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Search of human proteins with 5453579
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453579 bone morphogenetic protein 1 isoform 3 precursor
[Homo sapiens]
(986 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 2090 0.0
gi|6912724 tolloid-like 2 [Homo sapiens] 1600 0.0
gi|22547221 tolloid-like 1 [Homo sapiens] 1583 0.0
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 1487 0.0
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 1484 0.0
gi|126091152 cubilin [Homo sapiens] 328 2e-89
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 228 2e-59
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 217 4e-56
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 199 8e-51
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 199 1e-50
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 199 1e-50
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 199 1e-50
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H... 172 1e-42
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 172 1e-42
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 172 1e-42
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 164 4e-40
gi|13899255 membrane frizzled-related protein [Homo sapiens] 155 2e-37
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 152 1e-36
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 150 6e-36
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 150 6e-36
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 150 6e-36
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 150 6e-36
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 150 6e-36
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 150 6e-36
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 148 3e-35
gi|66347875 complement component 1, r subcomponent [Homo sapiens] 142 1e-33
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 139 1e-32
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 139 1e-32
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 139 1e-32
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 138 2e-32
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 2090 bits (5416), Expect = 0.0
Identities = 986/986 (100%), Positives = 986/986 (100%)
Query: 1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE 60
MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE
Sbjct: 1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE 60
Query: 61 EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR 120
EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR
Sbjct: 61 EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR 120
Query: 121 AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY 180
AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY
Sbjct: 121 AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY 180
Query: 181 RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN 240
RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN
Sbjct: 181 RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN 240
Query: 241 IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG 300
IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG
Sbjct: 241 IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG 300
Query: 301 QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI 360
QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI
Sbjct: 301 QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI 360
Query: 361 ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS 420
ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS
Sbjct: 361 ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS 420
Query: 421 NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF 480
NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF
Sbjct: 421 NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF 480
Query: 481 EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF 540
EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF
Sbjct: 481 EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF 540
Query: 541 AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG 600
AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG
Sbjct: 541 AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG 600
Query: 601 SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK 660
SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK
Sbjct: 601 SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK 660
Query: 661 LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN 720
LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN
Sbjct: 661 LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN 720
Query: 721 TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST 780
TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST
Sbjct: 721 TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST 780
Query: 781 PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR 840
PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR
Sbjct: 781 PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR 840
Query: 841 FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY 900
FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY
Sbjct: 841 FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY 900
Query: 901 GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS 960
GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS
Sbjct: 901 GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS 960
Query: 961 DDTITKKGFHLRYTSTKFQDTLHSRK 986
DDTITKKGFHLRYTSTKFQDTLHSRK
Sbjct: 961 DDTITKKGFHLRYTSTKFQDTLHSRK 986
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 1600 bits (4144), Expect = 0.0
Identities = 744/1015 (73%), Positives = 850/1015 (83%), Gaps = 29/1015 (2%)
Query: 1 MPGVARLPLLLGLLLL---PRPG-----RPLDLADYTYDLAEEDDSEPL-NYKDPCKAAA 51
MP L L+ LLLL PR RP ADY+ EE + L +Y DPCKAA
Sbjct: 1 MPRATALGALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGTEQQLEHYHDPCKAAV 60
Query: 52 FLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTN----GQPQRG 107
F GDIALDE+DL+ F + +A D + T + ++ S T G + G
Sbjct: 61 FWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG 120
Query: 108 ACGRWRGR----------------SRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVF 151
GR R RRA TSR ER+WP GVIP+VIGGNFTGSQRA+F
Sbjct: 121 KDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIF 180
Query: 152 RQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIV 211
+QAMRHWEKHTCVTF+ERTDE+S+IVF+YR CGCCSYVGRRGGGPQAISIGKNCDKFGIV
Sbjct: 181 KQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIV 240
Query: 212 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH 271
HELGHVVGFWHEHTRPDRD+HV+I+RENIQPGQEYNFLKME EV SLGETYDFDSIMH
Sbjct: 241 AHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMH 300
Query: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTG 331
YARNTFSRG+FLDTI+P+ + NGV+P IGQR RLS+GDIAQARKLYKCPACGETLQD+TG
Sbjct: 301 YARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTG 360
Query: 332 NFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAP 391
NFS+P +PNGY ++ HCVWRISVTPGEKI+LNFTS+DL++SRLCWYDYVEVRDG+WRKAP
Sbjct: 361 NFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAP 420
Query: 392 LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNY 451
L GRFCG K+PEP+VSTDSRLWVEFRSSSN +GKGFFA YEA CGGD+ KD G IQSPNY
Sbjct: 421 LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNKDAGQIQSPNY 480
Query: 452 PDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCG 511
PDDYRPSK C+WRI VSEGFHVGLTFQ+FEIERHDSCAYDYLEVRDG +E S LIG +CG
Sbjct: 481 PDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCG 540
Query: 512 YEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYK 571
YEKP+D+KS+S+RLW+KFVSDGSINKAGFA NFFKEVDECS P+ GGCE RC+NTLGSYK
Sbjct: 541 YEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYK 600
Query: 572 CSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISL 631
C+CDPGYELA DK+ CE ACGGF+TKLNG+ITSPGWPKEYP NKNC+WQ+VAP QYRISL
Sbjct: 601 CACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISL 660
Query: 632 QFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTV 691
QF+ FE EGNDVCKYDFVEVRSGL+ D+KLHG+FCGSE PEVITSQ NNMRVEFKSDNTV
Sbjct: 661 QFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTV 720
Query: 692 SKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKV 751
SK+GF+AHFFSDKDEC+KDNGGCQ +CVNTFGSY C+CR+G+ LH+N HDCKEAGC HK+
Sbjct: 721 SKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKI 780
Query: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
+S GT+ SPNWPDKYPS++ECTW ISST GHRVKLTF E +IE ECAYDHLE++DG
Sbjct: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
Query: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTK 871
D+ AP+LGRFCGSKKP+P +A+GS MFLRFYSD SVQRKGFQA H+TECGG+++A+V+TK
Sbjct: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTK 900
Query: 872 DLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDST 931
+LYSHAQFGDNNYP C+WVIVAE+GYGVEL F+TFEVEEE DCGYDYME +DGYDS+
Sbjct: 901 ELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSS 960
Query: 932 APRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK 986
APRLGR+CGSGP EE+YSAGDS++++F +DDTI KKGFH RYTSTKFQD LH +K
Sbjct: 961 APRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQDALHMKK 1015
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 1583 bits (4098), Expect = 0.0
Identities = 713/980 (72%), Positives = 842/980 (85%), Gaps = 20/980 (2%)
Query: 27 DYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAVDLRR-------HTA 79
DYT+D EED +E ++YKDPCKAA F GDIALD+EDL FQ+ + +DL + HT
Sbjct: 34 DYTFDGNEEDKTETIDYKDPCKAAVFWGDIALDDEDLNIFQIDRTIDLTQNPFGNLGHTT 93
Query: 80 ----------RKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRG---RSRSRRAATSRP 126
++ ++ + N + ++ G ++R RAATSR
Sbjct: 94 GGLGDHAMSKKRGALYQLIDRIRRIGFGLEQNNTVKGKVPLQFSGQNEKNRVPRAATSRT 153
Query: 127 ERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCC 186
ER+WP GVIP+VIGGNFTGSQRA+F+QAMRHWEKHTCVTF+ER+DE+SYIVFTYRPCGCC
Sbjct: 154 ERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSDEESYIVFTYRPCGCC 213
Query: 187 SYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQE 246
SYVGRRG GPQAISIGKNCDKFGIVVHELGHV+GFWHEHTRPDRD HV+I+RENIQPGQE
Sbjct: 214 SYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQE 273
Query: 247 YNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLS 306
YNFLKMEP EV SLGE YDFDSIMHYARNTFSRG+FLDTI+P + NG++P IGQRTRLS
Sbjct: 274 YNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLS 333
Query: 307 KGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS 366
KGDIAQARKLY+CPACGETLQ+S GN SSP +PNGY ++ HC+WR+SVTPGEKI+LNFT+
Sbjct: 334 KGDIAQARKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTT 393
Query: 367 LDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKG 426
+DLY+S LCWYDY+EVRDG+WRK+PL GRFCG KLPE + STDSR+W+EFRSSSNWVGKG
Sbjct: 394 MDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKG 453
Query: 427 FFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD 486
F AVYEAICGG+++K+ G IQSPNYPDDYRP K C+W+I VSE +HVGLTFQSFEIERHD
Sbjct: 454 FAAVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHD 513
Query: 487 SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546
+CAYDYLEVRDG SE+S LIGR+CGY+KP+DI+STS+ LW+KFVSDG++NKAGFA NFFK
Sbjct: 514 NCAYDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK 573
Query: 547 EVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPG 606
E DEC++P+RGGCEQRCLNTLGSY+C+C+PGYEL PD+R CEAACGG LTKLNG+IT+PG
Sbjct: 574 EEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPG 633
Query: 607 WPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFC 666
WPKEYPPNKNC+WQ+VAPTQYRIS++F+FFE EGN+VCKYD+VE+ SGL+++SKLHGKFC
Sbjct: 634 WPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFC 693
Query: 667 GSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYE 726
G+E PEVITSQ+NNMR+EFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQ +CVNT GSY
Sbjct: 694 GAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYM 753
Query: 727 CQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVK 786
CQCR+GFVLHDNKHDCKEA C+ K+ S SG ITSPNWPDKYPS+KECTW IS+TPGHR+K
Sbjct: 754 CQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIK 813
Query: 787 LTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNS 846
L F E +IE ECAYDHLEVFDG K+P+LGR CG+K P+P++ATG++MF+RF SD S
Sbjct: 814 LAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDAS 873
Query: 847 VQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVF 906
VQRKGFQA+H+TECGG+++A+ K +DLYSHAQFGDNNYPG VDCEW++V+E G +EL F
Sbjct: 874 VQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSF 933
Query: 907 QTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITK 966
QTFEVEEE DCGYDY+ELFDG DSTA LGR+CGSGPPEE+YS GDSVL+ FH+DDTI K
Sbjct: 934 QTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINK 993
Query: 967 KGFHLRYTSTKFQDTLHSRK 986
KGFH+RY S ++ DT H++K
Sbjct: 994 KGFHIRYKSIRYPDTTHTKK 1013
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 1487 bits (3849), Expect = 0.0
Identities = 703/704 (99%), Positives = 704/704 (100%)
Query: 1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE 60
MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE
Sbjct: 1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE 60
Query: 61 EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR 120
EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR
Sbjct: 61 EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR 120
Query: 121 AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY 180
AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY
Sbjct: 121 AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY 180
Query: 181 RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN 240
RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN
Sbjct: 181 RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN 240
Query: 241 IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG 300
IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG
Sbjct: 241 IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG 300
Query: 301 QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI 360
QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI
Sbjct: 301 QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI 360
Query: 361 ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS 420
ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS
Sbjct: 361 ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS 420
Query: 421 NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF 480
NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF
Sbjct: 421 NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF 480
Query: 481 EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF 540
EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF
Sbjct: 481 EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF 540
Query: 541 AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG 600
AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG
Sbjct: 541 AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG 600
Query: 601 SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK 660
SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK
Sbjct: 601 SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK 660
Query: 661 LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDK 704
LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS+K
Sbjct: 661 LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEK 704
Score = 308 bits (788), Expect = 2e-83
Identities = 161/427 (37%), Positives = 231/427 (54%), Gaps = 47/427 (11%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CG ++ G+ SP YP+ Y C+WRI V+ G + L F S ++ R C YDY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGS-INKAGFAVNFFKEVDECSR 553
VRDG + L GR+CG + P+ I ST SRLW++F S + + K FAV
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY---------- 431
Query: 554 PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPP 613
EA CGG + K G I SP +P +Y P
Sbjct: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
Query: 614 NKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV 673
+K CIW++ + + L F FE E +D C YD++EVR G + S L G++CG EKP+
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDN-GGCQQDCVNTFGSYECQCRSG 732
I S + + ++F SD +++K GF +FF + DECS+ N GGC+Q C+NT GSY+C C G
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPG 577
Query: 733 FVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEM 792
+ L +K C EA C +T +G+ITSP WP +YP K C W + + +R+ L F
Sbjct: 578 YELAPDKRRC-EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFF 636
Query: 793 DIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
+ E C YD +EV G A + + G+FCGS+KPE + + + M + F SDN+V +KGF
Sbjct: 637 ETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Query: 853 QASHATE 859
+A +E
Sbjct: 697 KAHFFSE 703
Score = 208 bits (529), Expect = 2e-53
Identities = 127/427 (29%), Positives = 189/427 (44%), Gaps = 82/427 (19%)
Query: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
ACG L G+ +SP +P Y + +C+W++ +I L F + + +C YD+V
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSK 709
EVR G + L G+FCGS+ PE I S + + VEF+S + KGF A +
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY--------- 431
Query: 710 DNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPS 769
EA C V G I SPN+PD Y
Sbjct: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
Query: 770 KKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEP 829
K C W I + G V LTF +IE CAYD+LEV DG + ++GR+CG +KP+
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 830 VLATGSRMFLRFYSDNSVQRKGFQAS---HATECGGQVRADVKTKDLYSHAQFG------ 880
+ +T SR++L+F SD S+ + GF + EC R + + L + +
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPG 577
Query: 881 ------------------------------DNNYPGGVDCEWVIVAEEGYGVELVFQTFE 910
YP +C W +VA Y + L F FE
Sbjct: 578 YELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFE 637
Query: 911 VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFH 970
E C YD++E+ G + + G++CGS PE + S +++ V+F SD+T++KKGF
Sbjct: 638 TEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 971 LRYTSTK 977
+ S K
Sbjct: 698 AHFFSEK 704
Score = 177 bits (449), Expect = 4e-44
Identities = 98/280 (35%), Positives = 140/280 (50%), Gaps = 45/280 (16%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG ++ G+ SP YP+ Y C+WRI V+ G + L F S ++ R C YDY+E
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY---------- 431
VRDG + L GR+CG + P+ I ST SRLW++F S + + K FAV
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGS-INKAGFAVNFFKEVDECSR 553
Query: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
EA CGG + K G I SP +P +Y P
Sbjct: 554 PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPP 613
Query: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
+K CIW++ + + L F FE E +D C YD++EVR G + S L G++CG EKP+
Sbjct: 614 NKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV 673
Query: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRG 557
I S + + ++F SD +++K GF +FF E +P RG
Sbjct: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQPPRG 713
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 1484 bits (3842), Expect = 0.0
Identities = 702/702 (100%), Positives = 702/702 (100%)
Query: 1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE 60
MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE
Sbjct: 1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE 60
Query: 61 EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR 120
EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR
Sbjct: 61 EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR 120
Query: 121 AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY 180
AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY
Sbjct: 121 AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY 180
Query: 181 RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN 240
RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN
Sbjct: 181 RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN 240
Query: 241 IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG 300
IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG
Sbjct: 241 IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG 300
Query: 301 QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI 360
QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI
Sbjct: 301 QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI 360
Query: 361 ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS 420
ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS
Sbjct: 361 ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS 420
Query: 421 NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF 480
NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF
Sbjct: 421 NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF 480
Query: 481 EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF 540
EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF
Sbjct: 481 EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF 540
Query: 541 AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG 600
AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG
Sbjct: 541 AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG 600
Query: 601 SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK 660
SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK
Sbjct: 601 SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK 660
Query: 661 LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS
Sbjct: 661 LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 307 bits (786), Expect = 4e-83
Identities = 160/422 (37%), Positives = 229/422 (54%), Gaps = 47/422 (11%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CG ++ G+ SP YP+ Y C+WRI V+ G + L F S ++ R C YDY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGS-INKAGFAVNFFKEVDECSR 553
VRDG + L GR+CG + P+ I ST SRLW++F S + + K FAV
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY---------- 431
Query: 554 PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPP 613
EA CGG + K G I SP +P +Y P
Sbjct: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
Query: 614 NKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV 673
+K CIW++ + + L F FE E +D C YD++EVR G + S L G++CG EKP+
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDN-GGCQQDCVNTFGSYECQCRSG 732
I S + + ++F SD +++K GF +FF + DECS+ N GGC+Q C+NT GSY+C C G
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPG 577
Query: 733 FVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEM 792
+ L +K C EA C +T +G+ITSP WP +YP K C W + + +R+ L F
Sbjct: 578 YELAPDKRRC-EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFF 636
Query: 793 DIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
+ E C YD +EV G A + + G+FCGS+KPE + + + M + F SDN+V +KGF
Sbjct: 637 ETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Query: 853 QA 854
+A
Sbjct: 697 KA 698
Score = 206 bits (525), Expect = 7e-53
Identities = 126/425 (29%), Positives = 188/425 (44%), Gaps = 82/425 (19%)
Query: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
ACG L G+ +SP +P Y + +C+W++ +I L F + + +C YD+V
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSK 709
EVR G + L G+FCGS+ PE I S + + VEF+S + KGF A +
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY--------- 431
Query: 710 DNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPS 769
EA C V G I SPN+PD Y
Sbjct: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
Query: 770 KKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEP 829
K C W I + G V LTF +IE CAYD+LEV DG + ++GR+CG +KP+
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 830 VLATGSRMFLRFYSDNSVQRKGFQAS---HATECGGQVRADVKTKDLYSHAQF------- 879
+ +T SR++L+F SD S+ + GF + EC R + + L + +
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPG 577
Query: 880 -----------------------------GDNNYPGGVDCEWVIVAEEGYGVELVFQTFE 910
YP +C W +VA Y + L F FE
Sbjct: 578 YELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFE 637
Query: 911 VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFH 970
E C YD++E+ G + + G++CGS PE + S +++ V+F SD+T++KKGF
Sbjct: 638 TEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 971 LRYTS 975
+ S
Sbjct: 698 AHFFS 702
Score = 172 bits (435), Expect = 2e-42
Identities = 94/272 (34%), Positives = 137/272 (50%), Gaps = 45/272 (16%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG ++ G+ SP YP+ Y C+WRI V+ G + L F S ++ R C YDY+E
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY---------- 431
VRDG + L GR+CG + P+ I ST SRLW++F S + + K FAV
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGS-INKAGFAVNFFKEVDECSR 553
Query: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
EA CGG + K G I SP +P +Y P
Sbjct: 554 PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPP 613
Query: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
+K CIW++ + + L F FE E +D C YD++EVR G + S L G++CG EKP+
Sbjct: 614 NKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV 673
Query: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVD 549
I S + + ++F SD +++K GF +FF ++
Sbjct: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHFFSVLE 705
Score = 81.6 bits (200), Expect = 3e-15
Identities = 41/117 (35%), Positives = 64/117 (54%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACG L G+ +SP +P Y + +C+W++ +I L F + + +C YD+V
Sbjct: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
EVR G + L G+FCGS+ PE I S + + VEF+S + KGF A + ++ G
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVLEG 706
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 328 bits (840), Expect = 2e-89
Identities = 217/735 (29%), Positives = 329/735 (44%), Gaps = 126/735 (17%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY-DY 379
AC + D G F+SP +PN Y + C++RI+V G+ I ++FT+ L + +Y D+
Sbjct: 1047 ACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDF 1106
Query: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI---CG 436
+E+RDG + K+PL G F GS LP I+S ++LW++F+S GF A ++ CG
Sbjct: 1107 LEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTGCG 1166
Query: 437 GDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVR 496
G++ G SPNYP Y S C W ++ S G L F+ F +E H +C DYL V
Sbjct: 1167 GNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVY 1226
Query: 497 DGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF------------ 544
DG S +S L+ + CG EKP I+S+ +++K +D GF +
Sbjct: 1227 DGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYRQTCENVVIVNQ 1286
Query: 545 -FKEVDECSRPNRGGCEQRCLNTLGS----------------YKCSCDPGY-ELAPDKRR 586
+ ++ PN Q C T+ + + +C Y EL R+
Sbjct: 1287 TYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ 1346
Query: 587 CEAACG----------------------------GF------------LTKLNGSITSPG 606
CG GF L+ GS +SPG
Sbjct: 1347 MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGATGSFSSPG 1406
Query: 607 WPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFC 666
+P YPPNK CIW + I L F+ E + C +D +E+ G S + C
Sbjct: 1407 FPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLC 1466
Query: 667 GSEKPE---VITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFG 723
PE ++S N + + FK+D +++ +GF A +
Sbjct: 1467 TQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASW----------------------- 1503
Query: 724 SYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGH 783
Q +G GC + SG I SPN+P Y S +C+W I H
Sbjct: 1504 ----QAVTG-------------GCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNH 1546
Query: 784 RVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKK-PEPVLATGSRMFLRFY 842
RV L F + D+E Q C + +DG + L R CG ++ P++++G+ +FLRF
Sbjct: 1547 RVLLNFTDFDLEPQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQ 1602
Query: 843 SDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYG- 901
S S Q +GF+A CGG + + D S +F NYP +C W+I A+
Sbjct: 1603 SGPSRQNRGFRAQFRQACGGHIL--TSSFDTVSSPRF-PANYPNNQNCSWIIQAQPPLNH 1659
Query: 902 VELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSD 961
+ L F FE+E T C D++E+ DG AP GRYCG+ P + S ++ ++F SD
Sbjct: 1660 ITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSD 1719
Query: 962 DTITKKGFHLRYTST 976
+I+ GFH T++
Sbjct: 1720 SSISAGGFHTTVTAS 1734
Score = 311 bits (798), Expect = 1e-84
Identities = 210/686 (30%), Positives = 323/686 (47%), Gaps = 96/686 (13%)
Query: 303 TRLSKGDIAQARKLYKCPACG-ETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPG-EKI 360
+R ++G AQ R+ ACG L S SSP +P Y + +C W I P I
Sbjct: 1606 SRQNRGFRAQFRQ-----ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHI 1660
Query: 361 ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS 420
L+FT +L RS C D+VE+ DG APLRGR+CG+ +P PI S S L + F S S
Sbjct: 1661 TLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDS 1720
Query: 421 NWVGKGFFAVYEA---ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF 477
+ GF A CGG G SP YPD Y P+ C+W I S G + L+F
Sbjct: 1721 SISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSF 1780
Query: 478 QSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKS-TSSRLWLKFVSDGSIN 536
SF++E C+ D++E+R+G++ + L+GRYCG P + S LW++F+SDGS +
Sbjct: 1781 ISFQLEDSQDCSRDFVEIREGNA-TGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGS 1839
Query: 537 KAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLT 596
GF F K N +G++
Sbjct: 1840 GTGFQATFMKIFGND-------------NIVGTH-------------------------- 1860
Query: 597 KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLT 656
G + SP WP+ YP N N W + + + + + E C YD + + G +
Sbjct: 1861 ---GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPS 1917
Query: 657 ADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQ 716
++L G +CG++ E +S N++ F SD+++S KGF +F+
Sbjct: 1918 IHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGFLLEWFA---------VDAPD 1967
Query: 717 DCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWA 776
+ T C GF+ + + SP WPD Y ++ +CTW
Sbjct: 1968 GVLPTIAPGAC---GGFL---------------RTGDAPVFLFSPGWPDSYSNRVDCTWL 2009
Query: 777 ISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSR 836
I + P V+L + +DIES CAYD L + DG + A L CG + P P+ +TG
Sbjct: 2010 IQA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEY 2068
Query: 837 MFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVA 896
MF+RF SD+SV R GF AS CGG + AD + + + ++ + YP ++C W ++
Sbjct: 2069 MFIRFTSDSSVTRAGFNASFHKSCGGYLHAD---RGIITSPKYPE-TYPSNLNCSWHVLV 2124
Query: 897 EEGYGVELVF-QTFEVEE-ETDCGY-DYMELFDGYDSTAPRL------GRYCGSGPPEEV 947
+ G + + F Q F++ ++ C DY+ L +G D +P L G +CGS +
Sbjct: 2125 QSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTL 2184
Query: 948 YSAGDSVLVKFHSDDTITKKGFHLRY 973
+++ + + V+F SD + +GF ++Y
Sbjct: 2185 FTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 310 bits (794), Expect = 4e-84
Identities = 206/670 (30%), Positives = 302/670 (45%), Gaps = 109/670 (16%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG Q +G SP YP+ Y ++ C W I V +++LNFT DL C Y
Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMAY-- 1567
Query: 382 VRDGFWRKAPLRGRFCG-SKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV- 439
DG R CG +L PIVS+ + L++ F+S + +GF A + CGG +
Sbjct: 1568 --DGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGHIL 1625
Query: 440 KKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGF-HVGLTFQSFEIERHDSCAYDYLEVRDG 498
+ + SP +P +Y ++ C W IQ H+ L+F FE+ER +CA D++E+ DG
Sbjct: 1626 TSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDG 1685
Query: 499 HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558
E + L GRYCG + P I S SS L L+FVSD SI+ GF V
Sbjct: 1686 GHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASV---------- 1735
Query: 559 CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCI 618
+ACGG G SPG+P YPPN C+
Sbjct: 1736 ------------------------------SACGGTFYMAEGIFNSPGYPDIYPPNVECV 1765
Query: 619 WQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQY 678
W +V+ R+ L F F+ E + C DFVE+R G A L G++CG+ P +S
Sbjct: 1766 WNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIV 1824
Query: 679 -NNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHD 737
+ + V F SD + S GF+A F + FG +D
Sbjct: 1825 GHTLWVRFISDGSGSGTGFQATF------------------MKIFG------------ND 1854
Query: 738 NKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQ 797
N + T G + SP WP+ YP W ++ H V +EMDIE
Sbjct: 1855 N------------IVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEI 1902
Query: 798 PECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQ---- 853
C YD L ++DG A ++G +CG+ + E +TG+ + FYSD+S+ KGF
Sbjct: 1903 QNCYYDKLRIYDGPSIHARLIGAYCGT-QTESFSSTGNSLTFHFYSDSSISGKGFLLEWF 1961
Query: 854 ASHATE----------CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVE 903
A A + CGG +R L+S ++Y VDC W+I A + VE
Sbjct: 1962 AVDAPDGVLPTIAPGACGGFLRTGDAPVFLFSPG--WPDSYSNRVDCTWLIQAPDS-TVE 2018
Query: 904 LVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDT 963
L + ++E C YD + + DG ++ A +L CG P + S G+ + ++F SD +
Sbjct: 2019 LNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSS 2078
Query: 964 ITKKGFHLRY 973
+T+ GF+ +
Sbjct: 2079 VTRAGFNASF 2088
Score = 290 bits (742), Expect = 5e-78
Identities = 200/669 (29%), Positives = 300/669 (44%), Gaps = 102/669 (15%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L +TG+FSSP +PN Y + C+W I PG I L D+ C +D +E
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLE 1450
Query: 382 VRDGFWRKAPLRGRFCGSKLPE---PIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI---C 435
+ G +P + C + PE + ST + L + F++ + G+GF A ++A+ C
Sbjct: 1451 IYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGC 1510
Query: 436 GGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEV 495
GG + G I SPNYP YR + C W I+V V L F F++E DSC Y
Sbjct: 1511 GGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMAY--- 1567
Query: 496 RDGHSESSTLIGRYCGYEK-PDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
DG S + + + R CG E+ + I S+ + L+L+F S S GF F
Sbjct: 1568 -DGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF---------- 1616
Query: 555 NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGG-FLTKLNGSITSPGWPKEYPP 613
ACGG LT +++SP +P YP
Sbjct: 1617 ---------------------------------RQACGGHILTSSFDTVSSPRFPANYPN 1643
Query: 614 NKNCIWQLVA-PTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPE 672
N+NC W + A P I+L F FE E + C DFVE+ G D+ L G++CG++ P
Sbjct: 1644 NQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPH 1703
Query: 673 VITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSG 732
ITS + + + F SD+++S GF + C GG TF E
Sbjct: 1704 PITSFSSALTLRFVSDSSISAGGFHTTVTASVSAC----GG-------TFYMAE------ 1746
Query: 733 FVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEM 792
G SP +PD YP EC W I S+PG+R++L+F+
Sbjct: 1747 -----------------------GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISF 1783
Query: 793 DIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLA-TGSRMFLRFYSDNSVQRKG 851
+E +C+ D +E+ +G +A ++GR+CG+ P + G +++RF SD S G
Sbjct: 1784 QLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTG 1842
Query: 852 FQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEV 911
FQA+ G K + F NYP + +W + + V ++
Sbjct: 1843 FQATFMKIFGNDNIVGTHGKVA---SPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDI 1899
Query: 912 EEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHL 971
EE +C YD + ++DG A +G YCG+ E S G+S+ F+SD +I+ KGF L
Sbjct: 1900 EEIQNCYYDKLRIYDGPSIHARLIGAYCGT-QTESFSSTGNSLTFHFYSDSSISGKGFLL 1958
Query: 972 RYTSTKFQD 980
+ + D
Sbjct: 1959 EWFAVDAPD 1967
Score = 290 bits (741), Expect = 6e-78
Identities = 197/661 (29%), Positives = 300/661 (45%), Gaps = 102/661 (15%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACGE L +STG SP +PN Y ++C W I V P I L F + L C DY+
Sbjct: 931 ACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYL 990
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-----C 435
EV D + GR+CG +P + S+ + L + F + S+ +GF YEAI C
Sbjct: 991 EVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAISAATAC 1048
Query: 436 GGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY-DYLE 494
D D G SPN+P++Y + CI+RI V G + + F +F +E Y D+LE
Sbjct: 1049 LQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLE 1108
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
+RDG E S L+G + G P I S S++LWLKF SD ++GF+ +
Sbjct: 1109 IRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWD--------- 1159
Query: 555 NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPN 614
GS CGG LT +G+ SP +P Y +
Sbjct: 1160 -------------GS------------------STGCGGNLTTSSGTFISPNYPMPYYHS 1188
Query: 615 KNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVI 674
C W L + L+F F E + C D++ V G +++S L + CG EKP +I
Sbjct: 1189 SECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLI 1248
Query: 675 TSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFV 734
S ++M ++ ++D +GFKA + +Q C N
Sbjct: 1249 RSSGDSMFIKLRTDEGQQGRGFKAEY--------------RQTCENVV------------ 1282
Query: 735 LHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDI 794
V T G + S +P+ Y + C W I +T G+ V TF+ D+
Sbjct: 1283 ---------------IVNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDL 1327
Query: 795 ESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR-KGFQ 853
E C+ D+LE++DG +GR+CG P P T S++ + +D +R KGFQ
Sbjct: 1328 EHHINCSTDYLELYDG----PRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQ 1383
Query: 854 AS-HATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVE 912
CGG++ + +S F N YP +C W I + G ++L F+VE
Sbjct: 1384 MQWFVYGCGGELSGATGS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE 1439
Query: 913 EETDCGYDYMELFDGYDSTAPRLGRYCGSGPPE---EVYSAGDSVLVKFHSDDTITKKGF 969
+ C +D +E++ G D +PR+ + C PE +V S G+ + ++F +D +I +GF
Sbjct: 1440 YHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGF 1499
Query: 970 H 970
+
Sbjct: 1500 N 1500
Score = 289 bits (740), Expect = 8e-78
Identities = 192/673 (28%), Positives = 310/673 (46%), Gaps = 112/673 (16%)
Query: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
G +SP +P Y + + W ++V + +D+ + C+YD + + DG A
Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHA 1920
Query: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI--------------CG 436
L G +CG++ E ST + L F S S+ GKGF + A+ CG
Sbjct: 1921 RLIGAYCGTQT-ESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGACG 1979
Query: 437 GDVKKDYGHIQ--SPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
G ++ + SP +PD Y C W IQ + V L S +IE H +CAYD L
Sbjct: 1980 GFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDST-VELNILSLDIESHRTCAYDSLV 2038
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
+RDG + + + CG E P I+ST ++++F SD S+ +AGF +F K
Sbjct: 2039 IRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHK-------- 2090
Query: 555 NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPN 614
+CGG+L G ITSP +P+ YP N
Sbjct: 2091 -----------------------------------SCGGYLHADRGIITSPKYPETYPSN 2115
Query: 615 KNCIWQLVAPTQYRISLQFD--FFETEGNDVCKY-DFVEVRSGLTADSKL------HGKF 665
NC W ++ + I++ F+ F G+ C D++ +R+G S +G F
Sbjct: 2116 LNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHF 2175
Query: 666 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSY 725
CGS + + N M V+F SD++ +GFK + + C GG
Sbjct: 2176 CGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLAC----GG------------ 2219
Query: 726 ECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRV 785
+HD ++G +TSPN P YP +C W +++ P R+
Sbjct: 2220 ------NVYIHD--------------ADSAGYVTSPNHPHNYPPHADCIWILAAPPETRI 2259
Query: 786 KLTFME-MDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
+L F + DIE P C ++LE+ DG D+ AP+L +FCG+ P ++G M+LRF SD
Sbjct: 2260 QLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSD 2319
Query: 845 NSVQRKGFQASHA-TECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVE 903
NS GF+A ++ +CGG+V + H Y + CEW + G+ +
Sbjct: 2320 NSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPTL---PYRDNLFCEWHLQGLSGHYLT 2376
Query: 904 LVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDT 963
+ F+ F ++ + C D++E++D + S LGRYCG+ P+ + ++ ++ +V+F +D +
Sbjct: 2377 ISFEDFNLQNSSGCEKDFVEIWDNHTS-GNILGRYCGNTIPDSIDTSSNTAVVRFVTDGS 2435
Query: 964 ITKKGFHLRYTST 976
+T GF LR+ S+
Sbjct: 2436 VTASGFRLRFESS 2448
Score = 274 bits (701), Expect = 3e-73
Identities = 197/673 (29%), Positives = 298/673 (44%), Gaps = 110/673 (16%)
Query: 322 CGETLQDST-GNFSSPEYPN--GYSAHMHCVWRISVTPGE---KIILNFTSLDLYRSRLC 375
CG +L ++ GNF+SP Y YS +++C W +S P + I ++F L + C
Sbjct: 2570 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS-NPNQGNSSISIHFEDFYLESHQDC 2628
Query: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
+D +E R G PL R CG P P+V S++W+ F ++ GF A Y
Sbjct: 2629 QFDVLEFRVGD-ADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFT 2687
Query: 435 -CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 493
CGG D G I SPNYP+ Y C ++ +G + LTF F+IE H +CA+D +
Sbjct: 2688 DCGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSV 2747
Query: 494 EVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 553
VR+G S S +IG+YCG P I+S S++L + F SD S+ GF + +
Sbjct: 2748 TVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQ------ 2801
Query: 554 PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPP 613
TLG CGG NG+I SP WP+ +P
Sbjct: 2802 ------------TLG----------------------CGGIFHSDNGTIRSPHWPQNFPE 2827
Query: 614 NKNCIWQLVAPTQYRISLQFD--FFETEGNDVCKYDFVEVRSGLT-ADSKLHGKFCGSEK 670
N C W + + + FD F G+ C+ FV+V +G D L CG+
Sbjct: 2828 NSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVA 2887
Query: 671 PEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCR 730
P + + N F+S ++ GF A F S +C
Sbjct: 2888 PGPVITPSNTFTAVFQSQEAPAQ-GFSASFVS-------------------------RCG 2921
Query: 731 SGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFM 790
S F T SG I SPN+P +Y + CT+ I + P V LTF+
Sbjct: 2922 SNF------------------TGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFV 2963
Query: 791 EMDIESQP----ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNS 846
+E++ C D + + G + CG + P P+ G + L FYS+
Sbjct: 2964 SFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGP-VLLNFYSNEQ 3022
Query: 847 VQRKGFQASHAT-ECGG--QVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVE 903
+ GF+ S+ CGG + + T YS+A +YP + C + I + +E
Sbjct: 3023 ITDFGFKFSYRIISCGGVFNFSSGIITSPAYSYA-----DYPNDMHCLYTITVSDDKVIE 3077
Query: 904 LVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDT 963
L F F+V T C +DY+ ++DG +++ P LG++CGS P V S+ +S+L+ F +D
Sbjct: 3078 LKFSDFDVVPSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSF 3137
Query: 964 ITKKGFHLRYTST 976
T KG+ + + T
Sbjct: 3138 QTAKGWKMSFRQT 3150
Score = 271 bits (693), Expect = 2e-72
Identities = 193/682 (28%), Positives = 301/682 (44%), Gaps = 117/682 (17%)
Query: 321 ACGETLQ--DSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
ACG L+ D+ SP +P+ YS + C W I P + LN SLD+ R C YD
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYD 2035
Query: 379 YVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGD 438
+ +RDG A CG ++P PI ST +++ F S S+ GF A + CGG
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGY 2095
Query: 439 VKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAY--DYLEV 495
+ D G I SP YP+ Y + C W + V G + + F Q F+I DS DYL +
Sbjct: 2096 LHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVL 2155
Query: 496 RDGHSESSTLIG------RYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVD 549
R+G S +G +CG + ++ ++++++F+SD S GF + +
Sbjct: 2156 RNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY----- 2210
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFL----TKLNGSITSP 605
E + L ACGG + G +TSP
Sbjct: 2211 ----------EAKSL-------------------------ACGGNVYIHDADSAGYVTSP 2235
Query: 606 GWPKEYPPNKNCIWQLVAPTQYRISLQF-DFFETEGNDVCKYDFVEVRSGLTADSKLHGK 664
P YPP+ +CIW L AP + RI LQF D F+ E C +++E+R G+ +D+ + K
Sbjct: 2236 NHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSK 2295
Query: 665 FCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGS 724
FCG+ P S M + F+SDN+ + GFKA +
Sbjct: 2296 FCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY------------------------ 2331
Query: 725 YECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPD-KYPSKKECTWAISSTPGH 783
A C +V SG + S P Y C W + GH
Sbjct: 2332 ------------------SIAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGH 2373
Query: 784 RVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYS 843
+ ++F + ++++ C D +E++D + +LGR+CG+ P+ + + + +RF +
Sbjct: 2374 YLTISFEDFNLQNSSGCEKDFVEIWDNHTS-GNILGRYCGNTIPDSIDTSSNTAVVRFVT 2432
Query: 844 DNSVQRKGFQA---SHATECGGQVRADVKTKDLYSHAQFGDNNYPG----GVDCEWVIVA 896
D SV GF+ S ECGG ++ + T F NYP G CEW I A
Sbjct: 2433 DGSVTASGFRLRFESSMEECGGDLQGSIGT--------FTSPNYPNPNPHGRICEWRITA 2484
Query: 897 EEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS-GPPEEVYSAGDSVL 955
EG + L+F + C +++ +F+G S +P+L + C S E+ S+G+++
Sbjct: 2485 PEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMK 2544
Query: 956 VKFHSDDTITKKGFHLRYTSTK 977
V F +D + GF YTS++
Sbjct: 2545 VIFFTDGSRPYGGFTASYTSSE 2566
Score = 271 bits (693), Expect = 2e-72
Identities = 187/683 (27%), Positives = 307/683 (44%), Gaps = 120/683 (17%)
Query: 318 KCPACGETLQ----DSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRS 372
K ACG + DS G +SP +P+ Y H C+W ++ P +I L F D+ +
Sbjct: 2213 KSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVT 2272
Query: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
C +Y+E+RDG AP+ +FCG+ LP S+ +++ FRS ++ GF A Y
Sbjct: 2273 PNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYS 2332
Query: 433 -AICGGDVKKDYGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY 490
A CGG V G ++S +P YR + C W +Q G ++ ++F+ F ++ C
Sbjct: 2333 IAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEK 2392
Query: 491 DYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE 550
D++E+ D H+ S ++GRYCG PD I ++S+ ++FV+DGS+ +GF + F ++E
Sbjct: 2393 DFVEIWDNHT-SGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEE 2451
Query: 551 CSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKE 610
CGG L G+ TSP +P
Sbjct: 2452 ----------------------------------------CGGDLQGSIGTFTSPNYPNP 2471
Query: 611 YPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGS-E 669
P + C W++ AP RI+L F+ + C + V V +G+ ++S K C S
Sbjct: 2472 NPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVN 2531
Query: 670 KPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQC 729
I S N M+V F +D + GF A + S +D
Sbjct: 2532 VSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED------------------------ 2567
Query: 730 RSGFVLHDNKHDCKEAGCDHKVTST-SGTITSPNWPD--KYPSKKECTWAIS--STPGHR 784
A C + +T G TSP + Y C W +S +
Sbjct: 2568 ---------------AVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSS 2612
Query: 785 VKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPE-PVLATGSRMFLRFYS 843
+ + F + +ES +C +D LE F DA P++ R CG KP P++ S++++ F +
Sbjct: 2613 ISIHFEDFYLESHQDCQFDVLE-FRVGDADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVT 2671
Query: 844 DNSVQRKGFQASHA-TECGGQVRADVKTKDLYSHAQFGDN------NYPGGVD----CEW 892
+ V+ GF A ++ T+CGG Q GD+ NYP D C
Sbjct: 2672 NERVEHIGFHAKYSFTDCGG--------------IQIGDSGVITSPNYPNAYDSLTHCSS 2717
Query: 893 VIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGD 952
++ A +G+ + L F F++E T C +D + + +G +P +G+YCG+ P + S +
Sbjct: 2718 LLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSN 2777
Query: 953 SVLVKFHSDDTITKKGFHLRYTS 975
++V F+SD ++ GF+ + +
Sbjct: 2778 QLVVTFNSDHSLQGGGFYATWNT 2800
Score = 269 bits (687), Expect = 1e-71
Identities = 184/688 (26%), Positives = 295/688 (42%), Gaps = 102/688 (14%)
Query: 292 VNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWR 351
V+GV + TRL G + Q + CGE+L G+FS GY ++C W
Sbjct: 448 VDGVDSFSCECTRLWTGALCQVPQ----QVCGESLSGINGSFSYRSPDVGYVHDVNCFWV 503
Query: 352 ISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSR 411
I G+ + + FT L C +++++V DG A GRFCGS LP ++S+D+
Sbjct: 504 IKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNA 563
Query: 412 LWVEFRSSSNWVGKGFFAVYEAI---CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVS 468
L+ S G+GF +E CGG + YG I+SP YP +Y P + C+W + S
Sbjct: 564 LYFHLYSEHLRNGRGFTVRWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTS 623
Query: 469 EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLK 528
V TF + +E HD C DYLE+RDG L+G++C +++T +
Sbjct: 624 PDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIH 683
Query: 529 FVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCE 588
F SD I+ GF + Y +P R
Sbjct: 684 FHSDSQISDQGFHIT----------------------------------YLTSPSDLR-- 707
Query: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
CGG T G + P + + C++ + P +I + F E + ++
Sbjct: 708 --CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNY 765
Query: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
+EVR G T L GK CG+ I S N++ + FK D +V K F+A +
Sbjct: 766 IEVRDGET----LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY-------- 813
Query: 709 KDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYP 768
+ C ++T G I SP +P+ YP
Sbjct: 814 -----------------------------------QVACGDELTG-EGVIRSPFFPNVYP 837
Query: 769 SKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPE 828
++ C W I + L F +I S C D++E+ +P ++CG+ P
Sbjct: 838 GERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPS 897
Query: 829 PVLATGSRMFLRFYSDNSVQRKGFQASHATE---CGGQVRADVKTKDLYSHAQFGDNNYP 885
+ + + +++ F +S + GF A + E CG + T H N YP
Sbjct: 898 FITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGH----PNVYP 953
Query: 886 GGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPE 945
G++C W I+ + + + L+F+TF +E +C DY+E++D T+ LGRYCG P
Sbjct: 954 HGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS--LGRYCGKSIPP 1011
Query: 946 EVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+ S+G+S+++ F +D + +GF + Y
Sbjct: 1012 SLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 263 bits (673), Expect = 5e-70
Identities = 182/661 (27%), Positives = 278/661 (42%), Gaps = 105/661 (15%)
Query: 320 PACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDY 379
P CG L G+ SP YP Y CVW + +P + F +L L C DY
Sbjct: 588 PECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDY 647
Query: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY-----EAI 434
+E+RDG + PL G+FC + P+ +T + F S S +GF Y +
Sbjct: 648 LEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSDLR 707
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG+ G + P + ++ C++ ++ +G + + F E++ + +Y+E
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
VRDG TL+G+ CG IKS ++ +W++F D S+ KA F +
Sbjct: 768 VRDGE----TLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY---------- 813
Query: 555 NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPN 614
+ ACG LT G I SP +P YP
Sbjct: 814 ---------------------------------QVACGDELTG-EGVIRSPFFPNVYPGE 839
Query: 615 KNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVI 674
+ C W + P I L F FE + C+ D+VE+ S S + K+CG++ P I
Sbjct: 840 RTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFI 899
Query: 675 TSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFV 734
TS YN + V F ++ GF A F ++
Sbjct: 900 TSVYNFLYVTFVKSSSTENHGFMAKFSAE------------------------------- 928
Query: 735 LHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDI 794
+ C +T ++GTI SP P+ YP CTW I P H + L F +
Sbjct: 929 ---------DLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHL 979
Query: 795 ESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF-- 852
E C D+LEV+D + LGR+CG P + ++G+ + L F +D+ + +GF
Sbjct: 980 EFHYNCTNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLI 1037
Query: 853 ---QASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTF 909
S AT C D+ T ++ F NNYP +C + I G + + F F
Sbjct: 1038 NYEAISAATACLQDYTDDLGT---FTSPNF-PNNYPNNWECIYRITVRTGQLIAVHFTNF 1093
Query: 910 EVEEETDCGY-DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKG 968
+EE Y D++E+ DG +P LG + GS P + S + + +KF SD T+ G
Sbjct: 1094 SLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSG 1153
Query: 969 F 969
F
Sbjct: 1154 F 1154
Score = 247 bits (630), Expect = 4e-65
Identities = 179/682 (26%), Positives = 299/682 (43%), Gaps = 111/682 (16%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS---LDLYRSRLCWY 377
+CG L G +SP+YP Y ++++C W + V G I ++F + S
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150
Query: 378 DYVEVRDGFWRKAPL------RGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
DY+ +R+G +P G FCGS + ++D++++V+F S + G+GF Y
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Query: 432 EA---ICGGDV----KKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQS-FEIE 483
EA CGG+V G++ SPN+P +Y P CIW + + L F+ F+IE
Sbjct: 2211 EAKSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIE 2270
Query: 484 RHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVN 543
+C +YLE+RDG + ++ ++CG P S+ ++L+F SD S GF
Sbjct: 2271 VTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAK 2330
Query: 544 FFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSIT 603
+ A CGG + +G +
Sbjct: 2331 Y------------------------------------------SIAQCGGRVPGQSGVVE 2348
Query: 604 SPGWPK-EYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLH 662
S G P Y N C W L + + +++ F+ F + + C+ DFVE+ T+ + L
Sbjct: 2349 SIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGNIL- 2407
Query: 663 GKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTF 722
G++CG+ P+ I + N V F +D +V+ GF+ F S +EC D G
Sbjct: 2408 GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQG--------- 2458
Query: 723 GSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPG 782
+ GT TSPN+P+ P + C W I++ G
Sbjct: 2459 -------------------------------SIGTFTSPNYPNPNPHGRICEWRITAPEG 2487
Query: 783 HRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRF 841
R+ L F + + + P C +H+ VF+G + +P L + C S + ++G+ M + F
Sbjct: 2488 RRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIF 2547
Query: 842 YSDNSVQRKGFQASHATE----CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVI--V 895
++D S GF AS+ + CGG + + + S G NY ++CEW +
Sbjct: 2548 FTDGSRPYGGFTASYTSSEDAVCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 2606
Query: 896 AEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCG-SGPPEEVYSAGDSV 954
+ + + F+ F +E DC +D +E G D+ P + R CG S P + V
Sbjct: 2607 NQGNSSISIHFEDFYLESHQDCQFDVLEFRVG-DADGPLMWRLCGPSKPTLPLVIPYSQV 2665
Query: 955 LVKFHSDDTITKKGFHLRYTST 976
+ F +++ + GFH +Y+ T
Sbjct: 2666 WIHFVTNERVEHIGFHAKYSFT 2687
Score = 241 bits (616), Expect = 2e-63
Identities = 171/677 (25%), Positives = 294/677 (43%), Gaps = 103/677 (15%)
Query: 317 YKCPACGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLC 375
Y+ +CG S+G +SP Y Y MHC++ I+V+ + I L F+ D+ S C
Sbjct: 3032 YRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSC 3091
Query: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI- 434
+DY+ + DG PL G+FCGSK P + S+++ + + F++ S KG+ +
Sbjct: 3092 SHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTL 3151
Query: 435 -----CGGDVKKDYGHIQSPNYPDD--YRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDS 487
CGG + SP+ + Y + C+W I + LTF +F +E +
Sbjct: 3152 GPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST 3211
Query: 488 ---CAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
C YDY+++ DG SE++ L G +CG P S+ + L ++F+SD ++ + GF +
Sbjct: 3212 RQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 545 FKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITS 604
C G+Y + P +I+S
Sbjct: 3272 TIMDMPCG---------------GTYNATWTPQ-----------------------NISS 3293
Query: 605 PGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGK 664
P P C W + +P ++ + + D C ++++++ +
Sbjct: 3294 PNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTSQD-CTQNYLQLQDSPQGHGNSRFQ 3352
Query: 665 FCG--SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTF 722
FCG + V S + V FKS V + + F +C++D
Sbjct: 3353 FCGRNASAVPVFYSSMSTAMVIFKSG--VVNRNSRMSFTYQIADCNRDY----------- 3399
Query: 723 GSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPG 782
HK G + SP WPD Y + K+CT +++
Sbjct: 3400 --------------------------HKAF---GNLRSPGWPDNYDNDKDCTVTLTAPQN 3430
Query: 783 HRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFY 842
H + L F + IE+ EC D LEV +G ++ +P+LG++CG+ P PV + + ++LRF
Sbjct: 3431 HTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFK 3490
Query: 843 SDNSVQRKGFQ---ASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEG 899
SD+ +G++ S + CGG + D + ++ + YP CEWV+VA G
Sbjct: 3491 SDSVTSDRGYEIIWTSSPSGCGGTLYGD---RGSFTSPGY-PGTYPNNTYCEWVLVAPAG 3546
Query: 900 YGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVY-SAGDSVLVKF 958
V + F +++ DC +Y+ L+DG ++++P G YCG + ++ + V +KF
Sbjct: 3547 RLVTINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKF 3606
Query: 959 HSDDTITKKGFHLRYTS 975
H+D F L + S
Sbjct: 3607 HADYARRPSAFRLTWDS 3623
Score = 236 bits (603), Expect = 6e-62
Identities = 178/676 (26%), Positives = 285/676 (42%), Gaps = 109/676 (16%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLY-RSRL---CWY 377
CG +G SP YP Y +M+C + I P ++L F S L RS + C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
D V + G+ + CG ++P P+ L + F S+ GF Y I CG
Sbjct: 2980 DGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRIISCG 3038
Query: 437 GDVKKDYGHIQSPNYP-DDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEV 495
G G I SP Y DY C++ I VS+ + L F F++ SC++DYL +
Sbjct: 3039 GVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAI 3098
Query: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN 555
DG + S L+G++CG ++P ++KS+++ + L F +D G+ ++F +
Sbjct: 3099 YDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQ--------- 3149
Query: 556 RGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKE--YPP 613
TLG + CGG+LT N + SP Y
Sbjct: 3150 ----------TLGP------------------QQGCGGYLTGSNNTFASPDSDSNGMYDK 3181
Query: 614 NKNCIWQLVAPTQYRISLQFDFFETEGNDV---CKYDFVEVRSGLTADSKLHGKFCGSEK 670
N NC+W ++AP I L F+ F E C YD+V++ G + ++ L G FCGS
Sbjct: 3182 NLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTV 3241
Query: 671 PEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCR 730
P S N + V+F SD T+ ++GF A T+ + C
Sbjct: 3242 PAPFISSGNFLTVQFISDLTLEREGFNA----------------------TYTIMDMPC- 3278
Query: 731 SGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFM 790
G + T T I+SPN D CTW I S P +VK+T
Sbjct: 3279 ---------------GGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVW 3323
Query: 791 EMDIESQPECAYDHLEVFDGRDAKAPVLGRFCG-SKKPEPVLATGSRMFLRFYSDNSVQR 849
+ + SQ +C ++L++ D +FCG + PV + + + V R
Sbjct: 3324 ALQLTSQ-DCTQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNR 3382
Query: 850 KGFQAS--HATECGGQVRADVKTKDLYSHAQFGD-------NNYPGGVDCEWVIVAEEGY 900
+ +C H FG+ +NY DC + A + +
Sbjct: 3383 NSRMSFTYQIADCNRDY-----------HKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNH 3431
Query: 901 GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS 960
+ L F + +E +C D++E+ +G +S +P LG+YCG+ P V+S + + ++F S
Sbjct: 3432 TISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKS 3491
Query: 961 DDTITKKGFHLRYTST 976
D + +G+ + +TS+
Sbjct: 3492 DSVTSDRGYEIIWTSS 3507
Score = 228 bits (582), Expect = 2e-59
Identities = 171/676 (25%), Positives = 285/676 (42%), Gaps = 105/676 (15%)
Query: 317 YKCPACGETLQDSTGNFSSPEYPN-GYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLC 375
Y CG + +G S +P Y ++ C W + G + ++F +L S C
Sbjct: 2331 YSIAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGC 2390
Query: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI- 434
D+VE+ D + GR+CG+ +P+ I ++ + V F + + GF +E+
Sbjct: 2391 EKDFVEIWDNH-TSGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSM 2449
Query: 435 --CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
CGGD++ G SPNYP+ ++C WRI EG + L F + + H SC ++
Sbjct: 2450 EECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEH 2509
Query: 493 LEVRDGHSESSTLIGRYC-GYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
+ V +G +S + + C ++IKS+ + + + F +DGS GF ++ D
Sbjct: 2510 VIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED-- 2567
Query: 552 SRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKL-NGSITSPGWP-- 608
A CGG L G+ TSPG+
Sbjct: 2568 -------------------------------------AVCGGSLPNTPEGNFTSPGYDGV 2590
Query: 609 KEYPPNKNCIWQLVAPTQ--YRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFC 666
+ Y N NC W L P Q IS+ F+ F E + C++D +E R G AD L + C
Sbjct: 2591 RNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFRVG-DADGPLMWRLC 2649
Query: 667 GSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSY 725
G KP + + Y+ + + F ++ V GF A + D GG Q
Sbjct: 2650 GPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY------SFTDCGGIQ---------- 2693
Query: 726 ECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRV 785
SG ITSPN+P+ Y S C+ + + GH +
Sbjct: 2694 --------------------------IGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTI 2727
Query: 786 KLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDN 845
LTF + DIE CA+D + V +G ++P++G++CG+ P + + +++ + F SD+
Sbjct: 2728 TLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDH 2787
Query: 846 SVQRKGFQASHATE---CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGV 902
S+Q GF A+ T+ CGG +D T + N+P C W + + +
Sbjct: 2788 SLQGGGFYATWNTQTLGCGGIFHSDNGT----IRSPHWPQNFPENSRCSWTAITHKSKHL 2843
Query: 903 ELVFQTFEVEEETD--CGYDYMELFDGYDST-APRLGRYCGSGPPEEVYSAGDSVLVKFH 959
E+ F + D C +++++ G + L CG+ P V + ++ F
Sbjct: 2844 EISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQ 2903
Query: 960 SDDTITKKGFHLRYTS 975
S + +GF + S
Sbjct: 2904 SQEA-PAQGFSASFVS 2918
Score = 207 bits (528), Expect = 3e-53
Identities = 172/670 (25%), Positives = 270/670 (40%), Gaps = 107/670 (15%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG LQ S G F+SP YPN C WRI+ G +I L F +L L C ++V
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVI 2511
Query: 382 VRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY----EAICG 436
V +G +P + C S + I S+ + + V F + + GF A Y +A+CG
Sbjct: 2512 VFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG 2571
Query: 437 GDVKKD-YGHIQSPNYPD--DYRPSKVCIWRIQVSE--GFHVGLTFQSFEIERHDSCAYD 491
G + G+ SP Y +Y + C W + + + F+ F +E H C +D
Sbjct: 2572 GSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFD 2631
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE 550
LE R G ++ L+ R CG KP + S++W+ FV++ + GF +
Sbjct: 2632 VLEFRVGDADGP-LMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY------ 2684
Query: 551 CSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKE 610
CGG +G ITSP +P
Sbjct: 2685 ------------------------------------SFTDCGGIQIGDSGVITSPNYPNA 2708
Query: 611 YPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEK 670
Y +C L AP + I+L F F+ E + C +D V VR+G + +S + G++CG+
Sbjct: 2709 YDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSN 2768
Query: 671 PEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCR 730
P I S N + V F SD+++ GF A +
Sbjct: 2769 PRTIQSGSNQLVVTFNSDHSLQGGGFYATW------------------------------ 2798
Query: 731 SGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFM 790
+ + GC S +GTI SP+WP +P C+W + ++++F
Sbjct: 2799 ----------NTQTLGCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFD 2848
Query: 791 EMDI--ESQPECAYDHLEVFDG-RDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSV 847
+ +C ++V+ G + +L CG+ P PV+ T S F +
Sbjct: 2849 NNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVI-TPSNTFTAVFQSQEA 2907
Query: 848 QRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQ 907
+GF AS + CG ++ + DNN ++C +VI A V L F
Sbjct: 2908 PAQGFSASFVSRCGSNFTGPSGYIISPNYPKQYDNN----MNCTYVIEANPLSVVLLTFV 2963
Query: 908 TFEVEEET----DCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDT 963
+F +E + C D + + GY + CG P + AG VL+ F+S++
Sbjct: 2964 SFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAG-PVLLNFYSNEQ 3022
Query: 964 ITKKGFHLRY 973
IT GF Y
Sbjct: 3023 ITDFGFKFSY 3032
Score = 190 bits (482), Expect = 6e-48
Identities = 127/554 (22%), Positives = 224/554 (40%), Gaps = 88/554 (15%)
Query: 422 WVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFE 481
W G V + +CG + G + Y C W I+ G + +TF F
Sbjct: 462 WTG-ALCQVPQQVCGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFR 520
Query: 482 IERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFA 541
+E D+C +++L+V DG S S+ +GR+CG P ++ S+ + L+ S+ N GF
Sbjct: 521 LESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFT 580
Query: 542 VNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGS 601
V + E +P CGG LT GS
Sbjct: 581 VRW-----ETQQPE-----------------------------------CGGILTGPYGS 600
Query: 602 ITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKL 661
I SPG+P YPP ++C+W +V ++ F E +D C D++E+R G L
Sbjct: 601 IKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPL 660
Query: 662 HGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNT 721
GKFC + + + R+ F SD+ +S +GF + + +
Sbjct: 661 LGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSDLR------------- 707
Query: 722 FGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTP 781
C T G + P + ++C + +
Sbjct: 708 -------------------------CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQ 742
Query: 782 GHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRF 841
G ++++ F ++++ Q + + +++EV DG +LG+ CG+ + + + +++RF
Sbjct: 743 GEQIQINFTHVELQCQSDSSQNYIEVRDGET----LLGKVCGNGTISHIKSITNSVWIRF 798
Query: 842 YSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYG 901
D SV++ F+A + CG ++ T + + F N YPG C W I +
Sbjct: 799 KIDASVEKASFRAVYQVACGDEL-----TGEGVIRSPFFPNVYPGERTCRWTIHQPQSQV 853
Query: 902 VELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSD 961
+ L F FE+ C DY+E+ +P +YCG+ P + S + + V F
Sbjct: 854 ILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKS 913
Query: 962 DTITKKGFHLRYTS 975
+ GF ++++
Sbjct: 914 SSTENHGFMAKFSA 927
Score = 149 bits (377), Expect = 1e-35
Identities = 109/447 (24%), Positives = 195/447 (43%), Gaps = 75/447 (16%)
Query: 542 VNFFKEVDEC-SRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEA---ACGGFLTK 597
VN + ++EC S P G C++ + S+ C C + A C+ CG L+
Sbjct: 427 VNCTENINECLSNPCLNG--GTCVDGVDSFSCECTRLWTGA----LCQVPQQVCGESLSG 480
Query: 598 LNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTA 657
+NGS + Y + NC W + + + F FF E D C ++F++V G ++
Sbjct: 481 INGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSS 540
Query: 658 DSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQD 717
+ G+FCGS P + S N + S++ + +GF + + + EC GG
Sbjct: 541 SAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPEC----GGI--- 593
Query: 718 CVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAI 777
+T G+I SP +P YP ++C W +
Sbjct: 594 ---------------------------------LTGPYGSIKSPGYPGNYPPGRDCVWIV 620
Query: 778 SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRM 837
++P V TF + +E +C D+LE+ DG + P+LG+FC + P+ TG
Sbjct: 621 VTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFA 680
Query: 838 FLRFYSDNSVQRKGFQASHAT-----ECGGQV---RADVKTKDL---YSHAQFGDNNYPG 886
+ F+SD+ + +GF ++ T CGG ++ +L ++H +
Sbjct: 681 RIHFHSDSQISDQGFHITYLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTR-------- 732
Query: 887 GVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEE 946
C +++ +G +++ F E++ ++D +Y+E+ DG LG+ CG+G
Sbjct: 733 --QCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISH 786
Query: 947 VYSAGDSVLVKFHSDDTITKKGFHLRY 973
+ S +SV ++F D ++ K F Y
Sbjct: 787 IKSITNSVWIRFKIDASVEKASFRAVY 813
Score = 137 bits (344), Expect = 6e-32
Identities = 124/459 (27%), Positives = 188/459 (40%), Gaps = 88/459 (19%)
Query: 546 KEVDECSRPNRGGCEQ----RCLNTLGSYKC-SCDPGYELAPDKRRC------------- 587
++++EC N GGC C+NT GS C +C PGY+ D R C
Sbjct: 304 EDINECEI-NNGGCSVAPPVECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGC 360
Query: 588 --EAACGGFLTKLNGSITSPGWPKE-YPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVC 644
+A+C L L PG+ Y PN C+ QL L +T C
Sbjct: 361 HPDASCSSTLGSLPLCTCLPGYTGNGYGPN-GCV-QLSNICLSHPCLNGQCIDTVSGYFC 418
Query: 645 KYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDK 704
K D SG T G C E +++
Sbjct: 419 KCD-----SGWT------GVNCTENINECLSNP--------------------------- 440
Query: 705 DECSKDNGGCQQDCVNTFGSYECQCR---SGFVLHDNKHDCKEAGCDHKVTSTSGTITSP 761
C NGG CV+ S+ C+C +G + + C E+ ++ +G+ +
Sbjct: 441 --CL--NGGT---CVDGVDSFSCECTRLWTGALCQVPQQVCGES-----LSGINGSFSYR 488
Query: 762 NWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRF 821
+ Y C W I + G +++TF +ES C ++ L+V+DG + A LGRF
Sbjct: 489 SPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRF 548
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT---ECGGQVRADVKTKDLYSHAQ 878
CGS P +L++ + ++ YS++ +GF T ECGG + T S
Sbjct: 549 CGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGG-----ILTGPYGSIKS 603
Query: 879 FG-DNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGR 937
G NYP G DC W++V V F T +E DC DY+E+ DG P LG+
Sbjct: 604 PGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGK 663
Query: 938 YCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTST 976
+C + + + G + FHSD I+ +GFH+ Y ++
Sbjct: 664 FCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTS 702
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 228 bits (581), Expect = 2e-59
Identities = 183/647 (28%), Positives = 291/647 (44%), Gaps = 125/647 (19%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
C G+ + G I SP YP+ Y + CIW+I V+EG + + SF E++ +D LE
Sbjct: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVD--ECS 552
+ DG ++ +G + G P + STS++L+L F SD S+ AGF + + K V C
Sbjct: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY-KTVGLAACQ 1917
Query: 553 RPNRGGC-----EQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAAC 591
P ++ +N + S++C +PGY L P R C A C
Sbjct: 1918 EPALPSNSIKIGDRYMVNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC 1975
Query: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
GG L+ L G I SPG+P YP N +C W++ P Y +QF F TE N +DF+E+
Sbjct: 1976 GGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEI 2031
Query: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK-AHFFSDKDECSK- 709
++G S + G+F G++ P + S + + F SD++ +++GFK A+ + C
Sbjct: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
Query: 710 ---DNGGCQQDCVNTFGSYECQCRSGFVLHDN-----KHDCK----------EAGCDHKV 751
NG + S +C G++L + +H +A C + V
Sbjct: 2092 PPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNV 2151
Query: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
TS +GTI SP +PD+YP K+C W I+ PGH V + F + Q E D++ V+DG
Sbjct: 2152 TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLL----QTEAVNDYIAVWDGP 2207
Query: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD-----------NSVQRKGFQASHAT-- 858
D +P LG F G+ E ++ +++ L+F+SD ++ Q K Q A
Sbjct: 2208 DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQ 2267
Query: 859 ----------ECGGQVR-----------ADVKTKDLYSHAQFGDN--------------- 882
E G V+ D+ T L S QF +
Sbjct: 2268 AEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRT 2327
Query: 883 ---------NYPGGV----DCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYD 929
YPG C W I E Y + + TF+ E++ +D +E+FDG
Sbjct: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFDGSS 2383
Query: 930 STAPRLGRYCGSGPPEEVY-SAGDSVLVKFHSDDTITKKGFHLRYTS 975
+P L G+ + + S + + +++ +D +KKGF +RY +
Sbjct: 2384 GQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
Score = 199 bits (506), Expect = 1e-50
Identities = 184/672 (27%), Positives = 271/672 (40%), Gaps = 126/672 (18%)
Query: 290 YEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCV 349
Y + G K QR + + R + + CG L+ +G +SP YP Y + HCV
Sbjct: 380 YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
Query: 350 WRISVTPGEKII-LNFTSLDLYRSRLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIV 406
W I+ T +K+I L F +L R YD + V D + GS +P+ IV
Sbjct: 440 WVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
Query: 407 STDSRLWVEFRSSSNWVGKGFFAVYEAI----CGGDVKKDYGH----------------- 445
S +++W+ +S + GF AVY+ I CG YG
Sbjct: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECP 555
Query: 446 ------------IQSPNYPDDYRPSKV--CIWRIQVSEGF-------------------- 471
Q N +PS V C + S G
Sbjct: 556 AAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLI 615
Query: 472 ------HVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRL 525
+ L F F++E +D+L V+D T++G + G E P + S+ +
Sbjct: 616 ISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIV 671
Query: 526 WLKFVSDGSINKAGFAVNFFK-EVDECSRP------NRGG------------CEQRCLNT 566
L+F SD S GF + + +EC P R G C+ + T
Sbjct: 672 RLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKT 731
Query: 567 LGSYKCSC---DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA 623
GS +C D + RCEA CGG LT +G I PGWP Y + +C W + A
Sbjct: 732 QGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEA 791
Query: 624 PTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRV 683
+ I + FD F+TE N YD +EVR G + S L G++ G++ P+ + S N M +
Sbjct: 792 KPGHSIKITFDRFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYL 847
Query: 684 EFKSDNTVSKKGFKAHFFS---DKDECSKD----NGGCQQDCVNTFGSYECQCRSGFVLH 736
F +DN+ S GF H+ S + D C NG + C G+ L
Sbjct: 848 LFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLS 907
Query: 737 DNK-------HDCK------EAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGH 783
D++ H +A C + SGT+ SP +PD YP+ CTW I + G
Sbjct: 908 DDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGK 967
Query: 784 RVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMF---LR 840
V++ F +ES ++D+L + + PV R GS P + A F LR
Sbjct: 968 GVQMIFHTFHLES----SHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLR 1022
Query: 841 FYSDNSVQRKGF 852
F SD S+ +GF
Sbjct: 1023 FISDFSISYEGF 1034
Score = 196 bits (497), Expect = 1e-49
Identities = 145/466 (31%), Positives = 218/466 (46%), Gaps = 61/466 (13%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG VK + G + SPN+P +Y + CI++I+ G + L +SF++ D+
Sbjct: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT----- 1157
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDI-KSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
L+V DG SS +G + E I STS+ LWL+F ++GS GF + + ++ +
Sbjct: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
Query: 551 CSRPN------RGGCEQRCLNTLGSYKCSCDPGYE---------LAPDKR-------RCE 588
C P R E +T+ Y SC+PGY L+ D+R C
Sbjct: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLY--SCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
Query: 589 AACGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
A CGG + +G I SPG+P Y N +C W + A ISL F F+TE +D
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 1331
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSD---- 703
++V G L ++ GS PE I S +N++ ++F SD +SK GF F +
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 704 -KDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDN-KHDCKE---------------AG 746
D NG D + QC G+ L K C + A
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
C +T +G I SPN+P YP KEC W + P + L F ++E +YD L
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDFLH 1507
Query: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
+++G D+ +P++G + GS+ PE + ++G+ +FL F SD SV GF
Sbjct: 1508 IYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
Score = 190 bits (483), Expect = 5e-48
Identities = 139/480 (28%), Positives = 219/480 (45%), Gaps = 73/480 (15%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG++ G I SPNYP Y P K C WR++V+ F + L F+SF +E +YD+
Sbjct: 1450 AACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDF 1505
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
L + +G +S LIG Y G + P+ I+S+ + L+L F SD S+ +GFA+ F ++ E C
Sbjct: 1506 LHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREAC 1565
Query: 552 SRP------NRGGCEQRCLNTLGSYKCSCDPGYELAPDKR------------------RC 587
P R G + + +T+ +Y+ CD GY++ C
Sbjct: 1566 FDPGNIMNGTRVGTDFKLGSTI-TYQ--CDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Query: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
A CGG T G + SP +P Y + C++ + P ++ + QF +F+T ND+
Sbjct: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDL---- 1678
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
E+ G A ++L GS E + + N + + F + + S +GF HF
Sbjct: 1679 -AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF--HFVYQAVP 1735
Query: 702 -SDKDECS---KDNGGCQQDCVNTFGS-YECQCRSGFVL------------------HDN 738
+ +CS + G + + GS +C G++L +D
Sbjct: 1736 RTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDT 1795
Query: 739 KHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP 798
C C T GTI SP +P+ Y + C W I T G +++ + E
Sbjct: 1796 IPSC-VVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN- 1853
Query: 799 ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
+D LE+ DG D AP LG F G+ P + +T ++++L F SD SV GF + T
Sbjct: 1854 ---WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 1910
Score = 187 bits (474), Expect = 5e-47
Identities = 163/635 (25%), Positives = 255/635 (40%), Gaps = 124/635 (19%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG G + SPNYP +Y ++C++ I V + F V F F+ + D
Sbjct: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ-----TALNDL 1678
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
E+ DG + L+ G + + +TS+++ L+F + + GF ++ V
Sbjct: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHF-VYQAVPRT 1737
Query: 552 SRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR------------------ 585
S E R +GS + C+PGY L
Sbjct: 1738 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
Query: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
C C G T+ G+I SPG+P+ Y N NCIW+++ I +Q F TE N
Sbjct: 1798 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 1853
Query: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF----- 700
+D +E+ G + G F G+ P ++ S N + + F+SD +V+ GF +
Sbjct: 1854 WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGL 1913
Query: 701 FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE--------------A 745
+ ++ N D QC G+ L H C A
Sbjct: 1914 AACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIA 1973
Query: 746 GCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
C +++ G I SP +P YP+ +CTW IS G+ + F+ E+ +D L
Sbjct: 1974 TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFL 2029
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF----QASHATEC- 860
E+ +G +P++G+F G+ P +L+T + FYSD+S R+GF QA C
Sbjct: 2030 EIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCP 2089
Query: 861 -------GGQVRADVKTKDLYSH---------------AQFGDN---NYP---------- 885
G + +D S Q G N NYP
Sbjct: 2090 DPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGY 2149
Query: 886 ------GGV-------------DCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD 926
G + DC W+I G+GV + F +T+ DY+ ++D
Sbjct: 2150 NVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLL----QTEAVNDYIAVWD 2205
Query: 927 GYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSD 961
G D +P+LG + G+ E YS+ + VL+KFHSD
Sbjct: 2206 GPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
Score = 186 bits (472), Expect = 9e-47
Identities = 179/681 (26%), Positives = 267/681 (39%), Gaps = 160/681 (23%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG V+ G I+SP +P Y C W I E + L+F +F +E +D L
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-AVNFFKEVDECSR 553
V DG + L R G++ P I ST S L L F +D +++ GF A+ C
Sbjct: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
Query: 554 PN---RGGCEQRCLNTLGSYKCSCDPGYEL----------APDKR----------RCEAA 590
P +G N + SC PGY L +P R E A
Sbjct: 148 PGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGA 207
Query: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
CGG L + SI+SP +P EY N +C W ++A I+L F F+ E YDF+E
Sbjct: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFLE 263
Query: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF---------- 700
+ SG A S G P + S N +R+ F SD+ +KGF A F
Sbjct: 264 I-SGTEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKS 319
Query: 701 -----FSDKDECSKDN----GGCQ-------------------QDCVNTFGSYECQCRSG 732
KD K++ GG D + + C
Sbjct: 320 RGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDN 379
Query: 733 FVLH------------------DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECT 774
+VL D++ C+ C + SG ITSPN+P +Y C
Sbjct: 380 YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
Query: 775 WAISST-PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA--KAPVLGRFCGSKKPEPVL 831
W I++T P +KL F E ++E YD L V D VL GS P+ ++
Sbjct: 440 WVITTTDPDKVIKLAFEEFELER----GYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
Query: 832 ATGSRMFLRFYSDNSVQRKG----FQASHATECG--GQVRADVKTKDLYSHA-------- 877
+ ++M+L SD+S+ G +Q CG G +T + H
Sbjct: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECP 555
Query: 878 -----------------QFGDN----------------------NYP----GGVDCEWVI 894
Q+ N NYP ++C W+I
Sbjct: 556 AAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLI 615
Query: 895 VAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSV 954
++E G + L+F F+VE + +D++ + D S LG + G+ P ++ S+G V
Sbjct: 616 ISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIV 671
Query: 955 LVKFHSDDTITKKGFHLRYTS 975
++F SD + T +GF++ YT+
Sbjct: 672 RLEFQSDHSTTGRGFNITYTT 692
Score = 182 bits (462), Expect = 1e-45
Identities = 165/648 (25%), Positives = 273/648 (42%), Gaps = 124/648 (19%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
+A+CGG ++ G + SP +PD Y S C W I+VS G V + F +F +E ++D
Sbjct: 928 DALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES----SHD 983
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKST---SSRLWLKFVSDGSINKAGFAVNFFK-E 547
YL + + S S + R G P IK+ + L+F+SD SI+ GF + F + +
Sbjct: 984 YLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYD 1042
Query: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
++ C P +R G S SC GY L + RC
Sbjct: 1043 LEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
Query: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
A CG + G++ SP +P Y N CI+++ I L+ F+ D K
Sbjct: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK--- 1159
Query: 649 VEVRSGLTADSKLHGKFCGSE-KPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDE 706
V G + S+ G F +E ++ S N++ +EF ++ + + +GF+ + S D +
Sbjct: 1160 --VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
Query: 707 CSKDNGGCQQDCVNTFGSYE-----CQCRSGFVLH-DNKHDCKE--------------AG 746
C + G + C G+ +H N C A
Sbjct: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAE 1277
Query: 747 CDHKV-TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
C ++ +TSG I SP +P Y + CTW I + PG + L F+ D E A+D L
Sbjct: 1278 CGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFD----TEMAHDIL 1333
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT------- 858
+V+DG +L + GS PE + +T + + L+F SD + + GF +T
Sbjct: 1334 KVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCN 1393
Query: 859 -----------------------EC--GGQVRADVKTKDLYSHAQF-------------G 880
+C G Q++ K + + +F G
Sbjct: 1394 DPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACG 1453
Query: 881 DN-----------NYP----GGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELF 925
N NYP G +C+W + + + L+F++F +E YD++ ++
Sbjct: 1454 GNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDFLHIY 1509
Query: 926 DGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+G DS +P +G Y GS PE + S+G+S+ + F SD ++ GF + +
Sbjct: 1510 EGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF 1557
Score = 180 bits (457), Expect = 5e-45
Identities = 146/469 (31%), Positives = 214/469 (45%), Gaps = 66/469 (14%)
Query: 433 AICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
A CGG + G I SP YP Y + C W I+ G + L F F+ E A+D
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHD 1331
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE- 550
L+V DG +S L+ + G P+DI ST + L L+F SD I+K+GF++ F +
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 551 CSRPN------RGGCEQRCLNTLGSYKCSCDPGYELA-----------------PDKRRC 587
C+ P R G + +T+ CDPGY+L PD C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTV---TFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Query: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
AACGG LT G I SP +P+ YPP K C W++ + I+L F F E + YD
Sbjct: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YD 1504
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
F+ + G ++S L G + GS+ PE I S N++ + F+SD +V GF F E
Sbjct: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREA 1564
Query: 708 SKDNG----GCQQDCVNTFGS-YECQCRSGF-VLHDNKHDCK----------------EA 745
D G G + GS QC SG+ +L + C A
Sbjct: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA 1624
Query: 746 GCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
C + T + G + SPN+P Y + + C ++I+ V F+ + + A + L
Sbjct: 1625 PCGGQYTGSEGVVLSPNYPHNYTAGQICLYSIT------VPKEFVVFGQFAYFQTALNDL 1678
Query: 806 -EVFDGRDAKAPVLGRFCGSKKPEPV-LATGSRMFLRFYSDNSVQRKGF 852
E+FDG A+A +L GS E + LAT +++ LRF + + +GF
Sbjct: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 1727
Score = 167 bits (424), Expect = 3e-41
Identities = 133/472 (28%), Positives = 209/472 (44%), Gaps = 62/472 (13%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG + G I SP +P Y + C WRI + G+ + F +F E + +D+
Sbjct: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDF 2028
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
LE+++G +S +IG++ G + P + ST+ + F SD S N+ GF + + E+ C
Sbjct: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
Query: 552 SRP---NRGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEAACG 592
P G + S C PGY L RC+A CG
Sbjct: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCG 2148
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
+T NG+I SPG+P EYP K+CIW + P + + + F +TE + D++ V
Sbjct: 2149 YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVW 2204
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF---KAHFFSDKDECSK 709
G +S G F G+ E S N + ++F SD S GF H F K +C
Sbjct: 2205 DGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD--FSNGGFFVLNFHAFQLK-KCQP 2261
Query: 710 DNGGCQQDCVNTFGSYEC------QCRSGFVLHDNKH-DCK--------------EAGC- 747
Q + + +E QC G+ L CK EA C
Sbjct: 2262 PPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCP 2321
Query: 748 -DHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
+ T +SG I SP +P Y + + C+W+I P + + + E Q +D LE
Sbjct: 2322 ANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALE 2377
Query: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGS-RMFLRFYSDNSVQRKGFQASHA 857
VFDG ++P+L G+ + + S +++LR+ +D++ +KGF+ +A
Sbjct: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA 2429
Score = 160 bits (405), Expect = 5e-39
Identities = 139/525 (26%), Positives = 217/525 (41%), Gaps = 107/525 (20%)
Query: 418 SSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF 477
+ ++W F E CGG ++ I SP++P +Y + C W I G + L F
Sbjct: 191 NGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVF 250
Query: 478 QSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINK 537
F++E YD+LE+ + S L G P + S+ + L L F SD + +
Sbjct: 251 TDFQLEE----GYDFLEISGTEAPSIWLTGM----NLPSPVISSKNWLRLHFTSDSNHRR 302
Query: 538 AGFAVNFF--KEVDECSR-----PNRGGCEQRCLNTLG---------------------- 568
GF F K ++ SR P++ G + + + G
Sbjct: 303 KGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAG 362
Query: 569 --------SYKCSCDPGYELAPDKRR------------------CEA-ACGGFLTKLNGS 601
+ + SC+ Y L K C A CG L +G
Sbjct: 363 SDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGV 422
Query: 602 ITSPGWPKEYPPNKNCIWQLVAPTQYR-ISLQFDFFETEGNDVCKYDFVEVR-SGLTADS 659
ITSP +P +Y N +C+W + + I L F+ FE E YD + V +G D+
Sbjct: 423 ITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDT 478
Query: 660 K-LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDC 718
+ + GS P++I S N M + +SD+++ GFKA + E K GGC
Sbjct: 479 RSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVY----QEIEK--GGCGDPG 532
Query: 719 VNTFG-------------SYECQ------------CRSGFVLHDNKHDCKEAGCDHKVTS 753
+ +G ++EC C+ NK C + C T+
Sbjct: 533 IPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFS-CFFNFTA 591
Query: 754 TSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
+SG I SPN+P++Y + C W I S PG R+ L F + D+E Q +D L V D +
Sbjct: 592 SSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGIS 647
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
VLG F G++ P + ++G + L F SD+S +GF ++ T
Sbjct: 648 DITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
Score = 124 bits (312), Expect = 3e-28
Identities = 130/512 (25%), Positives = 200/512 (39%), Gaps = 110/512 (21%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG TL G SP +P Y ++ C WRIS+ G + F + + +D++E
Sbjct: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLE 2030
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----C-- 435
+++G + +P+ G+F G+ LP ++ST + F S + +GF Y+A C
Sbjct: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPD 2090
Query: 436 ------GGDVKKDYGHIQSP--------------------------NYP----------- 452
G + DY QS NYP
Sbjct: 2091 PPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYN 2150
Query: 453 --------------DDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG 498
D+Y K CIW I V G V + F + E DY+ V DG
Sbjct: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVNDYIAVWDG 2206
Query: 499 HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSRPNRG 557
++S +G + G + S+++++ LKF SD S N F +NF ++ +C P
Sbjct: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLKKCQPPPAV 2265
Query: 558 GCEQRCLN----TLGSY-KCSCDPGYELA----------------PDKRRCEAAC--GGF 594
+ +G + K C PGY L CEA C
Sbjct: 2266 PQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEV 2325
Query: 595 LTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG 654
T +G I SPG+P Y ++ C W + Y I++ D F++E ++D +EV G
Sbjct: 2326 RTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK----QFDALEVFDG 2381
Query: 655 LTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS----K 709
+ S L G+ + TS+ N + + + +D+ SKKGFK + + CS
Sbjct: 2382 SSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA--PYCSLTHPL 2439
Query: 710 DNGGCQQDCVNTFGS---YECQCRSGFVLHDN 738
NGG GS Y C+ V H N
Sbjct: 2440 KNGGILNRTAGAVGSKVHYFCKPGYRMVGHSN 2471
Score = 68.2 bits (165), Expect = 4e-11
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 4/112 (3%)
Query: 743 KEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAY 802
K C V +GTI SP +P YP+ CTW I + +R++L+F +E +
Sbjct: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----F 83
Query: 803 DHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA 854
D L V+DG+ + + R G + P +++TGS + L F +D +V +GF+A
Sbjct: 84 DILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKA 135
Score = 66.6 bits (161), Expect = 1e-10
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACG L G SP YP Y C WR+ V P I L F S ++ S YD++
Sbjct: 1451 ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFL 1506
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
+ +G +PL G + GS+ PE I S+ + L++ FRS ++ VG FA+
Sbjct: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDAS-VGLSGFAI 1555
Score = 65.9 bits (159), Expect = 2e-10
Identities = 39/112 (34%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACG TL+ ++ + SSP +P+ Y + C W I PG+ I L FT L YD++
Sbjct: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFL 262
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
E+ +AP G LP P++S+ + L + F S SN KGF A ++
Sbjct: 263 EISG---TEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
Score = 64.3 bits (155), Expect = 5e-10
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 4/98 (4%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
+YP +DC W I GYG + F F T+ +D++E+ +G T+P +G++ G+
Sbjct: 1994 SYPNNLDCTWRISLPIGYGAHIQFLNFS----TEANHDFLEIQNGPYHTSPMIGQFSGTD 2049
Query: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD 980
P + S L+ F+SD + ++GF L Y + + Q+
Sbjct: 2050 LPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQN 2087
Score = 63.5 bits (153), Expect = 9e-10
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG +Q G SP +P+GY + +C W I +I L+F + L +D +
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----CG- 436
V DG ++ L+ R G +LP IVST S L + F + +GF A+YE + CG
Sbjct: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
Query: 437 -GDVKKDYGHIQSPNYPDDYRPS 458
G++ K H N D R S
Sbjct: 148 PGEILKGVLHGTRFNIGDKIRYS 170
Score = 62.8 bits (151), Expect = 2e-09
Identities = 29/96 (30%), Positives = 55/96 (57%), Gaps = 4/96 (4%)
Query: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Y + CEW+I A+ G+ +++ F F+ T+ YD +E+ DG S++P +G Y G+
Sbjct: 779 YKDSLHCEWIIEAKPGHSIKITFDRFQ----TEVNYDTLEVRDGPASSSPLIGEYHGTQA 834
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
P+ + S G+ + + F +D++ + GF + Y S +
Sbjct: 835 PQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLE 870
Score = 62.0 bits (149), Expect = 3e-09
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
C G SP YP Y +++C+W+I VT G I + S ++ +D +E
Sbjct: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
+ DG AP G F G+ +P + ST ++L++ F+S + GF Y+ +
Sbjct: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
Score = 60.5 bits (145), Expect = 8e-09
Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 9/119 (7%)
Query: 859 ECGGQVRADVKTKDLY-SHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 917
ECGGQ+ A + L + DNN + C W+I A+ G + L F F+ T+
Sbjct: 1277 ECGGQIHAATSGRILSPGYPAPYDNN----LHCTWIIEADPGKTISLHFIVFD----TEM 1328
Query: 918 GYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTST 976
+D ++++DG + L + GS PE+++S +S+ ++F SD I+K GF ++++++
Sbjct: 1329 AHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTS 1387
Score = 59.3 bits (142), Expect = 2e-08
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 16/169 (9%)
Query: 269 IMHYARNTFSRGIFLDTIV-----PKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPA-C 322
I +Y G F DT+V P Y ++G T LS + L C A C
Sbjct: 1223 IPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNT----LTCLSGDRRVWDKPLPSCIAEC 1278
Query: 323 GETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
G + +T G SP YP Y ++HC W I PG+ I L+F D + +D ++
Sbjct: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA----HDILK 1334
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
V DG L + GS LPE I ST + L ++F S ++ K F++
Sbjct: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQF-DSDFFISKSGFSI 1382
Score = 57.4 bits (137), Expect = 7e-08
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 318 KCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCW 376
+C A CG + G SP +P+ Y C+W I+V PG + +NFT L
Sbjct: 2142 RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN--- 2198
Query: 377 YDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
DY+ V DG + +P G F G+ E S+ +++ ++F S++ GFF +
Sbjct: 2199 -DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFH--SDFSNGGFFVL 2249
Score = 53.9 bits (128), Expect = 7e-07
Identities = 38/118 (32%), Positives = 57/118 (48%), Gaps = 12/118 (10%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG +R T S F + Y DC W I+AE G + LVF F++EE GY
Sbjct: 208 CGGTLRG---TSSSISSPHF-PSEYENNADCTWTILAEPGDTIALVFTDFQLEE----GY 259
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTK 977
D++E+ + AP + G P V S+ + + + F SD +KGF+ ++ K
Sbjct: 260 DFLEI---SGTEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
Score = 53.1 bits (126), Expect = 1e-06
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Query: 303 TRLSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII 361
T L G + L +C A CG +++ + G SP +P+ Y + C+++I G+ I
Sbjct: 1085 TCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIH 1144
Query: 362 LNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIV-STDSRLWVEFRSSS 420
L S L+ D ++V DG + G F ++L I+ ST + LW+EF ++
Sbjct: 1145 LRTRSFQLFEG-----DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNG 1199
Query: 421 NWVGKGFFAVY 431
+ +GF Y
Sbjct: 1200 SDTDQGFQLTY 1210
Score = 51.2 bits (121), Expect = 5e-06
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Query: 854 ASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE 913
A+ CGG V+ T + + YP +C W+I+ E ++L F TF +EE
Sbjct: 26 AAKGQNCGGLVQGPNGTIESPGFP----HGYPNYANCTWIIITGERNRIQLSFHTFALEE 81
Query: 914 ETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+ +D + ++DG R G P + S G + + F +D ++ +GF Y
Sbjct: 82 D----FDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALY 137
Score = 47.0 bits (110), Expect = 9e-05
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG S G SP YP+ Y+A C++ I+V P E ++ F +++ L D E
Sbjct: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITV-PKEFVV--FGQFAYFQTAL--NDLAE 1680
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
+ DG +A L GS E + ++T +++ + F + S +GF VY+A+
Sbjct: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 12/118 (10%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG ++ T F YP ++C W I G GV+++F TF +E +
Sbjct: 931 CGGYIQGKSGTVLSPGFPDF----YPNSLNCTWTIEVSHGKGVQMIFHTFHLES----SH 982
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYS---AGDSVLVKFHSDDTITKKGFHLRYT 974
DY+ + + + P + R GS P + + + ++F SD +I+ +GF++ ++
Sbjct: 983 DYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 859 ECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCG 918
ECG V+ + T + DNN+ +C + I E G G+ L ++F++ E
Sbjct: 1104 ECGASVKGNEGTLLSPNFPSNYDNNH----ECIYKIETEAGKGIHLRTRSFQLFEG---- 1155
Query: 919 YDYMELFDGYDSTAPRLGRYCGSGPPEEVY-SAGDSVLVKFHSDDTITKKGFHLRYTS 975
D ++++DG DS++ LG + + + S + + ++F+++ + T +GF L YTS
Sbjct: 1156 -DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS 1212
Score = 41.2 bits (95), Expect = 0.005
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 318 KCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY 377
+CPA E S+G SP YP Y C W I V P I + +D ++S +
Sbjct: 2319 QCPA-NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITI---FVDTFQSEK-QF 2373
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEP-IVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
D +EV DG ++PL G+ + S ++L++ + + KGF Y A
Sbjct: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 217 bits (553), Expect = 4e-56
Identities = 184/688 (26%), Positives = 294/688 (42%), Gaps = 165/688 (23%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG++ + G I SP +P+ Y S C+W+I V EG + + SF E++ +D LE
Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF----FKEVDE 550
V DG + T++G + G P + STS++L+L F SD S++ AGF + + E
Sbjct: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911
Query: 551 CSRPNRG--GCEQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAACG 592
+ P+ G E+ +N + S++C +PGY L P R C A CG
Sbjct: 1912 PAVPSNGVKTGERYLVNDVVSFQC--EPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCG 1969
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
G + ++ G I SPG+P YP N +C W++ P + +QF F TE N +D++E+R
Sbjct: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIR 2025
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS---------- 702
+G S++ G+F GSE P + S + V F SD++ ++ GFK +
Sbjct: 2026 NGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSF 2085
Query: 703 ----DKDECSKDNG--------------GCQ----QDC---------------VNTFGSY 725
D E + N GC+ Q+C N S
Sbjct: 2086 LRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSV 2145
Query: 726 ECQCRSGFVLHDN-----KHDCK----------EAGCDHKVTSTSGTITSPNWPDKYPSK 770
+C G+ L + +H E C +TS++GT+ SP +P Y S
Sbjct: 2146 TFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSS 2205
Query: 771 KECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPV 830
++C W I+ GH V+L + Q E + D + ++DG AP LG F S + V
Sbjct: 2206 QDCVWLITVPIGHGVRLNLSLL----QTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTV 2261
Query: 831 LATGSRMFLRFYSD---NSVQRKGFQASHATEC--------------------GGQVR-- 865
++ +++ L+F+ D + F A T+C G VR
Sbjct: 2262 QSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYR 2321
Query: 866 ---------ADVKTKDLYSHAQFG------------------------DNNYPGGV---- 888
++ T L ++ QF +YPG
Sbjct: 2322 CLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQ 2381
Query: 889 DCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS-GPPEEV 947
C W++ E Y + L + F E++ YD E+FDG +P L G+ P V
Sbjct: 2382 TCSWLVRVEPDYNISLTVEYFLSEKQ----YDEFEIFDGPSGQSPLLKALSGNYSAPLIV 2437
Query: 948 YSAGDSVLVKFHSDDTITKKGFHLRYTS 975
S+ +SV +++ SD +KGF +RY++
Sbjct: 2438 TSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Score = 199 bits (506), Expect = 1e-50
Identities = 138/468 (29%), Positives = 223/468 (47%), Gaps = 55/468 (11%)
Query: 434 ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDY 492
+C ++ G I SPN+P Y + C+W I ++ + L F+ F++ER YD
Sbjct: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDT 459
Query: 493 LEVRDG--HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVD 549
L V DG + T++ G PD I ST+ ++WL F +DGS + GF ++ + E
Sbjct: 460 LTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQG 519
Query: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
C P G E + + K C P +EL K C +C
Sbjct: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCF 579
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
T +G + SP +P++Y + +C+W ++A + RI L F+ + E ++DF+ ++
Sbjct: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIK 635
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG 712
G TA++ + G F G++ P ITS + R+EF++D++ K+GF F + + D G
Sbjct: 636 DGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPG 695
Query: 713 G--------------------CQQDCVNTFGSYECQC--RSGFVLHDNKHDCKEAGCDHK 750
C + + T GS C + G V+ ++ EA C
Sbjct: 696 VPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGH 755
Query: 751 VTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDG 810
+TS SGTI SP WP Y C W I + PG+ +K+TF + E YD LEV DG
Sbjct: 756 LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRF----KTEVNYDTLEVRDG 811
Query: 811 RDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
R AP++G + G++ P+ +++T + ++L F +D S GFQ + T
Sbjct: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET 859
Score = 197 bits (502), Expect = 3e-50
Identities = 140/464 (30%), Positives = 211/464 (45%), Gaps = 57/464 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG V G + SPN+P +Y + CI+ IQ G + L ++FE+ D
Sbjct: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGD-----V 1150
Query: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
L+V DG++ S+ L+G + E + STSS LWL F++D GF ++F E+ +
Sbjct: 1151 LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIK 1210
Query: 551 CSRPNRGGCEQRCLN----TLGSYKCSCDPGYELAPDKR----------------RCEAA 590
C P + + S SCDPGY L + C A
Sbjct: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAE 1270
Query: 591 CGGFLT-KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
CGG + +++G + SPG+P Y N NCIW + A I L F F+TE +D +
Sbjct: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHDVL 1326
Query: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF-----FSDK 704
+ G L + G P+ + S +N++ ++F +D SK+GF F S
Sbjct: 1327 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCN 1386
Query: 705 DECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE---------------AGCD 748
D NG D S QC G+ L + C + A C
Sbjct: 1387 DPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCG 1446
Query: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVF 808
+T SG I SPN+P+ YP KEC W ++ +P + + L F ++E YD L ++
Sbjct: 1447 GDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDFLHIY 1502
Query: 809 DGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
DGRD+ +P++G F GS+ P + ++ + +FL F SD SV GF
Sbjct: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGF 1546
Score = 190 bits (483), Expect = 5e-48
Identities = 142/479 (29%), Positives = 215/479 (44%), Gaps = 71/479 (14%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGGD+ G I SPNYP+ Y P K C W++ VS + + L F F +E YD+
Sbjct: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDF 1498
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
L + DG S LIG + G + P I+S+S+ L+L F SD S++ AGF +++ + E C
Sbjct: 1499 LHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESC 1558
Query: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYE----------LAPDKRR--------C 587
P R G + + +++ Y C GYE L PD + C
Sbjct: 1559 FDPGSIKNGTRVGSDLKLGSSVTYY---CHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC 1615
Query: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
A CGG +G + SP +P+ Y + C++ + P Y + QF FF T NDV
Sbjct: 1616 TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDV---- 1671
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVIT-SQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
VEV G + S+L GS E + + N + ++F + +GF HF
Sbjct: 1672 -VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGF--HFVYQAVP 1728
Query: 702 -SDKDECS---KDNGGCQQDCVNTFGSY-ECQCRSGFVLHDNKH-DCKEAG--------- 746
+ +CS + G + + G+ +C SG+ L + +C
Sbjct: 1729 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 1788
Query: 747 -------CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPE 799
C +T GTI SP +P+ Y + C W I G +++ + E
Sbjct: 1789 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 1846
Query: 800 CAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
+D LEVFDG D +LG F G+ P + +T ++++L FYSD SV GF + T
Sbjct: 1847 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
Score = 182 bits (463), Expect = 1e-45
Identities = 143/482 (29%), Positives = 216/482 (44%), Gaps = 62/482 (12%)
Query: 417 RSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLT 476
+ ++ W K V+ C + G + SPNYP+DY C+W I + L
Sbjct: 562 QKNNQWSAKKPGCVFS--CFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLA 619
Query: 477 FQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSIN 536
F ++E +D+L ++DG + + ++G + G + P I S+ L+F +D S
Sbjct: 620 FNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTG 675
Query: 537 KAGFAVNF--FKEVDECSRPN------RGG------------CEQRCLNTLGSYKCSC-- 574
K GF + F F+ +EC P R G C++ L T GS +C
Sbjct: 676 KRGFNITFTTFRH-NECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVL 734
Query: 575 -DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF 633
+ RCEA CGG LT +G+I SPGWP Y +C W + A Y I + F
Sbjct: 735 KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITF 794
Query: 634 DFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK 693
D F+TE N YD +EVR G T + L G + G++ P+ + S N + + F +D + S
Sbjct: 795 DRFKTEVN----YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
Query: 694 KGFKAHFFS---DKDECSKD----NGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCK-- 743
GF+ + + D C NG + C SG+ L D + +C+
Sbjct: 851 IGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPN 910
Query: 744 ----------EAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMD 793
EA C + +SGTI SP +PD YP+ CTW I ++ G V TF
Sbjct: 911 FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH 970
Query: 794 IESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMF---LRFYSDNSVQRK 850
+ES +D+L + + P L + GS+ P P+ A F +RF SD S+ +
Sbjct: 971 LES----GHDYLLITENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYE 1025
Query: 851 GF 852
GF
Sbjct: 1026 GF 1027
Score = 176 bits (447), Expect = 7e-44
Identities = 174/678 (25%), Positives = 265/678 (39%), Gaps = 163/678 (24%)
Query: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESS 503
G ++SP +P Y C W I E + L FQSF +E +D L V DG +
Sbjct: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLSVFDGPPQPE 90
Query: 504 TLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEV---DECSRPNR--GG 558
L R G++ P I S ++ L L+ +SD +++ GF + EV C P R G
Sbjct: 91 NLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATY--EVLPSHTCGNPGRLPNG 148
Query: 559 CEQRCLNTLGS---YKCS------------CDPGYELAPD------KRRCEAACGGFLTK 597
+Q LG Y C+ C G E + R + ACGG L
Sbjct: 149 IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRG 208
Query: 598 LNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTA 657
+G I+SP +P EY N +C W ++A I+L F F+ E YDF+EV T
Sbjct: 209 QSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLEVTG--TE 262
Query: 658 DSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKD----------EC 707
S L F G+ P + S N +R+ F SD ++GF A + K
Sbjct: 263 GSSLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMP 320
Query: 708 SKDNGG----------------CQQDCVNTFG-----------SYECQCRSGFVLH---- 736
SKDN C + G S + C G+ L
Sbjct: 321 SKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKR 380
Query: 737 --------------DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISS-TP 781
D++ C+ CD + SG ITSPN+P +Y + C W I++ P
Sbjct: 381 ITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNP 440
Query: 782 GHRVKLTFMEMDIESQPECAYDHLEVFDGRDA--KAPVLGRFCGSKKPEPVLATGSRMFL 839
+KL F E D+E YD L V DG + VL G+ P+ +++T +M+L
Sbjct: 441 SKVIKLAFEEFDLER----GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWL 496
Query: 840 RFYSDNSVQRKG------------------------------------FQASHATECGGQ 863
F +D S G F+ A E GQ
Sbjct: 497 LFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQ 556
Query: 864 VRADVKTKDLYSHAQFG-----------------DNNYP----GGVDCEWVIVAEEGYGV 902
+ + +S + G NYP + C W+I+A +
Sbjct: 557 KAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRI 616
Query: 903 ELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDD 962
L F +VE + +D++ + DG + AP LG + G+ P + S+G ++F +D
Sbjct: 617 HLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDH 672
Query: 963 TITKKGFHLRYTSTKFQD 980
+ K+GF++ +T+ + +
Sbjct: 673 STGKRGFNITFTTFRHNE 690
Score = 176 bits (445), Expect = 1e-43
Identities = 203/839 (24%), Positives = 316/839 (37%), Gaps = 190/839 (22%)
Query: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
L +G + + +C A CG L +G SP +P Y + C W I PG I +
Sbjct: 734 LKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
Query: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
F D +++ + YD +EVRDG APL G + G+++P+ ++ST + L++ F + +
Sbjct: 794 F---DRFKTEVN-YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHS 849
Query: 424 GKGFFAVYEAIC------------------GGD--------VKKDYGHIQSPNYPDDYRP 457
GF YE I G D D G+ S P + P
Sbjct: 850 DIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEP 909
Query: 458 S-----------KVCIWRIQVSEGFHVGLTFQSFEIER---------------------- 484
+ +C IQ S G + F F
Sbjct: 910 NFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF 969
Query: 485 HDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFA 541
H +DYL + + S + L + G P I + + ++F+SD S++ GF
Sbjct: 970 HLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFN 1028
Query: 542 VNFFK-EVDECSRPN------RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------- 585
+ F + +++ C P R G + +TL SC PGY L R
Sbjct: 1029 ITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRR 1085
Query: 586 -------RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET 638
RC A CG +T G++ SP +P Y N CI+ + I L+ FE
Sbjct: 1086 LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFEL 1145
Query: 639 EGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFK 697
DV K V G ++L G F SE V + S +++ ++F +D + KGF+
Sbjct: 1146 SEGDVLK-----VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE 1200
Query: 698 AHFFSDK-----------------DECSKDNGGCQQDC---VNTFGSYECQCRSG-FVLH 736
HF S + DE C + GS E C SG
Sbjct: 1201 LHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTW 1260
Query: 737 DNKHDCKEAGCDHKVT-STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIE 795
D A C V SG + SP +P Y C W I + G + L F+ D E
Sbjct: 1261 DRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTE 1320
Query: 796 SQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKG---- 851
+D L ++DG +L G P+ + +T + + L+F +D ++G
Sbjct: 1321 E----VHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQ 1376
Query: 852 FQASHATEC----------------------------GGQVRADVKTKDLYSHAQF---- 879
F S AT C G ++ + + +F
Sbjct: 1377 FSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQP 1436
Query: 880 ----------GDNNYPGGV--------------DCEWVIVAEEGYGVELVFQTFEVEEET 915
GD P GV +C+W + Y + LVF F +E
Sbjct: 1437 SPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP-- 1494
Query: 916 DCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYT 974
GYD++ ++DG DS +P +G + GS P + S+ +S+ + F SD +++ GF + YT
Sbjct: 1495 --GYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
Score = 172 bits (435), Expect = 2e-42
Identities = 137/484 (28%), Positives = 204/484 (42%), Gaps = 73/484 (15%)
Query: 433 AICGGDVKKDY-GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
A CGG V+ + G + SP YP Y + CIW I+ G +GL F F+ E +D
Sbjct: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 1324
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
L + DG ES L+ G P D+ ST + + L+F +D +K GFA+ F V
Sbjct: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF--SVSTA 1382
Query: 552 SRPNRGGCEQRCLNTLGSYKCS------CDPGYELA-----------------PDKRRCE 588
+ N G Q + S++ CDPGY L P C
Sbjct: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
Query: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
A CGG LT +G I SP +P+ YPP K C W++ Y I+L F+ F E YDF
Sbjct: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDF 1498
Query: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
+ + G + S L G F GS+ P I S N++ + F+SD +VS GF + + E
Sbjct: 1499 LHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESC 1558
Query: 709 KDNGGCQQD-------------CVNTFGSYECQCRS---------GFVLHDNKHDCKEAG 746
D G + G YE + S G + +N A
Sbjct: 1559 FDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAP 1618
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRV--KLTFMEMDIESQPECAYDH 804
C + + G + SPN+P Y S + C + ++ + V + F + D
Sbjct: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-------DV 1671
Query: 805 LEVFDGRDAKAPVLGRFCGSKKPEPV-LATGSRMFLRFYSDNSVQRKGFQ-------ASH 856
+EV DG + +L GS E + LAT +++ ++F + +GF +
Sbjct: 1672 VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTS 1731
Query: 857 ATEC 860
AT+C
Sbjct: 1732 ATQC 1735
Score = 169 bits (428), Expect = 1e-41
Identities = 133/476 (27%), Positives = 206/476 (43%), Gaps = 65/476 (13%)
Query: 430 VYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCA 489
V A CGG G + SPNYP +Y ++C++ + V + + V F F +
Sbjct: 1614 VCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TAL 1668
Query: 490 YDYLEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEV 548
D +EV DGHS+ S L+ G + + +TS+++ +KF + G GF ++ V
Sbjct: 1669 NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHF-VYQAV 1727
Query: 549 DECSRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR--------------- 585
S E R LGS + C+ GY L
Sbjct: 1728 PRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNV 1787
Query: 586 ---RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642
C CGG LT+ G+I SPG+P+ Y + NC+W++V P I +Q F TE N
Sbjct: 1788 SAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN- 1846
Query: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF-- 700
+D +EV G + G F G+ P ++ S N + + F SD +VS GF +
Sbjct: 1847 ---WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
Query: 701 --FSDKDECSKDNGGC---QQDCVNTFGSYECQCRSGFVLHDNKH-DCKE---------- 744
S E + + G ++ VN S+ QC G+ L + H C
Sbjct: 1904 VGLSSCPEPAVPSNGVKTGERYLVNDVVSF--QCEPGYALQGHAHISCMPGTVRRWNYPP 1961
Query: 745 ----AGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPEC 800
A C V G I SP +P YPS +C+W I+ G + F+ E
Sbjct: 1962 PLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN--- 2018
Query: 801 AYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
+D++E+ +G + ++GRF GS+ P +L+T + F+SD+S R GF+ +
Sbjct: 2019 -HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
Score = 164 bits (416), Expect = 3e-40
Identities = 211/867 (24%), Positives = 328/867 (37%), Gaps = 238/867 (27%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDL------------ 369
C L G SP +P GY + +C W I+ +I L F S L
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
Query: 370 ------YRSRLCWY-------------------DYVEVRDGFWRKAP-LRGRFCGS--KL 401
R+RL + DY GF L CG+ +L
Sbjct: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
Query: 402 PEPIVSTDS-RLWVEFRSSSNWVGKGFFAVYEAI-------------------------C 435
P I + L + R S N GFF A+ C
Sbjct: 146 PNGIQQGSTFNLGDKVRYSCNL---GFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
Query: 436 GGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEV 495
GG ++ G I SP++P +Y + C W I G + L F F++E YD+LEV
Sbjct: 203 GGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED----GYDFLEV 258
Query: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFF--KEVDECSR 553
+E S+L + G P + S+ + L L F SDG+ + GF+ + K+++ SR
Sbjct: 259 TG--TEGSSLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSR 314
Query: 554 -----PNRGGCEQRCLNT----------------------------LGS-YKCSCDPGYE 579
P++ ++ + T LGS + +C+ GY+
Sbjct: 315 GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYD 374
Query: 580 LAPDKRR------------------CEAA-CGGFLTKLNGSITSPGWPKEYPPNKNCIWQ 620
L KR C A C L +G ITSP +P +Y N +C+W
Sbjct: 375 LQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWI 434
Query: 621 LVAPTQYR-ISLQFDFFETEGNDVCKYDFVEVRSG-LTADSK-LHGKFCGSEKPEVITSQ 677
+ A + I L F+ F+ E YD + V G D K + G+ P++I S
Sbjct: 435 ITALNPSKVIKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVST 490
Query: 678 YNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYE----------- 726
+ M + F++D + S GFKA + +E + G C + +G E
Sbjct: 491 NHQMWLLFQTDGSGSSLGFKASY----EEI--EQGSCGDPGIPAYGRREGSRFHHGDTLK 544
Query: 727 CQCRSGFVL---------HDNKHDCKEAGCDHKV----TSTSGTITSPNWPDKYPSKKEC 773
+C+ F L +N+ K+ GC TS SG + SPN+P+ Y + C
Sbjct: 545 FECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHC 604
Query: 774 TWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLAT 833
W I + P R+ L F ++D+E Q +D L + DG A+APVLG F G++ P + ++
Sbjct: 605 VWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSS 660
Query: 834 GSRMFLRFYSDNSVQRKGFQASHAT----ECGGQVRADVKTKDLYSHAQFG-------DN 882
G L F +D+S ++GF + T EC V K Q G D
Sbjct: 661 GHVARLEFQTDHSTGKRGFNITFTTFRHNEC-PDPGVPVNGKRFGDSLQLGSSISFLCDE 719
Query: 883 NYPGGVDCEWV-IVAEEGYGVELVFQTFEVEEETDCG----------------------- 918
+ G E + V +EG +V+ + + E CG
Sbjct: 720 GFLGTQGSETITCVLKEG---SVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDAL 776
Query: 919 -----------------YDYMELFDGYDS---------TAPRLGRYCGSGPPEEVYSAGD 952
+D + YD+ +AP +G Y G+ P+ + S +
Sbjct: 777 SCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSN 836
Query: 953 SVLVKFHSDDTITKKGFHLRYTSTKFQ 979
+ + F +D + + GF LRY + Q
Sbjct: 837 YLYLLFSTDKSHSDIGFQLRYETITLQ 863
Score = 93.6 bits (231), Expect = 8e-19
Identities = 75/294 (25%), Positives = 125/294 (42%), Gaps = 34/294 (11%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
E CGG++ G + SP +P Y S+ C+W I V G V L + E + D
Sbjct: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGD 2234
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
++ + DG +++ +G + ++S+S+++ LKF D + FA+ F + +
Sbjct: 2235 FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTK 2293
Query: 551 CSRPN-----RGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEA 589
C P E N + C PG+ L ++ CE
Sbjct: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
Query: 590 AC--GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
C LT G I S +P YP + C W + Y ISL ++F +E +YD
Sbjct: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYD 2409
Query: 648 FVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
E+ G + S L G+ P ++TS N++ + + SD+ ++KGFK +
Sbjct: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
Score = 70.5 bits (171), Expect = 7e-12
Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 740 HDCKEAG--CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQ 797
H + AG C ++ +GT+ SP +P YP+ CTW I++ HR++L F +E
Sbjct: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED 76
Query: 798 PECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
+D L VFDG + R G + P +++ + + LR SD +V +GF A++
Sbjct: 77 ----FDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATY 131
Score = 70.1 bits (170), Expect = 1e-11
Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRT-RLSKGDIAQARKLYKCPACGETLQDST 330
Y R SR DT+ K+E +GQ+ K + A+K +C +
Sbjct: 529 YGRREGSRFHHGDTL--KFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPS 586
Query: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
G SP YP Y H+HCVW I P +I L F +D+ +D++ ++DG +A
Sbjct: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEA 642
Query: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGF 427
P+ G F G++LP I S+ +EF++ + +GF
Sbjct: 643 PVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGF 679
Score = 66.6 bits (161), Expect = 1e-10
Identities = 34/111 (30%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG T+++ G SP +P Y ++M C W+I++ G + F + + +DY+E
Sbjct: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIE 2023
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
+R+G + + + GRF GS+LP ++ST V F S + GF Y+
Sbjct: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
Score = 66.6 bits (161), Expect = 1e-10
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NYP +DC W I G+G + F F E +DY+E+ +G T+ +GR+ GS
Sbjct: 1987 NYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIRNGPYETSRMMGRFSGSE 2042
Query: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHS 984
P + S V FHSD + + GF L Y + + S
Sbjct: 2043 LPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISS 2084
Score = 61.2 bits (147), Expect = 5e-09
Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 16/116 (13%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACG TL+ +G SSP +P+ Y + C W I G+ I L F L YD++
Sbjct: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFL 256
Query: 381 EVR----DGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
EV W F G+ LP P++S+ + L + F S N +GF A Y+
Sbjct: 257 EVTGTEGSSLW--------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
Score = 59.3 bits (142), Expect = 2e-08
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Query: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRS 372
R + + C L+ +G +SP +P Y + HCVW I ++ P + I L F DL R
Sbjct: 397 RPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG 456
Query: 373 RLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
YD + V DG + + G+ +P+ IVST+ ++W+ F++ + GF A
Sbjct: 457 ----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKAS 512
Query: 431 YEAI----CGGDVKKDYGHIQSPNY 451
YE I CG YG + +
Sbjct: 513 YEEIEQGSCGDPGIPAYGRREGSRF 537
Score = 57.0 bits (136), Expect = 9e-08
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L + G SP +P Y ++CVW+I V G I + S ++ +D +E
Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
V DG + G F G+ +P + ST ++L++ F S + GF Y+ +
Sbjct: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
L KC CG + S G SP +P+ YS+ CVW I+V G + LN + L S
Sbjct: 2175 LPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG- 2233
Query: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
D++ + DG + AP G F S + + S+ +++ ++F + G FA+
Sbjct: 2234 ---DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA--ATGGIFAI 2284
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 13/126 (10%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG +R + S F + Y DC W I+AE G + LVF F++E+ GY
Sbjct: 202 CGGTLRGQ---SGIISSPHF-PSEYHNNADCTWTILAELGDTIALVFIDFQLED----GY 253
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
D++E+ S+ + G+ P V S+ + + + F SD ++GF +Y K Q
Sbjct: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY-QVKKQ 308
Query: 980 DTLHSR 985
L SR
Sbjct: 309 IELKSR 314
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 6/116 (5%)
Query: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
CP E L DSTG S YP Y C W + V P I L +++ + S YD
Sbjct: 2355 CPT-NELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL---TVEYFLSEK-QYD 2409
Query: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
E+ DG ++PL G+ P + S+ + +++ + S + KGF Y A
Sbjct: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Score = 44.3 bits (103), Expect = 6e-04
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG S G SP YP Y++ C++ ++V P + ++ F + + L D VE
Sbjct: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTV-PKDYVV--FGQFAFFHTAL--NDVVE 1673
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
V DG + + L GS E + ++T +++ ++F + +GF VY+A+
Sbjct: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
Score = 40.4 bits (93), Expect = 0.008
Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NY +C + I + G G++L + FE+ E D ++++DG +++A LG + S
Sbjct: 1117 NYNNNHECIYSIQTQPGKGIQLKARAFELSEG-----DVLKVYDGNNNSARLLGVFSHSE 1171
Query: 943 -PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
+ S S+ + F +D T KGF L ++S
Sbjct: 1172 MMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
Score = 32.7 bits (73), Expect = 1.7
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 6/92 (6%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NY G C + + + Y V F F D +E+ DG+ + L GS
Sbjct: 1638 NYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-----DVVEVHDGHSQHSRLLSSLSGSH 1692
Query: 943 PPEEV-YSAGDSVLVKFHSDDTITKKGFHLRY 973
E + + + VL+KF + +GFH Y
Sbjct: 1693 TGESLPLATSNQVLIKFSAKGLAPARGFHFVY 1724
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 199 bits (507), Expect = 8e-51
Identities = 121/390 (31%), Positives = 188/390 (48%), Gaps = 56/390 (14%)
Query: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
CGG L+ +G+ +SP +P+ YP N C W +V + L F F+ E +D C +DF+E
Sbjct: 30 CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 89
Query: 651 VRSGLTADS-KLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSK 709
+ +G + D L G+FCG P TS ++ M V F SD V+ GF A + KD C
Sbjct: 90 IYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGY--QKDVC-- 145
Query: 710 DNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPS 769
GG +T SG +TSP +P+ YP+
Sbjct: 146 --GGV------------------------------------LTGLSGVLTSPEYPNNYPN 167
Query: 770 KKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLG-RFCGSKKPE 828
EC W I + VKL F++ +E EC YD++ V G P G +CGS +P
Sbjct: 168 SMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGG---PGPTRGHHYCGSTRPP 224
Query: 829 PVLATGSRMFLRFYSDNSVQRKGFQASH-ATECGGQVRADVKTKDLYSHAQFGDNNYPGG 887
+++ G + + F SD ++ +GF+A + + EC A + +S Q+ ++YP
Sbjct: 225 TLVSLGHELQVVFKSDFNIGGRGFKAYYFSGECQEVYMA---MRGNFSSPQY-PSSYPNN 280
Query: 888 VDCEWVIVAEEGYGVELVFQTFEVEEETD----CGYDYMELFDGYDSTAPRLGRYCGSGP 943
+ C W I GY V++ F ++EE C +D++ FDG AP LG +CG
Sbjct: 281 IRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGHHL 340
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
P V S+ + +L+ H+D + T++GF + Y
Sbjct: 341 PPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
Score = 175 bits (444), Expect = 2e-43
Identities = 118/409 (28%), Positives = 179/409 (43%), Gaps = 53/409 (12%)
Query: 305 LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNF 364
L G AQA + KC G L +GNFSSP +P Y + C W I V G ++L F
Sbjct: 16 LGPGLQAQAMEGVKC---GGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTF 72
Query: 365 TSLDLYRSRLCWYDYVEVRDGFW-RKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
+ DL C +D++E+ +G K L GRFCG P P S+ + V F S +
Sbjct: 73 HAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVA 132
Query: 424 GKGFFAVYEA-ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEI 482
GF A Y+ +CGG + G + SP YP++Y S C W I+ + HV L F F++
Sbjct: 133 SHGFSAGYQKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQV 192
Query: 483 ERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV 542
E ++ C YDY+ V G T YCG +P + S L + F SD +I GF
Sbjct: 193 EGNEECTYDYVAVLGG--PGPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKA 250
Query: 543 NFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSI 602
+F G C++ + G+
Sbjct: 251 YYFS----------GECQE--------------------------------VYMAMRGNF 268
Query: 603 TSPGWPKEYPPNKNCIWQLVAPTQYRISLQF-DFFETEGNDV---CKYDFVEVRSGLTAD 658
+SP +P YP N C W + P Y++ + F D E N + C +D + G + +
Sbjct: 269 SSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEE 328
Query: 659 SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
+ L G +CG P +TS +N + + +D + +++GF + + C
Sbjct: 329 APLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYIGGQLGC 377
Score = 144 bits (364), Expect = 3e-34
Identities = 88/238 (36%), Positives = 121/238 (50%), Gaps = 12/238 (5%)
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
C +++ SG +SPN+P YP EC+W I G V LTF D+E C++D LE
Sbjct: 30 CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 89
Query: 807 VFDGRDA-KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATE-CGGQV 864
+++G K +LGRFCG P P ++ M + F+SD V GF A + + CGG +
Sbjct: 90 IYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQKDVCGGVL 149
Query: 865 R--ADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYM 922
+ V T Y NNYP ++C WVI A V+LVF F+VE +C YDY+
Sbjct: 150 TGLSGVLTSPEY------PNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYV 203
Query: 923 ELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD 980
+ G T R YCGS P + S G + V F SD I +GF Y S + Q+
Sbjct: 204 AVLGGPGPT--RGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSGECQE 259
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 199 bits (505), Expect = 1e-50
Identities = 166/645 (25%), Positives = 272/645 (42%), Gaps = 122/645 (18%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 508 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 563
Query: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 564 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 623
Query: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
C P G E + + C G+EL +K C C
Sbjct: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 683
Query: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 684 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 739
Query: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDEC----- 707
G + +S + G F G+E P +TS + +R+EF++D+++S +GF + + +EC
Sbjct: 740 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 799
Query: 708 --------------SKDNGGCQQDCVNTFGSYECQC--RSGFVLHDNKHDCKEAGCDHKV 751
S + C++ + T G+ C G V+ A C
Sbjct: 800 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHF 859
Query: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
++ SG I SP WP Y C W I + PGH +K+TF Q E YD LEV DG
Sbjct: 860 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF----QTELNYDVLEVHDGP 915
Query: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA----------------- 854
+ +P+LG + G++ P+ + ++ + ++L F +DNS GF+
Sbjct: 916 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 975
Query: 855 -------SHATECGGQVRADVKTKDLYSHAQ---------------------FGDNNYPG 886
H G V + SH + GD P
Sbjct: 976 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 1035
Query: 887 G--------------VDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTA 932
G ++C W + G GV+ F TF +E+ +DY+ + + T
Sbjct: 1036 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSFTQ 1091
Query: 933 PRLGRYCGSGPPEEVYS---AGDSVLVKFHSDDTITKKGFHLRYT 974
P L R GS P + + ++F SD +I+ +GF++ ++
Sbjct: 1092 P-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
Score = 196 bits (498), Expect = 9e-50
Identities = 134/452 (29%), Positives = 218/452 (48%), Gaps = 56/452 (12%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 2014
Query: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
P ++ + + S++C D GY L P +R C A CG
Sbjct: 2015 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2072
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 2073 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2128
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD-- 710
SG + S + G+ G + P + S + + F SD + +K+GF + + + + D
Sbjct: 2129 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPR 2188
Query: 711 ---NGGCQQDCVNTFGSYECQCRSGFVLHDNK-----HDCK----------EAGCDHKVT 752
NG + + +C G+ L N H EA C +T
Sbjct: 2189 PFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNIT 2248
Query: 753 STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRD 812
+ +GTI SP +PD+YP+ ++C W + PG+ + + F + Q E YD + V+DG D
Sbjct: 2249 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL----QTEPIYDFITVWDGPD 2304
Query: 813 AKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
+P +G+F G+ E V +T +++ ++F+SD
Sbjct: 2305 QNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2336
Score = 192 bits (489), Expect = 1e-48
Identities = 174/648 (26%), Positives = 270/648 (41%), Gaps = 126/648 (19%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG + G + SPNYP +Y + CI+ IQV G + ++ ++F + + D
Sbjct: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1253
Query: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
L++ DG +++ L+G + G + STS++LWL+F SD GF + + E+
Sbjct: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
Query: 551 CSRPNRGGCEQRCLNTLGSYKCS-----CDPGYEL--------APDKRR--------CEA 589
C P + ++ G + S C+PGY L +RR C A
Sbjct: 1314 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
Query: 590 ACGG-FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
CGG F + +G I SPG+P Y N C+W + +SLQF F+TE + +D
Sbjct: 1373 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1428
Query: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
+ V G + L + GS PE I S N + ++F +D +SK GF F S
Sbjct: 1429 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1488
Query: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLH-DNKHDCKE---------------AGC 747
+D G N G + QC G+ L + + C + A C
Sbjct: 1489 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
Query: 748 DHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEV 807
+T +SG I SPN+P YP ++C W I+ + + L F+ IE YD L +
Sbjct: 1549 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1604
Query: 808 FDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATEC------- 860
+DG D+ +P++G F SK PE + ++ + M L F SD SV GF + +
Sbjct: 1605 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1664
Query: 861 -----GGQVRADVK---TKDLYSHAQF------------GDNNYPG-------------- 886
G ++ D K T Y A + GD+ PG
Sbjct: 1665 GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGS 1724
Query: 887 --------------------GVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD 926
G +C + I + + V F F+ +D +E++D
Sbjct: 1725 RSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL-----HDVVEVYD 1779
Query: 927 GYDSTAPRLGRYCGSGPPEEV-YSAGDSVLVKFHSDDTITKKGFHLRY 973
G + L GS E + S+G+ + ++F S IT KGFH Y
Sbjct: 1780 GPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
Score = 184 bits (468), Expect = 3e-46
Identities = 145/465 (31%), Positives = 212/465 (45%), Gaps = 56/465 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 2125 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2184
Query: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
RP R G T+G + C PGY L + RCEA CG
Sbjct: 2185 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2244
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 2245 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2300
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG 712
G +S G+F G+ E + S N + ++F SD T S ++ C
Sbjct: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP 2360
Query: 713 GCQQDCVNTFGSYEC------QCRSGFVLHDN-----------KHDCKEAGC------DH 749
+ + +E QC GF L N + D C +
Sbjct: 2361 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2420
Query: 750 KVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFD 809
++G I SP +PD YP+ + C W+IS G+ + + F+E Q E +D L+V+D
Sbjct: 2421 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF---FQTEKEFDVLQVYD 2476
Query: 810 GRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
G + ++PVL G + + G +FL++ +D+ +KGF+
Sbjct: 2477 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2521
Score = 182 bits (463), Expect = 1e-45
Identities = 142/478 (29%), Positives = 212/478 (44%), Gaps = 73/478 (15%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1601
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 1602 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1661
Query: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
P R G + + +T+ Y CD GY L P R C
Sbjct: 1662 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
Query: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 1719 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1774
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVIT-SQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
VEV G T S L GS E + S N + + F S ++ KGF HF
Sbjct: 1775 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1831
Query: 702 -SDKDECSK-DNGGCQQDCVNTFG---SYECQCRSGFVLH------------------DN 738
+ +CS + N F S C G++LH D+
Sbjct: 1832 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1891
Query: 739 KHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP 798
C C +T GTI SP +P+ Y + C W I+ G +++ + E
Sbjct: 1892 LPTCI-VPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1949
Query: 799 ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
+D L+ +DG D AP LG + G+ P + +T + ++L F SD SV GF +
Sbjct: 1950 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 2004
Score = 166 bits (421), Expect = 8e-41
Identities = 132/466 (28%), Positives = 198/466 (42%), Gaps = 59/466 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 1720 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1774
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 1775 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1834
Query: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
S E R +G S C+PGY E P+
Sbjct: 1835 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
Query: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 1895 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1950
Query: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKD 705
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF + + D
Sbjct: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2010
Query: 706 EC----SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE--------------AG 746
C + +G D QC G+ L + H C A
Sbjct: 2011 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2070
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
C ++ SG I SP +P YPS +CTW I+ G V L F+ E+ +D+LE
Sbjct: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDYLE 2126
Query: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
V G + V+GR G + P + +T L F+SD S ++GF
Sbjct: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 2172
Score = 160 bits (406), Expect = 4e-39
Identities = 190/717 (26%), Positives = 294/717 (41%), Gaps = 132/717 (18%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE-------A 433
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 256 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
Query: 434 ICGGDVKK----DYGHIQSPNYPDDYRPSKVCIWRI-QVSEGFHVGLT-FQSFEIERHDS 487
G++++ G I + P D S V I ++SE V +T ++ ++ + S
Sbjct: 312 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 371
Query: 488 CAYDYLEVRDGHSESSTLIGRYC--------------GYEKPDDIKSTSSRLW------- 526
D L ++S+ R+ +K D KS +L+
Sbjct: 372 --KDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 429
Query: 527 -LKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGS-YKCSCDPGYELAPDK 584
+++G I A N + E R G + +LGS + SCD Y L K
Sbjct: 430 KFSILNEGGIKTAS---NLCPDPGEPENGKRIGSD----FSLGSTVQFSCDEDYVLQGAK 482
Query: 585 R-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA-P 624
C+ CG L +G+ TSP +P +Y N C+W + A
Sbjct: 483 SITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVN 542
Query: 625 TQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMR 682
T I + F+ F+ E G D D EV T L G F P++I S + M
Sbjct: 543 TNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDLIVSMSSQMW 598
Query: 683 VEFKSDNTVSKKGFKAHFFSDKDECSKDNG----GCQQ-DCVNTFGSYECQCRSGFVLHD 737
+ ++D +V GFK ++ + E D G G ++ D + +C+ GF L
Sbjct: 599 LHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIG 658
Query: 738 NKH-DCKEAG------------CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHR 784
K C+E C T+ GT+ SP++P+ Y + C W I S PG R
Sbjct: 659 EKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSR 718
Query: 785 VKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
+ L+F + D+ESQ +D L V DG ++P+LG F G++ P + + + L F +D
Sbjct: 719 IHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQAD 774
Query: 845 NSVQRKGFQASHAT----EC---GGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAE 897
+S+ +GF ++ T EC G + A +FGDN G ++ E
Sbjct: 775 HSMSGRGFNITYNTFGHNECPDPGIPINA----------RRFGDNFQLGS---SISVICE 821
Query: 898 EGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCG---SGPPEEVYSAG 951
EG+ +T E T D ++ G P+ G CG S P + S G
Sbjct: 822 EGF-----IKTQGTETITCILMDGKVMWSG---LIPKCGAPCGGHFSAPSGVILSPG 870
Score = 150 bits (379), Expect = 6e-36
Identities = 127/466 (27%), Positives = 200/466 (42%), Gaps = 60/466 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 853 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 908
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-------AVNFF 545
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF VN +
Sbjct: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 968
Query: 546 KEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDK--------------RRCEAAC 591
+D P G + + SCD GY L+ ++ C+A C
Sbjct: 969 SCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 1027
Query: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
GG + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 1028 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLI 1083
Query: 652 RSGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHFFSDKDECS 708
+ L + GS+ P I + Y N R + F SD ++S +GF F E
Sbjct: 1084 TENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1142
Query: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLHDNKH-DCKEAG--------------CD 748
+D G Q F + C SG+ L C G C
Sbjct: 1143 EDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECG 1202
Query: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVF 808
T+ G + SPN+P Y + EC ++I G + ++ + D L+++
Sbjct: 1203 ASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIY 1257
Query: 809 DGRDAKAPVLGRFCG-SKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
DG+D +LG F G S + + +T ++++L F SD +GFQ
Sbjct: 1258 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ 1303
Score = 145 bits (365), Expect = 2e-34
Identities = 133/479 (27%), Positives = 201/479 (41%), Gaps = 64/479 (13%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 1024 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1079
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 1080 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
Query: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
++ C P R G + SC GY L RC
Sbjct: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
Query: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1255
Query: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
+ G + L G F G S + ++S N + +EF SD + +GF+ + S +
Sbjct: 1256 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
Query: 708 SKDNGGCQ-----QDCVNTFGSYECQ-CRSGFVLHDNK----HDCKEAGCDHKVTS---- 753
+D G Q D + GS C G+ LH + + D+ + S
Sbjct: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1373
Query: 754 --------TSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
+SG I SP +P Y + C W I PG+ V L F+ D E+ ++D L
Sbjct: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA----SHDIL 1429
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKG----FQASHATEC 860
V+DG +L GS PE + +T + + ++F +D + + G F +S AT C
Sbjct: 1430 RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1488
Score = 115 bits (287), Expect = 3e-25
Identities = 88/291 (30%), Positives = 126/291 (43%), Gaps = 38/291 (13%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
Query: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
N G + L + + SC GY L + R E
Sbjct: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
Query: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 255
Query: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 256 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 113 bits (282), Expect = 1e-24
Identities = 77/291 (26%), Positives = 129/291 (44%), Gaps = 38/291 (13%)
Query: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
CGG L LNG+I SPG+P YP NC W ++A + RI + F F E +YD++
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 80
Query: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710
+ G + + G P +TS + + SD VS GFK ++ + S
Sbjct: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
Query: 711 NGGCQQDCV------NTFGSYECQCRSGFVLHDNKH------------------DCK-EA 745
N G V + C +G++L + C+ E
Sbjct: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
Query: 746 GCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
C + +SG I+SP++P++Y + +CTW I + PG + L F + +E + YD+L
Sbjct: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
E+ + P G P P+++ + + L F +D++ + +GF A +
Sbjct: 256 EI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 100 bits (250), Expect = 5e-21
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2295
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2353
Query: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
C P +CL +G+ +C G L D C+
Sbjct: 2354 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
Query: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2469
Query: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 2470 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
Score = 97.8 bits (242), Expect = 4e-20
Identities = 76/299 (25%), Positives = 134/299 (44%), Gaps = 68/299 (22%)
Query: 737 DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRV-KLTFMEMDIE 795
D++ CK C + SGT TSPN+P +Y S +C W I++ ++V ++ F E D+
Sbjct: 498 DHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL- 556
Query: 796 SQPECAYDHLEVFDGRDAKAP--VLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
E YD L + DG + P VL GS P+ +++ S+M+L +D SV GF+
Sbjct: 557 ---EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFK 613
Query: 854 ASH----ATECG--GQVRADVKTKDLYSH-------AQFG------------DNN----- 883
++ CG G ++ D +S+ QFG +NN
Sbjct: 614 VNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 673
Query: 884 -----------------------YPGG----VDCEWVIVAEEGYGVELVFQTFEVEEETD 916
YP G ++C W I+++ G + L F F++E +
Sbjct: 674 IPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ-- 731
Query: 917 CGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
+D++ + DG +P LG + G+ P + S + ++F +D +++ +GF++ Y +
Sbjct: 732 --FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
Score = 67.8 bits (164), Expect = 5e-11
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Y ++C W I EG G+++ +F E +D ++ +DG D+ APRLG Y G+
Sbjct: 1919 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 1974
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
P + S +++ + F SD +++ GFHL YT+
Sbjct: 1975 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2006
Score = 66.6 bits (161), Expect = 1e-10
Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NYP +DC W I G+GV L F F T+ +DY+E+ G T+ +GR G
Sbjct: 2090 NYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSSETSTVIGRLSGPQ 2145
Query: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
P ++S + FHSD + K+GFH+ Y + + Q
Sbjct: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
Score = 65.9 bits (159), Expect = 2e-10
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG + A T +YS + YP DC W++ G G+ + F + E Y
Sbjct: 2243 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2294
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGF 969
D++ ++DG D +P++G++ G+ E VYS + +L+KFHSD T GF
Sbjct: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGF 2342
Score = 64.3 bits (155), Expect = 5e-10
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2293
Query: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 2294 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2345
Score = 63.2 bits (152), Expect = 1e-09
Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
YP G +C WVI+AEE +++VFQ+F +EEE YDY+ L+DG+ R G
Sbjct: 45 YPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLSLYDGHPHPTNFRTRLTGFHL 100
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
P V S ++ SD ++ GF + Y
Sbjct: 101 PPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 130
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 451 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 498
Query: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 499 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 557
Query: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 558 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 614
Query: 430 VYEAI----CGGDVKKDYG 444
Y+ I CG YG
Sbjct: 615 NYKEIEKESCGDPGTPLYG 633
Score = 62.4 bits (150), Expect = 2e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1655
Score = 61.2 bits (147), Expect = 5e-09
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1954
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 1955 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
Score = 60.8 bits (146), Expect = 6e-09
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2126
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
Score = 59.7 bits (143), Expect = 1e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2482
Query: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 2483 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2540
Query: 560 EQRCLNTLGS-YKCSCDPGYEL 580
+ L S + +CD G+ L
Sbjct: 2541 ISQTGGQLNSVVRWACDRGFRL 2562
Score = 59.3 bits (142), Expect = 2e-08
Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
YLE+ SE T+ G P I S + L L FV+D + GF+ +
Sbjct: 254 YLEIEG--SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
Query: 552 SRPNRGGCEQRCLNTLGSYKCSCDP 576
+ G E+ T G+ + P
Sbjct: 310 HTTSTGELEEHNRTTTGAIAVASTP 334
Score = 58.5 bits (140), Expect = 3e-08
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 837 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 896
Query: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 897 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 952
Query: 424 GKGFFAVYEAI 434
GF YE++
Sbjct: 953 NNGFKIHYESV 963
Score = 57.4 bits (137), Expect = 7e-08
Identities = 36/113 (31%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG TL+ G SP +P GY +C W I +I + F S L YDY+
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
+ DG R R G LP P+ ST S + S GF YE +
Sbjct: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEEL 133
Score = 57.0 bits (136), Expect = 9e-08
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1251
Query: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 1252 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
Query: 434 ICGGDVKKDYGHIQSPNYP 452
+ H + P P
Sbjct: 1309 F-------ELSHCEDPGIP 1320
Score = 55.1 bits (131), Expect = 3e-07
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 1713 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1769
Query: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 1770 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
Query: 432 EAI 434
+A+
Sbjct: 1828 QAV 1830
Score = 54.7 bits (130), Expect = 4e-07
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 1365 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1424
Query: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 1425 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1478
Score = 50.1 bits (118), Expect = 1e-05
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 12/114 (10%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG +R + + S F N Y DC W IVAE G + L+F F++EE+ Y
Sbjct: 201 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 252
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
DY+E+ + + P G P + S + + + F +D +GF Y
Sbjct: 253 DYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 882 NNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS 941
++YP C W I E+GY + + + F+ E+E +D ++++DG + +P L G
Sbjct: 2436 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2491
Query: 942 -GPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+ S G V +++ +D KKGF +RY
Sbjct: 2492 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2524
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NY +C + I + G G+ + +TF + + D ++++DG D T LG + G+
Sbjct: 1220 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1274
Query: 943 PPEEVYSAGDSVL-VKFHSDDTITKKGFHLRYTS 975
S+ + L ++F+SD T +GF L YTS
Sbjct: 1275 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
Score = 45.1 bits (105), Expect = 3e-04
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 1027 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1082
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 1083 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1120
Score = 38.9 bits (89), Expect = 0.024
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 2416 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2470
Query: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
Query: 437 GDVKKDYGHIQS 448
+G+I S
Sbjct: 2531 TPESPPHGYIIS 2542
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 199 bits (505), Expect = 1e-50
Identities = 166/645 (25%), Positives = 272/645 (42%), Gaps = 122/645 (18%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 444 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 499
Query: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 500 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 559
Query: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
C P G E + + C G+EL +K C C
Sbjct: 560 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 619
Query: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 620 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 675
Query: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDEC----- 707
G + +S + G F G+E P +TS + +R+EF++D+++S +GF + + +EC
Sbjct: 676 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 735
Query: 708 --------------SKDNGGCQQDCVNTFGSYECQC--RSGFVLHDNKHDCKEAGCDHKV 751
S + C++ + T G+ C G V+ A C
Sbjct: 736 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHF 795
Query: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
++ SG I SP WP Y C W I + PGH +K+TF Q E YD LEV DG
Sbjct: 796 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF----QTELNYDVLEVHDGP 851
Query: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA----------------- 854
+ +P+LG + G++ P+ + ++ + ++L F +DNS GF+
Sbjct: 852 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 911
Query: 855 -------SHATECGGQVRADVKTKDLYSHAQ---------------------FGDNNYPG 886
H G V + SH + GD P
Sbjct: 912 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 971
Query: 887 G--------------VDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTA 932
G ++C W + G GV+ F TF +E+ +DY+ + + T
Sbjct: 972 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSFTQ 1027
Query: 933 PRLGRYCGSGPPEEVYS---AGDSVLVKFHSDDTITKKGFHLRYT 974
P L R GS P + + ++F SD +I+ +GF++ ++
Sbjct: 1028 P-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
Score = 196 bits (498), Expect = 9e-50
Identities = 134/452 (29%), Positives = 218/452 (48%), Gaps = 56/452 (12%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 1950
Query: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
P ++ + + S++C D GY L P +R C A CG
Sbjct: 1951 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2008
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 2009 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2064
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD-- 710
SG + S + G+ G + P + S + + F SD + +K+GF + + + + D
Sbjct: 2065 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPR 2124
Query: 711 ---NGGCQQDCVNTFGSYECQCRSGFVLHDNK-----HDCK----------EAGCDHKVT 752
NG + + +C G+ L N H EA C +T
Sbjct: 2125 PFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNIT 2184
Query: 753 STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRD 812
+ +GTI SP +PD+YP+ ++C W + PG+ + + F + Q E YD + V+DG D
Sbjct: 2185 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL----QTEPIYDFITVWDGPD 2240
Query: 813 AKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
+P +G+F G+ E V +T +++ ++F+SD
Sbjct: 2241 QNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2272
Score = 192 bits (489), Expect = 1e-48
Identities = 174/648 (26%), Positives = 270/648 (41%), Gaps = 126/648 (19%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG + G + SPNYP +Y + CI+ IQV G + ++ ++F + + D
Sbjct: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1189
Query: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
L++ DG +++ L+G + G + STS++LWL+F SD GF + + E+
Sbjct: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
Query: 551 CSRPNRGGCEQRCLNTLGSYKCS-----CDPGYEL--------APDKRR--------CEA 589
C P + ++ G + S C+PGY L +RR C A
Sbjct: 1250 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
Query: 590 ACGG-FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
CGG F + +G I SPG+P Y N C+W + +SLQF F+TE + +D
Sbjct: 1309 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1364
Query: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
+ V G + L + GS PE I S N + ++F +D +SK GF F S
Sbjct: 1365 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1424
Query: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLH-DNKHDCKE---------------AGC 747
+D G N G + QC G+ L + + C + A C
Sbjct: 1425 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
Query: 748 DHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEV 807
+T +SG I SPN+P YP ++C W I+ + + L F+ IE YD L +
Sbjct: 1485 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1540
Query: 808 FDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATEC------- 860
+DG D+ +P++G F SK PE + ++ + M L F SD SV GF + +
Sbjct: 1541 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1600
Query: 861 -----GGQVRADVK---TKDLYSHAQF------------GDNNYPG-------------- 886
G ++ D K T Y A + GD+ PG
Sbjct: 1601 GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGS 1660
Query: 887 --------------------GVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD 926
G +C + I + + V F F+ +D +E++D
Sbjct: 1661 RSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL-----HDVVEVYD 1715
Query: 927 GYDSTAPRLGRYCGSGPPEEV-YSAGDSVLVKFHSDDTITKKGFHLRY 973
G + L GS E + S+G+ + ++F S IT KGFH Y
Sbjct: 1716 GPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
Score = 187 bits (475), Expect = 4e-47
Identities = 173/681 (25%), Positives = 275/681 (40%), Gaps = 161/681 (23%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 179
Query: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
N G + L + + SC GY L + R E
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Query: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 295
Query: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF--------- 700
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 296 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFK 351
Query: 701 ------FSDKDECSK----------------------DNGGCQQDCVNTFGSYECQCRSG 732
F KD +K +NG + + + C
Sbjct: 352 SRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDED 411
Query: 733 FVLH------------------DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECT 774
+VL D++ CK C + SGT TSPN+P +Y S +C
Sbjct: 412 YVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCV 471
Query: 775 WAISSTPGHRV-KLTFMEMDIESQPECAYDHLEVFDGRDAKAP--VLGRFCGSKKPEPVL 831
W I++ ++V ++ F E D+ E YD L + DG + P VL GS P+ ++
Sbjct: 472 WVITAVNTNKVIQINFEEFDL----EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIV 527
Query: 832 ATGSRMFLRFYSDNSVQRKGFQASH----ATECG--GQVRADVKTKDLYSH-------AQ 878
+ S+M+L +D SV GF+ ++ CG G ++ D +S+ Q
Sbjct: 528 SMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQ 587
Query: 879 FG------------DNN----------------------------YPGG----VDCEWVI 894
FG +NN YP G ++C W I
Sbjct: 588 FGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI 647
Query: 895 VAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSV 954
+++ G + L F F++E + +D++ + DG +P LG + G+ P + S +
Sbjct: 648 ISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 703
Query: 955 LVKFHSDDTITKKGFHLRYTS 975
++F +D +++ +GF++ Y +
Sbjct: 704 RLEFQADHSMSGRGFNITYNT 724
Score = 184 bits (468), Expect = 3e-46
Identities = 145/465 (31%), Positives = 212/465 (45%), Gaps = 56/465 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
Query: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
RP R G T+G + C PGY L + RCEA CG
Sbjct: 2121 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2180
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 2181 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2236
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG 712
G +S G+F G+ E + S N + ++F SD T S ++ C
Sbjct: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP 2296
Query: 713 GCQQDCVNTFGSYEC------QCRSGFVLHDN-----------KHDCKEAGC------DH 749
+ + +E QC GF L N + D C +
Sbjct: 2297 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2356
Query: 750 KVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFD 809
++G I SP +PD YP+ + C W+IS G+ + + F+E Q E +D L+V+D
Sbjct: 2357 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF---FQTEKEFDVLQVYD 2412
Query: 810 GRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
G + ++PVL G + + G +FL++ +D+ +KGF+
Sbjct: 2413 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2457
Score = 182 bits (463), Expect = 1e-45
Identities = 142/478 (29%), Positives = 212/478 (44%), Gaps = 73/478 (15%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1537
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
Query: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
P R G + + +T+ Y CD GY L P R C
Sbjct: 1598 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
Query: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 1655 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1710
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVIT-SQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
VEV G T S L GS E + S N + + F S ++ KGF HF
Sbjct: 1711 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1767
Query: 702 -SDKDECSK-DNGGCQQDCVNTFG---SYECQCRSGFVLH------------------DN 738
+ +CS + N F S C G++LH D+
Sbjct: 1768 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1827
Query: 739 KHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP 798
C C +T GTI SP +P+ Y + C W I+ G +++ + E
Sbjct: 1828 LPTCI-VPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1885
Query: 799 ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
+D L+ +DG D AP LG + G+ P + +T + ++L F SD SV GF +
Sbjct: 1886 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 1940
Score = 166 bits (421), Expect = 8e-41
Identities = 132/466 (28%), Positives = 198/466 (42%), Gaps = 59/466 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 1656 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1710
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
Query: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
S E R +G S C+PGY E P+
Sbjct: 1771 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
Query: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 1831 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1886
Query: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKD 705
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF + + D
Sbjct: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 1946
Query: 706 EC----SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE--------------AG 746
C + +G D QC G+ L + H C A
Sbjct: 1947 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2006
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
C ++ SG I SP +P YPS +CTW I+ G V L F+ E+ +D+LE
Sbjct: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDYLE 2062
Query: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
V G + V+GR G + P + +T L F+SD S ++GF
Sbjct: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 2108
Score = 152 bits (384), Expect = 1e-36
Identities = 201/779 (25%), Positives = 288/779 (36%), Gaps = 186/779 (23%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG TL+ G SP +P GY +C W I +I + F S L YDY+
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----CGG 437
+ DG R R G LP P+ ST S + S GF YE + CG
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Query: 438 --------------DVKKDYGHIQSPNYPDDYRPSKVCI--------WRIQV-------- 467
DV + Y D P CI W V
Sbjct: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 468 ----SEGFHVGLTFQSFEIERHDSC-------------------------AYDYLEVRDG 498
G ++ SF E H++ YDYLE+
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG- 299
Query: 499 HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVDECSRP-- 554
SE T+ G P I S + L L FV+D + GF+ + K +D SR
Sbjct: 300 -SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
Query: 555 --------------NRGG---CEQRCLN--------------TLGS-YKCSCDPGYELAP 582
N GG C + +LGS + SCD Y L
Sbjct: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
Query: 583 DKR-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA 623
K C+ CG L +G+ TSP +P +Y N C+W + A
Sbjct: 417 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 476
Query: 624 -PTQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNN 680
T I + F+ F+ E G D D EV T L G F P++I S +
Sbjct: 477 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDLIVSMSSQ 532
Query: 681 MRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG----GCQQ-DCVNTFGSYECQCRSGFVL 735
M + ++D +V GFK ++ + E D G G ++ D + +C+ GF L
Sbjct: 533 MWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFEL 592
Query: 736 HDNKH-DCKEAG------------CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPG 782
K C+E C T+ GT+ SP++P+ Y + C W I S PG
Sbjct: 593 IGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPG 652
Query: 783 HRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFY 842
R+ L+F + D+ESQ +D L V DG ++P+LG F G++ P + + + L F
Sbjct: 653 SRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQ 708
Query: 843 SDNSVQRKGFQASHAT----EC---GGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIV 895
+D+S+ +GF ++ T EC G + A +FGDN G ++
Sbjct: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINA----------RRFGDNFQLGS---SISVI 755
Query: 896 AEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCG---SGPPEEVYSAG 951
EEG+ +T E T D ++ G P+ G CG S P + S G
Sbjct: 756 CEEGF-----IKTQGTETITCILMDGKVMWSG---LIPKCGAPCGGHFSAPSGVILSPG 806
Score = 151 bits (381), Expect = 3e-36
Identities = 169/679 (24%), Positives = 265/679 (39%), Gaps = 153/679 (22%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YD 293
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFF--KEVD 549
YLE+ + L G P I S + L L FV+D + GF+ + K +D
Sbjct: 294 YLEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAID 349
Query: 550 ECSRP----------------NRGGCEQR---CLN--------------TLGS-YKCSCD 575
SR N GG + C + +LGS + SCD
Sbjct: 350 FKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCD 409
Query: 576 PGYELAPDKR-RCEA------------------ACGGFLTKLNGSITSPGWPKEYPPNKN 616
Y L K C+ CG L +G+ TSP +P +Y N
Sbjct: 410 EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQ 469
Query: 617 CIWQLVAP-TQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEV 673
C+W + A T I + F+ F+ E G D D EV T L G F P++
Sbjct: 470 CVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDL 525
Query: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG----GCQQ-DCVNTFGSYECQ 728
I S + M + ++D +V GFK ++ + E D G G ++ D + +
Sbjct: 526 IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFE 585
Query: 729 CRSGFVLHDNKHD-CKEAG------------CDHKVTSTSGTITSPNWPDKYPSKKECTW 775
C+ GF L K C+E C T+ GT+ SP++P+ Y + C W
Sbjct: 586 CQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIW 645
Query: 776 AISSTPGHRVKLT-----------FMEMDIESQPECAYDHLEVFDGRD------------ 812
I S PG R+ L+ F+ + PE L F G +
Sbjct: 646 TIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPI--LGTFTGAEVPSHLTSNSHIL 703
Query: 813 -----AKAPVLGR--------FCGSKKPEPVLATGSRMFL-RFYSDNSVQ---RKGFQAS 855
A + GR F ++ P+P + +R F F +S+ +GF +
Sbjct: 704 RLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKT 763
Query: 856 HATE-------------------CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVA 896
TE CG + Y ++CEWVI A
Sbjct: 764 QGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEA 823
Query: 897 EEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLV 956
E G+ +++ F+ F+ T+ YD +E+ DG + +P LG Y G+ P+ ++S+ + + +
Sbjct: 824 EPGHSIKITFERFQ----TELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYL 879
Query: 957 KFHSDDTITKKGFHLRYTS 975
F +D++ + GF + Y S
Sbjct: 880 LFTTDNSRSNNGFKIHYES 898
Score = 150 bits (379), Expect = 6e-36
Identities = 127/466 (27%), Positives = 200/466 (42%), Gaps = 60/466 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 789 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 844
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-------AVNFF 545
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF VN +
Sbjct: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 904
Query: 546 KEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDK--------------RRCEAAC 591
+D P G + + SCD GY L+ ++ C+A C
Sbjct: 905 SCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 963
Query: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
GG + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLI 1019
Query: 652 RSGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHFFSDKDECS 708
+ L + GS+ P I + Y N R + F SD ++S +GF F E
Sbjct: 1020 TENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1078
Query: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLHDNKH-DCKEAG--------------CD 748
+D G Q F + C SG+ L C G C
Sbjct: 1079 EDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECG 1138
Query: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVF 808
T+ G + SPN+P Y + EC ++I G + ++ + D L+++
Sbjct: 1139 ASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIY 1193
Query: 809 DGRDAKAPVLGRFCG-SKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
DG+D +LG F G S + + +T ++++L F SD +GFQ
Sbjct: 1194 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ 1239
Score = 145 bits (365), Expect = 2e-34
Identities = 133/479 (27%), Positives = 201/479 (41%), Gaps = 64/479 (13%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 960 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1015
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 1016 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
Query: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
++ C P R G + SC GY L RC
Sbjct: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
Query: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1191
Query: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
+ G + L G F G S + ++S N + +EF SD + +GF+ + S +
Sbjct: 1192 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
Query: 708 SKDNGGCQ-----QDCVNTFGSYECQ-CRSGFVLHDNK----HDCKEAGCDHKVTS---- 753
+D G Q D + GS C G+ LH + + D+ + S
Sbjct: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1309
Query: 754 --------TSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
+SG I SP +P Y + C W I PG+ V L F+ D E+ ++D L
Sbjct: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA----SHDIL 1365
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKG----FQASHATEC 860
V+DG +L GS PE + +T + + ++F +D + + G F +S AT C
Sbjct: 1366 RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1424
Score = 100 bits (250), Expect = 5e-21
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 2176 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2231
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 2232 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2289
Query: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
C P +CL +G+ +C G L D C+
Sbjct: 2290 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
Query: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2405
Query: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 2406 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
Score = 67.8 bits (164), Expect = 5e-11
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Y ++C W I EG G+++ +F E +D ++ +DG D+ APRLG Y G+
Sbjct: 1855 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 1910
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
P + S +++ + F SD +++ GFHL YT+
Sbjct: 1911 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 1942
Score = 67.4 bits (163), Expect = 6e-11
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 66.6 bits (161), Expect = 1e-10
Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NYP +DC W I G+GV L F F T+ +DY+E+ G T+ +GR G
Sbjct: 2026 NYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSSETSTVIGRLSGPQ 2081
Query: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
P ++S + FHSD + K+GFH+ Y + + Q
Sbjct: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
Score = 65.9 bits (159), Expect = 2e-10
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG + A T +YS + YP DC W++ G G+ + F + E Y
Sbjct: 2179 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2230
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGF 969
D++ ++DG D +P++G++ G+ E VYS + +L+KFHSD T GF
Sbjct: 2231 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGF 2278
Score = 64.3 bits (155), Expect = 5e-10
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 2172 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2229
Query: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 2230 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2281
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 387 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 434
Query: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 435 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 493
Query: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 494 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
Query: 430 VYEAI----CGGDVKKDYG 444
Y+ I CG YG
Sbjct: 551 NYKEIEKESCGDPGTPLYG 569
Score = 62.4 bits (150), Expect = 2e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
Score = 61.2 bits (147), Expect = 5e-09
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
Score = 60.8 bits (146), Expect = 6e-09
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2062
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
Score = 59.7 bits (143), Expect = 1e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2418
Query: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 2419 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2476
Query: 560 EQRCLNTLGS-YKCSCDPGYEL 580
+ L S + +CD G+ L
Sbjct: 2477 ISQTGGQLNSVVRWACDRGFRL 2498
Score = 58.5 bits (140), Expect = 3e-08
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 773 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 832
Query: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 833 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
Query: 424 GKGFFAVYEAI 434
GF YE++
Sbjct: 889 NNGFKIHYESV 899
Score = 57.0 bits (136), Expect = 9e-08
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1187
Query: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 1188 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
Query: 434 ICGGDVKKDYGHIQSPNYP 452
+ H + P P
Sbjct: 1245 F-------ELSHCEDPGIP 1256
Score = 55.1 bits (131), Expect = 3e-07
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 1649 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1705
Query: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 1706 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
Query: 432 EAI 434
+A+
Sbjct: 1764 QAV 1766
Score = 54.7 bits (130), Expect = 4e-07
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 1301 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1360
Query: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 1361 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1414
Score = 50.8 bits (120), Expect = 6e-06
Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 12/121 (9%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG +R + + S F N Y DC W IVAE G + L+F F++EE+ Y
Sbjct: 241 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 292
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
DY+E+ + + P G P + S + + + F +D +GF Y K
Sbjct: 293 DYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
Query: 980 D 980
D
Sbjct: 349 D 349
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 882 NNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS 941
++YP C W I E+GY + + + F+ E+E +D ++++DG + +P L G
Sbjct: 2372 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2427
Query: 942 -GPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+ S G V +++ +D KKGF +RY
Sbjct: 2428 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NY +C + I + G G+ + +TF + + D ++++DG D T LG + G+
Sbjct: 1156 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1210
Query: 943 PPEEVYSAGDSVL-VKFHSDDTITKKGFHLRYTS 975
S+ + L ++F+SD T +GF L YTS
Sbjct: 1211 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
Score = 45.1 bits (105), Expect = 3e-04
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 963 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1018
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 1019 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1056
Score = 38.9 bits (89), Expect = 0.024
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 2352 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2406
Query: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2466
Query: 437 GDVKKDYGHIQS 448
+G+I S
Sbjct: 2467 TPESPPHGYIIS 2478
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 199 bits (505), Expect = 1e-50
Identities = 166/645 (25%), Positives = 272/645 (42%), Gaps = 122/645 (18%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 548 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 603
Query: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 604 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 663
Query: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
C P G E + + C G+EL +K C C
Sbjct: 664 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 723
Query: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 724 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 779
Query: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDEC----- 707
G + +S + G F G+E P +TS + +R+EF++D+++S +GF + + +EC
Sbjct: 780 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 839
Query: 708 --------------SKDNGGCQQDCVNTFGSYECQC--RSGFVLHDNKHDCKEAGCDHKV 751
S + C++ + T G+ C G V+ A C
Sbjct: 840 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHF 899
Query: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
++ SG I SP WP Y C W I + PGH +K+TF Q E YD LEV DG
Sbjct: 900 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF----QTELNYDVLEVHDGP 955
Query: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA----------------- 854
+ +P+LG + G++ P+ + ++ + ++L F +DNS GF+
Sbjct: 956 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 1015
Query: 855 -------SHATECGGQVRADVKTKDLYSHAQ---------------------FGDNNYPG 886
H G V + SH + GD P
Sbjct: 1016 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 1075
Query: 887 G--------------VDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTA 932
G ++C W + G GV+ F TF +E+ +DY+ + + T
Sbjct: 1076 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSFTQ 1131
Query: 933 PRLGRYCGSGPPEEVYS---AGDSVLVKFHSDDTITKKGFHLRYT 974
P L R GS P + + ++F SD +I+ +GF++ ++
Sbjct: 1132 P-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1175
Score = 196 bits (498), Expect = 9e-50
Identities = 134/452 (29%), Positives = 218/452 (48%), Gaps = 56/452 (12%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 1939 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1994
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 1995 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 2054
Query: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
P ++ + + S++C D GY L P +R C A CG
Sbjct: 2055 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2112
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 2113 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2168
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD-- 710
SG + S + G+ G + P + S + + F SD + +K+GF + + + + D
Sbjct: 2169 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPR 2228
Query: 711 ---NGGCQQDCVNTFGSYECQCRSGFVLHDNK-----HDCK----------EAGCDHKVT 752
NG + + +C G+ L N H EA C +T
Sbjct: 2229 PFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNIT 2288
Query: 753 STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRD 812
+ +GTI SP +PD+YP+ ++C W + PG+ + + F + Q E YD + V+DG D
Sbjct: 2289 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL----QTEPIYDFITVWDGPD 2344
Query: 813 AKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
+P +G+F G+ E V +T +++ ++F+SD
Sbjct: 2345 QNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2376
Score = 192 bits (489), Expect = 1e-48
Identities = 174/648 (26%), Positives = 270/648 (41%), Gaps = 126/648 (19%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG + G + SPNYP +Y + CI+ IQV G + ++ ++F + + D
Sbjct: 1239 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1293
Query: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
L++ DG +++ L+G + G + STS++LWL+F SD GF + + E+
Sbjct: 1294 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1353
Query: 551 CSRPNRGGCEQRCLNTLGSYKCS-----CDPGYEL--------APDKRR--------CEA 589
C P + ++ G + S C+PGY L +RR C A
Sbjct: 1354 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1412
Query: 590 ACGG-FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
CGG F + +G I SPG+P Y N C+W + +SLQF F+TE + +D
Sbjct: 1413 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1468
Query: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
+ V G + L + GS PE I S N + ++F +D +SK GF F S
Sbjct: 1469 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1528
Query: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLH-DNKHDCKE---------------AGC 747
+D G N G + QC G+ L + + C + A C
Sbjct: 1529 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1588
Query: 748 DHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEV 807
+T +SG I SPN+P YP ++C W I+ + + L F+ IE YD L +
Sbjct: 1589 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1644
Query: 808 FDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATEC------- 860
+DG D+ +P++G F SK PE + ++ + M L F SD SV GF + +
Sbjct: 1645 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1704
Query: 861 -----GGQVRADVK---TKDLYSHAQF------------GDNNYPG-------------- 886
G ++ D K T Y A + GD+ PG
Sbjct: 1705 GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGS 1764
Query: 887 --------------------GVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD 926
G +C + I + + V F F+ +D +E++D
Sbjct: 1765 RSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL-----HDVVEVYD 1819
Query: 927 GYDSTAPRLGRYCGSGPPEEV-YSAGDSVLVKFHSDDTITKKGFHLRY 973
G + L GS E + S+G+ + ++F S IT KGFH Y
Sbjct: 1820 GPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1867
Score = 184 bits (468), Expect = 3e-46
Identities = 145/465 (31%), Positives = 212/465 (45%), Gaps = 56/465 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 2109 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2164
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 2165 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2224
Query: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
RP R G T+G + C PGY L + RCEA CG
Sbjct: 2225 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2284
Query: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 2285 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2340
Query: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG 712
G +S G+F G+ E + S N + ++F SD T S ++ C
Sbjct: 2341 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP 2400
Query: 713 GCQQDCVNTFGSYEC------QCRSGFVLHDN-----------KHDCKEAGC------DH 749
+ + +E QC GF L N + D C +
Sbjct: 2401 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2460
Query: 750 KVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFD 809
++G I SP +PD YP+ + C W+IS G+ + + F+E Q E +D L+V+D
Sbjct: 2461 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF---FQTEKEFDVLQVYD 2516
Query: 810 GRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
G + ++PVL G + + G +FL++ +D+ +KGF+
Sbjct: 2517 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2561
Score = 182 bits (463), Expect = 1e-45
Identities = 142/478 (29%), Positives = 212/478 (44%), Gaps = 73/478 (15%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 1586 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1641
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 1642 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1701
Query: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
P R G + + +T+ Y CD GY L P R C
Sbjct: 1702 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1758
Query: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 1759 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1814
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVIT-SQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
VEV G T S L GS E + S N + + F S ++ KGF HF
Sbjct: 1815 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1871
Query: 702 -SDKDECSK-DNGGCQQDCVNTFG---SYECQCRSGFVLH------------------DN 738
+ +CS + N F S C G++LH D+
Sbjct: 1872 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1931
Query: 739 KHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP 798
C C +T GTI SP +P+ Y + C W I+ G +++ + E
Sbjct: 1932 LPTCI-VPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1989
Query: 799 ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
+D L+ +DG D AP LG + G+ P + +T + ++L F SD SV GF +
Sbjct: 1990 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 2044
Score = 166 bits (421), Expect = 8e-41
Identities = 132/466 (28%), Positives = 198/466 (42%), Gaps = 59/466 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 1760 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1814
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 1815 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1874
Query: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
S E R +G S C+PGY E P+
Sbjct: 1875 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1934
Query: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 1935 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1990
Query: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKD 705
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF + + D
Sbjct: 1991 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2050
Query: 706 EC----SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE--------------AG 746
C + +G D QC G+ L + H C A
Sbjct: 2051 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2110
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
C ++ SG I SP +P YPS +CTW I+ G V L F+ E+ +D+LE
Sbjct: 2111 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDYLE 2166
Query: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
V G + V+GR G + P + +T L F+SD S ++GF
Sbjct: 2167 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 2212
Score = 160 bits (406), Expect = 4e-39
Identities = 190/717 (26%), Positives = 294/717 (41%), Gaps = 132/717 (18%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE-------A 433
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 351
Query: 434 ICGGDVKK----DYGHIQSPNYPDDYRPSKVCIWRI-QVSEGFHVGLT-FQSFEIERHDS 487
G++++ G I + P D S V I ++SE V +T ++ ++ + S
Sbjct: 352 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 411
Query: 488 CAYDYLEVRDGHSESSTLIGRYC--------------GYEKPDDIKSTSSRLW------- 526
D L ++S+ R+ +K D KS +L+
Sbjct: 412 --KDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 469
Query: 527 -LKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGS-YKCSCDPGYELAPDK 584
+++G I A N + E R G + +LGS + SCD Y L K
Sbjct: 470 KFSILNEGGIKTAS---NLCPDPGEPENGKRIGSD----FSLGSTVQFSCDEDYVLQGAK 522
Query: 585 R-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA-P 624
C+ CG L +G+ TSP +P +Y N C+W + A
Sbjct: 523 SITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVN 582
Query: 625 TQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMR 682
T I + F+ F+ E G D D EV T L G F P++I S + M
Sbjct: 583 TNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDLIVSMSSQMW 638
Query: 683 VEFKSDNTVSKKGFKAHFFSDKDECSKDNG----GCQQ-DCVNTFGSYECQCRSGFVLHD 737
+ ++D +V GFK ++ + E D G G ++ D + +C+ GF L
Sbjct: 639 LHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIG 698
Query: 738 NKH-DCKEAG------------CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHR 784
K C+E C T+ GT+ SP++P+ Y + C W I S PG R
Sbjct: 699 EKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSR 758
Query: 785 VKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
+ L+F + D+ESQ +D L V DG ++P+LG F G++ P + + + L F +D
Sbjct: 759 IHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQAD 814
Query: 845 NSVQRKGFQASHAT----EC---GGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAE 897
+S+ +GF ++ T EC G + A +FGDN G ++ E
Sbjct: 815 HSMSGRGFNITYNTFGHNECPDPGIPINA----------RRFGDNFQLGS---SISVICE 861
Query: 898 EGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCG---SGPPEEVYSAG 951
EG+ +T E T D ++ G P+ G CG S P + S G
Sbjct: 862 EGF-----IKTQGTETITCILMDGKVMWSG---LIPKCGAPCGGHFSAPSGVILSPG 910
Score = 150 bits (379), Expect = 6e-36
Identities = 127/466 (27%), Positives = 200/466 (42%), Gaps = 60/466 (12%)
Query: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 893 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 948
Query: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-------AVNFF 545
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF VN +
Sbjct: 949 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 1008
Query: 546 KEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDK--------------RRCEAAC 591
+D P G + + SCD GY L+ ++ C+A C
Sbjct: 1009 SCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 1067
Query: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
GG + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 1068 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLI 1123
Query: 652 RSGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHFFSDKDECS 708
+ L + GS+ P I + Y N R + F SD ++S +GF F E
Sbjct: 1124 TENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1182
Query: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLHDNKH-DCKEAG--------------CD 748
+D G Q F + C SG+ L C G C
Sbjct: 1183 EDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECG 1242
Query: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVF 808
T+ G + SPN+P Y + EC ++I G + ++ + D L+++
Sbjct: 1243 ASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIY 1297
Query: 809 DGRDAKAPVLGRFCG-SKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
DG+D +LG F G S + + +T ++++L F SD +GFQ
Sbjct: 1298 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ 1343
Score = 145 bits (365), Expect = 2e-34
Identities = 133/479 (27%), Positives = 201/479 (41%), Gaps = 64/479 (13%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 1064 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1119
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 1120 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1178
Query: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
++ C P R G + SC GY L RC
Sbjct: 1179 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1238
Query: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 1239 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1295
Query: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
+ G + L G F G S + ++S N + +EF SD + +GF+ + S +
Sbjct: 1296 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1353
Query: 708 SKDNGGCQ-----QDCVNTFGSYECQ-CRSGFVLHDNK----HDCKEAGCDHKVTS---- 753
+D G Q D + GS C G+ LH + + D+ + S
Sbjct: 1354 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1413
Query: 754 --------TSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
+SG I SP +P Y + C W I PG+ V L F+ D E+ ++D L
Sbjct: 1414 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA----SHDIL 1469
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKG----FQASHATEC 860
V+DG +L GS PE + +T + + ++F +D + + G F +S AT C
Sbjct: 1470 RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1528
Score = 115 bits (287), Expect = 3e-25
Identities = 88/291 (30%), Positives = 126/291 (43%), Gaps = 38/291 (13%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 179
Query: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
N G + L + + SC GY L + R E
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Query: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 295
Query: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 296 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 113 bits (282), Expect = 1e-24
Identities = 77/291 (26%), Positives = 129/291 (44%), Gaps = 38/291 (13%)
Query: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
CGG L LNG+I SPG+P YP NC W ++A + RI + F F E +YD++
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 120
Query: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710
+ G + + G P +TS + + SD VS GFK ++ + S
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 179
Query: 711 NGGCQQDCV------NTFGSYECQCRSGFVLHDNKH------------------DCK-EA 745
N G V + C +G++L + C+ E
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Query: 746 GCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
C + +SG I+SP++P++Y + +CTW I + PG + L F + +E + YD+L
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
E+ + P G P P+++ + + L F +D++ + +GF A +
Sbjct: 296 EI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 100 bits (250), Expect = 5e-21
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 2280 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2335
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 2336 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2393
Query: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
C P +CL +G+ +C G L D C+
Sbjct: 2394 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2453
Query: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 2454 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2509
Query: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 2510 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2566
Score = 97.8 bits (242), Expect = 4e-20
Identities = 76/299 (25%), Positives = 134/299 (44%), Gaps = 68/299 (22%)
Query: 737 DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRV-KLTFMEMDIE 795
D++ CK C + SGT TSPN+P +Y S +C W I++ ++V ++ F E D+
Sbjct: 538 DHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL- 596
Query: 796 SQPECAYDHLEVFDGRDAKAP--VLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
E YD L + DG + P VL GS P+ +++ S+M+L +D SV GF+
Sbjct: 597 ---EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFK 653
Query: 854 ASH----ATECG--GQVRADVKTKDLYSH-------AQFG------------DNN----- 883
++ CG G ++ D +S+ QFG +NN
Sbjct: 654 VNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 713
Query: 884 -----------------------YPGG----VDCEWVIVAEEGYGVELVFQTFEVEEETD 916
YP G ++C W I+++ G + L F F++E +
Sbjct: 714 IPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ-- 771
Query: 917 CGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
+D++ + DG +P LG + G+ P + S + ++F +D +++ +GF++ Y +
Sbjct: 772 --FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 828
Score = 67.8 bits (164), Expect = 5e-11
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Y ++C W I EG G+++ +F E +D ++ +DG D+ APRLG Y G+
Sbjct: 1959 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 2014
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
P + S +++ + F SD +++ GFHL YT+
Sbjct: 2015 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2046
Score = 66.6 bits (161), Expect = 1e-10
Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NYP +DC W I G+GV L F F T+ +DY+E+ G T+ +GR G
Sbjct: 2130 NYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSSETSTVIGRLSGPQ 2185
Query: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
P ++S + FHSD + K+GFH+ Y + + Q
Sbjct: 2186 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2222
Score = 65.9 bits (159), Expect = 2e-10
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG + A T +YS + YP DC W++ G G+ + F + E Y
Sbjct: 2283 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2334
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGF 969
D++ ++DG D +P++G++ G+ E VYS + +L+KFHSD T GF
Sbjct: 2335 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGF 2382
Score = 64.3 bits (155), Expect = 5e-10
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 2276 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2333
Query: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 2334 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2385
Score = 63.2 bits (152), Expect = 1e-09
Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
YP G +C WVI+AEE +++VFQ+F +EEE YDY+ L+DG+ R G
Sbjct: 85 YPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLSLYDGHPHPTNFRTRLTGFHL 140
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
P V S ++ SD ++ GF + Y
Sbjct: 141 PPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 170
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 491 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 538
Query: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 539 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 597
Query: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 598 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 654
Query: 430 VYEAI----CGGDVKKDYG 444
Y+ I CG YG
Sbjct: 655 NYKEIEKESCGDPGTPLYG 673
Score = 62.4 bits (150), Expect = 2e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 1588 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1643
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 1644 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1695
Score = 61.2 bits (147), Expect = 5e-09
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 1939 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1994
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 1995 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2047
Score = 60.8 bits (146), Expect = 6e-09
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 2111 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2166
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 2167 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2218
Score = 59.7 bits (143), Expect = 1e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 2467 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2522
Query: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 2523 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2580
Query: 560 EQRCLNTLGS-YKCSCDPGYEL 580
+ L S + +CD G+ L
Sbjct: 2581 ISQTGGQLNSVVRWACDRGFRL 2602
Score = 59.3 bits (142), Expect = 2e-08
Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 293
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
YLE+ SE T+ G P I S + L L FV+D + GF+ +
Sbjct: 294 YLEIEG--SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 349
Query: 552 SRPNRGGCEQRCLNTLGSYKCSCDP 576
+ G E+ T G+ + P
Sbjct: 350 HTTSTGELEEHNRTTTGAIAVASTP 374
Score = 58.5 bits (140), Expect = 3e-08
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 877 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 936
Query: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 937 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 992
Query: 424 GKGFFAVYEAI 434
GF YE++
Sbjct: 993 NNGFKIHYESV 1003
Score = 57.4 bits (137), Expect = 7e-08
Identities = 36/113 (31%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG TL+ G SP +P GY +C W I +I + F S L YDY+
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
+ DG R R G LP P+ ST S + S GF YE +
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEEL 173
Score = 57.0 bits (136), Expect = 9e-08
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 1234 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1291
Query: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 1292 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1348
Query: 434 ICGGDVKKDYGHIQSPNYP 452
+ H + P P
Sbjct: 1349 F-------ELSHCEDPGIP 1360
Score = 55.1 bits (131), Expect = 3e-07
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 1753 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1809
Query: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 1810 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1867
Query: 432 EAI 434
+A+
Sbjct: 1868 QAV 1870
Score = 54.7 bits (130), Expect = 4e-07
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 1405 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1464
Query: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 1465 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1518
Score = 50.1 bits (118), Expect = 1e-05
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 12/114 (10%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG +R + + S F N Y DC W IVAE G + L+F F++EE+ Y
Sbjct: 241 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 292
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
DY+E+ + + P G P + S + + + F +D +GF Y
Sbjct: 293 DYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 882 NNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS 941
++YP C W I E+GY + + + F+ E+E +D ++++DG + +P L G
Sbjct: 2476 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2531
Query: 942 -GPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+ S G V +++ +D KKGF +RY
Sbjct: 2532 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2564
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
NY +C + I + G G+ + +TF + + D ++++DG D T LG + G+
Sbjct: 1260 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1314
Query: 943 PPEEVYSAGDSVL-VKFHSDDTITKKGFHLRYTS 975
S+ + L ++F+SD T +GF L YTS
Sbjct: 1315 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1348
Score = 45.1 bits (105), Expect = 3e-04
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 1067 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1122
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 1123 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1160
Score = 38.9 bits (89), Expect = 0.024
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 2456 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2510
Query: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 2511 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2570
Query: 437 GDVKKDYGHIQS 448
+G+I S
Sbjct: 2571 TPESPPHGYIIS 2582
>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
sapiens]
Length = 380
Score = 172 bits (436), Expect = 1e-42
Identities = 96/279 (34%), Positives = 146/279 (52%), Gaps = 25/279 (8%)
Query: 595 LTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG 654
L + G I SPG+P YP + W + P +RI L F F E + +C+YD+V+V +
Sbjct: 24 LNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET- 82
Query: 655 LTADSKLHGKFCGSEKP--------EVITSQYNNMRVEFKSDNTVSKK--GFKAHFFS-D 703
+ ++ FCG E EV+ S + M + F+SD + ++ GF AH+ + D
Sbjct: 83 ---EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 704 KDECSK---DNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITS 760
DEC + + C C N G Y C CR G++LH + C+ D+ T +G ITS
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 761 PNWPDKYPSKKECTWAISSTPGHRVKLTFMEM-DIESQPE--CAYDHLEVFDGRDAKAPV 817
P++P+ YP EC + I G V L F ++ DIE PE C YD++++ G V
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PKV 255
Query: 818 LGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
LG FCG K PEP+ + + F+SDNS + +G++ S+
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 151 bits (381), Expect = 3e-36
Identities = 90/282 (31%), Positives = 139/282 (49%), Gaps = 25/282 (8%)
Query: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502
+G IQSP YPD Y W I V +GF + L F F +E C YDY++V
Sbjct: 28 FGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETE 83
Query: 503 STLIGRYCGYEKPDD--------IKSTSSRLWLKFVSDGSINK--AGFAVNFFK-EVDEC 551
++ +CG E D + S S + + F SD S + GF ++ +VDEC
Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDEC 143
Query: 552 S--RPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACG-GFLTKLNGSITSPGWP 608
C+ C N +G Y CSC GY L D R C C T+ G ITSP +P
Sbjct: 144 KEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP 203
Query: 609 KEYPPNKNCIWQLVAPTQYRISLQF-DFFETEGND--VCKYDFVEVRSGLTADSKLHGKF 665
YP + C++ + + ++LQF D F+ E + C YD+++++ G K+ G F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PKVLGPF 259
Query: 666 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
CG + PE I++Q +++ + F SDN+ +G++ + + +EC
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNEC 301
Score = 107 bits (268), Expect = 4e-23
Identities = 85/276 (30%), Positives = 123/276 (44%), Gaps = 68/276 (24%)
Query: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKA 815
G I SP +PD YPS E TW I+ G R+KL FM ++ES C YD+++V + +
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETED 84
Query: 816 PVLGRFCGSKKP--------EPVLATGSRMFLRFYSDNSVQRK--GFQASHAT----ECG 861
VL FCG + E VL+ GS M + F SD S + + GF A + EC
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 862 GQVRADVKTKDLYSHAQFGD---------------------------------------- 881
+ ++ D Y H G
Sbjct: 145 EREDEELSC-DHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP 203
Query: 882 NNYPGGVDCEWVIVAEEGYGVELVFQT-FEVEE--ETDCGYDYMELFDGYDSTAPR-LGR 937
N YP +C + I EEG+ V L F+ F++E+ E C YDY+++ G P+ LG
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG-----PKVLGP 258
Query: 938 YCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+CG PE + + SVL+ FHSD++ +G+ L Y
Sbjct: 259 FCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 95.9 bits (237), Expect = 2e-19
Identities = 90/333 (27%), Positives = 137/333 (41%), Gaps = 73/333 (21%)
Query: 316 LYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLC 375
L K A L + G SP YP+ Y + W I+V G +I L F +L S LC
Sbjct: 14 LSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLC 73
Query: 376 WYDYVEVRDGFWRKAPLRGRFCGSKL--------PEPIVSTDSRLWVEFRS--SSNWVGK 425
YDYV+V + + FCG + E ++S S + + FRS S+
Sbjct: 74 EYDYVKVE----TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFT 129
Query: 426 GFFAVYEAICGGDVKK--------DY---------------------------------- 443
GF A Y A+ + K+ D+
Sbjct: 130 GFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNL 189
Query: 444 -----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQS-FEIERHDS--CAYDYLEV 495
G I SP++P+ Y S C++ I++ EGF V L F+ F+IE H C YDY+++
Sbjct: 190 FTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI 249
Query: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR-- 553
+ G ++G +CG + P+ I + S + + F SD S G+ +++ +EC
Sbjct: 250 KVG----PKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQ 305
Query: 554 -PNRGGCE--QRCLNTLGSYKCSCDPGYELAPD 583
P G E Q SCD GY++ D
Sbjct: 306 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKD 338
>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
precursor [Homo sapiens]
Length = 728
Score = 172 bits (436), Expect = 1e-42
Identities = 96/279 (34%), Positives = 146/279 (52%), Gaps = 25/279 (8%)
Query: 595 LTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG 654
L + G I SPG+P YP + W + P +RI L F F E + +C+YD+V+V +
Sbjct: 24 LNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET- 82
Query: 655 LTADSKLHGKFCGSEKP--------EVITSQYNNMRVEFKSDNTVSKK--GFKAHFFS-D 703
+ ++ FCG E EV+ S + M + F+SD + ++ GF AH+ + D
Sbjct: 83 ---EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 704 KDECSK---DNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITS 760
DEC + + C C N G Y C CR G++LH + C+ D+ T +G ITS
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 761 PNWPDKYPSKKECTWAISSTPGHRVKLTFMEM-DIESQPE--CAYDHLEVFDGRDAKAPV 817
P++P+ YP EC + I G V L F ++ DIE PE C YD++++ G V
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PKV 255
Query: 818 LGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
LG FCG K PEP+ + + F+SDNS + +G++ S+
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 151 bits (381), Expect = 3e-36
Identities = 90/282 (31%), Positives = 139/282 (49%), Gaps = 25/282 (8%)
Query: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502
+G IQSP YPD Y W I V +GF + L F F +E C YDY++V
Sbjct: 28 FGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETE 83
Query: 503 STLIGRYCGYEKPDD--------IKSTSSRLWLKFVSDGSINK--AGFAVNFFK-EVDEC 551
++ +CG E D + S S + + F SD S + GF ++ +VDEC
Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDEC 143
Query: 552 S--RPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACG-GFLTKLNGSITSPGWP 608
C+ C N +G Y CSC GY L D R C C T+ G ITSP +P
Sbjct: 144 KEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP 203
Query: 609 KEYPPNKNCIWQLVAPTQYRISLQF-DFFETEGND--VCKYDFVEVRSGLTADSKLHGKF 665
YP + C++ + + ++LQF D F+ E + C YD+++++ G K+ G F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PKVLGPF 259
Query: 666 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
CG + PE I++Q +++ + F SDN+ +G++ + + +EC
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNEC 301
Score = 107 bits (268), Expect = 4e-23
Identities = 85/276 (30%), Positives = 123/276 (44%), Gaps = 68/276 (24%)
Query: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKA 815
G I SP +PD YPS E TW I+ G R+KL FM ++ES C YD+++V + +
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETED 84
Query: 816 PVLGRFCGSKKP--------EPVLATGSRMFLRFYSDNSVQRK--GFQASHAT----ECG 861
VL FCG + E VL+ GS M + F SD S + + GF A + EC
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 862 GQVRADVKTKDLYSHAQFGD---------------------------------------- 881
+ ++ D Y H G
Sbjct: 145 EREDEELSC-DHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP 203
Query: 882 NNYPGGVDCEWVIVAEEGYGVELVFQT-FEVEE--ETDCGYDYMELFDGYDSTAPR-LGR 937
N YP +C + I EEG+ V L F+ F++E+ E C YDY+++ G P+ LG
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG-----PKVLGP 258
Query: 938 YCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+CG PE + + SVL+ FHSD++ +G+ L Y
Sbjct: 259 FCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 95.9 bits (237), Expect = 2e-19
Identities = 90/333 (27%), Positives = 137/333 (41%), Gaps = 73/333 (21%)
Query: 316 LYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLC 375
L K A L + G SP YP+ Y + W I+V G +I L F +L S LC
Sbjct: 14 LSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLC 73
Query: 376 WYDYVEVRDGFWRKAPLRGRFCGSKL--------PEPIVSTDSRLWVEFRS--SSNWVGK 425
YDYV+V + + FCG + E ++S S + + FRS S+
Sbjct: 74 EYDYVKVE----TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFT 129
Query: 426 GFFAVYEAICGGDVKK--------DY---------------------------------- 443
GF A Y A+ + K+ D+
Sbjct: 130 GFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNL 189
Query: 444 -----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQS-FEIERHDS--CAYDYLEV 495
G I SP++P+ Y S C++ I++ EGF V L F+ F+IE H C YDY+++
Sbjct: 190 FTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI 249
Query: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR-- 553
+ G ++G +CG + P+ I + S + + F SD S G+ +++ +EC
Sbjct: 250 KVG----PKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQ 305
Query: 554 -PNRGGCE--QRCLNTLGSYKCSCDPGYELAPD 583
P G E Q SCD GY++ D
Sbjct: 306 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKD 338
>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
precursor [Homo sapiens]
Length = 699
Score = 172 bits (436), Expect = 1e-42
Identities = 96/279 (34%), Positives = 146/279 (52%), Gaps = 25/279 (8%)
Query: 595 LTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG 654
L + G I SPG+P YP + W + P +RI L F F E + +C+YD+V+V +
Sbjct: 24 LNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET- 82
Query: 655 LTADSKLHGKFCGSEKP--------EVITSQYNNMRVEFKSDNTVSKK--GFKAHFFS-D 703
+ ++ FCG E EV+ S + M + F+SD + ++ GF AH+ + D
Sbjct: 83 ---EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 704 KDECSK---DNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITS 760
DEC + + C C N G Y C CR G++LH + C+ D+ T +G ITS
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 761 PNWPDKYPSKKECTWAISSTPGHRVKLTFMEM-DIESQPE--CAYDHLEVFDGRDAKAPV 817
P++P+ YP EC + I G V L F ++ DIE PE C YD++++ G V
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PKV 255
Query: 818 LGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
LG FCG K PEP+ + + F+SDNS + +G++ S+
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 151 bits (381), Expect = 3e-36
Identities = 90/282 (31%), Positives = 139/282 (49%), Gaps = 25/282 (8%)
Query: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502
+G IQSP YPD Y W I V +GF + L F F +E C YDY++V
Sbjct: 28 FGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETE 83
Query: 503 STLIGRYCGYEKPDD--------IKSTSSRLWLKFVSDGSINK--AGFAVNFFK-EVDEC 551
++ +CG E D + S S + + F SD S + GF ++ +VDEC
Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDEC 143
Query: 552 S--RPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACG-GFLTKLNGSITSPGWP 608
C+ C N +G Y CSC GY L D R C C T+ G ITSP +P
Sbjct: 144 KEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP 203
Query: 609 KEYPPNKNCIWQLVAPTQYRISLQF-DFFETEGND--VCKYDFVEVRSGLTADSKLHGKF 665
YP + C++ + + ++LQF D F+ E + C YD+++++ G K+ G F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PKVLGPF 259
Query: 666 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
CG + PE I++Q +++ + F SDN+ +G++ + + +EC
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNEC 301
Score = 107 bits (268), Expect = 4e-23
Identities = 85/276 (30%), Positives = 123/276 (44%), Gaps = 68/276 (24%)
Query: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKA 815
G I SP +PD YPS E TW I+ G R+KL FM ++ES C YD+++V + +
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETED 84
Query: 816 PVLGRFCGSKKP--------EPVLATGSRMFLRFYSDNSVQRK--GFQASHAT----ECG 861
VL FCG + E VL+ GS M + F SD S + + GF A + EC
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 862 GQVRADVKTKDLYSHAQFGD---------------------------------------- 881
+ ++ D Y H G
Sbjct: 145 EREDEELSC-DHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP 203
Query: 882 NNYPGGVDCEWVIVAEEGYGVELVFQT-FEVEE--ETDCGYDYMELFDGYDSTAPR-LGR 937
N YP +C + I EEG+ V L F+ F++E+ E C YDY+++ G P+ LG
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG-----PKVLGP 258
Query: 938 YCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
+CG PE + + SVL+ FHSD++ +G+ L Y
Sbjct: 259 FCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 95.9 bits (237), Expect = 2e-19
Identities = 90/333 (27%), Positives = 137/333 (41%), Gaps = 73/333 (21%)
Query: 316 LYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLC 375
L K A L + G SP YP+ Y + W I+V G +I L F +L S LC
Sbjct: 14 LSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLC 73
Query: 376 WYDYVEVRDGFWRKAPLRGRFCGSKL--------PEPIVSTDSRLWVEFRS--SSNWVGK 425
YDYV+V + + FCG + E ++S S + + FRS S+
Sbjct: 74 EYDYVKVE----TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFT 129
Query: 426 GFFAVYEAICGGDVKK--------DY---------------------------------- 443
GF A Y A+ + K+ D+
Sbjct: 130 GFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNL 189
Query: 444 -----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQS-FEIERHDS--CAYDYLEV 495
G I SP++P+ Y S C++ I++ EGF V L F+ F+IE H C YDY+++
Sbjct: 190 FTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI 249
Query: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR-- 553
+ G ++G +CG + P+ I + S + + F SD S G+ +++ +EC
Sbjct: 250 KVG----PKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQ 305
Query: 554 -PNRGGCE--QRCLNTLGSYKCSCDPGYELAPD 583
P G E Q SCD GY++ D
Sbjct: 306 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKD 338
>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
Length = 449
Score = 164 bits (415), Expect = 4e-40
Identities = 92/269 (34%), Positives = 141/269 (52%), Gaps = 36/269 (13%)
Query: 434 ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 493
+CGGDVK + G++ S +P+ Y P+K CIW I V EG V L+F+ F++E H +C YD L
Sbjct: 36 LCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDAL 95
Query: 494 EVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 553
EV G S +GR+CG +P + + +++ L+ +D GF + + S
Sbjct: 96 EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY-------SG 148
Query: 554 PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK-EYP 612
G E + CGG L K G++T+P WP+ +YP
Sbjct: 149 RATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYP 181
Query: 613 PNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG-LTADSKLHGKFCGSEKP 671
P +C W ++AP I+L F+ F+ E + C+YD V V +G ++ DS+ GKFCG P
Sbjct: 182 PGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVP 241
Query: 672 EVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
I+S+ N + V+F SD +V+ GF A +
Sbjct: 242 GSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 160 bits (404), Expect = 7e-39
Identities = 84/237 (35%), Positives = 128/237 (54%), Gaps = 13/237 (5%)
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
C V SG + S +P+ YP KEC W I+ G V L+F D+E P C YD LE
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF------QASHATE- 859
VF G LGRFCG+ +P P++A G+++ LR +D +GF +A+ TE
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 860 --CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 917
CGG++ K + + + +++YP G+ C W I+A + L F+ F++E +T C
Sbjct: 157 QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 918 GYDYMELFDG-YDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
YD + +F+G + RLG++CG P + S G+ +LV+F SD ++T GF Y
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 145 bits (366), Expect = 2e-34
Identities = 83/279 (29%), Positives = 129/279 (46%), Gaps = 36/279 (12%)
Query: 582 PDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN 641
P+ R CGG + +G + S G+P YPPNK CIW + P +SL F F+ E +
Sbjct: 28 PNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELH 87
Query: 642 DVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
C+YD +EV +G + G+FCG+ +P + + N + + +D +GF +
Sbjct: 88 PACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY- 146
Query: 702 SDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSP 761
SG +H C ++ GT+T+P
Sbjct: 147 -----------------------------SGRATSGTEHQF----CGGRLEKAQGTLTTP 173
Query: 762 NWPDK-YPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAK-APVLG 819
NWP+ YP C+W I + P + LTF + D+E C YD + VF+G + + LG
Sbjct: 174 NWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLG 233
Query: 820 RFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
+FCG P + + G+ + ++F SD SV GF AS+ T
Sbjct: 234 KFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKT 272
Score = 134 bits (338), Expect = 3e-31
Identities = 74/234 (31%), Positives = 118/234 (50%), Gaps = 11/234 (4%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG ++ +G +S +PN Y + C+W I+V G+ + L+F DL C YD +E
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 433
V G GRFCG+ P P+V+ +++ + + G+GF Y
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 434 -ICGGDVKKDYGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
CGG ++K G + +PN+P+ DY P C W I + LTF+ F++E C YD
Sbjct: 157 QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYD 216
Query: 492 YLEVRDGH-SESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
+ V +G S+ S +G++CG P I S + L ++FVSD S+ GF+ ++
Sbjct: 217 SVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 77.8 bits (190), Expect = 5e-14
Identities = 42/124 (33%), Positives = 64/124 (51%), Gaps = 4/124 (3%)
Query: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
CGG DVK + Y ++ N YP +C W I EG V L F+ F++E C Y
Sbjct: 37 CGG----DVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRY 92
Query: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
D +E+F G ++ RLGR+CG+ P + + G+ V ++ +D+ +GF L Y+
Sbjct: 93 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATS 152
Query: 980 DTLH 983
T H
Sbjct: 153 GTEH 156
Score = 67.4 bits (163), Expect = 6e-11
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Query: 322 CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
CG L+ + G ++P +P Y + C W I P + I L F DL C YD V
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSV 218
Query: 381 EVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 439
V +G R G+FCG +P I S + L V+F S + GF A Y+ + G
Sbjct: 219 SVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTA 278
Query: 440 KKDYG 444
K+ G
Sbjct: 279 KEGQG 283
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 155 bits (392), Expect = 2e-37
Identities = 96/297 (32%), Positives = 142/297 (47%), Gaps = 21/297 (7%)
Query: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
++ CGG + G SPNYPD Y P+ C+W IQV+ + L ++ IE SC +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
LE+ E + R CG P + + +S L + FVSD S+ GF + +
Sbjct: 201 RLEL---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWY-----QA 252
Query: 552 SRPNRGGC---EQRC---LNTLGSYKCSCDPGYELAPDKRRCEA---ACGGFLTKLNGSI 602
P RG C E RC + L C D+ C A CGG LT L G+
Sbjct: 253 MAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTF 312
Query: 603 TSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV-RSGLTADSKL 661
++P + ++YP C W + P + I LQF F E D CK+D+VEV + + L
Sbjct: 313 STPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSL 372
Query: 662 HGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA---HFFSDKDECSKDNGGCQ 715
G+FCG+E P + S ++ + V F++D+ +S GF A F + ++ C CQ
Sbjct: 373 LGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENPCGPSELSCQ 429
Score = 139 bits (349), Expect = 2e-32
Identities = 81/286 (28%), Positives = 144/286 (50%), Gaps = 16/286 (5%)
Query: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
++ CGG L+ G +SP +P YPPN +C+W + T + I L+ + E C +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS---DK 704
+E+ + CG P + + +++ V F SD++V GF A + + +
Sbjct: 201 RLELSPEPEGPLL---RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGR 257
Query: 705 DECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDC--KEAGCDHKVTSTSGTITSPN 762
C+ D C Q + C + ++ +C K +GC +T GT ++P+
Sbjct: 258 GSCAHDEFRCDQ-LICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPS 316
Query: 763 WPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKA-PVLGRF 821
+ +YP + CTW IS GH ++L F +E+Q EC +D++EV++ + A +LGRF
Sbjct: 317 YLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRF 376
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH----ATE--CG 861
CG++ P ++++ + + F +D+ + GF A++ ATE CG
Sbjct: 377 CGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENPCG 422
Score = 117 bits (293), Expect = 5e-26
Identities = 83/290 (28%), Positives = 124/290 (42%), Gaps = 55/290 (18%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L G FSSP YP+ Y + HCVW I V I L +L + C +D +E
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTD-SRLWVEFRSSSNWVGKGFFAVYEAI------ 434
+ + PL R CG ++P P ++T+ S L V F S S+ G GF A Y+A+
Sbjct: 204 LSPE--PEGPLL-RVCG-RVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGS 259
Query: 435 -----------------------------------------CGGDVKKDYGHIQSPNYPD 453
CGG++ G +P+Y
Sbjct: 260 CAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSYLQ 319
Query: 454 DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESS-TLIGRYCGY 512
Y +C W I V G + L F +F +E D C +DY+EV + S + +L+GR+CG
Sbjct: 320 QYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGA 379
Query: 513 EKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVDECSRPNRGGCE 560
E P + S+ L + F +D I+ GF+ + F + P+ C+
Sbjct: 380 EPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENPCGPSELSCQ 429
Score = 109 bits (273), Expect = 1e-23
Identities = 74/278 (26%), Positives = 115/278 (41%), Gaps = 55/278 (19%)
Query: 744 EAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYD 803
++ C ++ G +SPN+PD YP C W I H ++L + IES C +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 804 HLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA--------- 854
LE+ + + P+L R CG P + S + + F SD+SV+ GF A
Sbjct: 201 RLEL--SPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGR 257
Query: 855 --------------------------------------SHATECGGQVRADVKTKDLYSH 876
+ + CGG + T S+
Sbjct: 258 GSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSY 317
Query: 877 AQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTA-PRL 935
Q YP + C W I G+ +EL F F +E + +C +DY+E+++ S A L
Sbjct: 318 LQ----QYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLL 373
Query: 936 GRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
GR+CG+ PP + S+ + V F +D I+ GF Y
Sbjct: 374 GRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 72.0 bits (175), Expect = 3e-12
Identities = 45/117 (38%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 318 KCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY 377
K CG L G FS+P Y Y + C W ISV G I L F + L C +
Sbjct: 297 KFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKF 356
Query: 378 DYVEVRDGFWRKA-PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
DYVEV + A L GRFCG++ P +VS+ L V FR+ GF A Y A
Sbjct: 357 DYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLA 413
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 7/126 (5%)
Query: 848 QRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQ 907
Q G S + CGG + + +S + D YP C W I + ++L +
Sbjct: 132 QESGVSPSPQSTCGGLLSGP---RGFFSSPNYPDP-YPPNTHCVWHIQVATDHAIQLKIE 187
Query: 908 TFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKK 967
+E C +D +EL + P L R CG PP + + +LV F SD ++
Sbjct: 188 ALSIESVASCLFDRLEL--SPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGF 244
Query: 968 GFHLRY 973
GFH Y
Sbjct: 245 GFHAWY 250
>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
Length = 415
Score = 152 bits (385), Expect = 1e-36
Identities = 82/268 (30%), Positives = 134/268 (50%), Gaps = 37/268 (13%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG + + G I S +P Y P+ C W+I V EG V L F+ ++E + C YD+++
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
V +GH+ IGR+CG +P + S+ +++ ++ +SD + GF F + P
Sbjct: 93 VYNGHANGQR-IGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF-----SAAEP 146
Query: 555 NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWP-KEYPP 613
N G + CGG L + +GS +P WP ++YP
Sbjct: 147 NERG-----------------------------DQYCGGLLDRPSGSFKTPNWPDRDYPA 177
Query: 614 NKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV-RSGLTADSKLHGKFCGSEKPE 672
C+W +VAP I L+F+ F+ E ++ C+YD+V V G D++ GK+CG P
Sbjct: 178 GVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDSPPA 237
Query: 673 VITSQYNNMRVEFKSDNTVSKKGFKAHF 700
I S+ N + ++F SD +++ GF H+
Sbjct: 238 PIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 149 bits (375), Expect = 2e-35
Identities = 80/233 (34%), Positives = 127/233 (54%), Gaps = 14/233 (6%)
Query: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
C +T SG I S +P YP +CTW I+ G V L F +D+ES C YD ++
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATE------- 859
V++G A +GRFCG+ +P ++++G++M ++ SD + GF A +
Sbjct: 93 VYNGH-ANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 860 --CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 917
CGG + + + + D +YP GV C W IVA + +EL F+ F+VE + C
Sbjct: 152 QYCGGLLD---RPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYC 208
Query: 918 GYDYMELFDGYD-STAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGF 969
YDY+ +F+G + + A R+G+YCG PP + S + +L++F SD ++T GF
Sbjct: 209 RYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGF 261
Score = 148 bits (373), Expect = 3e-35
Identities = 89/284 (31%), Positives = 137/284 (48%), Gaps = 31/284 (10%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L +G S +P Y + C W+I+V G+ ++LNF +DL LC YD+V+
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 433
V +G + GRFCG+ P +VS+ +++ V+ S +N G GF A++ A
Sbjct: 93 VYNGHANGQRI-GRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 434 -ICGGDVKKDYGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
CGG + + G ++PN+PD DY C+W I + + L F+ F++ER + C YD
Sbjct: 152 QYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYD 211
Query: 492 YLEV-RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKE--- 547
Y+ V G + IG+YCG P I S + L ++F+SD S+ GF ++
Sbjct: 212 YVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKK 271
Query: 548 --------------VDECSRPNRGGCEQRC--LNTLGSYKCSCD 575
V +P C+Q+C TL CS D
Sbjct: 272 LPTTTEQPVTTTFPVTTGLKPTVALCQQKCRRTGTLEGNYCSSD 315
Score = 61.6 bits (148), Expect = 3e-09
Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Query: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
YP C W I EG V L F+ ++E + C YD++++++G+ + R+GR+CG+
Sbjct: 53 YPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGH-ANGQRIGRFCGTFR 111
Query: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTK 977
P + S+G+ ++V+ SD GF +++ +
Sbjct: 112 PGALVSSGNKMMVQMISDANTAGNGFMAMFSAAE 145
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 150 bits (379), Expect = 6e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
GS CS + T NG+I SPG+P+
Sbjct: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 145 bits (367), Expect = 1e-34
Identities = 91/275 (33%), Positives = 139/275 (50%), Gaps = 47/275 (17%)
Query: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
F+E+R G + + L GK CG+ P I S + + ++F SD GF + E
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY-----EI 141
Query: 708 SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKY 767
K +DC F TS +GTI SP +P+KY
Sbjct: 142 FKTGS---EDCSKNF-----------------------------TSPNGTIESPGFPEKY 169
Query: 768 PSKKECTWAISSTPGHRVKLTFMEMDIESQP------ECAYDHLEVFDGRDAKAPVLGRF 821
P +CT+ I + P + L F+ D+E P +C YD L+++DG P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
CG+K P + ++ + L F++D +V + GF A +
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 138 bits (347), Expect = 3e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 545 F 545
+
Sbjct: 265 Y 265
Score = 129 bits (325), Expect = 1e-29
Identities = 69/232 (29%), Positives = 119/232 (51%), Gaps = 17/232 (7%)
Query: 755 SGTITSPNWPDKYPSKKECTWAI-SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
+G ITSP +P YPS + C W + + P ++ L F + +C YD +E+ DG
Sbjct: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSE 96
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH------ATECGGQVRAD 867
A +LG+ CG+ P ++++GS ++++F SD + Q GF + + +C +
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 868 VKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE------ETDCGYDY 921
T + + YP +DC + I+A+ + L F F++E E DC YD+
Sbjct: 157 NGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDW 212
Query: 922 MELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
++++DG P +G+YCG+ P E+ S+ + + FH+D + K GF RY
Sbjct: 213 LDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 150 bits (379), Expect = 6e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
GS CS + T NG+I SPG+P+
Sbjct: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 145 bits (367), Expect = 1e-34
Identities = 91/275 (33%), Positives = 139/275 (50%), Gaps = 47/275 (17%)
Query: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
F+E+R G + + L GK CG+ P I S + + ++F SD GF + E
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY-----EI 141
Query: 708 SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKY 767
K +DC F TS +GTI SP +P+KY
Sbjct: 142 FKTGS---EDCSKNF-----------------------------TSPNGTIESPGFPEKY 169
Query: 768 PSKKECTWAISSTPGHRVKLTFMEMDIESQP------ECAYDHLEVFDGRDAKAPVLGRF 821
P +CT+ I + P + L F+ D+E P +C YD L+++DG P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
CG+K P + ++ + L F++D +V + GF A +
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 138 bits (347), Expect = 3e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 545 F 545
+
Sbjct: 265 Y 265
Score = 129 bits (325), Expect = 1e-29
Identities = 69/232 (29%), Positives = 119/232 (51%), Gaps = 17/232 (7%)
Query: 755 SGTITSPNWPDKYPSKKECTWAI-SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
+G ITSP +P YPS + C W + + P ++ L F + +C YD +E+ DG
Sbjct: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSE 96
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH------ATECGGQVRAD 867
A +LG+ CG+ P ++++GS ++++F SD + Q GF + + +C +
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 868 VKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE------ETDCGYDY 921
T + + YP +DC + I+A+ + L F F++E E DC YD+
Sbjct: 157 NGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDW 212
Query: 922 MELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
++++DG P +G+YCG+ P E+ S+ + + FH+D + K GF RY
Sbjct: 213 LDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 150 bits (379), Expect = 6e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
GS CS + T NG+I SPG+P+
Sbjct: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 145 bits (367), Expect = 1e-34
Identities = 91/275 (33%), Positives = 139/275 (50%), Gaps = 47/275 (17%)
Query: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
F+E+R G + + L GK CG+ P I S + + ++F SD GF + E
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY-----EI 141
Query: 708 SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKY 767
K +DC F TS +GTI SP +P+KY
Sbjct: 142 FKTGS---EDCSKNF-----------------------------TSPNGTIESPGFPEKY 169
Query: 768 PSKKECTWAISSTPGHRVKLTFMEMDIESQP------ECAYDHLEVFDGRDAKAPVLGRF 821
P +CT+ I + P + L F+ D+E P +C YD L+++DG P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
CG+K P + ++ + L F++D +V + GF A +
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 138 bits (347), Expect = 3e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 545 F 545
+
Sbjct: 265 Y 265
Score = 129 bits (325), Expect = 1e-29
Identities = 69/232 (29%), Positives = 119/232 (51%), Gaps = 17/232 (7%)
Query: 755 SGTITSPNWPDKYPSKKECTWAI-SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
+G ITSP +P YPS + C W + + P ++ L F + +C YD +E+ DG
Sbjct: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSE 96
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH------ATECGGQVRAD 867
A +LG+ CG+ P ++++GS ++++F SD + Q GF + + +C +
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 868 VKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE------ETDCGYDY 921
T + + YP +DC + I+A+ + L F F++E E DC YD+
Sbjct: 157 NGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDW 212
Query: 922 MELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
++++DG P +G+YCG+ P E+ S+ + + FH+D + K GF RY
Sbjct: 213 LDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 150 bits (379), Expect = 6e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
GS CS + T NG+I SPG+P+
Sbjct: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 145 bits (367), Expect = 1e-34
Identities = 91/275 (33%), Positives = 139/275 (50%), Gaps = 47/275 (17%)
Query: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
F+E+R G + + L GK CG+ P I S + + ++F SD GF + E
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY-----EI 141
Query: 708 SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKY 767
K +DC F TS +GTI SP +P+KY
Sbjct: 142 FKTGS---EDCSKNF-----------------------------TSPNGTIESPGFPEKY 169
Query: 768 PSKKECTWAISSTPGHRVKLTFMEMDIESQP------ECAYDHLEVFDGRDAKAPVLGRF 821
P +CT+ I + P + L F+ D+E P +C YD L+++DG P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
CG+K P + ++ + L F++D +V + GF A +
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 138 bits (347), Expect = 3e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 545 F 545
+
Sbjct: 265 Y 265
Score = 129 bits (325), Expect = 1e-29
Identities = 69/232 (29%), Positives = 119/232 (51%), Gaps = 17/232 (7%)
Query: 755 SGTITSPNWPDKYPSKKECTWAI-SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
+G ITSP +P YPS + C W + + P ++ L F + +C YD +E+ DG
Sbjct: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSE 96
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH------ATECGGQVRAD 867
A +LG+ CG+ P ++++GS ++++F SD + Q GF + + +C +
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 868 VKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE------ETDCGYDY 921
T + + YP +DC + I+A+ + L F F++E E DC YD+
Sbjct: 157 NGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDW 212
Query: 922 MELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
++++DG P +G+YCG+ P E+ S+ + + FH+D + K GF RY
Sbjct: 213 LDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 150 bits (379), Expect = 6e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
GS CS + T NG+I SPG+P+
Sbjct: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 145 bits (367), Expect = 1e-34
Identities = 91/275 (33%), Positives = 139/275 (50%), Gaps = 47/275 (17%)
Query: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
F+E+R G + + L GK CG+ P I S + + ++F SD GF + E
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY-----EI 141
Query: 708 SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKY 767
K +DC F TS +GTI SP +P+KY
Sbjct: 142 FKTGS---EDCSKNF-----------------------------TSPNGTIESPGFPEKY 169
Query: 768 PSKKECTWAISSTPGHRVKLTFMEMDIESQP------ECAYDHLEVFDGRDAKAPVLGRF 821
P +CT+ I + P + L F+ D+E P +C YD L+++DG P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
CG+K P + ++ + L F++D +V + GF A +
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 138 bits (347), Expect = 3e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 545 F 545
+
Sbjct: 265 Y 265
Score = 129 bits (325), Expect = 1e-29
Identities = 69/232 (29%), Positives = 119/232 (51%), Gaps = 17/232 (7%)
Query: 755 SGTITSPNWPDKYPSKKECTWAI-SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
+G ITSP +P YPS + C W + + P ++ L F + +C YD +E+ DG
Sbjct: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSE 96
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH------ATECGGQVRAD 867
A +LG+ CG+ P ++++GS ++++F SD + Q GF + + +C +
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 868 VKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE------ETDCGYDY 921
T + + YP +DC + I+A+ + L F F++E E DC YD+
Sbjct: 157 NGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDW 212
Query: 922 MELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
++++DG P +G+YCG+ P E+ S+ + + FH+D + K GF RY
Sbjct: 213 LDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 150 bits (379), Expect = 6e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
GS CS + T NG+I SPG+P+
Sbjct: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 145 bits (367), Expect = 1e-34
Identities = 91/275 (33%), Positives = 139/275 (50%), Gaps = 47/275 (17%)
Query: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
F+E+R G + + L GK CG+ P I S + + ++F SD GF + E
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY-----EI 141
Query: 708 SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKY 767
K +DC F TS +GTI SP +P+KY
Sbjct: 142 FKTGS---EDCSKNF-----------------------------TSPNGTIESPGFPEKY 169
Query: 768 PSKKECTWAISSTPGHRVKLTFMEMDIESQP------ECAYDHLEVFDGRDAKAPVLGRF 821
P +CT+ I + P + L F+ D+E P +C YD L+++DG P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
CG+K P + ++ + L F++D +V + GF A +
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 138 bits (347), Expect = 3e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 545 F 545
+
Sbjct: 265 Y 265
Score = 129 bits (325), Expect = 1e-29
Identities = 69/232 (29%), Positives = 119/232 (51%), Gaps = 17/232 (7%)
Query: 755 SGTITSPNWPDKYPSKKECTWAI-SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
+G ITSP +P YPS + C W + + P ++ L F + +C YD +E+ DG
Sbjct: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSE 96
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH------ATECGGQVRAD 867
A +LG+ CG+ P ++++GS ++++F SD + Q GF + + +C +
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 868 VKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE------ETDCGYDY 921
T + + YP +DC + I+A+ + L F F++E E DC YD+
Sbjct: 157 NGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDW 212
Query: 922 MELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
++++DG P +G+YCG+ P E+ S+ + + FH+D + K GF RY
Sbjct: 213 LDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 148 bits (373), Expect = 3e-35
Identities = 94/293 (32%), Positives = 140/293 (47%), Gaps = 33/293 (11%)
Query: 591 CGGFLTKLN--------GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642
CG T L G + SPG+P EY ++ W L AP YR+ L F F+ E +
Sbjct: 11 CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
Query: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEKPEV--------ITSQYNNMRVEFKSDNTVSKK 694
+C+YDFV++ SG +K+ CG E + S +++ + F+SD + K
Sbjct: 71 LCEYDFVKLSSG----AKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP 126
Query: 695 --GFKAHFFS-DKDECSKDNGG---CQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCD 748
GF+A + + D DEC G C C N G + C CR+G+VLH NK C
Sbjct: 127 FTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSG 186
Query: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFME-MDIESQPE--CAYDHL 805
T SG ++SP +P YP CT++IS G V L F+E D+E+ PE C YD L
Sbjct: 187 QVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFL 246
Query: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
++ R+ P FCG P + + + + F +D S G++ + +
Sbjct: 247 KIQTDREEHGP----FCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTS 295
Score = 135 bits (341), Expect = 1e-31
Identities = 86/282 (30%), Positives = 135/282 (47%), Gaps = 25/282 (8%)
Query: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502
+G + SP +P +Y + W + G+ + L F F++E C YD++++ G
Sbjct: 27 FGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
Query: 503 STLIGRYCGYEKPDDIK--------STSSRLWLKFVSDGSINK--AGFAVNFFKE-VDEC 551
+TL CG E D + S S L + F SD S K GF + E +DEC
Sbjct: 87 ATL----CGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
Query: 552 S-RPNRG-GCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGG-FLTKLNGSITSPGWP 608
P C+ C N LG + CSC GY L +KR C A C G T+ +G ++SP +P
Sbjct: 143 QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYP 202
Query: 609 KEYPPNKNCIWQLVAPTQYRISLQF-DFF--ETEGNDVCKYDFVEVRSGLTADSKLHGKF 665
+ YP +C + + + + L F + F ET +C YDF+++++ D + HG F
Sbjct: 203 RPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQT----DREEHGPF 258
Query: 666 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
CG P I ++ N + + F +D + G+K H+ S C
Sbjct: 259 CGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPC 300
Score = 92.4 bits (228), Expect = 2e-18
Identities = 99/398 (24%), Positives = 152/398 (38%), Gaps = 91/398 (22%)
Query: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
G +SP +P Y+ W ++ PG ++ L FT DL S LC YD+V++ G A
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
Query: 391 PLRGRFCGSKLPEP--------IVSTDSRLWVEFRS--SSNWVGKGFFAVY--------- 431
+ CG + + S S L + FRS S+ GF A Y
Sbjct: 84 KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
Query: 432 -------------------------------------EAICGGDV-KKDYGHIQSPNYPD 453
A+C G V + G + SP YP
Sbjct: 144 VAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPR 203
Query: 454 DYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDS--CAYDYLEVRDGHSESSTLIGRYC 510
Y C + I + EGF V L F +SF++E H C YD+L+++ E G +C
Sbjct: 204 PYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEH----GPFC 259
Query: 511 GYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP-----NRGGCEQRCLN 565
G P I++ S+ + + FV+D S + G+ +++ C P Q
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYI 319
Query: 566 TLGSYKCSCDPGYELAPDK---RRCEAAC---GGFLTKLNG-SITSPGWPKEYPPNKNCI 618
S+ C+ GYEL + A C G + + SI G P + P + +
Sbjct: 320 LKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGR--V 377
Query: 619 WQLVAP--TQYRISLQFDFFET-------EGNDVCKYD 647
+ P T Y+ +Q+ ET +G VC+ D
Sbjct: 378 EYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEAD 415
Score = 83.6 bits (205), Expect = 9e-16
Identities = 69/277 (24%), Positives = 116/277 (41%), Gaps = 64/277 (23%)
Query: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKA 815
G + SP +P +Y + +E W +++ PG+R++L F D+E C YD +++ G A
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
Query: 816 PVLGRFCGSKKPEPVLATGSRMF--------LRFYSDNSVQRK--GFQASHATECGGQVR 865
VL CG + + A G F + F SD S ++ GF+A +A E + +
Sbjct: 84 KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
Query: 866 A---DVKTKDLYSHAQFGD----------------------------------------N 882
+ T D + H G
Sbjct: 144 VAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPR 203
Query: 883 NYPGGVDCEWVIVAEEGYGVELVF-QTFEVEE--ETDCGYDYMELFDGYDSTAPRLGRYC 939
YP C + I EEG+ V L F ++F+VE ET C YD++++ + P +C
Sbjct: 204 PYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGP----FC 259
Query: 940 GSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTST 976
G P + + ++V + F +D++ G+ + YTST
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTST 296
Score = 51.6 bits (122), Expect = 4e-06
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 323 GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFT---SLDLYRSRLCWYDY 379
G+ +G SSPEYP Y C + IS+ G +IL+F ++ + LC YD+
Sbjct: 186 GQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDF 245
Query: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEF 416
++++ P FCG LP I + + + + F
Sbjct: 246 LKIQTDREEHGP----FCGKTLPHRIETKSNTVTITF 278
>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
Length = 705
Score = 142 bits (359), Expect = 1e-33
Identities = 94/291 (32%), Positives = 143/291 (49%), Gaps = 37/291 (12%)
Query: 597 KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLT 656
KL G +TSP +PK YP N + PT YR+ L F F+ E ++ C YD+V++ +
Sbjct: 24 KLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----S 79
Query: 657 ADSKLHGKFCGS---------EKPEVITSQYNNMRVEFKSDNTVSK-------KGFKAHF 700
AD K G+FCG K E + SQ N M + F +D + + KGF A++
Sbjct: 80 ADKKSLGRFCGQLGSPLGNPPGKKEFM-SQGNKMLLTFHTDFSNEENGTIMFYKGFLAYY 138
Query: 701 FS-DKDEC-SKDNGG-------CQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKV 751
+ D DEC S+ G CQ C N G Y C CR G+ L +++H C+
Sbjct: 139 QAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELY 198
Query: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFME---MDIESQPECAYDHLEVF 808
T SG I+S +P YP C ++I G + L F+E +D Q C YD L+++
Sbjct: 199 TEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIY 258
Query: 809 DGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATE 859
A +G FCG ++P + + + + L F++D S +G++ + TE
Sbjct: 259 ----ANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Score = 125 bits (315), Expect = 1e-28
Identities = 84/303 (27%), Positives = 149/303 (49%), Gaps = 40/303 (13%)
Query: 436 GGDV---KKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
GG + +K +G + SP +P Y + I V G+ V L FQ F++E + C YDY
Sbjct: 16 GGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDY 75
Query: 493 LEVRDGHSESSTLIGRYCGY--------EKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
+++ S +GR+CG + S +++ L F +D S N+ + F
Sbjct: 76 VKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFS-NEENGTIMF 130
Query: 545 FK---------EVDECSRPNRGG-------CEQRCLNTLGSYKCSCDPGYELAPDKRRCE 588
+K ++DEC+ ++ G C+ C N +G Y CSC PGYEL D+ C+
Sbjct: 131 YKGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQ 190
Query: 589 AACGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF-DFFETEGNDV--C 644
A C L T+ +G I+S +P+ YPP+ C + + + L+F + F+ + + C
Sbjct: 191 AECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHC 250
Query: 645 KYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDK 704
YD +++ A+ K G+FCG ++P + + N + + F +D + +G+K + ++
Sbjct: 251 PYDQLQI----YANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEI 306
Query: 705 DEC 707
+C
Sbjct: 307 IKC 309
Score = 85.9 bits (211), Expect = 2e-16
Identities = 68/300 (22%), Positives = 125/300 (41%), Gaps = 74/300 (24%)
Query: 742 CKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECA 801
C+ G G +TSP +P YP+ E T I+ G+RVKL F + D+E C
Sbjct: 13 CRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCF 72
Query: 802 YDHLEVFDGRDAKAPVLGRFCGS--------KKPEPVLATGSRMFLRFYSDNSVQRKG-- 851
YD++++ A LGRFCG + ++ G++M L F++D S + G
Sbjct: 73 YDYVKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTI 128
Query: 852 ---------FQASHATECGGQVRADVK--------------------------------- 869
+QA EC + + +
Sbjct: 129 MFYKGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHS 188
Query: 870 -----TKDLYSHAQ------FGDNNYPGGVDCEWVIVAEEGYGVELVF-QTFEVE--EET 915
+ +LY+ A +YP + C + I E G + L F + F+++ ++
Sbjct: 189 CQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQV 248
Query: 916 DCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
C YD ++++ + +G +CG P ++ ++ ++V + F +D++ +G+ LRYT+
Sbjct: 249 HCPYDQLQIY----ANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 76.6 bits (187), Expect = 1e-13
Identities = 74/294 (25%), Positives = 121/294 (41%), Gaps = 78/294 (26%)
Query: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
G +SP +P Y + I+V G ++ L F DL S C+YDYV++ K
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISAD---KK 83
Query: 391 PLRGRFCG---SKLPEP-----IVSTDSRLWVEFRSSSN-------WVGKGFFAVYEAI- 434
L GRFCG S L P +S +++ + F + + KGF A Y+A+
Sbjct: 84 SL-GRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVD 142
Query: 435 ---------------------------------C--GGDVKKDY---------------- 443
C G ++++D
Sbjct: 143 LDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYTEAS 202
Query: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDS--CAYDYLEVRDGHS 500
G+I S YP Y P C + I+V G + L F + F+I+ H C YD L++
Sbjct: 203 GYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGK 262
Query: 501 ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
IG +CG ++P D+ ++S+ + L F +D S + G+ + + E+ +C +P
Sbjct: 263 N----IGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQP 312
Score = 38.5 bits (88), Expect = 0.031
Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 309 DIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFT--- 365
++ + R + E +++G SS EYP Y + C + I V G + L F
Sbjct: 181 ELQEDRHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPF 240
Query: 366 SLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGK 425
+D ++ C YD +++ + G FCG + P + ++ + + + F + + +
Sbjct: 241 DIDDHQQVHCPYDQLQI----YANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSR 296
Query: 426 GF 427
G+
Sbjct: 297 GW 298
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 139 bits (350), Expect = 1e-32
Identities = 83/236 (35%), Positives = 121/236 (51%), Gaps = 13/236 (5%)
Query: 322 CGETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVT-PGEKIILNFTSLDLYRSRLCWYDY 379
CG+T++ +S G +SP YP+ Y C W I P ++I++NF R C YDY
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDY 86
Query: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----- 434
VEV DG RG+FCG P P+VS+ L+++F S G GF YE
Sbjct: 87 VEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPE 146
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDS------C 488
C + G I+SP +P+ Y S C + + + + L F+SF++E + C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 489 AYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
YD LE+ DG + IGRYCG + P I+S+S L + F +D +I K GF+ N+
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 132 bits (332), Expect = 2e-30
Identities = 82/268 (30%), Positives = 126/268 (47%), Gaps = 51/268 (19%)
Query: 600 GSITSPGWPKEYPPNKNCIWQLVAPTQY-RISLQFD-FFETEGNDVCKYDFVEVRSGLTA 657
G +TSPG+P Y P++ C W + AP Y RI + F+ F+ E D CKYD+VEV G
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENE 95
Query: 658 DSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF--FSDKDECSKDNGGCQ 715
+ GKFCG P + S + ++F SD GF + F ECS++
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN----- 150
Query: 716 QDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTW 775
T+ SG I SP +P+KYP+ ECT+
Sbjct: 151 -----------------------------------YTTPSGVIKSPGFPEKYPNSLECTY 175
Query: 776 AISSTPGHRVKLTFMEMDIE--SQPE----CAYDHLEVFDGRDAKAPVLGRFCGSKKPEP 829
+ + + L F D+E S P C YD LE++DG P +GR+CG K P
Sbjct: 176 IVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGR 235
Query: 830 VLATGSRMFLRFYSDNSVQRKGFQASHA 857
+ ++ + + FY+D+++ ++GF A+++
Sbjct: 236 IRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 130 bits (327), Expect = 6e-30
Identities = 67/228 (29%), Positives = 119/228 (52%), Gaps = 10/228 (4%)
Query: 756 GTITSPNWPDKYPSKKECTWAISST-PGHRVKLTFM-EMDIESQPECAYDHLEVFDGRDA 813
G +TSP +P Y ++C W I + P R+ + F D+E + +C YD++EVFDG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKYDYVEVFDGENE 95
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT-ECGGQVRADVKTKD 872
G+FCG P PV+++G +F++F SD GF + + G + + T
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 873 LYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETD------CGYDYMELFD 926
+ YP ++C +++ A + + L F++F++E +++ C YD +E++D
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 927 GYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYT 974
G+ P +GRYCG P + S+ + + F++D I K+GF Y+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 130 bits (326), Expect = 8e-30
Identities = 84/287 (29%), Positives = 136/287 (47%), Gaps = 52/287 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFH-VGLTFQS-FEIERHDSCAYD 491
CG +K + G++ SP YP Y PS+ C W IQ + + + + F F++E D C YD
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYD 85
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Y+EV DG +E+ G++CG P + S+ L++KFVSD + AGF++ + FK
Sbjct: 86 YVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGP 145
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
ECS+ T +G I SPG+P+
Sbjct: 146 ECSQN----------------------------------------YTTPSGVIKSPGFPE 165
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP + C + + AP I L+F+ F+ E G C+YD +E+ G G
Sbjct: 166 KYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIG 225
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710
++CG + P I S + + F +D+ ++K+GF A++ + S+D
Sbjct: 226 RYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED 272
Score = 62.4 bits (150), Expect = 2e-09
Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 7/130 (5%)
Query: 320 PACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR------ 373
P C + +G SP +P Y + C + + +IIL F S DL
Sbjct: 145 PECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGM 204
Query: 374 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
C YD +E+ DGF P GR+CG K P I S+ L + F + S +GF A Y +
Sbjct: 205 FCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY-S 263
Query: 434 ICGGDVKKDY 443
+ V +D+
Sbjct: 264 VLQSSVSEDF 273
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 139 bits (350), Expect = 1e-32
Identities = 83/236 (35%), Positives = 121/236 (51%), Gaps = 13/236 (5%)
Query: 322 CGETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVT-PGEKIILNFTSLDLYRSRLCWYDY 379
CG+T++ +S G +SP YP+ Y C W I P ++I++NF R C YDY
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDY 86
Query: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----- 434
VEV DG RG+FCG P P+VS+ L+++F S G GF YE
Sbjct: 87 VEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPE 146
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDS------C 488
C + G I+SP +P+ Y S C + + + + L F+SF++E + C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 489 AYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
YD LE+ DG + IGRYCG + P I+S+S L + F +D +I K GF+ N+
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 132 bits (332), Expect = 2e-30
Identities = 82/268 (30%), Positives = 126/268 (47%), Gaps = 51/268 (19%)
Query: 600 GSITSPGWPKEYPPNKNCIWQLVAPTQY-RISLQFD-FFETEGNDVCKYDFVEVRSGLTA 657
G +TSPG+P Y P++ C W + AP Y RI + F+ F+ E D CKYD+VEV G
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENE 95
Query: 658 DSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF--FSDKDECSKDNGGCQ 715
+ GKFCG P + S + ++F SD GF + F ECS++
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN----- 150
Query: 716 QDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTW 775
T+ SG I SP +P+KYP+ ECT+
Sbjct: 151 -----------------------------------YTTPSGVIKSPGFPEKYPNSLECTY 175
Query: 776 AISSTPGHRVKLTFMEMDIE--SQPE----CAYDHLEVFDGRDAKAPVLGRFCGSKKPEP 829
+ + + L F D+E S P C YD LE++DG P +GR+CG K P
Sbjct: 176 IVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGR 235
Query: 830 VLATGSRMFLRFYSDNSVQRKGFQASHA 857
+ ++ + + FY+D+++ ++GF A+++
Sbjct: 236 IRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 130 bits (327), Expect = 6e-30
Identities = 67/228 (29%), Positives = 119/228 (52%), Gaps = 10/228 (4%)
Query: 756 GTITSPNWPDKYPSKKECTWAISST-PGHRVKLTFM-EMDIESQPECAYDHLEVFDGRDA 813
G +TSP +P Y ++C W I + P R+ + F D+E + +C YD++EVFDG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKYDYVEVFDGENE 95
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT-ECGGQVRADVKTKD 872
G+FCG P PV+++G +F++F SD GF + + G + + T
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 873 LYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETD------CGYDYMELFD 926
+ YP ++C +++ A + + L F++F++E +++ C YD +E++D
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 927 GYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYT 974
G+ P +GRYCG P + S+ + + F++D I K+GF Y+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 130 bits (326), Expect = 8e-30
Identities = 84/287 (29%), Positives = 136/287 (47%), Gaps = 52/287 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFH-VGLTFQS-FEIERHDSCAYD 491
CG +K + G++ SP YP Y PS+ C W IQ + + + + F F++E D C YD
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYD 85
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Y+EV DG +E+ G++CG P + S+ L++KFVSD + AGF++ + FK
Sbjct: 86 YVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGP 145
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
ECS+ T +G I SPG+P+
Sbjct: 146 ECSQN----------------------------------------YTTPSGVIKSPGFPE 165
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP + C + + AP I L+F+ F+ E G C+YD +E+ G G
Sbjct: 166 KYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIG 225
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710
++CG + P I S + + F +D+ ++K+GF A++ + S+D
Sbjct: 226 RYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED 272
Score = 62.4 bits (150), Expect = 2e-09
Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 7/130 (5%)
Query: 320 PACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR------ 373
P C + +G SP +P Y + C + + +IIL F S DL
Sbjct: 145 PECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGM 204
Query: 374 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
C YD +E+ DGF P GR+CG K P I S+ L + F + S +GF A Y +
Sbjct: 205 FCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY-S 263
Query: 434 ICGGDVKKDY 443
+ V +D+
Sbjct: 264 VLQSSVSEDF 273
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 139 bits (350), Expect = 1e-32
Identities = 83/236 (35%), Positives = 121/236 (51%), Gaps = 13/236 (5%)
Query: 322 CGETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVT-PGEKIILNFTSLDLYRSRLCWYDY 379
CG+T++ +S G +SP YP+ Y C W I P ++I++NF R C YDY
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDY 86
Query: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----- 434
VEV DG RG+FCG P P+VS+ L+++F S G GF YE
Sbjct: 87 VEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPE 146
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDS------C 488
C + G I+SP +P+ Y S C + + + + L F+SF++E + C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 489 AYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
YD LE+ DG + IGRYCG + P I+S+S L + F +D +I K GF+ N+
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 132 bits (332), Expect = 2e-30
Identities = 82/268 (30%), Positives = 126/268 (47%), Gaps = 51/268 (19%)
Query: 600 GSITSPGWPKEYPPNKNCIWQLVAPTQY-RISLQFD-FFETEGNDVCKYDFVEVRSGLTA 657
G +TSPG+P Y P++ C W + AP Y RI + F+ F+ E D CKYD+VEV G
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENE 95
Query: 658 DSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF--FSDKDECSKDNGGCQ 715
+ GKFCG P + S + ++F SD GF + F ECS++
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN----- 150
Query: 716 QDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTW 775
T+ SG I SP +P+KYP+ ECT+
Sbjct: 151 -----------------------------------YTTPSGVIKSPGFPEKYPNSLECTY 175
Query: 776 AISSTPGHRVKLTFMEMDIE--SQPE----CAYDHLEVFDGRDAKAPVLGRFCGSKKPEP 829
+ + + L F D+E S P C YD LE++DG P +GR+CG K P
Sbjct: 176 IVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGR 235
Query: 830 VLATGSRMFLRFYSDNSVQRKGFQASHA 857
+ ++ + + FY+D+++ ++GF A+++
Sbjct: 236 IRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 130 bits (327), Expect = 6e-30
Identities = 67/228 (29%), Positives = 119/228 (52%), Gaps = 10/228 (4%)
Query: 756 GTITSPNWPDKYPSKKECTWAISST-PGHRVKLTFM-EMDIESQPECAYDHLEVFDGRDA 813
G +TSP +P Y ++C W I + P R+ + F D+E + +C YD++EVFDG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKYDYVEVFDGENE 95
Query: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT-ECGGQVRADVKTKD 872
G+FCG P PV+++G +F++F SD GF + + G + + T
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 873 LYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETD------CGYDYMELFD 926
+ YP ++C +++ A + + L F++F++E +++ C YD +E++D
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 927 GYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYT 974
G+ P +GRYCG P + S+ + + F++D I K+GF Y+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 130 bits (326), Expect = 8e-30
Identities = 84/287 (29%), Positives = 136/287 (47%), Gaps = 52/287 (18%)
Query: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFH-VGLTFQS-FEIERHDSCAYD 491
CG +K + G++ SP YP Y PS+ C W IQ + + + + F F++E D C YD
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYD 85
Query: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Y+EV DG +E+ G++CG P + S+ L++KFVSD + AGF++ + FK
Sbjct: 86 YVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGP 145
Query: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
ECS+ T +G I SPG+P+
Sbjct: 146 ECSQN----------------------------------------YTTPSGVIKSPGFPE 165
Query: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
+YP + C + + AP I L+F+ F+ E G C+YD +E+ G G
Sbjct: 166 KYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIG 225
Query: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710
++CG + P I S + + F +D+ ++K+GF A++ + S+D
Sbjct: 226 RYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED 272
Score = 62.4 bits (150), Expect = 2e-09
Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 7/130 (5%)
Query: 320 PACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR------ 373
P C + +G SP +P Y + C + + +IIL F S DL
Sbjct: 145 PECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGM 204
Query: 374 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
C YD +E+ DGF P GR+CG K P I S+ L + F + S +GF A Y +
Sbjct: 205 FCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY-S 263
Query: 434 ICGGDVKKDY 443
+ V +D+
Sbjct: 264 VLQSSVSEDF 273
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 138 bits (348), Expect = 2e-32
Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%)
Query: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
CG L ++G FSSP YP Y + CVW I V G +I L F++L L C +DYVE
Sbjct: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
Query: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441
+ DG + L G+ C + S+ +R+ + FRS ++ GF A Y +
Sbjct: 1075 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1131
Query: 442 DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500
++ N Y +C R+++ G G S+ I+ + R +
Sbjct: 1132 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184
Query: 501 ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558
+ G G DD++ T S LW N+ F+ N C+ G
Sbjct: 1185 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1231
Query: 559 --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616
C L+T P L + + +CGGFL++ +G +SP +P YP N
Sbjct: 1232 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 1282
Query: 617 CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676
C+W + YR+++ F + EG C YD++EV G S L + C + TS
Sbjct: 1283 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 1339
Query: 677 QYNNMRVEFKSDNTVSKKGFKAHFFS 702
N M + F SD++++++GF+A ++S
Sbjct: 1340 SSNFMSIRFISDHSITRRGFRAEYYS 1365
Score = 104 bits (260), Expect = 4e-22
Identities = 87/356 (24%), Positives = 144/356 (40%), Gaps = 87/356 (24%)
Query: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
R + CGGFL +G+ +SP +P YP N C+W++ + YRI+L F + E + C
Sbjct: 1010 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1069
Query: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKD 705
+D+VE+ G S L GK C + ++ TS YN M + F+SD + GF A + S
Sbjct: 1070 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPS 1128
Query: 706 ECS------KDNGGCQQDCVNTF--GSYECQCRSGFVLHDNKHDCKEAGCDHKVT----- 752
+ + + G V + G++ C + + + + C++ GC V+
Sbjct: 1129 DATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA 1188
Query: 753 ---STSGTIT----------------------SPNWPDKYPSKKECTWAISSTPGHRVKL 787
S SG IT S N + + C+ STP + +
Sbjct: 1189 YFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNI 1248
Query: 788 TFMEMDIE-----SQP-----------------ECAYD---------------------- 803
T D SQP +C +D
Sbjct: 1249 TRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGC 1308
Query: 804 ---HLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
++EVFDG +P++ R C + ++ + M +RF SD+S+ R+GF+A +
Sbjct: 1309 NYDYIEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1363
Score = 77.8 bits (190), Expect = 5e-14
Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%)
Query: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
CGG + + G SP YP +Y + C+W I+V + V + F+ ++E C YDY+E
Sbjct: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1314
Query: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
V DG SS LI R C + S+S+ + ++F+SD SI + GF ++ S P
Sbjct: 1315 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 1367
Query: 555 NRGGCEQRCL 564
+ CL
Sbjct: 1368 SNDSTNLLCL 1377
Score = 77.4 bits (189), Expect = 6e-14
Identities = 52/199 (26%), Positives = 89/199 (44%), Gaps = 15/199 (7%)
Query: 745 AGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDH 804
+ C + SGT +SP++P YP+ +C W I G+R+ L F + +E+ C++D+
Sbjct: 1013 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
Query: 805 LEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQV 864
+E+FDG + +LG+ C + + ++ +RM + F SD S Q GF A + +
Sbjct: 1073 VEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1131
Query: 865 RADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMEL 924
V Y Y GG W V ++ + ++ + V + CG L
Sbjct: 1132 LRLVNLNSSYGLCAGRVEIYHGGT---WGTVCDDSWTIQ---EAEVVCRQLGCGRAVSAL 1185
Query: 925 FDGYDSTAPRLGRYCGSGP 943
+ Y + GSGP
Sbjct: 1186 GNAYFGS--------GSGP 1196
Score = 68.9 bits (167), Expect = 2e-11
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 3/103 (2%)
Query: 879 FGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRY 938
F NYP C W I + Y V ++F+ +V+ E C YDY+E+FDG ++P + R
Sbjct: 1272 FYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSSPLIARV 1329
Query: 939 CGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDT 981
C G S+ + + ++F SD +IT++GF Y S+ D+
Sbjct: 1330 C-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDS 1371
Score = 65.5 bits (158), Expect = 2e-10
Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Query: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
+CG L +G+FSSP YP Y + CVW I V ++ + F + L C YDY+
Sbjct: 1256 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1313
Query: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
EV DG +R +PL R C S+ + + + F S + +GF A Y
Sbjct: 1314 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1363
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,550,141
Number of Sequences: 37866
Number of extensions: 2152125
Number of successful extensions: 9288
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 185
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 5744
Number of HSP's gapped (non-prelim): 2384
length of query: 986
length of database: 18,247,518
effective HSP length: 112
effective length of query: 874
effective length of database: 14,006,526
effective search space: 12241703724
effective search space used: 12241703724
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.