BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5453882 phosphorylase kinase gamma subunit 1 [Homo sapiens] (387 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5453882 phosphorylase kinase gamma subunit 1 [Homo sapiens] 785 0.0 gi|4505785 phosphorylase kinase, gamma 2 (testis) [Homo sapiens] 512 e-145 gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 203 2e-52 gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 203 2e-52 gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 203 2e-52 gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 203 2e-52 gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 203 2e-52 gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 203 2e-52 gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 202 5e-52 gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 202 5e-52 gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 201 9e-52 gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 201 9e-52 gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 201 9e-52 gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 201 9e-52 gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 201 9e-52 gi|149589021 doublecortin-like kinase 3 [Homo sapiens] 198 6e-51 gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 197 1e-50 gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 197 2e-50 gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 196 2e-50 gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 196 3e-50 gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 196 3e-50 gi|4557511 death-associated protein kinase 3 [Homo sapiens] 186 2e-47 gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is... 186 2e-47 >gi|5453882 phosphorylase kinase gamma subunit 1 [Homo sapiens] Length = 387 Score = 785 bits (2027), Expect = 0.0 Identities = 387/387 (100%), Positives = 387/387 (100%) Query: 1 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS 60 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS Sbjct: 1 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS 60 Query: 61 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV 120 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV Sbjct: 61 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV 120 Query: 121 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER 180 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER Sbjct: 121 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER 180 Query: 181 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR 240 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR Sbjct: 181 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR 240 Query: 241 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS 300 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS Sbjct: 241 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS 300 Query: 301 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK 360 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK Sbjct: 301 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK 360 Query: 361 KGQQQNRAALFENTPKAVLLSLAEEDY 387 KGQQQNRAALFENTPKAVLLSLAEEDY Sbjct: 361 KGQQQNRAALFENTPKAVLLSLAEEDY 387 >gi|4505785 phosphorylase kinase, gamma 2 (testis) [Homo sapiens] Length = 406 Score = 512 bits (1319), Expect = e-145 Identities = 240/372 (64%), Positives = 306/372 (82%), Gaps = 1/372 (0%) Query: 4 DEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEE 63 ++ LPD +A++FY+ Y+PK+++GRGVSSVVRRC+H+ T E+AVK+++VT SPE+ Sbjct: 8 EDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE-RLSPEQ 66 Query: 64 VRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLS 123 + E+REAT +E ILR+V+GHP+II L D+YE+++F FLVFDLM++GELFDYLTEKV LS Sbjct: 67 LEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALS 126 Query: 124 EKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLRE 183 EKETR IMR+LLE + LH NIVHRDLKPENILLDDNM I+L+DFGFSC LEPGE+LRE Sbjct: 127 EKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRE 186 Query: 184 VCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIM 243 +CGTP YLAPEI++CSM+E HPGYGKEVD+W+ GVI++TLLAGSPPFWHR+Q+LMLRMIM Sbjct: 187 LCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIM 246 Query: 244 SGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRG 303 G YQF SPEWDD S TVKDL+SR L V P+ R TAE+AL HPFF++ + + +PR Sbjct: 247 EGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQ 306 Query: 304 KFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQ 363 +F+V TVLA+ R+ RV+P+T+ ++RDPYALR +R LID AFR+YGHWVKKG+ Sbjct: 307 RFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGE 366 Query: 364 QQNRAALFENTP 375 QQNRAALF++ P Sbjct: 367 QQNRAALFQHRP 378 >gi|212549756 calcium/calmodulin-dependent protein kinase II delta isoform 4 [Homo sapiens] Length = 489 Score = 203 bits (516), Expect = 2e-52 Identities = 120/317 (37%), Positives = 173/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E LG+G SVVRRC+ PT QEYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H IVHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VDMW+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHFS 300 PEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F+ Sbjct: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26667183 calcium/calmodulin-dependent protein kinase II delta isoform 1 [Homo sapiens] Length = 478 Score = 203 bits (516), Expect = 2e-52 Identities = 120/317 (37%), Positives = 173/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E LG+G SVVRRC+ PT QEYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H IVHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VDMW+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHFS 300 PEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F+ Sbjct: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|212549753 calcium/calmodulin-dependent protein kinase II delta isoform 5 [Homo sapiens] Length = 492 Score = 203 bits (516), Expect = 2e-52 Identities = 120/317 (37%), Positives = 173/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E LG+G SVVRRC+ PT QEYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H IVHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VDMW+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHFS 300 PEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F+ Sbjct: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26667186 calcium/calmodulin-dependent protein kinase II delta isoform 1 [Homo sapiens] Length = 478 Score = 203 bits (516), Expect = 2e-52 Identities = 120/317 (37%), Positives = 173/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E LG+G SVVRRC+ PT QEYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H IVHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VDMW+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHFS 300 PEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F+ Sbjct: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26667189 calcium/calmodulin-dependent protein kinase II delta isoform 2 [Homo sapiens] Length = 478 Score = 203 bits (516), Expect = 2e-52 Identities = 120/317 (37%), Positives = 173/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E LG+G SVVRRC+ PT QEYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H IVHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VDMW+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHFS 300 PEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F+ Sbjct: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26667180 calcium/calmodulin-dependent protein kinase II delta isoform 3 [Homo sapiens] Length = 499 Score = 203 bits (516), Expect = 2e-52 Identities = 120/317 (37%), Positives = 173/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E LG+G SVVRRC+ PT QEYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H IVHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VDMW+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHFS 300 PEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F+ Sbjct: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|25952118 calcium/calmodulin-dependent protein kinase II alpha isoform 2 [Homo sapiens] Length = 478 Score = 202 bits (513), Expect = 5e-52 Identities = 118/318 (37%), Positives = 174/318 (54%), Gaps = 31/318 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F E Y+ E LG+G SVVRRC+ QEYA K+I+ S + ++L +E Sbjct: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTK---KLSARDHQKLE----REA 61 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ +L+FDL+ GELF+ + + SE + ++ +L Sbjct: 62 RICRLLK-HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR--EVCGTPSY 190 E + H++ +VHRDLKPEN+LL + +KL DFG + ++E GE+ GTP Y Sbjct: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVE-GEQQAWFGFAGTPGY 179 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG 250 L+PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F Sbjct: 180 LSPEVLR------KDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233 Query: 251 SPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHF 299 SPEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F Sbjct: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKF 293 Query: 300 SPRGKFKVIALTVLASVR 317 + R K K LT + + R Sbjct: 294 NARRKLKGAILTTMLATR 311 >gi|25952114 calcium/calmodulin-dependent protein kinase II alpha isoform 1 [Homo sapiens] Length = 489 Score = 202 bits (513), Expect = 5e-52 Identities = 118/318 (37%), Positives = 174/318 (54%), Gaps = 31/318 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F E Y+ E LG+G SVVRRC+ QEYA K+I+ S + ++L +E Sbjct: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTK---KLSARDHQKLE----REA 61 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ +L+FDL+ GELF+ + + SE + ++ +L Sbjct: 62 RICRLLK-HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR--EVCGTPSY 190 E + H++ +VHRDLKPEN+LL + +KL DFG + ++E GE+ GTP Y Sbjct: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVE-GEQQAWFGFAGTPGY 179 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG 250 L+PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F Sbjct: 180 LSPEVLR------KDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233 Query: 251 SPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-----------QQYLVEEVRHF 299 SPEWD + KDL+++ L + P R TA EAL HP+ +Q V+ ++ F Sbjct: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKF 293 Query: 300 SPRGKFKVIALTVLASVR 317 + R K K LT + + R Sbjct: 294 NARRKLKGAILTTMLATR 311 >gi|26667199 calcium/calmodulin-dependent protein kinase II gamma isoform 3 [Homo sapiens] Length = 518 Score = 201 bits (511), Expect = 9e-52 Identities = 119/314 (37%), Positives = 177/314 (56%), Gaps = 31/314 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F ++Y+ E LG+G SVVRRC+ K ++QEYA K+I+ S + ++L +E Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + + +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR--EVCGTPSY 190 E + +H+ +IVHRDLKPEN+LL +KL DFG + +++ GE+ GTP Y Sbjct: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ-GEQQAWFGFAGTPGY 180 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG 250 L+PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F Sbjct: 181 LSPEVLR------KDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234 Query: 251 SPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHF 299 SPEWD + K+L+++ L + P R TA++AL HP+ +Q VE +R F Sbjct: 235 SPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKF 294 Query: 300 SPRGKFKVIALTVL 313 + R K K LT + Sbjct: 295 NARRKLKGAILTTM 308 >gi|26667191 calcium/calmodulin-dependent protein kinase II gamma isoform 4 [Homo sapiens] Length = 495 Score = 201 bits (511), Expect = 9e-52 Identities = 119/314 (37%), Positives = 177/314 (56%), Gaps = 31/314 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F ++Y+ E LG+G SVVRRC+ K ++QEYA K+I+ S + ++L +E Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + + +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR--EVCGTPSY 190 E + +H+ +IVHRDLKPEN+LL +KL DFG + +++ GE+ GTP Y Sbjct: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ-GEQQAWFGFAGTPGY 180 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG 250 L+PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F Sbjct: 181 LSPEVLR------KDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234 Query: 251 SPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHF 299 SPEWD + K+L+++ L + P R TA++AL HP+ +Q VE +R F Sbjct: 235 SPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKF 294 Query: 300 SPRGKFKVIALTVL 313 + R K K LT + Sbjct: 295 NARRKLKGAILTTM 308 >gi|26667211 calcium/calmodulin-dependent protein kinase II gamma isoform 6 [Homo sapiens] Length = 504 Score = 201 bits (511), Expect = 9e-52 Identities = 119/314 (37%), Positives = 177/314 (56%), Gaps = 31/314 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F ++Y+ E LG+G SVVRRC+ K ++QEYA K+I+ S + ++L +E Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + + +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR--EVCGTPSY 190 E + +H+ +IVHRDLKPEN+LL +KL DFG + +++ GE+ GTP Y Sbjct: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ-GEQQAWFGFAGTPGY 180 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG 250 L+PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F Sbjct: 181 LSPEVLR------KDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234 Query: 251 SPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHF 299 SPEWD + K+L+++ L + P R TA++AL HP+ +Q VE +R F Sbjct: 235 SPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKF 294 Query: 300 SPRGKFKVIALTVL 313 + R K K LT + Sbjct: 295 NARRKLKGAILTTM 308 >gi|26667203 calcium/calmodulin-dependent protein kinase II gamma isoform 1 [Homo sapiens] Length = 556 Score = 201 bits (511), Expect = 9e-52 Identities = 119/314 (37%), Positives = 177/314 (56%), Gaps = 31/314 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F ++Y+ E LG+G SVVRRC+ K ++QEYA K+I+ S + ++L +E Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + + +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR--EVCGTPSY 190 E + +H+ +IVHRDLKPEN+LL +KL DFG + +++ GE+ GTP Y Sbjct: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ-GEQQAWFGFAGTPGY 180 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG 250 L+PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F Sbjct: 181 LSPEVLR------KDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234 Query: 251 SPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHF 299 SPEWD + K+L+++ L + P R TA++AL HP+ +Q VE +R F Sbjct: 235 SPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKF 294 Query: 300 SPRGKFKVIALTVL 313 + R K K LT + Sbjct: 295 NARRKLKGAILTTM 308 >gi|26667196 calcium/calmodulin-dependent protein kinase II gamma isoform 2 [Homo sapiens] Length = 527 Score = 201 bits (511), Expect = 9e-52 Identities = 119/314 (37%), Positives = 177/314 (56%), Gaps = 31/314 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F ++Y+ E LG+G SVVRRC+ K ++QEYA K+I+ S + ++L +E Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + HPNI++L D+ F +LVFDL+ GELF+ + + SE + + +L Sbjct: 63 RICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR--EVCGTPSY 190 E + +H+ +IVHRDLKPEN+LL +KL DFG + +++ GE+ GTP Y Sbjct: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ-GEQQAWFGFAGTPGY 180 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG 250 L+PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F Sbjct: 181 LSPEVLR------KDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234 Query: 251 SPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHF 299 SPEWD + K+L+++ L + P R TA++AL HP+ +Q VE +R F Sbjct: 235 SPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKF 294 Query: 300 SPRGKFKVIALTVL 313 + R K K LT + Sbjct: 295 NARRKLKGAILTTM 308 >gi|149589021 doublecortin-like kinase 3 [Homo sapiens] Length = 648 Score = 198 bits (504), Expect = 6e-51 Identities = 109/283 (38%), Positives = 167/283 (59%), Gaps = 23/283 (8%) Query: 13 AQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATL 72 A + ++YE ++G G +VV+ C H+ T Q YA+K+ID + ++ + Sbjct: 349 AANVEKHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKS--------RLKGKEDMVD 400 Query: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMR 132 E+ I++ +S HPNI++L + YET+ +L+ + ++ G+LFD + E V E + ++ Sbjct: 401 SEILIIQSLS-HPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIM 459 Query: 133 ALLEVICTLHKLNIVHRDLKPENILL----DDNMNIKLTDFGFSCQLEPGERLREVCGTP 188 L + + +H +IVHRDLKPEN+L+ D + +KL DFG + + + VCGTP Sbjct: 460 DLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVV--RPIFTVCGTP 517 Query: 189 SYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFW--HRKQMLMLRMIMSGN 246 +Y+APEI+ GYG EVDMW+ GVI+Y LL G PPF R Q + +I G+ Sbjct: 518 TYVAPEIL------SEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGH 571 Query: 247 YQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQ 289 ++F P WD+ SD KDLVSR LVV P+ RYTA + L HP+ + Sbjct: 572 FEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIE 614 >gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo sapiens] Length = 370 Score = 197 bits (502), Expect = 1e-50 Identities = 107/284 (37%), Positives = 158/284 (55%), Gaps = 20/284 (7%) Query: 8 PDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVREL 67 P A+D + Y+ +++LG G S V K T + A+K I +E E Sbjct: 8 PRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCI---------AKEALEG 58 Query: 68 REATLK-EVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKE 126 +E +++ E+ +L K+ HPNI+ L D YE+ +L+ L+ GELFD + EK +E++ Sbjct: 59 KEGSMENEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERD 117 Query: 127 TRKIMRALLEVICTLHKLNIVHRDLKPENIL---LDDNMNIKLTDFGFSCQLEPGERLRE 183 +++ +L+ + LH L IVHRDLKPEN+L LD++ I ++DFG S +PG L Sbjct: 118 ASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLST 177 Query: 184 VCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIM 243 CGTP Y+APE++ Y K VD WS GVI Y LL G PPF+ + I+ Sbjct: 178 ACGTPGYVAPEVLA------QKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQIL 231 Query: 244 SGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF 287 Y+F SP WDD SD+ KD + + P+ R+T E+AL HP+ Sbjct: 232 KAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275 >gi|26051204 calcium/calmodulin-dependent protein kinase II beta isoform 1 [Homo sapiens] Length = 666 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26051210 calcium/calmodulin-dependent protein kinase II beta isoform 4 [Homo sapiens] Length = 517 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26051214 calcium/calmodulin-dependent protein kinase II beta isoform 6 [Homo sapiens] Length = 492 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26051206 calcium/calmodulin-dependent protein kinase II beta isoform 2 [Homo sapiens] Length = 542 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26051216 calcium/calmodulin-dependent protein kinase II beta isoform 7 [Homo sapiens] Length = 479 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26051218 calcium/calmodulin-dependent protein kinase II beta isoform 8 [Homo sapiens] Length = 449 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26051212 calcium/calmodulin-dependent protein kinase II beta isoform 5 [Homo sapiens] Length = 503 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|26051208 calcium/calmodulin-dependent protein kinase II beta isoform 3 [Homo sapiens] Length = 518 Score = 197 bits (500), Expect = 2e-50 Identities = 114/317 (35%), Positives = 172/317 (54%), Gaps = 29/317 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + Y+ E +G+G SVVRRC+ T EYA K+I+ S + ++L +E Sbjct: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTK---KLSARDHQKLE----REA 62 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 I R + H NI++L D+ F +LVFDL+ GELF+ + + SE + ++ +L Sbjct: 63 RICRLLK-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL 121 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSCQLEPGERLR-EVCGTPSYL 191 E + H++ +VHRDLKPEN+LL +KL DFG + +++ ++ GTP YL Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYL 181 Query: 192 APEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGS 251 +PE++ YGK VD+W+ GVI+Y LL G PPFW Q + + I +G Y F S Sbjct: 182 SPEVLR------KEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235 Query: 252 PEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF-----------FQQYLVEEVRHFS 300 PEWD + K+L+++ L + P R TA EAL HP+ +Q VE ++ F+ Sbjct: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFN 295 Query: 301 PRGKFKVIALTVLASVR 317 R K K LT + + R Sbjct: 296 ARRKLKGAILTTMLATR 312 >gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo sapiens] Length = 473 Score = 196 bits (499), Expect = 2e-50 Identities = 120/313 (38%), Positives = 173/313 (55%), Gaps = 33/313 (10%) Query: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79 +E + LGRG +S+V RC K T + YA+KV+ T ++ E+ +L Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVD-----------KKIVRTEIGVLL 94 Query: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139 ++S HPNII+LK+ +ET T LV +L+ GELFD + EK SE++ ++ +LE + Sbjct: 95 RLS-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVA 153 Query: 140 TLHKLNIVHRDLKPENILL---DDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEII 196 LH+ IVHRDLKPEN+L + +K+ DFG S +E ++ VCGTP Y APEI+ Sbjct: 154 YLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEIL 213 Query: 197 E-CSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFW-HRKQMLMLRMIMSGNYQFGSPEW 254 C+ YG EVDMWS G+I Y LL G PF+ R M R I++ Y F SP W Sbjct: 214 RGCA-------YGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWW 266 Query: 255 DDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF---------FQQYLVEEVRHFSPRGKF 305 D+ S KDLV + +V+ P+ R T +AL HP+ ++++ F+ R K Sbjct: 267 DEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKL 326 Query: 306 KVIALTVLASVRI 318 K V+AS R+ Sbjct: 327 KAAVKAVVASSRL 339 >gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1 [Homo sapiens] Length = 357 Score = 196 bits (498), Expect = 3e-50 Identities = 107/279 (38%), Positives = 156/279 (55%), Gaps = 20/279 (7%) Query: 13 AQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATL 72 A+D + +E KE LG G S V K T + +AVK I P++ + +E+++ Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCI---------PKKALKGKESSI 66 Query: 73 K-EVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIM 131 + E+ +LRK+ H NI+ L+D YE+ +LV L+ GELFD + EK +EK+ ++ Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125 Query: 132 RALLEVICTLHKLNIVHRDLKPENILL---DDNMNIKLTDFGFSCQLEPGERLREVCGTP 188 R +L+ + LH++ IVHRDLKPEN+L D+ I ++DFG S G+ + CGTP Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTP 185 Query: 189 SYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQ 248 Y+APE++ Y K VD WS GVI Y LL G PPF+ + I+ Y+ Sbjct: 186 GYVAPEVLA------QKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239 Query: 249 FGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF 287 F SP WDD SD+ KD + + P RYT E+A HP+ Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPW 278 >gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2 [Homo sapiens] Length = 385 Score = 196 bits (498), Expect = 3e-50 Identities = 107/279 (38%), Positives = 156/279 (55%), Gaps = 20/279 (7%) Query: 13 AQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATL 72 A+D + +E KE LG G S V K T + +AVK I P++ + +E+++ Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCI---------PKKALKGKESSI 66 Query: 73 K-EVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIM 131 + E+ +LRK+ H NI+ L+D YE+ +LV L+ GELFD + EK +EK+ ++ Sbjct: 67 ENEIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125 Query: 132 RALLEVICTLHKLNIVHRDLKPENILL---DDNMNIKLTDFGFSCQLEPGERLREVCGTP 188 R +L+ + LH++ IVHRDLKPEN+L D+ I ++DFG S G+ + CGTP Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTP 185 Query: 189 SYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQ 248 Y+APE++ Y K VD WS GVI Y LL G PPF+ + I+ Y+ Sbjct: 186 GYVAPEVLA------QKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239 Query: 249 FGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF 287 F SP WDD SD+ KD + + P RYT E+A HP+ Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPW 278 >gi|4557511 death-associated protein kinase 3 [Homo sapiens] Length = 454 Score = 186 bits (473), Expect = 2e-47 Identities = 110/288 (38%), Positives = 158/288 (54%), Gaps = 14/288 (4%) Query: 14 QDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLK 73 +D ++YE E LG G ++VR+C K T +EYA K I S RE + Sbjct: 7 EDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKR---RLSSSRRGVSREEIER 63 Query: 74 EVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133 EV+ILR++ HPNII L D +E T L+ +L+ GELFD+L EK +L+E E + ++ Sbjct: 64 EVNILREIR-HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQ 122 Query: 134 LLEVICTLHKLNIVHRDLKPENILLDD----NMNIKLTDFGFSCQLEPGERLREVCGTPS 189 +L+ + LH I H DLKPENI+L D N IKL DFG + ++E G + + GTP Sbjct: 123 ILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPE 182 Query: 190 YLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQF 249 ++APEI+ ++ G E DMWS GVI Y LL+G+ PF + L I + NY F Sbjct: 183 FVAPEIV------NYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDF 236 Query: 250 GSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVR 297 + + S+ KD + R LV P+ R T ++L H + + VR Sbjct: 237 DEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVR 284 >gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2 isoform b [Homo sapiens] Length = 741 Score = 186 bits (473), Expect = 2e-47 Identities = 107/280 (38%), Positives = 152/280 (54%), Gaps = 27/280 (9%) Query: 16 FYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75 F + YE KE +G G SV +RC+HK T EYAVK+ID + + +E+ Sbjct: 419 FTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS-------------KRDPSEEI 465 Query: 76 DILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALL 135 +IL + HPNII LKD Y+ F +LV +LM+ GEL D + + SE+E ++ + Sbjct: 466 EILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTIT 525 Query: 136 EVICTLHKLNIVHRDLKPENILLDDNM----NIKLTDFGFSCQLEPGE-RLREVCGTPSY 190 + + LH +VHRDLKP NIL D +I++ DFGF+ QL G L C T ++ Sbjct: 526 KTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 585 Query: 191 LAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQML---MLRMIMSGNY 247 +APE+++ GY D+WS G+++YT+LAG PF + +L I SG Y Sbjct: 586 VAPEVLK------RQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKY 639 Query: 248 QFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPF 287 WD SD KD+VS+ L V P R TA + L HP+ Sbjct: 640 ALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPW 679 Score = 134 bits (336), Expect = 2e-31 Identities = 93/293 (31%), Positives = 156/293 (53%), Gaps = 32/293 (10%) Query: 10 SHSAQDFYENYEPKE-----ILGRGVSS---VVRRCIHKPTSQEYAVKVIDVTGGGSFSP 61 SH ++ +E +P + +LG+G +VR+ Q YA+KV+ + Sbjct: 52 SHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKK------AT 105 Query: 62 EEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVT 121 +VR+ R + E DIL +V+ HP I++L ++T +L+ D ++ G+LF L+++V Sbjct: 106 LKVRD-RVRSKMERDILAEVN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM 163 Query: 122 LSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQ-LEPGER 180 +E++ + + L + LH L I++RDLKPENILLD+ +IK+TDFG S + ++ +R Sbjct: 164 FTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKR 223 Query: 181 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR 240 CGT Y+APE++ + G+ + D WS GV+M+ +L GS PF + + + Sbjct: 224 AYSFCGTIEYMAPEVV------NRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMA 277 Query: 241 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTA-----EEALAHPFF 288 +I+ + G P++ S + L+ P NR A EE HPFF Sbjct: 278 LILKA--KLGMPQF--LSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 326 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,051,753 Number of Sequences: 37866 Number of extensions: 684255 Number of successful extensions: 3714 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 719 Number of HSP's successfully gapped in prelim test: 85 Number of HSP's that attempted gapping in prelim test: 1290 Number of HSP's gapped (non-prelim): 990 length of query: 387 length of database: 18,247,518 effective HSP length: 104 effective length of query: 283 effective length of database: 14,309,454 effective search space: 4049575482 effective search space used: 4049575482 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.