LREYRRFEKEKLKSQWNNDNPLFKS 756
>gi|4504777 integrin, beta 7 [Homo sapiens]
Length = 798
Score = 387 bits (995), Expect = e-107
Identities = 230/643 (35%), Positives = 327/643 (50%), Gaps = 48/643 (7%)
Query: 25 TLANRCKKAPVKSCTECVRVDKDCAYCTDEMF------RDRRCNTQAELLAAGCQRESIV 78
++ C+ AP SC +C+ CA+C F RRC + ELLA GC E +
Sbjct: 40 SMLGSCQPAP--SCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPLEELE 97
Query: 79 VMESSFQITEETQIDTTLR---RSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYIL 135
++ ++ + R +Q++PQ +RV LRPGE + ++ PVDLY L
Sbjct: 98 EPRGQQEVLQDQPLSQGARGEGATQLAPQRVRVTLRPGEPQQLQVRFLRAEGYPVDLYYL 157
Query: 136 MDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWP 195
MD S SM DDL+ ++++G L L ++T IGFG FVDK +P P KL+ P P
Sbjct: 158 MDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLRHPCP 217
Query: 196 NS----DPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGW 251
PFSF +V+SLT D F ++ + +SGNLD+PEGGFDAILQ A+C IGW
Sbjct: 218 TRLERCQSPFSFHHVLSLTGDAQAFEREVGRQSVSGNLDSPEGGFDAILQAALCQEQIGW 277
Query: 252 RPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLV 311
R + + LLVF+++ FH DG L GI +D CHLD+ G Y++ DYPSV +
Sbjct: 278 R-NVSRLLVFTSDDTFHTAGDGK--LGGIFMPSDGHCHLDSNGLYSRSTEFDYPSVGQVA 334
Query: 312 RLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLD 371
+ L+ NI PIFAVT+ + Y++L P S++G L EDSSN+V+L+ +A+N + S +
Sbjct: 335 QALSAANIQPIFAVTSAALPVYQELSKLIPKSAVGELSEDSSNVVQLIMDAYNSLSSTVT 394
Query: 372 IRALDSPRGLRTEVTSKM--------FQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHV 423
+ P G+ S+ + R H+R + + V L+A + H+
Sbjct: 395 LEHSSLPPGVHISYESQCEGPEKREGKAEDRGQCNHVRINQTVTFWVSLQATHCLPEPHL 454
Query: 424 CQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCS-FNGDFVCGQCVCS 482
+L FS+ L ++ +CD C C + ++ CS G CG C C+
Sbjct: 455 LRL---------RALGFSEELIVELHTLCD-CNCS-DTQPQAPHCSDGQGHLQCGVCSCA 503
Query: 483 EGWSGQTCNCSTGSLS--DIQPCLR--EGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEY 538
G G+ C CS LS D++ R G CSG+G CQCG C C G+ G CE
Sbjct: 504 PGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQS--SGHLCEC 561
Query: 539 DNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCEC 598
D+ C R G LC GRC G C C TG +C+C +CI GG+C+G G C+C
Sbjct: 562 DDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKC 621
Query: 599 GRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTG 641
RC C Y +C+ P CE R C +C A+ TG
Sbjct: 622 NRCQCLDG--YYGALCDQCPGCKTP--CERHRDCAECGAFRTG 660
>gi|4504779 integrin, beta 8 precursor [Homo sapiens]
Length = 769
Score = 323 bits (827), Expect = 1e-87
Identities = 207/700 (29%), Positives = 338/700 (48%), Gaps = 67/700 (9%)
Query: 3 GPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMF-----R 57
GP WA + + ++ + NRC + SC C+ + +C +C E F R
Sbjct: 22 GPASFLWAAWVFSLVLGLGQGED--NRCASSNAASCARCLALGPECGWCVQEDFISGGSR 79
Query: 58 DRRCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERH 117
RC+ + L++ GC +SI I E +I+T Q++P + ++LRPG E +
Sbjct: 80 SERCDIVSNLISKGCSVDSIEYPSVHVIIPTENEINT-----QVTPGEVSIQLRPGAEAN 134
Query: 118 FELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDK 177
F L+V + PVDLY L+D S SM ++++ L +G +L+R ++ + D+ +GFG +VDK
Sbjct: 135 FMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDK 194
Query: 178 VSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPE 233
P + PE++ + + PP + +V+SLTE++ EF + ++ISGN+D PE
Sbjct: 195 TVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPE 254
Query: 234 GGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTT 293
GGFDA+LQ AVC IGWR ++ LL+ T+ H D + LAGI+ ND CHL
Sbjct: 255 GGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALD--SKLAGIVVPNDGNCHL-KN 311
Query: 294 GTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSS 353
Y + T ++PS+ L L +NI IFAV + +Y+ L P + G ++ ++
Sbjct: 312 NVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAA 371
Query: 354 NIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTR----TGSFHIRRGEVGIYQ 409
N+ L+ EA+ ++ S + ++ + +G+ +T+ +R G ++ + ++
Sbjct: 372 NLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRKPGMEGCRNVTSNDEVLFN 431
Query: 410 VQLRALEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC 468
V + ++ D T K +KP F++ K+ C C CE + + +C
Sbjct: 432 VTV-TMKKCDVT-------GGKNYAIIKPIGFNETAKIHIHRNCS-CQCEDNRGPK-GKC 481
Query: 469 SFNGDFVCGQCV-CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCY- 526
+ F+ +C C E C+ S + C + CSGRG C CG C C+
Sbjct: 482 -VDETFLDSKCFQCDE----NKCHFDEDQFSS-ESCKSHKDQPVCSGRGVCVCGKCSCHK 535
Query: 527 -GEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNAT-CID 584
G+ G++CE D+F CP G LC G C G+C C GW G C CP + A C++
Sbjct: 536 IKLGKVYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVN 595
Query: 585 SNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKK 644
S G +C+GRG C CGRC C R C C T K+
Sbjct: 596 SKGQVCSGRGTCVCGRCECTDPRSIG-------------------RFCEHCPTCYTACKE 636
Query: 645 GRTCEEC----NFKVKMVDELKRAEEVVVRCSFRDEDDDC 680
C +C N ++D+ K + ++ + + D+ +C
Sbjct: 637 NWNCMQCLHPHNLSQAILDQCKTSCALMEQQHYVDQTSEC 676
>gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains)
[Homo sapiens]
Length = 494
Score = 140 bits (352), Expect = 1e-32
Identities = 76/224 (33%), Positives = 107/224 (47%), Gaps = 31/224 (13%)
Query: 453 DVCTCELQKEVRSAR-------CSFNGDFVCGQCVCSEGWSGQTC----NCSTGSLSDIQ 501
D C C+ +++ R+ CS +G CG+C C GW G+ C +C+ + I+
Sbjct: 267 DTCECD-ERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIR 325
Query: 502 PCLREGEDKPCSGRGECQCGHCVCY--GEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSM 559
C + D PCSGRG+C+CG C CY G+ R G+ CE D+ +C G +C G CS
Sbjct: 326 KC-QGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSC 384
Query: 560 GQCVCEPGWTGPSCDCP--------LSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTD 611
G+CVCE GW G C P S C ++G +C+G+G C CG+C C + Y
Sbjct: 385 GRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYIS 444
Query: 612 ---TICEINYSAIHPGLC---EDLRSCVQCQAWGTGEKKGRTCE 649
C+ H GL + SC C+ W G CE
Sbjct: 445 GEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGW--NGNACE 486
Score = 114 bits (286), Expect = 6e-25
Identities = 66/196 (33%), Positives = 85/196 (43%), Gaps = 25/196 (12%)
Query: 452 CDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTC----NCSTGSLSDIQPCLREG 507
C CE + C+ +G CG+C C +GW G C NC Q C +
Sbjct: 91 CHEWVCETYD---GSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMC-KNS 146
Query: 508 EDKPCSGRGECQCGHCVCY---GEGRYEGQFCEYDNFQC-PRTSGFLCNDRGRCSMGQCV 563
+D CS G C CG C C G G G+FCE D+ +C + +C G+C G C
Sbjct: 147 QDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCY 206
Query: 564 CEPGWTGPSCD--CPL----SNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEIN 617
C+ GW G C+ C + S C +G IC+ RG C CG C CH D
Sbjct: 207 CKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGD------ 260
Query: 618 YSAIHPGLCE-DLRSC 632
+ IH CE D R C
Sbjct: 261 WGDIHGDTCECDERDC 276
Score = 108 bits (271), Expect = 3e-23
Identities = 74/232 (31%), Positives = 94/232 (40%), Gaps = 31/232 (13%)
Query: 441 SDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTC--NCSTGSLS 498
SDG + G C+ E + C +G CG C C GW G C C
Sbjct: 167 SDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWE 226
Query: 499 DIQPCLREGEDKPCSGRGECQCGHCVCYGE------GRYEGQFCEYDNFQC----PRTSG 548
+ C + K CS RG C CG C C+ G G CE D C R S
Sbjct: 227 SKRRC-TSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSD 285
Query: 549 FLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNA--------TCIDSNGGICNGRGHCECGR 600
C+ G+C+ G+C C+ GW G C+ P S C S+ C+GRG CECG+
Sbjct: 286 DFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGK 345
Query: 601 CHCH---QQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCE 649
C C+ + +Y T CE + CEDL V C GT CE
Sbjct: 346 CTCYPPGDRRVYGKT-CECD-----DRRCEDLDGVV-CGGHGTCSCGRCVCE 390
Score = 90.9 bits (224), Expect = 1e-17
Identities = 45/132 (34%), Positives = 57/132 (43%), Gaps = 15/132 (11%)
Query: 485 WSGQTCNCSTGSLSDIQPCLREGEDKP---CSGRGECQCGHCVCY--GEGRYEGQFCEYD 539
W G C S + C G+ C GRG C CG C+C+ G + G CE
Sbjct: 35 WPGAACRLSRAESE--RRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECH 92
Query: 540 NFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL--------SNATCIDSNGGICN 591
+ C G C G+C G+C C+ GW G +C P SN C +S IC+
Sbjct: 93 EWVCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICS 152
Query: 592 GRGHCECGRCHC 603
G C CGRC C
Sbjct: 153 NAGTCHCGRCKC 164
Score = 59.7 bits (143), Expect = 2e-08
Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 550 LCNDRGRCSMGQCVC---EPG-WTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQ 605
LC+ RGRC G C+C EPG + GP C+C C +G C G G C+CG+C C Q
Sbjct: 62 LCHGRGRCDCGVCICHVTEPGMFFGPLCEC--HEWVCETYDGSTCAGHGKCDCGKCKCDQ 119
Score = 35.4 bits (80), Expect = 0.49
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGS 496
C+ NG CG C C +GW+G C GS
Sbjct: 463 CTGNGICSCGNCECWDGWNGNACEIWLGS 491
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 101 bits (251), Expect = 7e-21
Identities = 127/555 (22%), Positives = 209/555 (37%), Gaps = 92/555 (16%)
Query: 1128 GAPQNP---NAKAAGSRKIHFNWL-PPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVEL 1183
G P P A+ +I +WL PP + + Y + YW D + + + S L
Sbjct: 510 GVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTL 569
Query: 1184 TNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAE 1242
+L P Y ++ A G G ++ + RT Q PS P + V + ST ++SW
Sbjct: 570 EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP 629
Query: 1243 PA--ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
P NG IT Y V Y V+ ++R + + ++ ++ +E E YR V+A
Sbjct: 630 PPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTE---YRVWVRA 686
Query: 1301 RNGAGWGPEREAII-------------NLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFL 1347
G GPE ++ + +P ++ + +P+ Q G+
Sbjct: 687 HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ----IR 742
Query: 1348 MYSDDVLRSPSGSQR--PSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSP 1405
Y +R +G R P + D R + + Y T +S
Sbjct: 743 GYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPE----------------ESEDYETTISG 786
Query: 1406 HVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLV 1465
P S + RS+ TT T VP PT ++
Sbjct: 787 LTPETTYSVTVAAYTTKGDGARSKPKIVTT------------------TGAVPGRPTMMI 828
Query: 1466 FSALGPTSLRVSWQEPRCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPN 1523
+ T+L + W P+ E P L GY ++Y + + ++ Q V L
Sbjct: 829 STTAMNTAL-LQWHPPK-ELPGELLGYRLQYCRADEARPNTIDFGKDDQ-HFTVTGLHKG 885
Query: 1524 HSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALS 1583
+Y+FR+ A+++ G G E E I LP S F P L T L+
Sbjct: 886 TTYIFRLAAKNRAGLGEEFEKEIRTPED---------LP-SGF-------PQNLHVTGLT 928
Query: 1584 PDSLQLSWERP--RRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVP 1641
+ +L+W+ P NG I+ Y V + + + ++R T+ GL +
Sbjct: 929 TSTTELAWDPPVLAERNGRIISYTVVFRDIN-----SQQELQNITTDTRFTLTGLKPDTT 983
Query: 1642 YKFKVQARTTEGFGP 1656
Y KV+A T++G GP
Sbjct: 984 YDIKVRAWTSKGSGP 998
Score = 96.7 bits (239), Expect = 2e-19
Identities = 140/602 (23%), Positives = 215/602 (35%), Gaps = 113/602 (18%)
Query: 1105 PDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKY 1161
P E R+ T + S PP + A+ + + W PP +G GYRV Y
Sbjct: 400 PSEAVRARTGEQAPSSPP--------RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYY 451
Query: 1162 WIQGDSESEA---HLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
A H D+ + + + +L P Y ++V A+ A G+GP S + +T Q
Sbjct: 452 TPDSRRPPNAWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQG 510
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP++P V S T QLSW P + I YE+ Y D+++ KV D
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLPPQE--RIIMYELVYWAAEDEDQ----QHKVTFDPT 564
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQ 1338
+ L E+L+ YR+ + AR+ G G + + + S P P
Sbjct: 565 SSYTL--EDLKPDTLYRFQLAARSDMGVG-----VFTPTIEARTAQSTPSAP-------- 609
Query: 1339 SGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAA 1398
V+ GS VS P +S + + T + A
Sbjct: 610 -----------PQKVMCVSMGSTTVRVS-------------WVPPPADSRNGVITQYSVA 645
Query: 1399 Y--------GTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHD 1450
Y G H+ + S + +H+ P S+ V
Sbjct: 646 YEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV---- 701
Query: 1451 SRLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELHRLN 1506
R VP P R V L T++ V W+ P + ++GY V Y L GE L
Sbjct: 702 -RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLP 760
Query: 1507 I------------PNPAQT-SVVVEDLLPNHSYVFRVRAQSQEGWG-REREGVITIESQV 1552
I P ++ + L P +Y V A + +G G R + ++T
Sbjct: 761 IIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTT---- 816
Query: 1553 HPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQ 1612
T + P P ++ T +L L W P+ G+++GY + A
Sbjct: 817 --------------TGAVPGRPTMMISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRAD 861
Query: 1613 GGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPF 1672
P T +D + TV GL + Y F++ A+ G G E E I F
Sbjct: 862 EARPNT---IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGF 918
Query: 1673 PQ 1674
PQ
Sbjct: 919 PQ 920
Score = 79.3 bits (194), Expect = 3e-14
Identities = 111/490 (22%), Positives = 184/490 (37%), Gaps = 82/490 (16%)
Query: 1186 LYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPA 1244
L P+ +Y +V A + G GP S V RT ++ PS P R+ ++S++ + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE 438
Query: 1245 ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGA 1304
E NG + Y V Y D RP K D + + +L Y V A
Sbjct: 439 EPNGLVRGYRVYY--TPDSRRPPNAWHKHNTD--AGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 1305 GWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPS 1364
G GP I Q K +P P D Q+ + D+ + S L P
Sbjct: 495 GDGPPSPTI-----QVKTQQGVPAQP----ADFQAEVESDTRIQLS--WLLPPQ------ 537
Query: 1365 VSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTH-LSPHVPHRVLSTSSTLTRDYN 1423
E ++ + + + H++T ++Y L P +R +
Sbjct: 538 -----ERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYR-----------FQ 581
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRC 1483
RS+ P ++ + ++ T P P +++ ++G T++RVSW P
Sbjct: 582 LAARSDMGVGVFTP-------TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPA 632
Query: 1484 ER---PLQGYSVEYQLLNGGE--LHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGW 1538
+ + YSV Y+ ++G + H ++ + +S + L Y VRA + G
Sbjct: 633 DSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGP 692
Query: 1539 GREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER--PRR 1596
G E V+ + P P P + L+ ++ + W+ P +
Sbjct: 693 GPESSPVLVRTDEDVPSGP----------------PRKVEVEPLNSTAVHVYWKLPVPSK 736
Query: 1597 PNGDIVGYLVTCEMAQGGGP-----------ATAFRVDGDSPESRLTVPGLSENVPYKFK 1645
+G I GY VT + G P A A +S + T+ GL+ Y
Sbjct: 737 QHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVT 796
Query: 1646 VQARTTEGFG 1655
V A TT+G G
Sbjct: 797 VAAYTTKGDG 806
Score = 59.3 bits (142), Expect = 3e-08
Identities = 59/231 (25%), Positives = 86/231 (37%), Gaps = 20/231 (8%)
Query: 1441 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1500
S+L + + +P P LV + TS+ ++W E P+ Y ++Y+ G
Sbjct: 302 SSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSE-PVTYYGIQYRAA-GT 359
Query: 1501 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1560
E + A T + L P Y FRV A + G G E V + P SP
Sbjct: 360 EGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP--- 416
Query: 1561 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF 1620
P + LS ++ + WE P PNG + GY V P A+
Sbjct: 417 -------------PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRV-YYTPDSRRPPNAW 462
Query: 1621 RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1671
TV L + Y +V A T G GP I +++Q G P
Sbjct: 463 HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPP-SPTIQVKTQQGVP 512
Score = 52.8 bits (125), Expect = 3e-06
Identities = 103/474 (21%), Positives = 166/474 (35%), Gaps = 82/474 (17%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYW------------IQGDSESE 1170
G P+ + S +H W P G+ GY+V Y IQ +E
Sbjct: 710 GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAE 769
Query: 1171 AHLLDSKVPSVELT--NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAF 1228
A + E T L P Y + V AY +G+G S T VP P +
Sbjct: 770 AQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMIS 829
Query: 1229 NVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENL 1288
+T L W P E GE+ Y + Y D+ RP + ++ + L
Sbjct: 830 TTAMNTAL-LQWHPPKELPGELLGYRLQYCRA-DEARP-----NTIDFGKDDQHFTVTGL 882
Query: 1289 RESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLM 1348
+ Y + + A+N AG G E E + T P P + + + E L
Sbjct: 883 HKGTTYIFRLAAKNRAGLGEEFEK--EIRTPEDLPSGFPQNLHVTGLTTSTTE-----LA 935
Query: 1349 YSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVP 1408
+ VL +G +++ + F S L +TT + T L P
Sbjct: 936 WDPPVLAERNG-----------RIISYTVVFRDINSQQELQNITTDTRFTL-TGLKPDTT 983
Query: 1409 HRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSA 1468
+ + + T S S S T+P + V + + R+ A +
Sbjct: 984 YDIKVRAWT---SKGSGPLSPSIQSRTMP-----VEQVFAKNFRVAAAM----------- 1024
Query: 1469 LGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVF 1528
TS+ +SW+ P + +V +++L G+ ++ + + ++ DL PN Y F
Sbjct: 1025 --KTSVLLSWEVPDSYKS----AVPFKILYNGQSVEVDGHSMRK---LIADLQPNTEYSF 1075
Query: 1529 RVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSA------FTLSTPSAPGP 1576
+ + G + I + P PLP SA F LS P P
Sbjct: 1076 VLMNRGSSAGGLQHLVSIRTAPDLLPHK---PLPASAYIEDGRFDLSMPHVQDP 1126
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 100 bits (249), Expect = 1e-20
Identities = 142/546 (26%), Positives = 210/546 (38%), Gaps = 77/546 (14%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWI---QGDSESEAHLLDSKVPSVELT 1184
G P N A+A I +W PP + + +KY + +GD E S +
Sbjct: 513 GQPMNLRAEARSETSITLSWSPPRQESI---IKYELLFREGDHGREVGRTFDPTTSYVVE 569
Query: 1185 NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAEP 1243
+L P +Y ++ A QG G ++ +V RT Q PS P + V V ST +SW P
Sbjct: 570 DLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPP 629
Query: 1244 A-ET-NGEITAYEVCYG-LVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
ET NG + Y V Y L ++D P K+V P +L+E L + YR T A
Sbjct: 630 PPETHNGALVGYSVRYRPLGSEDPEP----KEVNGIPPTTTQILLEALEKWTQYRITTVA 685
Query: 1301 RNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPS-G 1359
G GPE P+ + D+P + E + RSP+ G
Sbjct: 686 HTEVGPGPE-----------SSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPG 734
Query: 1360 SQRPSVSDDTEHLVNGRMDFA-FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTL 1418
Q + H V RM+ A G M + T+L P + + + T+
Sbjct: 735 RQHGQIRGYQVHYV--RMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTM 792
Query: 1419 TRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSW 1478
D + + P+ T +V R T V TP SL W
Sbjct: 793 KGD----------GARSKPKVVVTKGAVL---GRPTLSVQQTP---------EGSLLARW 830
Query: 1479 QEP--RCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQE 1536
+ P E + GY +++ + L L P P++ + +YVFR+ A+S+
Sbjct: 831 EPPAGTAEDQVLGYRLQFGREDSTPLATLEFP-PSEDRYTASGVHKGATYVFRLAARSRG 889
Query: 1537 GWGREREGVITIESQV---HPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER 1593
G G E V++I HPQ + G+A + G ++ L P
Sbjct: 890 GLGEEAAEVLSIPEDTPRGHPQ--ILEAAGNA-------SAGTVLLRWLPP--------V 932
Query: 1594 PRRPNGDIVGYLVTCEMAQGGGPATAFRVDG---DSPESRLTVPGLSENVPYKFKVQART 1650
P NG IV Y V A GPA + E+ LT+ GL + Y +V+A T
Sbjct: 933 PAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHT 992
Query: 1651 TEGFGP 1656
G GP
Sbjct: 993 RRGPGP 998
Score = 89.4 bits (220), Expect = 3e-17
Identities = 130/571 (22%), Positives = 217/571 (38%), Gaps = 88/571 (15%)
Query: 1129 APQNPNAKAAGSRKIHFNW---LPPSGKPMGYRVKYWIQGD---SESEAHLLDSKVPSVE 1182
AP+N A+ + + W + P+G GYRV Y ++ + + H +D + +
Sbjct: 416 APRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTT- 474
Query: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAE 1242
+ +L Y ++V A+ + G+GP S + +T Q VP +P L S T LSW+
Sbjct: 475 VGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSP 534
Query: 1243 PAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARN 1302
P + + I YE+ + D R +G ++E+L+ + Y + + AR+
Sbjct: 535 PRQES--IIKYELLFR-EGDHGREVGRTFDPTTS------YVVEDLKPNTEYAFRLAARS 585
Query: 1303 GAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDV----LRSPS 1358
G G ++ T +P + P D+ V +S S+ + L S
Sbjct: 586 PQGLGAFTP-VVRQRTLQSKPSAPP--QDVKCVSVRSTAILVSWRPPPPETHNGALVGYS 642
Query: 1359 GSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTL 1418
RP S+D E P N + TT ++L +
Sbjct: 643 VRYRPLGSEDPE-----------PKEVNGIPPTTT----------------QILLEALEK 675
Query: 1419 TRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFS-ALGPTSLRVS 1477
Y T + H+ P S+ V + + VP P R V + AL T++RV
Sbjct: 676 WTQYRITTVA---HTEVGPGPESSPVVVRTDED-----VPSAPPRKVEAEALNATAIRVL 727
Query: 1478 WQEP---RCERPLQGYSVEYQLLNGGELHR----LNIPNPAQTSVVVEDLLPNHSYVFRV 1530
W+ P R ++GY V Y + G E ++ +V+ +L P +Y V
Sbjct: 728 WRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITV 787
Query: 1531 RAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLS 1590
A + +G G + + + P TLS P SL
Sbjct: 788 AAYTMKGDGARSKPKVVVTKGAVLGRP---------TLSVQQTP---------EGSLLAR 829
Query: 1591 WERPRRPNGD-IVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQAR 1649
WE P D ++GY + AT ++ E R T G+ + Y F++ AR
Sbjct: 830 WEPPAGTAEDQVLGYRLQFGREDSTPLAT---LEFPPSEDRYTASGVHKGATYVFRLAAR 886
Query: 1650 TTEGFGPEREGIITIESQDGGPFPQLGSRAG 1680
+ G G E +++I PQ+ AG
Sbjct: 887 SRGGLGEEAAEVLSIPEDTPRGHPQILEAAG 917
Score = 79.0 bits (193), Expect = 4e-14
Identities = 127/545 (23%), Positives = 199/545 (36%), Gaps = 87/545 (15%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLL-DSKVPSVELTNLY 1187
AP P + I W + P+ Y V + + + D + L
Sbjct: 321 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 380
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAET 1246
P +YE+ V A + G+GP S V RT ++ P S P + ++S+T + W EP E
Sbjct: 381 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 440
Query: 1247 NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
NG I Y V Y + + P+G +K VD+ + + + +L E + Y V A G
Sbjct: 441 NGLIRGYRVYYTM--EPEHPVGNWQKHNVDD--SLLTTVGSLLEDETYTVRVLAFTSVGD 496
Query: 1307 GPEREAIINLATQ---PKRPMSI--PIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQ 1361
GP + I + TQ P +PM++ + I + S +S + Y G +
Sbjct: 497 GPLSDP-IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGRE 555
Query: 1362 RPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRD 1421
D T V + +T R+ S G +P V R L
Sbjct: 556 VGRTFDPTTSYVVEDL----KPNTEYAFRLAARSPQGLGA-FTPVVRQRTL--------- 601
Query: 1422 YNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEP 1481
S + P+D ++ S+ ++ VSW+ P
Sbjct: 602 --------QSKPSAPPQDVKCVSVRST------------------------AILVSWRPP 629
Query: 1482 RCER---PLQGYSVEYQLLNG--GELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQE 1536
E L GYSV Y+ L E +N P T +++E L Y A ++
Sbjct: 630 PPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEV 689
Query: 1537 GWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPR- 1595
G G E V+ + P +P P + AL+ ++++ W P
Sbjct: 690 GPGPESSPVVVRTDEDVPSAP----------------PRKVEAEALNATAIRVLWRSPAP 733
Query: 1596 -RPNGDIVGY---LVTCEMAQGGGPATAFRVD-GDSPESRLTVPGLSENVPYKFKVQART 1650
R +G I GY V E A+ GP V D+ E + + L Y V A T
Sbjct: 734 GRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQE--MVITNLQPETAYSITVAAYT 791
Query: 1651 TEGFG 1655
+G G
Sbjct: 792 MKGDG 796
Score = 53.9 bits (128), Expect = 1e-06
Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1457 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1516
+P P + + TS+ ++W + P+ Y +EY+ + +++ + T
Sbjct: 318 LPKAPGTPMVTENTATSITITWDSGNPD-PVSYYVIEYKSKSQDGPYQIK-EDITTTRYS 375
Query: 1517 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1576
+ L PN Y V A + G G E V+T + P S AP
Sbjct: 376 IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPAS----------------APRN 419
Query: 1577 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1634
+ LS ++ + WE P PNG I GY V T E G VD +S LT
Sbjct: 420 VQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD----DSLLTTV 475
Query: 1635 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1679
G L E+ Y +V A T+ G GP + I +++Q G P + RA
Sbjct: 476 GSLLEDETYTVRVLAFTSVGDGPLSDP-IQVKTQQGVPGQPMNLRA 520
Score = 43.5 bits (101), Expect = 0.002
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 1569 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGY-LVTCEMAQGGGPATAFRVDGDSP 1627
S P APG + T + S+ ++W+ N D V Y ++ + GP +++ D
Sbjct: 317 SLPKAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEYKSKSQDGP---YQIKEDIT 370
Query: 1628 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1687
+R ++ GLS N Y+ V A + G GP E ++T + G P R +Q
Sbjct: 371 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVT---RTGEQAPASAPR------NVQ 421
Query: 1688 SEYSSITTTHTSATEPFLVDGLTLG 1712
+ S TT EP +GL G
Sbjct: 422 ARMLSATTMIVQWEEPVEPNGLIRG 446
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/186 (25%), Positives = 68/186 (36%), Gaps = 15/186 (8%)
Query: 1089 GAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWL 1148
G H G + + R L + + P G + +AG+ + WL
Sbjct: 872 GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGT--VLLRWL 929
Query: 1149 PP-SGKPMGYRVKYWIQGDSES------EAHLLDSKVPSVE----LTNLYPYCDYEMKVC 1197
PP + G VKY + E L + P E L L P Y+++V
Sbjct: 930 PPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVR 989
Query: 1198 AYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCY 1257
A+ +G GP+S V RT P ++ T LSW P N T Y++ Y
Sbjct: 990 AHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSP-TPYKIQY 1048
Query: 1258 -GLVND 1262
GL D
Sbjct: 1049 NGLTLD 1054
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 100 bits (249), Expect = 1e-20
Identities = 127/555 (22%), Positives = 207/555 (37%), Gaps = 101/555 (18%)
Query: 1128 GAPQNP---NAKAAGSRKIHFNWL-PPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVEL 1183
G P P A+ +I +WL PP + + Y + YW D + + + S L
Sbjct: 510 GVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTL 569
Query: 1184 TNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAE 1242
+L P Y ++ A G G ++ + RT Q PS P + V + ST ++SW
Sbjct: 570 EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP 629
Query: 1243 PA--ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
P NG IT Y V Y V+ ++R + + ++ ++ +E E YR V+A
Sbjct: 630 PPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTE---YRVWVRA 686
Query: 1301 RNGAGWGPEREAII-------------NLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFL 1347
G GPE ++ + +P ++ + +P+ Q G+
Sbjct: 687 HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ----IR 742
Query: 1348 MYSDDVLRSPSGSQR--PSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSP 1405
Y +R +G R P + D A A T +S
Sbjct: 743 GYQVTYVRLENGEPRGLPIIQD-------------------------VMLAEAQETTISG 777
Query: 1406 HVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLV 1465
P S + RS+ TT T VP PT ++
Sbjct: 778 LTPETTYSVTVAAYTTKGDGARSKPKIVTT------------------TGAVPGRPTMMI 819
Query: 1466 FSALGPTSLRVSWQEPRCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPN 1523
+ T+L + W P+ E P L GY ++Y + + ++ Q V L
Sbjct: 820 STTAMNTAL-LQWHPPK-ELPGELLGYRLQYCRADEARPNTIDFGKDDQ-HFTVTGLHKG 876
Query: 1524 HSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALS 1583
+Y+FR+ A+++ G G E E I LP S F P L T L+
Sbjct: 877 TTYIFRLAAKNRAGLGEEFEKEIRTPED---------LP-SGF-------PQNLHVTGLT 919
Query: 1584 PDSLQLSWERP--RRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVP 1641
+ +L+W+ P NG I+ Y V + + + ++R T+ GL +
Sbjct: 920 TSTTELAWDPPVLAERNGRIISYTVVFRDIN-----SQQELQNITTDTRFTLTGLKPDTT 974
Query: 1642 YKFKVQARTTEGFGP 1656
Y KV+A T++G GP
Sbjct: 975 YDIKVRAWTSKGSGP 989
Score = 99.8 bits (247), Expect = 2e-20
Identities = 139/593 (23%), Positives = 213/593 (35%), Gaps = 104/593 (17%)
Query: 1105 PDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKY 1161
P E R+ T + S PP + A+ + + W PP +G GYRV Y
Sbjct: 400 PSEAVRARTGEQAPSSPP--------RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYY 451
Query: 1162 WIQGDSESEA---HLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
A H D+ + + + +L P Y ++V A+ A G+GP S + +T Q
Sbjct: 452 TPDSRRPPNAWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQG 510
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP++P V S T QLSW P + I YE+ Y D+++ KV D
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLPPQE--RIIMYELVYWAAEDEDQ----QHKVTFDPT 564
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQ 1338
+ L E+L+ YR+ + AR+ G G + + + S P P
Sbjct: 565 SSYTL--EDLKPDTLYRFQLAARSDMGVG-----VFTPTIEARTAQSTPSAP-------- 609
Query: 1339 SGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAA 1398
V+ GS VS P +S + + T + A
Sbjct: 610 -----------PQKVMCVSMGSTTVRVS-------------WVPPPADSRNGVITQYSVA 645
Query: 1399 Y--------GTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHD 1450
Y G H+ + S + +H+ P S+ V
Sbjct: 646 YEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV---- 701
Query: 1451 SRLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELHRLN 1506
R VP P R V L T++ V W+ P + ++GY V Y L GE L
Sbjct: 702 -RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLP 760
Query: 1507 IPNPAQTS----VVVEDLLPNHSYVFRVRAQSQEGWG-REREGVITIESQVHPQSPLCPL 1561
I + + L P +Y V A + +G G R + ++T
Sbjct: 761 IIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTT------------- 807
Query: 1562 PGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFR 1621
T + P P ++ T +L L W P+ G+++GY + A P T
Sbjct: 808 -----TGAVPGRPTMMISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRADEARPNT--- 858
Query: 1622 VDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQ 1674
+D + TV GL + Y F++ A+ G G E E I FPQ
Sbjct: 859 IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQ 911
Score = 77.8 bits (190), Expect = 9e-14
Identities = 109/482 (22%), Positives = 182/482 (37%), Gaps = 75/482 (15%)
Query: 1186 LYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPA 1244
L P+ +Y +V A + G GP S V RT ++ PS P R+ ++S++ + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE 438
Query: 1245 ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGA 1304
E NG + Y V Y D RP K D + + +L Y V A
Sbjct: 439 EPNGLVRGYRVYY--TPDSRRPPNAWHKHNTD--AGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 1305 GWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPS 1364
G GP I Q K +P P D Q+ + D+ + S L P
Sbjct: 495 GDGPPSPTI-----QVKTQQGVPAQP----ADFQAEVESDTRIQLS--WLLPPQ------ 537
Query: 1365 VSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTH-LSPHVPHRVLSTSSTLTRDYN 1423
E ++ + + + H++T ++Y L P +R +
Sbjct: 538 -----ERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYR-----------FQ 581
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRC 1483
RS+ P ++ + ++ T P P +++ ++G T++RVSW P
Sbjct: 582 LAARSDMGVGVFTP-------TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPA 632
Query: 1484 ER---PLQGYSVEYQLLNGGE--LHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGW 1538
+ + YSV Y+ ++G + H ++ + +S + L Y VRA + G
Sbjct: 633 DSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGP 692
Query: 1539 GREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER--PRR 1596
G E V+ + P P P + L+ ++ + W+ P +
Sbjct: 693 GPESSPVLVRTDEDVPSGP----------------PRKVEVEPLNSTAVHVYWKLPVPSK 736
Query: 1597 PNGDIVGYLVTCEMAQGGGPATAFRVDGD---SPESRLTVPGLSENVPYKFKVQARTTEG 1653
+G I GY VT + G P + D + T+ GL+ Y V A TT+G
Sbjct: 737 QHGQIRGYQVTYVRLENGEP-RGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKG 795
Query: 1654 FG 1655
G
Sbjct: 796 DG 797
Score = 59.3 bits (142), Expect = 3e-08
Identities = 59/231 (25%), Positives = 86/231 (37%), Gaps = 20/231 (8%)
Query: 1441 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1500
S+L + + +P P LV + TS+ ++W E P+ Y ++Y+ G
Sbjct: 302 SSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSE-PVTYYGIQYRAA-GT 359
Query: 1501 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1560
E + A T + L P Y FRV A + G G E V + P SP
Sbjct: 360 EGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP--- 416
Query: 1561 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF 1620
P + LS ++ + WE P PNG + GY V P A+
Sbjct: 417 -------------PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRV-YYTPDSRRPPNAW 462
Query: 1621 RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1671
TV L + Y +V A T G GP I +++Q G P
Sbjct: 463 HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPP-SPTIQVKTQQGVP 512
Score = 55.5 bits (132), Expect = 5e-07
Identities = 98/465 (21%), Positives = 166/465 (35%), Gaps = 73/465 (15%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEA-----HLLDSK 1177
G P+ + S +H W P G+ GY+V Y + E ++ ++
Sbjct: 710 GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAE 769
Query: 1178 VPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQ 1237
++ L P Y + V AY +G+G S T VP P + +T
Sbjct: 770 AQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTAL- 828
Query: 1238 LSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYT 1297
L W P E GE+ Y + Y D+ RP + ++ + L + Y +
Sbjct: 829 LQWHPPKELPGELLGYRLQYCRA-DEARP-----NTIDFGKDDQHFTVTGLHKGTTYIFR 882
Query: 1298 VKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSP 1357
+ A+N AG G E E + T P P + + + E L + VL
Sbjct: 883 LAAKNRAGLGEEFEK--EIRTPEDLPSGFPQNLHVTGLTTSTTE-----LAWDPPVLAER 935
Query: 1358 SGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSST 1417
+G +++ + F S L +TT + T L P + + + T
Sbjct: 936 NG-----------RIISYTVVFRDINSQQELQNITTDTRFTL-TGLKPDTTYDIKVRAWT 983
Query: 1418 LTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVS 1477
S S S T+P + V + + R+ A + TS+ +S
Sbjct: 984 ---SKGSGPLSPSIQSRTMP-----VEQVFAKNFRVAAAM-------------KTSVLLS 1022
Query: 1478 WQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEG 1537
W+ P + +V +++L G+ ++ + + ++ DL PN Y F + +
Sbjct: 1023 WEVPDSYKS----AVPFKILYNGQSVEVDGHSMRK---LIADLQPNTEYSFVLMNRGSSA 1075
Query: 1538 WGREREGVITIESQVHPQSPLCPLPGSA------FTLSTPSAPGP 1576
G + I + P PLP SA F LS P P
Sbjct: 1076 GGLQHLVSIRTAPDLLPHK---PLPASAYIEDGRFDLSMPHVQDP 1117
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 98.2 bits (243), Expect = 6e-20
Identities = 143/555 (25%), Positives = 212/555 (38%), Gaps = 86/555 (15%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWI---QGDSESEAHLLDSKVPSVELT 1184
G P N A+A I +W PP + + +KY + +GD E S +
Sbjct: 526 GQPMNLRAEARSETSITLSWSPPRQESI---IKYELLFREGDHGREVGRTFDPTTSYVVE 582
Query: 1185 NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAEP 1243
+L P +Y ++ A QG G ++ +V RT Q PS P + V V ST +SW P
Sbjct: 583 DLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPP 642
Query: 1244 A-ET-NGEITAYEVCYG-LVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
ET NG + Y V Y L ++D P K+V P +L+E L + YR T A
Sbjct: 643 PPETHNGALVGYSVRYRPLGSEDPEP----KEVNGIPPTTTQILLEALEKWTQYRITTVA 698
Query: 1301 RNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPS-G 1359
G GPE P+ + D+P + E + RSP+ G
Sbjct: 699 HTEVGPGPE-----------SSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPG 747
Query: 1360 SQRPSVSDDTEHLVNGRMDFAFPGSTNSLH-------RMTTTSAAAYG---THLSPHVPH 1409
Q + H V RM+ A + + T A Y T+L P +
Sbjct: 748 RQHGQIRGYQVHYV--RMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAY 805
Query: 1410 RVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSAL 1469
+ + T+ D + + P+ T +V R T V TP
Sbjct: 806 SITVAAYTMKGD----------GARSKPKVVVTKGAVL---GRPTLSVQQTP-------- 844
Query: 1470 GPTSLRVSWQEP--RCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYV 1527
SL W+ P E + GY +++ + L L P P++ + +YV
Sbjct: 845 -EGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFP-PSEDRYTASGVHKGATYV 902
Query: 1528 FRVRAQSQEGWGREREGVITIESQV---HPQSPLCPLPGSAFTLSTPSAPGPLVFTALSP 1584
FR+ A+S+ G G E V++I HPQ + G+A + G ++ L P
Sbjct: 903 FRLAARSRGGLGEEAAEVLSIPEDTPRGHPQ--ILEAAGNA-------SAGTVLLRWLPP 953
Query: 1585 DSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDG---DSPESRLTVPGLSENVP 1641
P NG IV Y V A GPA + E+ LT+ GL +
Sbjct: 954 --------VPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTA 1005
Query: 1642 YKFKVQARTTEGFGP 1656
Y +V+A T G GP
Sbjct: 1006 YDLQVRAHTRRGPGP 1020
Score = 90.1 bits (222), Expect = 2e-17
Identities = 131/580 (22%), Positives = 219/580 (37%), Gaps = 97/580 (16%)
Query: 1129 APQNPNAKAAGSRKIHFNW---LPPSGKPMGYRVKYWIQGD---SESEAHLLDSKVPSVE 1182
AP+N A+ + + W + P+G GYRV Y ++ + + H +D + +
Sbjct: 429 APRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTT- 487
Query: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAE 1242
+ +L Y ++V A+ + G+GP S + +T Q VP +P L S T LSW+
Sbjct: 488 VGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSP 547
Query: 1243 PAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARN 1302
P + + I YE+ + D R +G ++E+L+ + Y + + AR+
Sbjct: 548 PRQES--IIKYELLFR-EGDHGREVGRTFDPTTS------YVVEDLKPNTEYAFRLAARS 598
Query: 1303 GAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDV----LRSPS 1358
G G ++ T +P + P D+ V +S S+ + L S
Sbjct: 599 PQGLGAFTP-VVRQRTLQSKPSAPP--QDVKCVSVRSTAILVSWRPPPPETHNGALVGYS 655
Query: 1359 GSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTL 1418
RP S+D E P N + TT ++L +
Sbjct: 656 VRYRPLGSEDPE-----------PKEVNGIPPTTT----------------QILLEALEK 688
Query: 1419 TRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFS-ALGPTSLRVS 1477
Y T + H+ P S+ V + + VP P R V + AL T++RV
Sbjct: 689 WTQYRITTVA---HTEVGPGPESSPVVVRTDED-----VPSAPPRKVEAEALNATAIRVL 740
Query: 1478 WQEP---RCERPLQGYSVEYQLLNGGELH-------------RLNIPNPAQTSVVVEDLL 1521
W+ P R ++GY V Y + G E + + A+ +V+ +L
Sbjct: 741 WRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQ 800
Query: 1522 PNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTA 1581
P +Y V A + +G G + + + P TLS P
Sbjct: 801 PETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---------TLSVQQTP------- 844
Query: 1582 LSPDSLQLSWERPRRPNGD-IVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENV 1640
SL WE P D ++GY + AT ++ E R T G+ +
Sbjct: 845 --EGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLAT---LEFPPSEDRYTASGVHKGA 899
Query: 1641 PYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAG 1680
Y F++ AR+ G G E +++I PQ+ AG
Sbjct: 900 TYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAG 939
Score = 82.0 bits (201), Expect = 5e-15
Identities = 128/552 (23%), Positives = 200/552 (36%), Gaps = 92/552 (16%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLL-DSKVPSVELTNLY 1187
AP P + I W + P+ Y V + + + D + L
Sbjct: 334 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 393
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAET 1246
P +YE+ V A + G+GP S V RT ++ P S P + ++S+T + W EP E
Sbjct: 394 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 453
Query: 1247 NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
NG I Y V Y + + P+G +K VD+ + + + +L E + Y V A G
Sbjct: 454 NGLIRGYRVYYTM--EPEHPVGNWQKHNVDD--SLLTTVGSLLEDETYTVRVLAFTSVGD 509
Query: 1307 GPEREAIINLATQ---PKRPMSI--PIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQ 1361
GP + I + TQ P +PM++ + I + S +S + Y G +
Sbjct: 510 GPLSDP-IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGRE 568
Query: 1362 RPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRD 1421
D T V + +T R+ S G +P V R L
Sbjct: 569 VGRTFDPTTSYVVEDL----KPNTEYAFRLAARSPQGLGA-FTPVVRQRTL--------- 614
Query: 1422 YNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEP 1481
S + P+D ++ S+ ++ VSW+ P
Sbjct: 615 --------QSKPSAPPQDVKCVSVRST------------------------AILVSWRPP 642
Query: 1482 RCER---PLQGYSVEYQLLNG--GELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQE 1536
E L GYSV Y+ L E +N P T +++E L Y A ++
Sbjct: 643 PPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEV 702
Query: 1537 GWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPR- 1595
G G E V+ + P +P P + AL+ ++++ W P
Sbjct: 703 GPGPESSPVVVRTDEDVPSAP----------------PRKVEAEALNATAIRVLWRSPAP 746
Query: 1596 -RPNGDIVGY---LVTCEMAQGGGP--------ATAFRVDGDSPESRLTVPGLSENVPYK 1643
R +G I GY V E A+ GP A A D+ E + + L Y
Sbjct: 747 GRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYS 806
Query: 1644 FKVQARTTEGFG 1655
V A T +G G
Sbjct: 807 ITVAAYTMKGDG 818
Score = 53.9 bits (128), Expect = 1e-06
Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1457 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1516
+P P + + TS+ ++W + P+ Y +EY+ + +++ + T
Sbjct: 331 LPKAPGTPMVTENTATSITITWDSGNPD-PVSYYVIEYKSKSQDGPYQIK-EDITTTRYS 388
Query: 1517 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1576
+ L PN Y V A + G G E V+T + P S AP
Sbjct: 389 IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPAS----------------APRN 432
Query: 1577 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1634
+ LS ++ + WE P PNG I GY V T E G VD +S LT
Sbjct: 433 VQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD----DSLLTTV 488
Query: 1635 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1679
G L E+ Y +V A T+ G GP + I +++Q G P + RA
Sbjct: 489 GSLLEDETYTVRVLAFTSVGDGPLSDP-IQVKTQQGVPGQPMNLRA 533
Score = 43.5 bits (101), Expect = 0.002
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 1569 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGY-LVTCEMAQGGGPATAFRVDGDSP 1627
S P APG + T + S+ ++W+ N D V Y ++ + GP +++ D
Sbjct: 330 SLPKAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEYKSKSQDGP---YQIKEDIT 383
Query: 1628 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1687
+R ++ GLS N Y+ V A + G GP E ++T + G P R +Q
Sbjct: 384 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVT---RTGEQAPASAPR------NVQ 434
Query: 1688 SEYSSITTTHTSATEPFLVDGLTLG 1712
+ S TT EP +GL G
Sbjct: 435 ARMLSATTMIVQWEEPVEPNGLIRG 459
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/186 (25%), Positives = 68/186 (36%), Gaps = 15/186 (8%)
Query: 1089 GAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWL 1148
G H G + + R L + + P G + +AG+ + WL
Sbjct: 894 GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGT--VLLRWL 951
Query: 1149 PP-SGKPMGYRVKYWIQGDSES------EAHLLDSKVPSVE----LTNLYPYCDYEMKVC 1197
PP + G VKY + E L + P E L L P Y+++V
Sbjct: 952 PPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVR 1011
Query: 1198 AYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCY 1257
A+ +G GP+S V RT P ++ T LSW P N T Y++ Y
Sbjct: 1012 AHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSP-TPYKIQY 1070
Query: 1258 -GLVND 1262
GL D
Sbjct: 1071 NGLTLD 1076
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 97.4 bits (241), Expect = 1e-19
Identities = 67/208 (32%), Positives = 98/208 (47%), Gaps = 17/208 (8%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAH---LLDSKVPS 1180
APQN + ++ W PP +G GY++ YW + DS++E +L P
Sbjct: 1704 APQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYW-EADSQNETEKMKVLFLPEPV 1762
Query: 1181 VELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
V L NL + Y + + A+ A G+GP S RTHQ P P LAF+ ++ST +SW
Sbjct: 1763 VRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSW 1822
Query: 1241 AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVL---VDNPKNRMLLIENLRESQPYRYT 1297
EPA NG + Y V Y + P+ + KV+ V R L + +L + Y +
Sbjct: 1823 GEPAAANGILQGYRVVY----EPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFR 1878
Query: 1298 VKARNGAGWGPEREAIINLATQPKRPMS 1325
V+AR +GPE +A I P S
Sbjct: 1879 VQART-ITYGPELQANITAGPAEGSPGS 1905
Score = 87.0 bits (214), Expect = 1e-16
Identities = 121/563 (21%), Positives = 203/563 (36%), Gaps = 82/563 (14%)
Query: 1129 APQNPNAKAAGSRKIHFNWLP-----PSGKPMGYRVKYWIQG-DSESEAHLL-DSKVPSV 1181
AP+N +A+A S +I W +G +GY++ + + D E +H++ + S
Sbjct: 1279 APENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSA 1338
Query: 1182 ELTNLYPYCDYEMKVCAYGAQGEG-PYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
L L + YE++V A+ G G P + L+ RT + P P RL F V T ++ W
Sbjct: 1339 LLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVW 1398
Query: 1241 AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
P E NG I Y++ Y L + ++ R +L Y + + A
Sbjct: 1399 QPPEEPNGIILGYQIAYRLASSSPHTFTTVEV----GATVRQFTATDLAPESAYIFRLSA 1454
Query: 1301 RNGAGWGPEREAIINLATQPKRPMSIP----IIPDIPIVDAQ------SGEDYDSFLMYS 1350
+ GWG EA + T KR P ++P + G D S + Y
Sbjct: 1455 KTRQGWGEPLEATV--ITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYF 1512
Query: 1351 DDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPH- 1409
+R + + S H + A L P +
Sbjct: 1513 TMQVRELPRGEWQTYSSSISH----------------------EATACVVDRLRPFTSYK 1550
Query: 1410 -RVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSA 1468
R+ +T+ D++S T + +TL V + P T
Sbjct: 1551 LRLKATNDIGDSDFSSETEA-----------VTTLQDVPGEPPGSVSATPHT-------- 1591
Query: 1469 LGPTSLRVSWQEPRCER---PLQGYSV-----EYQLLNGGELHRLNIPNPAQTSVVVEDL 1520
+S+ + WQ PR E LQGY + EY+ +G E L P + +
Sbjct: 1592 --TSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSS 1649
Query: 1521 LP--NHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLV 1578
N S + + R E ++T + + P+ + AP +
Sbjct: 1650 FKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQ 1709
Query: 1579 FTALSPDSLQLSWE--RPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1636
T L+ L+++W+ P NG+I GY + A +V PE + + L
Sbjct: 1710 VTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKV-LFLPEPVVRLKNL 1768
Query: 1637 SENVPYKFKVQARTTEGFGPERE 1659
+ + Y + A G GP+ +
Sbjct: 1769 TSHTKYLVSISAFNAAGDGPKSD 1791
Score = 82.4 bits (202), Expect = 4e-15
Identities = 129/577 (22%), Positives = 209/577 (36%), Gaps = 99/577 (17%)
Query: 1123 PHGDLGAPQNPNAKAAGSRKIHFNWLPP--SGKPMGYRVKYWIQGDSESEAHL--LDSKV 1178
PH +PN+ + S + +W+ P P+ Y + + +S + HL + ++
Sbjct: 668 PHSPQNLLVSPNS--SHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEM 725
Query: 1179 PSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVS-CRTHQEVPSEPGRLAFNVVSSTVTQ 1237
V ++ L P Y+ +VCA G G YS+ S +E PS P + N+V+S T
Sbjct: 726 TGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPK---NIVASGRTN 782
Query: 1238 LS----WAEPAET--NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRES 1291
S W P ET NG + Y + Y L G ++ + +P+ L+ +L
Sbjct: 783 QSIMVQWQPPPETEHNGVLRGYILRYRLAGLP----GEYQQRNITSPEVNYCLVTDLIIW 838
Query: 1292 QPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSD 1351
Y V A NGAG G A+ Q +P P
Sbjct: 839 TQYEIQVAAYNGAGLGVFSRAVTEYTLQ-----GVPTAP--------------------- 872
Query: 1352 DVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRV 1411
P Q +V+ T + F N +++ A A P V
Sbjct: 873 -----PQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADA---------PEAV 918
Query: 1412 LSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT--------- 1462
T T+ D++ + H H T L + + TSV + G P TP
Sbjct: 919 --TVVTIAPDFHGV---HHGHITNLKKFTAYFTSVLCFTTP-GDGPPSTPQLVWTQEDKP 972
Query: 1463 ----RLVFSALGPTSLRVSWQEPRCERP-LQGYSVEYQLLNGGELHRLNIPNPAQTSVVV 1517
L F+ + TSL+VSWQEP + + GY + +++ + + N +
Sbjct: 973 GAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKI 1032
Query: 1518 EDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPL 1577
+ L +Y V A + G G TI S V P P AP L
Sbjct: 1033 QGLSSLTTYTIDVAAVTAVGTGLVTSS--TISSGVPP--------------DLPGAPSNL 1076
Query: 1578 VFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGP---ATAFRVDGDSPESRLTVP 1634
V + +SP S L + I ++V ++ G T + + + L +P
Sbjct: 1077 VISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIP 1136
Query: 1635 GLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1671
L+ Y+F+++ G P I++ P
Sbjct: 1137 NLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPP 1173
Score = 75.5 bits (184), Expect = 4e-13
Identities = 135/609 (22%), Positives = 222/609 (36%), Gaps = 108/609 (17%)
Query: 1148 LPPSGKPMGYRVKYWIQGDSESE-AHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGP 1206
L +G GY++ + + G ++S H L+S ++ L Y + V A A G G
Sbjct: 996 LEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGL 1055
Query: 1207 Y-SSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAY--EVCYGLVNDD 1263
SS +S ++P P L + +S L + + I+ + E G + D+
Sbjct: 1056 VTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDE 1115
Query: 1264 NRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAG---WGPEREAIINLATQP 1320
+ ++ + P +ML I NL YR+ +K N G + P I L P
Sbjct: 1116 EEWVTLYEEE--NEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPP 1173
Query: 1321 K-RPMSIPI---------IPDIPIVDAQSGEDYDSF---LMYSDDVLRSPSGSQRPSVSD 1367
P S+ + + +P+ D+Q + +S + Y L+S + +Q VSD
Sbjct: 1174 DVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQ--VVSD 1231
Query: 1368 DTEH------------------------------LVNGRMDFAFPGSTN---SLHRMTTT 1394
E +V GR + P + S +++T
Sbjct: 1232 RLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSST 1291
Query: 1395 SAAAYGTHLSPH------VPHRVLSTSSTLTRDYNS-LTRSEHSHSTTLP--RDYSTLTS 1445
T + + +++L + L + S + R H+ S L R +
Sbjct: 1292 QILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYEL 1351
Query: 1446 VSSHDSRLTAGVPDTP--------------TRLVFSALGPTSLRVSWQEPRCERP---LQ 1488
+R+ GVP TP RLVF + TS+R+ WQ P E P +
Sbjct: 1352 QVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPP--EEPNGIIL 1409
Query: 1489 GYSVEYQLLNGGELHRLNIPNPAQT--SVVVEDLLPNHSYVFRVRAQSQEGWGREREG-V 1545
GY + Y+L + H T DL P +Y+FR+ A++++GWG E V
Sbjct: 1410 GYQIAYRLASSSP-HTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATV 1468
Query: 1546 ITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYL 1605
IT E + P P L P A ++ SL+L W P + Y
Sbjct: 1469 ITTEKRERPAPPR--------ELLVPQA-------EVTARSLRLQWV-PGSDGASPIRYF 1512
Query: 1606 VTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEG---FGPEREGII 1662
G + + V L YK +++A G F E E +
Sbjct: 1513 TMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVT 1572
Query: 1663 TIESQDGGP 1671
T++ G P
Sbjct: 1573 TLQDVPGEP 1581
Score = 73.6 bits (179), Expect = 2e-12
Identities = 117/507 (23%), Positives = 204/507 (40%), Gaps = 95/507 (18%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPP-----SGKP--MGYRVKYWIQGDSESEAH---LLDSKV 1178
AP + + A + W+P +G P +GYR+KYW + D +S A + D
Sbjct: 1176 APTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYW-RSDLQSSAVAQVVSDRLE 1234
Query: 1179 PSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQ 1237
+ L + +YE+++ A+ A G GP+S +V RT + VPS P ++ VSST
Sbjct: 1235 REFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQIL 1294
Query: 1238 LSWAEPAE--TNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
L+W E NG I Y++ + + D P + +V + L+ LR+ Y
Sbjct: 1295 LTWTSVPEQDQNGLILGYKILFRAKDLDPEP----RSHIVRGNHTQSALLAGLRKFVLYE 1350
Query: 1296 YTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLR 1355
V A G G +I T+ P P + +V + + S ++
Sbjct: 1351 LQVLAFTRIGNGVPSTPLILERTKDDAPG-----PPVRLV-------FPEVRLTSVRIVW 1398
Query: 1356 SPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAA-----YGTHLSPHVPHR 1410
P ++ ++ G A+ +++S H TT A T L+P +
Sbjct: 1399 QP--------PEEPNGIILG-YQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAY- 1448
Query: 1411 VLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALG 1470
+ S+ + + P + + +T+ P P L+
Sbjct: 1449 IFRLSAKTRQGWGE------------PLEATVITTEKRER-------PAPPRELLVPQAE 1489
Query: 1471 PT--SLRVSWQEPRCE--RPLQGYSVEYQLLNGGE--LHRLNIPNPAQTSVVVEDLLPNH 1524
T SLR+ W P + P++ ++++ + L GE + +I + A T+ VV+ L P
Sbjct: 1490 VTARSLRLQW-VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEA-TACVVDRLRPFT 1547
Query: 1525 SYVFRVRAQSQEG---WGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTA 1581
SY R++A + G + E E V T++ +PG PG + T
Sbjct: 1548 SYKLRLKATNDIGDSDFSSETEAVTTLQD----------VPG--------EPPGSVSATP 1589
Query: 1582 LSPDSLQLSWERPRRP--NGDIVGYLV 1606
+ S+ + W+ PR NG + GY +
Sbjct: 1590 HTTSSVLIQWQPPRDESLNGLLQGYRI 1616
Score = 70.1 bits (170), Expect = 2e-11
Identities = 123/555 (22%), Positives = 206/555 (37%), Gaps = 79/555 (14%)
Query: 1147 WLPP---SGKPMGYRVKYWIQGDSESEAHLLD--SKVPSVELTNLYPYCDYEMKVCAYGA 1201
W PP +G +GY++ Y + S ++ + V T+L P Y ++ A
Sbjct: 1398 WQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTR 1457
Query: 1202 QGEG-PYSSLVSCRTHQEVPSEPGRLAFNVVSSTVT--QLSWAEPAETNGEITAYEVCYG 1258
QG G P + V +E P+ P L T +L W G A + Y
Sbjct: 1458 QGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVP-----GSDGASPIRYF 1512
Query: 1259 LVNDDNRPIGPMKKVLVD-NPKNRMLLIENLRESQPYRYTVKARNGAG---WGPEREAII 1314
+ P G + + + +++ LR Y+ +KA N G + E EA+
Sbjct: 1513 TMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVT 1572
Query: 1315 NLATQPKRP-----------MSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRP 1363
L P P S+ I P ++ +G + Y + + SG++
Sbjct: 1573 TLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAK 1632
Query: 1364 SVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYN 1423
++ + +F +S +TS THL + + V+ T+ YN
Sbjct: 1633 TLKNPIALHAELTAQSSFKTVNSS-----STSTMCELTHLKKYRRYEVIMTA------YN 1681
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRC 1483
+ S P V A P + + L + L V+W P
Sbjct: 1682 IIGES--------PASAPVEVFVGE------AAPAMAPQNVQVTPLTASQLEVTWDPPPP 1727
Query: 1484 ERP---LQGYSVEY-QLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWG 1539
E +QGY + Y + + E ++ + + V +++L + Y+ + A + G G
Sbjct: 1728 ESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDG 1787
Query: 1540 REREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNG 1599
+ + P G + P AP L F+ ++ +L +SW P NG
Sbjct: 1788 PKSD----------------PQQGRTHQ-AAPGAPSFLAFSEITSTTLNVSWGEPAAANG 1830
Query: 1600 DIVGYLVTCE---MAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGP 1656
+ GY V E QG V G+ + L V L++ V Y F+VQART +GP
Sbjct: 1831 ILQGYRVVYEPLAPVQGVSKVVTVEVRGNW-QRWLKVRDLTKGVTYFFRVQARTIT-YGP 1888
Query: 1657 EREGIITIESQDGGP 1671
E + IT +G P
Sbjct: 1889 ELQANITAGPAEGSP 1903
Score = 69.3 bits (168), Expect = 3e-11
Identities = 131/570 (22%), Positives = 206/570 (36%), Gaps = 88/570 (15%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSK----VPS 1180
PQN +A S I F W PP +G GY++ W E+ + + V
Sbjct: 873 PQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHH 932
Query: 1181 VELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
+TNL + Y V + G+GP S+ T ++ P G L+F + T ++SW
Sbjct: 933 GHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSW 992
Query: 1241 AEPAETNGEITAYEVCYGLV-NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVK 1299
EP E NG IT Y++ + + +D+R + N I+ L Y V
Sbjct: 993 QEPLEKNGIITGYQISWEVYGRNDSRLTHTL------NSTTHEYKIQGLSSLTTYTIDVA 1046
Query: 1300 ARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSG 1359
A G G L T +P PD+P S L+ S+ RS +
Sbjct: 1047 AVTAVGTG--------LVTSSTISSGVP--PDLP--------GAPSNLVISNISPRSATL 1088
Query: 1360 SQRPSVSDDT---EHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSS 1416
RP T +V G++ G+ T + + P +
Sbjct: 1089 QFRPGYDGKTSISRWIVEGQV-----GAIGDEEEWVT-------LYEEENEPDAQMLEIP 1136
Query: 1417 TLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPD-TPTRLVFSALGPTSLR 1475
LT Y + P YS SS + PD PT + TSLR
Sbjct: 1137 NLT-PYTHYRFRMKQVNIVGPSPYSP----SSRVIQTLQAPPDVAPTSVTVRTASETSLR 1191
Query: 1476 VSWQE-PRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV---------VEDLLPNHS 1525
+ W P + SV Y++ + R ++ + A VV +E+L
Sbjct: 1192 LRWVPLPDSQYNGNPESVGYRI----KYWRSDLQSSAVAQVVSDRLEREFTIEELEEWME 1247
Query: 1526 YVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPD 1585
Y +++A + G G E + + P +AP + A+S
Sbjct: 1248 YELQMQAFNAVGAGPWSE---VVRGRTRESVP-------------SAAPENVSAEAVSST 1291
Query: 1586 SLQLSWER--PRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1643
+ L+W + NG I+GY + + V G+ +S L + GL + V Y+
Sbjct: 1292 QILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSAL-LAGLRKFVLYE 1350
Query: 1644 FKVQARTTEGFGPEREGIITIESQDGGPFP 1673
+V A T G G +I ++D P P
Sbjct: 1351 LQVLAFTRIGNGVPSTPLILERTKDDAPGP 1380
Score = 59.3 bits (142), Expect = 3e-08
Identities = 129/569 (22%), Positives = 213/569 (37%), Gaps = 83/569 (14%)
Query: 1113 TSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQG-- 1165
TS+++ + PP P+N A ++ I W PP +G GY ++Y + G
Sbjct: 758 TSRLMLPEEPPSAP---PKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLP 814
Query: 1166 DSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR 1225
+ ++ +V +T+L + YE++V AY G G +S V+ T Q VP+ P +
Sbjct: 815 GEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQ 874
Query: 1226 -LAFNVVSSTVTQLSWAEPAE--TNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRM 1282
+ V+ST Q W P + NG Y++ D + + D
Sbjct: 875 NVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPA--DAPEAVTVVTIAPDFHGVHH 932
Query: 1283 LLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGED 1342
I NL++ Y +V G GP + + TQ +P ++ + I+D
Sbjct: 933 GHITNLKKFTAYFTSVLCFTTPGDGPPSTPQL-VWTQEDKPGAVGHLSFTEILDTSLKVS 991
Query: 1343 YDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTH 1402
+ L + + +G Q V GR D + NS TT G
Sbjct: 992 WQEPLEKNGII----TGYQ-------ISWEVYGRNDSRLTHTLNS----TTHEYKIQG-- 1034
Query: 1403 LSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT 1462
LS+ +T T D ++T + L + S+ S + +P P+
Sbjct: 1035 ---------LSSLTTYTIDVAAVTAVG-----------TGLVTSSTISSGVPPDLPGAPS 1074
Query: 1463 RLVFSALGPTSLRVSWQEP-RCERPLQGYSVEYQL-LNGGELHRLNI----PNPAQTSVV 1516
LV S + P S + ++ + + + VE Q+ G E + + P +
Sbjct: 1075 NLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLE 1134
Query: 1517 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPS--AP 1574
+ +L P Y FR++ + G SP P TL P AP
Sbjct: 1135 IPNLTPYTHYRFRMKQVNIVG-----------------PSPYSPSSRVIQTLQAPPDVAP 1177
Query: 1575 GPLVFTALSPDSLQLSW----ERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESR 1630
+ S SL+L W + N + VGY + + A A +V D E
Sbjct: 1178 TSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVA-QVVSDRLERE 1236
Query: 1631 LTVPGLSENVPYKFKVQARTTEGFGPERE 1659
T+ L E + Y+ ++QA G GP E
Sbjct: 1237 FTIEELEEWMEYELQMQAFNAVGAGPWSE 1265
Score = 55.8 bits (133), Expect = 4e-07
Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 24/227 (10%)
Query: 1452 RLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP-LQGYSVEYQLL----NGGELHRLN 1506
R P P+ L FS + T+L VSW EP LQGY V Y+ L ++ +
Sbjct: 1796 RTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVE 1855
Query: 1507 IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF 1566
+ Q + V DL +Y FRV+A++ IT ++ P GS
Sbjct: 1856 VRGNWQRWLKVRDLTKGVTYFFRVQART-----------ITYGPELQANITAGPAEGS-- 1902
Query: 1567 TLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMA-QGGGPATAFRVDGD 1625
P +P ++ T S L L W + GY++ + +G +
Sbjct: 1903 ----PGSPRDVLVTK-SASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRS 1957
Query: 1626 SPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPF 1672
+ L++ L + V Y+F+V A G+G + +Q PF
Sbjct: 1958 ATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 2004
Score = 45.8 bits (107), Expect = 4e-04
Identities = 104/470 (22%), Positives = 171/470 (36%), Gaps = 78/470 (16%)
Query: 1218 EVPSEPGRLAF--NVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLV 1275
E+P P L N S LSW P + N I Y V ++++N P KV +
Sbjct: 666 ELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIV---ELSENNSPW----KVHL 718
Query: 1276 DN--PKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIP 1333
N P+ + + L ++ Y++ V A N G G + A + P+ P S P P
Sbjct: 719 SNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRG-QYSAETSRLMLPEEPPSAP-----P 772
Query: 1334 IVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTT 1393
SG S ++ Q P ++ L + + G +
Sbjct: 773 KNIVASGRTNQSIMVQW----------QPPPETEHNGVLRGYILRYRLAGLPGEYQQRNI 822
Query: 1394 TSAAAYGTHLSPHVPHRVLSTSSTLTR------DYNSLTRSEHSHSTTLPRDYSTLTSVS 1447
TS P V + +++ T+ YN S + T +Y+
Sbjct: 823 TS---------PEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVT---EYTL----- 865
Query: 1448 SHDSRLTAGVPDTPTRLVFS-ALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLN 1506
GVP P + V + A+ T+++ W P ++ + G + Y+LL
Sbjct: 866 -------QGVPTAPPQNVQTEAVNSTTIQFLWNPPP-QQFINGINQGYKLLAW------- 910
Query: 1507 IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF 1566
P A +V V + P+ V + + + V+ + P P +
Sbjct: 911 -PADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTT---PGDGPPSTPQLVW 966
Query: 1567 TLST-PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGD 1625
T P A G L FT + SL++SW+ P NG I GY ++ E+ ++
Sbjct: 967 TQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNST 1026
Query: 1626 SPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL 1675
+ E + + GLS Y V A T G G++T + G P L
Sbjct: 1027 THEYK--IQGLSSLTTYTIDVAAVTAVG-----TGLVTSSTISSGVPPDL 1069
Score = 45.4 bits (106), Expect = 5e-04
Identities = 60/233 (25%), Positives = 86/233 (36%), Gaps = 27/233 (11%)
Query: 1113 TSQMLSSQPPPHGDL-GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQ------- 1164
TS +SS PP DL GAP N R + P G + WI
Sbjct: 1057 TSSTISSGVPP--DLPGAPSNLVISNISPRSATLQFRP--GYDGKTSISRWIVEGQVGAI 1112
Query: 1165 GDSESEAHLLDSK----VPSVELTNLYPYCDYEMKVCAYGAQGEGPYS-SLVSCRTHQEV 1219
GD E L + + +E+ NL PY Y ++ G PYS S +T Q
Sbjct: 1113 GDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAP 1172
Query: 1220 PS-EPGRLAFNVVSSTVTQLSWAEPAET----NGEITAYEVCYGLVNDDNRPIGPMKKVL 1274
P P + S T +L W ++ N E Y + Y + + + +
Sbjct: 1173 PDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQ----V 1228
Query: 1275 VDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
V + R IE L E Y ++A N G GP E ++ T+ P + P
Sbjct: 1229 VSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSE-VVRGRTRESVPSAAP 1280
Score = 31.6 bits (70), Expect = 7.1
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 1568 LSTPSAPGPLVFTALSPDS--LQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGD 1625
+ P +P L+ + S S + LSW RP N I+ Y+V E+++ P +
Sbjct: 665 IELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIV--ELSENNSPWKVHLSNVG 722
Query: 1626 SPESRLTVPGLSENVPYKFKVQARTTEGFG 1655
+ +TV GL+ Y+F+V A G G
Sbjct: 723 PEMTGVTVSGLTPARTYQFRVCAVNEVGRG 752
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 97.1 bits (240), Expect = 1e-19
Identities = 72/209 (34%), Positives = 87/209 (41%), Gaps = 54/209 (25%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C G V G+CVC G++G+ C+ T C R+ C GRG C+ G C+C
Sbjct: 346 CGEGGRCVDGRCVCWPGYTGEDCSTRT--------CPRD-----CRGRGRCEDGECIC-- 390
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCD---CP-------- 576
+ Y G C + CP CN RGRC G+CVC PG+TG C CP
Sbjct: 391 DTGYSGDDCGVRS--CPGD----CNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGR 444
Query: 577 LSNATCIDSNG------------GICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPG 624
N C+ + G G C GRG CE GRC C YT C + PG
Sbjct: 445 CENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPG--YTGRDCG---TRACPG 499
Query: 625 LCEDLRSCVQ----CQAWGTGEKKG-RTC 648
C CV C TGE G R C
Sbjct: 500 DCRGRGRCVDGRCVCNPGFTGEDCGSRRC 528
Score = 89.4 bits (220), Expect = 3e-17
Identities = 69/200 (34%), Positives = 89/200 (44%), Gaps = 44/200 (22%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C+ G V G+CVC G++G +C + C + C GRG C G CVC
Sbjct: 191 CNDQGRCVRGRCVCFPGYTGPSCGWPS--------CPGD-----CQGRGRCVQGVCVC-- 235
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584
+ G C + CPR C+ RGRC G+CVC+PG+TG C CP
Sbjct: 236 RAGFSGPDCSQRS--CPRG----CSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG------ 283
Query: 585 SNGGICNGRGHCECGRCHCHQQSLYTDTICEIN---YSAIHPGLCEDLRSCVQCQAWGTG 641
C+ RG CE GRC C+ YT C + G C+D R CV C TG
Sbjct: 284 -----CSQRGRCENGRCVCNPG--YTGEDCGVRSCPRGCSQRGRCKDGR-CV-CDPGYTG 334
Query: 642 EKKG-RTCE-ECNFKVKMVD 659
E G R+C +C + VD
Sbjct: 335 EDCGTRSCPWDCGEGGRCVD 354
Score = 89.4 bits (220), Expect = 3e-17
Identities = 56/164 (34%), Positives = 75/164 (45%), Gaps = 31/164 (18%)
Query: 443 GLKMDAGIICDVCTCELQKEVRSAR--CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDI 500
GL D +CD RS C G + G+CVC +G+SG+ C +
Sbjct: 536 GLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCG--------V 587
Query: 501 QPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG 560
+ C + CS G CQ G C+C+ EG Y + C CP C+ RGRC G
Sbjct: 588 RQCPND-----CSQHGVCQDGVCICW-EG-YVSEDCSIRT--CPSN----CHGRGRCEEG 634
Query: 561 QCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCH 604
+C+C+PG+TGP+C + A C GRG C G C CH
Sbjct: 635 RCLCDPGYTGPTCATRMCPAD--------CRGRGRCVQGVCLCH 670
Score = 87.4 bits (215), Expect = 1e-16
Identities = 70/200 (35%), Positives = 87/200 (43%), Gaps = 35/200 (17%)
Query: 460 QKEVRSARCSFNGDFVCGQCVCS--EGWSGQTCNCST-GSLSDIQPCLREGE-DKPCSGR 515
Q +VR+ CS +G F +C CS GW G TC+ T + P G C+ +
Sbjct: 136 QTDVRTL-CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQ 194
Query: 516 GECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC-- 573
G C G CVC+ Y G C + + CP C RGRC G CVC G++GP C
Sbjct: 195 GRCVRGRCVCF--PGYTGPSCGWPS--CPGD----CQGRGRCVQGVCVCRAGFSGPDCSQ 246
Query: 574 -DCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEIN---YSAIHPGLCEDL 629
CP C+ RG CE GRC C YT C + G CE+
Sbjct: 247 RSCPRG-----------CSQRGRCEGGRCVCDPG--YTGDDCGMRSCPRGCSQRGRCENG 293
Query: 630 RSCVQCQAWGTGEKKG-RTC 648
R CV C TGE G R+C
Sbjct: 294 R-CV-CNPGYTGEDCGVRSC 311
Score = 71.2 bits (173), Expect = 8e-12
Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 35/184 (19%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C G G+C+C G++G+ C + C + C GRG C G CVC
Sbjct: 470 CRGRGRCESGRCMCWPGYTGRDCGT--------RACPGD-----CRGRGRCVDGRCVC-- 514
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
+ G+ C + +CP C G C G CVC+ G++G C S +C
Sbjct: 515 NPGFTGEDC--GSRRCPGD----CRGHGLCEDGVCVCDAGYSGEDC----STRSC----P 560
Query: 588 GICNGRGHCECGRCHCHQQSLYTDTICEINY---SAIHPGLCEDLRSCVQCQAWGTGEKK 644
G C GRG C GRC C + Y+ C + G+C+D C+ + + + +
Sbjct: 561 GGCRGRGQCLDGRCVC--EDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVSEDCS 617
Query: 645 GRTC 648
RTC
Sbjct: 618 IRTC 621
Score = 70.9 bits (172), Expect = 1e-11
Identities = 47/152 (30%), Positives = 61/152 (40%), Gaps = 31/152 (20%)
Query: 452 CDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKP 511
C + TC + C G G+C+C G++G TC + C +
Sbjct: 616 CSIRTCP-------SNCHGRGRCEEGRCLCDPGYTGPTCAT--------RMCPAD----- 655
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C GRG C G C+C+ Y G+ C + G C R C GQCVC G+ GP
Sbjct: 656 CRGRGRCVQGVCLCHVG--YGGEDCGQEEPPASACPGG-CGPRELCRAGQCVCVEGFRGP 712
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603
C I + G C GRG C G C C
Sbjct: 713 DC--------AIQTCPGDCRGRGECHDGSCVC 736
Score = 67.8 bits (164), Expect = 9e-11
Identities = 140/641 (21%), Positives = 217/641 (33%), Gaps = 123/641 (19%)
Query: 1088 FGAHLGQ---PHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIH 1144
+G H GQ P S + DE + + ++ +PP LG A +
Sbjct: 3019 YGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLG---ELTVTDATPDSLS 3075
Query: 1145 FNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY-GAQG 1203
+W+ P G+ + V+Y GD + +A + V ++ L P Y+M + + G Q
Sbjct: 3076 LSWMVPEGQFDHFLVQYR-NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 3134
Query: 1204 EGPYSSLVSCRTHQEVPSEP-------------GRLAFNVVSSTVTQLSWAEP------- 1243
GP S++ P+EP G L S LSW P
Sbjct: 3135 VGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSF 3194
Query: 1244 -------------AETNGEITAYEV------------CYGLVNDDNRPIGPMKKVLVDNP 1278
GE + V YGL + + +GP+ V + P
Sbjct: 3195 TVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGL--HEGQRVGPVSTVGITAP 3252
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGW----GPEREAIINLATQPKRPMSIPIIPDIPI 1334
L +E G W GP ++ +P ++P+ D+
Sbjct: 3253 LPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRA 3312
Query: 1335 VDAQSGED----YDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHR 1390
V A SG D Y L + R + DT+ + L
Sbjct: 3313 V-AVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTK-------------PSPRLGE 3358
Query: 1391 MTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTR----SEHSHSTTLP-----RDYS 1441
+T T A LS VP + +D + + + + T+ R Y
Sbjct: 3359 LTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYR 3418
Query: 1442 TLTSVSSHDSRLTAGVPDTPTRLVFSALGP------------TSLRVSWQEPRCERPLQG 1489
L S RL D+ T + L P +SLR+SW + P
Sbjct: 3419 FLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV--AQGPFDS 3476
Query: 1490 YSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI 1548
+ V+Y+ +G +P A Q +V VEDL P Y F + G +R G ++
Sbjct: 3477 FVVQYRDTDG---QPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLL----GGKRLGPVSA 3529
Query: 1549 ESQVHPQSPLCPLPGSAFTLSTPSAP-----GPLVFTALSPDSLQLSWERPRRPNGDIVG 1603
P+ P P P G L T +PDS++LSW + P V
Sbjct: 3530 LGMTAPEEDT---PAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFV- 3585
Query: 1604 YLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKF 1644
+ G A VDGD +S++ + GL + PY+F
Sbjct: 3586 ----VQYEDTNGQPQALLVDGD--QSKILISGLEPSTPYRF 3620
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 32/116 (27%)
Query: 466 ARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKP--------CSGRGE 517
A C G V G C+C G+ G+ C G+++P C R
Sbjct: 654 ADCRGRGRCVQGVCLCHVGYGGEDC----------------GQEEPPASACPGGCGPREL 697
Query: 518 CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC 573
C+ G CVC EG + G C CP C RG C G CVC+ G+ G C
Sbjct: 698 CRAGQCVCV-EG-FRGPDCAIQT--CPGD----CRGRGECHDGSCVCKDGYAGEDC 745
Score = 53.1 bits (126), Expect = 2e-06
Identities = 136/605 (22%), Positives = 219/605 (36%), Gaps = 118/605 (19%)
Query: 1088 FGAHLGQ---PHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNP-----NAKAAG 1139
+G H G+ P ST + +++D + + ++ P G P+ P +
Sbjct: 2480 YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAP-----GPPEEPLLGELTVTGSS 2534
Query: 1140 SRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCA- 1198
+ +W P G+ + V+Y + D +A + + V + L P Y+M +
Sbjct: 2535 PDSLSLSWTVPQGRFDSFTVQYKDR-DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGL 2593
Query: 1199 YGAQGEGPYSSLV----SCRTHQEVPS---EP------GRLAFNVVSSTVTQLSWAEPAE 1245
+ + GP S++ T Q VP+ EP G L + LSW P
Sbjct: 2594 HEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVP-- 2651
Query: 1246 TNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA-RNGA 1304
G+ + V Y N D +P K V V ++ + I L Y+ + G
Sbjct: 2652 -EGQFDHFLVQYR--NGDGQP----KAVRVPGHEDGVT-ISGLEPDHKYKMNLYGFHGGQ 2703
Query: 1305 GWGP-----------EREAIINLATQPKRPMSIPIIPDIPIVDAQSGE----------DY 1343
GP E + L+T+ P P++ ++ + + +
Sbjct: 2704 RVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHF 2763
Query: 1344 DSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHL 1403
DSF + D P Q V + + G ++ PG +H YG H
Sbjct: 2764 DSFTVQYKDRDGRP---QVMRVRGEESEVTVGGLE---PGRKYKMH--------LYGLHE 2809
Query: 1404 SPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTR 1463
R + ST+ +T E + +P T T + RL
Sbjct: 2810 G-----RRVGPVSTV-----GVTEDEAETTQAVP----TTTPEPPNKPRLG--------E 2847
Query: 1464 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLP 1522
L + P SL +SW P E + V+Y+ NG G+ + +P + V + L P
Sbjct: 2848 LTVTDATPDSLSLSWMVP--EGQFDHFLVQYR--NGDGQPKVVRVPGH-EDGVTISGLEP 2902
Query: 1523 NHSYVFRVRAQSQEGWGREREGVITI--ESQVHPQSPLCPLPGSAFTLSTPSAP--GPLV 1578
+H Y + G +R G I++ + ++P P S P P G L
Sbjct: 2903 DHKYKMNLYGFH----GGQRVGPISVIGVTAAEEETP-APTEPSTEAPEPPEEPLLGELT 2957
Query: 1579 FTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSE 1638
T SPDSL LSW P+ G + T + G RV G+ ES +TV GL
Sbjct: 2958 VTGSSPDSLSLSWTIPQ---GRFDSF--TVQYKDRDGRPQVVRVRGE--ESEVTVGGLEP 3010
Query: 1639 NVPYK 1643
YK
Sbjct: 3011 GCKYK 3015
Score = 50.4 bits (119), Expect = 1e-05
Identities = 118/517 (22%), Positives = 180/517 (34%), Gaps = 117/517 (22%)
Query: 1113 TSQMLSSQPPPH-GDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEA 1171
T+ L + PPH G+L + S + +W G + V+Y D + A
Sbjct: 3438 TTAPLEKELPPHLGELTVAEET------SSSLRLSWTVAQGPFDSFVVQYR-DTDGQPRA 3490
Query: 1172 HLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGE---GPYSSLVSCRTHQEVPS------- 1221
+ + +V + +L P Y K YG G GP S+L ++ P+
Sbjct: 3491 VPVAADQRTVTVEDLEPGKKY--KFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEA 3548
Query: 1222 ----EPGRLAFNVVSSTVT---QLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVL 1274
E RL V+ T +LSW+ G ++ V Y N G + +L
Sbjct: 3549 PEPPEEPRLGVLTVTDTTPDSMRLSWSV---AQGPFDSFVVQYEDTN------GQPQALL 3599
Query: 1275 VDNPKNRMLLIENLRESQPYRYTVKA-RNGAGWGP-EREAIINLATQPKRPM-SIPIIPD 1331
VD +++ +LI L S PYR+ + G GP E LA + S P +
Sbjct: 3600 VDGDQSK-ILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQ 3658
Query: 1332 IPIVDAQSGE----------DYDSFLMYSDDVLRSPSGSQ-RPSVSDDTEHLVNGRMDFA 1380
+ + D + +DSFL+ + SPS + P E +V G A
Sbjct: 3659 LSVTDVTTSSLRLNWEAPPGAFDSFLLRFG--VPSPSTLEPHPRPLLQRELMVPGTRHSA 3716
Query: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
L T S YG PH + T+ TL+
Sbjct: 3717 V---LRDLRSGTLYSLTLYGLR-GPHKADSIQGTARTLSP-------------------- 3752
Query: 1441 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1500
V ++P L FS + TS +V+W P + V YQL +GG
Sbjct: 3753 ----------------VLESPRDLQFSEIRETSAKVNWMPPPSRA--DSFKVSYQLADGG 3794
Query: 1501 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1560
E + + A+T ++ L+P Y V S G+ P
Sbjct: 3795 EPQSVQVDGQARTQ-KLQGLIPGARY--EVTVVSVRGFEESE-----------------P 3834
Query: 1561 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRP 1597
L G F + P P L L+ L W+ P+ P
Sbjct: 3835 LTG--FLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 3869
Score = 50.1 bits (118), Expect = 2e-05
Identities = 136/619 (21%), Positives = 220/619 (35%), Gaps = 100/619 (16%)
Query: 1065 QEVDSLLRGRQV-RRFHVQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPP 1123
QE +RG + R++ + L G LG P S + D E ++ + ++ +PP
Sbjct: 2571 QESKVTVRGLEPGRKYKMHLYGLHEGRRLG-PVSAVGVTEDEAETTQAVPT--MTPEPPI 2627
Query: 1124 HGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVEL 1183
LG +A + +W P G+ + V+Y GD + +A + V +
Sbjct: 2628 KPRLGELTMTDATPDS---LSLSWTVPEGQFDHFLVQYR-NGDGQPKAVRVPGHEDGVTI 2683
Query: 1184 TNLYPYCDYEMKVCAY-GAQGEGPYSSLVSCRTHQEVPS-------------EP--GRLA 1227
+ L P Y+M + + G Q GP S + +E PS EP G L
Sbjct: 2684 SGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELT 2743
Query: 1228 FNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIEN 1287
S LSW P G ++ V Y + D RP +V+ + + +
Sbjct: 2744 VTGSSPDSLSLSWTIP---QGHFDSFTVQYK--DRDGRP-----QVMRVRGEESEVTVGG 2793
Query: 1288 LRESQPYR-YTVKARNGAGWGP---------EREAIINLATQPKRPMSIPIIPDIPIVDA 1337
L + Y+ + G GP E E + T P + P + ++ + DA
Sbjct: 2794 LEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDA 2853
Query: 1338 QSGEDYDSFLM----YSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTT 1393
S+++ + +++ +G +P V V G D H+
Sbjct: 2854 TPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVR-----VPGHEDGVTISGLEPDHKYKM 2908
Query: 1394 TSAAAYGTHLSPHV-PHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSR 1452
YG H V P V+ ++ T P + ST +
Sbjct: 2909 N---LYGFHGGQRVGPISVIGVTAA-------------EEETPAPTEPSTEAPEPPEEPL 2952
Query: 1453 LTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQ 1512
L L + P SL +SW P+ ++V+Y+ +G ++ +
Sbjct: 2953 LG--------ELTVTGSSPDSLSLSWTIPQGR--FDSFTVQYKDRDGRP--QVVRVRGEE 3000
Query: 1513 TSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPS 1572
+ V V L P Y + EG +R G ++ P+ A TP
Sbjct: 3001 SEVTVGGLEPGCKYKMHLYGL-HEG---QRVGPVSAVGVTAPKDEAETT--QAVPTMTPE 3054
Query: 1573 AP-----GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1627
P G L T +PDSL LSW P G +LV + G G A RV G
Sbjct: 3055 PPIKPRLGELTVTDATPDSLSLSW---MVPEGQFDHFLV--QYRNGDGQPKAVRVPGH-- 3107
Query: 1628 ESRLTVPGLSENVPYKFKV 1646
E +T+ GL + YK +
Sbjct: 3108 EDGVTISGLEPDHKYKMNL 3126
Score = 48.5 bits (114), Expect = 6e-05
Identities = 64/240 (26%), Positives = 93/240 (38%), Gaps = 30/240 (12%)
Query: 1464 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLP 1522
L + + P SLR+SW + P + V+Y+ G +P + V V L P
Sbjct: 1267 LTVTGVTPDSLRLSWTV--AQGPFDSFMVQYKDAQG---QPQAVPVAGDENEVTVPGLDP 1321
Query: 1523 NHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPG-SAFTLSTPSAP-----GP 1576
+ Y + GR+R G ++ ++ PQ + P + P +P G
Sbjct: 1322 DRKYKMNLYGLR----GRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGE 1377
Query: 1577 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1636
L T SPDSL L W P+ G + T + G A RV G ES +TV GL
Sbjct: 1378 LTVTGSSPDSLSLFWTVPQ---GSFDSF--TVQYKDRDGRPRAVRVGG--KESEVTVGGL 1430
Query: 1637 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTT 1696
YK + EG +R G + S G PQ + PL+ +T T
Sbjct: 1431 EPGHKYKMHLYG-LHEG---QRVGPV---SAVGVTAPQQEETPPATESPLEPRLGELTVT 1483
Score = 47.4 bits (111), Expect = 1e-04
Identities = 145/676 (21%), Positives = 226/676 (33%), Gaps = 165/676 (24%)
Query: 1024 VSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQL 1083
V Y+ +DG Q +PVEG L +E+ V L+ R+ + L
Sbjct: 1808 VQYKDRDGQPQ----VVPVEGSL--------REVSVPGLD-----------PAHRYKLLL 1844
Query: 1084 SNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKI 1143
G +G P S I +E + T+ + P G+L + A S +
Sbjct: 1845 YGLHHGKRVG-PISAVAITAGREETETETTAPTPPAPEPHLGEL------TVEEATSHTL 1897
Query: 1144 HFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG--- 1200
H +W+ G+ + ++Y D + + + + L+ L D+ V YG
Sbjct: 1898 HLSWMVTEGEFDSFEIQY-TDRDGQLQMVRIGGDRNDITLSGLES--DHRYLVTLYGFSD 1954
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEP-------------GRLAFNVVSSTVTQLSWAEPAETN 1247
+ GP +E PSEP G L + LSW P
Sbjct: 1955 GKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVP---E 2011
Query: 1248 GEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA-RNGAGW 1306
G+ + V Y N D +P K V V + + I L Y+ + G
Sbjct: 2012 GQFDHFLVQYR--NGDGQP----KAVRVPGHEEGVT-ISGLEPDHKYKMNLYGFHGGQRM 2064
Query: 1307 GPEREAIINLA-------TQPK----RPMSIPIIPDIPIVDAQSGE----------DYDS 1345
GP + A T+P P P++ ++ + + +DS
Sbjct: 2065 GPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 2124
Query: 1346 FLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSP 1405
F + D P Q V + + G ++ PG +H YG H
Sbjct: 2125 FTVQYKDRDGRP---QVVRVGGEESEVTVGGLE---PGRKYKMH--------LYGLHEG- 2169
Query: 1406 HVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT--- 1462
RV S+ T P + S PD P
Sbjct: 2170 ---RRVGPVSAV---------------GVTAPEEES----------------PDAPLAKL 2195
Query: 1463 ---RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVE 1518
++ + SL +SW P E + V+++ NG G+ + +P + V +
Sbjct: 2196 RLGQMTVRDITSDSLSLSWTVP--EGQFDHFLVQFK--NGDGQPKAVRVPGH-EDGVTIS 2250
Query: 1519 DLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP-- 1576
L P+H Y + G +R G ++ P P S + P P P
Sbjct: 2251 GLEPDHKYKMNLYGFH----GGQRVGPVSAVGLTAPGKDEEMAPAS----TEPPTPEPPI 2302
Query: 1577 ------LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESR 1630
L T +PDSL LSW P G +LV + G G A RV G E R
Sbjct: 2303 KPRLEELTVTDATPDSLSLSW---TVPEGQFDHFLV--QYKNGDGQPKATRVPGH--EDR 2355
Query: 1631 LTVPGLSENVPYKFKV 1646
+T+ GL + YK +
Sbjct: 2356 VTISGLEPDNKYKMNL 2371
Score = 45.4 bits (106), Expect = 5e-04
Identities = 63/241 (26%), Positives = 98/241 (40%), Gaps = 38/241 (15%)
Query: 1473 SLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRA 1532
SL + W P E + ++Y+ +G + + + P Q S V+ L P Y F +
Sbjct: 1077 SLLLRWTVPEGE--FDSFVIQYKDRDG-QPQVVPVEGP-QRSAVITSLDPGRKYKFVLYG 1132
Query: 1533 QSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWE 1592
G++R G + E+++ PQS P PG TP G L T +PDSL LSW
Sbjct: 1133 FV----GKKRHGPLVAEAKILPQSD--PSPG------TPPHLGNLWVTDPTPDSLHLSW- 1179
Query: 1593 RPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKV-QARTT 1651
P G ++V + G V+G PE V L + Y+F +
Sbjct: 1180 --TVPEGQFDTFMV--QYRDRDGRPQVVPVEG--PERSFVVSSLDPDHKYRFTLFGIANK 1233
Query: 1652 EGFGP-EREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYS-------SITTTHTSATEP 1703
+ +GP +G E ++ P P+ + PL E + S+ + T A P
Sbjct: 1234 KRYGPLTADGTTAPERKEEPPRPE------FLEQPLLGELTVTGVTPDSLRLSWTVAQGP 1287
Query: 1704 F 1704
F
Sbjct: 1288 F 1288
Score = 43.1 bits (100), Expect = 0.002
Identities = 55/196 (28%), Positives = 78/196 (39%), Gaps = 27/196 (13%)
Query: 1458 PDTPT--RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1515
P+ P L + P SL +SW P+ ++V+Y+ +G ++ ++ V
Sbjct: 2409 PEEPLLGELTVTGSSPDSLSLSWTVPQGR--FDSFTVQYKDRDGRP--QVVRVGGEESEV 2464
Query: 1516 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1575
V L P Y + + GR R G ++ PQ + P T APG
Sbjct: 2465 TVGGLEPGRKYKMHLYGLHE---GR-RVGPVSTVGVTAPQEDVDETPSP--TEPGTEAPG 2518
Query: 1576 P--------LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1627
P L T SPDSL LSW P+ G + T + G A RV G
Sbjct: 2519 PPEEPLLGELTVTGSSPDSLSLSWTVPQ---GRFDSF--TVQYKDRDGRPQAVRVGGQ-- 2571
Query: 1628 ESRLTVPGLSENVPYK 1643
ES++TV GL YK
Sbjct: 2572 ESKVTVRGLEPGRKYK 2587
Score = 40.8 bits (94), Expect = 0.012
Identities = 60/250 (24%), Positives = 95/250 (38%), Gaps = 44/250 (17%)
Query: 1340 GEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNG---RMDFA-FPGSTNS--LHRMTT 1393
GE +D + D G + P++ HL+ R ++ PG ++ + + T
Sbjct: 727 GECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPT 786
Query: 1394 TSAAAYGTHLSPHVPHRVLSTSSTLTR-------DYNSLTRSEHSHSTTLPRDYSTLTSV 1446
T A SP RV S++S + +Y R+ S LP + T +
Sbjct: 787 TEGA------SPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMI 840
Query: 1447 SSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLN 1506
D P L A+ PT+L + W P+ E + + V Y + G + RL
Sbjct: 841 ------------DGPQDLRVVAVTPTTLELGWLRPQAE--VDRFVVSY-VSAGNQRVRLE 885
Query: 1507 IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF 1566
+P P ++ DL+P YV V A ER ++ + V + PL G
Sbjct: 886 VP-PEADGTLLTDLMPGVEYVVTVTA--------ERGRAVSYPASVRANTGSSPL-GLLG 935
Query: 1567 TLSTPSAPGP 1576
T P GP
Sbjct: 936 TTDEPPPSGP 945
Score = 40.8 bits (94), Expect = 0.012
Identities = 56/225 (24%), Positives = 89/225 (39%), Gaps = 34/225 (15%)
Query: 1450 DSRLTAGVPDTPT----RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRL 1505
++ TA P P L +L +SW E + ++Y +G +L +
Sbjct: 1869 ETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGE--FDSFEIQYTDRDG-QLQMV 1925
Query: 1506 NIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSA 1565
I + + + L +H Y+ + S + G + +E+ P+ P +A
Sbjct: 1926 RIGGD-RNDITLSGLESDHRYLVTLYGFSDG----KHVGPVHVEALTVPEEEKPSEPPTA 1980
Query: 1566 FTLSTPSAP-----GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF 1620
TP P G L T +PDSL LSW P G +LV + G G A
Sbjct: 1981 ----TPEPPIKPRLGELTVTDATPDSLSLSW---TVPEGQFDHFLV--QYRNGDGQPKAV 2031
Query: 1621 RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGF-GPEREGIITI 1664
RV G E +T+ GL + YK + GF G +R G +++
Sbjct: 2032 RVPGH--EEGVTISGLEPDHKYKMNLY-----GFHGGQRMGPVSV 2069
Score = 40.4 bits (93), Expect = 0.015
Identities = 51/177 (28%), Positives = 71/177 (40%), Gaps = 20/177 (11%)
Query: 1471 PTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1529
P SL +SW P E + V+Y+ NG G+ +P + V + L P++ Y
Sbjct: 2316 PDSLSLSWTVP--EGQFDHFLVQYK--NGDGQPKATRVPGH-EDRVTISGLEPDNKYKMN 2370
Query: 1530 VRAQSQEGWGREREGVIT-IESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDS 1586
+ G +R G ++ I + P S P P G L T SPDS
Sbjct: 2371 LYGFH----GGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDS 2426
Query: 1587 LQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1643
L LSW P+ G + T + G RV G+ ES +TV GL YK
Sbjct: 2427 LSLSWTVPQ---GRFDSF--TVQYKDRDGRPQVVRVGGE--ESEVTVGGLEPGRKYK 2476
Score = 40.0 bits (92), Expect = 0.020
Identities = 117/555 (21%), Positives = 193/555 (34%), Gaps = 97/555 (17%)
Query: 1118 SSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSK 1177
SS PP G+L S + W P G+ + ++Y + D + + ++
Sbjct: 1059 SSGPPRLGELTVTDRT------SDSLLLRWTVPEGEFDSFVIQYKDR-DGQPQVVPVEGP 1111
Query: 1178 VPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVS-------CRTHQEVPSEPGRLAFNV 1230
S +T+L P Y K YG G+ + LV+ P G L
Sbjct: 1112 QRSAVITSLDPGRKY--KFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTD 1169
Query: 1231 VSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRE 1290
+ LSW P G+ + V Y + D RP + V V+ P+ R ++ +L
Sbjct: 1170 PTPDSLHLSWTVP---EGQFDTFMVQYR--DRDGRP----QVVPVEGPE-RSFVVSSLDP 1219
Query: 1291 SQPYRYTVKA-RNGAGWGP---EREAIINLATQPKRP--MSIPIIPDIPIVDAQSGE--- 1341
YR+T+ N +GP + +P RP + P++ ++ +
Sbjct: 1220 DHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRL 1279
Query: 1342 -------DYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTT 1394
+DSF++ D P P D+ E V G + ++M
Sbjct: 1280 SWTVAQGPFDSFMVQYKDAQGQPQAV--PVAGDENEVTVPGL-------DPDRKYKMNL- 1329
Query: 1395 SAAAYGTHLSPHV-PHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRL 1453
YG V P V++ ++ E T P + T S + L
Sbjct: 1330 ----YGLRGRQRVGPESVVAKTAP----------QEDVDETPSPTELGTEAPESPEEPLL 1375
Query: 1454 TAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQT 1513
L + P SL + W P + ++V+Y+ +G R ++
Sbjct: 1376 G--------ELTVTGSSPDSLSLFWTVP--QGSFDSFTVQYKDRDGRP--RAVRVGGKES 1423
Query: 1514 SVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSA 1573
V V L P H Y + EG +R G ++ PQ P P + +P
Sbjct: 1424 EVTVGGLEPGHKYKMHLYGL-HEG---QRVGPVSAVGVTAPQQEETP-PAT----ESPLE 1474
Query: 1574 P--GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRL 1631
P G L T ++P+S+ LSW P G ++V + G D + +
Sbjct: 1475 PRLGELTVTDVTPNSVGLSW---TVPEGQFDSFIVQYKDKDGQPQVVPVAAD----QREV 1527
Query: 1632 TVPGLSENVPYKFKV 1646
TV L YK +
Sbjct: 1528 TVYNLEPERKYKMNM 1542
Score = 38.9 bits (89), Expect = 0.044
Identities = 47/184 (25%), Positives = 76/184 (41%), Gaps = 23/184 (12%)
Query: 1464 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLP 1522
L + + P S+ +SW P E + V+Y+ +G +P A Q V V +L P
Sbjct: 1480 LTVTDVTPNSVGLSWTVP--EGQFDSFIVQYKDKDG---QPQVVPVAADQREVTVYNLEP 1534
Query: 1523 NHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFT 1580
Y + +R G +++ V +PL P P + + P P G L T
Sbjct: 1535 ERKYKMNMYGLHDG----QRMGPLSV---VIVTAPLPPAPATEAS-KPPLEPRLGELTVT 1586
Query: 1581 ALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENV 1640
++PDS+ LSW P G+ ++V + G D + +T+P L +
Sbjct: 1587 DITPDSVGLSW---TVPEGEFDSFVVQYKDRDGQPQVVPVAAD----QREVTIPDLEPSR 1639
Query: 1641 PYKF 1644
YKF
Sbjct: 1640 KYKF 1643
Score = 38.9 bits (89), Expect = 0.044
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 30/203 (14%)
Query: 1464 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLP 1522
L + + P S+ +SW P E + V+Y+ +G +P A Q V + DL P
Sbjct: 1583 LTVTDITPDSVGLSWTVPEGE--FDSFVVQYKDRDG---QPQVVPVAADQREVTIPDLEP 1637
Query: 1523 NHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTAL 1582
+ Y F + Q+G +R +++E++ + P P G L T
Sbjct: 1638 SRKYKFLLFG-IQDG---KRRSPVSVEAKTVARGDASP--------GAPPRLGELWVTDP 1685
Query: 1583 SPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPY 1642
+PDSL+LSW P G ++V + GP V + E +TV L Y
Sbjct: 1686 TPDSLRLSW---TVPEGQFDSFVV--QFKDKDGPQV---VPVEGHERSVTVTPLDAGRKY 1737
Query: 1643 KFKVQARTTEGFGPEREGIITIE 1665
+F + G +R G +T +
Sbjct: 1738 RFLLYGL----LGKKRHGPLTAD 1756
Score = 35.8 bits (81), Expect = 0.38
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 1127 LGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNL 1186
L AP++ AK R W P +P GY + + G E LL + S +L L
Sbjct: 3931 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEI-LLPGGITSHQLLGL 3989
Query: 1187 YPYCDYEMKVCAYGAQ 1202
+P Y ++ A Q
Sbjct: 3990 FPSTSYNARLQAMWGQ 4005
Score = 33.5 bits (75), Expect = 1.9
Identities = 51/230 (22%), Positives = 79/230 (34%), Gaps = 47/230 (20%)
Query: 1469 LGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVE-DLLPNHSYV 1527
L T++R W P+ Y +++ G P+ S + L P Y
Sbjct: 760 LEETTVRTEWTP--APGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ 817
Query: 1528 FRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSL 1587
VRA WG LP S + P L A++P +L
Sbjct: 818 VTVRALRGTSWG---------------------LPASKTITTMIDGPQDLRVVAVTPTTL 856
Query: 1588 QLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLT--VPGL--------- 1636
+L W RP ++ ++V+ G V ++ + LT +PG+
Sbjct: 857 ELGW---LRPQAEVDRFVVS--YVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAE 911
Query: 1637 -SENVPYKFKVQARTTEGFGPEREGII--TIESQDGGPFPQLGSRAGLFQ 1683
V Y V+A T G G++ T E GP G++A L Q
Sbjct: 912 RGRAVSYPASVRANT----GSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQ 957
Score = 33.1 bits (74), Expect = 2.4
Identities = 62/227 (27%), Positives = 92/227 (40%), Gaps = 39/227 (17%)
Query: 1458 PDTPT--RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1515
P+ P L + P SL +SW P+ ++V+Y+ +G ++ ++ V
Sbjct: 3162 PEEPLLGELTVTGSSPDSLSLSWTVPQGR--FDSFTVQYKDRDGQP--QVVRVRGEESEV 3217
Query: 1516 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1575
V L P Y + EG +R G + S V +PL P P L G
Sbjct: 3218 TVGGLEPGRKYKMHLYGL-HEG---QRVGPV---STVGITAPL-PTP-----LPVEPRLG 3264
Query: 1576 PLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPG 1635
L A++ DS+ LSW + G +LV AQ G A V GD + V G
Sbjct: 3265 ELAVAAVTSDSVGLSWTVAQ---GPFDSFLVQYRDAQ--GQPQAVPVSGDL--RAVAVSG 3317
Query: 1636 LSENVPYKFKVQARTTEGFG---PEREGIITIESQ---DGGPFPQLG 1676
L YKF + FG +R G + +E++ D P P+LG
Sbjct: 3318 LDPARKYKFLL-------FGLQNGKRHGPVPVEARTAPDTKPSPRLG 3357
Score = 31.2 bits (69), Expect = 9.3
Identities = 54/241 (22%), Positives = 94/241 (39%), Gaps = 32/241 (13%)
Query: 1464 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPN 1523
L +A+ S+ +SW + P + V+Y+ G + + + + +V V L P
Sbjct: 3266 LAVAAVTSDSVGLSWTV--AQGPFDSFLVQYRDAQG-QPQAVPVSGDLR-AVAVSGLDPA 3321
Query: 1524 HSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALS 1583
Y F + Q G +R G + +E++ P + P G L T +
Sbjct: 3322 RKYKFLLFGL-QNG---KRHGPVPVEARTAPDTKPSPRLGE------------LTVTDAT 3365
Query: 1584 PDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1643
PDS+ LSW P G+ ++V + G + + +TV GL + Y+
Sbjct: 3366 PDSVGLSW---TVPEGEFDSFVVQYKDKDGRLQVVPVAAN----QREVTVQGLEPSRKYR 3418
Query: 1644 FKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEP 1703
F + + G +R G I+ +S +L G + SS+ + T A P
Sbjct: 3419 FLLYGLS----GRKRLGPISADSTTAPLEKELPPHLGELT-VAEETSSSLRLSWTVAQGP 3473
Query: 1704 F 1704
F
Sbjct: 3474 F 3474
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 96.7 bits (239), Expect = 2e-19
Identities = 135/551 (24%), Positives = 217/551 (39%), Gaps = 92/551 (16%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 326 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 385
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 386 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 445
Query: 1248 GEITAYEVCYGLVNDDNRPIGP-MKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
G+I Y V Y + D + + MK + D +++ I NL + Y V A G
Sbjct: 446 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD---SQITTIGNLVPQKTYSVKVLAFTSIGD 500
Query: 1307 GPEREAIINLATQ---PKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRP 1363
GP + I + TQ P +P++ P + ++ ++ S RS + +
Sbjct: 501 GP-LSSDIQVITQTGVPGQPLNFKAEP-----------ESETSILLSWTPPRSDTIANYE 548
Query: 1364 SVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYN 1423
V D EH R+ PG++ L + S Y L+ P + ++++ ++
Sbjct: 549 LVYKDGEHGEEQRITIE-PGTSYRLQGLKPNS--LYYFRLAARSPQGLGASTAEIS---- 601
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRC 1483
R+ S + P+D S TS SS TS+ VSWQ P
Sbjct: 602 --ARTMQSKPSAPPQDIS-CTSPSS-----------------------TSILVSWQPPPV 635
Query: 1484 ERP---LQGYSVEYQLLNGGE---LHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEG 1537
E+ + YS++Y ++G + L IP+ T ++E L Y V A + G
Sbjct: 636 EKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDT-TKYLLEQLEKWTEYRITVTAHTDVG 694
Query: 1538 WGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER--PR 1595
G E V+ ++ P P P + A++ S+++SW P
Sbjct: 695 PGPESLSVLIRTNEDVPSGP----------------PRKVEVEAVNSTSVKVSWRSPVPN 738
Query: 1596 RPNGDIVGYLVTCEMAQGGGP-----------ATAFRVDGDSPESRLTVPGLSENVPYKF 1644
+ +G I GY V + G P A A D+ E + + GL Y
Sbjct: 739 KQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSL 798
Query: 1645 KVQARTTEGFG 1655
V A TT+G G
Sbjct: 799 TVTAYTTKGDG 809
Score = 85.9 bits (211), Expect = 3e-16
Identities = 138/636 (21%), Positives = 229/636 (36%), Gaps = 120/636 (18%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 397 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 456
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 457 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 514
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 567
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQ 1338
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 568 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP----------- 613
Query: 1339 SGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAA 1398
D SPS T LV+ + P + + T +
Sbjct: 614 -----------QDISCTSPS---------STSILVSWQ-----PPPVEKQNGIITEYSIK 648
Query: 1399 Y-GTHLSPHVPHRVLSTSSTLTR----------DYNSLTRSEHSHSTTLPRDYSTLTSVS 1447
Y PH +L S T+ +Y +T + H+ P S L
Sbjct: 649 YTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYR-ITVTAHTDVGPGPESLSVLI--- 704
Query: 1448 SHDSRLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH 1503
R VP P R V A+ TS++VSW+ P + ++GY V Y + GE
Sbjct: 705 ----RTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPK 760
Query: 1504 -------------RLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIES 1550
+ + + +++ L P SY V A + +G G + + +
Sbjct: 761 GQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT 820
Query: 1551 QVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEM 1610
P P LV ++ + W P G + GY +
Sbjct: 821 GAVPGKP------------------RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG- 861
Query: 1611 AQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGG 1670
+ P T ++ E T + + Y F++ AR GFG E I+I +
Sbjct: 862 RKDMEPLTT--LEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPT 919
Query: 1671 PFPQLGSRAGL--------FQHPLQSEYSSITTTHT 1698
FPQ G +Q P+ +E + I T +T
Sbjct: 920 GFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYT 955
Score = 70.9 bits (172), Expect = 1e-11
Identities = 97/432 (22%), Positives = 168/432 (38%), Gaps = 63/432 (14%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYW-IQGDSESEAHLLD--SKVPSV 1181
PQ+ + + S I +W PP +G Y +KY + G+ + +L S
Sbjct: 613 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKY 672
Query: 1182 ELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSW 1240
L L + +Y + V A+ G GP S V RT+++VPS P R + V+ST ++SW
Sbjct: 673 LLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSW 732
Query: 1241 AEPA--ETNGEITAYEVCYGLVNDDNRPIGPMKKVLV--------DNPKNRMLLIENLRE 1290
P + +G+I Y+V Y + + PM K ++ D+ ++I L+
Sbjct: 733 RSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQP 792
Query: 1291 SQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYS 1350
Y TV A G G ++PK + +P P + + + + +
Sbjct: 793 ETSYSLTVTAYTTKGDGAR--------SKPKLVSTTGAVPGKPRLVINHTQMNTALIQWH 844
Query: 1351 DDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHR 1410
V D L R+ F + +TT + H + H+
Sbjct: 845 PPV-------------DTFGPLQGYRLKFG----RKDMEPLTTLEFSEKEDHFTATDIHK 887
Query: 1411 VLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALG 1470
S L+ E ++P + T + H T+
Sbjct: 888 GASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTS--------------- 932
Query: 1471 PTSLRVSWQEP-RCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYV 1527
TS+++SWQ P ER + Y++ Y+ +N L + PA T++ + L P+ +Y
Sbjct: 933 -TSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYD 991
Query: 1528 FRVRAQSQEGWG 1539
+VRA + +G G
Sbjct: 992 VKVRAHTSKGPG 1003
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 914 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 973
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 974 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1033
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1034 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1082
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1083 FVLTNRGNSAGG 1094
Score = 35.0 bits (79), Expect = 0.64
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
Query: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESR 1630
P PG V T + S+ L+W+ N + V Y + + +DG + +R
Sbjct: 323 PKPPGTPVVTESTATSITLTWDSG---NPEPVSYYIIQHKPKNSEELYK-EIDGVAT-TR 377
Query: 1631 LTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQ 1667
+V GLS Y+F+V A G GP E ++T S+
Sbjct: 378 YSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSE 414
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 96.7 bits (239), Expect = 2e-19
Identities = 135/551 (24%), Positives = 217/551 (39%), Gaps = 92/551 (16%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 313 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 372
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 373 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 432
Query: 1248 GEITAYEVCYGLVNDDNRPIGP-MKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
G+I Y V Y + D + + MK + D +++ I NL + Y V A G
Sbjct: 433 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD---SQITTIGNLVPQKTYSVKVLAFTSIGD 487
Query: 1307 GPEREAIINLATQ---PKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRP 1363
GP + I + TQ P +P++ P + ++ ++ S RS + +
Sbjct: 488 GP-LSSDIQVITQTGVPGQPLNFKAEP-----------ESETSILLSWTPPRSDTIANYE 535
Query: 1364 SVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYN 1423
V D EH R+ PG++ L + S Y L+ P + ++++ ++
Sbjct: 536 LVYKDGEHGEEQRITIE-PGTSYRLQGLKPNS--LYYFRLAARSPQGLGASTAEIS---- 588
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRC 1483
R+ S + P+D S TS SS TS+ VSWQ P
Sbjct: 589 --ARTMQSKPSAPPQDIS-CTSPSS-----------------------TSILVSWQPPPV 622
Query: 1484 ERP---LQGYSVEYQLLNGGE---LHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEG 1537
E+ + YS++Y ++G + L IP+ T ++E L Y V A + G
Sbjct: 623 EKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDT-TKYLLEQLEKWTEYRITVTAHTDVG 681
Query: 1538 WGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER--PR 1595
G E V+ ++ P P P + A++ S+++SW P
Sbjct: 682 PGPESLSVLIRTNEDVPSGP----------------PRKVEVEAVNSTSVKVSWRSPVPN 725
Query: 1596 RPNGDIVGYLVTCEMAQGGGP-----------ATAFRVDGDSPESRLTVPGLSENVPYKF 1644
+ +G I GY V + G P A A D+ E + + GL Y
Sbjct: 726 KQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSL 785
Query: 1645 KVQARTTEGFG 1655
V A TT+G G
Sbjct: 786 TVTAYTTKGDG 796
Score = 85.9 bits (211), Expect = 3e-16
Identities = 138/636 (21%), Positives = 229/636 (36%), Gaps = 120/636 (18%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 384 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 443
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 444 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 501
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 502 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 554
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQ 1338
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 555 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP----------- 600
Query: 1339 SGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAA 1398
D SPS T LV+ + P + + T +
Sbjct: 601 -----------QDISCTSPS---------STSILVSWQ-----PPPVEKQNGIITEYSIK 635
Query: 1399 Y-GTHLSPHVPHRVLSTSSTLTR----------DYNSLTRSEHSHSTTLPRDYSTLTSVS 1447
Y PH +L S T+ +Y +T + H+ P S L
Sbjct: 636 YTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYR-ITVTAHTDVGPGPESLSVLI--- 691
Query: 1448 SHDSRLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH 1503
R VP P R V A+ TS++VSW+ P + ++GY V Y + GE
Sbjct: 692 ----RTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPK 747
Query: 1504 -------------RLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIES 1550
+ + + +++ L P SY V A + +G G + + +
Sbjct: 748 GQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT 807
Query: 1551 QVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEM 1610
P P LV ++ + W P G + GY +
Sbjct: 808 GAVPGKP------------------RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG- 848
Query: 1611 AQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGG 1670
+ P T ++ E T + + Y F++ AR GFG E I+I +
Sbjct: 849 RKDMEPLTT--LEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPT 906
Query: 1671 PFPQLGSRAGL--------FQHPLQSEYSSITTTHT 1698
FPQ G +Q P+ +E + I T +T
Sbjct: 907 GFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYT 942
Score = 70.9 bits (172), Expect = 1e-11
Identities = 97/432 (22%), Positives = 168/432 (38%), Gaps = 63/432 (14%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYW-IQGDSESEAHLLD--SKVPSV 1181
PQ+ + + S I +W PP +G Y +KY + G+ + +L S
Sbjct: 600 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKY 659
Query: 1182 ELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSW 1240
L L + +Y + V A+ G GP S V RT+++VPS P R + V+ST ++SW
Sbjct: 660 LLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSW 719
Query: 1241 AEPA--ETNGEITAYEVCYGLVNDDNRPIGPMKKVLV--------DNPKNRMLLIENLRE 1290
P + +G+I Y+V Y + + PM K ++ D+ ++I L+
Sbjct: 720 RSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQP 779
Query: 1291 SQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYS 1350
Y TV A G G ++PK + +P P + + + + +
Sbjct: 780 ETSYSLTVTAYTTKGDGAR--------SKPKLVSTTGAVPGKPRLVINHTQMNTALIQWH 831
Query: 1351 DDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHR 1410
V D L R+ F + +TT + H + H+
Sbjct: 832 PPV-------------DTFGPLQGYRLKFG----RKDMEPLTTLEFSEKEDHFTATDIHK 874
Query: 1411 VLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALG 1470
S L+ E ++P + T + H T+
Sbjct: 875 GASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTS--------------- 919
Query: 1471 PTSLRVSWQEP-RCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYV 1527
TS+++SWQ P ER + Y++ Y+ +N L + PA T++ + L P+ +Y
Sbjct: 920 -TSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYD 978
Query: 1528 FRVRAQSQEGWG 1539
+VRA + +G G
Sbjct: 979 VKVRAHTSKGPG 990
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 901 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 960
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 961 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1020
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1021 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1069
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1070 FVLTNRGNSAGG 1081
Score = 35.0 bits (79), Expect = 0.64
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
Query: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESR 1630
P PG V T + S+ L+W+ N + V Y + + +DG + +R
Sbjct: 310 PKPPGTPVVTESTATSITLTWDSG---NPEPVSYYIIQHKPKNSEELYK-EIDGVAT-TR 364
Query: 1631 LTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQ 1667
+V GLS Y+F+V A G GP E ++T S+
Sbjct: 365 YSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSE 401
>gi|222537743 protein tyrosine phosphatase, receptor type, Q [Homo
sapiens]
Length = 2299
Score = 94.7 bits (234), Expect = 7e-19
Identities = 117/495 (23%), Positives = 195/495 (39%), Gaps = 79/495 (15%)
Query: 1180 SVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLS 1239
S + L P+ ++ + V A+ GEGP +++S RT Q+VPS + + +SS+ L
Sbjct: 530 SYVIRRLVPFTEHMISVSAFTIMGEGP-PTVLSVRTRQQVPSSIKIINYKNISSSSILLY 588
Query: 1240 WAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVK 1299
W P NG+IT Y + Y + D NR + +DN LI L++ Y+ V
Sbjct: 589 WDPPEYPNGKITHYTI-YAMELDTNR---AFQITTIDN----SFLITGLKKYTKYKMRVA 640
Query: 1300 ARNGAGWGP-EREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPS 1358
A G E I + T P S P D+ ++D + +D++ S
Sbjct: 641 ASTHVGESSLSEENDIFVRTSEDEPESSP--QDVEVID-----------VTADEIRLKWS 687
Query: 1359 GSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTL 1418
++P+ ++ +D +L+ T++ +L PH + +
Sbjct: 688 PPEKPNGIIIAYEVLYKNID--------TLYMKNTSTTDIILRNLRPHTLYNI------- 732
Query: 1419 TRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDT-PTRLVFSALGPTSLRVS 1477
S TR H + S+L SV R + VPD+ P + + + + +S
Sbjct: 733 --SVRSYTRFGHGNQV------SSLLSV-----RTSETVPDSAPENITYKNISSGEIELS 779
Query: 1478 WQEPRCERP-LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQE 1536
+ P +Q Y++ + NG E +N + Q V++ Y+ V A + +
Sbjct: 780 FLPPSSPNGIIQKYTIYLKRSNGNEERTINTTSLTQNIKVLKKYT---QYIIEVSASTLK 836
Query: 1537 GWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRR 1596
G G + + + P SP P LS +++LSW+ P
Sbjct: 837 GEGVRSAPISILTEEDAPDSP----------------PQDFSVKQLSGVTVKLSWQPPLE 880
Query: 1597 PNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGP 1656
PNG I+ Y V V E+ L + L NV Y V A T G G
Sbjct: 881 PNGIILYYTV---YVWNRSSLKTINV----TETSLELSDLDYNVEYSAYVTASTRFGDGK 933
Query: 1657 EREGIITIESQDGGP 1671
R II+ ++ +G P
Sbjct: 934 TRSNIISFQTPEGAP 948
Score = 77.8 bits (190), Expect = 9e-14
Identities = 119/543 (21%), Positives = 210/543 (38%), Gaps = 90/543 (16%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKY--WIQGDSESEAHLLDSKVPSVELTNL 1186
AP+N K S +I ++LPPS P G KY +++ + +E +++ + + L
Sbjct: 762 APENITYKNISSGEIELSFLPPS-SPNGIIQKYTIYLKRSNGNEERTINTTSLTQNIKVL 820
Query: 1187 YPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAE 1245
Y Y ++V A +GEG S+ +S T ++ P S P + +S +LSW P E
Sbjct: 821 KKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSVKQLSGVTVKLSWQPPLE 880
Query: 1246 TNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAG 1305
NG I Y V + + N L + +L + Y V A G
Sbjct: 881 PNGIILYYTVY----------VWNRSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFG 930
Query: 1306 WGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSV 1365
G R II+ T P P +D + S ++ + +P
Sbjct: 931 DGKTRSNIISFQTPEGAPSDPP-------------KDVYYANLSSSSIILFWTPPSKP-- 975
Query: 1366 SDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSL 1425
NG + + S++ T+ GT + H V T D++++
Sbjct: 976 --------NGIIQY------YSVYYRNTS-----GTFMQNFTLHEV-------TNDFDNM 1009
Query: 1426 TRSEHSHSTTLPRDYS--TLTSVSSHDSRLTAGVPDTPT----------RLVFSALGPTS 1473
T S T+ Y+ S S + ++ + + T L + ++ T+
Sbjct: 1010 TVSTIIDKLTIFSYYTFWLTASTSVGNGNKSSDIIEVYTDQDIPEGFVGNLTYESISSTA 1069
Query: 1474 LRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQ 1533
+ VSW P L Y V +L H + S+ ++L Y+ ++
Sbjct: 1070 INVSWVPPAQPNGLVFYYVSL-ILQQTPRHVRPPLVTYERSIYFDNLEKYTDYILKITPS 1128
Query: 1534 SQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER 1593
+++G+ + I+++ +P ++ ++T F LS S+ LSW+
Sbjct: 1129 TEKGFSDTYTAQLYIKTEE-------DVPETSPIINT--------FKNLSSTSVLLSWDP 1173
Query: 1594 PRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEG 1653
P +PNG I+ Y +T QG +F + ++ + + LS Y F ART +G
Sbjct: 1174 PVKPNGAIISYDLT---LQGPNENYSF----ITSDNYIILEELSPFTLYSFFAAARTRKG 1226
Query: 1654 FGP 1656
GP
Sbjct: 1227 LGP 1229
Score = 72.4 bits (176), Expect = 4e-12
Identities = 128/563 (22%), Positives = 214/563 (38%), Gaps = 90/563 (15%)
Query: 1115 QMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMG---YRVKYWIQGDSESEA 1171
++ + Q P G +G N ++ S I+ +W+PP+ +P G Y V +Q
Sbjct: 1045 EVYTDQDIPEGFVG---NLTYESISSTAINVSWVPPA-QPNGLVFYYVSLILQQTPRHVR 1100
Query: 1172 HLLDSKVPSVELTNLYPYCDYEMKVCAYGAQG-EGPYSSLVSCRTHQEVP-SEPGRLAFN 1229
L + S+ NL Y DY +K+ +G Y++ + +T ++VP + P F
Sbjct: 1101 PPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEEDVPETSPIINTFK 1160
Query: 1230 VVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLR 1289
+SST LSW P + NG I +Y++ N++ I + +++E L
Sbjct: 1161 NLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFI----------TSDNYIILEELS 1210
Query: 1290 ESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMY 1349
Y + AR G GP +I+ T S+P+ P + D+ +L +
Sbjct: 1211 PFTLYSFFAAARTRKGLGP--SSILFFYTDE----SVPLAPPQNLTLINCTSDF-VWLKW 1263
Query: 1350 SDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPH 1409
S L P G + EH D + + + T A G
Sbjct: 1264 SPSPL--PGGIVKVYSFKIHEH----ETDTIYYKNISGF----KTEAKLVG--------- 1304
Query: 1410 RVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSAL 1469
L ST + ++ T+ + + +S + ++ +S VPD + A
Sbjct: 1305 --LEPVSTYSIRVSAFTKVGNGN------QFSNVVKFTTQES-----VPDVVQNMQCMAT 1351
Query: 1470 GPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1529
S+ V W P + G +Y + +++ + T + LL N SYVF+
Sbjct: 1352 SWQSVLVKWDPP---KKANGIITQYMVTVERNSTKVSPQDHMYTFI---KLLANTSYVFK 1405
Query: 1530 VRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQL 1589
VRA + G G ES H S + PS P + F+ + S L
Sbjct: 1406 VRASTSAGEGD--------ESTCHV---------STLPETVPSVPTNIAFSDVQSTSATL 1448
Query: 1590 SWERPRRPNGDIVGYLVTCEMAQ------GGGPATAFRVDGDSPESRL---TVPGLSENV 1640
+W RP G Y +T ++ ++ E+ L TV GL +
Sbjct: 1449 TWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEETVYGLKKFR 1508
Query: 1641 PYKFKVQARTTEGFGPEREGIIT 1663
Y+F+V A T G+G I T
Sbjct: 1509 WYRFQVAASTNAGYGNASNWIST 1531
Score = 71.6 bits (174), Expect = 6e-12
Identities = 127/558 (22%), Positives = 217/558 (38%), Gaps = 90/558 (16%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYP 1188
+PQ+ + +I W PP KP G + Y + + ++ ++ + L NL P
Sbjct: 668 SPQDVEVIDVTADEIRLKWSPPE-KPNGIIIAYEVLYKNIDTLYMKNTSTTDIILRNLRP 726
Query: 1189 YCDYEMKVCAYGAQGEG-PYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAET 1246
+ Y + V +Y G G SSL+S RT + VP S P + + +SS +LS+ P+
Sbjct: 727 HTLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENITYKNISSGEIELSFLPPSSP 786
Query: 1247 NGEITAYEVCYGLVN-DDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAG 1305
NG I Y + N ++ R I L N I+ L++ Y V A G
Sbjct: 787 NGIIQKYTIYLKRSNGNEERTINTTS--LTQN-------IKVLKKYTQYIIEVSASTLKG 837
Query: 1306 WGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSV 1365
G R A I++ T+ P S P D ++ SG
Sbjct: 838 EGV-RSAPISILTEEDAPDSPP----------------------QDFSVKQLSG------ 868
Query: 1366 SDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTR-DYNS 1424
V ++ + P N + T Y + S V TS L+ DYN
Sbjct: 869 -------VTVKLSWQPPLEPNGIILYYTV----YVWNRSSLKTINVTETSLELSDLDYN- 916
Query: 1425 LTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSA-LGPTSLRVSWQEPRC 1483
+ S + ++T D T +++ S + G P P + V+ A L +S+ + W P
Sbjct: 917 VEYSAYVTASTRFGDGKTRSNIISFQT--PEGAPSDPPKDVYYANLSSSSIILFWTPP-- 972
Query: 1484 ERP---LQGYSVEYQLLNGGELHRLNIPNPAQ------TSVVVEDLLPNHSYVFRVRAQS 1534
+P +Q YSV Y+ +G + + S +++ L Y F + A +
Sbjct: 973 SKPNGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTAST 1032
Query: 1535 QEGWGREREGVITIES-QVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER 1593
G G + +I + + Q P+ + G L + ++S ++ +SW
Sbjct: 1033 SVGNGNKSSDIIEVYTDQDIPEGFV----------------GNLTYESISSTAINVSWVP 1076
Query: 1594 PRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEG 1653
P +PNG +V Y V+ + Q R + E + L + Y K+ T +G
Sbjct: 1077 PAQPNG-LVFYYVSLILQQ---TPRHVRPPLVTYERSIYFDNLEKYTDYILKITPSTEKG 1132
Query: 1654 FGPEREGIITIESQDGGP 1671
F + I++++ P
Sbjct: 1133 FSDTYTAQLYIKTEEDVP 1150
Score = 67.4 bits (163), Expect = 1e-10
Identities = 108/462 (23%), Positives = 175/462 (37%), Gaps = 68/462 (14%)
Query: 1181 VELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
V+++N+ P Y++ + + P + +V+ T+ P P LA V S LSW
Sbjct: 19 VDVSNVVPGTRYDITISSISTTYTSPVTRIVT--TNVTKPGPPVFLAGERVGSAGILLSW 76
Query: 1241 AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
P NG I +Y V Y V + + + P + +L+ NL Y V A
Sbjct: 77 NTPPNPNGRIISYIVKYKEVCPWMQTVYTQVR---SKPDSLEVLLTNLNPGTTYEIKVAA 133
Query: 1301 RNGAGWGPEREA------------IINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLM 1348
N AG G + ++NL + ++ +I +P Q SF +
Sbjct: 134 ENSAGIGVFSDPFLFQTAESAPGKVVNLTVEAYNASAVKLIWYLP---RQPNGKITSFKI 190
Query: 1349 YSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVP 1408
V + SG VS E ++ G++ S + L +T S + ++P P
Sbjct: 191 ---SVKHARSGIVVKDVSIRVEDILTGKLPECNENSESFL--WSTASPSPTLGRVTP--P 243
Query: 1409 HRVLSTSSTLTR-DYNSLTRSEHSHSTTLPRDYSTL--------TSVSSHDS---RLTAG 1456
R +SSTLT+ + +S+ + S T R Y+T T DS R
Sbjct: 244 SRTTHSSSTLTQNEISSVWKEPISFVVTHLRPYTTYLFEVSAATTEAGYIDSTIVRTPES 303
Query: 1457 VPDTPTR-LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1515
VP+ P + V + S + W P Y VE G R+ +
Sbjct: 304 VPEGPPQNCVTGNITGKSFSILWDPPTIVTGKFSYRVELY----GPSGRILDNSTKDLKF 359
Query: 1516 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1575
+L P Y + A++ G G P+S + S FT P PG
Sbjct: 360 AFTNLTPFTMYDVYIAAETSAGTG--------------PKSNI-----SVFT--PPDVPG 398
Query: 1576 P---LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG 1614
L + ++++W++PR+PNG I Y V + + G
Sbjct: 399 AVFDLQLAEVESTQVRITWKKPRQPNGIINQYRVKVLVPETG 440
Score = 53.9 bits (128), Expect = 1e-06
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 14/138 (10%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKY-----WIQGDSESEAHLLDSKVP 1179
G P + GS I +W P +G+ + Y VKY W+Q + + SK
Sbjct: 57 GPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQ----TVYTQVRSKPD 112
Query: 1180 SVE--LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQ 1237
S+E LTNL P YE+KV A + G G +S +T + P + L +++ +
Sbjct: 113 SLEVLLTNLNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVVNLTVEAYNASAVK 172
Query: 1238 LSWAEPAETNGEITAYEV 1255
L W P + NG+IT++++
Sbjct: 173 LIWYLPRQPNGKITSFKI 190
Score = 51.6 bits (122), Expect = 7e-06
Identities = 56/239 (23%), Positives = 101/239 (42%), Gaps = 21/239 (8%)
Query: 1114 SQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPS--GKPMGYRVKYWIQGDSESEA 1171
S +S++ P G P+N + A I +W P+ P Y + + E
Sbjct: 1526 SNWISTKTLPGPPDGPPENVHVVATSPFSISISWSEPAVITGPTCYLIDVKSVDNDEFNI 1585
Query: 1172 HLLDS--KVPSVELTNLYPYCDYEMKVCAY-----GAQGEGPYSSLVSCRTHQEVPSE-P 1223
+ S + ++E+ +L + Y + + A+ A EG S+ + T + P + P
Sbjct: 1586 SFIKSNEENKTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEMIVTTLESAPKDPP 1645
Query: 1224 GRLAFNVVSSTVT--QLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNR 1281
+ F + VT QL++ P++ NG I Y+ + +D+ + + + N
Sbjct: 1646 NNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQAL--VYREDDPTAVQIHNLSIIQKTNT 1703
Query: 1282 ML--LIENLRESQPYRYTVKARNGAGWGPEREAIINLATQ-PKRPMSIPIIPDIPIVDA 1337
+ ++E L+ Y +V A N AG GP+ I + + P RP + P PI DA
Sbjct: 1704 FVIAMLEGLKGGHTYNISVYAVNSAGAGPKVPMRITMDIKAPARPKTKP----TPIYDA 1758
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEAHLLDSKVPSVEL- 1183
G PQN + W PP+ GK YRV+ + G S +LD+ ++
Sbjct: 307 GPPQNCVTGNITGKSFSILWDPPTIVTGK-FSYRVELY--GPS---GRILDNSTKDLKFA 360
Query: 1184 -TNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAE 1242
TNL P+ Y++ + A + G GP S+ +S T +VP L V ST +++W +
Sbjct: 361 FTNLTPFTMYDVYIAAETSAGTGPKSN-ISVFTPPDVPGAVFDLQLAEVESTQVRITWKK 419
Query: 1243 PAETNGEITAYEV 1255
P + NG I Y V
Sbjct: 420 PRQPNGIINQYRV 432
Score = 47.8 bits (112), Expect = 1e-04
Identities = 54/234 (23%), Positives = 87/234 (37%), Gaps = 21/234 (8%)
Query: 1109 DRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSE 1168
D S ++S Q P P++ S I W PPS KP G Y + +
Sbjct: 931 DGKTRSNIISFQTPEGAPSDPPKDVYYANLSSSSIILFWTPPS-KPNGIIQYYSVYYRNT 989
Query: 1169 SEAHL-----------LDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSS-LVSCRTH 1216
S + D+ S + L + Y + A + G G SS ++ T
Sbjct: 990 SGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGNKSSDIIEVYTD 1049
Query: 1217 QEVPSE-PGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLV 1275
Q++P G L + +SST +SW PA+ NG + Y ++ R + P
Sbjct: 1050 QDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSL--ILQQTPRHVRPPLVTY- 1106
Query: 1276 DNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPII 1329
R + +NL + Y + G+ A + + T+ P + PII
Sbjct: 1107 ----ERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEEDVPETSPII 1156
Score = 41.2 bits (95), Expect = 0.009
Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 11/101 (10%)
Query: 1562 PGSAFTLSTPSAPGPLVFTA---LSPDSLQLSWERPRRPNGDIVGYLV----TCEMAQGG 1614
P + + + PGP VF A + + LSW P PNG I+ Y+V C Q
Sbjct: 44 PVTRIVTTNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQ-- 101
Query: 1615 GPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFG 1655
T R DS E LT L+ Y+ KV A + G G
Sbjct: 102 TVYTQVRSKPDSLEVLLT--NLNPGTTYEIKVAAENSAGIG 140
Score = 41.2 bits (95), Expect = 0.009
Identities = 96/485 (19%), Positives = 159/485 (32%), Gaps = 108/485 (22%)
Query: 1136 KAAGSRKIHFNWLPPSGKPMGYRVKY--WIQGDSESEAHLLDSKVPSVELTNLYPYCDYE 1193
K S + +W PP KP G + Y +QG +E+ + + + L L P+ Y
Sbjct: 1160 KNLSSTSVLLSWDPPV-KPNGAIISYDLTLQGPNENYSFITSDNY--IILEELSPFTLYS 1216
Query: 1194 MKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAETNGEITA 1252
A +G GP SS++ T + VP + P L +S L W+ G +
Sbjct: 1217 FFAAARTRKGLGP-SSILFFYTDESVPLAPPQNLTLINCTSDFVWLKWSPSPLPGGIVKV 1275
Query: 1253 YEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREA 1312
Y +++ K + + +++ +E + Y V A G G +
Sbjct: 1276 YSF---KIHEHETDTIYYKNISGFKTEAKLVGLEPV---STYSIRVSAFTKVGNGNQFSN 1329
Query: 1313 IINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHL 1372
++ TQ +PD+ + S L+ D
Sbjct: 1330 VVKFTTQES-------VPDVVQNMQCMATSWQSVLVKWDP-------------------- 1362
Query: 1373 VNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSP----HVPHRVLSTSSTLTRDYNSLTRS 1428
P N + + T +SP + ++L+ +S + + S +
Sbjct: 1363 ---------PKKANGIITQYMVTVERNSTKVSPQDHMYTFIKLLANTSYVFKVRASTSAG 1413
Query: 1429 EHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEP------- 1481
E ST H S L VP PT + FS + TS ++W P
Sbjct: 1414 EGDESTC-------------HVSTLPETVPSVPTNIAFSDVQSTSATLTWIRPDTILGYF 1460
Query: 1482 ------------RCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1529
+C+ VEYQ + L+ ++ T V L Y F+
Sbjct: 1461 QNYKITTQLRAQKCKEWESEECVEYQKIQ--YLYEAHL-----TEETVYGLKKFRWYRFQ 1513
Query: 1530 VRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQL 1589
V A + G+G + T P P P + A SP S+ +
Sbjct: 1514 VAASTNAGYGNASNWISTKTLPGPPDGP----------------PENVHVVATSPFSISI 1557
Query: 1590 SWERP 1594
SW P
Sbjct: 1558 SWSEP 1562
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 92.8 bits (229), Expect = 3e-18
Identities = 131/542 (24%), Positives = 214/542 (39%), Gaps = 83/542 (15%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 326 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 385
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 386 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 445
Query: 1248 GEITAYEVCYGLVNDDNRPIGP-MKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
G+I Y V Y + D + + MK + D +++ I NL + Y V A G
Sbjct: 446 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD---SQITTIGNLVPQKTYSVKVLAFTSIGD 500
Query: 1307 GPEREAIINLATQ---PKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRP 1363
GP + I + TQ P +P++ P + ++ ++ S RS + +
Sbjct: 501 GP-LSSDIQVITQTGVPGQPLNFKAEP-----------ESETSILLSWTPPRSDTIANYE 548
Query: 1364 SVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYN 1423
V D EH R+ PG++ L + S Y L+ P + ++++ ++
Sbjct: 549 LVYKDGEHGEEQRITIE-PGTSYRLQGLKPNS--LYYFRLAARSPQGLGASTAEIS---- 601
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRC 1483
R+ S + P+D S TS SS TS+ VSWQ P
Sbjct: 602 --ARTMQSKPSAPPQDIS-CTSPSS-----------------------TSILVSWQPPPV 635
Query: 1484 ERP---LQGYSVEYQLLNGGE---LHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEG 1537
E+ + YS++Y ++G + L IP+ T ++E L Y V A + G
Sbjct: 636 EKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDT-TKYLLEQLEKWTEYRITVTAHTDVG 694
Query: 1538 WGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWER--PR 1595
G E V+ ++ P P P + A++ S+++SW P
Sbjct: 695 PGPESLSVLIRTNEDVPSGP----------------PRKVEVEAVNSTSVKVSWRSPVPN 738
Query: 1596 RPNGDIVGYLVTCEMAQGGGPATAFRVDGD--SPESRLTVPGLSENVPYKFKVQARTTEG 1653
+ +G I GY V + G P + + + + GL Y V A TT+G
Sbjct: 739 KQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKG 798
Query: 1654 FG 1655
G
Sbjct: 799 DG 800
Score = 86.7 bits (213), Expect = 2e-16
Identities = 138/627 (22%), Positives = 228/627 (36%), Gaps = 111/627 (17%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 397 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 456
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 457 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 514
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 567
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQ 1338
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 568 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP----------- 613
Query: 1339 SGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAA 1398
D SPS T LV+ + P + + T +
Sbjct: 614 -----------QDISCTSPS---------STSILVSWQ-----PPPVEKQNGIITEYSIK 648
Query: 1399 Y-GTHLSPHVPHRVLSTSSTLTR----------DYNSLTRSEHSHSTTLPRDYSTLTSVS 1447
Y PH +L S T+ +Y +T + H+ P S L
Sbjct: 649 YTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYR-ITVTAHTDVGPGPESLSVLI--- 704
Query: 1448 SHDSRLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH 1503
R VP P R V A+ TS++VSW+ P + ++GY V Y + GE
Sbjct: 705 ----RTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPK 760
Query: 1504 RLNIPNPAQTS----VVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLC 1559
+ + +++ L P SY V A + +G G + + + P P
Sbjct: 761 GQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP-- 818
Query: 1560 PLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATA 1619
LV ++ + W P G + GY + + P T
Sbjct: 819 ----------------RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG-RKDMEPLTT 861
Query: 1620 FRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1679
++ E T + + Y F++ AR GFG E I+I + FPQ
Sbjct: 862 --LEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSE 919
Query: 1680 GL--------FQHPLQSEYSSITTTHT 1698
G +Q P+ +E + I T +T
Sbjct: 920 GTTSTSVQLSWQPPVLAERNGIITKYT 946
Score = 73.6 bits (179), Expect = 2e-12
Identities = 112/490 (22%), Positives = 185/490 (37%), Gaps = 90/490 (18%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
G P N A+ I +W PP + + G+ E + S L L
Sbjct: 517 GQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLK 576
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSWAEPA-- 1244
P Y ++ A QG G ++ +S RT Q PS P + ++ SST +SW P
Sbjct: 577 PNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVE 636
Query: 1245 ETNGEITAYEVCYGLVN-DDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNG 1303
+ NG IT Y + Y V+ +D++P ++L L+E L + YR TV A
Sbjct: 637 KQNGIITEYSIKYTAVDGEDDKP----HEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 692
Query: 1304 AGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQS----------GEDYDSFLMYSDDV 1353
G GPE +++ + T P P ++ V++ S + + Y
Sbjct: 693 VGPGPESLSVL-IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHY 751
Query: 1354 LRSPSGSQR--PSVSDDTEHLVNGRMDFAFPG-STNSLHRMTTTSAAAYG---------- 1400
+R +G + P + D ++ D G + + +T T+ G
Sbjct: 752 VRMENGEPKGQPMLKDV---MLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLV 808
Query: 1401 --THLSPHVPHRVLSTSSTLT------------------------RDYNSLTRSEHSHST 1434
T P P V++ + T +D LT E S
Sbjct: 809 STTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEK- 867
Query: 1435 TLPRDYSTLTSV---SSHDSRLTA--------------GVPDT-----PTRLVFSALGPT 1472
D+ T T + +S+ RL+A +P+ P L T
Sbjct: 868 ---EDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTST 924
Query: 1473 SLRVSWQEP-RCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1529
S+++SWQ P ER + Y++ Y+ +N L + PA T++ + L P+ +Y +
Sbjct: 925 SVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVK 984
Query: 1530 VRAQSQEGWG 1539
VRA + +G G
Sbjct: 985 VRAHTSKGPG 994
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 905 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 964
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 965 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1024
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1025 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1073
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1074 FVLTNRGNSAGG 1085
Score = 35.0 bits (79), Expect = 0.64
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
Query: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESR 1630
P PG V T + S+ L+W+ N + V Y + + +DG + +R
Sbjct: 323 PKPPGTPVVTESTATSITLTWDSG---NPEPVSYYIIQHKPKNSEELYK-EIDGVAT-TR 377
Query: 1631 LTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQ 1667
+V GLS Y+F+V A G GP E ++T S+
Sbjct: 378 YSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSE 414
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 567 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 615
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 616 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 665
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 666 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 716
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 717 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 767
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 589 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 641
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 642 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 690
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 691 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 736
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 737 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 794
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 795 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 536 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 587
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 588 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 638
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 639 CVKGECHCSTGWGGVNCE 656
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 566 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 614
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 615 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 664
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 665 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 715
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 716 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 766
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 588 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 640
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 641 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 689
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 690 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 735
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 736 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 793
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 794 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 839
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 535 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 586
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 587 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 637
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 638 CVKGECHCSTGWGGVNCE 655
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 567 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 615
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 616 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 665
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 666 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 716
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 717 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 767
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 589 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 641
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 642 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 690
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 691 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 736
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 737 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 794
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 795 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 536 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 587
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 588 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 638
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 639 CVKGECHCSTGWGGVNCE 656
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,707,106
Number of Sequences: 37866
Number of extensions: 3807239
Number of successful extensions: 15200
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 276
Number of HSP's that attempted gapping in prelim test: 9996
Number of HSP's gapped (non-prelim): 3216
length of query: 1752
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1636
effective length of database: 13,855,062
effective search space: 22666881432
effective search space used: 22666881432
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.