Guide to the Human Genome
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Search of human proteins with 53831989

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53831989 tweety 1 isoform 2 [Homo sapiens]
         (460 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|53831989 tweety 1 isoform 2 [Homo sapiens]                         916   0.0  
gi|10257437 tweety 1 isoform 1 [Homo sapiens]                         836   0.0  
gi|53988385 tweety 2 isoform 1 [Homo sapiens]                         340   1e-93
gi|51100978 tweety 3 [Homo sapiens]                                   306   2e-83
gi|53988387 tweety 2 isoform 2 [Homo sapiens]                          99   8e-21
gi|56237021 fibrillin 3 precursor [Homo sapiens]                       33   0.71 
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]                     32   1.6  
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]                      32   1.6  
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]           31   2.7  
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]            31   2.7  
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]           31   2.7  
gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]           31   2.7  
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        31   2.7  
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        31   2.7  
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         31   2.7  
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         31   2.7  
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         31   2.7  
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         31   2.7  
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         31   2.7  
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         31   2.7  
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]        31   2.7  
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]        31   2.7  
gi|194306623 immunoglobulin superfamily containing leucine-rich ...    31   2.7  
gi|194306621 immunoglobulin superfamily containing leucine-rich ...    31   2.7  
gi|39930401 immunoglobulin superfamily containing leucine-rich r...    31   2.7  
gi|194306618 immunoglobulin superfamily containing leucine-rich ...    31   2.7  
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]        30   6.0  
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]        30   6.0  
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]          30   6.0  
gi|181337167 solute carrier family 7 (cationic amino acid transp...    30   6.0  

>gi|53831989 tweety 1 isoform 2 [Homo sapiens]
          Length = 460

 Score =  916 bits (2367), Expect = 0.0
 Identities = 460/460 (100%), Positives = 460/460 (100%)

Query: 1   MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLI 60
           MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLI
Sbjct: 1   MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLI 60

Query: 61  FIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVS 120
           FIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVS
Sbjct: 61  FIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVS 120

Query: 121 QLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAE 180
           QLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAE
Sbjct: 121 QLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAE 180

Query: 181 AAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSK 240
           AAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSK
Sbjct: 181 AAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSK 240

Query: 241 WLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYY 300
           WLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYY
Sbjct: 241 WLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYY 300

Query: 301 LLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGN 360
           LLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGN
Sbjct: 301 LLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGN 360

Query: 361 FHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALF 420
           FHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALF
Sbjct: 361 FHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALF 420

Query: 421 PPRNPSALCSGSRLSEPLLPAGLEPGSPLRSFPGCRRRPH 460
           PPRNPSALCSGSRLSEPLLPAGLEPGSPLRSFPGCRRRPH
Sbjct: 421 PPRNPSALCSGSRLSEPLLPAGLEPGSPLRSFPGCRRRPH 460


>gi|10257437 tweety 1 isoform 1 [Homo sapiens]
          Length = 450

 Score =  836 bits (2160), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLI 60
           MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLI
Sbjct: 1   MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLI 60

Query: 61  FIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVS 120
           FIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVS
Sbjct: 61  FIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVS 120

Query: 121 QLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAE 180
           QLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAE
Sbjct: 121 QLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAE 180

Query: 181 AAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSK 240
           AAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSK
Sbjct: 181 AAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSK 240

Query: 241 WLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYY 300
           WLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYY
Sbjct: 241 WLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYY 300

Query: 301 LLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGN 360
           LLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGN
Sbjct: 301 LLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGN 360

Query: 361 FHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALF 420
           FHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALF
Sbjct: 361 FHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALF 420

Query: 421 PP 422
           PP
Sbjct: 421 PP 422


>gi|53988385 tweety 2 isoform 1 [Homo sapiens]
          Length = 534

 Score =  340 bits (873), Expect = 1e-93
 Identities = 174/413 (42%), Positives = 260/413 (62%), Gaps = 4/413 (0%)

Query: 12  WVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCC 71
           WV  LH +P    +L+PV S F+P ++ YQ++LL +  +A + LGL+LIF+  YL+  C 
Sbjct: 13  WVVWLHSVPHVGLRLQPVNSTFSPGDESYQESLLFLGLVAAVCLGLNLIFLVAYLVCACH 72

Query: 72  CRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANH 131
           CR  +   +K       C+TW+ +VA L  C  +G+GFYGNSET+DG  QL  +L  ANH
Sbjct: 73  CRRDDAVQTK--QHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQLMYSLDDANH 130

Query: 132 TLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAF 191
           T S ID LV  T +++   +   L  L E+   R + +   +  ++ A +   QL GL  
Sbjct: 131 TFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGSVVVQLSGLPV 190

Query: 192 WQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSL 251
           W+ V +   ++++   +VE YRWL+Y+LL +L+L++CL   LGLAK+SK L+  M     
Sbjct: 191 WREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKCLLASMLCCGA 250

Query: 252 LVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPF 311
           L L+LSW S+  + + AV  SDFC  PD ++LN+T+ +  +S+++  YYL C+++ S+PF
Sbjct: 251 LSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQ--ISTEVTRYYLYCSQSGSSPF 308

Query: 312 QQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCR 371
           QQ LT  QRAL  +  Q+ GL + AVP F +A++ LL+++  LN +E + HQL A++ CR
Sbjct: 309 QQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCR 368

Query: 372 SLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPRN 424
            LHKDY  AL G+C D L+GLL+L LFS L+A A +T +C+ PRAW  F  RN
Sbjct: 369 GLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRN 421


>gi|51100978 tweety 3 [Homo sapiens]
          Length = 523

 Score =  306 bits (785), Expect = 2e-83
 Identities = 163/411 (39%), Positives = 232/411 (56%), Gaps = 3/411 (0%)

Query: 7   YRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYL 66
           Y    WV LLH+LP  D       S F P++ +YQQALLL+ A A   L L L+F+  Y 
Sbjct: 6   YAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLFLLFYS 65

Query: 67  IRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSAL 126
              CC R               C  W  I+A L    GI +GFYGN ETSDG+ + + +L
Sbjct: 66  FWLCCRRRKSEEHLDADCC---CTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSL 122

Query: 127 LHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQL 186
            HAN T++ +   V +T   L       L TLE  L  R E + A +  +   E      
Sbjct: 123 RHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYT 182

Query: 187 QGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVM 246
             + FW+   +S   +AE V   + YRWL Y+ LLLL++++CL  L+GL + SK +++ +
Sbjct: 183 AAIPFWRNTAVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGV 242

Query: 247 TVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRA 306
            ++ +L LV+SWG++GLE A +VG SDFC +PD YV  + +E + LS DIL YYL C+  
Sbjct: 243 CLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPR 302

Query: 307 VSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVA 366
            +NPFQQ+L+ S +AL  +   +  L R    + P+ + PLL ++E LN TE N   L A
Sbjct: 303 AANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTA 362

Query: 367 LLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAW 417
           L+ CRSLH DY  AL G C D +EGL++L LFS ++A   ++ +CS+P  W
Sbjct: 363 LVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTW 413


>gi|53988387 tweety 2 isoform 2 [Homo sapiens]
          Length = 213

 Score = 99.0 bits (245), Expect = 8e-21
 Identities = 49/97 (50%), Positives = 68/97 (70%)

Query: 328 QLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCED 387
           Q+ GL + AVP F +A++ LL+++  LN +E + HQL A++ CR LHKDY  AL G+C D
Sbjct: 4   QVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYD 63

Query: 388 ALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPRN 424
            L+GLL+L LFS L+A A +T +C+ PRAW  F  RN
Sbjct: 64  GLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRN 100


>gi|56237021 fibrillin 3 precursor [Homo sapiens]
          Length = 2809

 Score = 32.7 bits (73), Expect = 0.71
 Identities = 32/102 (31%), Positives = 37/102 (36%), Gaps = 14/102 (13%)

Query: 359 GNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALA------TALCS 412
           G+   +V   HCR       +     CED   G  F +LF    AG LA         C 
Sbjct: 261 GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCD 320

Query: 413 LPRAWA------LFPPRNPSALCSGSRLSEPLLPA--GLEPG 446
             R WA      L PPR  +          PLLP   GL PG
Sbjct: 321 RGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPG 362


>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
          Length = 1059

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 6/44 (13%)

Query: 51  AGLG---LGLSLIFIAVYLIRFCCCRPPEPPG---SKIPSPGGG 88
           AG+G   LG+ L+ +A  L+  CCC+  +P G      P P GG
Sbjct: 631 AGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGG 674


>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
          Length = 1040

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 6/44 (13%)

Query: 51  AGLG---LGLSLIFIAVYLIRFCCCRPPEPPG---SKIPSPGGG 88
           AG+G   LG+ L+ +A  L+  CCC+  +P G      P P GG
Sbjct: 631 AGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGG 674


>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
          Length = 541

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 6/77 (7%)

Query: 119 VSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTL------EEVLEPRTELVAAA 172
           +  LSS L  AN T+   +  +     R+ + V T +T L      EE L    +L+ A 
Sbjct: 206 IQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEAL 265

Query: 173 RGARRQAEAAAQQLQGL 189
           +  +R+ +AA Q  + L
Sbjct: 266 QEEKRELKAALQSQENL 282


>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
          Length = 703

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 6/77 (7%)

Query: 119 VSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTL------EEVLEPRTELVAAA 172
           +  LSS L  AN T+   +  +     R+ + V T +T L      EE L    +L+ A 
Sbjct: 206 IQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEAL 265

Query: 173 RGARRQAEAAAQQLQGL 189
           +  +R+ +AA Q  + L
Sbjct: 266 QEEKRELKAALQSQENL 282


>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
          Length = 475

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 6/77 (7%)

Query: 119 VSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTL------EEVLEPRTELVAAA 172
           +  LSS L  AN T+   +  +     R+ + V T +T L      EE L    +L+ A 
Sbjct: 206 IQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEAL 265

Query: 173 RGARRQAEAAAQQLQGL 189
           +  +R+ +AA Q  + L
Sbjct: 266 QEEKRELKAALQSQENL 282


>gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]
          Length = 495

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 6/77 (7%)

Query: 119 VSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTL------EEVLEPRTELVAAA 172
           +  LSS L  AN T+   +  +     R+ + V T +T L      EE L    +L+ A 
Sbjct: 206 IQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEAL 265

Query: 173 RGARRQAEAAAQQLQGL 189
           +  +R+ +AA Q  + L
Sbjct: 266 QEEKRELKAALQSQENL 282


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1394


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1348 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1398


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1394


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1312 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1362


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1481 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1531


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1322 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1372


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1330 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1380


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 141  LETVERLGEAVRTE----LTTLEEVLEPRTELVAAARGARRQAEAAAQQLQ 187
            +E  ERL E  R E    L  +E  LE + +L  A   A+ QAE  A++LQ
Sbjct: 1371 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1421


>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
          Length = 449

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 21/125 (16%)

Query: 178 QAEAAAQQLQGLAF-WQGVPLSPLQVAENVSF----VEEYRWLAYVLLLL-LELLVCLFT 231
           Q E+    +  L F WQ    +P+QVAE ++     ++E + L Y           C+  
Sbjct: 188 QLESFGYTMNDLIFEWQDE--APVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEV 245

Query: 232 LLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLE-----AATAVGLSDFCSNPDPYVLNLT 286
              L +Q  + +I M + SLL+++LSW S  +      A  A+G++         VL +T
Sbjct: 246 RFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITT--------VLTMT 297

Query: 287 QEETG 291
            + +G
Sbjct: 298 TQSSG 302


>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
          Length = 464

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 21/125 (16%)

Query: 178 QAEAAAQQLQGLAF-WQGVPLSPLQVAENVSF----VEEYRWLAYVLLLL-LELLVCLFT 231
           Q E+    +  L F WQ    +P+QVAE ++     ++E + L Y           C+  
Sbjct: 188 QLESFGYTMNDLIFEWQDE--APVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEV 245

Query: 232 LLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLE-----AATAVGLSDFCSNPDPYVLNLT 286
              L +Q  + +I M + SLL+++LSW S  +      A  A+G++         VL +T
Sbjct: 246 RFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITT--------VLTMT 297

Query: 287 QEETG 291
            + +G
Sbjct: 298 TQSSG 302


>gi|194306623 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 20/152 (13%)

Query: 308 SNPFQQRLTLSQRALANI-HSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVA 366
           S P+     LS   L  + H++L  L R+A+   P  +   ++      +  G F  L A
Sbjct: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSA 172

Query: 367 LLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALA---TALCSLPRAWALFP-- 421
           L H +  H  +             GL++L  ++  +  +L    +  C+ P A    P  
Sbjct: 173 LSHLQLYHNPFHCGC---------GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVY 223

Query: 422 --PRNPSALCSGSRLSEPLLPAGLEPGSPLRS 451
             P  P A  S    +EP L A   PG+PLR+
Sbjct: 224 RLPALPCAPPSVHLSAEPPLEA---PGTPLRA 252


>gi|194306621 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 20/152 (13%)

Query: 308 SNPFQQRLTLSQRALANI-HSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVA 366
           S P+     LS   L  + H++L  L R+A+   P  +   ++      +  G F  L A
Sbjct: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSA 172

Query: 367 LLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALA---TALCSLPRAWALFP-- 421
           L H +  H  +             GL++L  ++  +  +L    +  C+ P A    P  
Sbjct: 173 LSHLQLYHNPFHCGC---------GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVY 223

Query: 422 --PRNPSALCSGSRLSEPLLPAGLEPGSPLRS 451
             P  P A  S    +EP L A   PG+PLR+
Sbjct: 224 RLPALPCAPPSVHLSAEPPLEA---PGTPLRA 252


>gi|39930401 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 20/152 (13%)

Query: 308 SNPFQQRLTLSQRALANI-HSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVA 366
           S P+     LS   L  + H++L  L R+A+   P  +   ++      +  G F  L A
Sbjct: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSA 172

Query: 367 LLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALA---TALCSLPRAWALFP-- 421
           L H +  H  +             GL++L  ++  +  +L    +  C+ P A    P  
Sbjct: 173 LSHLQLYHNPFHCGC---------GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVY 223

Query: 422 --PRNPSALCSGSRLSEPLLPAGLEPGSPLRS 451
             P  P A  S    +EP L A   PG+PLR+
Sbjct: 224 RLPALPCAPPSVHLSAEPPLEA---PGTPLRA 252


>gi|194306618 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 20/152 (13%)

Query: 308 SNPFQQRLTLSQRALANI-HSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVA 366
           S P+     LS   L  + H++L  L R+A+   P  +   ++      +  G F  L A
Sbjct: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSA 172

Query: 367 LLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALA---TALCSLPRAWALFP-- 421
           L H +  H  +             GL++L  ++  +  +L    +  C+ P A    P  
Sbjct: 173 LSHLQLYHNPFHCGC---------GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVY 223

Query: 422 --PRNPSALCSGSRLSEPLLPAGLEPGSPLRS 451
             P  P A  S    +EP L A   PG+PLR+
Sbjct: 224 RLPALPCAPPSVHLSAEPPLEA---PGTPLRA 252


>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
          Length = 452

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 18/103 (17%)

Query: 199 PLQVAENVSF----VEEYRWLAYVLLLL-LELLVCLFTLLGLAKQSKWLVIVMTVMSLLV 253
           P+QVAE ++     ++E + L Y           C+     L +Q  + +I M + SLL+
Sbjct: 209 PVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268

Query: 254 LVLSWGSMGLE-----AATAVGLSDFCSNPDPYVLNLTQEETG 291
           ++LSW S  +      A  A+G++         VL +T + +G
Sbjct: 269 VILSWVSFWINMDAAPARVALGITT--------VLTMTTQSSG 303


>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 18/103 (17%)

Query: 199 PLQVAENVSF----VEEYRWLAYVLLLL-LELLVCLFTLLGLAKQSKWLVIVMTVMSLLV 253
           P+QVAE ++     ++E + L Y           C+     L +Q  + +I M + SLL+
Sbjct: 209 PVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268

Query: 254 LVLSWGSMGLE-----AATAVGLSDFCSNPDPYVLNLTQEETG 291
           ++LSW S  +      A  A+G++         VL +T + +G
Sbjct: 269 VILSWVSFWINMDAAPARVALGITT--------VLTMTTQSSG 303


>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 18/103 (17%)

Query: 199 PLQVAENVSF----VEEYRWLAYVLLLL-LELLVCLFTLLGLAKQSKWLVIVMTVMSLLV 253
           P+QVAE ++     ++E + L Y           C+     L +Q  + +I M + SLL+
Sbjct: 209 PVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268

Query: 254 LVLSWGSMGLE-----AATAVGLSDFCSNPDPYVLNLTQEETG 291
           ++LSW S  +      A  A+G++         VL +T + +G
Sbjct: 269 VILSWVSFWINMDAAPARVALGITT--------VLTMTTQSSG 303


>gi|181337167 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 14 [Homo sapiens]
          Length = 771

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 13/45 (28%), Positives = 27/45 (60%), Gaps = 3/45 (6%)

Query: 215 LAYVLLLLLELLVCLFTLLG---LAKQSKWLVIVMTVMSLLVLVL 256
           +  +LL +L  + C F + G   +++QS W ++++ +M LL+  L
Sbjct: 567 ICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTL 611


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,293,382
Number of Sequences: 37866
Number of extensions: 920525
Number of successful extensions: 3477
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3432
Number of HSP's gapped (non-prelim): 67
length of query: 460
length of database: 18,247,518
effective HSP length: 106
effective length of query: 354
effective length of database: 14,233,722
effective search space: 5038737588
effective search space used: 5038737588
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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