Search of human proteins with 5454158

Search of human proteins with 5454158

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5454158 valyl-tRNA synthetase [Homo sapiens]
         (1264 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5454158 valyl-tRNA synthetase [Homo sapiens]                      2586   0.0  
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]    1008   0.0  
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]   193   8e-49
gi|94721239 isoleucine tRNA synthetase [Homo sapiens]                 149   2e-35
gi|94721241 isoleucine tRNA synthetase [Homo sapiens]                 149   2e-35
gi|4503481 eukaryotic translation elongation factor 1 gamma [Hom...   130   1e-29
gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho...    77   1e-13
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    47   2e-04
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    47   2e-04
gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]      45   4e-04
gi|108773810 leucyl-tRNA synthetase [Homo sapiens]                     44   0.001
gi|14043022 methionyl-tRNA synthetase [Homo sapiens]                   43   0.002
gi|4557489 cone-rod homeobox protein [Homo sapiens]                    43   0.002
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     40   0.018
gi|157743252 pecanex-like 3 [Homo sapiens]                             39   0.031
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    38   0.070
gi|5803145 ralA binding protein 1 [Homo sapiens]                       38   0.070
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          38   0.070
gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens]           37   0.12 
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]           37   0.12 
gi|20070228 nucleobindin 1 [Homo sapiens]                              37   0.16 
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ...    36   0.27 
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          36   0.27 
gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens]          36   0.27 
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           35   0.35 
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    35   0.45 
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    35   0.45 
gi|196114999 special AT-rich sequence binding protein 1 [Homo sa...    35   0.45 
gi|4506791 special AT-rich sequence binding protein 1 [Homo sapi...    35   0.45 
gi|150170670 piccolo isoform 2 [Homo sapiens]                          35   0.45 

>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
          Length = 1264

 Score = 2586 bits (6704), Expect = 0.0
 Identities = 1264/1264 (100%), Positives = 1264/1264 (100%)

Query: 1    MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPAL 60
            MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPAL
Sbjct: 1    MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPAL 60

Query: 61   EQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALG 120
            EQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALG
Sbjct: 61   EQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALG 120

Query: 121  LRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPA 180
            LRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPA
Sbjct: 121  LRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPA 180

Query: 181  RRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKK 240
            RRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKK
Sbjct: 181  RRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKK 240

Query: 241  REKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSY 300
            REKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSY
Sbjct: 241  REKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSY 300

Query: 301  SPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAI 360
            SPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAI
Sbjct: 301  SPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAI 360

Query: 361  QDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWK 420
            QDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWK
Sbjct: 361  QDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWK 420

Query: 421  EEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCT 480
            EEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCT
Sbjct: 421  EEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCT 480

Query: 481  LNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIET 540
            LNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIET
Sbjct: 481  LNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIET 540

Query: 541  MLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQND 600
            MLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQND
Sbjct: 541  MLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQND 600

Query: 601  YEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVV 660
            YEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVV
Sbjct: 601  YEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVV 660

Query: 661  PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWC 720
            PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWC
Sbjct: 661  PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWC 720

Query: 721  ISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISL 780
            ISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISL
Sbjct: 721  ISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISL 780

Query: 781  QQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKL 840
            QQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKL
Sbjct: 781  QQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKL 840

Query: 841  TGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVE 900
            TGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVE
Sbjct: 841  TGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVE 900

Query: 901  KAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFA 960
            KAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFA
Sbjct: 901  KAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFA 960

Query: 961  LRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLY 1020
            LRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLY
Sbjct: 961  LRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLY 1020

Query: 1021 ELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMP 1080
            ELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMP
Sbjct: 1021 ELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMP 1080

Query: 1081 QAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVAD 1140
            QAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVAD
Sbjct: 1081 QAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVAD 1140

Query: 1141 EATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARE 1200
            EATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARE
Sbjct: 1141 EATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARE 1200

Query: 1201 LGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALF 1260
            LGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALF
Sbjct: 1201 LGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALF 1260

Query: 1261 QKML 1264
            QKML
Sbjct: 1261 QKML 1264


>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
          Length = 1063

 Score = 1008 bits (2607), Expect = 0.0
 Identities = 524/1059 (49%), Positives = 688/1059 (64%), Gaps = 28/1059 (2%)

Query: 210  YSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEK 269
            +S   P  H    ++       ++  +EAK++    + ++KQ   + +     K P    
Sbjct: 18   HSRGLPRFHSVSTQSEPHGSPISRRNREAKQK----RLREKQATLEAEIAGESKSPAESI 73

Query: 270  REKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVS 329
            +  R   ++ Y++PT PGEKKDVSGP+P +YSPRYVEAAWYPWW ++GFFKPEY      
Sbjct: 74   KAWRPKELVLYEIPTKPGEKKDVSGPLPPAYSPRYVEAAWYPWWVREGFFKPEYQARLPQ 133

Query: 330  AANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQ 389
            A      F MCIPPPNVTGSLH+GHALT AIQD+L RWHRMRG+  LW PG DHAGIATQ
Sbjct: 134  ATGE--TFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQ 191

Query: 390  VVVEKKLWREQGLSRHQLGREAFLQEVWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDP 449
             VVEK+LW+E+G+ RH+L REAFL+EVW+WKE KG  I  QL+ LG+SLDWDR CFTMD 
Sbjct: 192  AVVEKQLWKERGVRRHELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDV 251

Query: 450  KLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEK 509
              S AVTEAFVRL++ G++YR+ +LVNWSC L SAISDIEV+ + L G T L +PG    
Sbjct: 252  GSSVAVTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGHTQLRLPGCPTP 311

Query: 510  VEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFL 569
            V FG+L S A+ V G + D EVVV TTR ET+ GDVAVAVHP D+RY HL G+ + HP +
Sbjct: 312  VSFGLLFSVAFPVDG-EPDAEVVVGTTRPETLPGDVAVAVHPDDSRYTHLHGRQLRHPLM 370

Query: 570  SRSLPIVFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHGLEAISIMDSRGALINVPPPFL 629
             + LP++ D  V    GTGAVK+TPAH   D E+G RHGL  ++++   G + ++   +L
Sbjct: 371  GQPLPLITDYAVQPHVGTGAVKVTPAHSPADAEMGARHGLSPLNVIAEDGTMTSLCGDWL 430

Query: 630  -GLPRFEARKAVLVALKERGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQA 688
             GL RF AR+ ++  L E GLFRG++++PMV+P+C+RS DV+E LL+ QW+VRC EM   
Sbjct: 431  QGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQWFVRCQEMGAR 490

Query: 689  ASAAVTRGDLRILPEAHQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGED 748
            A+ AV  G L + P  HQ+ W  W  +I +WC+SRQLWWGH+IPAY V V D A   GE+
Sbjct: 491  AAKAVESGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHQIPAYLV-VEDHA--QGEE 547

Query: 749  PDGRYWVSGRNEAEAREKAAKEFGVSPDKISLQQDEDVLDTWFSSGLFPLSILGWPNQSE 808
                 WV GR+EAEARE AA+  G    +++L++D DVLDTWFSS LFP S LGWP ++ 
Sbjct: 548  D---CWVVGRSEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETP 604

Query: 809  DLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLG 868
            DL+ FYP +LLETG D+L FWV RMVMLG +LTG+LPF +V LH +VRD  GRKMSKSLG
Sbjct: 605  DLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLG 664

Query: 869  NVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCA 928
            NV+DP D+I G+ +Q L  +L + NLDP+E+      QK DFP GIPECGTDALRF LC+
Sbjct: 665  NVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRFTLCS 724

Query: 929  YMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIR 988
            +  Q  D++L V+ +   RHFCNK+WNA +F L  LG+ FVP P  +     S +D WI 
Sbjct: 725  HGVQAGDLHLSVSEVQSCRHFCNKIWNALRFILNALGEKFVPQPAEEL-SPSSPMDAWIL 783

Query: 989  SRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQT 1048
            SRL  A +   +GF   +   VT A + FWL+ LCDVYLE +KPVL    +       Q 
Sbjct: 784  SRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAVKPVLWHSPRPLG--PPQV 841

Query: 1049 LYTCLDVGLRLLSPFMPFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECS---WKDPEAE 1105
            L++C D+GLRLL+P MPF+ EEL+QRLP R P  PP+  ++  P PS CS   W+ PE E
Sbjct: 842  LFSCADLGLRLLAPLMPFLAEELWQRLPPR-PGCPPAPSISVAPYPSACSLEHWRQPELE 900

Query: 1106 AALELALSITRAVRSLRADYNLTRIRPDCFLEVADEATGALASAVSGYVQALASAGVVAV 1165
                    + + +R+LRA Y LT+ RP   L+ ++     L  A    +  L   G V +
Sbjct: 901  RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGL 960

Query: 1166 LALGAPAPQGCAVALASDRCSIHLQLQGLVDPARELGKLQAKRVEAQRQAQRLRERRAAS 1225
            L  GA AP G A A  SD   ++++LQGLVDP  +L  L A+R + Q+Q   L  R  + 
Sbjct: 961  LPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYKLQKQLDSLTARTPSE 1020

Query: 1226 GYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALFQKML 1264
            G       E     + KL   + EL K+D+A +  Q+++
Sbjct: 1021 G-------EAGTQRQQKLSSLQLELSKLDKAASHLQQLM 1052


>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
          Length = 1012

 Score =  193 bits (491), Expect = 8e-49
 Identities = 208/834 (24%), Positives = 337/834 (40%), Gaps = 125/834 (14%)

Query: 343  PPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWRE-QG 401
            PP   G  H+GHAL   ++D   R+H M G    + PG D  G+  ++ V  +L RE Q 
Sbjct: 115  PPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQN 174

Query: 402  LSRHQLGREAFLQEVWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVR 461
            LS  ++ ++A        +++K   I     + G   DW+   +T D K  A     F +
Sbjct: 175  LSAMEIRKKARSFAKAAIEKQKSAFI-----RWGIMADWNNCYYTFDGKYEAKQLRTFYQ 229

Query: 462  LHEEGIIYRSTRLVNWSCTLNSAISDIEVD-KKELTGRTL-LSVPGYKEKVEFGVLVSFA 519
            ++++G++YRS + V WS +  +A+++ E++   E   R++ +  P  K   +   L+   
Sbjct: 230  MYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLID-- 287

Query: 520  YKVQGSDSDEEVVVATTRIETMLGDVAVAVHPK--------------------------- 552
                   S   ++V TT+  T+  + AV   P+                           
Sbjct: 288  -----GSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVAS 342

Query: 553  --DTRYQ--------HLKGKNVIHPFL-SRSLPIVFDEFVDMDFGTGAVKITPAHDQNDY 601
              +T ++         L+     HP +  ++ P++    V M  GTG V   PAH   DY
Sbjct: 343  TLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDY 402

Query: 602  EVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVL-----VALKERGLFRGIEDN 656
             V  +H L    ++D  G   +V  P L        KAVL     V +K     + +   
Sbjct: 403  GVASQHNLPMDCLVDEDGVFTDVAGPEL------QNKAVLEEGTDVVIKMLQTAKNLLKE 456

Query: 657  PMVV---PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWM 713
              +V   P   R+K  V      QW++   ++  AA   + +  ++ +P +        M
Sbjct: 457  EKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKK--VKFIPGSALNGMVEMM 514

Query: 714  DNIREWCISRQLWWGHRIPAYFVTVSDP----------AVPPGEDPDGRYWVSGRNEAEA 763
            D    WCISRQ  WG  IP +     D            V   E      W +   E   
Sbjct: 515  DRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLL 574

Query: 764  REKAAKEFGVSPDKISLQQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGH 823
             ++   E G  PD +     +D+LD WF SG     +L  P+Q  DL +         G 
Sbjct: 575  PKEVLSEVG-GPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQRADLYL--------EGK 625

Query: 824  DILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQ 883
            D L  W    ++  +    R P++ V +H       G KMSKSLGNVI P DV+      
Sbjct: 626  DQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHP-DVV------ 678

Query: 884  GLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRI 943
                  +N   D S+                P  G D LR+ + A  +   ++ +  + +
Sbjct: 679  ------VNGGQDQSKE---------------PPYGADVLRWWV-ADSNVFTEVAIGPSVL 716

Query: 944  LGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQ 1003
               R   +KL N  +F L  +   F P   S P     ++D+++   L +      + ++
Sbjct: 717  NAARDDISKLRNTLRFLLGNVAD-FNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYK 775

Query: 1004 AYDFPAVTTAQYSFWLYELCDVYLECLKPVL---NGVDQVAAECARQTLYTCLDVGLRLL 1060
             YDF  V     +F+  EL + Y   +K  L      D     C +  L   LDV +R  
Sbjct: 776  QYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSC-QTALVEILDVIVRSF 834

Query: 1061 SPFMPFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSI 1114
            +P +P + EE+FQ +P    + P S+  T +   S   WK P  E A+E A ++
Sbjct: 835  APILPHLAEEVFQHIP--YIKEPKSVFRTGWISTSSI-WKKPGLEEAVESACAM 885


>gi|94721239 isoleucine tRNA synthetase [Homo sapiens]
          Length = 1262

 Score =  149 bits (375), Expect = 2e-35
 Identities = 185/796 (23%), Positives = 319/796 (40%), Gaps = 121/796 (15%)

Query: 343  PPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLW----- 397
            PP  TG  H GH L   I+D +TR+    G       G D  G+  +  ++K L      
Sbjct: 47   PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106

Query: 398  --REQGLSRHQLGREAFLQEVW-KWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAA 454
               + G++ +     A +     +WK          + +LG  +D+D    T+ P+   +
Sbjct: 107  DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158

Query: 455  VTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGV 514
            V   F +L+++G++YR  +++ +S   N+ +S+ E            S   YK+  +  V
Sbjct: 159  VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE------------SHQNYKDVQDPSV 206

Query: 515  LVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPK---------------------- 552
             V+F  +    D    +V  TT   T+  ++AV V+P+                      
Sbjct: 207  FVTFPLE---EDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARL 263

Query: 553  ------DTRYQ--------HLKGKN---VIHPFL----SRSLPIVFDEFVDMDFGTGAVK 591
                  ++ Y+        +LKGK    +   FL    + +  ++ D +V  + GTG V 
Sbjct: 264  SALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323

Query: 592  ITPAHDQNDYEVGQ-----RHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKE 646
              P     DY V       R     +  +D+ G        F G    +A K+++  LKE
Sbjct: 324  QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKE 383

Query: 647  RGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRI-LPE-A 704
            +G            P C RS   +     P W+VR   M       +   DL   +PE  
Sbjct: 384  QGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQL---LRNNDLCYWVPELV 440

Query: 705  HQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAR 764
             ++ +  W+ + R+W ISR  +WG  IP +     +  V  G   +    +SG   ++  
Sbjct: 441  REKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEE-LSGAKISDLH 499

Query: 765  EKAAKEFGVSP--DKISLQQDEDVLDTWFSSGLFPLSILGWPNQSE-DLSVFYPGTLLET 821
             ++     +     K SL +  +V D WF SG  P + + +P +++ +    +P   +  
Sbjct: 500  RESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAE 559

Query: 822  GHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGIS 881
            G D    W   +++L   L G+ PF+ V ++ +V  + G+KMSK   N  DP+ +I    
Sbjct: 560  GIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYG 619

Query: 882  LQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVN 941
               L   L+NS +  +E  + KE           E   D L+  L  + +  R +  +V 
Sbjct: 620  ADALRLYLINSPVVRAENLRFKE-----------EGVRDVLKDVLLPWYNAYRFLIQNVL 668

Query: 942  RILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQG 1001
            R L        L+N               SP        ++ DRWI S +   +      
Sbjct: 669  R-LQKEEEIEFLYNENTVR---------ESP--------NITDRWILSFMQSLIGFFETE 710

Query: 1002 FQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAEC--ARQTLYTCLDVGLRL 1059
              AY    V      F +  L + Y+   +  L G +    +C  A +TL++ L    RL
Sbjct: 711  MAAYRLYTVVPRLVKF-VDILTNWYVRMNRRRLKG-ENGMEDCVMALETLFSVLLSLCRL 768

Query: 1060 LSPFMPFVTEELFQRL 1075
            ++P+ PF+TE ++Q L
Sbjct: 769  MAPYTPFLTELMYQNL 784


>gi|94721241 isoleucine tRNA synthetase [Homo sapiens]
          Length = 1262

 Score =  149 bits (375), Expect = 2e-35
 Identities = 185/796 (23%), Positives = 319/796 (40%), Gaps = 121/796 (15%)

Query: 343  PPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLW----- 397
            PP  TG  H GH L   I+D +TR+    G       G D  G+  +  ++K L      
Sbjct: 47   PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106

Query: 398  --REQGLSRHQLGREAFLQEVW-KWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAA 454
               + G++ +     A +     +WK          + +LG  +D+D    T+ P+   +
Sbjct: 107  DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158

Query: 455  VTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGV 514
            V   F +L+++G++YR  +++ +S   N+ +S+ E            S   YK+  +  V
Sbjct: 159  VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE------------SHQNYKDVQDPSV 206

Query: 515  LVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPK---------------------- 552
             V+F  +    D    +V  TT   T+  ++AV V+P+                      
Sbjct: 207  FVTFPLE---EDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARL 263

Query: 553  ------DTRYQ--------HLKGKN---VIHPFL----SRSLPIVFDEFVDMDFGTGAVK 591
                  ++ Y+        +LKGK    +   FL    + +  ++ D +V  + GTG V 
Sbjct: 264  SALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323

Query: 592  ITPAHDQNDYEVGQ-----RHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKE 646
              P     DY V       R     +  +D+ G        F G    +A K+++  LKE
Sbjct: 324  QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKE 383

Query: 647  RGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRI-LPE-A 704
            +G            P C RS   +     P W+VR   M       +   DL   +PE  
Sbjct: 384  QGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQL---LRNNDLCYWVPELV 440

Query: 705  HQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAR 764
             ++ +  W+ + R+W ISR  +WG  IP +     +  V  G   +    +SG   ++  
Sbjct: 441  REKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEE-LSGAKISDLH 499

Query: 765  EKAAKEFGVSP--DKISLQQDEDVLDTWFSSGLFPLSILGWPNQSE-DLSVFYPGTLLET 821
             ++     +     K SL +  +V D WF SG  P + + +P +++ +    +P   +  
Sbjct: 500  RESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAE 559

Query: 822  GHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGIS 881
            G D    W   +++L   L G+ PF+ V ++ +V  + G+KMSK   N  DP+ +I    
Sbjct: 560  GIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYG 619

Query: 882  LQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVN 941
               L   L+NS +  +E  + KE           E   D L+  L  + +  R +  +V 
Sbjct: 620  ADALRLYLINSPVVRAENLRFKE-----------EGVRDVLKDVLLPWYNAYRFLIQNVL 668

Query: 942  RILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQG 1001
            R L        L+N               SP        ++ DRWI S +   +      
Sbjct: 669  R-LQKEEEIEFLYNENTVR---------ESP--------NITDRWILSFMQSLIGFFETE 710

Query: 1002 FQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAEC--ARQTLYTCLDVGLRL 1059
              AY    V      F +  L + Y+   +  L G +    +C  A +TL++ L    RL
Sbjct: 711  MAAYRLYTVVPRLVKF-VDILTNWYVRMNRRRLKG-ENGMEDCVMALETLFSVLLSLCRL 768

Query: 1060 LSPFMPFVTEELFQRL 1075
            ++P+ PF+TE ++Q L
Sbjct: 769  MAPYTPFLTELMYQNL 784


>gi|4503481 eukaryotic translation elongation factor 1 gamma [Homo
           sapiens]
          Length = 437

 Score =  130 bits (326), Expect = 1e-29
 Identities = 97/292 (33%), Positives = 149/292 (51%), Gaps = 41/292 (14%)

Query: 3   TLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPP-----PTSRTP-----F 52
           TLY   +P+ + + +ALIAA+Y          GA  R+   PP      T+RTP     F
Sbjct: 5   TLYT--YPENWRAFKALIAAQYS---------GAQVRVLSAPPHFHFGQTNRTPEFLRKF 53

Query: 53  PPPRLPALEQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAAC 112
           P  ++PA E G  G  V+ + A+A  +    L G     AA +VQ WVS+AD++++P A 
Sbjct: 54  PAGKVPAFE-GDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQ-WVSFADSDIVPPAS 111

Query: 113 GATLPALGL-RSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLP 171
               P LG+   + Q  +     + R L  L+ +L+  T+L GE  TLAD+  V  LL  
Sbjct: 112 TWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWL 171

Query: 172 FRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVL------YSGARPLSHQPGPEAP 225
           ++ VL+P  R+ + N  RWF+TC+ QP+FRAVLGEV L      +   +    QP  + P
Sbjct: 172 YKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTP 231

Query: 226 ALPKTAAQLKKEAKKREKLEKFQQKQKIQQQ--QPPPGEKKPKPEKREKRDP 275
                    +KE   RE+ +K Q ++K +++   P P E+  + E+    +P
Sbjct: 232 ---------RKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEP 274


>gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo
           sapiens]
          Length = 903

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 96/453 (21%), Positives = 167/453 (36%), Gaps = 54/453 (11%)

Query: 312 WWEQQGFFKPEYGR-PNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRM 370
           WW Q+   K +  +      + P+   +   P P+  G LH+GH     I D++ R+ +M
Sbjct: 62  WWHQR--IKEQASKISEADKSKPKFYVLSMFPYPS--GKLHMGHVRVYTISDTIARFQKM 117

Query: 371 RGETTLWNPGCDHAGI-ATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWKEEKGDRIYH 429
           RG   +   G D  G+ A    VE+ L  +                   W +     +  
Sbjct: 118 RGMQVINPMGWDAFGLPAENAAVERNLHPQS------------------WTQSNIKHMRK 159

Query: 430 QLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIE 489
           QL +LG    WDR   T  P         F++L+E G+ Y+   LVNW     + +++ +
Sbjct: 160 QLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQ 219

Query: 490 VDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAV 549
           VD+   + R+   V     +  F    ++A  +Q + +D         +    G   +  
Sbjct: 220 VDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD---------LPEWYGIKGMQA 270

Query: 550 H-PKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHG 608
           H   D    HL     +H   +      +    +  +GT  V I+P+H         +  
Sbjct: 271 HWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEA 330

Query: 609 LEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGI-----------EDNP 657
           L  ++++  +  L     P + +     ++  +V L +  L   +           ED  
Sbjct: 331 LR-MALVPGKDCL----TPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTI 385

Query: 658 MVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRT--WHAWMDN 715
           +   L     +V+E L  P    R    A+          L +  +A  +        D 
Sbjct: 386 LAQTLGLAYSEVIETL--PDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDK 443

Query: 716 IREWCISRQLWWGHRIPAYFVTVSDPAVPPGED 748
           +++W ISRQ +WG  IP     V  P   P ED
Sbjct: 444 LKDWLISRQRYWGTPIPIVHCPVCGPTPVPLED 476


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 25/81 (30%), Positives = 51/81 (62%), Gaps = 8/81 (9%)

Query: 219 QPGPEAPALP----KTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRD 274
           QP PE   L     +T   L+++ +++++ ++ QQ+Q  QQQQ  P ++ P+P+ ++++ 
Sbjct: 196 QPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQ--QQQQQQPQQQPPQPQTQQQQQ 253

Query: 275 PGVITYDLPTPPGEKKDVSGP 295
           P ++ Y+ P+ PG   ++SGP
Sbjct: 254 PALVNYNRPSGPG--PELSGP 272


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 25/81 (30%), Positives = 51/81 (62%), Gaps = 8/81 (9%)

Query: 219 QPGPEAPALP----KTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRD 274
           QP PE   L     +T   L+++ +++++ ++ QQ+Q  QQQQ  P ++ P+P+ ++++ 
Sbjct: 196 QPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQ--QQQQQQPQQQPPQPQTQQQQQ 253

Query: 275 PGVITYDLPTPPGEKKDVSGP 295
           P ++ Y+ P+ PG   ++SGP
Sbjct: 254 PALVNYNRPSGPG--PELSGP 272


>gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]
          Length = 593

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 12/116 (10%)

Query: 783 DEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFF----WVARMVMLGL 838
           D   +  W  + +  L+++G+PN   +   ++P T    G DIL F    W A ++  G+
Sbjct: 272 DSQTIYVWLDALVNYLTVIGYPNA--EFKSWWPATSHIIGKDILKFHAIYWPAFLLGAGM 329

Query: 839 KLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNL 894
               R+    V+ H  V    G+KMSKSLGNV+DP   +   ++ G    LL   +
Sbjct: 330 SPPQRIC---VHSHWTVC---GQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGV 379


>gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
          Length = 1176

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 143/745 (19%), Positives = 242/745 (32%), Gaps = 187/745 (25%)

Query: 313 WEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRG 372
           W+ +  F  E    N+     +G + +  P P + G LHLGH  + +  +    + R++G
Sbjct: 24  WDTERVF--EVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKG 81

Query: 373 ETTLWNPGCDHAGIATQVVVEK-------------------------------------- 394
           +  L+  G    G+  +   +K                                      
Sbjct: 82  KCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAK 141

Query: 395 ----KLWREQGLSRHQLGREAFL----QEVWKWKEEKGDRIY------HQLKKLGSSLDW 440
               K   + G S++Q G    L    +E+ K+ E +    Y        LK++G  +DW
Sbjct: 142 GKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDW 201

Query: 441 DRACFTMD--PKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGR 498
            R+  T D  P   + V   F+ L E   I    R   +S        D +    E  G 
Sbjct: 202 RRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVG- 260

Query: 499 TLLSVPGYKEKVEFGVLVSFAYKVQG-SDSDEEVVVATTRIETMLGDVAVAVHP------ 551
                P     ++  VL  +  K+ G    +  +V AT R ETM G     V P      
Sbjct: 261 -----PQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIG 315

Query: 552 ----------------KDTRYQHLKGKNVIHPFL-----------SRSLPIVFDEFVDM- 583
                           ++  YQ     N + P +           S S P+   + + + 
Sbjct: 316 FETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVL 375

Query: 584 -------DFGTGAVKITPAHDQNDY----EVGQRHGLEAISIMDSRGALINVPPPFLGLP 632
                  D GTG V   P+   +D     ++ ++  L A   +     L   P P + +P
Sbjct: 376 PMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIP 435

Query: 633 RFEARKAV----------------LVALKERGLFRGIEDNPMVV---------------- 660
            F    AV                L   KE+   +G  +  M+V                
Sbjct: 436 GFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQ 495

Query: 661 -----------------PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPE 703
                             + +RS D     L  QWY+  GE       +    +L    E
Sbjct: 496 KKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCE 555

Query: 704 AHQRTWHAWMDNIREWCISRQLWWGHRIP----AYFVTVSDPAVPPGEDPDGRYWVSGRN 759
             +R + A +  ++E   SR    G  +P        ++SD  +             G  
Sbjct: 556 ETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNL 615

Query: 760 EAEAREKAAKEFGVSPDKISLQQDEDVLD-TWFSSGLFPLSILG---WPNQSEDLSVFYP 815
             +A        G+ P     Q  ++V D  +F    FP + +         ++   +YP
Sbjct: 616 HGQAE----SPLGIRPQ----QMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQEFEFWYP 667

Query: 816 GTLLETGHDI----LFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAH----GRKMSKSL 867
             L  +G D+    L +++   V +  + + + P       A+  + H      KMSKS 
Sbjct: 668 VDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWP------TAVRANGHLLLNSEKMSKST 721

Query: 868 GNVIDPLDVIYGISLQGLHNQLLNS 892
           GN +     I   S  G+   L ++
Sbjct: 722 GNFLTLTQAIDKFSADGMRLALADA 746


>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
          Length = 900

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 88/400 (22%), Positives = 150/400 (37%), Gaps = 77/400 (19%)

Query: 27  AGEGPGWGGAHPRICLQPPPTSRTPF-PPPRLPALEQGPGGLWVWGATAVAQLLWPAGLG 85
           A  G   G A   I    P     PF   P++P L+   G  +++  +A+ +  +     
Sbjct: 17  AAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGN-YLFSTSAICRYFFLLS-- 73

Query: 86  GPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLGALGRALSPLEEW 145
              G     L  QW+ +  TEL PA   A    +      +D   VLG++ RAL+ ++  
Sbjct: 74  ---GWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGED---VLGSVRRALTHIDHS 127

Query: 146 LRLHT--YLAGEAPTLADLAAVTALLLPFRYVLDPP-ARRIWNNVTRWFVTCVRQPEFRA 202
           L      +LAGE  +LAD+    AL   +  + DP       + +  WF T   Q   + 
Sbjct: 128 LSRQNCPFLAGETESLADIVLWGAL---YPLLQDPAYLPEELSALHSWFQTLSTQEPCQR 184

Query: 203 VLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGE 262
               V+   G   L                        R  L+K        Q QP P E
Sbjct: 185 AAETVLKQQGVLAL------------------------RPYLQK--------QPQPSPAE 212

Query: 263 KKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPE 322
            +    + E+ +   ++         +++++              AW    E     +P+
Sbjct: 213 GRAVTNEPEEEELATLS---------EEEIA----------MAVTAWEKGLESLPPLRPQ 253

Query: 323 YGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQ-DSLTRWHRMRGETTLWNPGC 381
              P +  A  R V ++    P V    HLG+ +   +  D   R+ R+R   TL+  G 
Sbjct: 254 Q-NPVLPVAGERNV-LITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGT 311

Query: 382 DHAGIATQVVVEKKLWREQGLSRHQLGREAFL--QEVWKW 419
           D  G AT+    K L  E+GL+  ++  +  +   ++++W
Sbjct: 312 DEYGTATET---KAL--EEGLTPQEICDKYHIIHADIYRW 346


>gi|4557489 cone-rod homeobox protein [Homo sapiens]
          Length = 299

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 37/109 (33%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 227 LPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREK-RDPGVITYDLPTP 285
           LP++  Q+  +  +R K  + +Q+QK QQQQPP G+ K +P KR+    P   T   P P
Sbjct: 78  LPESRVQVWFK-NRRAKCRQQRQQQK-QQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDP 135

Query: 286 PGEKKDVSGPMP-DSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANP 333
            G     S P+P  S SP    A    W        PE  R  + A+ P
Sbjct: 136 LGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGP 184


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 17/91 (18%)

Query: 223 EAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDL 282
           +APA PKT  + KK++KK E  +K   K K+++++ P  EK  + +   K++       +
Sbjct: 846 KAPATPKT--EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903

Query: 283 PTP---------------PGEKKDVSGPMPD 298
           PTP               P EK +V+   PD
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 232  AQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEK-- 289
            A+ K+ +K  EK E   +K+  ++++    E+KPK E + K D   ++ +   P  EK  
Sbjct: 936  AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995

Query: 290  KDVSGPMPDSYSP 302
            K  S    DS  P
Sbjct: 996  KSSSTDQKDSKPP 1008



 Score = 34.3 bits (77), Expect = 0.77
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 215 PLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKI---QQQQPPPGEKKPKPEKRE 271
           P    P P+     + A +  KE+K   K E+ + K+K+   +++ P   E K   + +E
Sbjct: 865 PKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924

Query: 272 -----KRDPGVITYDLPTPPGEKKDVSGPMPDS 299
                K++P       P+ P EKK+ +    D+
Sbjct: 925 KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 5/56 (8%)

Query: 222 PEAPALPKTAAQLKKE-----AKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREK 272
           P  PA  K AA  KK+     AKK E+  K + K K   +       KPK EK EK
Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996


>gi|157743252 pecanex-like 3 [Homo sapiens]
          Length = 2034

 Score = 38.9 bits (89), Expect = 0.031
 Identities = 45/151 (29%), Positives = 58/151 (38%), Gaps = 40/151 (26%)

Query: 30   GPGWG----------GAHPRICLQPPPTSRTPFPPPRLP--------ALEQGPGGLWVWG 71
            GPGWG          G  P +   PPP  R P PPP  P        +   GPG L   G
Sbjct: 1874 GPGWGPRSSLSGSGDGRPPPLLQWPPP--RLPGPPPASPIPTEGPRTSRPPGPGLLSSEG 1931

Query: 72   ATAVAQLLWPAGLGGPGG-------------SRAAVLVQQWVSYA-----DTELIPAACG 113
             +    L    GLGG  G             S+A + +   +S +      TE  P    
Sbjct: 1932 PSGKWSLGGRKGLGGSDGEPASGSPKGGTPKSQAPLDLSLSLSLSLSPDVSTEASPPRAS 1991

Query: 114  ATLPALGLRSSAQDPQAVLGALGRALSPLEE 144
              +P L   SSA +    +GALG   +P+EE
Sbjct: 1992 QDIPCLD--SSAPESGTPMGALGDWPAPIEE 2020


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 37.7 bits (86), Expect = 0.070
 Identities = 20/80 (25%), Positives = 40/80 (50%)

Query: 217 SHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPG 276
           S  P  + P + K + + KK+ KK ++ E+ ++K+K ++++  P  KK K  K ++    
Sbjct: 827 SKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTK 886

Query: 277 VITYDLPTPPGEKKDVSGPM 296
                   PPG ++    P+
Sbjct: 887 GKKKSKKQPPGSEEAAGEPV 906


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 37.7 bits (86), Expect = 0.070
 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 22/144 (15%)

Query: 106 ELIPA---ACGATLPALGLRSSAQDPQAVLGALGRALSPLEEWLRLHT--YLAGEAPTLA 160
           EL+P    ACG T          Q+ Q +L  L      L  WL +H    +A E  T  
Sbjct: 282 ELMPRFEEACGRTTET----EKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKM 337

Query: 161 DLAAVTALLLPFRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQP 220
           ++  ++ +L         P  +I N V   F T V++     + G VVL    +PL    
Sbjct: 338 NIQNISIVL--------SPTVQISNRVLYVFFTHVQE-----LFGNVVLKQVMKPLRWSN 384

Query: 221 GPEAPALPKTAAQLKKEAKKREKL 244
               P LP+T A +K+E +++E L
Sbjct: 385 MATMPTLPETQAGIKEEIRRQEFL 408


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 37.7 bits (86), Expect = 0.070
 Identities = 54/204 (26%), Positives = 79/204 (38%), Gaps = 49/204 (24%)

Query: 154  GEAPTLADLAAVTALLLPFRYVLDPPARRIWNNVTRWFVTCVRQPEFRA--VLGEVVLYS 211
            GEAPT A  A ++A L    Y +DP   +          T +   +F    V G    Y+
Sbjct: 3262 GEAPT-ATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYA 3320

Query: 212  GARPLSHQPG------------PEAPALPKTAAQLK---------------KEAKKREKL 244
               P + Q G            P +PAL +    L                +EA ++++ 
Sbjct: 3321 PQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQ 3380

Query: 245  EKFQQKQ--KIQQQQP-------PPG---------EKKPKPEKREKRDPGVITYDLPTPP 286
             + QQ+Q  K+QQQQP       PPG         ++ PKPE+ +K  P  ++  LP  P
Sbjct: 3381 RQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEE-QKNTPREVSPLLPKLP 3439

Query: 287  GEKKDVSGPMPDSYSPRYVEAAWY 310
             E +  S      Y P  V    Y
Sbjct: 3440 EEPEAESKSADSLYDPFIVPKVQY 3463


>gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens]
          Length = 332

 Score = 37.0 bits (84), Expect = 0.12
 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 13/98 (13%)

Query: 74  AVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLG 133
           A+   L   GLGG G +   + +        +EL P     T  A+GL   A    A+LG
Sbjct: 211 ALRSALAVLGLGGVGAAFTCITIYS------SELFPTVLRMT--AVGLGQMAARGGAILG 262

Query: 134 ALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLP 171
            L R L     WL L  Y  G  P L+ LA   ALLLP
Sbjct: 263 PLVRLLGVHGPWLPLLVY--GTVPVLSGLA---ALLLP 295


>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
          Length = 553

 Score = 37.0 bits (84), Expect = 0.12
 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 13/98 (13%)

Query: 74  AVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLG 133
           A+   L   GLGG G +   + +        +EL P     T  A+GL   A    A+LG
Sbjct: 432 ALRSALAVLGLGGVGAAFTCITIYS------SELFPTVLRMT--AVGLGQMAARGGAILG 483

Query: 134 ALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLP 171
            L R L     WL L  Y  G  P L+ LA   ALLLP
Sbjct: 484 PLVRLLGVHGPWLPLLVY--GTVPVLSGLA---ALLLP 516


>gi|20070228 nucleobindin 1 [Homo sapiens]
          Length = 461

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 9/101 (8%)

Query: 195 VRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEK-FQQKQKI 253
           +R+ E      E  L + A+ LS     E  AL ++  +L  EA+KRE  +     +Q+ 
Sbjct: 347 LRRFEEELAAREAELNAKAQRLSQ----ETEALGRSQGRL--EAQKRELQQAVLHMEQRK 400

Query: 254 QQQQPPPGEKKPK--PEKREKRDPGVITYDLPTPPGEKKDV 292
           QQQQ   G K P   PE + K  P      +P P G++K+V
Sbjct: 401 QQQQQQQGHKAPAAHPEGQLKFHPDTDDVPVPAPAGDQKEV 441


>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
            sapiens]
          Length = 1499

 Score = 35.8 bits (81), Expect = 0.27
 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 20/113 (17%)

Query: 225  PALPKTAAQLKKEAKKREKLEKFQQ--KQKIQQQQPPPGEKKPKPEKREKRDPGVITY-D 281
            P+L K  ++L  E +  + L       + K+  + PPP   KPKP    +   G ++Y D
Sbjct: 1003 PSLSKDHSKLSMELEGNDGLSFIMSNFESKLNNKVPPP--VKPKPPVHFEITKGDLSYLD 1060

Query: 282  LPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPR 334
                 G++K VS                 PW  Q GF   +Y  P  +   PR
Sbjct: 1061 QGHRDGQRKSVSSS---------------PWLPQDGFDPSDYAEPMDAVVKPR 1098


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 35.8 bits (81), Expect = 0.27
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 223 EAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKK--PKPEKRE-KRDPGVIT 279
           E P   +   ++KKE KK EK E    K++++++ PP   KK   K EK+E K++     
Sbjct: 673 EKPKKEEVKKEVKKEIKKEEKKE---PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK 729

Query: 280 YDLPTPPGEKKDVSGPMPDSYSP 302
            ++   P + K  S P+ ++  P
Sbjct: 730 KEIKKLPKDAKKSSTPLSEAKKP 752


>gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens]
          Length = 581

 Score = 35.8 bits (81), Expect = 0.27
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 26/84 (30%)

Query: 212 GARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKRE 271
           G R L   PGPE P +P     L        +L + +Q+Q+ QQQ PPP           
Sbjct: 147 GGRLLLQPPGPELPPVPFPLQDLVPLG----RLSRGEQQQQQQQQPPPP----------- 191

Query: 272 KRDPGVITYDLPTPPGEKKDVSGP 295
                      P PPG  + ++GP
Sbjct: 192 -----------PPPPGPLRPLAGP 204


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 35.4 bits (80), Expect = 0.35
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 214 RPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKR 273
           +P S   GP + + P  A  L+ +A +  K      ++  Q+QQ P G  +P+ E   + 
Sbjct: 58  QPQSGSSGPSSHS-PPAAMALQSQASEEAK---GPWQEADQEQQEPVGSPEPESEPEPEP 113

Query: 274 DPGVITYDLPTPPGEKKDVSGPMPD 298
           +P  +    P PP E +    P+PD
Sbjct: 114 EPEPV----PVPPPEPQPEPQPLPD 134


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 35.0 bits (79), Expect = 0.45
 Identities = 17/67 (25%), Positives = 35/67 (52%)

Query: 235 KKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSG 294
           ++  K +++ ++ QQ+Q+ QQQQP P   + + +++EK        + P    +K+D+  
Sbjct: 488 RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLK 547

Query: 295 PMPDSYS 301
              D  S
Sbjct: 548 EKTDDTS 554


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 35.0 bits (79), Expect = 0.45
 Identities = 17/67 (25%), Positives = 35/67 (52%)

Query: 235 KKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSG 294
           ++  K +++ ++ QQ+Q+ QQQQP P   + + +++EK        + P    +K+D+  
Sbjct: 488 RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLK 547

Query: 295 PMPDSYS 301
              D  S
Sbjct: 548 EKTDDTS 554


>gi|196114999 special AT-rich sequence binding protein 1 [Homo
           sapiens]
          Length = 763

 Score = 35.0 bits (79), Expect = 0.45
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 15/123 (12%)

Query: 169 LLPFRYVLDPPARRIWNNVT--RWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPA 226
           LL ++    P  R +W N++  R F++ + QPE  A+      Y       H  G   P 
Sbjct: 531 LLRWKEDPSPENRTLWENLSMIRRFLS-LPQPERDAI------YEQESNAVHHHGDRPPH 583

Query: 227 LPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPP 286
           +      +   A++ ++ ++ QQ+Q+ QQQ PPP + + +P+   +  P   T   P   
Sbjct: 584 I------IHVPAEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAES 637

Query: 287 GEK 289
            E+
Sbjct: 638 DEE 640


>gi|4506791 special AT-rich sequence binding protein 1 [Homo
           sapiens]
          Length = 763

 Score = 35.0 bits (79), Expect = 0.45
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 15/123 (12%)

Query: 169 LLPFRYVLDPPARRIWNNVT--RWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPA 226
           LL ++    P  R +W N++  R F++ + QPE  A+      Y       H  G   P 
Sbjct: 531 LLRWKEDPSPENRTLWENLSMIRRFLS-LPQPERDAI------YEQESNAVHHHGDRPPH 583

Query: 227 LPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPP 286
           +      +   A++ ++ ++ QQ+Q+ QQQ PPP + + +P+   +  P   T   P   
Sbjct: 584 I------IHVPAEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAES 637

Query: 287 GEK 289
            E+
Sbjct: 638 DEE 640


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 35.0 bits (79), Expect = 0.45
 Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 4/62 (6%)

Query: 214  RPLSHQP-GPEAPALPKTAAQLKKEAKKREKLEKFQQKQK-IQQQQPPPGEKKPKPEKRE 271
            R   H+P GP  P +  ++ +  +E ++ E+L K Q+KQ+ I+QQQ     KK K +K E
Sbjct: 1756 RKARHRPHGPLLPTIEDSSEE--EELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813

Query: 272  KR 273
             R
Sbjct: 1814 LR 1815



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 8/108 (7%)

Query: 187 VTRWFVTCVRQPEFRAVLGEVV-LYSGARP-LSHQPGPEAPALPKTAAQLKKEAKKREKL 244
           V  W   C+     RA+ G++  + S  +P L   P     A+ K++ Q ++ + K++  
Sbjct: 632 VKEWL--CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA 689

Query: 245 EKFQQKQKIQQQQPPPGEKKP----KPEKREKRDPGVITYDLPTPPGE 288
            K    +  + ++PPP  K+P     P  + K+ P   +   P PP E
Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 11/141 (7%)

Query: 214 RPLSHQPGPEA----PALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEK 269
           +P S QPGP+A    P + KT AQ    AK   + +    K   QQ       K P P K
Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ-QVGTPKPLAQQPGLQSPAKAPGPTK 438

Query: 270 R--EKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPN 327
              ++  PG I      P       +GP   +  P  +     P  +Q G  KP   +P 
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGP---TKPPSQLPGPAKPPPQQPGPAKPPPQQPG 495

Query: 328 VSAANPRGVFMMCIPPPNVTG 348
            SA  P        PPP   G
Sbjct: 496 -SAKPPSQQPGSTKPPPQQPG 515


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,560,603
Number of Sequences: 37866
Number of extensions: 2982286
Number of successful extensions: 15663
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 132
Number of HSP's that attempted gapping in prelim test: 14541
Number of HSP's gapped (non-prelim): 1031
length of query: 1264
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1150
effective length of database: 13,930,794
effective search space: 16020413100
effective search space used: 16020413100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.