Search of human proteins with 5453555

Search of human proteins with 5453555

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453555 ras-related nuclear protein [Homo sapiens]
         (216 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453555 ras-related nuclear protein [Homo sapiens]                 446   e-126
gi|34147513 RAB7, member RAS oncogene family [Homo sapiens]           110   1e-24
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]          109   2e-24
gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]      107   6e-24
gi|34485714 Ras-related protein Rab-23 [Homo sapiens]                 104   7e-23
gi|50234889 RAB43 protein [Homo sapiens]                              104   7e-23
gi|34485716 Ras-related protein Rab-23 [Homo sapiens]                 104   7e-23
gi|19923260 RAB4A, member RAS oncogene family [Homo sapiens]          103   9e-23
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]           103   9e-23
gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo sa...   103   1e-22
gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo sa...   103   1e-22
gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]         102   2e-22
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa...   102   2e-22
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]            102   2e-22
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]            102   2e-22
gi|4759012 RAB9A, member RAS oncogene family [Homo sapiens]           102   3e-22
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]           102   3e-22
gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens]          101   4e-22
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]          100   9e-22
gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens]           100   9e-22
gi|7705963 RAB9B, member RAS oncogene family [Homo sapiens]           100   1e-21
gi|10880989 RAB18, member RAS oncogene family [Homo sapiens]          100   2e-21
gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens]          100   2e-21
gi|82659107 ras-related GTP-binding protein 4b [Homo sapiens]          99   2e-21
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap...    99   3e-21
gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]         99   3e-21
gi|34485711 Ras-related protein Rab-27A [Homo sapiens]                 99   4e-21
gi|34485709 Ras-related protein Rab-27A [Homo sapiens]                 99   4e-21
gi|34485706 Ras-related protein Rab-27A [Homo sapiens]                 99   4e-21
gi|19923264 Ras-related protein Rab-27A [Homo sapiens]                 99   4e-21

>gi|5453555 ras-related nuclear protein [Homo sapiens]
          Length = 216

 Score =  446 bits (1147), Expect = e-126
 Identities = 216/216 (100%), Positives = 216/216 (100%)

Query: 1   MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK 60
           MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
Sbjct: 1   MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK 60

Query: 61  FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC 120
           FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
Sbjct: 61  FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC 120

Query: 121 GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP 180
           GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
Sbjct: 121 GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP 180

Query: 181 ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL 216
           ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
Sbjct: 181 ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL 216


>gi|34147513 RAB7, member RAS oncogene family [Homo sapiens]
          Length = 207

 Score =  110 bits (274), Expect = 1e-24
 Identities = 55/169 (32%), Positives = 96/169 (56%), Gaps = 7/169 (4%)

Query: 8   QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTA 67
           +V  K++++GD G GKT+ + +++  +F  +Y AT+G +        +   +   +WDTA
Sbjct: 6   KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 65

Query: 68  GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGN 122
           GQE+F  L   +Y  A C +++FDVT+  T+K + +W  + +     R  EN P V+ GN
Sbjct: 66  GQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGN 125

Query: 123 KVDIKDRKVKAK--SIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           K+D+++R+V  K      + K N+ Y++ SAK   N E+ F  +AR  +
Sbjct: 126 KIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNAL 174


>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score =  109 bits (273), Expect = 2e-24
 Identities = 58/164 (35%), Positives = 93/164 (56%), Gaps = 3/164 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FK+VL+G+ G GKT  V+R   G F     AT+GV+        N   +K  +WDTAGQE
Sbjct: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN-IPIVLCGNKVDIKDR 129
           +F  +   YY  A   I+ +D+T   +++ +P W R++ +   N +  VL GNK+D+ +R
Sbjct: 70  RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAER 129

Query: 130 K--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGD 171
           +   + ++  F   +++ Y + SAK + N EK FL LA +LI +
Sbjct: 130 REVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISE 173


>gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]
          Length = 200

 Score =  107 bits (268), Expect = 6e-24
 Identities = 58/175 (33%), Positives = 98/175 (56%), Gaps = 8/175 (4%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+L+GD G GKT  + R     F   +++T+G++            IK  +WDTAGQE
Sbjct: 10  FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQE 69

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNKVDIKDR 129
           +F  +   YY  A   ++++D+T+  +++N+  W R++     E++  +L GNK D+ D+
Sbjct: 70  RFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDK 129

Query: 130 KV--KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL-----IGDPNLEFV 177
           +V  K K     R+  +++++ SAK+N N EK FL LA  +     + +PN E V
Sbjct: 130 RVVPKGKGGQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENV 184


>gi|34485714 Ras-related protein Rab-23 [Homo sapiens]
          Length = 237

 Score =  104 bits (259), Expect = 7e-23
 Identities = 53/166 (31%), Positives = 93/166 (56%), Gaps = 6/166 (3%)

Query: 8   QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTA 67
           +V  K+V+VG+G  GK++ ++R+  G F K Y  T+GV+        N   ++  +WDTA
Sbjct: 7   EVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTA 66

Query: 68  GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIK 127
           GQE+F  +   YY  AQ  +++F  T R +++ V +W   +V    +IP VL  NK+D+ 
Sbjct: 67  GQEEFDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVGDIPTVLVQNKIDLL 126

Query: 128 D----RKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           D    +  +A+++   ++  L++Y  S K + N  + F +LA K +
Sbjct: 127 DDSCIKNEEAEALA--KRLKLRFYRTSVKEDLNVNEVFKYLAEKYL 170


>gi|50234889 RAB43 protein [Homo sapiens]
          Length = 212

 Score =  104 bits (259), Expect = 7e-23
 Identities = 66/180 (36%), Positives = 97/180 (53%), Gaps = 22/180 (12%)

Query: 5   GEPQVQ----FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK 60
           G+P  Q    FKLVLVGD   GKT  V+R  TG F ++  +T+GV+            +K
Sbjct: 9   GDPDEQYDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVK 68

Query: 61  FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIVL 119
             +WDTAGQE+F  +   YY  A  AI+ +D+T R ++ +VP+W  D+ +    NI  +L
Sbjct: 69  LQIWDTAGQERFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLL 128

Query: 120 CGNKVDIKDRK----VKAKSIVFHRKKNLQYYDI------SAKSNYNFEKPFLWLARKLI 169
            GNK D+ + +     +A+S+  H       YDI      SAK + N E+ FL +A +LI
Sbjct: 129 IGNKSDLSELREVSLAEAQSLAEH-------YDILCAIETSAKDSSNVEEAFLRVATELI 181


>gi|34485716 Ras-related protein Rab-23 [Homo sapiens]
          Length = 237

 Score =  104 bits (259), Expect = 7e-23
 Identities = 53/166 (31%), Positives = 93/166 (56%), Gaps = 6/166 (3%)

Query: 8   QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTA 67
           +V  K+V+VG+G  GK++ ++R+  G F K Y  T+GV+        N   ++  +WDTA
Sbjct: 7   EVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTA 66

Query: 68  GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIK 127
           GQE+F  +   YY  AQ  +++F  T R +++ V +W   +V    +IP VL  NK+D+ 
Sbjct: 67  GQEEFDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVGDIPTVLVQNKIDLL 126

Query: 128 D----RKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           D    +  +A+++   ++  L++Y  S K + N  + F +LA K +
Sbjct: 127 DDSCIKNEEAEALA--KRLKLRFYRTSVKEDLNVNEVFKYLAEKYL 170


>gi|19923260 RAB4A, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score =  103 bits (258), Expect = 9e-23
 Identities = 56/162 (34%), Positives = 95/162 (58%), Gaps = 3/162 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FK +++G+ GTGK+  + + +  +F+     T+GVE    + +     +K  +WDTAGQE
Sbjct: 14  FKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQE 73

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNKVDI-KD 128
           +F  +   YY  A  A++++D+TSR TY  + NW  D  +   +NI I+LCGNK D+  D
Sbjct: 74  RFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDAD 133

Query: 129 RKVK-AKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           R+V   ++  F ++  L + + SA +  N E+ F+  ARK++
Sbjct: 134 REVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKIL 175


>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score =  103 bits (258), Expect = 9e-23
 Identities = 52/153 (33%), Positives = 84/153 (54%), Gaps = 2/153 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+++GD G GK++ + R     F   Y+ T+GV+        N   +K  +WDTAGQE
Sbjct: 9   FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQE 68

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRK 130
           +F  +   YY      I+++DVTS  ++ NV  W  ++ + C+++  +L GNK D  +RK
Sbjct: 69  RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERK 128

Query: 131 V--KAKSIVFHRKKNLQYYDISAKSNYNFEKPF 161
           V     +  F  +  +Q ++ SAK N N E+ F
Sbjct: 129 VVETEDAYKFAGQMGIQLFETSAKENVNVEEMF 161


>gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo
           sapiens]
          Length = 216

 Score =  103 bits (256), Expect = 1e-22
 Identities = 57/169 (33%), Positives = 93/169 (55%), Gaps = 3/169 (1%)

Query: 3   AQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFN 62
           A G    QFKLVL+G+   GK++ V R + G+F +   +T+G          +   +KF 
Sbjct: 14  AAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFE 73

Query: 63  VWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCG 121
           +WDTAGQE++  L   YY  AQ AI+++D+T+  T+    NW ++L R    NI I L G
Sbjct: 74  IWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAG 133

Query: 122 NKVDIKDRKVK--AKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
           NK D+  ++     ++  +    +L + + SAK+  N  + F+ +A+KL
Sbjct: 134 NKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 182


>gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo
           sapiens]
          Length = 216

 Score =  103 bits (256), Expect = 1e-22
 Identities = 57/169 (33%), Positives = 93/169 (55%), Gaps = 3/169 (1%)

Query: 3   AQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFN 62
           A G    QFKLVL+G+   GK++ V R + G+F +   +T+G          +   +KF 
Sbjct: 14  AAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFE 73

Query: 63  VWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCG 121
           +WDTAGQE++  L   YY  AQ AI+++D+T+  T+    NW ++L R    NI I L G
Sbjct: 74  IWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAG 133

Query: 122 NKVDIKDRKVK--AKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
           NK D+  ++     ++  +    +L + + SAK+  N  + F+ +A+KL
Sbjct: 134 NKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 182


>gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]
          Length = 217

 Score =  102 bits (254), Expect = 2e-22
 Identities = 59/190 (31%), Positives = 100/190 (52%), Gaps = 4/190 (2%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FK++L+GD   GKT  V+   +G + +    T+GV+        +   +K  VWDTAGQE
Sbjct: 18  FKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQVWDTAGQE 77

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV-CENIPIVLCGNKVDIKDR 129
           +F  +   YY  A  AII +D+T R T++++P+W  ++ +    N+ I+L GNK D+ ++
Sbjct: 78  RFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIGNKCDLWEK 137

Query: 130 K---VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPE 186
           +    +    +  +   L   + SAK + N E+ F+ +A++LI   +L      AL    
Sbjct: 138 RHVLFEDACTLAEKYGLLAVLETSAKESKNIEEVFVLMAKELIARNSLHLYGESALNGLP 197

Query: 187 VVMDPALAAQ 196
           +   P L AQ
Sbjct: 198 LDSSPVLMAQ 207


>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
           family [Homo sapiens]
          Length = 327

 Score =  102 bits (254), Expect = 2e-22
 Identities = 54/162 (33%), Positives = 91/162 (56%), Gaps = 3/162 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+L+GD G GKT  + R     F   Y++T+G++            IK  VWDTAGQE
Sbjct: 133 FKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQE 192

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-RVCENIPIVLCGNKVDIK-D 128
           +F  +   YY  A   I+ +D+T   +++N+ NW + ++      +  +L GNK D++  
Sbjct: 193 RFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKCDMEAK 252

Query: 129 RKV-KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           RKV K ++    R+  +++++ SAKS+ N ++ F  LAR ++
Sbjct: 253 RKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 294


>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score =  102 bits (254), Expect = 2e-22
 Identities = 54/162 (33%), Positives = 91/162 (56%), Gaps = 3/162 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+L+GD G GKT  + R     F   Y++T+G++            IK  VWDTAGQE
Sbjct: 133 FKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQE 192

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-RVCENIPIVLCGNKVDIK-D 128
           +F  +   YY  A   I+ +D+T   +++N+ NW + ++      +  +L GNK D++  
Sbjct: 193 RFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKCDMEAK 252

Query: 129 RKV-KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           RKV K ++    R+  +++++ SAKS+ N ++ F  LAR ++
Sbjct: 253 RKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 294


>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score =  102 bits (254), Expect = 2e-22
 Identities = 54/162 (33%), Positives = 91/162 (56%), Gaps = 3/162 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+L+GD G GKT  + R     F   Y++T+G++            IK  VWDTAGQE
Sbjct: 133 FKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQE 192

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-RVCENIPIVLCGNKVDIK-D 128
           +F  +   YY  A   I+ +D+T   +++N+ NW + ++      +  +L GNK D++  
Sbjct: 193 RFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKCDMEAK 252

Query: 129 RKV-KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           RKV K ++    R+  +++++ SAKS+ N ++ F  LAR ++
Sbjct: 253 RKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 294


>gi|4759012 RAB9A, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score =  102 bits (253), Expect = 3e-22
 Identities = 52/166 (31%), Positives = 91/166 (54%), Gaps = 7/166 (4%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FK++L+GDGG GK++ + R++T +F+ +   T+GVE        +   +   +WDTAGQE
Sbjct: 8   FKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQE 67

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-----VRVCENIPIVLCGNKVD 125
           +F  LR  +Y  + C ++ F V    +++N+ NW ++      V+  E+ P V+ GNK+D
Sbjct: 68  RFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKID 127

Query: 126 IKDRKVKAKSIVFHRKKN--LQYYDISAKSNYNFEKPFLWLARKLI 169
           I +R+V  +      + N    Y++ SAK   N    F    R+++
Sbjct: 128 ISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVL 173


>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score =  102 bits (253), Expect = 3e-22
 Identities = 54/162 (33%), Positives = 91/162 (56%), Gaps = 3/162 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+L+GD G GKT  + R     F   Y++T+G++            IK  VWDTAGQE
Sbjct: 9   FKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQE 68

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNKVDIK-D 128
           +F  +   YY  A   I+++D+T   +++N+ NW + +       +  +L GNK D++  
Sbjct: 69  RFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAK 128

Query: 129 RKV-KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           RKV K ++    R+  +++++ SAKS+ N ++ F  LAR ++
Sbjct: 129 RKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 170


>gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens]
          Length = 215

 Score =  101 bits (252), Expect = 4e-22
 Identities = 57/169 (33%), Positives = 96/169 (56%), Gaps = 7/169 (4%)

Query: 5   GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVW 64
           G    QFKLVL+G+   GK++ V R + G+F +   +T+G          +   +KF +W
Sbjct: 15  GNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIW 74

Query: 65  DTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCGNK 123
           DTAGQE++  L   YY  AQ AI+++D+T+  ++    NW ++L R    NI I L GNK
Sbjct: 75  DTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNK 134

Query: 124 VDIKDRKV----KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
            D+ +++     +A+S  +    +L + + SAK++ N  + F+ +A+KL
Sbjct: 135 ADLANKRAVDFQEAQS--YADDNSLLFMETSAKTSMNVNEIFMAIAKKL 181


>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score =  100 bits (249), Expect = 9e-22
 Identities = 53/161 (32%), Positives = 89/161 (55%), Gaps = 3/161 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+L+GD G GK+  + R     + + Y++T+GV+        +   IK  +WDTAGQE
Sbjct: 9   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCGNKVDIKDR 129
           +F  +   YY  A   I+++DVT + +Y NV  W +++ R   EN+  +L GNK D+  +
Sbjct: 69  RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTK 128

Query: 130 KVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
           KV   +    F     + + + SAK+  N E+ F+ +A ++
Sbjct: 129 KVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEI 169


>gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens]
          Length = 215

 Score =  100 bits (249), Expect = 9e-22
 Identities = 57/171 (33%), Positives = 96/171 (56%), Gaps = 7/171 (4%)

Query: 5   GEPQV----QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK 60
           G+PQ     QFKLVL+G+   GK++ V R + G+F +   +T+G          +   +K
Sbjct: 11  GQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVK 70

Query: 61  FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVL 119
           F +WDTAGQE++  L   YY  AQ AI+++D+T++ T+     W ++L R    +I I L
Sbjct: 71  FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIAL 130

Query: 120 CGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
            GNK D+ ++++    ++  +    +L + + SAK+  N    FL +A+KL
Sbjct: 131 AGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKL 181


>gi|7705963 RAB9B, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score =  100 bits (248), Expect = 1e-21
 Identities = 54/165 (32%), Positives = 91/165 (55%), Gaps = 7/165 (4%)

Query: 12  KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
           K++L+GDGG GK++ + R++T +F+ +   T+GVE        +   +   +WDTAGQE+
Sbjct: 9   KVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQER 68

Query: 72  FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-----VRVCENIPIVLCGNKVDI 126
           F  LR  +Y  A C ++ F V  R +++N+ NW ++      V+  E+ P V+ GNKVD 
Sbjct: 69  FKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPEHFPFVVLGNKVDK 128

Query: 127 KDRKVKAKSIVFHRKKN--LQYYDISAKSNYNFEKPFLWLARKLI 169
           +DR+V  +       +N    Y + SAK + N    F    R+++
Sbjct: 129 EDRQVTTEEAQTWCMENGDYPYLETSAKDDTNVTVAFEEAVRQVL 173


>gi|10880989 RAB18, member RAS oncogene family [Homo sapiens]
          Length = 206

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 56/166 (33%), Positives = 91/166 (54%), Gaps = 3/166 (1%)

Query: 12  KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
           K++++G+ G GK++ + R     F+ +  AT+GV+        +    K  +WDTAGQE+
Sbjct: 10  KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQER 69

Query: 72  FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIV--LCGNKVDIKDR 129
           F  L   YY  AQ  I+++DVT R T+  + NW  +L   C    IV  L GNK+D ++R
Sbjct: 70  FRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENR 129

Query: 130 KV-KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNL 174
           +V + + + F RK ++ + + SAK+    +  F  L  K+I  P L
Sbjct: 130 EVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGL 175


>gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 14/169 (8%)

Query: 5   GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPL-VFHTNRGP----- 58
           G+     KL+ +GD G GKTTF+ R+   +F  K++ T+G++     V +  +GP     
Sbjct: 4   GDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSG 63

Query: 59  ----IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV--RVC 112
               +   +WDTAGQE+F  L   ++  A   ++MFD+TS+ ++ NV NW   L     C
Sbjct: 64  KAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYC 123

Query: 113 ENIPIVLCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEK 159
           EN  IVL GNK D+ D++   + ++     K  + Y++ SA +  N EK
Sbjct: 124 ENPDIVLIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNVEK 172


>gi|82659107 ras-related GTP-binding protein 4b [Homo sapiens]
          Length = 213

 Score = 99.4 bits (246), Expect = 2e-21
 Identities = 54/162 (33%), Positives = 93/162 (57%), Gaps = 3/162 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FK +++G  GTGK+  + + +  +F++    T+GVE    V +     +K  +WDTAGQE
Sbjct: 9   FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQE 68

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPIVLCGNKVDI-KD 128
           +F  +   YY  A  A++++D+TSR TY ++  W  D   +   NI ++LCGNK D+  +
Sbjct: 69  RFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPE 128

Query: 129 RKVK-AKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           R+V   ++  F ++  L + + SA +  N E+ FL  AR ++
Sbjct: 129 REVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTIL 170


>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
           sapiens]
          Length = 205

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 52/161 (32%), Positives = 89/161 (55%), Gaps = 3/161 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FKL+L+GD G GK+  + R     + + Y++T+GV+        +   IK  +WDTAGQE
Sbjct: 12  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCGNKVDIKDR 129
           +F  +   YY  A   I+++DVT + ++ NV  W +++ R   EN+  +L GNK D+  +
Sbjct: 72  RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK 131

Query: 130 KVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
           KV   +    F     + + + SAK+  N E+ F+ +A ++
Sbjct: 132 KVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172


>gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 53/154 (34%), Positives = 84/154 (54%), Gaps = 3/154 (1%)

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
           FK+VL+GD G GK+  + R    EF  +  +T+GVE        +   IK  +WDTAGQE
Sbjct: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNKVDIKDR 129
           ++  +   YY  A  A++++D+   +TY+NV  W ++L      NI I+L GNK D++  
Sbjct: 72  RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHL 131

Query: 130 KV--KAKSIVFHRKKNLQYYDISAKSNYNFEKPF 161
           +     ++  F  K NL + + SA  + N E+ F
Sbjct: 132 RAVPTDEARAFAEKNNLSFIETSALDSTNVEEAF 165


>gi|34485711 Ras-related protein Rab-27A [Homo sapiens]
          Length = 221

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 54/171 (31%), Positives = 92/171 (53%), Gaps = 14/171 (8%)

Query: 3   AQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPL-VFHTNRGP--- 58
           + G+     K + +GD G GKT+ + ++  G+F  K++ T+G++     V +   GP   
Sbjct: 2   SDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGA 61

Query: 59  ------IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV--R 110
                 I   +WDTAGQE+F  L   ++  A   +++FD+T+  ++ NV NW   L    
Sbjct: 62  TGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHA 121

Query: 111 VCENIPIVLCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEK 159
            CEN  IVLCGNK D++D++V  + ++I    K  + Y++ SA +  N  +
Sbjct: 122 YCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQ 172


>gi|34485709 Ras-related protein Rab-27A [Homo sapiens]
          Length = 221

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 54/171 (31%), Positives = 92/171 (53%), Gaps = 14/171 (8%)

Query: 3   AQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPL-VFHTNRGP--- 58
           + G+     K + +GD G GKT+ + ++  G+F  K++ T+G++     V +   GP   
Sbjct: 2   SDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGA 61

Query: 59  ------IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV--R 110
                 I   +WDTAGQE+F  L   ++  A   +++FD+T+  ++ NV NW   L    
Sbjct: 62  TGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHA 121

Query: 111 VCENIPIVLCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEK 159
            CEN  IVLCGNK D++D++V  + ++I    K  + Y++ SA +  N  +
Sbjct: 122 YCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQ 172


>gi|34485706 Ras-related protein Rab-27A [Homo sapiens]
          Length = 221

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 54/171 (31%), Positives = 92/171 (53%), Gaps = 14/171 (8%)

Query: 3   AQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPL-VFHTNRGP--- 58
           + G+     K + +GD G GKT+ + ++  G+F  K++ T+G++     V +   GP   
Sbjct: 2   SDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGA 61

Query: 59  ------IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV--R 110
                 I   +WDTAGQE+F  L   ++  A   +++FD+T+  ++ NV NW   L    
Sbjct: 62  TGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHA 121

Query: 111 VCENIPIVLCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEK 159
            CEN  IVLCGNK D++D++V  + ++I    K  + Y++ SA +  N  +
Sbjct: 122 YCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQ 172


>gi|19923264 Ras-related protein Rab-27A [Homo sapiens]
          Length = 221

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 54/171 (31%), Positives = 92/171 (53%), Gaps = 14/171 (8%)

Query: 3   AQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPL-VFHTNRGP--- 58
           + G+     K + +GD G GKT+ + ++  G+F  K++ T+G++     V +   GP   
Sbjct: 2   SDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGA 61

Query: 59  ------IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV--R 110
                 I   +WDTAGQE+F  L   ++  A   +++FD+T+  ++ NV NW   L    
Sbjct: 62  TGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHA 121

Query: 111 VCENIPIVLCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEK 159
            CEN  IVLCGNK D++D++V  + ++I    K  + Y++ SA +  N  +
Sbjct: 122 YCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQ 172


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,438,576
Number of Sequences: 37866
Number of extensions: 356060
Number of successful extensions: 1234
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 823
Number of HSP's gapped (non-prelim): 232
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.