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Search of human proteins with 5453567
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453567 craniofacial development protein 1 [Homo sapiens]
(299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453567 craniofacial development protein 1 [Homo sapiens] 585 e-167
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 59 5e-09
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 58 1e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 58 1e-08
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 57 2e-08
gi|55956788 nucleolin [Homo sapiens] 56 3e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 55 1e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 53 3e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 52 5e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 50 2e-06
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 50 2e-06
gi|5453904 RAD51 associated protein 1 isoform b [Homo sapiens] 50 3e-06
gi|195947391 RAD51 associated protein 1 isoform a [Homo sapiens] 50 3e-06
gi|126362983 ribosomal RNA processing 15 homolog [Homo sapiens] 50 3e-06
gi|157738619 smoothelin-like 1 [Homo sapiens] 50 3e-06
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 49 5e-06
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 48 9e-06
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 48 1e-05
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 48 1e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 48 1e-05
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 48 1e-05
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 48 1e-05
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] 47 2e-05
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] 47 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 2e-05
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 47 2e-05
gi|157694505 LINE-1 type transposase domain containing 1 [Homo s... 47 2e-05
gi|9966799 UTP3, small subunit processome component [Homo sapiens] 47 3e-05
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 47 3e-05
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] 47 3e-05
>gi|5453567 craniofacial development protein 1 [Homo sapiens]
Length = 299
Score = 585 bits (1507), Expect = e-167
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 60
MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA
Sbjct: 1 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 60
Query: 61 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 120
RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND
Sbjct: 61 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 120
Query: 121 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK 180
VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK
Sbjct: 121 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK 180
Query: 181 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMST 240
EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMST
Sbjct: 181 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMST 240
Query: 241 LEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP 299
LEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP
Sbjct: 241 LEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP 299
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 58.9 bits (141), Expect = 5e-09
Identities = 74/316 (23%), Positives = 130/316 (41%), Gaps = 49/316 (15%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQT---QKTQGKKRKAQSI 58
EE ED EE+E+ P G E+ V +V+E + +E+T G+ +
Sbjct: 181 EENKKED-KEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPK 239
Query: 59 PARKRRQGG------LSLEEEEEEDANSESEGSSSEE-EDDAAEQEKGIGSEDARKKKED 111
+R QG +EEE++E A +E +EE E AEQ+K I E AR + E+
Sbjct: 240 QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEE 299
Query: 112 ELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDF 171
+ A + + + + EE + + + +K EE +E +++K +
Sbjct: 300 KAAAQ------ERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEE--KR 351
Query: 172 AGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGM------- 224
A EE + KE + + E + + E+EK + L + + +
Sbjct: 352 AAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411
Query: 225 ------------------SSLLGKIGAKKQKMSTLEKSKL--DWESFKEEEGIGEELAIH 264
+++L K G +K ++ KL D +FK+EE E++
Sbjct: 412 KIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI--- 468
Query: 265 NRGKEGYIERKAFLDR 280
+ KE E K+F+DR
Sbjct: 469 KKDKEPKEEVKSFMDR 484
Score = 53.1 bits (126), Expect = 3e-07
Identities = 59/262 (22%), Positives = 115/262 (43%), Gaps = 22/262 (8%)
Query: 24 EYSEDDVN---ELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANS 80
E D+++ ++ +ED+ E + + + ++R+ K+ + E EE+ A
Sbjct: 245 EQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ 304
Query: 81 ESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETE 140
E E +EE + E+EK E R K+E++ A + + K + + EE +
Sbjct: 305 ERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 364
Query: 141 ETSSSKLLVKAEELEKPK--ETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEK 198
+ + +AEE EK K E ++ K + A +E ++ E E K NEK
Sbjct: 365 RAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWV---NEK 421
Query: 199 EKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMS----TLEKSKLDWESFKEE 254
+ + + +A+ LK+ K+ AK++K+ T +K ++ E K++
Sbjct: 422 KAQEDKLQTAV--------LKKQGEEKGT--KVQAKREKLQEDKPTFKKEEIKDEKIKKD 471
Query: 255 EGIGEELAIHNRGKEGYIERKA 276
+ EE+ K+G+ E K+
Sbjct: 472 KEPKEEVKSFMDRKKGFTEVKS 493
Score = 35.0 bits (79), Expect = 0.080
Identities = 42/197 (21%), Positives = 79/197 (40%), Gaps = 15/197 (7%)
Query: 19 VPSGGEYSEDDVNELVKEDEVDGEEQT----QKTQGKKRKAQSIPARKRRQGGLSLEEEE 74
+PS ++ NE +++E Q ++T+ + Q R + +E+E
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 191
Query: 75 EEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPK---SKVPPST 131
EE+ GS E + + +EK +E + L ++ PK + S
Sbjct: 192 EEEEEKPKRGSIGENQVEVMVEEK--TTESQEETVVMSLKNGQISSEEPKQEEEREQGSD 249
Query: 132 QVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATS----- 186
++ E+ EE + + LE +E E++K + A E R+ E A +
Sbjct: 250 EISHHEKMEEEDKERAEAERARLE-AEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 187 KEAKSFFKQNEKEKPQA 203
+EA+ + E+EK A
Sbjct: 309 REAEERERMREEEKRAA 325
Score = 35.0 bits (79), Expect = 0.080
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 34/182 (18%)
Query: 41 GEEQTQKTQGKKRKAQSIPA------RKRRQGGLSLEEEEEEDANSESEGSSSEEED--- 91
GE ++++ + K+K Q +KR + LEEEE+ E++ EEE+
Sbjct: 544 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 603
Query: 92 --DAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLV 149
+ E+ + +E +K ED L K P KG SS K+
Sbjct: 604 LKEEIERRRAEAAEKRQKMPEDGL---------SDDKKPFKCFTPKG------SSLKIEE 648
Query: 150 KAEELEKP-KETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSA 208
+AE L K +++ VK T + + ++D+ ++ S + + KP S
Sbjct: 649 RAEFLNKSVQKSSGVKST-------HQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASD 701
Query: 209 LP 210
LP
Sbjct: 702 LP 703
Score = 32.7 bits (73), Expect = 0.40
Identities = 34/152 (22%), Positives = 62/152 (40%), Gaps = 22/152 (14%)
Query: 70 LEEEEEEDANSESEG-----SSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVG-- 122
L ++ E+ E+E + +EE+ A E+ + E R+K+E+E + V
Sbjct: 10 LRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVN 69
Query: 123 -----PKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVR 177
P + +T + E +E + + L + EE + + E ++ K FD +
Sbjct: 70 AQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDAS 129
Query: 178 V----------TKEVDATSKEAKSFFKQNEKE 199
+ T E + T KE KS +Q E
Sbjct: 130 LSLPSRRMQNDTAENETTEKEEKSESRQERYE 161
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 57.8 bits (138), Expect = 1e-08
Identities = 53/249 (21%), Positives = 105/249 (42%), Gaps = 12/249 (4%)
Query: 27 EDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSS 86
+++ E +E E + E + ++ KK ++ + + G EEE +E+ E EG+
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544
Query: 87 SEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSK 146
S++ ++ +++G ++ +++E E A + + K E++EE ++ +
Sbjct: 545 SDQAEEGGSEKEGSSEKEEGEQEEGETEAE-----AEGEEAEAKEEKKVEEKSEEVATKE 599
Query: 147 LLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVP 206
LV ++EKP++ + + G+ V+ K EK K
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK------ 653
Query: 207 SALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNR 266
S +P P K S + K + K S +E++K E K E+ EE +
Sbjct: 654 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPK-SPVEEAKSKAEVGKGEQKEEEEKEVKEA 712
Query: 267 GKEGYIERK 275
KE +E+K
Sbjct: 713 PKEEKVEKK 721
Score = 43.5 bits (101), Expect = 2e-04
Identities = 49/184 (26%), Positives = 79/184 (42%), Gaps = 24/184 (13%)
Query: 24 EYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGL-----SLEEEEEEDA 78
E E +V E KE++V+ +E+ K +K+KA+S P ++ + S++ E++
Sbjct: 703 EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES-PVKEEAVAEVVTITKSVKVHLEKET 761
Query: 79 NSESEGSSSEEEDDAAEQEKGIGSEDARK-----KKEDELWASFLNDVGPKSKVPPSTQV 133
E + E+E + A E G E + K +KED + +V K +V T+
Sbjct: 762 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKED---IAVNGEVEGKEEVEQETKE 818
Query: 134 KKGEETEE----TSSSKLLVKAEELEKPKETEKVKITKVFDFA------GEEVRVTKEVD 183
K EE T+ L E+ K EKV +TK + G +TK V
Sbjct: 819 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVT 878
Query: 184 ATSK 187
T K
Sbjct: 879 VTQK 882
Score = 42.4 bits (98), Expect = 5e-04
Identities = 61/268 (22%), Positives = 107/268 (39%), Gaps = 27/268 (10%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
EE ++E+ + + + E E++ KE+E EE+ ++ +G K
Sbjct: 497 EEPEAEEEEVAAKKSPVKATAPEVKEEEGE---KEEEEGQEEEEEEDEGAKSDQAEEGGS 553
Query: 62 KRRQGGLSLEEE---EEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFL 118
++ G S +EE EE + +E+EG +E +++ +EK SE+ K+E A
Sbjct: 554 EKE--GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK---SEEVATKEELVADAKVE 608
Query: 119 NDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRV 178
KS VP S +KG+ S + K+ + P E + G+
Sbjct: 609 KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK-----------GKSPVP 657
Query: 179 TKEVDATSKEAKSFFKQNEKEK---PQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKK 235
V+ K S EK K P++ V A G G ++ + K K+
Sbjct: 658 KSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV--KEAPKE 715
Query: 236 QKMSTLEKSKLDWESFKEEEGIGEELAI 263
+K+ E+ D K+ E +E A+
Sbjct: 716 EKVEKKEEKPKDVPEKKKAESPVKEEAV 743
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 57.8 bits (138), Expect = 1e-08
Identities = 53/249 (21%), Positives = 105/249 (42%), Gaps = 12/249 (4%)
Query: 27 EDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSS 86
+++ E +E E + E + ++ KK ++ + + G EEE +E+ E EG+
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 168
Query: 87 SEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSK 146
S++ ++ +++G ++ +++E E A + + K E++EE ++ +
Sbjct: 169 SDQAEEGGSEKEGSSEKEEGEQEEGETEAE-----AEGEEAEAKEEKKVEEKSEEVATKE 223
Query: 147 LLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVP 206
LV ++EKP++ + + G+ V+ K EK K
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK------ 277
Query: 207 SALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNR 266
S +P P K S + K + K S +E++K E K E+ EE +
Sbjct: 278 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPK-SPVEEAKSKAEVGKGEQKEEEEKEVKEA 336
Query: 267 GKEGYIERK 275
KE +E+K
Sbjct: 337 PKEEKVEKK 345
Score = 43.5 bits (101), Expect = 2e-04
Identities = 49/184 (26%), Positives = 79/184 (42%), Gaps = 24/184 (13%)
Query: 24 EYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGL-----SLEEEEEEDA 78
E E +V E KE++V+ +E+ K +K+KA+S P ++ + S++ E++
Sbjct: 327 EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES-PVKEEAVAEVVTITKSVKVHLEKET 385
Query: 79 NSESEGSSSEEEDDAAEQEKGIGSEDARK-----KKEDELWASFLNDVGPKSKVPPSTQV 133
E + E+E + A E G E + K +KED + +V K +V T+
Sbjct: 386 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKED---IAVNGEVEGKEEVEQETKE 442
Query: 134 KKGEETEE----TSSSKLLVKAEELEKPKETEKVKITKVFDFA------GEEVRVTKEVD 183
K EE T+ L E+ K EKV +TK + G +TK V
Sbjct: 443 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVT 502
Query: 184 ATSK 187
T K
Sbjct: 503 VTQK 506
Score = 42.4 bits (98), Expect = 5e-04
Identities = 61/268 (22%), Positives = 107/268 (39%), Gaps = 27/268 (10%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
EE ++E+ + + + E E++ KE+E EE+ ++ +G K
Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEGE---KEEEEGQEEEEEEDEGAKSDQAEEGGS 177
Query: 62 KRRQGGLSLEEE---EEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFL 118
++ G S +EE EE + +E+EG +E +++ +EK SE+ K+E A
Sbjct: 178 EKE--GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK---SEEVATKEELVADAKVE 232
Query: 119 NDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRV 178
KS VP S +KG+ S + K+ + P E + G+
Sbjct: 233 KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK-----------GKSPVP 281
Query: 179 TKEVDATSKEAKSFFKQNEKEK---PQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKK 235
V+ K S EK K P++ V A G G ++ + K K+
Sbjct: 282 KSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV--KEAPKE 339
Query: 236 QKMSTLEKSKLDWESFKEEEGIGEELAI 263
+K+ E+ D K+ E +E A+
Sbjct: 340 EKVEKKEEKPKDVPEKKKAESPVKEEAV 367
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 57.4 bits (137), Expect = 2e-08
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 15/194 (7%)
Query: 13 EEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEE 72
E ED GGE E E+ E+E E++ + + K ++ K +G EE
Sbjct: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNE---EKGEAGKEDKDEKG----EE 155
Query: 73 EEEEDANSESEGSSSEEEDDAAEQEKGIGS-EDARKKKEDELWASFLNDVGPKSKVPPST 131
+ +ED N +G ++E++D + E G G+ ED ++K EDE + + +
Sbjct: 156 DGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDE------KEEEDRKETGDGK 209
Query: 132 QVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKS 191
+ + G+E + K VK +E EK +E K + AG+E KE + +E +
Sbjct: 210 ENEDGKEKGDKKEGK-DVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEI 268
Query: 192 FFKQNEKEKPQANV 205
+KE+PQ+ V
Sbjct: 269 KEDDGKKEEPQSIV 282
Score = 46.2 bits (108), Expect = 3e-05
Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 14/162 (8%)
Query: 3 EFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARK 62
E +E+ E++ED GE ++D +E +ED + + +K + K K K
Sbjct: 122 EVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDG----K 177
Query: 63 RRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVG 122
+ + G E+ +E E E +E D E E G D ++ K DV
Sbjct: 178 KGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK----------DVK 227
Query: 123 PKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVK 164
K K+ E E + K +E E+ KE +++K
Sbjct: 228 VKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 56.2 bits (134), Expect = 3e-08
Identities = 52/199 (26%), Positives = 85/199 (42%), Gaps = 32/199 (16%)
Query: 3 EFDSEDFSTSEEDEDYVP-------SGGEYSEDDVNELVKEDEVDG--------EEQTQK 47
E D ED +EDED + + SED+ +E ++DE D EE +
Sbjct: 154 EEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMET 213
Query: 48 TQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSE---- 103
T K +KA + K + +EEE+++ + + E++DD ++E+ E
Sbjct: 214 TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273
Query: 104 -DARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEK 162
+A K++ E+ K K P + +K E TE T++ L V K K
Sbjct: 274 KEAPGKRKKEM---------AKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELK 324
Query: 163 VKITKVF---DFAGEEVRV 178
I+ VF D A +VR+
Sbjct: 325 TGISDVFAKNDLAVVDVRI 343
Score = 36.6 bits (83), Expect = 0.028
Identities = 44/202 (21%), Positives = 81/202 (40%), Gaps = 27/202 (13%)
Query: 48 TQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQE-------KGI 100
T GKK A IPA+ + G + +E+ +E+ + +SE ++ED+ +++ K
Sbjct: 121 TPGKKGAA--IPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAA 178
Query: 101 GSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKET 160
+ A + ++DE D + EE ET+ +K +K +
Sbjct: 179 AAAPASEDEDDE-------DDEDDEDDDDDEEDDSEEEAMETTPAK-------GKKAAKV 224
Query: 161 EKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKR 220
VK V + EE E D ++ + ++++E+ + + P KR
Sbjct: 225 VPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPG----KR 280
Query: 221 SSGMSSLLGKIGAKKQKMSTLE 242
M+ AKKQK+ E
Sbjct: 281 KKEMAKQKAAPEAKKQKVEGTE 302
Score = 36.2 bits (82), Expect = 0.036
Identities = 65/291 (22%), Positives = 119/291 (40%), Gaps = 61/291 (20%)
Query: 10 STSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLS 69
+ +ED D E +DD E ++DE + E++ + + A + PA
Sbjct: 139 NAKKEDSD------EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPAS-------- 184
Query: 70 LEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPP 129
E+E++ED + + E +EEDD+ +E+ + + A+ KK ++ V K+K
Sbjct: 185 -EDEDDED-DEDDEDDDDDEEDDS--EEEAMETTPAKGKKAAKV-------VPVKAKNVA 233
Query: 130 STQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEA 189
+ ++ ++ +E + ++ E +E E+ EE KE A K
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE----------EEEEEPVKE--APGKRK 281
Query: 190 KSFFKQN-----EKEKPQANVPSALPSLPAG------SGLKRSSGMSSLLGK-------- 230
K KQ +K+K + P+ +L G S + +G+S + K
Sbjct: 282 KEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDV 341
Query: 231 -IGAKKQKMSTLEKSKLDWESFKEEEGI---GEELAIHN-RGKEGYIERKA 276
IG ++ +S D E E G+ G E+ + +GK+ ER A
Sbjct: 342 RIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDA 392
Score = 32.3 bits (72), Expect = 0.52
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 10/91 (10%)
Query: 72 EEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPST 131
+E EED SE E S +EEDD++ +E I +K K+ ++ V P KV +T
Sbjct: 22 KEVEED--SEDEEMSEDEEDDSSGEEVVI---PQKKGKKAAATSAKKVVVSPTKKVAVAT 76
Query: 132 QVKK-----GEETEETSSSKLLVKAEELEKP 157
KK G++ T + K + A+ + P
Sbjct: 77 PAKKAAVTPGKKAAATPAKKTVTPAKAVTTP 107
Score = 31.2 bits (69), Expect = 1.2
Identities = 17/64 (26%), Positives = 32/64 (50%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
E+ D E+ E+D+D + EDD E +E+E +E K + + K ++ P
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEA 293
Query: 62 KRRQ 65
K+++
Sbjct: 294 KKQK 297
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 54.7 bits (130), Expect = 1e-07
Identities = 58/258 (22%), Positives = 106/258 (41%), Gaps = 24/258 (9%)
Query: 21 SGGEYSEDDVNELVKEDEVDGE---------EQTQKTQGKKRKAQSIPARKRRQGGLSLE 71
SG E+ +D+ E ++D+ GE E +K + KKR + ++R QG
Sbjct: 664 SGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKER 723
Query: 72 EEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPST 131
+E E+ E G EEE D E+E+ E + + +E+ + G + K +
Sbjct: 724 NQEMEEGGEEEHGEGEEEEGD-REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAG 782
Query: 132 QVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKS 191
+ +KGEE + + E+ +E +V+ +V + GE +E + +E +
Sbjct: 783 KEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEG 842
Query: 192 FFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWESF 251
++ E E+ + G G G + G + + E+ + + E
Sbjct: 843 EEEEGEGEEEE------------GEGKGEEEGEEGEGEEEGEEGEGEG--EEEEGEGEGE 888
Query: 252 KEEEGIGEELAIHNRGKE 269
+E EG GEE G+E
Sbjct: 889 EEGEGEGEEEEGEGEGEE 906
Score = 50.4 bits (119), Expect = 2e-06
Identities = 61/281 (21%), Positives = 115/281 (40%), Gaps = 26/281 (9%)
Query: 14 EDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQ-GKKRKAQ----------SIPARK 62
++E +P E +ED ++E EV+ E+ K G+K K + + K
Sbjct: 581 DEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGK 640
Query: 63 RRQGGLSLEEEEEEDANSESEGSS-----SEEEDDAAEQEKGIG-----SEDARKKKEDE 112
+ G + + E + EGSS +EE + E++KG G E ++ E E
Sbjct: 641 AKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKE 700
Query: 113 LWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFA 172
W + + + Q ++ +E EE + EE +E E+ + +
Sbjct: 701 EWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGE 760
Query: 173 GEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKI- 231
GEEV +E + ++ + + EK + + + G G ++ G G++
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE 820
Query: 232 ---GAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNRGKE 269
G ++++ E + + E +EEEG GEE +G+E
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEG-EEEEGEGEEEEGEGKGEE 860
Score = 45.1 bits (105), Expect = 8e-05
Identities = 41/162 (25%), Positives = 68/162 (41%), Gaps = 15/162 (9%)
Query: 1 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 60
MEE E+ EE+E E E + E + +EV+GE + ++ + KK +
Sbjct: 727 MEEGGEEEHGEGEEEEGDREEEEE-KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Query: 61 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 120
+ +G EEEE + E + E E E+ KG R+++E+E
Sbjct: 786 KGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG-----EREEEEEE-------- 832
Query: 121 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEK 162
G + + ++GE EE K + EE E +E E+
Sbjct: 833 -GEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Score = 45.1 bits (105), Expect = 8e-05
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
Query: 2 EEFDSEDFSTSEEDEDYVPSG-GEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 60
EE + E EE E G GE E + + +E +GEE+ ++ +G+ + +
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886
Query: 61 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDE 112
+ G EEE E + E EG EEE + +E+G E +++E E
Sbjct: 887 GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Score = 44.3 bits (103), Expect = 1e-04
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVK--EDEVDGEEQTQKTQGKKRKAQSIP 59
EE + E E +E+ G E E +V V+ E E +GEE+ + +G++R+ +
Sbjct: 993 EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052
Query: 60 ARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEK 98
RR + EEEEEE+ + G E D E +K
Sbjct: 1053 EENRR----NREEEEEEEGKYQETGEEENERQDGEEYKK 1087
Score = 42.0 bits (97), Expect = 7e-04
Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 2 EEFDSEDFSTSEEDEDYVPSG------GEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKA 55
EE ++E +E+ V G GE E++ +E+E +GEE+ + + ++ +
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEG 856
Query: 56 QSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDE 112
+ + +G EE E E E EG EE + E+E+G G + + E E
Sbjct: 857 KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGE 913
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/169 (24%), Positives = 70/169 (41%), Gaps = 11/169 (6%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
EE + E E E GE E++ +E+ +GE + ++ +G+
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG 948
Query: 62 KRRQGGLSLEEEEEE-DANSESEG------SSSEEEDDAAEQEKGIGSEDARKKKEDELW 114
+ +G EEEE E + E EG EEE+ E E+ G E+ ++ E E
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Query: 115 ASFLNDVGPKSKVPPSTQVKKGE-ETEETSSSKLLVKAEELEKPKETEK 162
+ + +V + ++GE E EE + + EE EK E E+
Sbjct: 1009 GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE---EGEEREKEGEGEE 1054
Score = 39.3 bits (90), Expect = 0.004
Identities = 46/204 (22%), Positives = 83/204 (40%), Gaps = 6/204 (2%)
Query: 3 EFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARK 62
E + E+ EE E+ G E++ E E+E +GE + ++ +G+ + +
Sbjct: 859 EEEGEEGEGEEEGEE----GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914
Query: 63 RRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVG 122
G EE EE + E E E ED E E+ G + +++ + G
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974
Query: 123 PKSKVPPSTQVKKGEETEETSSSKLLVKAE-ELEKPKETEKVKITKV-FDFAGEEVRVTK 180
+ + + +GE EE + + E E E E E+ + +V + GEE
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG 1034
Query: 181 EVDATSKEAKSFFKQNEKEKPQAN 204
E + +E + K+ E E+ + N
Sbjct: 1035 EEEEGEEEGEEREKEGEGEENRRN 1058
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/162 (22%), Positives = 66/162 (40%), Gaps = 13/162 (8%)
Query: 3 EFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARK 62
E + ED E+E+ G E E+ E +E E +GEE + + ++ + +
Sbjct: 938 EGEGEDGEGEGEEEEGEWEGEE--EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEG 995
Query: 63 RRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVG 122
+G E EEE + E E E + E+ +G G E+ +++ +E
Sbjct: 996 EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE---------- 1045
Query: 123 PKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVK 164
+ K + ++ E EE K EE + ++ E+ K
Sbjct: 1046 -REKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYK 1086
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/226 (19%), Positives = 90/226 (39%), Gaps = 11/226 (4%)
Query: 7 EDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQG 66
E+ + +E+ GE E++ ++ E +GEE+ + +G++ + + + +G
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG-EGEEEGEG 972
Query: 67 ------GLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 120
G EEE E + E EEE + E+ +G G E+ + E E+
Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032
Query: 121 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK 180
G + + + ++ E E + + EE K +ET + + + GEE +
Sbjct: 1033 EGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ---DGEEYKKVS 1089
Query: 181 EVDATSKEAK-SFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMS 225
++ + K K +++ Q N +P S +G S
Sbjct: 1090 KIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPS 1135
Score = 37.0 bits (84), Expect = 0.021
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 18/113 (15%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDE--VDGEEQTQKTQGKKRKAQSIP 59
EE + E EE E+ GE E+ E +E+E V+GE + ++ +G+ +
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE----- 1036
Query: 60 ARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDE 112
EE EEE E EG E + E+E+ G ++E+E
Sbjct: 1037 -----------EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENE 1078
Score = 32.0 bits (71), Expect = 0.68
Identities = 31/118 (26%), Positives = 51/118 (43%), Gaps = 11/118 (9%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSED-DVNELVKEDEVDGEEQTQKTQGKKR-----KA 55
EE + E+ E+E+ G E E+ + E +E E +GEE+ + +G++ +
Sbjct: 838 EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Query: 56 QSIPARKRRQG-GLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDE 112
+ +G G EEE E E E E E++ E E ED + E+E
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE----GEDGEGEGEEE 951
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 53.1 bits (126), Expect = 3e-07
Identities = 60/272 (22%), Positives = 100/272 (36%), Gaps = 32/272 (11%)
Query: 16 EDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEE 75
E + + G ++ + D D E+ ++ QG K ++PA++ +
Sbjct: 65 ERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKAS 124
Query: 76 EDANSESEGSSSEEEDDAAE--------QEKGIGSEDARKKKEDELWASFLNDVGPKSKV 127
E ++SE +EED + Q K + + K D S D PK++
Sbjct: 125 ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184
Query: 128 PPSTQVK---------------------KGEETEETSSSKLLVKAEELEKPKETEKVKIT 166
P T V K + +SSS E EK T K +
Sbjct: 185 PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 167 K--VFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGM 224
K V A + T ++S E S ++ E++KP N P S+P S +
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 225 SSLLGKIGAKKQK-MSTLEKSKLDWESFKEEE 255
+ K +KQ+ + + E S + +S EEE
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEE 336
Score = 43.9 bits (102), Expect = 2e-04
Identities = 43/148 (29%), Positives = 62/148 (41%), Gaps = 20/148 (13%)
Query: 20 PSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDAN 79
P G S D + E+E EE+T K+ KK K Q + S ++ + E +N
Sbjct: 463 PQGSRDSSSDSDSSSSEEE---EEKTSKSAVKK-KPQKVAGGAAPSKPASAKKGKAESSN 518
Query: 80 SESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEET 139
S S SSEEE+ E+ KG GS + K + G + + + K E
Sbjct: 519 SSSSDDSSEEEE---EKLKGKGSPRPQAPKAN----------GTSALTAQNGKAAKNSEE 565
Query: 140 EETSSSKLLV---KAEELEKPKETEKVK 164
EE K V K+ L+K K+ E K
Sbjct: 566 EEEEKKKAAVVVSKSGSLKKRKQNEAAK 593
Score = 43.5 bits (101), Expect = 2e-04
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 29/180 (16%)
Query: 26 SEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGS 85
S ++ + +E++ T K + + A S+PA++ QG D++S+S+ S
Sbjct: 425 SSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQG--------SRDSSSDSDSS 476
Query: 86 SSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSS 145
SSEEE++ S+ A KKK ++ G P S + K E + +SS
Sbjct: 477 SSEEEEEKT-------SKSAVKKKPQKVAG------GAAPSKPASAKKGKAESSNSSSSD 523
Query: 146 KLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANV 205
+ EE K K + + + K T + A + +A ++ E+EK +A V
Sbjct: 524 DSSEEEEEKLKGKGSPRPQAPK--------ANGTSALTAQNGKAAKNSEEEEEEKKKAAV 575
Score = 42.0 bits (97), Expect = 7e-04
Identities = 69/317 (21%), Positives = 108/317 (34%), Gaps = 64/317 (20%)
Query: 2 EEFDSEDFSTSEEDEDY-----------------VPSGGEYSEDDVNELVKEDEVDGEEQ 44
E SE+ S +++ED P S D ++ EDE ++
Sbjct: 125 ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184
Query: 45 ---TQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGI- 100
T T + KA PAR + ++S S SEEE AA +K +
Sbjct: 185 PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 101 ---------------------GSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEET 139
SED+ +E+E N GP S VPP + +
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 140 EETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVR-------VTKEVDATSKEAKSF 192
K + K + +E +++ D + EE + V+K K+
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDES-----DSSSEEEKKPPTKAVVSKATTKPPPAKKAA 359
Query: 193 FKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGK------IGAKKQKMSTLEK--- 243
++ ++ PS PAG+ K SS ++ K A KQ + +K
Sbjct: 360 ESSSDSSDSDSSEDDEAPSKPAGT-TKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418
Query: 244 SKLDWESFKEEEGIGEE 260
K D S +EE EE
Sbjct: 419 RKADSSSSEEESSSSEE 435
Score = 37.0 bits (84), Expect = 0.021
Identities = 64/263 (24%), Positives = 97/263 (36%), Gaps = 42/263 (15%)
Query: 5 DSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRR 64
DS D +SE+DE G V T K+ K PA +
Sbjct: 364 DSSDSDSSEDDEAPSKPAGTTKNSSNKPAV----------TTKSPAVK------PAAAPK 407
Query: 65 Q---GGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDEL-WASFLND 120
Q GG L + + ++SE E SSSEEE + +K + + + + L +
Sbjct: 408 QPVGGGQKLLTRKADSSSSEEESSSSEEE----KTKKMVATTKPKATAKAALSLPAKQAP 463
Query: 121 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEEL------EKPKETEKVKITKVFDFAGE 174
G + S EE E+TS S + K +++ KP +K K
Sbjct: 464 QGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGK---------A 514
Query: 175 EVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPA--GSGLKRSSGMSSLLGKIG 232
E + D +S+E + K +PQA + +L A G K S K
Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAA 574
Query: 233 AKKQKMSTLEKSKLDWESFKEEE 255
K +L+K K + E+ KE E
Sbjct: 575 VVVSKSGSLKKRKQN-EAAKEAE 596
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 52.4 bits (124), Expect = 5e-07
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 17/214 (7%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKK----RKAQS 57
EE E+ ++E+E GGE +E+ GEE+T+ ++ K
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGE----------EEEAEGGEEETKSPPAEEAASPEKEAK 517
Query: 58 IPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASF 117
P ++ + + E+E+A S +E S E+ A++E E +KE+ +
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE 577
Query: 118 LNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVR 177
+ K+K P + K E + +K VK EE + P E K + + E
Sbjct: 578 VKS-PEKAKSPAKEEAKSPAEAKSPEKAKSPVK-EEAKSPAEA-KSPVKEEAKSPAEVKS 634
Query: 178 VTKEVDATSKEAKSFFKQNEKEKPQANVPSALPS 211
K T +EAKS K EK +A P S
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668
Score = 43.5 bits (101), Expect = 2e-04
Identities = 51/216 (23%), Positives = 84/216 (38%), Gaps = 22/216 (10%)
Query: 30 VNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEE 89
V E +++ V EEQT++TQ + + EEEE++A E +E
Sbjct: 446 VVEKSEKETVIVEEQTEETQVTEE----------------VTEEEEKEAKEEE----GKE 485
Query: 90 EDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLV 149
E+ E+E G E+ + +E + P + S K E EE S +
Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545
Query: 150 KAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSAL 209
E+ + P + E + EE + EV + K AKS K+ K +A P
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK-AKSPAKEEAKSPAEAKSPEKA 604
Query: 210 PSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSK 245
S P K + S + + ++ + EK+K
Sbjct: 605 KS-PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK 639
Score = 42.7 bits (99), Expect = 4e-04
Identities = 57/217 (26%), Positives = 87/217 (40%), Gaps = 31/217 (14%)
Query: 7 EDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKK-RKAQSIPARKRRQ 65
++ EE + V + E V E K+ E + T KT+ KK K + P ++ +
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871
Query: 66 GGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKS 125
+ EE++E A + + S E + + AE +K + + + KE D PK
Sbjct: 872 PKV---EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE----KEAPAKVEVKEDAKPKE 924
Query: 126 KVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDAT 185
K T+V K E + KA+E KP E ++ A E + TKE A
Sbjct: 925 K----TEVAKKEPDD--------AKAKEPSKPAEKKE---------AAPEKKDTKEEKAK 963
Query: 186 SKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSS 222
E K K K K S PS P ++SS
Sbjct: 964 KPEEKP--KTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998
Score = 39.3 bits (90), Expect = 0.004
Identities = 38/167 (22%), Positives = 63/167 (37%), Gaps = 13/167 (7%)
Query: 36 EDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAE 95
++EV E+ + + KA K+ + ++EEE+ E EE+ A
Sbjct: 790 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849
Query: 96 QEKGIGSEDARKKKEDELWASFLNDVGPKSKVP-PSTQVKKGEETEETSSSKLLVKAEEL 154
K +D++K++ PK + P P + KK E+ SK+ K EE
Sbjct: 850 TPKTEEKKDSKKEE------------APKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 155 EKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKP 201
E K+ + +E KE +K+ K E KP
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944
Score = 36.6 bits (83), Expect = 0.028
Identities = 64/297 (21%), Positives = 103/297 (34%), Gaps = 47/297 (15%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYS--EDDVNELVKED--------EVDGEEQTQKTQGK 51
EE E+ + E+E P E + E + VKE+ + EE + K
Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545
Query: 52 KRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQE-------------- 97
+ PA++ + + E+E+A S +E S E+ A++E
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605
Query: 98 -------------KGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSS 144
K E+A+ E + + ++K P + + EE +
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Query: 145 SKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQAN 204
+K VKAE K VK E K +EAKS K K +A
Sbjct: 666 AKSPVKAEAKSPEKAKSPVK--------AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717
Query: 205 VPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSK-LDWESFKEEEGIGEE 260
P S P K S + + +K + EK+K LD +S + + EE
Sbjct: 718 SPEKAKS-PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Score = 35.8 bits (81), Expect = 0.047
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 3/128 (2%)
Query: 35 KEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAA 94
KE V+ +++ K + KK +A+ + + E +EDA + + +++E D A
Sbjct: 878 KEPAVEKPKES-KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936
Query: 95 EQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEEL 154
+ ++ S+ A KK+ + K + P T+ K E+ + S KAE+
Sbjct: 937 KAKEP--SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKA 994
Query: 155 EKPKETEK 162
EK T++
Sbjct: 995 EKSSSTDQ 1002
Score = 34.7 bits (78), Expect = 0.10
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 9/136 (6%)
Query: 71 EEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPS 130
EE+ + SE E EE+ + + + + E+ ++ KE+E + G + +
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEE---GKEEEGGEEEEAEGG 497
Query: 131 TQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAK 190
+ K EE +S + K+ E+ K + K + EE + EV + K AK
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE-----KEEAKSPAEVKSPEK-AK 551
Query: 191 SFFKQNEKEKPQANVP 206
S K+ K P+A P
Sbjct: 552 SPAKEEAKSPPEAKSP 567
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 50.1 bits (118), Expect = 2e-06
Identities = 48/235 (20%), Positives = 103/235 (43%), Gaps = 16/235 (6%)
Query: 34 VKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEE----EEEDANSESEGSSSEE 89
V+E E EQ + + ++ + + + R Q G E+E E+E E EG E+
Sbjct: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
Query: 90 EDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLV 149
E EQE +G ++ + +++E +G + + + + GE+ E+ + V
Sbjct: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
Query: 150 KAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSAL 209
+ +E + K+ E+++ + E++R +E KE +Q +++ Q
Sbjct: 251 QKQEEQMRKQEEQMREQE------EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Query: 210 PSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWES----FKEEEGIGEE 260
++ M ++G ++++M E+ + WE +K+EE +GE+
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEEQM--WEQKEQMWEQKEQMWKQEEQMGEQ 357
Score = 45.1 bits (105), Expect = 8e-05
Identities = 33/197 (16%), Positives = 89/197 (45%), Gaps = 14/197 (7%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
E+ ++ E++E + E + +E++V +E+ + Q ++ + Q R
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272
Query: 62 KRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDV 121
++ + L +E+ E+ E + E+E+ EQE+ + ++ + ++++E +
Sbjct: 273 EQEEQMLKQKEQTEQ------EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326
Query: 122 GPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKE 181
G + + + + E+ E+ + + +E + K+ E+V+ +E ++ K+
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR--------KQEEQMRKQ 378
Query: 182 VDATSKEAKSFFKQNEK 198
+ K+ + KQ E+
Sbjct: 379 EEQMRKQEEQMRKQEEQ 395
Score = 42.7 bits (99), Expect = 4e-04
Identities = 47/265 (17%), Positives = 113/265 (42%), Gaps = 37/265 (13%)
Query: 3 EFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVD-GEEQTQKTQGKKRKAQSIPAR 61
+ ++ E++E + E + +E+++ EEQ QK + + +K + +
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259
Query: 62 KRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDV 121
+ Q E+ E++ + +E+E+ EQE+ + ++ + ++++E
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE--------- 310
Query: 122 GPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKE---TEKVKITKVFDFAGE-EVR 177
Q+++ EE ++ + E++ + KE +K ++ K + GE E +
Sbjct: 311 ----------QMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 178 VTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQK 237
+ K+ + K+ + KQ E+ + Q K+ M ++G +K++
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEE-----------QMRKQEEQMGEQKEQMGEQKEQ 409
Query: 238 MSTLEK--SKLDWESFKEEEGIGEE 260
M E+ + + K+EE +GE+
Sbjct: 410 MREQEEQMGEQKEQMRKQEEHMGEQ 434
Score = 37.4 bits (85), Expect = 0.016
Identities = 37/201 (18%), Positives = 85/201 (42%), Gaps = 8/201 (3%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
EE E ++ E+ V E ++ +++E E++ Q + K++ Q
Sbjct: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
Query: 62 KRRQGGLSLEEE--EEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLN 119
++ + EE+ E+E+ E E E+E+ +QE+ + + + ++ E
Sbjct: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Query: 120 DVGPKSK--VPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVR 177
+G + + QV+K EE ++ + E++ K +E ++ + + GE+
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE----QMGEQKEQMGEQKE 408
Query: 178 VTKEVDATSKEAKSFFKQNEK 198
+E + E K ++ E+
Sbjct: 409 QMREQEEQMGEQKEQMRKQEE 429
Score = 32.3 bits (72), Expect = 0.52
Identities = 48/274 (17%), Positives = 113/274 (41%), Gaps = 32/274 (11%)
Query: 31 NELVKEDEVDGEEQTQKTQGKKRKAQ---SIPARKRRQGGLSLEEE----EEEDANSESE 83
NE +KE + +E+ Q + +K + Q RK + L +E E+E E E
Sbjct: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
Query: 84 GSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETS 143
G E+E EQE + ++ + ++++ G + + ++G+ E+
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQE---GQVREQEGQVREQEGQVREQEGQVREQEG 122
Query: 144 SSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNE----KE 199
V+ +E + ++ +V+ E+ +E + +E + ++ E ++
Sbjct: 123 Q----VREQEGQVREQEGQVR---------EQEGQVREQEGQVREQEGQVREQEGQVREQ 169
Query: 200 KPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGE 259
+ Q G ++ M G++G ++++M E+ + K+EE +GE
Sbjct: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE-----QMQKQEEQMGE 224
Query: 260 ELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLR 293
+ + +E E++ + + + + + E +R
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 50.1 bits (118), Expect = 2e-06
Identities = 44/164 (26%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Query: 54 KAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEE-DDAAEQEKGIGSEDARKKKEDE 112
+A I A KRRQ L E+EE+E E + EE AE+E+ E+ARK++E+
Sbjct: 399 EAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER 458
Query: 113 LWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEE---------LEKPKETEKV 163
K K + K GEE + + +LL+K ++ +EK KE +
Sbjct: 459 -----KRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAET 513
Query: 164 KITKVFD-FAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVP 206
K +V + E ++ +++ E K + K +++VP
Sbjct: 514 KAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVP 557
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/177 (24%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 36 EDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAE 95
+ E + +E+ +K + + + + + RK + L LEEE + E E EEE E
Sbjct: 414 QKEQEEQERVEKEEQDRLEREELK-RKAEEERLRLEEEARKQ---EEERKRQEEEKKKQE 469
Query: 96 -QEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEEL 154
+EK E+A++K E+EL + + K ++K +E ET KA E+
Sbjct: 470 GEEKRKAGEEAKRKAEEELLLKEKQEQEKQEK----AMIEKQKEAAET-------KAREV 518
Query: 155 EKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAK--SFFKQNEKEKPQANVPSAL 209
+ E+ +I + E + K +D K + Q +KE P+ V A+
Sbjct: 519 AEQMRLEREQI--MLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPKVGVQPAV 573
Score = 39.7 bits (91), Expect = 0.003
Identities = 56/250 (22%), Positives = 105/250 (42%), Gaps = 26/250 (10%)
Query: 69 SLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVP 128
+L ++ +E E S+ E E A+Q G E+A +K + AS + K
Sbjct: 323 ALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAE 382
Query: 129 PSTQVKK--------GEE----TEETSSSKLLVKAEELEKPKETEKVKITK-VFDFAGEE 175
S + K GE E+ ++L + EE E+ ++ E+ ++ + EE
Sbjct: 383 NSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEE 442
Query: 176 VRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLL-GKIGAK 234
R+ E +A +E + ++ EK+K + AG KR + LL K +
Sbjct: 443 ERLRLEEEARKQEEERKRQEEEKKKQEGE-----EKRKAGEEAKRKAEEELLLKEKQEQE 497
Query: 235 KQKMSTLEKSKLDWESFKEEEGIGEELAIHNRG-----KEGYIERKAFLDRVDHRQFEIE 289
KQ+ + +EK K E+ E + E++ + ++ +ERK +D + R + +
Sbjct: 498 KQEKAMIEKQKEAAETKARE--VAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSD 555
Query: 290 RDLRLSKMKP 299
++ K P
Sbjct: 556 VPPQVKKEDP 565
Score = 31.2 bits (69), Expect = 1.2
Identities = 21/110 (19%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Query: 1 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 60
+++ E +E++D + + + L E+E +E+ +K Q +++K Q
Sbjct: 413 LQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQE--G 470
Query: 61 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKE 110
++R+ G + + EE+ + + ++E E++K AR+ E
Sbjct: 471 EEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAE 520
>gi|5453904 RAD51 associated protein 1 isoform b [Homo sapiens]
Length = 335
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/214 (22%), Positives = 88/214 (41%), Gaps = 38/214 (17%)
Query: 29 DVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSE----SEG 84
D++++ ED+V G QGK++ A A++R+ + LE + + AN + G
Sbjct: 136 DLDKITVEDDVGG------VQGKRKAASKAAAQQRK---ILLEGSDGDSANDTEPDFAPG 186
Query: 85 SSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSS 144
SE++ D E E RK K E+ K +V + V+K E+ ++
Sbjct: 187 EDSEDDSDFCESEDNDEDFSMRKSKVKEI---------KKKEVKVKSPVEKKEKKSKSKC 237
Query: 145 SKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQAN 204
+ L+ + ++E + K + + R E+ + S E+K
Sbjct: 238 NALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKK------------- 284
Query: 205 VPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKM 238
P +P PA SG RSS ++ + + Q +
Sbjct: 285 -PKWVP--PAASGGSRSSSSPLVVVSVKSPNQSL 315
>gi|195947391 RAD51 associated protein 1 isoform a [Homo sapiens]
Length = 352
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/214 (22%), Positives = 88/214 (41%), Gaps = 38/214 (17%)
Query: 29 DVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSE----SEG 84
D++++ ED+V G QGK++ A A++R+ + LE + + AN + G
Sbjct: 153 DLDKITVEDDVGG------VQGKRKAASKAAAQQRK---ILLEGSDGDSANDTEPDFAPG 203
Query: 85 SSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSS 144
SE++ D E E RK K E+ K +V + V+K E+ ++
Sbjct: 204 EDSEDDSDFCESEDNDEDFSMRKSKVKEI---------KKKEVKVKSPVEKKEKKSKSKC 254
Query: 145 SKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQAN 204
+ L+ + ++E + K + + R E+ + S E+K
Sbjct: 255 NALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKK------------- 301
Query: 205 VPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKM 238
P +P PA SG RSS ++ + + Q +
Sbjct: 302 -PKWVP--PAASGGSRSSSSPLVVVSVKSPNQSL 332
>gi|126362983 ribosomal RNA processing 15 homolog [Homo sapiens]
Length = 282
Score = 49.7 bits (117), Expect = 3e-06
Identities = 64/252 (25%), Positives = 100/252 (39%), Gaps = 42/252 (16%)
Query: 36 EDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEE------ 89
+ V EE +KT KK K + G ++ E+E S+SEGS E
Sbjct: 7 DSRVSEEENLKKTPKKKMKMVT--------GAVASVLEDEATDTSDSEGSCGSEKDHFYS 58
Query: 90 EDDAAEQEKGIGSEDARKKKED-------------ELWASFLNDVGPKSKVPPSTQVKKG 136
+DDA E + +E K+ E+ + A LN P+SK + KK
Sbjct: 59 DDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKL 118
Query: 137 EETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQN 196
E+ +E + L K ++ +K E E + K +E + AT + F N
Sbjct: 119 EKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLF---N 175
Query: 197 EKEKPQANVPSALPSLPAGSGLKRSSGM----------SSLLGKIGAKKQKMSTLEKSKL 246
+K Q NV + AGS +++ + + S L G G+ + S+ +K K
Sbjct: 176 AVQKHQKNVDEKVKE--AGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKA 233
Query: 247 DWESFKEEEGIG 258
K EEG G
Sbjct: 234 KQTEVKSEEGPG 245
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 49.7 bits (117), Expect = 3e-06
Identities = 56/213 (26%), Positives = 95/213 (44%), Gaps = 29/213 (13%)
Query: 21 SGGEYSEDDVNELVKEDEVDGEEQT---QKTQGKKRKAQSIPAR-KRRQGGLSLEEE--E 74
+GG+ ED EL KED + EE T Q+ G+K + +S P + ++ L+ E++ E
Sbjct: 102 AGGK--EDAEAELKKEDG-EKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAE 158
Query: 75 EEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVK 134
E++A ES + + D E + + EDA+ ++E G + + + K
Sbjct: 159 EKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEE--------TGQRKECSTEPKEK 210
Query: 135 KGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEV-DATSKEAKSFF 193
+E + S K +V+ E +PKE + + K A EE +E DA E S
Sbjct: 211 ATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAK--HGAKEEADAKEEAEDAEEAEPGSPS 268
Query: 194 KQNEKE---KPQANV------PSALPSLPAGSG 217
++ E++ +P+ P P P G G
Sbjct: 269 EEQEQDVEKEPEGGAGVIPSSPEEWPESPTGEG 301
Score = 37.0 bits (84), Expect = 0.021
Identities = 62/282 (21%), Positives = 109/282 (38%), Gaps = 39/282 (13%)
Query: 7 EDFSTSEEDEDYVPSGGEYSEDD--VNELVKEDEVDG----EEQTQKTQGK--------- 51
E ++E E G+ SED V+ E+ G E+T+ T GK
Sbjct: 8 ESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTE 67
Query: 52 KRKAQSIPARKRRQGGLSLEE--------EEEEDANSESEGSSSEEEDDAAEQEKGIGSE 103
K + PA L E E + +A + + + +++D ++E +GS+
Sbjct: 68 SGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQ 127
Query: 104 DARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKV 163
+ +KE+ S + K S + +K EE E S A + +KP+ V
Sbjct: 128 EMTGRKEET--KSEPKEAEEKESTLAS-EKQKAEEKEAKPESGQKADANDRDKPEPKATV 184
Query: 164 KITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSG 223
+ + EE KE KE K+ ++ + E +A V + P K G
Sbjct: 185 EEEDAKTASQEETGQRKECSTEPKE-KATDEEAKAESQKAVVEDEAKAEP-----KEPDG 238
Query: 224 MSSLLGKIGAK-----KQKMSTLEKSKLDWESFKEEEGIGEE 260
K GAK K++ E+++ S ++E+ + +E
Sbjct: 239 KEE--AKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKE 278
Score = 35.4 bits (80), Expect = 0.061
Identities = 47/232 (20%), Positives = 90/232 (38%), Gaps = 27/232 (11%)
Query: 14 EDEDYVPSGGEYSE----DDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLS 69
E+++ P G+ ++ D +E D + +Q+ G++++ + P K +
Sbjct: 158 EEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEK------A 211
Query: 70 LEEE---EEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSK 126
+EE E + A E E + +E D E+ K E+A K+E E D
Sbjct: 212 TDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAE-------DAEEAEP 264
Query: 127 VPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATS 186
PS + ++ E E + ++ + E E P+ D G + + + ++
Sbjct: 265 GSPSEEQEQDVEKEPEGGAGVIPSSPE-EWPESPTGEGHNLSTDGLGPDCVASGQTSPSA 323
Query: 187 KEAK-SFFKQNEKEKPQA-----NVPSALPSLPAGSGLKRSSGMSSLLGKIG 232
E+ S Q+ E P + P S PA R+ +++ K G
Sbjct: 324 SESSPSDVPQSPPESPSSGEKKEKAPERRVSAPARPRGPRAQNRKAIVDKFG 375
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 48.9 bits (115), Expect = 5e-06
Identities = 60/259 (23%), Positives = 113/259 (43%), Gaps = 36/259 (13%)
Query: 6 SEDFSTSEEDEDYV-PSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRR 64
S D TS+ D+++ S + ++ K+ + + + G K S +
Sbjct: 92 SSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPE 151
Query: 65 QGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDAR--------KKKEDELWAS 116
+G +S + ++S+S+ SS +EE E +G E+ R K++E EL+
Sbjct: 152 EGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELF-- 209
Query: 117 FLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEV 176
N + + + ++KK +T + K K +E +E EK K+T++ +E
Sbjct: 210 --NRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQE----EEQEKKKLTQI-----QES 258
Query: 177 RVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQ 236
+VT +KE +S K++EK ++ L + KR + + LL AKKQ
Sbjct: 259 QVTSH----NKERRS--KRDEKLDKKSQAMEELKA----EREKRKNRTAELL----AKKQ 304
Query: 237 KMSTLEKSKLDWESFKEEE 255
+ T E D E ++++
Sbjct: 305 PLKTSEVYSDDEEEEEDDK 323
Score = 42.0 bits (97), Expect = 7e-04
Identities = 40/210 (19%), Positives = 87/210 (41%), Gaps = 21/210 (10%)
Query: 6 SEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQ 65
S D +S EDE++ GE D + + +++ +E+ Q+ + K + + R +
Sbjct: 166 SSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIK 225
Query: 66 GGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGS--EDARKKKEDELWASFLNDVGP 123
L +++E+ + + E++ QE + S ++ R K++++L
Sbjct: 226 KKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKL---------- 275
Query: 124 KSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVD 183
KK + EE + + K E + + +K ++V+ EE K +
Sbjct: 276 ---------DKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSE 326
Query: 184 ATSKEAKSFFKQNEKEKPQANVPSALPSLP 213
+ + +++ E+EK + S SLP
Sbjct: 327 KSDRSSRTSSSDEEEEKEEIPPKSQPVSLP 356
Score = 30.8 bits (68), Expect = 1.5
Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
+E + E ++ E V S + +E + + EE + + +K + + A+
Sbjct: 243 QEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAK 302
Query: 62 KRRQGGLSL----EEEEEEDANSESEGSSSEEEDDAAEQEK 98
K+ + EEEEE+D +SE SS E+EK
Sbjct: 303 KQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEK 343
Score = 28.1 bits (61), Expect = 9.8
Identities = 26/129 (20%), Positives = 52/129 (40%), Gaps = 13/129 (10%)
Query: 5 DSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQT-QKTQGKKRKAQSIPARKR 63
+ ++ +E+E + E V KE +E+ +K+Q + RK
Sbjct: 235 EKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKN 294
Query: 64 RQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGP 123
R L +++ + + S+ EEEDD + ++ S + +E+E
Sbjct: 295 RTAELLAKKQPLKTSEVYSD-DEEEEEDDKSSEKSDRSSRTSSSDEEEE----------- 342
Query: 124 KSKVPPSTQ 132
K ++PP +Q
Sbjct: 343 KEEIPPKSQ 351
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 48.1 bits (113), Expect = 9e-06
Identities = 45/225 (20%), Positives = 92/225 (40%), Gaps = 13/225 (5%)
Query: 27 EDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSS 86
EDD+ + GEE + + KK+ + RK+++ S +E E+ + + EG
Sbjct: 211 EDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQE 270
Query: 87 SEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSK 146
+ D + + A+ +++E GPK S ++ EE + K
Sbjct: 271 VDYMSDGSSSSQEEPESKAKAPQQEE---------GPKGVDEQSDSSEESEEEKPPEEDK 321
Query: 147 LLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQ--AN 204
+ ++ P+E ++ K + + EE + E + AK + KP ++
Sbjct: 322 EEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSS 381
Query: 205 VPSALPSLPAGSGLKRSSGMSSLLGKI--GAKKQKMSTLEKSKLD 247
++ P P+ G SS + + K+ G + +M ++ +LD
Sbjct: 382 RGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLD 426
Score = 39.7 bits (91), Expect = 0.003
Identities = 49/227 (21%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 5 DSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRR 64
D E F S++ G++ +V+ + DG +Q+ K KA P ++
Sbjct: 254 DDEAFEDSDD--------GDFEGQEVDYMS-----DGSSSSQEEPESKAKA---PQQEEG 297
Query: 65 QGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPK 124
G+ +E+ D++ ESE EED E+EK + +K+++D
Sbjct: 298 PKGV----DEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDS------------ 341
Query: 125 SKVPPSTQVKKGEETE-ETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVD 183
S + EE++ ++ +S L A++ PK K +G R
Sbjct: 342 -----SEESDSSEESDIDSEASSALFMAKKKTPPKRERKP--------SGGSSRGNSRPG 388
Query: 184 ATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGK 230
S E S + + +PA L+ +G SL GK
Sbjct: 389 TPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGK 435
Score = 28.9 bits (63), Expect = 5.8
Identities = 42/172 (24%), Positives = 67/172 (38%), Gaps = 20/172 (11%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSED--DVNELVKEDEVDGEEQTQKTQGKKRKAQSIP 59
E+ ED EE + P + +D + ++ +E ++D E + KK+ + P
Sbjct: 314 EKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKK---TPP 370
Query: 60 ARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAA---EQEKGIGSEDARKKKEDELWAS 116
R+R+ G S S GS+S AA EQ K + A K+
Sbjct: 371 KRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKR-------- 422
Query: 117 FLNDVGPKSKVPPST-QVKKGEETEETSSSKLLVKAEELEKPKETEKVKITK 167
D GP+S ST Q G+ T + ++ E+ + T K TK
Sbjct: 423 LRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQV---TEDAVRRYLTRKPMTTK 471
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 47.8 bits (112), Expect = 1e-05
Identities = 58/234 (24%), Positives = 98/234 (41%), Gaps = 35/234 (14%)
Query: 3 EFDSEDFSTSEEDEDYVPSGG-----EYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQS 57
E ++E+ +E E+ P G E + V+ E D ++ K + K +
Sbjct: 455 EKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEE 514
Query: 58 IPARKRRQGGLSLEEEEEEDANSESEGSSSEEE--DDAAEQEKGIGSEDARKKKEDELWA 115
K + L+ E EEE ESE SE+E +D +E++ GSE ++ E+
Sbjct: 515 NGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSE---REFEENGLE 571
Query: 116 SFLNDVGPKSKVPPSTQVKKGEET-------EETSSSKLLVKA------EELEKPKETEK 162
L++ G + ++ + K+ EE E+ S K+L + +E KE E+
Sbjct: 572 KDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEE 631
Query: 163 VKITKVFDFAG-----EEVRVTKEVDATSKEA-------KSFFKQNEKEKPQAN 204
KVFD EE K ++A K+A K F + ++KE A+
Sbjct: 632 DTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDAD 685
Score = 33.9 bits (76), Expect = 0.18
Identities = 49/209 (23%), Positives = 78/209 (37%), Gaps = 44/209 (21%)
Query: 5 DSEDFSTSEEDEDYVPSGGEYSEDDVNELVKED-----EVDGEEQTQKTQGKKRKAQSIP 59
+SED E +E+ P+ E EDD + ED DG E+ + G ++
Sbjct: 520 ESEDDLNKESEEEVGPTK-ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEG 578
Query: 60 ARKRRQGGL---SLEEEEEEDANSESEGSSS------------------EEEDDAAEQEK 98
+ K + LEE + E++ E +GS EEE+D E+
Sbjct: 579 SEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKV- 637
Query: 99 GIGSEDARKKKEDELWASFLN-DVGPKSKVPPSTQVKKGEETE------------ETSSS 145
+D +KEDE +A + K K EE++ E +
Sbjct: 638 ---FDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADE 694
Query: 146 KLLVKAEELEKPKETEKVKITKVFDFAGE 174
KL + EK + E+ K+FD + E
Sbjct: 695 KLFEDDDSNEKLFDEEEDSSEKLFDDSDE 723
Score = 30.0 bits (66), Expect = 2.6
Identities = 52/246 (21%), Positives = 90/246 (36%), Gaps = 40/246 (16%)
Query: 67 GLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSK 126
G S +E E+E E+E + ++G ++K+ E+ N V +
Sbjct: 443 GASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEG------NPVRGSEE 496
Query: 127 VPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATS 186
P + KK + + L ++E+ + E+V TK EE KE D
Sbjct: 497 DSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTK----ESEEDDSEKESDEDC 552
Query: 187 KEAKS------FFKQN-----------EKEKPQANVPSALPSLPAGSGLKRSSGMSSLLG 229
E +S F++N EKE + + L + + G +L
Sbjct: 553 SEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLD 612
Query: 230 KIGA----------KKQKMSTLEKSKLDWESFKEEEGIGEEL---AIHNRGKEGYIERKA 276
+ G+ K+++ T EK D KE+E +E A + +EG + K
Sbjct: 613 EEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKL 672
Query: 277 FLDRVD 282
F + D
Sbjct: 673 FEESDD 678
Score = 29.6 bits (65), Expect = 3.4
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 2 EEFDSED--FSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIP 59
EE D+++ F S++ ED G E +D +E + ED+ E+ + + K
Sbjct: 664 EEGDADEKLFEESDDKEDEDADGKEV--EDADEKLFEDDDSNEKLFDEEEDSSEKLFDDS 721
Query: 60 ARKRRQGGLSLEEEEEEDANSESEGSSSEEEDD 92
+ GG EE S SS +++DD
Sbjct: 722 DERGTLGGFGSVEEGPLSTGSSFILSSDDDDDD 754
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 47.8 bits (112), Expect = 1e-05
Identities = 58/234 (24%), Positives = 98/234 (41%), Gaps = 35/234 (14%)
Query: 3 EFDSEDFSTSEEDEDYVPSGG-----EYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQS 57
E ++E+ +E E+ P G E + V+ E D ++ K + K +
Sbjct: 455 EKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEE 514
Query: 58 IPARKRRQGGLSLEEEEEEDANSESEGSSSEEE--DDAAEQEKGIGSEDARKKKEDELWA 115
K + L+ E EEE ESE SE+E +D +E++ GSE ++ E+
Sbjct: 515 NGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSE---REFEENGLE 571
Query: 116 SFLNDVGPKSKVPPSTQVKKGEET-------EETSSSKLLVKA------EELEKPKETEK 162
L++ G + ++ + K+ EE E+ S K+L + +E KE E+
Sbjct: 572 KDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEE 631
Query: 163 VKITKVFDFAG-----EEVRVTKEVDATSKEA-------KSFFKQNEKEKPQAN 204
KVFD EE K ++A K+A K F + ++KE A+
Sbjct: 632 DTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDAD 685
Score = 33.9 bits (76), Expect = 0.18
Identities = 49/209 (23%), Positives = 78/209 (37%), Gaps = 44/209 (21%)
Query: 5 DSEDFSTSEEDEDYVPSGGEYSEDDVNELVKED-----EVDGEEQTQKTQGKKRKAQSIP 59
+SED E +E+ P+ E EDD + ED DG E+ + G ++
Sbjct: 520 ESEDDLNKESEEEVGPTK-ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEG 578
Query: 60 ARKRRQGGL---SLEEEEEEDANSESEGSSS------------------EEEDDAAEQEK 98
+ K + LEE + E++ E +GS EEE+D E+
Sbjct: 579 SEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKV- 637
Query: 99 GIGSEDARKKKEDELWASFLN-DVGPKSKVPPSTQVKKGEETE------------ETSSS 145
+D +KEDE +A + K K EE++ E +
Sbjct: 638 ---FDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADE 694
Query: 146 KLLVKAEELEKPKETEKVKITKVFDFAGE 174
KL + EK + E+ K+FD + E
Sbjct: 695 KLFEDDDSNEKLFDEEEDSSEKLFDDSDE 723
Score = 30.0 bits (66), Expect = 2.6
Identities = 52/246 (21%), Positives = 90/246 (36%), Gaps = 40/246 (16%)
Query: 67 GLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSK 126
G S +E E+E E+E + ++G ++K+ E+ N V +
Sbjct: 443 GASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEG------NPVRGSEE 496
Query: 127 VPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATS 186
P + KK + + L ++E+ + E+V TK EE KE D
Sbjct: 497 DSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTK----ESEEDDSEKESDEDC 552
Query: 187 KEAKS------FFKQN-----------EKEKPQANVPSALPSLPAGSGLKRSSGMSSLLG 229
E +S F++N EKE + + L + + G +L
Sbjct: 553 SEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLD 612
Query: 230 KIGA----------KKQKMSTLEKSKLDWESFKEEEGIGEEL---AIHNRGKEGYIERKA 276
+ G+ K+++ T EK D KE+E +E A + +EG + K
Sbjct: 613 EEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKL 672
Query: 277 FLDRVD 282
F + D
Sbjct: 673 FEESDD 678
Score = 29.6 bits (65), Expect = 3.4
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 2 EEFDSED--FSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIP 59
EE D+++ F S++ ED G E +D +E + ED+ E+ + + K
Sbjct: 664 EEGDADEKLFEESDDKEDEDADGKEV--EDADEKLFEDDDSNEKLFDEEEDSSEKLFDDS 721
Query: 60 ARKRRQGGLSLEEEEEEDANSESEGSSSEEEDD 92
+ GG EE S SS +++DD
Sbjct: 722 DERGTLGGFGSVEEGPLSTGSSFILSSDDDDDD 754
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 47.8 bits (112), Expect = 1e-05
Identities = 50/215 (23%), Positives = 84/215 (39%), Gaps = 45/215 (20%)
Query: 7 EDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDG-----------EEQTQKTQGKKRKA 55
E SE E+ P +E+D ++ +E E +E+ KTQGK RK+
Sbjct: 899 EPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKS 958
Query: 56 QSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWA 115
++ + E E+A+ ES EE+D+ E+++ KKE
Sbjct: 959 FAL-------------DSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKE----- 1000
Query: 116 SFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEE 175
T+V GE+ E SSSK + A+ + T + + +
Sbjct: 1001 ---------------TEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSS 1045
Query: 176 VRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALP 210
+ ++S S + E+E+P A +PSA P
Sbjct: 1046 SSSSSSSSSSSSSESSSEDEEEEERPAA-LPSASP 1079
Score = 36.2 bits (82), Expect = 0.036
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 9/131 (6%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEV-DGEEQTQKTQGKKRKAQSIPA 60
EE E S +E++D E E+ V+ KE EV DGE++ + K S+ A
Sbjct: 966 EEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKC----SLYA 1021
Query: 61 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 120
+ + + +++S S SSS ++ + ++E+E A+ +
Sbjct: 1022 DSDGEN----DSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSA 1077
Query: 121 VGPKSKVPPST 131
P +VP T
Sbjct: 1078 SPPPREVPVPT 1088
Score = 30.4 bits (67), Expect = 2.0
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 37 DEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQ 96
DEV + + ++ K Q + +++R+ G EEE E+ ES SSS + + A +
Sbjct: 1333 DEVLEAPEVVVAEAEEPKPQQL--QQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALR 1390
Query: 97 EKGIGSEDARKK 108
+ + S R++
Sbjct: 1391 RRSLRSHARRRR 1402
>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
Length = 872
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 8 DFSTSEEDEDYVPSGGEYSEDDVN--ELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQ 65
D D+D G+ +E+D + + K+ E DG+++ +K +K +S R R+
Sbjct: 297 DGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356
Query: 66 GGL-SLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPK 124
G S +E ++ SESE +EEE + AE+ ++ K KE+E W + G +
Sbjct: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEE----ALKEKEKPKEEE-WEKPKDAAGLE 411
Query: 125 SKVPP 129
K P
Sbjct: 412 CKPRP 416
Score = 38.9 bits (89), Expect = 0.006
Identities = 39/151 (25%), Positives = 65/151 (43%), Gaps = 22/151 (14%)
Query: 26 SEDDVNELVKEDEVDGEEQ-------TQKTQGKKRKAQSIPARK------RRQGGLSLEE 72
+E+D+ L +E+E EEQ ++K +G+ RK +++ G E
Sbjct: 261 TENDLRILEQEEE---EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
Query: 73 EEEED---ANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPP 129
+ D SE +G E+++D+ ++ K + RK D+ + V
Sbjct: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDE--GSVSESESESE 375
Query: 130 STQV-KKGEETEETSSSKLLVKAEELEKPKE 159
S Q ++ EE EE K K EE EKPK+
Sbjct: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
Score = 33.9 bits (76), Expect = 0.18
Identities = 35/141 (24%), Positives = 57/141 (40%), Gaps = 6/141 (4%)
Query: 65 QGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIG---SEDARKKKEDELWASFLNDV 121
+ L + E+EEE+ + G S++E+ A G G + D +KKED A ND
Sbjct: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAE--NDS 319
Query: 122 GPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKE 181
K S EE +E S K K+ + K + + E + +
Sbjct: 320 SNDDKTKKSEGDGDKEEKKE-DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
Query: 182 VDATSKEAKSFFKQNEKEKPQ 202
+ +EA+ K+ EK K +
Sbjct: 379 AEEEKEEAEEALKEKEKPKEE 399
>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
Length = 876
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 8 DFSTSEEDEDYVPSGGEYSEDDVN--ELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQ 65
D D+D G+ +E+D + + K+ E DG+++ +K +K +S R R+
Sbjct: 297 DGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356
Query: 66 GGL-SLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPK 124
G S +E ++ SESE +EEE + AE+ ++ K KE+E W + G +
Sbjct: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEE----ALKEKEKPKEEE-WEKPKDAAGLE 411
Query: 125 SKVPP 129
K P
Sbjct: 412 CKPRP 416
Score = 38.9 bits (89), Expect = 0.006
Identities = 39/151 (25%), Positives = 65/151 (43%), Gaps = 22/151 (14%)
Query: 26 SEDDVNELVKEDEVDGEEQ-------TQKTQGKKRKAQSIPARK------RRQGGLSLEE 72
+E+D+ L +E+E EEQ ++K +G+ RK +++ G E
Sbjct: 261 TENDLRILEQEEE---EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
Query: 73 EEEED---ANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPP 129
+ D SE +G E+++D+ ++ K + RK D+ + V
Sbjct: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDE--GSVSESESESE 375
Query: 130 STQV-KKGEETEETSSSKLLVKAEELEKPKE 159
S Q ++ EE EE K K EE EKPK+
Sbjct: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
Score = 33.9 bits (76), Expect = 0.18
Identities = 35/141 (24%), Positives = 57/141 (40%), Gaps = 6/141 (4%)
Query: 65 QGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIG---SEDARKKKEDELWASFLNDV 121
+ L + E+EEE+ + G S++E+ A G G + D +KKED A ND
Sbjct: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAE--NDS 319
Query: 122 GPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKE 181
K S EE +E S K K+ + K + + E + +
Sbjct: 320 SNDDKTKKSEGDGDKEEKKE-DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
Query: 182 VDATSKEAKSFFKQNEKEKPQ 202
+ +EA+ K+ EK K +
Sbjct: 379 AEEEKEEAEEALKEKEKPKEE 399
>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
Length = 871
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 9/125 (7%)
Query: 8 DFSTSEEDEDYVPSGGEYSEDDVN--ELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQ 65
D D+D G+ +E+D + + K+ E DG+++ +K +K +S R R+
Sbjct: 297 DGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356
Query: 66 GGL-SLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPK 124
G S +E ++ SESE +EEE + AE K ++K ++E W + G +
Sbjct: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEALK------EKEKPKEEEWEKPKDAAGLE 410
Query: 125 SKVPP 129
K P
Sbjct: 411 CKPRP 415
Score = 39.3 bits (90), Expect = 0.004
Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 21/150 (14%)
Query: 26 SEDDVNELVKEDEVDGEEQ-------TQKTQGKKRKAQSIPARK------RRQGGLSLEE 72
+E+D+ L +E+E EEQ ++K +G+ RK +++ G E
Sbjct: 261 TENDLRILEQEEE---EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
Query: 73 EEEED---ANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPP 129
+ D SE +G E+++D+ ++ K + RK D+ + V
Sbjct: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDE--GSVSESESESE 375
Query: 130 STQVKKGEETEETSSSKLLVKAEELEKPKE 159
S Q ++ +E E K K EE EKPK+
Sbjct: 376 SGQAEEEKEEAEALKEKEKPKEEEWEKPKD 405
Score = 34.7 bits (78), Expect = 0.10
Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 13/147 (8%)
Query: 65 QGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIG---SEDARKKKEDELWASFLNDV 121
+ L + E+EEE+ + G S++E+ A G G + D +KKED A ND
Sbjct: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAE--NDS 319
Query: 122 GPKSKVPPS------TQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEE 175
K S + K+ E E SSK + + + V ++ +G+
Sbjct: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
Query: 176 VRVTKEVDATSKEAKSFFKQNEKEKPQ 202
+E +A ++ K K+ E EKP+
Sbjct: 380 EEEKEEAEALKEKEKP--KEEEWEKPK 404
>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
Length = 875
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 9/125 (7%)
Query: 8 DFSTSEEDEDYVPSGGEYSEDDVN--ELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQ 65
D D+D G+ +E+D + + K+ E DG+++ +K +K +S R R+
Sbjct: 297 DGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356
Query: 66 GGL-SLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPK 124
G S +E ++ SESE +EEE + AE K ++K ++E W + G +
Sbjct: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEALK------EKEKPKEEEWEKPKDAAGLE 410
Query: 125 SKVPP 129
K P
Sbjct: 411 CKPRP 415
Score = 39.3 bits (90), Expect = 0.004
Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 21/150 (14%)
Query: 26 SEDDVNELVKEDEVDGEEQ-------TQKTQGKKRKAQSIPARK------RRQGGLSLEE 72
+E+D+ L +E+E EEQ ++K +G+ RK +++ G E
Sbjct: 261 TENDLRILEQEEE---EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
Query: 73 EEEED---ANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPP 129
+ D SE +G E+++D+ ++ K + RK D+ + V
Sbjct: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDE--GSVSESESESE 375
Query: 130 STQVKKGEETEETSSSKLLVKAEELEKPKE 159
S Q ++ +E E K K EE EKPK+
Sbjct: 376 SGQAEEEKEEAEALKEKEKPKEEEWEKPKD 405
Score = 34.7 bits (78), Expect = 0.10
Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 13/147 (8%)
Query: 65 QGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIG---SEDARKKKEDELWASFLNDV 121
+ L + E+EEE+ + G S++E+ A G G + D +KKED A ND
Sbjct: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAE--NDS 319
Query: 122 GPKSKVPPS------TQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEE 175
K S + K+ E E SSK + + + V ++ +G+
Sbjct: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
Query: 176 VRVTKEVDATSKEAKSFFKQNEKEKPQ 202
+E +A ++ K K+ E EKP+
Sbjct: 380 EEEKEEAEALKEKEKP--KEEEWEKPK 404
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 47.0 bits (110), Expect = 2e-05
Identities = 58/255 (22%), Positives = 104/255 (40%), Gaps = 55/255 (21%)
Query: 7 EDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQG 66
E FS+ ++ + E E ++EL K++ + EE+ ++ +
Sbjct: 2211 EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEE---------------- 2254
Query: 67 GLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSK 126
EE EEE+ E E EEE + + EK E+ +KKK+ E
Sbjct: 2255 ----EEREEEEVREEEEERKEEEEGEEKQVEK---EEEEKKKKKKE-------------- 2293
Query: 127 VPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFA---GEEVRVTKEVD 183
KK EE +E ++ + EE+ +ETE + + + + EEV KE+
Sbjct: 2294 -------KKKEEVQE--KEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL 2344
Query: 184 ATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLK-RSSGMSSLLGKIGA-----KKQK 237
K+ K ++ + + + V S L +P G G R + S L K+ + K++
Sbjct: 2345 KKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKT 2404
Query: 238 MSTLEKSKLDWESFK 252
+ + ++ WE K
Sbjct: 2405 PVPVPEKQISWEDKK 2419
Score = 43.5 bits (101), Expect = 2e-04
Identities = 34/117 (29%), Positives = 63/117 (53%), Gaps = 6/117 (5%)
Query: 1 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKE--DEVDGEE-QTQKTQGKKRKAQS 57
++E + ++ +SEE+E+ E E++V E +E +E +GEE Q +K + +K+K +
Sbjct: 2234 LDELEKQESLSSEEEEEREEEE-EREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK 2292
Query: 58 IPARKRRQGGLSLEEEEEEDANSESEGSSS--EEEDDAAEQEKGIGSEDARKKKEDE 112
++ Q + EE+EE + E S S EEE+++ E+ + E KKE +
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349
Score = 42.0 bits (97), Expect = 7e-04
Identities = 42/188 (22%), Positives = 79/188 (42%), Gaps = 4/188 (2%)
Query: 12 SEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLE 71
+ E+E GG+ +E K +E+ EQ Q +K AQ + + LS +
Sbjct: 1673 AREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQ-EKELAQELEELEWDMEELSWK 1731
Query: 72 EEE---EEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVP 128
EEE EE E + +EEE+ A Q + + E+ + +E+EL + +
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 129 PSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKE 188
P + + G + E+ K+ + + E++ K+ + + + K+ A KE
Sbjct: 1792 PEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Query: 189 AKSFFKQN 196
+ K+N
Sbjct: 1852 KLAQRKEN 1859
Score = 40.8 bits (94), Expect = 0.001
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 36/294 (12%)
Query: 24 EYSEDDVNELVKEDEV--DGEEQTQKTQGKKRKAQSIP--AR-KRRQGGLSLEEEEEEDA 78
E D E+ E+EV +GEE+ Q+ ++R Q AR R++ + +EE
Sbjct: 1535 EQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK 1594
Query: 79 NSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEE 138
++ E ++EE A++E+ + + ++D A K EE
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQK------------EE 1642
Query: 139 TEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEK 198
T KL +AE+L + ++ K KV A EE ++ K+ E K+ Q +
Sbjct: 1643 TLAQRGEKLSQEAEKLAQKRKKLAKKWEKV---AREEEKLAKK-GGKLAEVKNILAQKVE 1698
Query: 199 EKPQANVPSALPSLPAGSGLK-----------RSSGMSSLLGKIGAKKQKMSTLEKSKLD 247
E PQ L+ + ++ GK+ +K+K++ E+ L
Sbjct: 1699 ELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE-EEEALA 1757
Query: 248 WESFK---EEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMK 298
W+ K EE + +E + + KE + K + + R L KMK
Sbjct: 1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMK 1811
Score = 40.4 bits (93), Expect = 0.002
Identities = 63/279 (22%), Positives = 111/279 (39%), Gaps = 40/279 (14%)
Query: 24 EYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESE 83
E S+ D+ E ++ + +K +K++ + R+ + EEE + A SE
Sbjct: 2114 EQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSE 2173
Query: 84 GSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETS 143
+EE+ E+E+ I R +K E G K K S+QV + E+EE
Sbjct: 2174 VILDDEEEGGIEEEEVIPFLKRRWRKRKEA------KRGDKPKEKFSSQVDE-VESEEHF 2226
Query: 144 SSKLLVKAEELEKPKE-TEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQ 202
S ++ +ELEK + + + + + + EE V +E + +E + KQ EKE+ +
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286
Query: 203 ANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELA 262
KK+K E+ + E F+E+E I E
Sbjct: 2287 KK-----------------------------KKKKEKKKEEVQEKEEVFEEKEEIMSEEE 2317
Query: 263 IHNRGKEGYIERKAFLDRVDHRQFEI---ERDLRLSKMK 298
+ E E L+ R+ EI E+ +L + +
Sbjct: 2318 TESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR 2356
Score = 31.2 bits (69), Expect = 1.2
Identities = 52/267 (19%), Positives = 95/267 (35%), Gaps = 41/267 (15%)
Query: 36 EDEVDGEEQTQKTQGKKR---KAQSIPARKRRQGGLSLEEEEEE-----DANSESEGSSS 87
+ ++ GEE G + + S +R L+L +E+ D + SE SS
Sbjct: 1003 QQQMIGEEPLDHLLGMRATDLQILSTQVEQRLNENLTLSHRDEKPAFSLDVSMPSELKSS 1062
Query: 88 -------EEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETE 140
EE + A + KG A KK + W L + ST+ E+
Sbjct: 1063 LKPPTVSEESEVAIKPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPGLLEDES 1122
Query: 141 ETSSSKLLVKAEEL--EKPKETEKVKITKVFDFAG---------------EEVRVTKEVD 183
T ++ + ++ + + T +K++K D +++R ++
Sbjct: 1123 GTEAAPIEMEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKK 1182
Query: 184 ATSKEAKSFFKQNEKEKPQANVPSALPSLP---------AGSGLKRSSGMSSLLGKIGAK 234
AT+++ K K+ KE N + P + G G SG S G +
Sbjct: 1183 ATAQKLKKKHKKKGKEAKVINEETTPPVMEQPVTKKVKIQGRGASGISGRRSTAGDGSSW 1242
Query: 235 KQKMSTLEKSKLDWESFKEEEGIGEEL 261
+ + L ++ K E + EL
Sbjct: 1243 RDDLCRLMALRISGSQTKMSENLNAEL 1269
Score = 28.9 bits (63), Expect = 5.8
Identities = 42/204 (20%), Positives = 78/204 (38%), Gaps = 39/204 (19%)
Query: 73 EEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKED--ELWASFLNDVGPKSKVPPS 130
+EEE + E S EEE + ED + K E+ ++W + L+ + +
Sbjct: 1491 QEEEKLHQAGEKLSPEEE---------MLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE 1541
Query: 131 TQV-------KKGEE------------TEETSSSKLLVKAEELEKPKETEKVKITKVFDF 171
+V ++GEE EE +++ K EK + E+ K+ + +
Sbjct: 1542 EEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK 1601
Query: 172 AGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKI 231
+E R + + +A Q+++E QA A +R +S K+
Sbjct: 1602 LAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLA---QRGEKLSQEAEKL 1658
Query: 232 GAKKQKMSTLEKSKLDWESFKEEE 255
K++K++ WE EE
Sbjct: 1659 AQKRKKLAK------KWEKVAREE 1676
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 8/140 (5%)
Query: 71 EEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGP----KSK 126
EEEEEE+ E E EE++++ Q GS RK K+ W V P + +
Sbjct: 305 EEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKK--WRKDSPWVKPSRKRRKR 362
Query: 127 VPPSTQVKKGEETEETSSSKLLVKAEELEKPK-ETEKVKITKVFDFAGEEVRVTKEVDAT 185
PP + +G + +TSS + EEL E KI ++ + AG + T+ VD
Sbjct: 363 EPPRAKEPRG-VSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGE 421
Query: 186 SKEAKSFFKQNEKEKPQANV 205
+ + E +P + V
Sbjct: 422 LSGCNAAILKRETMRPSSRV 441
Score = 31.2 bits (69), Expect = 1.2
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 13/94 (13%)
Query: 12 SEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQS---------IPARK 62
SEE+E+ E E++ E +EDE G + + +RKA+ P+RK
Sbjct: 299 SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRK 358
Query: 63 RRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQ 96
RR+ E ++ S +SS E + E+
Sbjct: 359 RRK----REPPRAKEPRGVSNDTSSLETERGFEE 388
>gi|157694505 LINE-1 type transposase domain containing 1 [Homo
sapiens]
Length = 865
Score = 47.0 bits (110), Expect = 2e-05
Identities = 64/277 (23%), Positives = 113/277 (40%), Gaps = 49/277 (17%)
Query: 5 DSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRR 64
D ED S EE+E+ PSG E E++ ++EDE G E+ ++ Q+
Sbjct: 396 DDEDTSGLEEEEEE-PSGLEEEEEEEASGLEEDEASGLEEEEE--------QTSEQDSTF 446
Query: 65 QGGLSLEEEEEEDANSES---------EGSSSEEEDDAAEQEKG-----IGSEDARKKKE 110
QG ++ + E + S+ E S SEEE++ E G +E +++
Sbjct: 447 QGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQ 506
Query: 111 DELWASFLNDVGPKSKVPPSTQVKKGEETEETS-------------------SSKLLVKA 151
E+ S+L K K+ V K +E EET+ S L +
Sbjct: 507 KEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSH 566
Query: 152 EELEKPKETE---KVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSA 208
+E +K T +TK+ ++ R + TSKEA + +E +++V ++
Sbjct: 567 DEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEAD--LTEETEENLRSSVINS 624
Query: 209 LPSLPAGSGLKRS--SGMSSLLGKIGAKKQKMSTLEK 243
+ + G +S SG+ + + +M LE+
Sbjct: 625 IREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEE 661
Score = 41.6 bits (96), Expect = 9e-04
Identities = 39/147 (26%), Positives = 65/147 (44%), Gaps = 20/147 (13%)
Query: 24 EYSEDDVNELVK-EDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSES 82
E E++ +EL + ++E G E + T G + + + GL EEEEE E
Sbjct: 375 ETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEE-------PSGLEEEEEEEASGLEED 427
Query: 83 EGSSSEEEDDAAEQE----KGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEE 138
E S EEE++ ++ +G DA+ + E + G ++ S + + EE
Sbjct: 428 EASGLEEEEEQTSEQDSTFQGHTLVDAKHEVE-------ITSDGMETTFIDSVEDSESEE 480
Query: 139 TEETSSSKL-LVKAEELEKPKETEKVK 164
EE SS+ VK L + K + + K
Sbjct: 481 EEEGKSSETGKVKTTSLTEKKASRRQK 507
Score = 29.6 bits (65), Expect = 3.4
Identities = 51/209 (24%), Positives = 84/209 (40%), Gaps = 34/209 (16%)
Query: 23 GEYSEDDVNEL-VKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSE 81
GE + D ++ L +KE +V E+ + + ++ + + G+ E++E+ + E
Sbjct: 348 GEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGM---EDDEDTSGLE 404
Query: 82 SEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPS-----TQVKKG 136
E EEE E+E+ E+A +EDE AS L + ++ S T V
Sbjct: 405 EE----EEEPSGLEEEE---EEEASGLEEDE--ASGLEEEEEQTSEQDSTFQGHTLVDAK 455
Query: 137 EETEETSSSKLLV----------KAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDAT- 185
E E TS + EE K ET KVK T + + + R KE+ +
Sbjct: 456 HEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTE--KKASRRQKEIPFSY 513
Query: 186 ---SKEAKSFFKQNEKEKPQANVPSALPS 211
K K K Q +A+P+
Sbjct: 514 LVGDSGKKKLVKHQVVHKTQEEEETAVPT 542
>gi|9966799 UTP3, small subunit processome component [Homo sapiens]
Length = 479
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/179 (26%), Positives = 77/179 (43%), Gaps = 25/179 (13%)
Query: 31 NELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEE 90
NE+ DE DGEE+ ++ A + GG + EEEEEE N++ +G SS +
Sbjct: 65 NEVQSGDEEDGEEEEEEVL-----ALDMDDEDDEDGGNAGEEEEEE--NADDDGGSSVQS 117
Query: 91 DDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVK 150
+ A + + +K D D G KS+ S Q + EE EE ++++ +
Sbjct: 118 EAEASVDPSLSWGQRKKLYYD-------TDYGSKSRGRQSQQEAEEEEREEEEEAQIIQR 170
Query: 151 AEELEKPKETEKVKITKVFDFA-------GEEVRVTKEVDATSKEAKSFFKQNEKEKPQ 202
L + + + + V FA E RV K++ S + K K KE P+
Sbjct: 171 --RLAQALQEDDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEK--LKMLRKESPE 225
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 46.6 bits (109), Expect = 3e-05
Identities = 45/142 (31%), Positives = 64/142 (45%), Gaps = 27/142 (19%)
Query: 80 SESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEET 139
S+SEGS + ED + + +G S+ E+EL D+ K + Q+K E
Sbjct: 37 SDSEGSGNGSEDASKDSGEGSCSDSEENILEEEL----NEDIKVKEE-----QLKNSAEE 87
Query: 140 EETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKE 199
E SS K L+K +EK +E E GE R KE + ++ K K+ EKE
Sbjct: 88 EVLSSEKQLIK---MEKKEEEEN----------GERPRKKKEKEKEKEKEKEKEKEREKE 134
Query: 200 KPQANV-----PSALPSLPAGS 216
K +A V SA + PA S
Sbjct: 135 KEKATVSENVAASAAATTPATS 156
Score = 39.7 bits (91), Expect = 0.003
Identities = 34/170 (20%), Positives = 69/170 (40%), Gaps = 8/170 (4%)
Query: 6 SEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQ 65
S+ + ED GE S D E + E+E++ + + ++ Q K + + + +++
Sbjct: 37 SDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLSSEKQL 96
Query: 66 GGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKS 125
+ +EEEE + +E++ E+EK E + + + AS S
Sbjct: 97 IKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATS 156
Query: 126 KVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEE 175
PP+ T T++ E++ +PK+ + + DF E
Sbjct: 157 --PPAVNTSPSVPTTTTATE------EQVSEPKKWNLRRNRPLLDFVSME 198
Score = 32.0 bits (71), Expect = 0.68
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 18/127 (14%)
Query: 1 MEEFDSEDFSTSEEDEDYVP--------SGGEYSEDDVNELVKEDEVDGEEQTQKTQGKK 52
MEE + D SE+D D+ P S + D + EDE G ++ + +G
Sbjct: 197 MEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGND 256
Query: 53 RKAQSIPA-----RKRRQGGLSLEEEEEEDANSES-EGSSSEEEDDAAEQEKGIGSEDAR 106
+ S PA +K++ LS ++E+ ++S S S+ +D+ EK S++
Sbjct: 257 -EDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEK---SQNWS 312
Query: 107 KKKEDEL 113
+K D +
Sbjct: 313 SQKMDHI 319
Score = 31.6 bits (70), Expect = 0.89
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 80 SESEGSSSEEEDDAAEQEKGIGS-EDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEE 138
S+ EGS + EDD +++G GS ED + DE +S ++ G K K ++
Sbjct: 227 SQKEGSDGDNEDD---EDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADD 283
Query: 139 TEETSSSKLLVKAEELEKPKETEK 162
E T+ S L +++ E EK
Sbjct: 284 EELTNDSLTLSQSKSNEDSLILEK 307
Score = 30.0 bits (66), Expect = 2.6
Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
Query: 30 VNELVKEDEVDGEEQTQ-KTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSE 88
+ EL D+ D E+ + KRK +S ++K G + ++E+E + E E
Sbjct: 197 MEELNDMDDYDSEDDNDWRPTVVKRKGRSA-SQKEGSDGDNEDDEDEGSGSDEDENDEGN 255
Query: 89 EEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEET 139
+ED ++ +G +KKK L + +D + +Q K E++
Sbjct: 256 DEDHSSPASEG----GCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDS 302
>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
Length = 1726
Score = 46.6 bits (109), Expect = 3e-05
Identities = 59/257 (22%), Positives = 105/257 (40%), Gaps = 32/257 (12%)
Query: 10 STSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLS 69
S +EE E+ GE + V+E++ D EE+ + + QG L
Sbjct: 7 SEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDE-----------QGNLK 55
Query: 70 --LEEEEEEDANSESEGS-SSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSK 126
+ ++++ED E EGS S + EDD +++ S D R ED+ + ++G K K
Sbjct: 56 GFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDR--LEDDDFDLIEENLGVKVK 113
Query: 127 VPPS-TQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVF-DFAGEEVRVTKEVDA 184
+VKK + E+ EE K + ++ ++F D GEE + E
Sbjct: 114 RGQKYRRVKKMSDDEDDDE-------EEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPM 166
Query: 185 TSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKS 244
E + E++ ++++ + G LK+ L G A Q+ +
Sbjct: 167 APPE------EEEEDDEESDIDDFIVD-DDGQPLKKPKWRKKLPGYTDAALQEAQEIFGV 219
Query: 245 KLDWESFKEEEGIGEEL 261
D++ F++ EEL
Sbjct: 220 DFDYDEFEKYNEYDEEL 236
Score = 33.9 bits (76), Expect = 0.18
Identities = 40/207 (19%), Positives = 82/207 (39%), Gaps = 16/207 (7%)
Query: 2 EEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPAR 61
++ + E+ + ++DE G +DD +E +++ D + KKRK S R
Sbjct: 36 DDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDR 95
Query: 62 KRRQGGLSLEEE-----EEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWAS 116
+EE + + S +E+DD E K E ++ +E++
Sbjct: 96 LEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGK---EEHEKEAIAEEIFQD 152
Query: 117 FLNDVGPKSKVPPSTQVKKGEETEETSSSKLLV---KAEELEKPKETEKVKITKVFDFAG 173
+ G ++ P ++ EE +E S + + L+KPK +K+ +
Sbjct: 153 GEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLP-----GYTD 207
Query: 174 EEVRVTKEVDATSKEAKSFFKQNEKEK 200
++ +E+ + F K NE ++
Sbjct: 208 AALQEAQEIFGVDFDYDEFEKYNEYDE 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.300 0.123 0.320
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,174,434
Number of Sequences: 37866
Number of extensions: 644071
Number of successful extensions: 15352
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 485
Number of HSP's successfully gapped in prelim test: 743
Number of HSP's that attempted gapping in prelim test: 4874
Number of HSP's gapped (non-prelim): 4825
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.