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Search of human proteins with 54607027
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
(1805 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 3720 0.0
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 3582 0.0
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 3465 0.0
gi|47078292 integrin beta chain, beta 3 precursor [Homo sapiens] 450 e-126
gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens] 447 e-125
gi|19743815 integrin beta 1 isoform 1B precursor [Homo sapiens] 447 e-125
gi|19743813 integrin beta 1 isoform 1A precursor [Homo sapiens] 447 e-125
gi|19743823 integrin beta 1 isoform 1A precursor [Homo sapiens] 447 e-125
gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens] 447 e-125
gi|19743819 integrin beta 1 isoform 1D precursor [Homo sapiens] 447 e-125
gi|20127446 integrin, beta 5 [Homo sapiens] 436 e-121
gi|9625002 integrin, beta 6 [Homo sapiens] 433 e-121
gi|188595677 integrin, beta 2 precursor [Homo sapiens] 394 e-109
gi|89191865 integrin, beta 2 precursor [Homo sapiens] 394 e-109
gi|4504777 integrin, beta 7 [Homo sapiens] 387 e-107
gi|4504779 integrin, beta 8 precursor [Homo sapiens] 323 1e-87
gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 140 1e-32
gi|119220552 sidekick 1 [Homo sapiens] 97 1e-19
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 97 1e-19
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 96 3e-19
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 96 3e-19
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 95 5e-19
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 95 7e-19
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 92 3e-18
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 92 6e-18
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 92 6e-18
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 91 8e-18
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 91 8e-18
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 91 8e-18
gi|153946395 tenascin C precursor [Homo sapiens] 91 1e-17
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 3720 bits (9646), Expect = 0.0
Identities = 1805/1805 (100%), Positives = 1805/1805 (100%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
Query: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY
Sbjct: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
Query: 1441 STLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPSW 1500
STLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPSW
Sbjct: 1441 STLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPSW 1500
Query: 1501 GPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI 1560
GPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI
Sbjct: 1501 GPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI 1560
Query: 1561 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT 1620
PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT
Sbjct: 1561 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT 1620
Query: 1621 LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1680
LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP
Sbjct: 1621 LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1680
Query: 1681 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1740
ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ
Sbjct: 1681 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1740
Query: 1741 SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ 1800
SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ
Sbjct: 1741 SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ 1800
Query: 1801 QFFQT 1805
QFFQT
Sbjct: 1801 QFFQT 1805
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 3582 bits (9289), Expect = 0.0
Identities = 1752/1805 (97%), Positives = 1752/1805 (97%), Gaps = 53/1805 (2%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA 1380
Query: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY
Sbjct: 1381 FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY 1440
Query: 1441 STLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPSW 1500
STLTSVSSH
Sbjct: 1441 STLTSVSSH--------------------------------------------------- 1449
Query: 1501 GPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI 1560
DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI
Sbjct: 1450 --DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI 1507
Query: 1561 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT 1620
PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT
Sbjct: 1508 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT 1567
Query: 1621 LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1680
LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP
Sbjct: 1568 LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1627
Query: 1681 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1740
ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ
Sbjct: 1628 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1687
Query: 1741 SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ 1800
SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ
Sbjct: 1688 SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ 1747
Query: 1801 QFFQT 1805
QFFQT
Sbjct: 1748 QFFQT 1752
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 3465 bits (8984), Expect = 0.0
Identities = 1723/1877 (91%), Positives = 1728/1877 (92%), Gaps = 127/1877 (6%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT----------- 1369
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG 1380
Query: 1370 EHLVNGRMDFAFP------------------------------GSTNSLHRMTTTSAAAY 1399
E L R+ + P G SL R T
Sbjct: 1381 EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPP-- 1438
Query: 1400 GTHL-----------SPHVPHRVLSTS--------------------STLTRDYNSLTRS 1428
G HL S + HR+ +TS STLTRDYNSLTRS
Sbjct: 1439 GEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRS 1498
Query: 1429 EHSHSTTLPRDYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDS 1488
EHSHSTTLPRDYSTLTSVSSH
Sbjct: 1499 EHSHSTTLPRDYSTLTSVSSH--------------------------------------- 1519
Query: 1489 IILAGRPAAPSWGPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQ 1548
DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQ
Sbjct: 1520 --------------DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQ 1565
Query: 1549 LLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQ 1608
LLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQ
Sbjct: 1566 LLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQ 1625
Query: 1609 SPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGG 1668
SPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGG
Sbjct: 1626 SPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGG 1685
Query: 1669 PATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL 1728
PATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL
Sbjct: 1686 PATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL 1745
Query: 1729 GSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTL 1788
GSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTL
Sbjct: 1746 GSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTL 1805
Query: 1789 TTSGTLSTHMDQQFFQT 1805
TTSGTLSTHMDQQFFQT
Sbjct: 1806 TTSGTLSTHMDQQFFQT 1822
>gi|47078292 integrin beta chain, beta 3 precursor [Homo sapiens]
Length = 788
Score = 450 bits (1158), Expect = e-126
Identities = 272/761 (35%), Positives = 404/761 (53%), Gaps = 49/761 (6%)
Query: 2 AGPRPSP-WARLL-LAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFR-- 57
A PRP P WA +L L AL V + G N C V SC +C+ V CA+C+DE
Sbjct: 3 ARPRPRPLWATVLALGALAGVGVGGP--NICTTRGVSSCQQCLAVSPMCAWCSDEALPLG 60
Query: 58 DRRCNTQAELLAAGCQRESIVVMESSFQITEETQIDT-----TLRRSQMSPQGLRVRLRP 112
RC+ + LL C ESI S ++ E+ + + + +Q+SPQ + +RLRP
Sbjct: 61 SPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRP 120
Query: 113 GEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFG 172
+ ++F ++V + + PVD+Y LMD S SM DDL +++ +G LA + +LTS+ IGFG
Sbjct: 121 DDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFG 180
Query: 173 KFVDKVSVPQTDMRP-EKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISG 227
FVDK P + P E L+ P + P F +K+V++LT+ V F +++ + +S
Sbjct: 181 AFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSR 240
Query: 228 NLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDER 287
N DAPEGGFDAI+Q VC IGWR D++HLLVF+T++ H DG LAGI+ ND +
Sbjct: 241 NRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGR--LAGIVQPNDGQ 298
Query: 288 CHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGV 347
CH+ + Y+ T DYPS+ + L++ NI IFAVT + Y+ P +++GV
Sbjct: 299 CHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGV 358
Query: 348 LQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKT----RTGSFHIRRG 403
L DSSN+++L+ +A+ +IRS +++ D P L + ++ G
Sbjct: 359 LSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIG 418
Query: 404 EVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKE 462
+ + ++ + V P++++ + +KP F D L + CD C C+ Q E
Sbjct: 419 DTVSFSIEAK---------VRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCD-CACQAQAE 468
Query: 463 VRSARCSF-NGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGEC 518
S RC+ NG F CG C C GW G C CS Q REG+ CS RGEC
Sbjct: 469 PNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPV-CSQRGEC 527
Query: 519 QCGHCVCYGE--GRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCP 576
CG CVC+ G+ G++CE D+F C R G +C+ G+CS G C+C+ WTG C+C
Sbjct: 528 LCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCT 587
Query: 577 LSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQ 636
TC+ SNG +C+GRG CECG C C Q Y DT CE P C + CV+C+
Sbjct: 588 TRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDT-CE--KCPTCPDACTFKKECVECK 644
Query: 637 AWGTGE-KKGRTCEE-CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGP 694
+ G TC C +++ V ELK + V C++++E DDC + D +
Sbjct: 645 KFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNE-DDCVVRFQYYEDSS--G 701
Query: 695 NSTVLVHKKKDCPPGSFWWLIPLLLL-LLPLLALLLLLCWK 734
S + V ++ +CP G ++ L ++ + L+ L LL WK
Sbjct: 702 KSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWK 742
>gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens]
Length = 825
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743815 integrin beta 1 isoform 1B precursor [Homo sapiens]
Length = 789
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743813 integrin beta 1 isoform 1A precursor [Homo sapiens]
Length = 798
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743823 integrin beta 1 isoform 1A precursor [Homo sapiens]
Length = 798
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens]
Length = 819
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743819 integrin beta 1 isoform 1D precursor [Homo sapiens]
Length = 801
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|20127446 integrin, beta 5 [Homo sapiens]
Length = 799
Score = 436 bits (1120), Expect = e-121
Identities = 273/768 (35%), Positives = 390/768 (50%), Gaps = 68/768 (8%)
Query: 6 PSP-WARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRD-----R 59
P+P +A LL + L+G N C SC EC+ + CA+C+ E F
Sbjct: 5 PAPLYACLLGLCALLPRLAGL--NICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITS 62
Query: 60 RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRS------QMSPQGLRVRLRPG 113
RC+ +A L+ GC E I SSF + + + S QM+PQ + V LRPG
Sbjct: 63 RCDLRANLVKNGCGGE-IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPG 121
Query: 114 EERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGK 173
++ F+L+V + + PVDLY LMD S SM DDLDN++ +G LA + +LTS++ +GFG
Sbjct: 122 DKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGS 181
Query: 174 FVDKVSVPQTDMRPEKLKEP------WPNSDPPFSFKNVISLTEDVDEFRNKLQGERISG 227
FVDK P + P P +PN P F F++++ LT+ VD F +++ +R+S
Sbjct: 182 FVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSR 241
Query: 228 NLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDER 287
N DAPEGGFDA+LQ AVC IGWR D+ HLLVF+T+ H DG L G++ +D +
Sbjct: 242 NRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGK--LGGLVQPHDGQ 299
Query: 288 CHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGV 347
CHL+ YT DYPS+ L LA++NI IFAVT Y Y+ P +++ +
Sbjct: 300 CHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEI 359
Query: 348 LQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVT-------SKMFQKTRTGSFHI 400
L DS NI++L+ A+N IRS +++ D P L T S Q+ G +
Sbjct: 360 LDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEG---L 416
Query: 401 RRGEVGIYQVQLRA-------LEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIIC 452
+ G+ ++V L A EHV L+P F D L++ C
Sbjct: 417 KIGDTASFEVSLEARSCPSRHTEHV---------------FALRPVGFRDSLEVGVTYNC 461
Query: 453 DVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDI-QPCLREGEDKP 511
C C + E SARC+ +G +VCG C CS G+ G C C G + Q RE E KP
Sbjct: 462 -TCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKP 520
Query: 512 -CSGRGECQCGHCVCYGE--GRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGW 568
CSGRG+C C C C+ G+ G FCE DNF C R G LC+ G C G+C C G+
Sbjct: 521 LCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGY 580
Query: 569 TGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCED 628
G +C+C +TC +G IC+ RGHC CG+C C + + + +CE P C
Sbjct: 581 IGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEPGAFGE-MCE--KCPTCPDACST 637
Query: 629 LRSCVQCQAWGTGEKKGRTCEE-CNFKV-KMVDELKRAEEVVVRCSFRDEDDDCTYSYTM 686
R CV+C +G+ +TC C +V VD + + ++ V C ++ DC +T
Sbjct: 638 KRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTA-KDCVMMFTY 696
Query: 687 EGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLLLLPLLALLLLLCWK 734
+ N TVL + P + L+ ++ +L L+ L LL WK
Sbjct: 697 VELPSGKSNLTVLREPECGNTPNAMTILLAVVGSIL-LVGLALLAIWK 743
>gi|9625002 integrin, beta 6 [Homo sapiens]
Length = 788
Score = 433 bits (1113), Expect = e-121
Identities = 248/733 (33%), Positives = 385/733 (52%), Gaps = 52/733 (7%)
Query: 30 CKKAPVKSCTECVRVDKDCAYCTDEMFRD-----RRCNTQAELLAAGCQRESIVVMESSF 84
C ++C +C+ + CA+C E F RC+T A LLA GCQ I S
Sbjct: 23 CALGGAETCEDCLLIGPQCAWCAQENFTHPSGVGERCDTPANLLAKGCQLNFIENPVSQV 82
Query: 85 QITEETQIDTTLRRS-----QMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFS 139
+I + + +++ Q++PQ L ++LRPG + ++ V + + PVDLY LMD S
Sbjct: 83 EILKNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLYYLMDLS 142
Query: 140 NSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWPNSD- 198
SM DDL+ +K++G L++ +S+LTS++ +GFG FV+K P PE++ P +
Sbjct: 143 ASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPY 202
Query: 199 ---PPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDS 255
P F FK+++ LT D + F ++ ++IS N+D PEGGFDAI+Q AVC IGWR DS
Sbjct: 203 FCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDS 262
Query: 256 THLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLA 315
HLLVF +++ H+ D LAGI+ ND CHLD+ Y+ +YP++ L+ L
Sbjct: 263 LHLLVFVSDADSHFGMDSK--LAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLV 320
Query: 316 KHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLDIRAL 375
++N++ IFAVT YE P +++G+LQ+DS NI++L+ A+ +RS +++ L
Sbjct: 321 QNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVL 380
Query: 376 DSPRGLRTEVTS-----KMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQ 430
GL T+ +FQ + S H++ G+ + V + + H E +
Sbjct: 381 GDTEGLNLSFTAICNNGTLFQHQKKCS-HMKVGDTASFSVTVN-IPHC---------ERR 429
Query: 431 KGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARCSF-NGDFVCGQCVCSEGWSGQ 488
+I +KP D L++ C+ C C+ + EV S++C NG F CG C C G G
Sbjct: 430 SRHIIIKPVGLGDALELLVSPECN-CDCQKEVEVNSSKCHHGNGSFQCGVCACHPGHMGP 488
Query: 489 TCNCSTGSLSDIQPCLREGEDKP-CSGRGECQCGHCVCYGE--GRYEGQFCEYDNFQCPR 545
C C LS +E D P CSGRG+C CG C+C+ G G +C+ DNF C R
Sbjct: 489 RCECGEDMLST--DSCKEAPDHPSCSGRGDCYCGQCICHLSPYGNIYGPYCQCDNFSCVR 546
Query: 546 TSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQ 605
G LC G C G+CVC GWTG C+C S +C+ +G +C+GRG C CG+C C
Sbjct: 547 HKGLLCGGNGDCDCGECVCRSGWTGEYCNCTTSTDSCVSEDGVLCSGRGDCVCGKCVCTN 606
Query: 606 QSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKR-A 664
T CE + P C RSC++C G+ + ++C + E + +
Sbjct: 607 PGASGPT-CERCPTCGDP--CNSKRSCIECHLSAAGQAREECVDKCKLAGATISEEEDFS 663
Query: 665 EEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCP-PGSFWWLIPLLLLL 721
++ V CS + E ++C ++ + D ++H +KDCP P + ++ + L
Sbjct: 664 KDGSVSCSLQGE-NECLITFLITTDN----EGKTIIHSINEKDCPKPPNIPMIMLGVSLA 718
Query: 722 LPLLALLLLLCWK 734
+ L+ ++LL WK
Sbjct: 719 ILLIGVVLLCIWK 731
>gi|188595677 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 394 bits (1012), Expect = e-109
Identities = 273/805 (33%), Positives = 399/805 (49%), Gaps = 73/805 (9%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR- 59
M G RP LLA + +SL L+ C K V SC EC+ C +C F
Sbjct: 1 MLGLRPP-----LLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPG 55
Query: 60 -----RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGE 114
RC+T+ +LL GC + I+ S ETQ D + Q+SPQ + + LRPG+
Sbjct: 56 DPDSIRCDTRPQLLMRGCAADDIMDPTS----LAETQEDHNGGQKQLSPQKVTLYLRPGQ 111
Query: 115 ERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKF 174
F + P+DLY LMD S SM DDL N+KK+G +L R L+++T IGFG F
Sbjct: 112 AAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSF 171
Query: 175 VDKVSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLD 230
VDK +P + P+KL+ P PN + PPF+F++V+ LT + ++F+ ++ + ISGNLD
Sbjct: 172 VDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLD 231
Query: 231 APEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHL 290
APEGG DA++Q A C +IGWR + T LLVF+T+ FH+ DG L I++ ND RCHL
Sbjct: 232 APEGGLDAMMQVAACPEEIGWR-NVTRLLVFATDDGFHFAGDGK--LGAILTPNDGRCHL 288
Query: 291 DTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQE 350
+ Y + DYPSV L LA++NI PIFAVT+ YEKL P S++G L E
Sbjct: 289 E-DNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSE 347
Query: 351 DSSNIVELLEEAFNRIRSN--LDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIY 408
DSSN+V+L++ A+N++ S LD AL +VT F + RG+
Sbjct: 348 DSSNVVQLIKNAYNKLSSRVFLDHNALPD----TLKVTYDSFCSNGVTHRNQPRGDCDGV 403
Query: 409 QVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARC 468
Q+ + V T + ++Q I F+D + + C+ C C Q RS C
Sbjct: 404 QINVPITFQVKVT-ATECIQEQSFVIRAL-GFTDIVTVQVLPQCE-CRCRDQSRDRSL-C 459
Query: 469 SFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQ---PCLREGEDKPCSGRGECQCGHCVC 525
G CG C C G+ G+ C C T S + C ++ CSG G+C CG C+C
Sbjct: 460 HGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLC 519
Query: 526 Y-----GEGRYEGQFCEYDNFQCPRTSGFLCN--DRGRCSMGQCVCEPGWTGPSCDCPLS 578
+ G+ Y GQ+CE D C R +G +C RG C G+C C PG+ G +C C +
Sbjct: 520 HTSDVPGKLIY-GQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERT 578
Query: 579 NATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAW 638
C++ C+GRG C C C CH S Y +C+ P C SC +C +
Sbjct: 579 TEGCLNPRRVECSGRGRCRCNVCECH--SGYQLPLCQECPGC--PSPCGKYISCAECLKF 634
Query: 639 GTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTME-GDGAPGPNST 697
G G+ C +++ + + C RD + C +YT+E DG
Sbjct: 635 EKG-PFGKNCSAACPGLQLSNNPVKGR----TCKERD-SEGCWVAYTLEQQDGM--DRYL 686
Query: 698 VLVHKKKDCPPG-SFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVG 756
+ V + ++C G + ++ + + L+ +LLL+ WK AL+ H+
Sbjct: 687 IYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWK---------ALI------HLSD 731
Query: 757 FKEDHYMLRENLMASDHLDTPMLRS 781
+E +E L + + D P+ +S
Sbjct: 732 LREYRRFEKEKLKSQWNNDNPLFKS 756
>gi|89191865 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 394 bits (1012), Expect = e-109
Identities = 273/805 (33%), Positives = 399/805 (49%), Gaps = 73/805 (9%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR- 59
M G RP LLA + +SL L+ C K V SC EC+ C +C F
Sbjct: 1 MLGLRPP-----LLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPG 55
Query: 60 -----RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGE 114
RC+T+ +LL GC + I+ S ETQ D + Q+SPQ + + LRPG+
Sbjct: 56 DPDSIRCDTRPQLLMRGCAADDIMDPTS----LAETQEDHNGGQKQLSPQKVTLYLRPGQ 111
Query: 115 ERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKF 174
F + P+DLY LMD S SM DDL N+KK+G +L R L+++T IGFG F
Sbjct: 112 AAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSF 171
Query: 175 VDKVSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLD 230
VDK +P + P+KL+ P PN + PPF+F++V+ LT + ++F+ ++ + ISGNLD
Sbjct: 172 VDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLD 231
Query: 231 APEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHL 290
APEGG DA++Q A C +IGWR + T LLVF+T+ FH+ DG L I++ ND RCHL
Sbjct: 232 APEGGLDAMMQVAACPEEIGWR-NVTRLLVFATDDGFHFAGDGK--LGAILTPNDGRCHL 288
Query: 291 DTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQE 350
+ Y + DYPSV L LA++NI PIFAVT+ YEKL P S++G L E
Sbjct: 289 E-DNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSE 347
Query: 351 DSSNIVELLEEAFNRIRSN--LDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIY 408
DSSN+V+L++ A+N++ S LD AL +VT F + RG+
Sbjct: 348 DSSNVVQLIKNAYNKLSSRVFLDHNALPD----TLKVTYDSFCSNGVTHRNQPRGDCDGV 403
Query: 409 QVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARC 468
Q+ + V T + ++Q I F+D + + C+ C C Q RS C
Sbjct: 404 QINVPITFQVKVT-ATECIQEQSFVIRAL-GFTDIVTVQVLPQCE-CRCRDQSRDRSL-C 459
Query: 469 SFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQ---PCLREGEDKPCSGRGECQCGHCVC 525
G CG C C G+ G+ C C T S + C ++ CSG G+C CG C+C
Sbjct: 460 HGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLC 519
Query: 526 Y-----GEGRYEGQFCEYDNFQCPRTSGFLCN--DRGRCSMGQCVCEPGWTGPSCDCPLS 578
+ G+ Y GQ+CE D C R +G +C RG C G+C C PG+ G +C C +
Sbjct: 520 HTSDVPGKLIY-GQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERT 578
Query: 579 NATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAW 638
C++ C+GRG C C C CH S Y +C+ P C SC +C +
Sbjct: 579 TEGCLNPRRVECSGRGRCRCNVCECH--SGYQLPLCQECPGC--PSPCGKYISCAECLKF 634
Query: 639 GTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTME-GDGAPGPNST 697
G G+ C +++ + + C RD + C +YT+E DG
Sbjct: 635 EKG-PFGKNCSAACPGLQLSNNPVKGR----TCKERD-SEGCWVAYTLEQQDGM--DRYL 686
Query: 698 VLVHKKKDCPPG-SFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVG 756
+ V + ++C G + ++ + + L+ +LLL+ WK AL+ H+
Sbjct: 687 IYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWK---------ALI------HLSD 731
Query: 757 FKEDHYMLRENLMASDHLDTPMLRS 781
+E +E L + + D P+ +S
Sbjct: 732 LREYRRFEKEKLKSQWNNDNPLFKS 756
>gi|4504777 integrin, beta 7 [Homo sapiens]
Length = 798
Score = 387 bits (995), Expect = e-107
Identities = 230/643 (35%), Positives = 327/643 (50%), Gaps = 48/643 (7%)
Query: 25 TLANRCKKAPVKSCTECVRVDKDCAYCTDEMF------RDRRCNTQAELLAAGCQRESIV 78
++ C+ AP SC +C+ CA+C F RRC + ELLA GC E +
Sbjct: 40 SMLGSCQPAP--SCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPLEELE 97
Query: 79 VMESSFQITEETQIDTTLR---RSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYIL 135
++ ++ + R +Q++PQ +RV LRPGE + ++ PVDLY L
Sbjct: 98 EPRGQQEVLQDQPLSQGARGEGATQLAPQRVRVTLRPGEPQQLQVRFLRAEGYPVDLYYL 157
Query: 136 MDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWP 195
MD S SM DDL+ ++++G L L ++T IGFG FVDK +P P KL+ P P
Sbjct: 158 MDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLRHPCP 217
Query: 196 NS----DPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGW 251
PFSF +V+SLT D F ++ + +SGNLD+PEGGFDAILQ A+C IGW
Sbjct: 218 TRLERCQSPFSFHHVLSLTGDAQAFEREVGRQSVSGNLDSPEGGFDAILQAALCQEQIGW 277
Query: 252 RPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLV 311
R + + LLVF+++ FH DG L GI +D CHLD+ G Y++ DYPSV +
Sbjct: 278 R-NVSRLLVFTSDDTFHTAGDGK--LGGIFMPSDGHCHLDSNGLYSRSTEFDYPSVGQVA 334
Query: 312 RLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLD 371
+ L+ NI PIFAVT+ + Y++L P S++G L EDSSN+V+L+ +A+N + S +
Sbjct: 335 QALSAANIQPIFAVTSAALPVYQELSKLIPKSAVGELSEDSSNVVQLIMDAYNSLSSTVT 394
Query: 372 IRALDSPRGLRTEVTSKM--------FQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHV 423
+ P G+ S+ + R H+R + + V L+A + H+
Sbjct: 395 LEHSSLPPGVHISYESQCEGPEKREGKAEDRGQCNHVRINQTVTFWVSLQATHCLPEPHL 454
Query: 424 CQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCS-FNGDFVCGQCVCS 482
+L FS+ L ++ +CD C C + ++ CS G CG C C+
Sbjct: 455 LRL---------RALGFSEELIVELHTLCD-CNCS-DTQPQAPHCSDGQGHLQCGVCSCA 503
Query: 483 EGWSGQTCNCSTGSLS--DIQPCLR--EGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEY 538
G G+ C CS LS D++ R G CSG+G CQCG C C G+ G CE
Sbjct: 504 PGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQS--SGHLCEC 561
Query: 539 DNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCEC 598
D+ C R G LC GRC G C C TG +C+C +CI GG+C+G G C+C
Sbjct: 562 DDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKC 621
Query: 599 GRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTG 641
RC C Y +C+ P CE R C +C A+ TG
Sbjct: 622 NRCQCLDG--YYGALCDQCPGCKTP--CERHRDCAECGAFRTG 660
>gi|4504779 integrin, beta 8 precursor [Homo sapiens]
Length = 769
Score = 323 bits (827), Expect = 1e-87
Identities = 207/700 (29%), Positives = 338/700 (48%), Gaps = 67/700 (9%)
Query: 3 GPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMF-----R 57
GP WA + + ++ + NRC + SC C+ + +C +C E F R
Sbjct: 22 GPASFLWAAWVFSLVLGLGQGED--NRCASSNAASCARCLALGPECGWCVQEDFISGGSR 79
Query: 58 DRRCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERH 117
RC+ + L++ GC +SI I E +I+T Q++P + ++LRPG E +
Sbjct: 80 SERCDIVSNLISKGCSVDSIEYPSVHVIIPTENEINT-----QVTPGEVSIQLRPGAEAN 134
Query: 118 FELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDK 177
F L+V + PVDLY L+D S SM ++++ L +G +L+R ++ + D+ +GFG +VDK
Sbjct: 135 FMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDK 194
Query: 178 VSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPE 233
P + PE++ + + PP + +V+SLTE++ EF + ++ISGN+D PE
Sbjct: 195 TVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPE 254
Query: 234 GGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTT 293
GGFDA+LQ AVC IGWR ++ LL+ T+ H D + LAGI+ ND CHL
Sbjct: 255 GGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALD--SKLAGIVVPNDGNCHL-KN 311
Query: 294 GTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSS 353
Y + T ++PS+ L L +NI IFAV + +Y+ L P + G ++ ++
Sbjct: 312 NVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAA 371
Query: 354 NIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTR----TGSFHIRRGEVGIYQ 409
N+ L+ EA+ ++ S + ++ + +G+ +T+ +R G ++ + ++
Sbjct: 372 NLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRKPGMEGCRNVTSNDEVLFN 431
Query: 410 VQLRALEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC 468
V + ++ D T K +KP F++ K+ C C CE + + +C
Sbjct: 432 VTV-TMKKCDVT-------GGKNYAIIKPIGFNETAKIHIHRNCS-CQCEDNRGPK-GKC 481
Query: 469 SFNGDFVCGQCV-CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCY- 526
+ F+ +C C E C+ S + C + CSGRG C CG C C+
Sbjct: 482 -VDETFLDSKCFQCDE----NKCHFDEDQFSS-ESCKSHKDQPVCSGRGVCVCGKCSCHK 535
Query: 527 -GEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNAT-CID 584
G+ G++CE D+F CP G LC G C G+C C GW G C CP + A C++
Sbjct: 536 IKLGKVYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVN 595
Query: 585 SNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKK 644
S G +C+GRG C CGRC C R C C T K+
Sbjct: 596 SKGQVCSGRGTCVCGRCECTDPRSIG-------------------RFCEHCPTCYTACKE 636
Query: 645 GRTCEEC----NFKVKMVDELKRAEEVVVRCSFRDEDDDC 680
C +C N ++D+ K + ++ + + D+ +C
Sbjct: 637 NWNCMQCLHPHNLSQAILDQCKTSCALMEQQHYVDQTSEC 676
>gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains)
[Homo sapiens]
Length = 494
Score = 140 bits (352), Expect = 1e-32
Identities = 76/224 (33%), Positives = 107/224 (47%), Gaps = 31/224 (13%)
Query: 453 DVCTCELQKEVRSAR-------CSFNGDFVCGQCVCSEGWSGQTC----NCSTGSLSDIQ 501
D C C+ +++ R+ CS +G CG+C C GW G+ C +C+ + I+
Sbjct: 267 DTCECD-ERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIR 325
Query: 502 PCLREGEDKPCSGRGECQCGHCVCY--GEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSM 559
C + D PCSGRG+C+CG C CY G+ R G+ CE D+ +C G +C G CS
Sbjct: 326 KC-QGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSC 384
Query: 560 GQCVCEPGWTGPSCDCP--------LSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTD 611
G+CVCE GW G C P S C ++G +C+G+G C CG+C C + Y
Sbjct: 385 GRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYIS 444
Query: 612 ---TICEINYSAIHPGLC---EDLRSCVQCQAWGTGEKKGRTCE 649
C+ H GL + SC C+ W G CE
Sbjct: 445 GEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGW--NGNACE 486
Score = 114 bits (286), Expect = 7e-25
Identities = 66/196 (33%), Positives = 85/196 (43%), Gaps = 25/196 (12%)
Query: 452 CDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTC----NCSTGSLSDIQPCLREG 507
C CE + C+ +G CG+C C +GW G C NC Q C +
Sbjct: 91 CHEWVCETYD---GSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMC-KNS 146
Query: 508 EDKPCSGRGECQCGHCVCY---GEGRYEGQFCEYDNFQC-PRTSGFLCNDRGRCSMGQCV 563
+D CS G C CG C C G G G+FCE D+ +C + +C G+C G C
Sbjct: 147 QDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCY 206
Query: 564 CEPGWTGPSCD--CPL----SNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEIN 617
C+ GW G C+ C + S C +G IC+ RG C CG C CH D
Sbjct: 207 CKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGD------ 260
Query: 618 YSAIHPGLCE-DLRSC 632
+ IH CE D R C
Sbjct: 261 WGDIHGDTCECDERDC 276
Score = 108 bits (271), Expect = 4e-23
Identities = 74/232 (31%), Positives = 94/232 (40%), Gaps = 31/232 (13%)
Query: 441 SDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTC--NCSTGSLS 498
SDG + G C+ E + C +G CG C C GW G C C
Sbjct: 167 SDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWE 226
Query: 499 DIQPCLREGEDKPCSGRGECQCGHCVCYGE------GRYEGQFCEYDNFQC----PRTSG 548
+ C + K CS RG C CG C C+ G G CE D C R S
Sbjct: 227 SKRRC-TSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSD 285
Query: 549 FLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNA--------TCIDSNGGICNGRGHCECGR 600
C+ G+C+ G+C C+ GW G C+ P S C S+ C+GRG CECG+
Sbjct: 286 DFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGK 345
Query: 601 CHCH---QQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCE 649
C C+ + +Y T CE + CEDL V C GT CE
Sbjct: 346 CTCYPPGDRRVYGKT-CECD-----DRRCEDLDGVV-CGGHGTCSCGRCVCE 390
Score = 90.9 bits (224), Expect = 1e-17
Identities = 45/132 (34%), Positives = 57/132 (43%), Gaps = 15/132 (11%)
Query: 485 WSGQTCNCSTGSLSDIQPCLREGEDKP---CSGRGECQCGHCVCY--GEGRYEGQFCEYD 539
W G C S + C G+ C GRG C CG C+C+ G + G CE
Sbjct: 35 WPGAACRLSRAESE--RRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECH 92
Query: 540 NFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL--------SNATCIDSNGGICN 591
+ C G C G+C G+C C+ GW G +C P SN C +S IC+
Sbjct: 93 EWVCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICS 152
Query: 592 GRGHCECGRCHC 603
G C CGRC C
Sbjct: 153 NAGTCHCGRCKC 164
Score = 59.7 bits (143), Expect = 3e-08
Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 550 LCNDRGRCSMGQCVC---EPG-WTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQ 605
LC+ RGRC G C+C EPG + GP C+C C +G C G G C+CG+C C Q
Sbjct: 62 LCHGRGRCDCGVCICHVTEPGMFFGPLCEC--HEWVCETYDGSTCAGHGKCDCGKCKCDQ 119
Score = 35.4 bits (80), Expect = 0.51
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGS 496
C+ NG CG C C +GW+G C GS
Sbjct: 463 CTGNGICSCGNCECWDGWNGNACEIWLGS 491
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 97.4 bits (241), Expect = 1e-19
Identities = 67/208 (32%), Positives = 98/208 (47%), Gaps = 17/208 (8%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAH---LLDSKVPS 1180
APQN + ++ W PP +G GY++ YW + DS++E +L P
Sbjct: 1704 APQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYW-EADSQNETEKMKVLFLPEPV 1762
Query: 1181 VELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
V L NL + Y + + A+ A G+GP S RTHQ P P LAF+ ++ST +SW
Sbjct: 1763 VRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSW 1822
Query: 1241 AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVL---VDNPKNRMLLIENLRESQPYRYT 1297
EPA NG + Y V Y + P+ + KV+ V R L + +L + Y +
Sbjct: 1823 GEPAAANGILQGYRVVY----EPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFR 1878
Query: 1298 VKARNGAGWGPEREAIINLATQPKRPMS 1325
V+AR +GPE +A I P S
Sbjct: 1879 VQART-ITYGPELQANITAGPAEGSPGS 1905
Score = 74.7 bits (182), Expect = 8e-13
Identities = 54/203 (26%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 1129 APQNPNAKAAGSRKIHFNWLP-----PSGKPMGYRVKYWIQG-DSESEAHLL-DSKVPSV 1181
AP+N +A+A S +I W +G +GY++ + + D E +H++ + S
Sbjct: 1279 APENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSA 1338
Query: 1182 ELTNLYPYCDYEMKVCAYGAQGEG-PYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
L L + YE++V A+ G G P + L+ RT + P P RL F V T ++ W
Sbjct: 1339 LLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVW 1398
Query: 1241 AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
P E NG I Y++ Y L + ++ R +L Y + + A
Sbjct: 1399 QPPEEPNGIILGYQIAYRLASSSPHTFTTVEV----GATVRQFTATDLAPESAYIFRLSA 1454
Query: 1301 RNGAGWGPEREAIINLATQPKRP 1323
+ GWG EA + + +RP
Sbjct: 1455 KTRQGWGEPLEATVITTEKRERP 1477
Score = 72.8 bits (177), Expect = 3e-12
Identities = 132/619 (21%), Positives = 215/619 (34%), Gaps = 130/619 (21%)
Query: 1123 PHGDLGAPQNPNAKAAGSRKIHFNWLPP--SGKPMGYRVKYWIQGDSESEAHL--LDSKV 1178
PH +PN+ + S + +W+ P P+ Y + + +S + HL + ++
Sbjct: 668 PHSPQNLLVSPNS--SHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEM 725
Query: 1179 PSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVS-CRTHQEVPSEPGRLAFNVVSSTVTQ 1237
V ++ L P Y+ +VCA G G YS+ S +E PS P + N+V+S T
Sbjct: 726 TGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPK---NIVASGRTN 782
Query: 1238 LS----WAEPAET--NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRES 1291
S W P ET NG + Y + Y L G ++ + +P+ L+ +L
Sbjct: 783 QSIMVQWQPPPETEHNGVLRGYILRYRLAGLP----GEYQQRNITSPEVNYCLVTDLIIW 838
Query: 1292 QPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSD 1351
Y V A NGAG G A+ Q +P P
Sbjct: 839 TQYEIQVAAYNGAGLGVFSRAVTEYTLQ-----GVPTAP--------------------- 872
Query: 1352 DVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRV 1411
P Q +V+ T + F N +++ A A P V
Sbjct: 873 -----PQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADA---------PEAV 918
Query: 1412 LSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSR 1471
T T+ D++ + H H T L + + TSV
Sbjct: 919 --TVVTIAPDFHGV---HHGHITNLKKFTAYFTSV------------------------- 948
Query: 1472 SRAQMKGFPPSRGPRDSIILAGRPAAPS--WGPDSRLTAGVPDTPTRLVFSALGPTSLRV 1529
+ P GP P+ P W + + P L F+ + TSL+V
Sbjct: 949 ----LCFTTPGDGP---------PSTPQLVWTQEDK-----PGAVGHLSFTEILDTSLKV 990
Query: 1530 SWQEPRCERP-LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQ 1588
SWQEP + + GY + +++ + + N ++ L +Y V A +
Sbjct: 991 SWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTA 1050
Query: 1589 EGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPR 1648
G G TI S V P P AP LV + +SP S L +
Sbjct: 1051 VGTGLVTSS--TISSGVPP--------------DLPGAPSNLVISNISPRSATLQFRPGY 1094
Query: 1649 RPNGDIVGYLVTCEMAQGGGP---ATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTE 1705
I ++V ++ G T + + + L +P L+ Y+F+++
Sbjct: 1095 DGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIV 1154
Query: 1706 GFGPEREGIITIESQDGGP 1724
G P I++ P
Sbjct: 1155 GPSPYSPSSRVIQTLQAPP 1173
Score = 68.9 bits (167), Expect = 4e-11
Identities = 58/208 (27%), Positives = 92/208 (44%), Gaps = 18/208 (8%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPP-----SGKP--MGYRVKYWIQGDSESEAH---LLDSKV 1178
AP + + A + W+P +G P +GYR+KYW + D +S A + D
Sbjct: 1176 APTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYW-RSDLQSSAVAQVVSDRLE 1234
Query: 1179 PSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQ 1237
+ L + +YE+++ A+ A G GP+S +V RT + VPS P ++ VSST
Sbjct: 1235 REFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQIL 1294
Query: 1238 LSWAEPAE--TNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
L+W E NG I Y++ + + D P + +V + L+ LR+ Y
Sbjct: 1295 LTWTSVPEQDQNGLILGYKILFRAKDLDPEP----RSHIVRGNHTQSALLAGLRKFVLYE 1350
Query: 1296 YTVKARNGAGWGPEREAIINLATQPKRP 1323
V A G G +I T+ P
Sbjct: 1351 LQVLAFTRIGNGVPSTPLILERTKDDAP 1378
Score = 61.2 bits (147), Expect = 9e-09
Identities = 59/223 (26%), Positives = 86/223 (38%), Gaps = 28/223 (12%)
Query: 1511 PDTPTRLVFSALGPTSLRVSWQEPRCERP---LQGYSVEYQLLNGGELHRLNIPNPAQT- 1566
P P RLVF + TS+R+ WQ P E P + GY + Y+L + H T
Sbjct: 1378 PGPPVRLVFPEVRLTSVRIVWQPP--EEPNGIILGYQIAYRLASSSP-HTFTTVEVGATV 1434
Query: 1567 -SVVVEDLLPNHSYVFRVRAQSQEGWGREREG-VITIESQVHPQSPLCPLPGSAFTLSTP 1624
DL P +Y+FR+ A++++GWG E VIT E + P P L P
Sbjct: 1435 RQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPR--------ELLVP 1486
Query: 1625 SAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRL 1684
A ++ SL+L W P + Y G + +
Sbjct: 1487 QA-------EVTARSLRLQWV-PGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATAC 1538
Query: 1685 TVPGLSENVPYKFKVQARTTEG---FGPEREGIITIESQDGGP 1724
V L YK +++A G F E E + T++ G P
Sbjct: 1539 VVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEP 1581
Score = 60.8 bits (146), Expect = 1e-08
Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 26/218 (11%)
Query: 1514 PTRLVFSALGPTSLRVSWQEPRCERP---LQGYSVEY-QLLNGGELHRLNIPNPAQTSVV 1569
P + + L + L V+W P E +QGY + Y + + E ++ + + V
Sbjct: 1705 PQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVR 1764
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
+++L + Y+ + A + G G + + P G + P AP
Sbjct: 1765 LKNLTSHTKYLVSISAFNAAGDGPKSD----------------PQQGRTHQ-AAPGAPSF 1807
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCE---MAQGGGPATAFRVDGDSPESRLTV 1686
L F+ ++ +L +SW P NG + GY V E QG V G+ + L V
Sbjct: 1808 LAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNW-QRWLKV 1866
Query: 1687 PGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1724
L++ V Y F+VQART +GPE + IT +G P
Sbjct: 1867 RDLTKGVTYFFRVQARTIT-YGPELQANITAGPAEGSP 1903
Score = 55.8 bits (133), Expect = 4e-07
Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 24/227 (10%)
Query: 1505 RLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP-LQGYSVEYQLL----NGGELHRLN 1559
R P P+ L FS + T+L VSW EP LQGY V Y+ L ++ +
Sbjct: 1796 RTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVE 1855
Query: 1560 IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF 1619
+ Q + V DL +Y FRV+A++ IT ++ P GS
Sbjct: 1856 VRGNWQRWLKVRDLTKGVTYFFRVQART-----------ITYGPELQANITAGPAEGS-- 1902
Query: 1620 TLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMA-QGGGPATAFRVDGD 1678
P +P ++ T S L L W + GY++ + +G +
Sbjct: 1903 ----PGSPRDVLVTK-SASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRS 1957
Query: 1679 SPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPF 1725
+ L++ L + V Y+F+V A G+G + +Q PF
Sbjct: 1958 ATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 2004
Score = 52.4 bits (124), Expect = 4e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 1113 TSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQG-- 1165
TS+++ + PP P+N A ++ I W PP +G GY ++Y + G
Sbjct: 758 TSRLMLPEEPPSAP---PKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLP 814
Query: 1166 DSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR 1225
+ ++ +V +T+L + YE++V AY G G +S V+ T Q VP+ P +
Sbjct: 815 GEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQ 874
Query: 1226 -LAFNVVSSTVTQLSWAEPAE 1245
+ V+ST Q W P +
Sbjct: 875 NVQTEAVNSTTIQFLWNPPPQ 895
Score = 52.4 bits (124), Expect = 4e-06
Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 1626 APGP---LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPES 1682
APGP LVF + S+++ W+ P PNG I+GY + +A P T V+ +
Sbjct: 1377 APGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLA-SSSPHTFTTVEVGATVR 1435
Query: 1683 RLTVPGLSENVPYKFKVQARTTEGFG-PEREGIITIESQD 1721
+ T L+ Y F++ A+T +G+G P +IT E ++
Sbjct: 1436 QFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRE 1475
Score = 51.2 bits (121), Expect = 9e-06
Identities = 50/214 (23%), Positives = 87/214 (40%), Gaps = 36/214 (16%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYW---IQGDSESEAHLLDSKVP-- 1179
P + +A + + W PP +G GYR+ Y + S +EA L + +
Sbjct: 1582 PGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALH 1641
Query: 1180 -------------------SVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP 1220
ELT+L Y YE+ + AY GE P S+ V + P
Sbjct: 1642 AELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAP 1701
Query: 1221 S-EPGRLAFNVVSSTVTQLSW--AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDN 1277
+ P + ++++ +++W P NG I Y++ Y + N MK + +
Sbjct: 1702 AMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNE-TEKMKVLFLPE 1760
Query: 1278 PKNRMLLIENLRESQPYRYTVKARNGAGWGPERE 1311
P ++ ++NL Y ++ A N AG GP+ +
Sbjct: 1761 P---VVRLKNLTSHTKYLVSISAFNAAGDGPKSD 1791
Score = 45.4 bits (106), Expect = 5e-04
Identities = 60/233 (25%), Positives = 86/233 (36%), Gaps = 27/233 (11%)
Query: 1113 TSQMLSSQPPPHGDL-GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQ------- 1164
TS +SS PP DL GAP N R + P G + WI
Sbjct: 1057 TSSTISSGVPP--DLPGAPSNLVISNISPRSATLQFRP--GYDGKTSISRWIVEGQVGAI 1112
Query: 1165 GDSESEAHLLDSK----VPSVELTNLYPYCDYEMKVCAYGAQGEGPYS-SLVSCRTHQEV 1219
GD E L + + +E+ NL PY Y ++ G PYS S +T Q
Sbjct: 1113 GDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAP 1172
Query: 1220 PS-EPGRLAFNVVSSTVTQLSWAEPAET----NGEITAYEVCYGLVNDDNRPIGPMKKVL 1274
P P + S T +L W ++ N E Y + Y + + + +
Sbjct: 1173 PDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQ----V 1228
Query: 1275 VDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
V + R IE L E Y ++A N G GP E ++ T+ P + P
Sbjct: 1229 VSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSE-VVRGRTRESVPSAAP 1280
Score = 45.1 bits (105), Expect = 6e-04
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 21/222 (9%)
Query: 1509 GVPDTPTRLVFS-ALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTS 1567
GVP P + V + A+ T+++ W P ++ + G + Y+LL P A +
Sbjct: 867 GVPTAPPQNVQTEAVNSTTIQFLWNPPP-QQFINGINQGYKLLAW--------PADAPEA 917
Query: 1568 VVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLST-PSA 1626
V V + P+ V + + + V+ + P P +T P A
Sbjct: 918 VTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTT---PGDGPPSTPQLVWTQEDKPGA 974
Query: 1627 PGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTV 1686
G L FT + SL++SW+ P NG I GY ++ E+ ++ + E + +
Sbjct: 975 VGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYK--I 1032
Query: 1687 PGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL 1728
GLS Y V A T G G++T + G P L
Sbjct: 1033 QGLSSLTTYTIDVAAVTAVG-----TGLVTSSTISSGVPPDL 1069
Score = 31.6 bits (70), Expect = 7.3
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 1621 LSTPSAPGPLVFTALSPDS--LQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGD 1678
+ P +P L+ + S S + LSW RP N I+ Y+V E+++ P +
Sbjct: 665 IELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIV--ELSENNSPWKVHLSNVG 722
Query: 1679 SPESRLTVPGLSENVPYKFKVQARTTEGFG 1708
+ +TV GL+ Y+F+V A G G
Sbjct: 723 PEMTGVTVSGLTPARTYQFRVCAVNEVGRG 752
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 97.1 bits (240), Expect = 1e-19
Identities = 72/209 (34%), Positives = 87/209 (41%), Gaps = 54/209 (25%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C G V G+CVC G++G+ C+ T C R+ C GRG C+ G C+C
Sbjct: 346 CGEGGRCVDGRCVCWPGYTGEDCSTRT--------CPRD-----CRGRGRCEDGECIC-- 390
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCD---CP-------- 576
+ Y G C + CP CN RGRC G+CVC PG+TG C CP
Sbjct: 391 DTGYSGDDCGVRS--CPGD----CNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGR 444
Query: 577 LSNATCIDSNG------------GICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPG 624
N C+ + G G C GRG CE GRC C YT C + PG
Sbjct: 445 CENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPG--YTGRDCG---TRACPG 499
Query: 625 LCEDLRSCVQ----CQAWGTGEKKG-RTC 648
C CV C TGE G R C
Sbjct: 500 DCRGRGRCVDGRCVCNPGFTGEDCGSRRC 528
Score = 89.4 bits (220), Expect = 3e-17
Identities = 69/200 (34%), Positives = 89/200 (44%), Gaps = 44/200 (22%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C+ G V G+CVC G++G +C + C + C GRG C G CVC
Sbjct: 191 CNDQGRCVRGRCVCFPGYTGPSCGWPS--------CPGD-----CQGRGRCVQGVCVC-- 235
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584
+ G C + CPR C+ RGRC G+CVC+PG+TG C CP
Sbjct: 236 RAGFSGPDCSQRS--CPRG----CSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG------ 283
Query: 585 SNGGICNGRGHCECGRCHCHQQSLYTDTICEIN---YSAIHPGLCEDLRSCVQCQAWGTG 641
C+ RG CE GRC C+ YT C + G C+D R CV C TG
Sbjct: 284 -----CSQRGRCENGRCVCNPG--YTGEDCGVRSCPRGCSQRGRCKDGR-CV-CDPGYTG 334
Query: 642 EKKG-RTCE-ECNFKVKMVD 659
E G R+C +C + VD
Sbjct: 335 EDCGTRSCPWDCGEGGRCVD 354
Score = 89.4 bits (220), Expect = 3e-17
Identities = 56/164 (34%), Positives = 75/164 (45%), Gaps = 31/164 (18%)
Query: 443 GLKMDAGIICDVCTCELQKEVRSAR--CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDI 500
GL D +CD RS C G + G+CVC +G+SG+ C +
Sbjct: 536 GLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCG--------V 587
Query: 501 QPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG 560
+ C + CS G CQ G C+C+ EG Y + C CP C+ RGRC G
Sbjct: 588 RQCPND-----CSQHGVCQDGVCICW-EG-YVSEDCSIRT--CPSN----CHGRGRCEEG 634
Query: 561 QCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCH 604
+C+C+PG+TGP+C + A C GRG C G C CH
Sbjct: 635 RCLCDPGYTGPTCATRMCPAD--------CRGRGRCVQGVCLCH 670
Score = 87.4 bits (215), Expect = 1e-16
Identities = 70/200 (35%), Positives = 87/200 (43%), Gaps = 35/200 (17%)
Query: 460 QKEVRSARCSFNGDFVCGQCVCS--EGWSGQTCNCST-GSLSDIQPCLREGE-DKPCSGR 515
Q +VR+ CS +G F +C CS GW G TC+ T + P G C+ +
Sbjct: 136 QTDVRTL-CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQ 194
Query: 516 GECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC-- 573
G C G CVC+ Y G C + + CP C RGRC G CVC G++GP C
Sbjct: 195 GRCVRGRCVCF--PGYTGPSCGWPS--CPGD----CQGRGRCVQGVCVCRAGFSGPDCSQ 246
Query: 574 -DCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEIN---YSAIHPGLCEDL 629
CP C+ RG CE GRC C YT C + G CE+
Sbjct: 247 RSCPRG-----------CSQRGRCEGGRCVCDPG--YTGDDCGMRSCPRGCSQRGRCENG 293
Query: 630 RSCVQCQAWGTGEKKG-RTC 648
R CV C TGE G R+C
Sbjct: 294 R-CV-CNPGYTGEDCGVRSC 311
Score = 71.2 bits (173), Expect = 8e-12
Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 35/184 (19%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C G G+C+C G++G+ C + C + C GRG C G CVC
Sbjct: 470 CRGRGRCESGRCMCWPGYTGRDCGT--------RACPGD-----CRGRGRCVDGRCVC-- 514
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
+ G+ C + +CP C G C G CVC+ G++G C S +C
Sbjct: 515 NPGFTGEDC--GSRRCPGD----CRGHGLCEDGVCVCDAGYSGEDC----STRSC----P 560
Query: 588 GICNGRGHCECGRCHCHQQSLYTDTICEINY---SAIHPGLCEDLRSCVQCQAWGTGEKK 644
G C GRG C GRC C + Y+ C + G+C+D C+ + + + +
Sbjct: 561 GGCRGRGQCLDGRCVC--EDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVSEDCS 617
Query: 645 GRTC 648
RTC
Sbjct: 618 IRTC 621
Score = 70.9 bits (172), Expect = 1e-11
Identities = 47/152 (30%), Positives = 61/152 (40%), Gaps = 31/152 (20%)
Query: 452 CDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKP 511
C + TC + C G G+C+C G++G TC + C +
Sbjct: 616 CSIRTCP-------SNCHGRGRCEEGRCLCDPGYTGPTCAT--------RMCPAD----- 655
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C GRG C G C+C+ Y G+ C + G C R C GQCVC G+ GP
Sbjct: 656 CRGRGRCVQGVCLCHVG--YGGEDCGQEEPPASACPGG-CGPRELCRAGQCVCVEGFRGP 712
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603
C I + G C GRG C G C C
Sbjct: 713 DC--------AIQTCPGDCRGRGECHDGSCVC 736
Score = 68.9 bits (167), Expect = 4e-11
Identities = 146/654 (22%), Positives = 229/654 (35%), Gaps = 96/654 (14%)
Query: 1088 FGAHLGQ---PHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIH 1144
+G H GQ P S + DE + + ++ +PP LG A +
Sbjct: 3019 YGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLG---ELTVTDATPDSLS 3075
Query: 1145 FNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY-GAQG 1203
+W+ P G+ + V+Y GD + +A + V ++ L P Y+M + + G Q
Sbjct: 3076 LSWMVPEGQFDHFLVQYR-NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 3134
Query: 1204 EGPYSSLVSCRTHQEVPSEP-------------GRLAFNVVSSTVTQLSWAEPAETNGEI 1250
GP S++ P+EP G L S LSW P G
Sbjct: 3135 VGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVP---QGRF 3191
Query: 1251 TAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR-YTVKARNGAGWGPE 1309
++ V Y + D +P +V+ + + + L + Y+ + G GP
Sbjct: 3192 DSFTVQYK--DRDGQP-----QVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPV 3244
Query: 1310 REAIINLATQPKRPMSIPIIPDIPIVDAQSGE----------DYDSFLMYSDDVLRSPSG 1359
I P+ P + ++ + S +DSFL+ D P
Sbjct: 3245 STVGITAPLPTPLPVE-PRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQP-- 3301
Query: 1360 SQRPSVSDDTEHLVNGRMD------FAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLS 1413
Q VS D + +D F G N A P P
Sbjct: 3302 -QAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPS-PRLGEL 3359
Query: 1414 TSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSR 1473
T + T D L S T+P V ++ RL + ++
Sbjct: 3360 TVTDATPDSVGL-------SWTVPEGEFDSFVVQ-------YKDKDGRLQVVPVAANQRE 3405
Query: 1474 AQMKGFPPSRGPRDSII-LAGRPAAPSWGPDSR---LTAGVPDTPTRLVFSALGPTSLRV 1529
++G PSR R + L+GR DS L +P L + +SLR+
Sbjct: 3406 VTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRL 3465
Query: 1530 SWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLPNHSYVFRVRAQSQ 1588
SW + P + V+Y+ +G +P A Q +V VEDL P Y F +
Sbjct: 3466 SWTV--AQGPFDSFVVQYRDTDG---QPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLL- 3519
Query: 1589 EGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP-----GPLVFTALSPDSLQLS 1643
G +R G ++ P+ P P P G L T +PDS++LS
Sbjct: 3520 ---GGKRLGPVSALGMTAPEEDT---PAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLS 3573
Query: 1644 WERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKF 1697
W + P V + G A VDGD +S++ + GL + PY+F
Sbjct: 3574 WSVAQGPFDSFV-----VQYEDTNGQPQALLVDGD--QSKILISGLEPSTPYRF 3620
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 32/116 (27%)
Query: 466 ARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKP--------CSGRGE 517
A C G V G C+C G+ G+ C G+++P C R
Sbjct: 654 ADCRGRGRCVQGVCLCHVGYGGEDC----------------GQEEPPASACPGGCGPREL 697
Query: 518 CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC 573
C+ G CVC EG + G C CP C RG C G CVC+ G+ G C
Sbjct: 698 CRAGQCVCV-EG-FRGPDCAIQT--CPGD----CRGRGECHDGSCVCKDGYAGEDC 745
Score = 50.4 bits (119), Expect = 2e-05
Identities = 75/298 (25%), Positives = 114/298 (38%), Gaps = 41/298 (13%)
Query: 1469 GSRSRAQMKGFPPSRGPRDSIILAGRPAAPSWGPDSRLTAGVPDTPTRLVFSALGPTSLR 1528
G+ + G PP P D II G P + P L + SL
Sbjct: 1023 GTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGK---SSGPPRLGELTVTDRTSDSLL 1079
Query: 1529 VSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQ 1588
+ W P E + ++Y+ +G + + + P Q S V+ L P Y F +
Sbjct: 1080 LRWTVPEGE--FDSFVIQYKDRDG-QPQVVPVEGP-QRSAVITSLDPGRKYKFVLYGFV- 1134
Query: 1589 EGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPR 1648
G++R G + E+++ PQS P PG TP G L T +PDSL LSW
Sbjct: 1135 ---GKKRHGPLVAEAKILPQSD--PSPG------TPPHLGNLWVTDPTPDSLHLSW---T 1180
Query: 1649 RPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKV-QARTTEGF 1707
P G ++V + G V+G PE V L + Y+F + + +
Sbjct: 1181 VPEGQFDTFMV--QYRDRDGRPQVVPVEG--PERSFVVSSLDPDHKYRFTLFGIANKKRY 1236
Query: 1708 GP-EREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYS-------SITTTHTSATEPF 1757
GP +G E ++ P P+ + PL E + S+ + T A PF
Sbjct: 1237 GPLTADGTTAPERKEEPPRPE------FLEQPLLGELTVTGVTPDSLRLSWTVAQGPF 1288
Score = 49.3 bits (116), Expect = 3e-05
Identities = 145/638 (22%), Positives = 225/638 (35%), Gaps = 124/638 (19%)
Query: 1140 SRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY 1199
S + +W P G+ + V++ GD + +A + V ++ L P Y+M + +
Sbjct: 2207 SDSLSLSWTVPEGQFDHFLVQFK-NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGF 2265
Query: 1200 -GAQGEGPYSS-----------LVSCRTHQEVPSEPGRLAFNVVSSTVT-----QLSWAE 1242
G Q GP S+ + T P P + ++ T LSW
Sbjct: 2266 HGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTV 2325
Query: 1243 PAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARN 1302
P G+ + V Y N D +P K V ++R+ I L Y+ + +
Sbjct: 2326 P---EGQFDHFLVQYK--NGDGQP----KATRVPGHEDRVT-ISGLEPDNKYKMNLYGFH 2375
Query: 1303 GAGWGPEREAIINLATQPKRP------MSIPIIPDIPIVD--AQSGEDYDSFLM------ 1348
G AI A + + P M P P+ P++ +G DS +
Sbjct: 2376 GGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQ 2435
Query: 1349 --YSDDVLRSPSGSQRPSV----SDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTH 1402
+ ++ RP V +++E V G PG +H YG H
Sbjct: 2436 GRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLE----PGRKYKMH--------LYGLH 2483
Query: 1403 LSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYS-------TLTSVSSHGLPPIW 1455
V V + T ++ T S T P T+T S L W
Sbjct: 2484 EGRRVGP-VSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSW 2542
Query: 1456 EHGRSRL-------------PLSWALGSR-SRAQMKGFPPSRGPRDSIILAGRPAAPSWG 1501
+ R P + +G + S+ ++G P R + + L G G
Sbjct: 2543 TVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGR--KYKMHLYGLHEGRRLG 2600
Query: 1502 P---------DSRLTAGVPD-TPTRLVFSALG--------PTSLRVSWQEPRCERPLQGY 1543
P ++ T VP TP + LG P SL +SW P E +
Sbjct: 2601 PVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVP--EGQFDHF 2658
Query: 1544 SVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI- 1601
V+Y+ NG G+ + +P + V + L P+H Y + G +R G I++
Sbjct: 2659 LVQYR--NGDGQPKAVRVPGH-EDGVTISGLEPDHKYKMNLYGFH----GGQRVGPISVI 2711
Query: 1602 -ESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDSLQLSWERPRRPNGDIVGYL 1658
+ ++P P S P P G L T SPDSL LSW P+ G +
Sbjct: 2712 GVTAAEEETP-SPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ---GHFDSF- 2766
Query: 1659 VTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1696
T + G RV G+ ES +TV GL YK
Sbjct: 2767 -TVQYKDRDGRPQVMRVRGE--ESEVTVGGLEPGRKYK 2801
Score = 48.5 bits (114), Expect = 6e-05
Identities = 64/240 (26%), Positives = 93/240 (38%), Gaps = 30/240 (12%)
Query: 1517 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLP 1575
L + + P SLR+SW + P + V+Y+ G +P + V V L P
Sbjct: 1267 LTVTGVTPDSLRLSWTV--AQGPFDSFMVQYKDAQG---QPQAVPVAGDENEVTVPGLDP 1321
Query: 1576 NHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPG-SAFTLSTPSAP-----GP 1629
+ Y + GR+R G ++ ++ PQ + P + P +P G
Sbjct: 1322 DRKYKMNLYGLR----GRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGE 1377
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1689
L T SPDSL L W P+ G + T + G A RV G ES +TV GL
Sbjct: 1378 LTVTGSSPDSLSLFWTVPQ---GSFDSF--TVQYKDRDGRPRAVRVGG--KESEVTVGGL 1430
Query: 1690 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTT 1749
YK + EG +R G + S G PQ + PL+ +T T
Sbjct: 1431 EPGHKYKMHLYG-LHEG---QRVGPV---SAVGVTAPQQEETPPATESPLEPRLGELTVT 1483
Score = 46.6 bits (109), Expect = 2e-04
Identities = 53/178 (29%), Positives = 75/178 (42%), Gaps = 22/178 (12%)
Query: 1524 PTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1582
P SL +SW P E + V+Y+ NG G+ + +P + V + L P+H Y
Sbjct: 2855 PDSLSLSWMVP--EGQFDHFLVQYR--NGDGQPKVVRVPGH-EDGVTISGLEPDHKYKMN 2909
Query: 1583 VRAQSQEGWGREREGVITI--ESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPD 1638
+ G +R G I++ + ++P P S P P G L T SPD
Sbjct: 2910 LYGFH----GGQRVGPISVIGVTAAEEETP-APTEPSTEAPEPPEEPLLGELTVTGSSPD 2964
Query: 1639 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1696
SL LSW P+ G + T + G RV G+ ES +TV GL YK
Sbjct: 2965 SLSLSWTIPQ---GRFDSF--TVQYKDRDGRPQVVRVRGE--ESEVTVGGLEPGCKYK 3015
Score = 44.7 bits (104), Expect = 8e-04
Identities = 139/641 (21%), Positives = 228/641 (35%), Gaps = 117/641 (18%)
Query: 1118 SSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSK 1177
SS PP G+L S + W P G+ + ++Y + D + + ++
Sbjct: 1059 SSGPPRLGELTVTDRT------SDSLLLRWTVPEGEFDSFVIQYKDR-DGQPQVVPVEGP 1111
Query: 1178 VPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVS-------CRTHQEVPSEPGRLAFNV 1230
S +T+L P Y K YG G+ + LV+ P G L
Sbjct: 1112 QRSAVITSLDPGRKY--KFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTD 1169
Query: 1231 VSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRE 1290
+ LSW P G+ + V Y + D RP + V V+ P+ R ++ +L
Sbjct: 1170 PTPDSLHLSWTVP---EGQFDTFMVQYR--DRDGRP----QVVPVEGPE-RSFVVSSLDP 1219
Query: 1291 SQPYRYTVKA-RNGAGWGP---EREAIINLATQPKRP--MSIPIIPDIPIVDAQSGE--- 1341
YR+T+ N +GP + +P RP + P++ ++ +
Sbjct: 1220 DHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRL 1279
Query: 1342 -------DYDSFLMYSDDVLRSP-----SGSQR----PSVSDDTEHLVN--GRMDFAFPG 1383
+DSF++ D P +G + P + D ++ +N G G
Sbjct: 1280 SWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVG 1339
Query: 1384 STNSLHRMT-------TTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTL 1436
+ + + T S GT +P P L T+T + S T+
Sbjct: 1340 PESVVAKTAPQEDVDETPSPTELGTE-APESPEEPLLGELTVTGS----SPDSLSLFWTV 1394
Query: 1437 PR---DYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAG 1493
P+ D T+ G P G G S + G P G + + L G
Sbjct: 1395 PQGSFDSFTVQYKDRDGRPRAVRVG----------GKESEVTVGGLEP--GHKYKMHLYG 1442
Query: 1494 RPAAPSWGPDSRLTAGVP---DTPT-----------RLVFSALGPTSLRVSWQEPRCERP 1539
GP S + P +TP L + + P S+ +SW P E
Sbjct: 1443 LHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVP--EGQ 1500
Query: 1540 LQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGV 1598
+ V+Y+ +G +P A Q V V +L P Y + +R G
Sbjct: 1501 FDSFIVQYKDKDG---QPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDG----QRMGP 1553
Query: 1599 ITIESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDSLQLSWERPRRPNGDIVG 1656
+++ V +PL P P + + P P G L T ++PDS+ LSW P G+
Sbjct: 1554 LSV---VIVTAPLPPAPATEAS-KPPLEPRLGELTVTDITPDSVGLSW---TVPEGEFDS 1606
Query: 1657 YLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKF 1697
++V + G D + +T+P L + YKF
Sbjct: 1607 FVVQYKDRDGQPQVVPVAAD----QREVTIPDLEPSRKYKF 1643
Score = 44.3 bits (103), Expect = 0.001
Identities = 52/181 (28%), Positives = 72/181 (39%), Gaps = 28/181 (15%)
Query: 1524 PTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1582
P SL +SW P E + V+Y+ NG G+ + +P + V + L P+H Y
Sbjct: 2000 PDSLSLSWTVP--EGQFDHFLVQYR--NGDGQPKAVRVPGHEE-GVTISGLEPDHKYKMN 2054
Query: 1583 VRAQSQEGWGREREGVITI-------ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTAL 1635
+ G +R G +++ E P P P A G L T
Sbjct: 2055 LYGFH----GGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPA----EEPLLGELTVTGS 2106
Query: 1636 SPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPY 1695
SPDSL LSW P+ G + T + G RV G+ ES +TV GL Y
Sbjct: 2107 SPDSLSLSWTVPQ---GRFDSF--TVQYKDRDGRPQVVRVGGE--ESEVTVGGLEPGRKY 2159
Query: 1696 K 1696
K
Sbjct: 2160 K 2160
Score = 43.9 bits (102), Expect = 0.001
Identities = 139/652 (21%), Positives = 223/652 (34%), Gaps = 127/652 (19%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSV 1181
PP LG + + +W P G+ + V+Y + D + + ++ + V
Sbjct: 1773 PPKPRLG--EELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDR-DGQPQVVPVEGSLREV 1829
Query: 1182 ELTNLYPYCDYEMKVCAYG---AQGEGPYSSLVSCRTHQEVPSEP------------GRL 1226
+ L P Y K+ YG + GP S++ +E +E G L
Sbjct: 1830 SVPGLDPAHRY--KLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGEL 1887
Query: 1227 AFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIE 1286
+S LSW T GE ++E+ Y D + G ++ V + +N + L
Sbjct: 1888 TVEEATSHTLHLSWMV---TEGEFDSFEIQY---TDRD---GQLQMVRIGGDRNDITL-S 1937
Query: 1287 NLRESQPYRYTVKA-RNGAGWGP---------EREAIINLATQPKRPMSIPIIPDIPIVD 1336
L Y T+ +G GP E E T P P + ++ + D
Sbjct: 1938 GLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTD 1997
Query: 1337 AQSGE----------DYDSFLMY------SDDVLRSPSGSQRPSVSD-DTEHLVNGRMDF 1379
A +D FL+ +R P + ++S + +H + +
Sbjct: 1998 ATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNL-Y 2056
Query: 1380 AFPGSTNSLHRMTTTSAAAYGTHLSPHVPHR---------VLSTSSTLTRDYNSLTRSEH 1430
F G AA SP P +L + +SL
Sbjct: 2057 GFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSL----- 2111
Query: 1431 SHSTTLPR---DYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRD 1487
S S T+P+ D T+ G P + G G S + G P R +
Sbjct: 2112 SLSWTVPQGRFDSFTVQYKDRDGRPQVVRVG----------GEESEVTVGGLEPGR--KY 2159
Query: 1488 SIILAGRPAAPSWGPDSRLTAGVPDTPT-----------RLVFSALGPTSLRVSWQEPRC 1536
+ L G GP S + P+ + ++ + SL +SW P
Sbjct: 2160 KMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVP-- 2217
Query: 1537 ERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGRER 1595
E + V+++ NG G+ + +P + V + L P+H Y + G +R
Sbjct: 2218 EGQFDHFLVQFK--NGDGQPKAVRVPGH-EDGVTISGLEPDHKYKMNLYGFH----GGQR 2270
Query: 1596 EGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP--------LVFTALSPDSLQLSWERP 1647
G ++ P P S + P P P L T +PDSL LSW
Sbjct: 2271 VGPVSAVGLTAPGKDEEMAPAS----TEPPTPEPPIKPRLEELTVTDATPDSLSLSW--- 2323
Query: 1648 RRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKV 1699
P G +LV + G G A RV G E R+T+ GL + YK +
Sbjct: 2324 TVPEGQFDHFLV--QYKNGDGQPKATRVPGH--EDRVTISGLEPDNKYKMNL 2371
Score = 43.5 bits (101), Expect = 0.002
Identities = 39/132 (29%), Positives = 57/132 (43%), Gaps = 14/132 (10%)
Query: 1499 SWG-PDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHR 1557
SWG P S+ + D P L A+ PT+L + W P+ E + + V Y + G + R
Sbjct: 827 SWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAE--VDRFVVSY-VSAGNQRVR 883
Query: 1558 LNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGS 1617
L +P P ++ DL+P YV V A ER ++ + V + PL G
Sbjct: 884 LEVP-PEADGTLLTDLMPGVEYVVTVTA--------ERGRAVSYPASVRANTGSSPL-GL 933
Query: 1618 AFTLSTPSAPGP 1629
T P GP
Sbjct: 934 LGTTDEPPPSGP 945
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 24/160 (15%)
Query: 1491 LAGRPAAPSWGPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLL 1550
L G A S +R + V ++P L FS + TS +V+W P + V YQL
Sbjct: 3734 LRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRA--DSFKVSYQLA 3791
Query: 1551 NGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSP 1610
+GGE + + A+T ++ L+P Y V S G+
Sbjct: 3792 DGGEPQSVQVDGQARTQ-KLQGLIPGARY--EVTVVSVRGFEESE--------------- 3833
Query: 1611 LCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRP 1650
PL G F + P P L L+ L W+ P+ P
Sbjct: 3834 --PLTG--FLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 3869
Score = 41.6 bits (96), Expect = 0.007
Identities = 62/245 (25%), Positives = 97/245 (39%), Gaps = 40/245 (16%)
Query: 1484 GPRDSI-ILAGRPAAPSWGPDSRLTAGVPDTPT----RLVFSALGPTSLRVSWQEPRCER 1538
GP ++ I AGR ++ TA P P L +L +SW E
Sbjct: 1854 GPISAVAITAGREET-----ETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGE- 1907
Query: 1539 PLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGV 1598
+ ++Y +G +L + I + + + L +H Y+ + S + G
Sbjct: 1908 -FDSFEIQYTDRDG-QLQMVRIGGD-RNDITLSGLESDHRYLVTLYGFSDG----KHVGP 1960
Query: 1599 ITIESQVHPQSPLCPLPGSAFTLSTPSAP-----GPLVFTALSPDSLQLSWERPRRPNGD 1653
+ +E+ P+ P +A TP P G L T +PDSL LSW P G
Sbjct: 1961 VHVEALTVPEEEKPSEPPTA----TPEPPIKPRLGELTVTDATPDSLSLSW---TVPEGQ 2013
Query: 1654 IVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGF-GPERE 1712
+LV + G G A RV G E +T+ GL + YK + GF G +R
Sbjct: 2014 FDHFLV--QYRNGDGQPKAVRVPGH--EEGVTISGLEPDHKYKMNLY-----GFHGGQRM 2064
Query: 1713 GIITI 1717
G +++
Sbjct: 2065 GPVSV 2069
Score = 41.2 bits (95), Expect = 0.009
Identities = 62/238 (26%), Positives = 94/238 (39%), Gaps = 30/238 (12%)
Query: 1489 IILAGRPAAPSWGPD-SRLTAGVPDTPTR-----LVFSALGPTSLRVSWQEPRCERPLQG 1542
I + G AA P + L+ P+ P L + P SL +SW P+
Sbjct: 2708 ISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGH--FDS 2765
Query: 1543 YSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIE 1602
++V+Y+ +G ++ ++ V V L P Y + + GR V T+
Sbjct: 2766 FTVQYKDRDGRP--QVMRVRGEESEVTVGGLEPGRKYKMHLYGLHE---GRRVGPVSTVG 2820
Query: 1603 SQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVT 1660
+P + T P+ P G L T +PDSL LSW P G +LV
Sbjct: 2821 VTEDEAETTQAVPTT--TPEPPNKPRLGELTVTDATPDSLSLSW---MVPEGQFDHFLV- 2874
Query: 1661 CEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGF-GPEREGIITI 1717
+ G G RV G E +T+ GL + YK + GF G +R G I++
Sbjct: 2875 -QYRNGDGQPKVVRVPGH--EDGVTISGLEPDHKYKMNLY-----GFHGGQRVGPISV 2924
Score = 40.4 bits (93), Expect = 0.016
Identities = 155/737 (21%), Positives = 256/737 (34%), Gaps = 134/737 (18%)
Query: 1088 FGAHLGQ---PHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIH 1144
+G H G+ P ST + D E ++ + + +PP LG A +
Sbjct: 2805 YGLHEGRRVGPVSTVGVTEDEAETTQAVPTT--TPEPPNKPRLG---ELTVTDATPDSLS 2859
Query: 1145 FNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY-GAQG 1203
+W+ P G+ + V+Y GD + + + V ++ L P Y+M + + G Q
Sbjct: 2860 LSWMVPEGQFDHFLVQYR-NGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2918
Query: 1204 EGPYSSLVSCRTHQEVPS-------------EP--GRLAFNVVSSTVTQLSWAEPAETNG 1248
GP S + +E P+ EP G L S LSW P G
Sbjct: 2919 VGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIP---QG 2975
Query: 1249 EITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR-YTVKARNGAGWG 1307
++ V Y + D RP +V+ + + + L Y+ + G G
Sbjct: 2976 RFDSFTVQYK--DRDGRP-----QVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVG 3028
Query: 1308 P-----------EREAIINLATQPKRPMSIPIIPDIPIVDAQSGE----------DYDSF 1346
P E E + T P P + ++ + DA +D F
Sbjct: 3029 PVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHF 3088
Query: 1347 LMYSDDVLRSPSGSQRPSVSD-------DTEHLVNGRMDFAFPG-------STNSLHRMT 1392
L+ + P + P D + +H + + F G S +
Sbjct: 3089 LVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL-YGFHGGQRVGPVSAIGVTEEE 3147
Query: 1393 TTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPR---DYSTLTSVSSH 1449
T S T +P P L T+T + S S T+P+ D T+
Sbjct: 3148 TPSPTEPSTE-APEAPEEPLLGELTVTGS----SPDSLSLSWTVPQGRFDSFTVQYKDRD 3202
Query: 1450 GLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPSWGPDSR--LT 1507
G P + G S + G P R + + L G GP S +T
Sbjct: 3203 GQPQVVR----------VRGEESEVTVGGLEPGR--KYKMHLYGLHEGQRVGPVSTVGIT 3250
Query: 1508 AGVPDTPT-------RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI 1560
A +P TP L +A+ S+ +SW + P + V+Y+ G + + +
Sbjct: 3251 APLP-TPLPVEPRLGELAVAAVTSDSVGLSWTV--AQGPFDSFLVQYRDAQG-QPQAVPV 3306
Query: 1561 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT 1620
+ +V V L P Y F + Q G +R G + +E++ P + P G
Sbjct: 3307 SGDLR-AVAVSGLDPARKYKFLLFGL-QNG---KRHGPVPVEARTAPDTKPSPRLGE--- 3358
Query: 1621 LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1680
L T +PDS+ LSW P G+ ++V + G +
Sbjct: 3359 ---------LTVTDATPDSVGLSW---TVPEGEFDSFVVQYKDKDGRLQVVPVAAN---- 3402
Query: 1681 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1740
+ +TV GL + Y+F + + G +R G I+ +S +L G +
Sbjct: 3403 QREVTVQGLEPSRKYRFLLYGLS----GRKRLGPISADSTTAPLEKELPPHLGELT-VAE 3457
Query: 1741 SEYSSITTTHTSATEPF 1757
SS+ + T A PF
Sbjct: 3458 ETSSSLRLSWTVAQGPF 3474
Score = 39.3 bits (90), Expect = 0.035
Identities = 59/234 (25%), Positives = 93/234 (39%), Gaps = 39/234 (16%)
Query: 1489 IILAGRPAAPSWGPDSRLTAGVPDTPTRL---VFSALGPTSLRVSWQEPRCERPLQGYSV 1545
I+ A P AP+ A P RL + + P S+ +SW P E + V
Sbjct: 1558 IVTAPLPPAPA------TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGE--FDSFVV 1609
Query: 1546 EYQLLNGGELHRLNIPNPA-QTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQ 1604
+Y+ +G +P A Q V + DL P+ Y F + Q+G +R +++E++
Sbjct: 1610 QYKDRDG---QPQVVPVAADQREVTIPDLEPSRKYKFLLFG-IQDG---KRRSPVSVEAK 1662
Query: 1605 VHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMA 1664
+ P P G L T +PDSL+LSW P G ++V +
Sbjct: 1663 TVARGDASP--------GAPPRLGELWVTDPTPDSLRLSW---TVPEGQFDSFVV--QFK 1709
Query: 1665 QGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIE 1718
GP V + E +TV L Y+F + G +R G +T +
Sbjct: 1710 DKDGPQV---VPVEGHERSVTVTPLDAGRKYRFLLYGL----LGKKRHGPLTAD 1756
Score = 36.2 bits (82), Expect = 0.30
Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Query: 1146 NWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY-GAQGE 1204
NW+PP + ++V Y + E ++ +D + + +L L P YE+ V + G +
Sbjct: 3773 NWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEES 3832
Query: 1205 GPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEP 1243
P + ++ VP P +L ++ L W P
Sbjct: 3833 EPLTGFLT-----TVPDGPTQLRALNLTEGFAVLHWKPP 3866
Score = 35.8 bits (81), Expect = 0.39
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 1127 LGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNL 1186
L AP++ AK R W P +P GY + + G E LL + S +L L
Sbjct: 3931 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEI-LLPGGITSHQLLGL 3989
Query: 1187 YPYCDYEMKVCAYGAQ 1202
+P Y ++ A Q
Sbjct: 3990 FPSTSYNARLQAMWGQ 4005
Score = 33.5 bits (75), Expect = 1.9
Identities = 51/230 (22%), Positives = 79/230 (34%), Gaps = 47/230 (20%)
Query: 1522 LGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVE-DLLPNHSYV 1580
L T++R W P+ Y +++ G P+ S + L P Y
Sbjct: 760 LEETTVRTEWTP--APGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ 817
Query: 1581 FRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSL 1640
VRA WG LP S + P L A++P +L
Sbjct: 818 VTVRALRGTSWG---------------------LPASKTITTMIDGPQDLRVVAVTPTTL 856
Query: 1641 QLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLT--VPGL--------- 1689
+L W RP ++ ++V+ G V ++ + LT +PG+
Sbjct: 857 ELGW---LRPQAEVDRFVVS--YVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAE 911
Query: 1690 -SENVPYKFKVQARTTEGFGPEREGII--TIESQDGGPFPQLGSRAGLFQ 1736
V Y V+A T G G++ T E GP G++A L Q
Sbjct: 912 RGRAVSYPASVRANT----GSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQ 957
Score = 31.6 bits (70), Expect = 7.3
Identities = 46/193 (23%), Positives = 73/193 (37%), Gaps = 24/193 (12%)
Query: 1511 PDTPT--RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1568
P+ P L + P SL + W P + ++V+Y+ +G R ++ V
Sbjct: 1370 PEEPLLGELTVTGSSPDSLSLFWTVP--QGSFDSFTVQYKDRDGRP--RAVRVGGKESEV 1425
Query: 1569 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP- 1627
V L P H Y + EG +R G ++ PQ P P + +P P
Sbjct: 1426 TVGGLEPGHKYKMHLYGL-HEG---QRVGPVSAVGVTAPQQEETP-PAT----ESPLEPR 1476
Query: 1628 -GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTV 1686
G L T ++P+S+ LSW P G ++V + G D + +TV
Sbjct: 1477 LGELTVTDVTPNSVGLSW---TVPEGQFDSFIVQYKDKDGQPQVVPVAAD----QREVTV 1529
Query: 1687 PGLSENVPYKFKV 1699
L YK +
Sbjct: 1530 YNLEPERKYKMNM 1542
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 95.9 bits (237), Expect = 3e-19
Identities = 156/661 (23%), Positives = 243/661 (36%), Gaps = 111/661 (16%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLL-DSKVPSVELTNLY 1187
AP P + I W + P+ Y V + + + D + L
Sbjct: 334 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 393
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAET 1246
P +YE+ V A + G+GP S V RT ++ P S P + ++S+T + W EP E
Sbjct: 394 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 453
Query: 1247 NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
NG I Y V Y + + P+G +K VD+ + + + +L E + Y V A G
Sbjct: 454 NGLIRGYRVYYTM--EPEHPVGNWQKHNVDD--SLLTTVGSLLEDETYTVRVLAFTSVGD 509
Query: 1307 GPEREAIINLATQ---PKRPMSI--PIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQ 1361
GP + I + TQ P +PM++ + I + S +S + Y G +
Sbjct: 510 GPLSDP-IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGRE 568
Query: 1362 RPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRD 1421
D T V + +T R+ S G +P V R L
Sbjct: 569 VGRTFDPTTSYVVEDL----KPNTEYAFRLAARSPQGLGA-FTPVVRQRTL--------- 614
Query: 1422 YNSLTRSEHSHSTTLPRDYSTLTSVSSHGL-----PPIWEHGRSRLPLS---WALGSR-- 1471
S + P+D ++ S+ L PP H + + S LGS
Sbjct: 615 --------QSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDP 666
Query: 1472 SRAQMKGFPPSRGPRDSIILAGRPAAPSW---------------GPDS-----RLTAGVP 1511
++ G PP+ I+L A W GP+S R VP
Sbjct: 667 EPKEVNGIPPT---TTQILL---EALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVP 720
Query: 1512 DTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH----------- 1556
P R V AL T++RV W+ P R ++GY V Y + G E
Sbjct: 721 SAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLA 780
Query: 1557 --RLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWG-REREGVITIESQVHPQSPLCP 1613
+ + A+ +V+ +L P +Y V A + +G G R + V+ + V +
Sbjct: 781 DAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---- 836
Query: 1614 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGD-IVGYLVTCEMAQGGGPATA 1672
TLS P SL WE P D ++GY + AT
Sbjct: 837 ------TLSVQQTP---------EGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLAT- 880
Query: 1673 FRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1732
++ E R T G+ + Y F++ AR+ G G E +++I PQ+ A
Sbjct: 881 --LEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAA 938
Query: 1733 G 1733
G
Sbjct: 939 G 939
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/194 (30%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWI---QGDSESEAHLLDSKVPSVELT 1184
G P N A+A I +W PP + + +KY + +GD E S +
Sbjct: 526 GQPMNLRAEARSETSITLSWSPPRQESI---IKYELLFREGDHGREVGRTFDPTTSYVVE 582
Query: 1185 NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAEP 1243
+L P +Y ++ A QG G ++ +V RT Q PS P + V V ST +SW P
Sbjct: 583 DLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPP 642
Query: 1244 A-ET-NGEITAYEVCYG-LVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
ET NG + Y V Y L ++D P K+V P +L+E L + YR T A
Sbjct: 643 PPETHNGALVGYSVRYRPLGSEDPEP----KEVNGIPPTTTQILLEALEKWTQYRITTVA 698
Query: 1301 RNGAGWGPEREAII 1314
G GPE ++
Sbjct: 699 HTEVGPGPESSPVV 712
Score = 53.9 bits (128), Expect = 1e-06
Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1510 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1569
+P P + + TS+ ++W + P+ Y +EY+ + +++ + T
Sbjct: 331 LPKAPGTPMVTENTATSITITWDSGNPD-PVSYYVIEYKSKSQDGPYQIK-EDITTTRYS 388
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
+ L PN Y V A + G G E V+T + P S AP
Sbjct: 389 IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPAS----------------APRN 432
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1687
+ LS ++ + WE P PNG I GY V T E G VD +S LT
Sbjct: 433 VQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD----DSLLTTV 488
Query: 1688 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1732
G L E+ Y +V A T+ G GP + I +++Q G P + RA
Sbjct: 489 GSLLEDETYTVRVLAFTSVGDGPLSDP-IQVKTQQGVPGQPMNLRA 533
Score = 43.5 bits (101), Expect = 0.002
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 1622 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGY-LVTCEMAQGGGPATAFRVDGDSP 1680
S P APG + T + S+ ++W+ N D V Y ++ + GP +++ D
Sbjct: 330 SLPKAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEYKSKSQDGP---YQIKEDIT 383
Query: 1681 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1740
+R ++ GLS N Y+ V A + G GP E ++T + G P R +Q
Sbjct: 384 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVT---RTGEQAPASAPR------NVQ 434
Query: 1741 SEYSSITTTHTSATEPFLVDGLTLG 1765
+ S TT EP +GL G
Sbjct: 435 ARMLSATTMIVQWEEPVEPNGLIRG 459
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/186 (25%), Positives = 68/186 (36%), Gaps = 15/186 (8%)
Query: 1089 GAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWL 1148
G H G + + R L + + P G + +AG+ + WL
Sbjct: 894 GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGT--VLLRWL 951
Query: 1149 PP-SGKPMGYRVKYWIQGDSES------EAHLLDSKVPSVE----LTNLYPYCDYEMKVC 1197
PP + G VKY + E L + P E L L P Y+++V
Sbjct: 952 PPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVR 1011
Query: 1198 AYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCY 1257
A+ +G GP+S V RT P ++ T LSW P N T Y++ Y
Sbjct: 1012 AHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSP-TPYKIQY 1070
Query: 1258 -GLVND 1262
GL D
Sbjct: 1071 NGLTLD 1076
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 95.9 bits (237), Expect = 3e-19
Identities = 156/652 (23%), Positives = 247/652 (37%), Gaps = 109/652 (16%)
Query: 1105 PDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKY 1161
P E R+ T + S PP + A+ + + W PP +G GYRV Y
Sbjct: 400 PSEAVRARTGEQAPSSPP--------RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYY 451
Query: 1162 WIQGDSESEA---HLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
A H D+ + + + +L P Y ++V A+ A G+GP S + +T Q
Sbjct: 452 TPDSRRPPNAWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQG 510
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP++P V S T QLSW P + I YE+ Y D+++ KV D
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLPPQE--RIIMYELVYWAAEDEDQ----QHKVTFDPT 564
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWG------------------PEREAIINLATQP 1320
+ L E+L+ YR+ + AR+ G G P++ +++ +
Sbjct: 565 SSYTL--EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTT 622
Query: 1321 KRPMSIP--------IIPDIPIV-DAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEH 1371
R +P +I + +A GED ++ D + R S + TE+
Sbjct: 623 VRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVV--DGISREHSSWDLVGLEKWTEY 680
Query: 1372 LVNGRMDF-AFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSL--TRS 1428
V R PG +S + T G P V +ST Y L
Sbjct: 681 RVWVRAHTDVGPGPESSPVLVRTDEDVPSG----PPRKVEVEPLNSTAVHVYWKLPVPSK 736
Query: 1429 EHSHSTTLPRDYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDS 1488
+H Y L + GLP I + L + G P S
Sbjct: 737 QHGQIRGYQVTYVRLENGEPRGLPIIQD---------VMLAEAQETTISGLTPE--TTYS 785
Query: 1489 IILAGRPAAPSWGPDSR-------LTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP-- 1539
+ +A A + G +R T VP PT ++ + T+L + W P+ E P
Sbjct: 786 VTVA---AYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTAL-LQWHPPK-ELPGE 840
Query: 1540 LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVI 1599
L GY ++Y + + ++ Q V L +Y+FR+ A+++ G G E E I
Sbjct: 841 LLGYRLQYCRADEARPNTIDFGKDDQ-HFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI 899
Query: 1600 TIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERP--RRPNGDIVGY 1657
LP S F P L T L+ + +L+W+ P NG I+ Y
Sbjct: 900 RTPED---------LP-SGF-------PQNLHVTGLTTSTTELAWDPPVLAERNGRIISY 942
Query: 1658 LVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGP 1709
V + + + ++R T+ GL + Y KV+A T++G GP
Sbjct: 943 TVVFRDIN-----SQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGP 989
Score = 58.9 bits (141), Expect = 4e-08
Identities = 57/215 (26%), Positives = 81/215 (37%), Gaps = 20/215 (9%)
Query: 1510 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1569
+P P LV + TS+ ++W E P+ Y ++Y+ G E + A T
Sbjct: 318 LPKPPIDLVVTETTATSVTLTWDSGNSE-PVTYYGIQYRAA-GTEGPFQEVDGVATTRYS 375
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
+ L P Y FRV A + G G E V + P SP P
Sbjct: 376 IGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP----------------PRR 419
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1689
+ LS ++ + WE P PNG + GY V P A+ TV L
Sbjct: 420 VQARMLSASTMLVQWEPPEEPNGLVRGYRV-YYTPDSRRPPNAWHKHNTDAGLLTTVGSL 478
Query: 1690 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1724
+ Y +V A T G GP I +++Q G P
Sbjct: 479 LPGITYSLRVLAFTAVGDGPP-SPTIQVKTQQGVP 512
Score = 58.9 bits (141), Expect = 4e-08
Identities = 62/241 (25%), Positives = 91/241 (37%), Gaps = 36/241 (14%)
Query: 1501 GPDS-----RLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLN 1551
GP+S R VP P R V L T++ V W+ P + ++GY V Y L
Sbjct: 693 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLE 752
Query: 1552 GGELHRLNIPNPAQTS----VVVEDLLPNHSYVFRVRAQSQEGWG-REREGVITIESQVH 1606
GE L I + + L P +Y V A + +G G R + ++T V
Sbjct: 753 NGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAV- 811
Query: 1607 PQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQG 1666
P P ++ T +L L W P+ G+++GY + A
Sbjct: 812 -----------------PGRPTMMISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRADE 853
Query: 1667 GGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFP 1726
P T +D + TV GL + Y F++ A+ G G E E I FP
Sbjct: 854 ARPNT---IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFP 910
Query: 1727 Q 1727
Q
Sbjct: 911 Q 911
Score = 54.3 bits (129), Expect = 1e-06
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 10/146 (6%)
Query: 1186 LYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPA 1244
L P+ +Y +V A + G GP S V RT ++ PS P R+ ++S++ + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE 438
Query: 1245 ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGA 1304
E NG + Y V Y D RP K D + + +L Y V A
Sbjct: 439 EPNGLVRGYRVYY--TPDSRRPPNAWHKHNTD--AGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 1305 GWGPEREAIINLATQPKRPMSIPIIP 1330
G GP I Q K +P P
Sbjct: 495 GDGPPSPTI-----QVKTQQGVPAQP 515
Score = 53.1 bits (126), Expect = 2e-06
Identities = 65/317 (20%), Positives = 115/317 (36%), Gaps = 39/317 (12%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEA-----HLLDSK 1177
G P+ + S +H W P G+ GY+V Y + E ++ ++
Sbjct: 710 GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAE 769
Query: 1178 VPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQ 1237
++ L P Y + V AY +G+G S T VP P + +T
Sbjct: 770 AQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTAL- 828
Query: 1238 LSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYT 1297
L W P E GE+ Y + Y D+ RP + ++ + L + Y +
Sbjct: 829 LQWHPPKELPGELLGYRLQYCRA-DEARP-----NTIDFGKDDQHFTVTGLHKGTTYIFR 882
Query: 1298 VKARNGAGWGPEREAII------------NLATQPKRPMSIPIIPDIPIVDAQSGEDYDS 1345
+ A+N AG G E E I NL + + D P++ ++G
Sbjct: 883 LAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISY 942
Query: 1346 FLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSP 1405
+++ D S + +++ DT + G P +T + TS + LSP
Sbjct: 943 TVVFRD----INSQQELQNITTDTRFTLTGLK----PDTTYDIKVRAWTSKGS--GPLSP 992
Query: 1406 HVPHRVLSTSSTLTRDY 1422
+ R + +++
Sbjct: 993 SIQSRTMPVEQVFAKNF 1009
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 95.1 bits (235), Expect = 5e-19
Identities = 155/652 (23%), Positives = 241/652 (36%), Gaps = 102/652 (15%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLL-DSKVPSVELTNLY 1187
AP P + I W + P+ Y V + + + D + L
Sbjct: 321 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 380
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAET 1246
P +YE+ V A + G+GP S V RT ++ P S P + ++S+T + W EP E
Sbjct: 381 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 440
Query: 1247 NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
NG I Y V Y + + P+G +K VD+ + + + +L E + Y V A G
Sbjct: 441 NGLIRGYRVYYTM--EPEHPVGNWQKHNVDD--SLLTTVGSLLEDETYTVRVLAFTSVGD 496
Query: 1307 GPEREAIINLATQ---PKRPMSI--PIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQ 1361
GP + I + TQ P +PM++ + I + S +S + Y G +
Sbjct: 497 GPLSDP-IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGRE 555
Query: 1362 RPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRD 1421
D T V + +T R+ S G +P V R L
Sbjct: 556 VGRTFDPTTSYVVEDL----KPNTEYAFRLAARSPQGLGA-FTPVVRQRTL--------- 601
Query: 1422 YNSLTRSEHSHSTTLPRDYSTLTSVSSHGL-----PPIWEHGRSRLPLS---WALGSR-- 1471
S + P+D ++ S+ L PP H + + S LGS
Sbjct: 602 --------QSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDP 653
Query: 1472 SRAQMKGFPPSRGPRDSIILAGRPAAPSW---------------GPDS-----RLTAGVP 1511
++ G PP+ I+L A W GP+S R VP
Sbjct: 654 EPKEVNGIPPT---TTQILL---EALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVP 707
Query: 1512 DTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELHR----LNIPNP 1563
P R V AL T++RV W+ P R ++GY V Y + G E ++
Sbjct: 708 SAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLA 767
Query: 1564 AQTSVVVEDLLPNHSYVFRVRAQSQEGWG-REREGVITIESQVHPQSPLCPLPGSAFTLS 1622
+V+ +L P +Y V A + +G G R + V+ + V + TLS
Sbjct: 768 DAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP----------TLS 817
Query: 1623 TPSAPGPLVFTALSPDSLQLSWERPRRPNGD-IVGYLVTCEMAQGGGPATAFRVDGDSPE 1681
P SL WE P D ++GY + AT ++ E
Sbjct: 818 VQQTP---------EGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLAT---LEFPPSE 865
Query: 1682 SRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAG 1733
R T G+ + Y F++ AR+ G G E +++I PQ+ AG
Sbjct: 866 DRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAG 917
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/194 (30%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWI---QGDSESEAHLLDSKVPSVELT 1184
G P N A+A I +W PP + + +KY + +GD E S +
Sbjct: 513 GQPMNLRAEARSETSITLSWSPPRQESI---IKYELLFREGDHGREVGRTFDPTTSYVVE 569
Query: 1185 NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAEP 1243
+L P +Y ++ A QG G ++ +V RT Q PS P + V V ST +SW P
Sbjct: 570 DLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPP 629
Query: 1244 A-ET-NGEITAYEVCYG-LVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
ET NG + Y V Y L ++D P K+V P +L+E L + YR T A
Sbjct: 630 PPETHNGALVGYSVRYRPLGSEDPEP----KEVNGIPPTTTQILLEALEKWTQYRITTVA 685
Query: 1301 RNGAGWGPEREAII 1314
G GPE ++
Sbjct: 686 HTEVGPGPESSPVV 699
Score = 53.9 bits (128), Expect = 1e-06
Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1510 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1569
+P P + + TS+ ++W + P+ Y +EY+ + +++ + T
Sbjct: 318 LPKAPGTPMVTENTATSITITWDSGNPD-PVSYYVIEYKSKSQDGPYQIK-EDITTTRYS 375
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
+ L PN Y V A + G G E V+T + P S AP
Sbjct: 376 IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPAS----------------APRN 419
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1687
+ LS ++ + WE P PNG I GY V T E G VD +S LT
Sbjct: 420 VQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD----DSLLTTV 475
Query: 1688 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1732
G L E+ Y +V A T+ G GP + I +++Q G P + RA
Sbjct: 476 GSLLEDETYTVRVLAFTSVGDGPLSDP-IQVKTQQGVPGQPMNLRA 520
Score = 43.5 bits (101), Expect = 0.002
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 1622 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGY-LVTCEMAQGGGPATAFRVDGDSP 1680
S P APG + T + S+ ++W+ N D V Y ++ + GP +++ D
Sbjct: 317 SLPKAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEYKSKSQDGP---YQIKEDIT 370
Query: 1681 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1740
+R ++ GLS N Y+ V A + G GP E ++T + G P R +Q
Sbjct: 371 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVT---RTGEQAPASAPR------NVQ 421
Query: 1741 SEYSSITTTHTSATEPFLVDGLTLG 1765
+ S TT EP +GL G
Sbjct: 422 ARMLSATTMIVQWEEPVEPNGLIRG 446
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/186 (25%), Positives = 68/186 (36%), Gaps = 15/186 (8%)
Query: 1089 GAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWL 1148
G H G + + R L + + P G + +AG+ + WL
Sbjct: 872 GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGT--VLLRWL 929
Query: 1149 PP-SGKPMGYRVKYWIQGDSES------EAHLLDSKVPSVE----LTNLYPYCDYEMKVC 1197
PP + G VKY + E L + P E L L P Y+++V
Sbjct: 930 PPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVR 989
Query: 1198 AYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCY 1257
A+ +G GP+S V RT P ++ T LSW P N T Y++ Y
Sbjct: 990 AHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSP-TPYKIQY 1048
Query: 1258 -GLVND 1262
GL D
Sbjct: 1049 NGLTLD 1054
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 94.7 bits (234), Expect = 7e-19
Identities = 155/652 (23%), Positives = 247/652 (37%), Gaps = 100/652 (15%)
Query: 1105 PDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKY 1161
P E R+ T + S PP + A+ + + W PP +G GYRV Y
Sbjct: 400 PSEAVRARTGEQAPSSPP--------RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYY 451
Query: 1162 WIQGDSESEA---HLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
A H D+ + + + +L P Y ++V A+ A G+GP S + +T Q
Sbjct: 452 TPDSRRPPNAWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQG 510
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP++P V S T QLSW P + I YE+ Y D+++ KV D
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLPPQE--RIIMYELVYWAAEDEDQ----QHKVTFDPT 564
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWG------------------PEREAIINLATQP 1320
+ L E+L+ YR+ + AR+ G G P++ +++ +
Sbjct: 565 SSYTL--EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTT 622
Query: 1321 KRPMSIP--------IIPDIPIV-DAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEH 1371
R +P +I + +A GED ++ D + R S + TE+
Sbjct: 623 VRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVV--DGISREHSSWDLVGLEKWTEY 680
Query: 1372 LVNGRMDF-AFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSL--TRS 1428
V R PG +S + T G P V +ST Y L
Sbjct: 681 RVWVRAHTDVGPGPESSPVLVRTDEDVPSG----PPRKVEVEPLNSTAVHVYWKLPVPSK 736
Query: 1429 EHSHSTTLPRDYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDS 1488
+H Y L + GLP I + + + G P S
Sbjct: 737 QHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPE--TTYS 794
Query: 1489 IILAGRPAAPSWGPDSR-------LTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP-- 1539
+ +A A + G +R T VP PT ++ + T+L + W P+ E P
Sbjct: 795 VTVA---AYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTAL-LQWHPPK-ELPGE 849
Query: 1540 LQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVI 1599
L GY ++Y + + ++ Q V L +Y+FR+ A+++ G G E E I
Sbjct: 850 LLGYRLQYCRADEARPNTIDFGKDDQ-HFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI 908
Query: 1600 TIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERP--RRPNGDIVGY 1657
LP S F P L T L+ + +L+W+ P NG I+ Y
Sbjct: 909 RTPED---------LP-SGF-------PQNLHVTGLTTSTTELAWDPPVLAERNGRIISY 951
Query: 1658 LVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGP 1709
V + + + ++R T+ GL + Y KV+A T++G GP
Sbjct: 952 TVVFRDIN-----SQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGP 998
Score = 58.9 bits (141), Expect = 4e-08
Identities = 57/215 (26%), Positives = 81/215 (37%), Gaps = 20/215 (9%)
Query: 1510 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1569
+P P LV + TS+ ++W E P+ Y ++Y+ G E + A T
Sbjct: 318 LPKPPIDLVVTETTATSVTLTWDSGNSE-PVTYYGIQYRAA-GTEGPFQEVDGVATTRYS 375
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
+ L P Y FRV A + G G E V + P SP P
Sbjct: 376 IGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP----------------PRR 419
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1689
+ LS ++ + WE P PNG + GY V P A+ TV L
Sbjct: 420 VQARMLSASTMLVQWEPPEEPNGLVRGYRV-YYTPDSRRPPNAWHKHNTDAGLLTTVGSL 478
Query: 1690 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1724
+ Y +V A T G GP I +++Q G P
Sbjct: 479 LPGITYSLRVLAFTAVGDGPP-SPTIQVKTQQGVP 512
Score = 55.8 bits (133), Expect = 4e-07
Identities = 63/250 (25%), Positives = 93/250 (37%), Gaps = 45/250 (18%)
Query: 1501 GPDS-----RLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLN 1551
GP+S R VP P R V L T++ V W+ P + ++GY V Y L
Sbjct: 693 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLE 752
Query: 1552 GGELHRLNI------------PNPAQT-SVVVEDLLPNHSYVFRVRAQSQEGWG-REREG 1597
GE L I P ++ + L P +Y V A + +G G R +
Sbjct: 753 NGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPK 812
Query: 1598 VITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGY 1657
++T V P P ++ T +L L W P+ G+++GY
Sbjct: 813 IVTTTGAV------------------PGRPTMMISTTAMNTAL-LQWHPPKELPGELLGY 853
Query: 1658 LVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITI 1717
+ A P T +D + TV GL + Y F++ A+ G G E E I
Sbjct: 854 RLQYCRADEARPNT---IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRT 910
Query: 1718 ESQDGGPFPQ 1727
FPQ
Sbjct: 911 PEDLPSGFPQ 920
Score = 54.3 bits (129), Expect = 1e-06
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 10/146 (6%)
Query: 1186 LYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPA 1244
L P+ +Y +V A + G GP S V RT ++ PS P R+ ++S++ + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE 438
Query: 1245 ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGA 1304
E NG + Y V Y D RP K D + + +L Y V A
Sbjct: 439 EPNGLVRGYRVYY--TPDSRRPPNAWHKHNTD--AGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 1305 GWGPEREAIINLATQPKRPMSIPIIP 1330
G GP I Q K +P P
Sbjct: 495 GDGPPSPTI-----QVKTQQGVPAQP 515
Score = 50.4 bits (119), Expect = 2e-05
Identities = 70/326 (21%), Positives = 115/326 (35%), Gaps = 48/326 (14%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYW------------IQGDSESE 1170
G P+ + S +H W P G+ GY+V Y IQ +E
Sbjct: 710 GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAE 769
Query: 1171 AHLLDSKVPSVELT--NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAF 1228
A + E T L P Y + V AY +G+G S T VP P +
Sbjct: 770 AQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMIS 829
Query: 1229 NVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENL 1288
+T L W P E GE+ Y + Y D+ RP + ++ + L
Sbjct: 830 TTAMNTAL-LQWHPPKELPGELLGYRLQYCRA-DEARP-----NTIDFGKDDQHFTVTGL 882
Query: 1289 RESQPYRYTVKARNGAGWGPEREAII------------NLATQPKRPMSIPIIPDIPIVD 1336
+ Y + + A+N AG G E E I NL + + D P++
Sbjct: 883 HKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLA 942
Query: 1337 AQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSA 1396
++G +++ D S + +++ DT + G P +T + TS
Sbjct: 943 ERNGRIISYTVVFRD----INSQQELQNITTDTRFTLTGLK----PDTTYDIKVRAWTSK 994
Query: 1397 AAYGTHLSPHVPHRVLSTSSTLTRDY 1422
+ LSP + R + +++
Sbjct: 995 GS--GPLSPSIQSRTMPVEQVFAKNF 1018
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 92.4 bits (228), Expect = 3e-18
Identities = 153/671 (22%), Positives = 251/671 (37%), Gaps = 99/671 (14%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 326 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 385
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 386 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 445
Query: 1248 GEITAYEVCYGLVNDDNRPIGP-MKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
G+I Y V Y + D + + MK + D +++ I NL + Y V A G
Sbjct: 446 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD---SQITTIGNLVPQKTYSVKVLAFTSIGD 500
Query: 1307 GPEREAIINLATQ---PKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRP 1363
GP + I + TQ P +P++ P + ++ ++ S RS + +
Sbjct: 501 GP-LSSDIQVITQTGVPGQPLNFKAEP-----------ESETSILLSWTPPRSDTIANYE 548
Query: 1364 SVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYN 1423
V D EH R+ PG++ L + S Y L+ P + ++++ ++
Sbjct: 549 LVYKDGEHGEEQRITIE-PGTSYRLQGLKPNS--LYYFRLAARSPQGLGASTAEIS---- 601
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHGL------PPIWEHGRSRLPLSWALGSRSRAQMK 1477
R+ S + P+D S TS SS + PP+ + S + K
Sbjct: 602 --ARTMQSKPSAPPQDIS-CTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDK 658
Query: 1478 GFPPSRGPRDS----------------IILAGRPAAPSWGPDS-----RLTAGVPDTPTR 1516
P D+ + A P GP+S R VP P R
Sbjct: 659 PHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGP--GPESLSVLIRTNEDVPSGPPR 716
Query: 1517 LV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELHRLNIPNPAQTS----V 1568
V A+ TS++VSW+ P + ++GY V Y + GE + + +
Sbjct: 717 KVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDM 776
Query: 1569 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1628
++ L P SY V A + +G G + + + P P
Sbjct: 777 IISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP------------------ 818
Query: 1629 PLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPG 1688
LV ++ + W P G + GY + + P T ++ E T
Sbjct: 819 RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG-RKDMEPLTT--LEFSEKEDHFTATD 875
Query: 1689 LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGL--------FQHPLQ 1740
+ + Y F++ AR GFG E I+I + FPQ G +Q P+
Sbjct: 876 IHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVL 935
Query: 1741 SEYSSITTTHT 1751
+E + I T +T
Sbjct: 936 AERNGIITKYT 946
Score = 68.9 bits (167), Expect = 4e-11
Identities = 59/216 (27%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
G P N A+ I +W PP + + G+ E + S L L
Sbjct: 517 GQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLK 576
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSWAEPA-- 1244
P Y ++ A QG G ++ +S RT Q PS P + ++ SST +SW P
Sbjct: 577 PNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVE 636
Query: 1245 ETNGEITAYEVCYGLVN-DDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNG 1303
+ NG IT Y + Y V+ +D++P ++L L+E L + YR TV A
Sbjct: 637 KQNGIITEYSIKYTAVDGEDDKP----HEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 692
Query: 1304 AGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQS 1339
G GPE +++ + T P P ++ V++ S
Sbjct: 693 VGPGPESLSVL-IRTNEDVPSGPPRKVEVEAVNSTS 727
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 19/229 (8%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 397 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 456
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 457 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 514
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 567
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 568 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP 613
Score = 60.1 bits (144), Expect = 2e-08
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1510 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1569
+P P V + TS+ ++W E P+ Y ++++ N EL++ I A T
Sbjct: 322 LPKPPGTPVVTESTATSITLTWDSGNPE-PVSYYIIQHKPKNSEELYK-EIDGVATTRYS 379
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
V L P Y FRV A + G G E V+T S+ P S AP
Sbjct: 380 VAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSS----------------APRD 423
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1687
+ LS ++ + W+ P PNG I GY V T + Q V +S++T
Sbjct: 424 VQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV----ADSQITTI 479
Query: 1688 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1732
G L Y KV A T+ G GP I I +Q G P L +A
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVI-TQTGVPGQPLNFKA 524
Score = 59.3 bits (142), Expect = 3e-08
Identities = 47/192 (24%), Positives = 77/192 (40%), Gaps = 17/192 (8%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKY--WIQGDSESEAHLLDSKVPS 1180
G P+ +A S + +W P G+ GY+V Y G+ + + L D +
Sbjct: 713 GPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLAD 772
Query: 1181 VE---LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQ 1237
+ ++ L P Y + V AY +G+G S T VP +P RL N
Sbjct: 773 AQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP-RLVINHTQMNTAL 831
Query: 1238 LSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYT 1297
+ W P +T G + Y + +G D P+ L + K ++ + Y +
Sbjct: 832 IQWHPPVDTFGPLQGYRLKFG--RKDMEPL----TTLEFSEKEDHFTATDIHKGASYVFR 885
Query: 1298 VKARNGAGWGPE 1309
+ ARN G+G E
Sbjct: 886 LSARNKVGFGEE 897
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 905 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 964
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 965 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1024
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1025 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1073
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1074 FVLTNRGNSAGG 1085
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 1514 PTRLVFSALGPTSLRVSWQEP-RCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVV 1570
P L TS+++SWQ P ER + Y++ Y+ +N L + PA T++ +
Sbjct: 913 PQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTL 972
Query: 1571 EDLLPNHSYVFRVRAQSQEGWG 1592
L P+ +Y +VRA + +G G
Sbjct: 973 TGLKPDTTYDVKVRAHTSKGPG 994
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 91.7 bits (226), Expect = 6e-18
Identities = 153/680 (22%), Positives = 252/680 (37%), Gaps = 108/680 (15%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 326 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 385
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 386 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 445
Query: 1248 GEITAYEVCYGLVNDDNRPIGP-MKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
G+I Y V Y + D + + MK + D +++ I NL + Y V A G
Sbjct: 446 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD---SQITTIGNLVPQKTYSVKVLAFTSIGD 500
Query: 1307 GPEREAIINLATQ---PKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRP 1363
GP + I + TQ P +P++ P + ++ ++ S RS + +
Sbjct: 501 GP-LSSDIQVITQTGVPGQPLNFKAEP-----------ESETSILLSWTPPRSDTIANYE 548
Query: 1364 SVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYN 1423
V D EH R+ PG++ L + S Y L+ P + ++++ ++
Sbjct: 549 LVYKDGEHGEEQRITIE-PGTSYRLQGLKPNS--LYYFRLAARSPQGLGASTAEIS---- 601
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHGL------PPIWEHGRSRLPLSWALGSRSRAQMK 1477
R+ S + P+D S TS SS + PP+ + S + K
Sbjct: 602 --ARTMQSKPSAPPQDIS-CTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDK 658
Query: 1478 GFPPSRGPRDS----------------IILAGRPAAPSWGPDS-----RLTAGVPDTPTR 1516
P D+ + A P GP+S R VP P R
Sbjct: 659 PHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGP--GPESLSVLIRTNEDVPSGPPR 716
Query: 1517 LV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH-------------RLN 1559
V A+ TS++VSW+ P + ++GY V Y + GE +
Sbjct: 717 KVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWE 776
Query: 1560 IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF 1619
+ + +++ L P SY V A + +G G + + + P P
Sbjct: 777 FDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--------- 827
Query: 1620 TLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDS 1679
LV ++ + W P G + GY + + P T ++
Sbjct: 828 ---------RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG-RKDMEPLTT--LEFSE 875
Query: 1680 PESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGL----- 1734
E T + + Y F++ AR GFG E I+I + FPQ G
Sbjct: 876 KEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSV 935
Query: 1735 ---FQHPLQSEYSSITTTHT 1751
+Q P+ +E + I T +T
Sbjct: 936 QLSWQPPVLAERNGIITKYT 955
Score = 68.9 bits (167), Expect = 4e-11
Identities = 59/216 (27%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
G P N A+ I +W PP + + G+ E + S L L
Sbjct: 517 GQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLK 576
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSWAEPA-- 1244
P Y ++ A QG G ++ +S RT Q PS P + ++ SST +SW P
Sbjct: 577 PNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVE 636
Query: 1245 ETNGEITAYEVCYGLVN-DDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNG 1303
+ NG IT Y + Y V+ +D++P ++L L+E L + YR TV A
Sbjct: 637 KQNGIITEYSIKYTAVDGEDDKP----HEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 692
Query: 1304 AGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQS 1339
G GPE +++ + T P P ++ V++ S
Sbjct: 693 VGPGPESLSVL-IRTNEDVPSGPPRKVEVEAVNSTS 727
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 19/229 (8%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 397 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 456
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 457 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 514
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 567
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 568 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP 613
Score = 60.1 bits (144), Expect = 2e-08
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1510 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1569
+P P V + TS+ ++W E P+ Y ++++ N EL++ I A T
Sbjct: 322 LPKPPGTPVVTESTATSITLTWDSGNPE-PVSYYIIQHKPKNSEELYK-EIDGVATTRYS 379
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
V L P Y FRV A + G G E V+T S+ P S AP
Sbjct: 380 VAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSS----------------APRD 423
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1687
+ LS ++ + W+ P PNG I GY V T + Q V +S++T
Sbjct: 424 VQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV----ADSQITTI 479
Query: 1688 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1732
G L Y KV A T+ G GP I I +Q G P L +A
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVI-TQTGVPGQPLNFKA 524
Score = 55.8 bits (133), Expect = 4e-07
Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 26/201 (12%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKY--WIQGDSESEAHLLDSKVPS 1180
G P+ +A S + +W P G+ GY+V Y G+ + + L D +
Sbjct: 713 GPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLAD 772
Query: 1181 VE------------LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAF 1228
+ ++ L P Y + V AY +G+G S T VP +P RL
Sbjct: 773 AQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP-RLVI 831
Query: 1229 NVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENL 1288
N + W P +T G + Y + +G D P+ L + K ++
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFG--RKDMEPL----TTLEFSEKEDHFTATDI 885
Query: 1289 RESQPYRYTVKARNGAGWGPE 1309
+ Y + + ARN G+G E
Sbjct: 886 HKGASYVFRLSARNKVGFGEE 906
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 914 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 973
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 974 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1033
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1034 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1082
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1083 FVLTNRGNSAGG 1094
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 1514 PTRLVFSALGPTSLRVSWQEP-RCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVV 1570
P L TS+++SWQ P ER + Y++ Y+ +N L + PA T++ +
Sbjct: 922 PQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTL 981
Query: 1571 EDLLPNHSYVFRVRAQSQEGWG 1592
L P+ +Y +VRA + +G G
Sbjct: 982 TGLKPDTTYDVKVRAHTSKGPG 1003
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 91.7 bits (226), Expect = 6e-18
Identities = 153/680 (22%), Positives = 252/680 (37%), Gaps = 108/680 (15%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 313 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 372
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 373 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 432
Query: 1248 GEITAYEVCYGLVNDDNRPIGP-MKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
G+I Y V Y + D + + MK + D +++ I NL + Y V A G
Sbjct: 433 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD---SQITTIGNLVPQKTYSVKVLAFTSIGD 487
Query: 1307 GPEREAIINLATQ---PKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRP 1363
GP + I + TQ P +P++ P + ++ ++ S RS + +
Sbjct: 488 GP-LSSDIQVITQTGVPGQPLNFKAEP-----------ESETSILLSWTPPRSDTIANYE 535
Query: 1364 SVSDDTEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYN 1423
V D EH R+ PG++ L + S Y L+ P + ++++ ++
Sbjct: 536 LVYKDGEHGEEQRITIE-PGTSYRLQGLKPNS--LYYFRLAARSPQGLGASTAEIS---- 588
Query: 1424 SLTRSEHSHSTTLPRDYSTLTSVSSHGL------PPIWEHGRSRLPLSWALGSRSRAQMK 1477
R+ S + P+D S TS SS + PP+ + S + K
Sbjct: 589 --ARTMQSKPSAPPQDIS-CTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDK 645
Query: 1478 GFPPSRGPRDS----------------IILAGRPAAPSWGPDS-----RLTAGVPDTPTR 1516
P D+ + A P GP+S R VP P R
Sbjct: 646 PHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGP--GPESLSVLIRTNEDVPSGPPR 703
Query: 1517 LV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH-------------RLN 1559
V A+ TS++VSW+ P + ++GY V Y + GE +
Sbjct: 704 KVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWE 763
Query: 1560 IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF 1619
+ + +++ L P SY V A + +G G + + + P P
Sbjct: 764 FDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--------- 814
Query: 1620 TLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDS 1679
LV ++ + W P G + GY + + P T ++
Sbjct: 815 ---------RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG-RKDMEPLTT--LEFSE 862
Query: 1680 PESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGL----- 1734
E T + + Y F++ AR GFG E I+I + FPQ G
Sbjct: 863 KEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSV 922
Query: 1735 ---FQHPLQSEYSSITTTHT 1751
+Q P+ +E + I T +T
Sbjct: 923 QLSWQPPVLAERNGIITKYT 942
Score = 68.9 bits (167), Expect = 4e-11
Identities = 59/216 (27%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
G P N A+ I +W PP + + G+ E + S L L
Sbjct: 504 GQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLK 563
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSWAEPA-- 1244
P Y ++ A QG G ++ +S RT Q PS P + ++ SST +SW P
Sbjct: 564 PNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVE 623
Query: 1245 ETNGEITAYEVCYGLVN-DDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNG 1303
+ NG IT Y + Y V+ +D++P ++L L+E L + YR TV A
Sbjct: 624 KQNGIITEYSIKYTAVDGEDDKP----HEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 679
Query: 1304 AGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQS 1339
G GPE +++ + T P P ++ V++ S
Sbjct: 680 VGPGPESLSVL-IRTNEDVPSGPPRKVEVEAVNSTS 714
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 19/229 (8%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 384 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 443
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 444 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 501
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 502 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 554
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 555 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP 600
Score = 60.1 bits (144), Expect = 2e-08
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1510 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1569
+P P V + TS+ ++W E P+ Y ++++ N EL++ I A T
Sbjct: 309 LPKPPGTPVVTESTATSITLTWDSGNPE-PVSYYIIQHKPKNSEELYK-EIDGVATTRYS 366
Query: 1570 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1629
V L P Y FRV A + G G E V+T S+ P S AP
Sbjct: 367 VAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSS----------------APRD 410
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1687
+ LS ++ + W+ P PNG I GY V T + Q V +S++T
Sbjct: 411 VQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV----ADSQITTI 466
Query: 1688 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1732
G L Y KV A T+ G GP I I +Q G P L +A
Sbjct: 467 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVI-TQTGVPGQPLNFKA 511
Score = 55.8 bits (133), Expect = 4e-07
Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 26/201 (12%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKY--WIQGDSESEAHLLDSKVPS 1180
G P+ +A S + +W P G+ GY+V Y G+ + + L D +
Sbjct: 700 GPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLAD 759
Query: 1181 VE------------LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAF 1228
+ ++ L P Y + V AY +G+G S T VP +P RL
Sbjct: 760 AQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP-RLVI 818
Query: 1229 NVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENL 1288
N + W P +T G + Y + +G D P+ L + K ++
Sbjct: 819 NHTQMNTALIQWHPPVDTFGPLQGYRLKFG--RKDMEPL----TTLEFSEKEDHFTATDI 872
Query: 1289 RESQPYRYTVKARNGAGWGPE 1309
+ Y + + ARN G+G E
Sbjct: 873 HKGASYVFRLSARNKVGFGEE 893
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 901 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 960
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 961 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1020
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1021 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1069
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1070 FVLTNRGNSAGG 1081
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 1514 PTRLVFSALGPTSLRVSWQEP-RCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVV 1570
P L TS+++SWQ P ER + Y++ Y+ +N L + PA T++ +
Sbjct: 909 PQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTL 968
Query: 1571 EDLLPNHSYVFRVRAQSQEGWG 1592
L P+ +Y +VRA + +G G
Sbjct: 969 TGLKPDTTYDVKVRAHTSKGPG 990
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 567 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 615
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 616 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 665
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 666 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 716
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 717 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 767
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 589 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 641
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 642 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 690
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 691 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 736
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 737 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 794
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 795 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 536 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 587
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 588 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 638
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 639 CVKGECHCSTGWGGVNCE 656
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 566 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 614
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 615 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 664
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 665 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 715
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 716 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 766
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 588 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 640
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 641 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 689
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 690 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 735
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 736 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 793
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 794 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 839
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 535 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 586
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 587 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 637
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 638 CVKGECHCSTGWGGVNCE 655
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 567 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 615
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 616 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 665
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 666 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 716
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 717 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 767
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 589 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 641
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 642 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 690
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 691 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 736
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 737 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 794
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 795 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 536 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 587
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 588 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 638
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 639 CVKGECHCSTGWGGVNCE 656
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 90.5 bits (223), Expect = 1e-17
Identities = 70/224 (31%), Positives = 93/224 (41%), Gaps = 54/224 (24%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCN-------CSTGSLSDIQPCLRE----GED------- 509
CS +G V GQCVC EG++G+ C+ C + C+ E G D
Sbjct: 412 CSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCP 471
Query: 510 KPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWT 569
C G C G CVC + Y G+ C + QCPR C++RG C GQCVCE G+T
Sbjct: 472 NDCHQHGRCVNGMCVC--DDGYTGEDCR--DRQCPRD----CSNRGLCVDGQCVCEDGFT 523
Query: 570 GPSC---DCP--------LSNATCIDSNGGI------------CNGRGHCECGRCHCHQQ 606
GP C CP N C+ G + C+G+G C G+C CH+
Sbjct: 524 GPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEG 583
Query: 607 SLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEE 650
+T C + P C +L CV + G C E
Sbjct: 584 --FTGLDCGQHSC---PSDCNNLGQCVSGRCICNEGYSGEDCSE 622
Score = 76.3 bits (186), Expect = 3e-13
Identities = 65/202 (32%), Positives = 87/202 (43%), Gaps = 41/202 (20%)
Query: 424 CQLPEDQKGNIHLKPSFSDGLKM-DAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCS 482
C PE GN HL+ DG + D G + C+ + + C+ G V G C+C
Sbjct: 185 CSEPECP-GNCHLRGRCIDGQCICDDGFTGEDCS----QLACPSDCNDQGKCVNGVCICF 239
Query: 483 EGWSGQTCN---CSTGSLSDIQPCLR---------EGED--KP-----CSGRGECQCGHC 523
EG++G C+ C + C+ G+D KP C RG C C
Sbjct: 240 EGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENEC 299
Query: 524 VCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCI 583
VC EG + G+ C CP C DRGRC G C CE G+TG C P TC
Sbjct: 300 VC-DEG-FTGEDCS--ELICPND----CFDRGRCINGTCYCEEGFTGEDCGKP----TCP 347
Query: 584 DSNGGICNGRGHCECGRCHCHQ 605
+ C+ +G CE G+C C +
Sbjct: 348 HA----CHTQGRCEEGQCVCDE 365
Score = 73.6 bits (179), Expect = 2e-12
Identities = 63/235 (26%), Positives = 90/235 (38%), Gaps = 49/235 (20%)
Query: 454 VCTC-------ELQKEVRSARCSF-NGDFVCGQCVCSEGWSGQTCN-------CSTGSLS 498
VC C + +E+ CS +G V G CVC +G++G CN C
Sbjct: 235 VCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRC 294
Query: 499 DIQPCLRE----GED-------KPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTS 547
C+ + GED C RG C G C C E + G+ C CP
Sbjct: 295 VENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYC--EEGFTGEDCGKPT--CPHA- 349
Query: 548 GFLCNDRGRCSMGQCVCEPGWTGPSCD---CPL---SNATCIDSNGGICNGRGHCECGRC 601
C+ +GRC GQCVC+ G+ G C CP + C+D +G +CG
Sbjct: 350 ---CHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGEL 406
Query: 602 HC------HQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEE 650
C H + + +C+ Y+ C LR C + G + CE+
Sbjct: 407 KCPNGCSGHGRCVNGQCVCDEGYTGED---CSQLRCPNDCHSRGRCVEGKCVCEQ 458
Score = 72.0 bits (175), Expect = 5e-12
Identities = 63/217 (29%), Positives = 82/217 (37%), Gaps = 67/217 (30%)
Query: 468 CSFNGDFV---CGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSG----RGECQC 520
CS G+F CG CVC GW G C+ + C G RG C
Sbjct: 161 CSGRGNFSTEGCG-CVCEPGWKGPNCS-----------------EPECPGNCHLRGRCID 202
Query: 521 GHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCD---CPL 577
G C+C + + G+ C CP CND+G+C G C+C G+ G C CP+
Sbjct: 203 GQCIC--DDGFTGEDCS--QLACPSD----CNDQGKCVNGVCICFEGYAGADCSREICPV 254
Query: 578 ----SNATCIDS--------NGGICN---------GRGHCECGRCHCHQQSLYTDTICEI 616
+ TC+D G CN RG C C C + +T C
Sbjct: 255 PCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEG--FTGEDCS- 311
Query: 617 NYSAIHPGLCEDLRSCVQ----CQAWGTGEKKGR-TC 648
I P C D C+ C+ TGE G+ TC
Sbjct: 312 --ELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTC 346
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 1622 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPE 1681
S S P LV T ++ +++ L+W+ R + YLV GG FRV GD +
Sbjct: 621 SEVSPPKDLVVTEVTEETVNLAWDNEMR----VTEYLVVYTPTHEGGLEMQFRVPGD--Q 674
Query: 1682 SRLTVPGLSENVPYKFKVQA 1701
+ + L V Y +V A
Sbjct: 675 TSTIIQELEPGVEYFIRVFA 694
Score = 31.2 bits (69), Expect = 9.5
Identities = 52/220 (23%), Positives = 81/220 (36%), Gaps = 38/220 (17%)
Query: 1512 DTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVE 1571
DTP L S TSL + W+ P + Y + Y L G+ + +P TS V+
Sbjct: 986 DTPKDLQVSETAETSLTLLWKTPLAK--FDRYRLNYSLPT-GQWVGVQLPRNT-TSYVLR 1041
Query: 1572 DLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP--GP 1629
L P G+E ++T E H P + ST AP
Sbjct: 1042 GLEP----------------GQEYNVLLTAEKGRHKSKP------ARVKASTEQAPELEN 1079
Query: 1630 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1689
L T + D L+L+W + +++ + A A V G + +PGL
Sbjct: 1080 LTVTEVGWDGLRLNWTAADQA---YEHFIIQVQEANKVEAARNLTVPGSL--RAVDIPGL 1134
Query: 1690 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLG 1729
PY + +G+ R +++ E+ G P LG
Sbjct: 1135 KAATPYTVSIYG-VIQGY---RTPVLSAEAST-GETPNLG 1169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,761,697
Number of Sequences: 37866
Number of extensions: 4007708
Number of successful extensions: 15867
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 277
Number of HSP's that attempted gapping in prelim test: 10655
Number of HSP's gapped (non-prelim): 3301
length of query: 1805
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1688
effective length of database: 13,817,196
effective search space: 23323426848
effective search space used: 23323426848
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.