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Search of human proteins with 52485853
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
(1188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 2405 0.0
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 935 0.0
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 820 0.0
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 707 0.0
gi|62548866 integrin, alpha D precursor [Homo sapiens] 399 e-111
gi|34452173 integrin alpha X precursor [Homo sapiens] 399 e-110
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 392 e-108
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 380 e-105
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 380 e-105
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 328 2e-89
gi|148728188 integrin, alpha E precursor [Homo sapiens] 313 8e-85
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 250 6e-66
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 203 7e-52
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 189 1e-47
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 183 1e-45
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 181 3e-45
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 172 2e-42
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 172 2e-42
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 171 3e-42
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 171 3e-42
gi|49170034 integrin, alpha 8 [Homo sapiens] 167 7e-41
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 161 4e-39
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 158 3e-38
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 158 3e-38
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 156 1e-37
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 142 1e-33
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 98 4e-20
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 98 4e-20
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 94 6e-19
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 92 4e-18
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 2405 bits (6233), Expect = 0.0
Identities = 1188/1188 (100%), Positives = 1188/1188 (100%)
Query: 1 MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGA 60
MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGA
Sbjct: 1 MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGA 60
Query: 61 PLETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLA 120
PLETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLA
Sbjct: 61 PLETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLA 120
Query: 121 CSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVE 180
CSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVE
Sbjct: 121 CSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVE 180
Query: 181 VQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTET 240
VQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTET
Sbjct: 181 VQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTET 240
Query: 241 RTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVL 300
RTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVL
Sbjct: 241 RTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVL 300
Query: 301 GYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNET 360
GYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNET
Sbjct: 301 GYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNET 360
Query: 361 SFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN 420
SFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN
Sbjct: 361 SFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN 420
Query: 421 HGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYF 480
HGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYF
Sbjct: 421 HGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYF 480
Query: 481 GSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNA 540
GSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNA
Sbjct: 481 GSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNA 540
Query: 541 RFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATG 600
RFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATG
Sbjct: 541 RFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATG 600
Query: 601 LQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCK 660
LQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCK
Sbjct: 601 LQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCK 660
Query: 661 RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAV 720
RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAV
Sbjct: 661 RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAV 720
Query: 721 LLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNG 780
LLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNG
Sbjct: 721 LLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNG 780
Query: 781 CNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAV 840
CNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAV
Sbjct: 781 CNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAV 840
Query: 841 EATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFF 900
EATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFF
Sbjct: 841 EATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFF 900
Query: 901 RAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFT 960
RAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFT
Sbjct: 901 RAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFT 960
Query: 961 RSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL 1020
RSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL
Sbjct: 961 RSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL 1020
Query: 1021 KLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEI 1080
KLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEI
Sbjct: 1021 KLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEI 1080
Query: 1081 NFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQV 1140
NFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQV
Sbjct: 1081 NFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQV 1140
Query: 1141 PIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRREPGLDPTPKVLE 1188
PIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRREPGLDPTPKVLE
Sbjct: 1141 PIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRREPGLDPTPKVLE 1188
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 935 bits (2417), Expect = 0.0
Identities = 515/1180 (43%), Positives = 726/1180 (61%), Gaps = 41/1180 (3%)
Query: 1 MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGA 60
M+LP + L G FN+D PR+ PG A FGY+V QH G +W++VGA
Sbjct: 1 MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGA 60
Query: 61 PLETNGYQKTGDVYKCPV---IHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNS 117
P + + GDVY+CPV + C K +LG L N S NM LG+SL D
Sbjct: 61 PWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGG 120
Query: 118 FLACSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYP 177
F+AC+PLWS CGSS +++G+C+RV+++F+ ++AP QRC TYMD+VIVLDGSNSIYP
Sbjct: 121 FMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYP 180
Query: 178 WVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGG 237
W EVQ FL ++ K +I P QIQVG+VQYGE VHE+ L D+R+ ++VV AA ++ +R G
Sbjct: 181 WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREG 240
Query: 238 TETRTAFGIEFARSEAFQK--GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRY 295
ET+TA I A +E F + GGR A ++++V+TDGESHD +L ++ E VTRY
Sbjct: 241 RETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRY 300
Query: 296 AVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT 355
+AVLG+Y RR +P +FL EI+ IASDPD++ FFNVTDEAAL DIVDALGDRIF LEG+
Sbjct: 301 GIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGS 360
Query: 356 N-KNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEF 414
+ +NE+SFGLEMSQ GFS+H ++DG+L G VGAYDW G+VL ++ P R + EF
Sbjct: 361 HAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF 420
Query: 415 PEELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQ 474
P L+NH AYLGY+V+S++ R++++GAPRF H GKVI F + + ++ + Q+++G+
Sbjct: 421 PPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGE 480
Query: 475 QIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFN-EGRERGKVYVYEL-RQNLFVYNGTLK 532
QIGSYFGSE+ +D D DG TDVLLV APM+ + +E G+VYVY + +Q+L GTL+
Sbjct: 481 QIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQ 540
Query: 533 DSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRI 592
Q+ARFG ++ ++ DLNQD + DV VGAPLED H GA+Y++HG + + P QRI
Sbjct: 541 PEPP-QDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRI 599
Query: 593 TASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKI 652
A+ + L YFG S+ G+LDL+ D L+D+AVGA G A++L SRP+V + SL P I
Sbjct: 600 AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAI 659
Query: 653 NIFHRDCKRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGG 712
++ RDC+R G++A CL A LCF P +R+ A++DE RA D G
Sbjct: 660 SVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSG 719
Query: 713 DRFTNRAVLLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDH-GPMLDDGWPTTL 771
R + R + LS G CE+++FHVLDT+DY++PV +V ++L++ GP+L++G PT++
Sbjct: 720 QRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSI 779
Query: 772 RVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFII 831
+ VPF C D CV DLVL D+ R RK F++
Sbjct: 780 QKLVPFSKDCGPDNECVTDLVLQVNMDI--------RGSRK--------------APFVV 817
Query: 832 ESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQ 891
R++V V TLENR ENAY+T L++ S NL ASL + +S +EC +
Sbjct: 818 RGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPS--AHAR 875
Query: 892 VCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHL 951
+C+V +P F+ AKV F L+FEFS S L + ++L A SDS ER+ T +DN A ++
Sbjct: 876 LCSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYI 935
Query: 952 KYEADVLFTRSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPI 1011
+YE +LF+ S+L YEV P +L G GP F R+QNLG + + G+++ +P
Sbjct: 936 QYEPHLLFSSESTLHRYEVHPYGTLP--VGPGPEFKTTLRVQNLGCYVVSGLIISALLPA 993
Query: 1012 ATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE-EDLRRAPQLNHSNSDVVSINC 1070
GN L L +T+ N SC I N TE PV E+L+ +LN SN+ + C
Sbjct: 994 VAHGGNYFLSLSQVITN--NASC-IVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRC 1050
Query: 1071 NI-RLVPNQEINFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIV 1129
++ +L E++ LL + + K+KS+ ++ L + S E + +
Sbjct: 1051 HLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESL 1110
Query: 1130 FEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFF 1169
E+ + + +WI++GS LGGLLLLALLV LWKLGFF
Sbjct: 1111 LEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 820 bits (2119), Expect = 0.0
Identities = 463/1212 (38%), Positives = 703/1212 (58%), Gaps = 86/1212 (7%)
Query: 6 GLVVA--WALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLE 63
G+ VA W L++ +FN+D + G FGYTVQQ++ KW+++G+PL
Sbjct: 10 GVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLV 69
Query: 64 TNGYQKTGDVYKCPVIHGN---CTKLNLG-RVTLSNVSERKDNMRLGLSLATNPKDNSFL 119
+TGDVYKCPV G C KL+L ++ NV+E K+NM G +L TNP + FL
Sbjct: 70 GQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNP-NGGFL 128
Query: 120 ACSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWV 179
AC PL+++ CG +YTTG+CS V+ F+ ++AP +Q C T +DIVIVLDGSNSIYPW
Sbjct: 129 ACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAP-VQECSTQLDIVIVLDGSNSIYPWD 187
Query: 180 EVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTE 239
V FL ++L++ IGP Q QVG+VQYGE+V HEF+LN Y S ++V+ AA I QRGG +
Sbjct: 188 SVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQ 247
Query: 240 TRTAFGIEFARSEAFQ--KGGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAV 297
T TA GI+ AR EAF +G R+G KKVM+++TDGESHD+ L+KVIQ E +N+ R+++
Sbjct: 248 TMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSI 307
Query: 298 AVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT-N 356
A+LG YNR ++ E F+ EIK IAS+P +KHFFNV+DE AL IV LG+RIF+LE T +
Sbjct: 308 AILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATAD 367
Query: 357 KNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPE 416
++ SF +EMSQTGFS+H +D V+LGAVGAYDWNG V+ + ++ +IP ++ E +
Sbjct: 368 QSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTK 427
Query: 417 ELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQI 476
+ + +YLGYTV S +S +Y+AG PR+NHTG+VI++ M + ++ I Q + G+QI
Sbjct: 428 KNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDG-NIKILQTLSGEQI 486
Query: 477 GSYFGSEITSVDIDGDGVTDVLLVGAPMYFN-EGRERGKVYVYELRQNLFVYNGTLK--- 532
GSYFGS +T+ DID D TD+LLVGAPMY E E+GKVYVY L Q F Y +L+
Sbjct: 487 GSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIK 546
Query: 533 ---------DSHSYQN------ARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIF 577
+S + +N ARFG++IA+V+DLN D +ND+V+GAPLED+H GA+YI+
Sbjct: 547 QTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIY 606
Query: 578 HGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRP 637
HG +I K QRI + L++FG SIHG++DLN DGL D+ +G LG A + WSR
Sbjct: 607 HGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRD 666
Query: 638 VVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATM 697
V + +++FEP+K+NI ++C G++ C+ A +CF + ++Y T+
Sbjct: 667 VAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTL 726
Query: 698 DERRYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDP 757
D R R+ +R R + + + C + +F++LD D+ V +++++L DP
Sbjct: 727 DSLRQISRSFFSGTQERKVQRNITVRKSE--CTKHSFYMLDKHDFQDSVRITLDFNLTDP 784
Query: 758 DHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDC 817
++GP+LDD P ++ +PF C E C+ DL
Sbjct: 785 ENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDL-------------------------- 818
Query: 818 SAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASL--IQKEDS 875
S + + + + I+ S + V T++N ++AY+T + S NL F+ + IQK+
Sbjct: 819 SLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSC 878
Query: 876 DGSIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNE 935
+ + C V YPF R V F++ F+F+ S + ++ I L+A SDS E
Sbjct: 879 ESN----------HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEE 928
Query: 936 RDSTKEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSS----LERYDGIGPPFSCIFR 991
T DNV + +KYE + F S+S H + N + + + IG + +
Sbjct: 929 PPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYL 988
Query: 992 IQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSC------NIWGNSTEYRP 1045
I+ G FP+ + + I+ P T +G +L L+ N +C + + ++ +
Sbjct: 989 IRKSGSFPMPELKLSISFPNMTSNGYPVL-YPTGLSSSENANCRPHIFEDPFSINSGKKM 1047
Query: 1046 TPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKALKYKSMKIMV 1105
T + L+R L+ + +I CN+ ++N L+ LW + + S+ + +
Sbjct: 1048 TTSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLI--LWKPTFIKSYFSSLNLTI 1105
Query: 1106 NAALQRQFHSPFIFREEDPSRQIVFEISKQE-DWQVPIWIIVGSTLGGLLLLALLVLALW 1164
L R ++ + + R++ +ISK +VP+W+I+ S GLLLL LL+LALW
Sbjct: 1106 RGEL-RSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALW 1164
Query: 1165 KLGFFRSARRRR 1176
K+GFF+ +++
Sbjct: 1165 KIGFFKRPLKKK 1176
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 707 bits (1824), Expect = 0.0
Identities = 423/1175 (36%), Positives = 666/1175 (56%), Gaps = 71/1175 (6%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPV--IH 80
+N+ + ++ G + FGY VQQ WL+VG+P + GDVYKCPV
Sbjct: 30 YNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLST 89
Query: 81 GNCTKLNLGRVT-LSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMC 139
C KLNL T + NV+E K NM LGL L N FL C PLW+ +CG+ YYTTG+C
Sbjct: 90 ATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVC 149
Query: 140 SRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVEVQHFLINILKKFYIGPGQI 199
S ++ +F+ S + +PA Q C + +D+V+V D SNSIYPW V++FL ++ IGP +
Sbjct: 150 SDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKT 209
Query: 200 QVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--KG 257
QVG++QY + F+LN Y++ ++++ A S Q GG T T I++AR A+ G
Sbjct: 210 QVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASG 269
Query: 258 GRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEI 317
GR+ A KVM+V+TDGESHD L+ VI Q DN+ R+ +AVLGY NR ++ + + EI
Sbjct: 270 GRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEI 329
Query: 318 KYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHV-- 375
K IAS P +++FFNV+DEAAL + LG++IFS+EGT + +F +EMSQ GFS+
Sbjct: 330 KAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYSS 389
Query: 376 VEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSS 435
D ++LGAVGA+ W+G ++++TS G +I ++++ + + +NH +YLGY+V + +S+
Sbjct: 390 QNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQD--RNHSSYLGYSV-AAIST 446
Query: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
+ +VAGAPR N+TG+++L++++ N ++T+ QA RG QIGSYFGS + SVD+D D +T
Sbjct: 447 GESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTIT 506
Query: 496 DVLLVGAPMYFNE-GRERGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQ 554
DVLLVGAPMY ++ +E G+VY++ +++ + + L+ +N RFGS+IA++ D+N
Sbjct: 507 DVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPEGIENTRFGSAIAALSDINM 566
Query: 555 DSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELA--TGLQYFGCSIHGQL 612
D +NDV+VG+PLE+ ++GA+YI++G +G+I Q+I S+ A + LQYFG S+ G
Sbjct: 567 DGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYG 626
Query: 613 DLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAF 672
DLN D + D+++GA G V LWS+ + + F P KI + +++ + +
Sbjct: 627 DLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKITLVNKNAQ--------IILK 678
Query: 673 LCFTPIFLAPHFQTTTVGIRYNATMD----ERRYTPRAHLDEGGDRFTNRAVLLSSGQEL 728
LCF+ F P Q V I YN T+D R T R E +R + ++++ Q
Sbjct: 679 LCFSAKF-RPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSC 737
Query: 729 CERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCV 788
E I ++ + +D V + V+ SLE+P P L+ T S+PF C ED C+
Sbjct: 738 PEHI-IYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCI 796
Query: 789 PDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRG 848
DLVLD R +P A E FI+ + +R+ TL+N+
Sbjct: 797 SDLVLDVR-QIPAAQE----------------------QPFIVSNQNKRLTFSVTLKNKR 833
Query: 849 ENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQV-CNVSYPFFRAKAKVA 907
E+AY+T + + S NL FAS D E + QK V C+V YP + + +V
Sbjct: 834 ESAYNTGIVVDFSENLFFASFSLPVD---GTEVTCQVAASQKSVACDVGYPALKREQQVT 890
Query: 908 FRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSSLSH 967
F ++F+F+ + + A S+S E + K DN+ L+ L Y+A++ TRS++++
Sbjct: 891 FTINFDFNLQNLQNQASLSFQALSESQEEN--KADNLVNLKIPLLYDAEIHLTRSTNINF 948
Query: 968 YEVKPN----SSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLR 1023
YE+ + S + ++ +GP F ++ G P+ + I IP T+ N L+ L
Sbjct: 949 YEISSDGNVPSIVHSFEDVGPKFIFSLKV-TTGSVPVSMATVIIHIPQYTKEKNPLMYLT 1007
Query: 1024 DFLTDEA-NTSCNIWGNSTEYRPTP-----VEEDLRRAPQLNHSNSDVVSINCNIRLVPN 1077
TD+A + SCN N + T E+ R +LN + ++ C ++ V
Sbjct: 1008 GVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHM 1067
Query: 1078 Q-EINFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISK-Q 1135
+ E ++ +W + + +++ + + AA + ++P I+ ED + I I K
Sbjct: 1068 KGEYFVNVTTRIWNGTFASSTFQT--VQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPD 1125
Query: 1136 EDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
E +VP +I+GS + G+LLL LV LWKLGFF+
Sbjct: 1126 EKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFK 1160
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 399 bits (1025), Expect = e-111
Identities = 341/1188 (28%), Positives = 548/1188 (46%), Gaps = 116/1188 (9%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
FN+D +P + F G +V Q G LVVGAPLE +TG +Y C G
Sbjct: 18 FNLDVEEPTIFQEDAGGF-GQSVVQF---GGSRLVVGAPLEVVAANQTGRLYDCAAATGM 73
Query: 83 CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142
C + L ++ NM LGL+LA + + LAC P CG + Y+ G C +
Sbjct: 74 CQPIPL------HIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSCLLL 127
Query: 143 NSNFRFSKTVAPALQRC-QTYMDIVIVLDGSNSI--YPWVEVQHFLINILKKFYIGPGQI 199
S + +TV A C MDIV ++DGS SI + +++ F+ ++ +F G +
Sbjct: 128 GSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE-GTDTL 186
Query: 200 QVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKG 257
++QY + F +R+ I Q G T TA GI ++ F + G
Sbjct: 187 -FALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGL-TFTATGILTVVTQLFHHKNG 244
Query: 258 GRKGAKKVMIVITDGESHDSP-DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNE 316
RK AKK++IVITDG+ + P + VI Q+E+ + RYA+ V T E
Sbjct: 245 ARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGV-----GHAFQGPTARQE 299
Query: 317 IKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT-NKNETSFGLEMSQTGFSSHV 375
+ I+S P H F V + AAL I L ++I+++EGT ++ +SF EMSQ GFS+ +
Sbjct: 300 LNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTAL 359
Query: 376 VEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSS 435
DG+ LGAVG++ W+G + +++ E + +YLGY+ T +
Sbjct: 360 TMDGLFLGAVGSFSWSGGAFLYPPN-----MSPTFINMSQENVDMRDSYLGYS-TELALW 413
Query: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
+ + V GAPR+ HTGK ++FT + R + G QIGSYFG+ + SVD+D DG T
Sbjct: 414 KGVQNLVLGAPRYQHTGKAVIFTQVS-RQWRKKAEVTGTQIGSYFGASLCSVDVDSDGST 472
Query: 496 DVLLVGAPMYFNEGRERGKVYVYELRQNLFVY--NGTLKDSHSYQNARFGSSIASVRDLN 553
D++L+GAP Y+ + R G+V V L + + + L+ + RFG+++ + D+N
Sbjct: 473 DLILIGAPHYYEQTRG-GQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVN 531
Query: 554 QDSYNDVVVGAPLEDNHAGAIYIFHGFRGS-ILKTPKQRITASELATGLQYFGCSIHGQL 612
+D DV +GAP E + GA+Y+FHG S I + QRI +S+L+ LQYFG ++ G
Sbjct: 532 EDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQ 591
Query: 613 DLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDC---KRSGRDATCL 669
DL +DGL+DLAVGA G ++L S PV+++ ++ F P ++ C K S +A
Sbjct: 592 DLTQDGLMDLAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDA 651
Query: 670 AAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQELC 729
L L +R++ +D R T RA +E + R L G C
Sbjct: 652 TVCLTIQKSSL-DQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIH-C 709
Query: 730 ERINFHVLDTA-DYVKPVTFSVEYSL------EDPDHGPMLDDGWPTTLRVSVPFWNGCN 782
E + + D D V P+ + +SL + P+L G S+PF C
Sbjct: 710 ETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCG 769
Query: 783 EDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEA 842
+D C DL TLSF + + + V
Sbjct: 770 QDGLCEGDL---------------------------GVTLSFSGLQTLTVGSSLELNVIV 802
Query: 843 TLENRGENAYSTVLNISQSANLQF--ASLIQKEDSDGSIECV-----NEERRLQKQVCNV 895
T+ N GE++Y TV+++ A L S QK+ ++ E+ L+ C+V
Sbjct: 803 TVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSV 862
Query: 896 SYPFFRAKAKVAFRLDFEFS-KSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYE 954
++P F + F + F+ S K+ + + +A S++N+ S+K L +KY
Sbjct: 863 NHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSKA--TFQLELPVKYA 920
Query: 955 ADVLFTRSSSLSHY-------EVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKI 1007
+ +R + Y E K + RY R+ NL + + +
Sbjct: 921 VYTMISRQEESTKYFNFATSDEKKMKEAEHRY-----------RVNNLSQRDL-AISINF 968
Query: 1008 TIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVS 1067
+P+ + + D + + + S + + + R+P L+ S +D +
Sbjct: 969 WVPVLLNG----VAVWDVVMEAPSQSLPCVSERKPPQHSDFLTQISRSPMLDCSIADCLQ 1024
Query: 1068 INCNI-RLVPNQEINFHLLGNL---WLRSLKALKYKSMKIMV-NAALQRQFHSPFIFREE 1122
C++ +E++F L GNL W+R + L+ K + + V +S +E
Sbjct: 1025 FRCDVPSFSVQEELDFTLKGNLSFGWVR--ETLQKKVLVVSVAEITFDTSVYSQLPGQEA 1082
Query: 1123 DPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
Q+ + + E + I II+GS++G LLLLAL+ L+KLGFF+
Sbjct: 1083 FMRAQMEMVLEEDEVYNA-IPIIMGSSVGALLLLALITATLYKLGFFK 1129
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 399 bits (1024), Expect = e-110
Identities = 337/1191 (28%), Positives = 553/1191 (46%), Gaps = 119/1191 (9%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
FN+DT + +A FG +V Q+ N W+VVGAP + +TG +Y+C G
Sbjct: 20 FNLDTEELTAFRVD-SAGFGDSVVQY---ANSWVVVGAPQKITAANQTGGLYQCGYSTGA 75
Query: 83 CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142
C + L V NM LGLSLA+ + LAC P HECG + Y TG+C +
Sbjct: 76 CEPIGL------QVPPEAVNMSLGLSLASTTSPSQLLACGPTVHHECGRNMYLTGLCFLL 129
Query: 143 NSNFRFSKTVAPALQRC-QTYMDIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQI 199
+ ++ + + Q C + DIV ++DGS SI + + +F+ ++ +F
Sbjct: 130 GPT-QLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ--RPST 186
Query: 200 QVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQ-RGGTETRTAFGIEFARSEAFQKGG 258
Q ++Q+ F ++R + + + + Q +G T T TA R G
Sbjct: 187 QFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGA 246
Query: 259 RKGAKKVMIVITDGESH-DSPDLEKVIQQSERDNVTRYAVAV-LGYYNRRGINPETFLNE 316
R+ A K++IVITDG+ DS D + VI ++ + RYA+ V L + NR E
Sbjct: 247 RRDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNS------WKE 300
Query: 317 IKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNK-NETSFGLEMSQTGFSSHV 375
+ IAS P +H F V D ALKDI + L ++IF++EGT + +SF LEM+Q GFS+
Sbjct: 301 LNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVF 360
Query: 376 VEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSS 435
DG +LGAVG++ W+G + +++ E + +YLGY+ T +
Sbjct: 361 TPDGPVLGAVGSFTWSGGAFLYPPN-----MSPTFINMSQENVDMRDSYLGYS-TELALW 414
Query: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
+ + V GAPR+ HTGK ++FT + R + + G QIGSYFG+ + SVD+D DG T
Sbjct: 415 KGVQSLVLGAPRYQHTGKAVIFTQVS-RQWRMKAEVTGTQIGSYFGASLCSVDVDSDGST 473
Query: 496 DVLLVGAPMYFNEGRERGKVYVYELRQNLFVY--NGTLKDSHSYQNARFGSSIASVRDLN 553
D++L+GAP Y+ + R G+V V L + + + L + RFG+++ + D+N
Sbjct: 474 DLVLIGAPHYYEQTRG-GQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVN 532
Query: 554 QDSYNDVVVGAPLEDNHAGAIYIFHGFRG-SILKTPKQRITASELATGLQYFGCSIHGQL 612
D DVV+GAP E+ + GA+Y+FHG G SI + QRI S+L++ LQYFG ++ G
Sbjct: 533 GDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQ 592
Query: 613 DLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCKRSG-RDATCLAA 671
DL +DGL+DLAVGA G ++L +RPV+ + S+ F P++I +C+ + T + +
Sbjct: 593 DLTQDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQS 652
Query: 672 FLCFTPIFLAPHF---QTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQEL 728
+C + + + + + +D R +PRA E +R +R +L
Sbjct: 653 NICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAH- 711
Query: 729 CERINFHVLDTA-DYVKPVTFSVEYSLEDP------DHGPMLDDGWPTTLRVSVPFWNGC 781
CE N + D V P+T + ++L + PML S+PF C
Sbjct: 712 CENFNLLLPSCVEDSVTPITLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNC 771
Query: 782 NEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVE 841
D C QD + SF ++ + + E
Sbjct: 772 GADHIC---------------------------QDNLGISFSFPGLKSLLVGSNLELNAE 804
Query: 842 ATLENRGENAYSTVLNISQSANLQFASLI--QKEDSDGSIECVNEERRLQKQ-----VCN 894
+ N GE++Y T + S A L + + QK+ S+ + + Q C
Sbjct: 805 VMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCR 864
Query: 895 VSYPFFRAKAKVAFRLDFEFS-KSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKY 953
+++ FR A++ F F+ S K++ L + S++N ++K L +KY
Sbjct: 865 INHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSK--TTFQLELPVKY 922
Query: 954 EADVL------FTRSSSLSHYEVKPNS-SLERYDGIGPPFSCIFRIQNLGLFPIHGMMMK 1006
+ FT+ + S E K + ++ RY ++ NLG + + +
Sbjct: 923 AVYTVVSSHEQFTKYLNFSESEEKESHVAMHRY-----------QVNNLGQRDLP-VSIN 970
Query: 1007 ITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDL---RRAPQLNHSNS 1063
+P+ + + + C S+E P + L ++ P L+ S +
Sbjct: 971 FWVPVELNQEAVWMDVEVSHPQNPSLRC-----SSEKIAPPASDFLAHIQKNPVLDCSIA 1025
Query: 1064 DVVSINCNI-RLVPNQEINFHLLGNL---WLRSLKALKYKSMKIMVNAALQRQFHSPFIF 1119
+ C++ +E++F L GNL W+R + K + + +S
Sbjct: 1026 GCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSV-AEITFDTSVYSQLPG 1084
Query: 1120 REEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
+E Q + K + P +IVGS++GGLLLLAL+ L+K+GFF+
Sbjct: 1085 QEAFMRAQTTTVLEKYKVHN-PTPLIVGSSIGGLLLLALITAVLYKVGFFK 1134
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 392 bits (1007), Expect = e-108
Identities = 359/1222 (29%), Positives = 566/1222 (46%), Gaps = 149/1222 (12%)
Query: 8 VVAWALSLWPGF-----TDTFNMDTRKPRVIPGSRTA-FFGYTVQQHDISGNKWLVVGAP 61
+ A++L GF ++N+D R R R FGY V Q GN ++VGAP
Sbjct: 6 ITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQ---VGNG-VIVGAP 61
Query: 62 LETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLAC 121
E N TG +Y+C G+C + L SN + + LG++LAT+P D S LAC
Sbjct: 62 GEGNS---TGSLYQCQSGTGHCLPVTLRG---SNYTSKY----LGMTLATDPTDGSILAC 111
Query: 122 SPLWSHECGSSYYTTGMCSRVNSNFRFSKTVA-PALQRC-QTYMDIVIVLDGSNSIYP-- 177
P S C + Y +G+C N + P Q C + +D+V + DGS S+ P
Sbjct: 112 DPGLSRTCDQNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDE 171
Query: 178 WVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGG 237
+ ++ F+ +++KK + Q VQ+ EF +DY KD H++
Sbjct: 172 FQKILDFMKDVMKK--LSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML- 228
Query: 238 TETRTAFGIEFARSEAFQK--GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRY 295
T T I + +E F++ G R A KV+I+ITDGE+ DS +++ ++ RY
Sbjct: 229 LLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRY 282
Query: 296 AVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT 355
+ + ++ + + ET + AS P + + LKD+ L +I+ +EGT
Sbjct: 283 IIGIGKHFQTKE-SQET----LHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGT 337
Query: 356 NKNE-TSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEF 414
+K + TSF +E+S +G S+ + ++GAVGA DW G L K ++++
Sbjct: 338 SKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDL----KADLQDDTFIGNE 393
Query: 415 PEELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTM-----HNNRSLTIHQ 469
P + YLGYTVT + S ++ + +GAPR+ H G+V+LF H ++ TIH
Sbjct: 394 PLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIH- 452
Query: 470 AMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG 529
G QIGSYFG E+ VD+D DG T++LL+GAP+++ E R G+V++Y+ RQ F
Sbjct: 453 ---GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-GRVFIYQRRQLGFEEVS 508
Query: 530 TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPK 589
L+ Y RFG +I ++ D+N D DV VGAPLE+ GA+YIF+G G + P
Sbjct: 509 ELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPS 566
Query: 590 QRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEP 649
QRI +++ +G+Q+FG SIHG DL DGL D+AVGA ++L SRPVV + + F P
Sbjct: 567 QRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSP 626
Query: 650 SKINIFHRDC--KRSGRDATCLAAFLCFTPIFLAPHFQTTTV-GIRYNATMDERRYTPRA 706
++I + +C S + + +CF L P FQ V + Y +D R T R
Sbjct: 627 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHR-TRRR 685
Query: 707 HLDEGGDRFTNRAVLLSSGQELCERINFHV-LDTADYVKPVTFSVEYSLEDPDHGP---- 761
L GG R + +++ C +FH + D + P+ S+ +SL + + P
Sbjct: 686 GLFPGGRHELRRNIAVTTSMS-CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR 744
Query: 762 MLDDGWPTTLRVS-------VPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPA 814
P LR S +PF C ED+ C +L RV PA
Sbjct: 745 AQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANL----------------RVSFSPA 788
Query: 815 QDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASL-IQKE 873
+ + +F + ++VE +L N E+AY L++ L F + + K
Sbjct: 789 RSRALRLTAFAS-----------LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKP 837
Query: 874 DSDGSIEC--VNEERRLQKQV--CNVSYPFFRAKAKVAFRLDF------EFSKSIFLHHL 923
S + C + EE RL + CNVS P F+A VA ++ F + S+ LH
Sbjct: 838 HSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELH-- 895
Query: 924 EIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSLERYDGIG 983
A + +NE EDN A + Y ++L ++ Y
Sbjct: 896 ----ANVTCNNEDSDLLEDNSATTIIPILYPINIL-----------IQDQEDSTLYVSFT 940
Query: 984 PPFSCIFRIQNLGLFPIHGMMMKITIP-IATRSGNRLLKLRDFLTDEANTSCNIWGNSTE 1042
P I +++++ I + IP + G +T + W E
Sbjct: 941 PKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQ-------WSVQME 993
Query: 1043 YRPTPVE-EDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWL-RSLKALKYKS 1100
P P EDL R P C + V QEI ++G L L ++A S
Sbjct: 994 -PPVPCHYEDLERLPDAAEPCLPGALFRCPV--VFRQEILVQVIGTLELVGEIEASSMFS 1050
Query: 1101 M--KIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLAL 1158
+ + ++ + FH ++ Q+V ++ + Q+ +++ V S +GGLLLL L
Sbjct: 1051 LCSSLSISFNSSKHFH---LYGSNASLAQVVMKVDVVYEKQM-LYLYVLSGIGGLLLLLL 1106
Query: 1159 LVLALWKLGFF-RSARRRREPG 1179
+ + L+K+GFF R+ + + E G
Sbjct: 1107 IFIVLYKVGFFKRNLKEKMEAG 1128
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 380 bits (977), Expect = e-105
Identities = 340/1197 (28%), Positives = 541/1197 (45%), Gaps = 127/1197 (10%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
FN+DT + F VQ + G++ +VVGAP E + G +Y+C G+
Sbjct: 17 FNLDTENAMTFQENARGFGQSVVQ---LQGSR-VVVGAPQEIVAANQRGSLYQCDYSTGS 72
Query: 83 CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142
C + L V NM LGLSLA LAC P C + Y G+C
Sbjct: 73 CEPIRL------QVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLF 126
Query: 143 NSNFRFSKTVAP-ALQRC-QTYMDIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQ 198
SN R P AL+ C Q DI ++DGS SI P + ++ F+ ++++ + +
Sbjct: 127 GSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQ--LKKSK 184
Query: 199 IQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--K 256
++QY E+ F ++++ + I Q G T TA GI E F
Sbjct: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLG-RTHTATGIRKVVRELFNITN 243
Query: 257 GGRKGAKKVMIVITDGESHDSP-DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLN 315
G RK A K+++VITDGE P E VI +++R+ V RY + V + E
Sbjct: 244 GARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRS-----EKSRQ 298
Query: 316 EIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNK-NETSFGLEMSQTGFSSH 374
E+ IAS P H F V + ALK I + L ++IF++EGT + +SF EMSQ GFS+
Sbjct: 299 ELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAA 358
Query: 375 VVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVS 434
+ +G LL VG+YDW G V TS K +++ + + AYLGY ++
Sbjct: 359 ITSNGPLLSTVGSYDWAGGVFLYTSKEK-----STFINMTRVDSDMNDAYLGYAAAIILR 413
Query: 435 SRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGV 494
+R + V GAPR+ H G V +F N + ++G QIG+YFG+ + SVD+D +G
Sbjct: 414 NRVQSL-VLGAPRYQHIGLVAMFRQ-NTGMWESNANVKGTQIGAYFGASLCSVDVDSNGS 471
Query: 495 TDVLLVGAPMYFNEGRERGKVYVYEL---RQNLFVYNGTLKDSHSYQNARFGSSIASVRD 551
TD++L+GAP Y+ + R G+V V L ++ + + L RFG+++ + D
Sbjct: 472 TDLVLIGAPHYYEQTRG-GQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGD 530
Query: 552 LNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGS-ILKTPKQRITASELATGLQYFGCSIHG 610
+N D DV +GAP E+++ GA+Y+FHG GS I + QRI S+L+ LQYFG S+ G
Sbjct: 531 VNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSG 590
Query: 611 QLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKI--NIFHRDC-------KR 661
DL DGL+DL VGA G+ ++L S+PV+++ A + F P ++ N+F +C K
Sbjct: 591 GQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVF--ECNDQVVKGKE 648
Query: 662 SGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVL 721
+G CL Q+ + Y+ +D R RA +E + T R
Sbjct: 649 AGEVRVCLHVQKSTRDRLREGQIQSV---VTYDLALDSGRPHSRAVFNETKNS-TRRQTQ 704
Query: 722 LSSGQELCERINFHVLD-TADYVKPVTFSVEYSLEDP------DHGPMLDDGWPTTLRVS 774
+ + CE + + + D V P+ + +SL + P+L +
Sbjct: 705 VLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTAL 764
Query: 775 VPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIEST 834
PF C D C DL + T SF + ++
Sbjct: 765 FPFEKNCGNDNICQDDL---------------------------SITFSFMSLDCLVVGG 797
Query: 835 RQRVAVEATLENRGENAYSTVLNISQSANLQF--ASLIQKEDSDGSIECVNEER------ 886
+ V T+ N GE++Y T + +L + S +Q + S S E
Sbjct: 798 PREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVS 857
Query: 887 -RLQKQVCNVSYPFFRAKAKVAFRLDFEF-SKSIFLHHLEIELAAGSDSNERDSTKEDNV 944
L+ C++++P F ++V F + F+ SK+ + L ++ S++N + K +
Sbjct: 858 GALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTE-- 915
Query: 945 APLRFHLKYEADVLFTR---SSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIH 1001
L +KY ++ T S+ ++ N+S +++ NLG
Sbjct: 916 FQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQ--------YQVSNLGQ---R 964
Query: 1002 GMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHS 1061
+ + + + R ++ R +T N S + +LR+AP +N S
Sbjct: 965 SLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCS 1024
Query: 1062 NSDVVSINCNIRLVP-NQEINFHLLGNL---WLRSLK---ALKYKSMKIMVNAALQRQFH 1114
+ I C+I +E N L GNL W L + +I+ N ++
Sbjct: 1025 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1084
Query: 1115 SPFIF-REEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
F R + ++ FE+ P+ +IVGS++GGLLLLAL+ AL+KLGFF+
Sbjct: 1085 GQGAFVRSQTETKVEPFEVPN------PLPLIVGSSVGGLLLLALITAALYKLGFFK 1135
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 380 bits (977), Expect = e-105
Identities = 340/1196 (28%), Positives = 540/1196 (45%), Gaps = 126/1196 (10%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
FN+DT + F VQ + G++ +VVGAP E + G +Y+C G+
Sbjct: 17 FNLDTENAMTFQENARGFGQSVVQ---LQGSR-VVVGAPQEIVAANQRGSLYQCDYSTGS 72
Query: 83 CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142
C + L V NM LGLSLA LAC P C + Y G+C
Sbjct: 73 CEPIRL------QVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLF 126
Query: 143 NSNFRFSKTVAP-ALQRC-QTYMDIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQ 198
SN R P AL+ C Q DI ++DGS SI P + ++ F+ ++++ + +
Sbjct: 127 GSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQ--LKKSK 184
Query: 199 IQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--K 256
++QY E+ F ++++ + I Q G T TA GI E F
Sbjct: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLG-RTHTATGIRKVVRELFNITN 243
Query: 257 GGRKGAKKVMIVITDGESHDSP-DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLN 315
G RK A K+++VITDGE P E VI +++R+ V RY + V + E
Sbjct: 244 GARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRS-----EKSRQ 298
Query: 316 EIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNK-NETSFGLEMSQTGFSSH 374
E+ IAS P H F V + ALK I + L ++IF++EGT + +SF EMSQ GFS+
Sbjct: 299 ELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAA 358
Query: 375 VVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVS 434
+ +G LL VG+YDW G V TS K +++ + + AYLGY ++
Sbjct: 359 ITSNGPLLSTVGSYDWAGGVFLYTSKEK-----STFINMTRVDSDMNDAYLGYAAAIILR 413
Query: 435 SRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGV 494
+R + V GAPR+ H G V +F N + ++G QIG+YFG+ + SVD+D +G
Sbjct: 414 NRVQSL-VLGAPRYQHIGLVAMFRQ-NTGMWESNANVKGTQIGAYFGASLCSVDVDSNGS 471
Query: 495 TDVLLVGAPMYFNEGRERGKVYVYELRQNLFVY--NGTLKDSHSYQNARFGSSIASVRDL 552
TD++L+GAP Y+ + R G+V V L + + + L RFG+++ + D+
Sbjct: 472 TDLVLIGAPHYYEQTRG-GQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDV 530
Query: 553 NQDSYNDVVVGAPLEDNHAGAIYIFHGFRGS-ILKTPKQRITASELATGLQYFGCSIHGQ 611
N D DV +GAP E+++ GA+Y+FHG GS I + QRI S+L+ LQYFG S+ G
Sbjct: 531 NGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGG 590
Query: 612 LDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKI--NIFHRDC-------KRS 662
DL DGL+DL VGA G+ ++L S+PV+++ A + F P ++ N+F +C K +
Sbjct: 591 QDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVF--ECNDQVVKGKEA 648
Query: 663 GRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLL 722
G CL Q+ + Y+ +D R RA +E + T R +
Sbjct: 649 GEVRVCLHVQKSTRDRLREGQIQSV---VTYDLALDSGRPHSRAVFNETKNS-TRRQTQV 704
Query: 723 SSGQELCERINFHVLD-TADYVKPVTFSVEYSLEDP------DHGPMLDDGWPTTLRVSV 775
+ CE + + + D V P+ + +SL + P+L +
Sbjct: 705 LGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALF 764
Query: 776 PFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTR 835
PF C D C DL + T SF + ++
Sbjct: 765 PFEKNCGNDNICQDDL---------------------------SITFSFMSLDCLVVGGP 797
Query: 836 QRVAVEATLENRGENAYSTVLNISQSANLQF--ASLIQKEDSDGSIECVNEER------- 886
+ V T+ N GE++Y T + +L + S +Q + S S E
Sbjct: 798 REFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857
Query: 887 RLQKQVCNVSYPFFRAKAKVAFRLDFEF-SKSIFLHHLEIELAAGSDSNERDSTKEDNVA 945
L+ C++++P F ++V F + F+ SK+ + L ++ S++N + K +
Sbjct: 858 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTE--F 915
Query: 946 PLRFHLKYEADVLFTR---SSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHG 1002
L +KY ++ T S+ ++ N+S +++ NLG
Sbjct: 916 QLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQ--------YQVSNLGQ---RS 964
Query: 1003 MMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSN 1062
+ + + + R ++ R +T N S + +LR+AP +N S
Sbjct: 965 LPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSI 1024
Query: 1063 SDVVSINCNIRLVP-NQEINFHLLGNL---WLRSLK---ALKYKSMKIMVNAALQRQFHS 1115
+ I C+I +E N L GNL W L + +I+ N ++
Sbjct: 1025 AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPG 1084
Query: 1116 PFIF-REEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
F R + ++ FE+ P+ +IVGS++GGLLLLAL+ AL+KLGFF+
Sbjct: 1085 QGAFVRSQTETKVEPFEVPN------PLPLIVGSSVGGLLLLALITAALYKLGFFK 1134
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 328 bits (841), Expect = 2e-89
Identities = 298/1022 (29%), Positives = 471/1022 (46%), Gaps = 122/1022 (11%)
Query: 197 GQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQK 256
G I VQ+ EF +DY KD H++ T T I + +E F++
Sbjct: 106 GSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML-LLTNTFGAINYVATEVFRE 164
Query: 257 --GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFL 314
G R A KV+I+ITDGE+ DS +++ ++ RY + + ++ + + ET
Sbjct: 165 ELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRYIIGIGKHFQTKE-SQET-- 215
Query: 315 NEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNE-TSFGLEMSQTGFSS 373
+ AS P + + LKD+ L +I+ +EGT+K + TSF +E+S +G S+
Sbjct: 216 --LHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISA 273
Query: 374 HVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVV 433
+ ++GAVGA DW G L K ++++ P + YLGYTVT +
Sbjct: 274 DLSRGHAVVGAVGAKDWAGGFLDL----KADLQDDTFIGNEPLTPEVRAGYLGYTVTWLP 329
Query: 434 SSRQGRVYVAGAPRFNHTGKVILFTM-----HNNRSLTIHQAMRGQQIGSYFGSEITSVD 488
S ++ + +GAPR+ H G+V+LF H ++ TIH G QIGSYFG E+ VD
Sbjct: 330 SRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIH----GTQIGSYFGGELCGVD 385
Query: 489 IDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIAS 548
+D DG T++LL+GAP+++ E R G+V++Y+ RQ F L+ Y RFG +I +
Sbjct: 386 VDQDGETELLLIGAPLFYGEQRG-GRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITA 444
Query: 549 VRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSI 608
+ D+N D DV VGAPLE+ GA+YIF+G G + P QRI +++ +G+Q+FG SI
Sbjct: 445 LTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSI 502
Query: 609 HGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDC--KRSGRDA 666
HG DL DGL D+AVGA ++L SRPVV + + F P++I + +C S +
Sbjct: 503 HGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMK 562
Query: 667 TCLAAFLCFTPIFLAPHFQTTTV-GIRYNATMDERRYTPRAHLDEGGDRFTNRAVLLSSG 725
+ +CF L P FQ V + Y +D R T R L GG R + +++
Sbjct: 563 EGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHR-TRRRGLFPGGRHELRRNIAVTTS 621
Query: 726 QELCERINFHV-LDTADYVKPVTFSVEYSLEDPDHGP---MLDDGWPTTLRVS------- 774
C +FH + D + P+ S+ +SL + + P P LR S
Sbjct: 622 MS-CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWE 680
Query: 775 VPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIEST 834
+PF C ED+ C +L RV PA+ + +F +
Sbjct: 681 IPFEKNCGEDKKCEANL----------------RVSFSPARSRALRLTAFAS-------- 716
Query: 835 RQRVAVEATLENRGENAYSTVLNISQSANLQFASL-IQKEDSDGSIEC--VNEERRLQKQ 891
++VE +L N E+AY L++ L F + + K S + C + EE RL +
Sbjct: 717 ---LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSR 773
Query: 892 V--CNVSYPFFRAKAKVAFRLDF------EFSKSIFLHHLEIELAAGSDSNERDSTKEDN 943
CNVS P F+A VA ++ F + S+ LH A + +NE EDN
Sbjct: 774 ALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELH------ANVTCNNEDSDLLEDN 827
Query: 944 VAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGM 1003
A + Y ++L ++ Y P I +++++ I
Sbjct: 828 SATTIIPILYPINIL-----------IQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPS 876
Query: 1004 MMKITIP-IATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE-EDLRRAPQLNHS 1061
+ IP + G +T + W E P P EDL R P
Sbjct: 877 IHDHNIPTLEAVVGVPQPPSEGPITHQ-------WSVQME-PPVPCHYEDLERLPDAAEP 928
Query: 1062 NSDVVSINCNIRLVPNQEINFHLLGNLWL-RSLKALKYKSM--KIMVNAALQRQFHSPFI 1118
C + V QEI ++G L L ++A S+ + ++ + FH +
Sbjct: 929 CLPGALFRCPV--VFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFH---L 983
Query: 1119 FREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFF-RSARRRRE 1177
+ Q+V ++ + Q+ +++ V S +GGLLLL L+ + L+K+GFF R+ + + E
Sbjct: 984 YGSNASLAQVVMKVDVVYEKQM-LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1042
Query: 1178 PG 1179
G
Sbjct: 1043 AG 1044
Score = 44.3 bits (103), Expect = 7e-04
Identities = 40/118 (33%), Positives = 57/118 (48%), Gaps = 20/118 (16%)
Query: 8 VVAWALSLWPGF-----TDTFNMDTRKPRVIPGSRTA-FFGYTVQQHDISGNKWLVVGAP 61
+ A++L GF ++N+D R R R FGY V Q GN ++VGAP
Sbjct: 6 ITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQ---VGNG-VIVGAP 61
Query: 62 LETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFL 119
E N TG +Y+C G+C + L SN + + LG++LAT+P D S L
Sbjct: 62 GEGNS---TGSLYQCQSGTGHCLPVTLRG---SNYTSKY----LGMTLATDPTDGSIL 109
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 313 bits (801), Expect = 8e-85
Identities = 293/1036 (28%), Positives = 469/1036 (45%), Gaps = 113/1036 (10%)
Query: 164 DIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRS 221
+I I+LDGS SI P + + F+ N+++ FY + +VQYG + EF L D +
Sbjct: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
Query: 222 VKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKGGRKGAKKVMIVITDGESHDSP- 278
V + +I Q G T+TA ++ F G R+ A KVM+V+TDG + P
Sbjct: 262 VMASLARVQNITQVGSV-TKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
Query: 279 DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAAL 338
+L VI + V R+A+ V E+ IASDPD+ H F VT+ AL
Sbjct: 321 NLTTVINSPKMQGVERFAIGV-----GEEFKSARTARELNLIASDPDETHAFKVTNYMAL 375
Query: 339 KDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVED-GVLLGAVGAYDWN-GAVLK 396
++ L I S+EGT + + +++Q GFS+ ++++ VLLGAVGA+DW+ GA+L
Sbjct: 376 DGLLSKLRYNIISMEGTVGDALHY--QLAQIGFSAQILDERQVLLGAVGAFDWSGGALLY 433
Query: 397 ETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVIL 456
+T + + L ++ E + +YLGY V +V+ Y+AGAPR+ H G V
Sbjct: 434 DTRSRRGRFLNQTAAAAADAEAAQY-SYLGYAV-AVLHKTCSLSYIAGAPRYKHHGAVFE 491
Query: 457 FTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVY 516
R + + G+Q+GSYFGSE+ VDID DG TD LLV AP Y G E G+VY
Sbjct: 492 L-QKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHG-EEGRVY 549
Query: 517 VYEL--RQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHA--- 571
VY L + F L + NARFG ++A++ DL+QD DV +GAPLE A
Sbjct: 550 VYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDG 609
Query: 572 ---GAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALG 628
G++YI++G + +P QRI AS +A GLQYFG S+ G D++ DGL D+ VG LG
Sbjct: 610 ASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLG 669
Query: 629 NAVILWSRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLAPHFQTTT 688
AV+ SRPVV++ S+ F PS + I + LCF + ++
Sbjct: 670 QAVVFRSRPVVRLKVSMAFTPSALPIGFNG---------VVNVRLCFEISSVTTASESGL 720
Query: 689 VGIRYNATMDERRYTPRAHLDEGGDRFTNRAVL-LSSGQELCERI----NFHVLDTADYV 743
N T+D R L R + SSG +LCE + L D
Sbjct: 721 REALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCF 780
Query: 744 KPVTFSVEYSLEDP----DH-GPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSD 798
+ V Y L+ P DH P+LD +P+ C CV +L L
Sbjct: 781 SNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQL----- 835
Query: 799 LPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNI 858
A T+S ++ + + + L N GE++Y T + +
Sbjct: 836 --------------------ATTVSQQE---LVVGLTKELTLNINLTNSGEDSYMTSMAL 872
Query: 859 SQSANLQFASLIQKEDSDGSIECVNEERRLQKQV--CNVSYPFFRAKAKVAFRLDFEFSK 916
+ NLQ + QK S +I+C + + + C + +P + ++ + ++ +
Sbjct: 873 NYPRNLQLKRM-QKPPSP-NIQCDDPQPVASVLIMNCRIGHPVLK-RSSAHVSVVWQLEE 929
Query: 917 SIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSL 976
+ F + ++SNER S L E L R ++ +
Sbjct: 930 NAFPNRTADITVTVTNSNERRS------------LANETHTLQFRHGFVAVLSKPSIMYV 977
Query: 977 ERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNI 1036
G+ +F + LF ++I +P R G +++ ++ +A+T C
Sbjct: 978 NTGQGLSHHKEFLFHVHGENLFGAE-YQLQICVPTKLR-GLQVVAVKKLTRTQASTVCT- 1034
Query: 1037 WG--NSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLK 1094
W + Y E+ + S+ + V++ I ++E+ L+ +
Sbjct: 1035 WSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEEL---------LKDVT 1085
Query: 1095 ALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLL 1154
L+ +I N +L ++ E+ +I K E + + II+ ++GGLL
Sbjct: 1086 ELQILG-EISFNKSLYEGLNA------ENHRTKITVVFLKDEKYH-SLPIIIKGSVGGLL 1137
Query: 1155 LLALLVLALWKLGFFR 1170
+L ++++ L+K GFF+
Sbjct: 1138 VLIVILVILFKCGFFK 1153
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 250 bits (638), Expect = 6e-66
Identities = 243/865 (28%), Positives = 394/865 (45%), Gaps = 101/865 (11%)
Query: 368 QTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRES-YLKEFPEELKNHG-AYL 425
Q G + E+ V++GA G++ W G + KV+ L ++ YLK E + N YL
Sbjct: 195 QAGIAGFFTEELVVMGAPGSFYWAGTI-------KVLNLTDNTYLKLNDEVIMNRRYTYL 247
Query: 426 GYTVTSVVSSRQGRV-YVAGAPRFNHTGKVILFTMHNNRSLTIHQAMR--GQQIGSYFGS 482
GY VT+ S + V GAP+ GKV +F + RS T+ + + G+++GSYFGS
Sbjct: 248 GYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRA-DRRSGTLIKIFQASGKKMGSYFGS 306
Query: 483 EITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNARF 542
+ +VD++GDG++D LLVGAPM F+E R+ G+V VY R N + NA F
Sbjct: 307 SLCAVDLNGDGLSD-LLVGAPM-FSEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHF 364
Query: 543 GSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQ 602
G SIAS+ DL+ D + DV +GAP ED+ AGA+YI+HG G I+ +++ ++ L+
Sbjct: 365 GESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLR 424
Query: 603 YFGCSIHGQLDLNEDGLIDLAVGAL--GNAVILWSRPVVQINASLHFEPSKINIFHRDCK 660
FG SI G +D++ +G D+ VGA + V+L +RPV+ ++ S+ F P INI C
Sbjct: 425 MFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQCH 483
Query: 661 RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMD----ERRYTPRAHLDEGGDRF- 715
+ CL CF+ F H +G+ Y D E+ PR + G+
Sbjct: 484 DGQQPVNCLNVTTCFS--FHGKHV-PGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMG 540
Query: 716 -TNRAVLLSSGQELCERINFHV-LDTADYVKPVTFSVEYSLED----------PDHGPML 763
+ L+ +E C HV D + P+ F YSL + P P+L
Sbjct: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVL 600
Query: 764 --DDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYT 821
G + F C E C DL L + L ++M+
Sbjct: 601 RWKKGQKIAQKNQTVFERNC-RSEDCAADLQLQGKL-LLSSMD----------------- 641
Query: 822 LSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIEC 881
+ T+++ + +++ ++ N G++AY ++ + S L F ++ QKE+ I C
Sbjct: 642 ---EKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEM--GISC 696
Query: 882 VNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNERDSTK 940
E K C+V +PF R+K+K F + F+ S S L + A S + ER +
Sbjct: 697 ELLESDFLK--CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESL 754
Query: 941 EDNVAPLRFHLKYEADVLFT---RSSSLSHYEVKPNSSLERYDGIG---PPFSCIFRIQN 994
DN L L +E D T +S + E ++ + D + P + ++ N
Sbjct: 755 HDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYN 814
Query: 995 LGLFPIHGMMMKITIPIATRSGN-RLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDL- 1052
G + G + I+ P SG + +++ + + +C+ N T +E++
Sbjct: 815 TGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIF 874
Query: 1053 -----------RRAPQLNHSNSDVVSINCNIRLVPNQE---INFHLLGN---LWLRSLKA 1095
R+ ++ +CN + +E I+ ++L N L S
Sbjct: 875 HTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSV 934
Query: 1096 LKYKS-MKIMVNAALQRQFHSPFIFREEDPSRQIVFEI--SKQEDWQVPIWIIVGSTLGG 1152
+++ S K+ V+ AL+ I +VFE + + V WII S L G
Sbjct: 935 IQFMSRAKVKVDPALR----VVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVG 990
Query: 1153 LLLLALLVLALWKLGFFRSARRRRE 1177
+L+ LL + LWK+GFFR RR +E
Sbjct: 991 ILIFLLLAVLLWKMGFFR--RRYKE 1013
Score = 64.3 bits (155), Expect = 7e-10
Identities = 53/175 (30%), Positives = 83/175 (47%), Gaps = 29/175 (16%)
Query: 5 RGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLET 64
R L++A ++ P +N+D ++P G +FFGY V +H +W++VGAP
Sbjct: 14 RALLLALVVAGIPA--GAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKAD 71
Query: 65 NGY----QKTGDVYKCPVIHGN----CTKLNLGRVTLSNVS------ERKDNMRLGLSLA 110
+ Y + G V+KC V H N CT+L++ R S E +D+ +G+SLA
Sbjct: 72 SKYSPSVKSPGAVFKCRV-HTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLA 130
Query: 111 TNPK-DNSFLACSPLWSHECGSSYYTT------GMCSRVNSNFRF-SKTVAPALQ 157
PK D LAC+ W + YY G C + SN + +T+ P +
Sbjct: 131 RQPKADGRVLACAHRWK----NIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYE 181
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 203 bits (517), Expect = 7e-52
Identities = 228/870 (26%), Positives = 377/870 (43%), Gaps = 129/870 (14%)
Query: 368 QTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN--HGAYL 425
Q G SS +D +++GA G+ W G++ V + + K F ++ G+YL
Sbjct: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLF-------VYNITTNKYKAFLDKQNQVKFGSYL 251
Query: 426 GYTV-TSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEI 484
GY+V S+ V GAP+ GK +F++ + + L I M+G+++GSYFG+ +
Sbjct: 252 GYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSI-DEKELNILHEMKGKKLGSYFGASV 310
Query: 485 TSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG---TLKDSHSYQNAR 541
+VD++ DG +D LLVGAPM + RE G+V+VY + V N L S Y AR
Sbjct: 311 CAVDLNADGFSD-LLVGAPMQ-STIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-AR 367
Query: 542 FGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGL 601
FG SI ++ D++ D + DV +GAP ED+ GAIYI++G I T QRI +++ L
Sbjct: 368 FGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSL 427
Query: 602 QYFGCSIHGQLDLNEDGLIDLAVGAL--GNAVILWSRPVVQINASLHFEPSKINIFHRDC 659
FG SI GQ+D + +G +D+AVGA +AV+L +RPVV ++ASL P +N DC
Sbjct: 428 SMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC 486
Query: 660 KRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYT---PRAHLDEGG--DR 714
+G + C+ LCF+ + V + YN ++D R PR + G D
Sbjct: 487 VENGWPSVCIDLTLCFS--YKGKEVPGYIV-LFYNMSLDVNRKAESPPRFYFSSNGTSDV 543
Query: 715 FTNRAVLLSSGQELCERIN-FHVLDTADYVKPVTFSVEYSL-----------EDPDHGPM 762
T ++ +SS + C F D D + P+ Y L E P P+
Sbjct: 544 ITG-SIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPI 602
Query: 763 LDD-GWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYT 821
L ++ ++ F C E+C DL + A+ +
Sbjct: 603 LQQKKEKDIMKKTINFARFC-AHENCSADLQVSAK---------------------IGFL 640
Query: 822 LSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIEC 881
+ ++ + + + + +L N G++AY T L++ L F +++ E+ + E
Sbjct: 641 KPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEV 700
Query: 882 VNEERRLQKQVCNVSYPF--FRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDST 939
+ +Q C++ Y + ++ ++F LD S S L I + A ++ E
Sbjct: 701 TDNSGVVQLD-CSIGYIYVDHLSRIDISFLLDVS-SLSRAEEDLSITVHATCENEEEMDN 758
Query: 940 KEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFP 999
+ + + LKYE + H V P S + + P +C+ NL
Sbjct: 759 LKHSRVTVAIPLKYEVKLTV-------HGFVNPTSFVYGSNDENEPETCMVEKMNLTFHV 811
Query: 1000 IH-GMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE---EDLRRA 1055
I+ G M + + N D L N + + T E E+ +R
Sbjct: 812 INTGNSMAPNVSVEIMVPNSFSPQTDKLF-----------NILDVQTTTGECHFENYQRV 860
Query: 1056 PQLNHSNSDVVSINCNIRLVPNQEINF--------HLLGNLW-LRSLKALKYKSMKIMV- 1105
L S + ++ +R + + H L L +++ K S+ I +
Sbjct: 861 CALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLE 920
Query: 1106 ----------NAALQRQFHSPFIFREEDPSRQIVFEISKQED----------WQVP---- 1141
+AL+ + + F E +P V E++K E+ Q P
Sbjct: 921 GRPSILEMDETSALKFEIRATG-FPEPNPR---VIELNKDENVAHVLLEGLHHQRPKRYF 976
Query: 1142 -IWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
I II S L GL++L L+ +WK GFF+
Sbjct: 977 TIVIISSSLLLGLIVLLLISYVMWKAGFFK 1006
Score = 60.1 bits (144), Expect = 1e-08
Identities = 45/152 (29%), Positives = 65/152 (42%), Gaps = 17/152 (11%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAP----LETNGYQKTGDVYKCPV 78
+N+DT + G FGY+V H N+WL+VGAP L G +Y+C +
Sbjct: 34 YNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLANASVINPGAIYRCRI 93
Query: 79 IHG---NCTKLNL----GRVTLSNVSERKDNMRLGLSLATNPKDN-SFLACSPLWS---H 127
C +L L G E +DN LG++L+ P +N S + C W +
Sbjct: 94 GKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFY 153
Query: 128 ECGSSYYTTGMCSRVNSNFR--FSKTVAPALQ 157
+ TG C V + R SK +AP Q
Sbjct: 154 IKNENKLPTGGCYGVPPDLRTELSKRIAPCYQ 185
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 189 bits (481), Expect = 1e-47
Identities = 227/892 (25%), Positives = 371/892 (41%), Gaps = 159/892 (17%)
Query: 368 QTGFSSHVVEDG-VLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN------ 420
Q GFS+ + G V+LG G+Y W G +L T + ESY +PE L N
Sbjct: 206 QGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQE----QIAESY---YPEYLINLVQGQL 258
Query: 421 ---------HGAYLGYTVT-SVVSSRQGRVYVAGAPRFNHT-GKVILFTMHNNRSLTIHQ 469
+YLGY+V S +VAG P+ N T G V + + RSL
Sbjct: 259 QTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGSDIRSL---Y 315
Query: 470 AMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFN---EGR--ERGKVYVYELRQNL 524
G+Q+ SYFG + + D++GDG+ D LLVGAP+ + +GR E G+VYVY
Sbjct: 316 NFSGEQMASYFGYAVAATDVNGDGLDD-LLVGAPLLMDRTPDGRPQEVGRVYVYLQHPAG 374
Query: 525 FVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYIFHGFRGS 583
TL + + RFGSS+ + DL+QD YNDV +GAP + G +++F G G
Sbjct: 375 IEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGG 434
Query: 584 ILKTPKQRITASELATGL-QYFGCSIHGQLDLNEDGLIDLAVGALG--NAVILWSRPVVQ 640
+ P Q + A+ +FG ++ G DL+ +G DL VG+ G AV+ RP+V
Sbjct: 435 LGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVS 494
Query: 641 INASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFT------------PIFLAPHFQTTT 688
+ASL P+ N R C G C+ C + L +Q
Sbjct: 495 ASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIGFTVELQLDWQKQK 554
Query: 689 VGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKP 745
G+R + R+ T T ++ + +E C + ++ + +++ + P
Sbjct: 555 GGVRRALFLASRQAT-----------LTQTLLIQNGAREDCREMKIYLRNESEFRDKLSP 603
Query: 746 VTFSVEYSLED----PDHG--PMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDL 799
+ ++ +SL+ HG P L + + C ED CVPDL L+ +
Sbjct: 604 IHIALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQ 663
Query: 800 PTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGE-NAYSTVLNI 858
D +A L+F +N GE AY L +
Sbjct: 664 NHVY----------LGDKNALNLTFHA------------------QNVGEGGAYEAELRV 695
Query: 859 SQSANLQFASLIQKEDSDGSIEC----VNEERRLQKQVCNVSYPFFRAKAKVAFRLDF-- 912
+ +++ L++ + S+ C VN+ R L VC++ P +A A + L F
Sbjct: 696 TAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLL---VCDLGNP-MKAGASLWGGLRFTV 751
Query: 913 ----EFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSS---- 964
+ K+I + ++ + + +N + +V R ++ +A V S
Sbjct: 752 PHLRDTKKTI---QFDFQILSKNLNN-----SQSDVVSFRLSVEAQAQVTLNGVSKPEAV 803
Query: 965 -LSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLR 1023
+ P ++ + +GP ++ + N G I +++++ P A L R
Sbjct: 804 LFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQQLLYVTR 863
Query: 1024 -DFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINF 1082
L N N G + + + R AP + ++S + C P E F
Sbjct: 864 VTGLNCTTNHPINPKGLELDPEGSLHHQQKREAPSRSSASSGPQILKC-----PEAEC-F 917
Query: 1083 HL---LGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREED-------PSRQIVFEI 1132
L LG L + ++L+ ++ LQR+ H PF + E P R + ++
Sbjct: 918 RLRCELGPLHQQESQSLQL-HFRVWAKTFLQRE-HQPFSLQCEAVYKALKMPYRILPRQL 975
Query: 1133 SKQE--------------DWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
++E + VP+WII+ + L GLLLL LL+ L+KLGFF+
Sbjct: 976 PQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFK 1027
Score = 37.0 bits (84), Expect = 0.11
Identities = 42/152 (27%), Positives = 61/152 (40%), Gaps = 22/152 (14%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQ-QHDISGNKWLVVGAPLETN---GYQKTGDVYKCP- 77
FN+D P V+ G +FFG++V+ + ++VGAP G + G VY CP
Sbjct: 42 FNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYLCPW 101
Query: 78 -VIHGNCTKLNL----GRVTLSNVS--------ERKDNMRLGLSLATNPKDNSFLACSPL 124
CT + R+ S++S E K G ++ + +S LAC+PL
Sbjct: 102 GASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGATVRAH--GSSILACAPL 159
Query: 125 --WSHECGSSYYTTGMCSRVNSNFRFSKTVAP 154
W E G C NF AP
Sbjct: 160 YSWRTEKEPLSDPVGTCYLSTDNFTRILEYAP 191
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 183 bits (464), Expect = 1e-45
Identities = 227/926 (24%), Positives = 388/926 (41%), Gaps = 132/926 (14%)
Query: 338 LKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDG--VLLGAVGAYDWNGAVL 395
++D +D GD F +G + FG Q G ++ +D ++ GA G Y+W G V
Sbjct: 163 IEDDMDG-GDWSFC-DGRLRGHEKFG--SCQQGVAATFTKDFHYIVFGAPGTYNWKGIVR 218
Query: 396 KETSAGKVIPLRESYLKEFPEELKNH------------GAYLGYTVTSV--VSSRQGRVY 441
E + + ++ P E+ +YLG+++ S + S+ +
Sbjct: 219 VEQKNNTFFDM--NIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITF 276
Query: 442 VAGAPRFNHTGKVILFTMH-NNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLV 500
V+GAPR NH+G V+L + L G+ + S FG ++ VD++ DG D++ +
Sbjct: 277 VSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-I 335
Query: 501 GAPMYFN-EGRERGKVYVYELRQNLFV------YNGTLKDSHSYQNARFGSSIASVRDLN 553
GAP YF+ +G G VYVY +Q + NGT KDS FG ++ ++ D+N
Sbjct: 336 GAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGT-KDS------MFGIAVKNIGDIN 388
Query: 554 QDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLD 613
QD Y D+ VGAP +D G ++I+HG I P Q + YFG SI G +D
Sbjct: 389 QDGYPDIAVGAPYDD--LGKVFIYHGSANGINTKPTQVLKGIS-----PYFGYSIAGNMD 441
Query: 614 LNEDGLIDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAF 672
L+ + D+AVG+L ++V ++ SRPV+ I ++ P++I++ + CL
Sbjct: 442 LDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDL-RQKTACGAPSGICLQVK 500
Query: 673 LCFTPIFLAPHFQTTTVGIRYNATMDERR---YTPRAHLDEGGD--RFTNRAVLLSSGQE 727
CF + + + ERR + R G ++T L Q+
Sbjct: 501 SCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQK 560
Query: 728 LCERINFHVLDT-ADYVKPVTFSVEYSLEDPDHG----------PMLDDGWPTTLRVSVP 776
+C + D D ++P+ + +++P P+L+ P T + V
Sbjct: 561 VCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVH 620
Query: 777 FW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTR 835
F GC +D C S+L ++C R+ QD +Y ++ +
Sbjct: 621 FLKEGCGDDNVC--------NSNLKLEYKFC---TREGNQDKFSYLPIQKGVPELVLKDQ 669
Query: 836 QRVAVEATLENR----------GENAYSTVLNISQSANLQFASLIQ-KEDSDGSIECVNE 884
+ +A+E T+ N G++A+ L + L +++ + + + + CV
Sbjct: 670 KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVAN 729
Query: 885 ERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIF-LHHLEIELAAGSDSNERDSTKEDN 943
+ Q C + PF R + V F L ++ F L+I L + SN +DN
Sbjct: 730 QNGSQAD-CELGNPFKR-NSNVTFYLVLSTTEVTFDTPDLDINLKLETTSN------QDN 781
Query: 944 VAPLRFHLKYEADVLFTRSSSLSHYE------VKPNSSLERYDGIGPPFSCIFRIQNLG- 996
+AP+ K ++L + S + V +++ D +G FR+ NLG
Sbjct: 782 LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGK 841
Query: 997 -LFPIHGMMMKITIPIATRSGNRLLKL-------RDFLTDEANTSCNIWGNSTEYRPTPV 1048
L + + I P +G LL L + +T E N N TE +
Sbjct: 842 PLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSL-NLTESHNSRK 900
Query: 1049 EEDL----------------RRAPQLNHS-NSDVVSINCNIRLVPNQE---INFHLLGNL 1088
+ ++ R+ LN S N + V+I C +R + ++ + L +
Sbjct: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST 960
Query: 1089 WLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQ-VPIWIIVG 1147
+L L Y + + + + + R VF + VP WII+
Sbjct: 961 FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV 1020
Query: 1148 STLGGLLLLALLVLALWKLGFFRSAR 1173
+ L G+L+LALLV LWK GFF+ +R
Sbjct: 1021 AILAGILMLALLVFILWKCGFFKRSR 1046
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 181 bits (460), Expect = 3e-45
Identities = 226/927 (24%), Positives = 388/927 (41%), Gaps = 132/927 (14%)
Query: 338 LKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDG--VLLGAVGAYDWNGAVL 395
++D +D GD F +G + FG Q G ++ +D ++ GA G Y+W G V
Sbjct: 163 IEDDMDG-GDWSFC-DGRLRGHEKFG--SCQQGVAATFTKDFHYIVFGAPGTYNWKGIVR 218
Query: 396 KETSAGKVIPLRESYLKEFPEELKNH------------GAYLGYTVTSV--VSSRQGRVY 441
E + + ++ P E+ +YLG+++ S + S+ +
Sbjct: 219 VEQKNNTFFDM--NIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITF 276
Query: 442 VAGAPRFNHTGKVILFTMH-NNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLV 500
V+GAPR NH+G V+L + L G+ + S FG ++ VD++ DG D++ +
Sbjct: 277 VSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-I 335
Query: 501 GAPMYFN-EGRERGKVYVYELRQNLFV------YNGTLKDSHSYQNARFGSSIASVRDLN 553
GAP YF+ +G G VYVY +Q + NGT KDS FG ++ ++ D+N
Sbjct: 336 GAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGT-KDS------MFGIAVKNIGDIN 388
Query: 554 QDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLD 613
QD Y D+ VGAP +D G ++I+HG I P Q + YFG SI G +D
Sbjct: 389 QDGYPDIAVGAPYDD--LGKVFIYHGSANGINTKPTQVLKGIS-----PYFGYSIAGNMD 441
Query: 614 LNEDGLIDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAF 672
L+ + D+AVG+L ++V ++ SRPV+ I ++ P++I++ + CL
Sbjct: 442 LDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDL-RQKTACGAPSGICLQVK 500
Query: 673 LCFTPIFLAPHFQTTTVGIRYNATMDERR---YTPRAHLDEGGD--RFTNRAVLLSSGQE 727
CF + + + ERR + R G ++T L Q+
Sbjct: 501 SCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQK 560
Query: 728 LCERINFHVLDT-ADYVKPVTFSVEYSLEDPDHG----------PMLDDGWPTTLRVSVP 776
+C + D D ++P+ + +++P P+L+ P T + V
Sbjct: 561 VCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVH 620
Query: 777 FW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTR 835
F GC +D C S+L ++C R+ QD +Y ++ +
Sbjct: 621 FLKEGCGDDNVC--------NSNLKLEYKFC---TREGNQDKFSYLPIQKGVPELVLKDQ 669
Query: 836 QRVAVEATLENR----------GENAYSTVLNISQSANLQFASLIQ-KEDSDGSIECVNE 884
+ +A+E T+ N G++A+ L + L +++ + + + + CV
Sbjct: 670 KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVAN 729
Query: 885 ERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIF-LHHLEIELAAGSDSNERDSTKEDN 943
+ Q C + PF R + V F L ++ F L+I L + SN +DN
Sbjct: 730 QNGSQAD-CELGNPFKR-NSNVTFYLVLSTTEVTFDTPDLDINLKLETTSN------QDN 781
Query: 944 VAPLRFHLKYEADVLFTRSSSLSHYE------VKPNSSLERYDGIGPPFSCIFRIQNLG- 996
+AP+ K ++L + S + V +++ D +G FR+ NLG
Sbjct: 782 LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGK 841
Query: 997 -LFPIHGMMMKITIPIATRSGNRLLKL-------RDFLTDEANTSCNIWGNSTEYRPTPV 1048
L + + I P +G LL L + +T E N N TE +
Sbjct: 842 PLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSL-NLTESHNSRK 900
Query: 1049 EEDL----------------RRAPQLNHS-NSDVVSINCNIRLVPNQE---INFHLLGNL 1088
+ ++ R+ LN S N + V+I C +R + ++ + L +
Sbjct: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST 960
Query: 1089 WLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQ-VPIWIIVG 1147
+L L Y + + + + + R VF + VP WII+
Sbjct: 961 FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV 1020
Query: 1148 STLGGLLLLALLVLALWKLGFFRSARR 1174
+ L G+L+LALLV LWK GFF+ ++
Sbjct: 1021 AILAGILMLALLVFILWKCGFFKRNKK 1047
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 172 bits (435), Expect = 2e-42
Identities = 186/703 (26%), Positives = 301/703 (42%), Gaps = 89/703 (12%)
Query: 353 EGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLK 412
E N N M Q G S ++ V GA GAY+W G +I +E L
Sbjct: 183 EMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN-------SYMIQRKEWDLS 235
Query: 413 EF----PEELKNHGAYLGYT--VTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLT 466
E+ PE+ N Y+GYT V S + + V GAPR H G V L + L
Sbjct: 236 EYSYKDPEDQGN--LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLR 293
Query: 467 IHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRE-RGKVYVYELRQNLF 525
Q + G Q+G+YFGS I D++ DG D LLVGAP YF E G +YV+ +
Sbjct: 294 RRQVLEGSQVGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTS 352
Query: 526 VYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSIL 585
H + FG S+AS+ D+NQD + D+ VGAP E G +YI+H +L
Sbjct: 353 FPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLL 410
Query: 586 KTPKQRITASELA-TGLQYFGCSIHGQLDLNEDGLIDLAVGALG-NAVILWSRPVVQI-N 642
+ P+Q I +L GL FG S+ GQ+D++E+ DL VG+L + V+L +RPV+ I +
Sbjct: 411 RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH 470
Query: 643 ASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLA--PHFQTTTVGIRYNATMDER 700
+L P+ ++ +C+ LCF A P+++ + + Y D
Sbjct: 471 KTLVPRPAVLD------PALCTATSCVQVELCFAYNQSAGNPNYR-RNITLAYTLEADRD 523
Query: 701 RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDT-ADYVKPVTFSVEYS------ 753
R PR L G S + C+++ ++D D ++P+ S+ YS
Sbjct: 524 RRPPR--LRFAGSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
Query: 754 ------LEDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQ 807
L D P+L+ V F C D C +L + A E Q
Sbjct: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRA----AFVSEQQQ 637
Query: 808 RVLR-KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQF 866
++ R + ++D LS + T +TR T E GE+A+ +L + L
Sbjct: 638 KLSRLQYSRDVRKLLLSINVT-----NTR-------TSERSGEDAHEALLTLVVPPALLL 685
Query: 867 ASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFE-FSKSIFLHHLEI 925
+S ++ + + E + C + PF R ++ + FE ++ L++
Sbjct: 686 SS-VRPPGACQANETI---------FCELGNPFKR-NQRMELLIAFEVIGVTLHTRDLQV 734
Query: 926 ELAAGSDSNERDSTKEDNVAPL------RFHLKYEADVLFTRSSSLSHYEVKPNSSLERY 979
+L + S+ +DN+ P+ + L+ ++ R S V S ++
Sbjct: 735 QLQLSTSSH------QDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTV 788
Query: 980 DGIGPPFSCIFRIQNL--GLFPIHGMMMKITIPIATRSGNRLL 1020
+ +G P F++ + GL + +++ + P +G LL
Sbjct: 789 EDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLL 831
Score = 44.3 bits (103), Expect = 7e-04
Identities = 18/45 (40%), Positives = 31/45 (68%)
Query: 1131 EISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRR 1175
E+ ++ ++ +W+++ + GLLLL L++L LWK GFF+ AR R
Sbjct: 981 ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTR 1025
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 172 bits (435), Expect = 2e-42
Identities = 186/703 (26%), Positives = 301/703 (42%), Gaps = 89/703 (12%)
Query: 353 EGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLK 412
E N N M Q G S ++ V GA GAY+W G +I +E L
Sbjct: 183 EMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN-------SYMIQRKEWDLS 235
Query: 413 EF----PEELKNHGAYLGYT--VTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLT 466
E+ PE+ N Y+GYT V S + + V GAPR H G V L + L
Sbjct: 236 EYSYKDPEDQGN--LYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLR 293
Query: 467 IHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRE-RGKVYVYELRQNLF 525
Q + G Q+G+YFGS I D++ DG D LLVGAP YF E G +YV+ +
Sbjct: 294 RRQVLEGSQVGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTS 352
Query: 526 VYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSIL 585
H + FG S+AS+ D+NQD + D+ VGAP E G +YI+H +L
Sbjct: 353 FPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLL 410
Query: 586 KTPKQRITASELA-TGLQYFGCSIHGQLDLNEDGLIDLAVGALG-NAVILWSRPVVQI-N 642
+ P+Q I +L GL FG S+ GQ+D++E+ DL VG+L + V+L +RPV+ I +
Sbjct: 411 RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH 470
Query: 643 ASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLA--PHFQTTTVGIRYNATMDER 700
+L P+ ++ +C+ LCF A P+++ + + Y D
Sbjct: 471 KTLVPRPAVLD------PALCTATSCVQVELCFAYNQSAGNPNYR-RNITLAYTLEADRD 523
Query: 701 RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDT-ADYVKPVTFSVEYS------ 753
R PR L G S + C+++ ++D D ++P+ S+ YS
Sbjct: 524 RRPPR--LRFAGSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
Query: 754 ------LEDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQ 807
L D P+L+ V F C D C +L + A E Q
Sbjct: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRA----AFVSEQQQ 637
Query: 808 RVLR-KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQF 866
++ R + ++D LS + T +TR T E GE+A+ +L + L
Sbjct: 638 KLSRLQYSRDVRKLLLSINVT-----NTR-------TSERSGEDAHEALLTLVVPPALLL 685
Query: 867 ASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFE-FSKSIFLHHLEI 925
+S ++ + + E + C + PF R ++ + FE ++ L++
Sbjct: 686 SS-VRPPGACQANETI---------FCELGNPFKR-NQRMELLIAFEVIGVTLHTRDLQV 734
Query: 926 ELAAGSDSNERDSTKEDNVAPL------RFHLKYEADVLFTRSSSLSHYEVKPNSSLERY 979
+L + S+ +DN+ P+ + L+ ++ R S V S ++
Sbjct: 735 QLQLSTSSH------QDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTV 788
Query: 980 DGIGPPFSCIFRIQNL--GLFPIHGMMMKITIPIATRSGNRLL 1020
+ +G P F++ + GL + +++ + P +G LL
Sbjct: 789 EDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLL 831
Score = 38.5 bits (88), Expect = 0.038
Identities = 15/43 (34%), Positives = 28/43 (65%)
Query: 1131 EISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173
E+ ++ ++ +W+++ + GLLLL L++L LWK FF+ R
Sbjct: 981 ELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTR 1023
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 171 bits (434), Expect = 3e-42
Identities = 211/892 (23%), Positives = 359/892 (40%), Gaps = 120/892 (13%)
Query: 363 GLEMSQTGFSSHVVE-DGVLLGAVGAYDWNGAVLKETSAGKVIPLRES-YLKEFPEELKN 420
G Q GFS + D VLLG G++ W G ++ + A V + Y ++ +L
Sbjct: 135 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 194
Query: 421 HGA-------YLGYTVTSVVSSRQG-RVYVAGAPRFNHT-GKVILFTMHNNRSLTIHQAM 471
A YLGY+V + G +V+G PR T G V ++ N SL
Sbjct: 195 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 251
Query: 472 RGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG-- 529
G+Q+ +YFG + + DI+GD DV +GAP++ + G + V ++ +L +G
Sbjct: 252 TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDF 310
Query: 530 -TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYIFHGFRGSILKT 587
T K + ARFGS+IA + DL+QD +ND+ + AP ++ G +YIF+G +
Sbjct: 311 QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 370
Query: 588 PKQRITASELATGL-QYFGCSIHGQLDLNEDGLIDLAVGALG--NAVILWSRPVVQINAS 644
P Q + A + FG S+ G D++++G DL VGA G A++ +RPV+ +NA
Sbjct: 371 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 430
Query: 645 LHFEPSKINIFHRDCKRSGR--DATCLAAFLCFTP--IFLAPHFQTTTVGIRYNATMDER 700
L PS +N ++ C G +C C + P V + + +
Sbjct: 431 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 490
Query: 701 RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKPVTFSVEYSL--- 754
L + + G CE + ++ D +++ + P+T +EY L
Sbjct: 491 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 550
Query: 755 ---EDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLR 811
+ P+L+ P + C ED C P L + SD
Sbjct: 551 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD------------- 597
Query: 812 KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQ 871
++I + + V+A +N+GE AY L +S F +++
Sbjct: 598 -------------QKKIYIGDDNPLTLIVKA--QNQGEGAYEAELIVSIPLQADFIGVVR 642
Query: 872 KEDSDGSIECV-NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAG 930
++ + C E + ++ VC++ P KA FS E++ +
Sbjct: 643 NNEALARLSCAFKTENQTRQVVCDLGNPM---KAGTQLLAGLRFSVH---QQSEMDTSVK 696
Query: 931 SDSNERDSTKEDNVAPLRFH---LKYEADVLFTRSSSLSH-------YEVKPNSSLERYD 980
D + S D V+P+ H L A V SS H +E K N E +
Sbjct: 697 FDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE--E 754
Query: 981 GIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNS 1040
+GP I+ ++N G M+ + P + L L + N + ++ N
Sbjct: 755 DVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINP 814
Query: 1041 TEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKAL---- 1096
+ + ++ + D + ++ L E + H LG + LK +
Sbjct: 815 LRIKISSLQTTEKNDTVAGQGERDHLITKRDLAL---SEGDIHTLGCGVAQCLKIVCQVG 871
Query: 1097 ---KYKSMKIMVNAAL--------QRQFHSPFIFRE------EDPSRQIVFE-------I 1132
+ KS + V + L + Q HS + E P + + E +
Sbjct: 872 RLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLV 931
Query: 1133 SKQEDW-------QVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRRE 1177
+ W VP+W+I+ + L GLLLLA+LV ++++GFF+ R +E
Sbjct: 932 TTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQE 983
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 171 bits (434), Expect = 3e-42
Identities = 211/892 (23%), Positives = 359/892 (40%), Gaps = 120/892 (13%)
Query: 363 GLEMSQTGFSSHVVE-DGVLLGAVGAYDWNGAVLKETSAGKVIPLRES-YLKEFPEELKN 420
G Q GFS + D VLLG G++ W G ++ + A V + Y ++ +L
Sbjct: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240
Query: 421 HGA-------YLGYTVTSVVSSRQG-RVYVAGAPRFNHT-GKVILFTMHNNRSLTIHQAM 471
A YLGY+V + G +V+G PR T G V ++ N SL
Sbjct: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 297
Query: 472 RGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG-- 529
G+Q+ +YFG + + DI+GD DV +GAP++ + G + V ++ +L +G
Sbjct: 298 TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDF 356
Query: 530 -TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYIFHGFRGSILKT 587
T K + ARFGS+IA + DL+QD +ND+ + AP ++ G +YIF+G +
Sbjct: 357 QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 416
Query: 588 PKQRITASELATGL-QYFGCSIHGQLDLNEDGLIDLAVGALG--NAVILWSRPVVQINAS 644
P Q + A + FG S+ G D++++G DL VGA G A++ +RPV+ +NA
Sbjct: 417 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476
Query: 645 LHFEPSKINIFHRDCKRSGR--DATCLAAFLCFTP--IFLAPHFQTTTVGIRYNATMDER 700
L PS +N ++ C G +C C + P V + + +
Sbjct: 477 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536
Query: 701 RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKPVTFSVEYSL--- 754
L + + G CE + ++ D +++ + P+T +EY L
Sbjct: 537 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 596
Query: 755 ---EDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLR 811
+ P+L+ P + C ED C P L + SD
Sbjct: 597 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD------------- 643
Query: 812 KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQ 871
++I + + V+A +N+GE AY L +S F +++
Sbjct: 644 -------------QKKIYIGDDNPLTLIVKA--QNQGEGAYEAELIVSIPLQADFIGVVR 688
Query: 872 KEDSDGSIECV-NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAG 930
++ + C E + ++ VC++ P KA FS E++ +
Sbjct: 689 NNEALARLSCAFKTENQTRQVVCDLGNPM---KAGTQLLAGLRFSVH---QQSEMDTSVK 742
Query: 931 SDSNERDSTKEDNVAPLRFH---LKYEADVLFTRSSSLSH-------YEVKPNSSLERYD 980
D + S D V+P+ H L A V SS H +E K N E +
Sbjct: 743 FDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE--E 800
Query: 981 GIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNS 1040
+GP I+ ++N G M+ + P + L L + N + ++ N
Sbjct: 801 DVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINP 860
Query: 1041 TEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKAL---- 1096
+ + ++ + D + ++ L E + H LG + LK +
Sbjct: 861 LRIKISSLQTTEKNDTVAGQGERDHLITKRDLAL---SEGDIHTLGCGVAQCLKIVCQVG 917
Query: 1097 ---KYKSMKIMVNAAL--------QRQFHSPFIFRE------EDPSRQIVFE-------I 1132
+ KS + V + L + Q HS + E P + + E +
Sbjct: 918 RLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLV 977
Query: 1133 SKQEDW-------QVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRRE 1177
+ W VP+W+I+ + L GLLLLA+LV ++++GFF+ R +E
Sbjct: 978 TTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQE 1029
Score = 35.8 bits (81), Expect = 0.25
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 16/149 (10%)
Query: 4 PRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQ--QHDISGNKWLVVGAP 61
PRGL + + L P FN+D P G ++FG+ V S +L+VGAP
Sbjct: 13 PRGLPLLLSGLLLP-LCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP 71
Query: 62 LETN---GYQKTGDVYKCP-VIHGNCTKLNLGRV-----TLSNVSERKDNMRLGLSLATN 112
G + G V KC C + + E K + G S+ +
Sbjct: 72 KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS- 130
Query: 113 PKDNSFLACSPL--WSHECGSSYYTTGMC 139
K + LAC+PL W E G C
Sbjct: 131 -KQDKILACAPLYHWRTEMKQEREPVGTC 158
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 167 bits (422), Expect = 7e-41
Identities = 210/907 (23%), Positives = 372/907 (41%), Gaps = 125/907 (13%)
Query: 356 NKNETSFGLEMSQTGFSSHVVEDG-VLLGAVGAYDWNGAVLKETSAGKVIPLR-ESYLKE 413
N N G Q GFS ++G +++G G++ W G V+ + A + + L++
Sbjct: 189 NSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRK 248
Query: 414 FPEELKNHGA-------YLGYTVTS-VVSSRQGRVYVAGAPR-FNHTGKVILFTMHNNRS 464
E + A YLGY+V + + + VAG PR + G V + N+
Sbjct: 249 LAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII---NSTD 305
Query: 465 LTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYF-----NEGRERGKVYVY- 518
+T Q G+Q+ SYFG + D++ DG+ DVL VGAP++ + RE G++Y+Y
Sbjct: 306 MTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYL 364
Query: 519 ELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLE-DNHAGAIYIF 577
++ LF L + ++ RFGS++A + DLNQD YND+ +G P + G + I+
Sbjct: 365 QVSSLLFRDPQILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIY 422
Query: 578 HGFRGSILKTPKQRITASELATGL-QYFGCSIHGQLDLNEDGLIDLAVGAL--GNAVILW 634
+G + + P Q + + + FG ++ G D++++ DL VGA G +
Sbjct: 423 NGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYR 482
Query: 635 SRPVVQINASLHFEPSKINIFHRDCK--RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIR 692
+RPVV ++A L P IN+ ++ C+ S A C + +C + + T+ +
Sbjct: 483 ARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCAS---VTGQSIANTIVLM 539
Query: 693 YNATMDERR----YTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKP 745
+D + LD V+ C+ ++ D ++ + P
Sbjct: 540 AEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSP 599
Query: 746 VTFSVEYSLEDP------DHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDL 799
+ S+ YSL++ + P+L+ + C ED CVPDL L AR D
Sbjct: 600 INISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPD- 658
Query: 800 PTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNIS 859
V I + + + A N GE AY L +
Sbjct: 659 -------------------------KHQVIIGDENHLMLIINA--RNEGEGAYEAELFVM 691
Query: 860 QSANLQFASLIQKEDSDGSIECVNEERRLQKQ-VCNVSYPFFRAKAKVAFRLDFEFSKSI 918
+ + + + C + + + VC++ P + + L F+
Sbjct: 692 IPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMV---SGTNYSLGLRFA--- 745
Query: 919 FLHHLE-IELAAGSDSNERDSTKED---NVAPLRFHLKYEADVLFTRSSS-----LSHYE 969
+ LE ++ D R S K++ N L+ ++ A V S L +
Sbjct: 746 -VPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHN 804
Query: 970 VKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRL----LKLRDF 1025
+P + + +GP I+ + N+G I ++++ P + R L ++
Sbjct: 805 WEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGP 864
Query: 1026 LTDEANTSCN------------------IWGNST-----EYRPTPVEEDLRRAPQ--LNH 1060
L + N + N NST R V E R++P LN
Sbjct: 865 LQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNC 924
Query: 1061 SNSDVVSINCNI-RLVPNQEINFHLLGNLWLRSLKALKYK--SMKIMVNAALQRQFHSPF 1117
+N + + I+C + RL + + LW + K ++ +V+ +++ ++
Sbjct: 925 TNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQ 984
Query: 1118 IFREEDPSRQI---VFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARR 1174
+ + S I V + + +P+W+I+ + L GLL+LA+L LALWK GFF AR
Sbjct: 985 PAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARP 1044
Query: 1175 RREPGLD 1181
+E D
Sbjct: 1045 PQEDMTD 1051
Score = 36.2 bits (82), Expect = 0.19
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 10 AWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQH-DISGNKWLVVGAPLETNGYQ 68
A + LW FN+D K V G + ++FGY V H + ++VGAP + N Q
Sbjct: 26 ALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAP-KANTSQ 84
Query: 69 ----KTGDVYKCP 77
+ G VY CP
Sbjct: 85 PDIVEGGAVYYCP 97
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 161 bits (407), Expect = 4e-39
Identities = 193/823 (23%), Positives = 332/823 (40%), Gaps = 111/823 (13%)
Query: 423 AYLGYTVTSVVSSRQG-RVYVAGAPRFNHT-GKVILFTMHNNRSLTIHQAMRGQQIGSYF 480
+YLGY+V + G +V+G PR T G V ++ N SL G+Q+ +YF
Sbjct: 214 SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNFTGEQMAAYF 270
Query: 481 GSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG---TLKDSHSY 537
G + + DI+GD DV +GAP++ + G + V ++ +L +G T K +
Sbjct: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
Query: 538 QNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYIFHGFRGSILKTPKQRITASE 596
ARFGS+IA + DL+QD +ND+ + AP ++ G +YIF+G + P Q +
Sbjct: 330 VFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQW 389
Query: 597 LATGL-QYFGCSIHGQLDLNEDGLIDLAVGALG--NAVILWSRPVVQINASLHFEPSKIN 653
A + FG S+ G D++++G DL VGA G A++ +RPV+ +NA L PS +N
Sbjct: 390 AARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILN 449
Query: 654 IFHRDCKRSGR--DATCLAAFLCFTP--IFLAPHFQTTTVGIRYNATMDERRYTPRAHLD 709
++ C G +C C + P V + + + L
Sbjct: 450 QDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLY 509
Query: 710 EGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKPVTFSVEYSL------EDPDHG 760
+ + G CE + ++ D +++ + P+T +EY L +
Sbjct: 510 SRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQ 569
Query: 761 PMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAY 820
P+L+ P + C ED C P L + SD
Sbjct: 570 PILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD---------------------- 607
Query: 821 TLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIE 880
++I + + V+A +N+GE AY L +S F +++ ++ +
Sbjct: 608 ----QKKIYIGDDNPLTLIVKA--QNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLS 661
Query: 881 CV-NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDST 939
C E + ++ VC++ P KA FS E++ + D + S
Sbjct: 662 CAFKTENQTRQVVCDLGNPM---KAGTQLLAGLRFSVH---QQSEMDTSVKFDLQIQSSN 715
Query: 940 KEDNVAPLRFH---LKYEADVLFTRSSSLSH-------YEVKPNSSLERYDGIGPPFSCI 989
D V+P+ H L A V SS H +E K N E + +GP I
Sbjct: 716 LFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE--EDVGPVVQHI 773
Query: 990 FRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE 1049
+ ++N G M+ + P + L L + N + ++ N + + ++
Sbjct: 774 YELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQ 833
Query: 1050 EDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKAL-------KYKSMK 1102
+ D + ++ L E + H LG + LK + + KS
Sbjct: 834 TTEKNDTVAGQGERDHLITKRDLAL---SEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAI 890
Query: 1103 IMVNAAL--------QRQFHSPFIFRE------EDPSRQIVFE-------ISKQEDW--- 1138
+ V + L + Q HS + E P + + E ++ W
Sbjct: 891 LYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQ 950
Query: 1139 ----QVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRRE 1177
VP+W+I+ + L GLLLLA+LV ++++GFF+ R +E
Sbjct: 951 PAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQE 993
Score = 35.8 bits (81), Expect = 0.25
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 16/149 (10%)
Query: 4 PRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQ--QHDISGNKWLVVGAP 61
PRGL + + L P FN+D P G ++FG+ V S +L+VGAP
Sbjct: 13 PRGLPLLLSGLLLP-LCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP 71
Query: 62 LETN---GYQKTGDVYKCP-VIHGNCTKLNLGRV-----TLSNVSERKDNMRLGLSLATN 112
G + G V KC C + + E K + G S+ +
Sbjct: 72 KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS- 130
Query: 113 PKDNSFLACSPL--WSHECGSSYYTTGMC 139
K + LAC+PL W E G C
Sbjct: 131 -KQDKILACAPLYHWRTEMKQEREPVGTC 158
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 158 bits (399), Expect = 3e-38
Identities = 167/659 (25%), Positives = 287/659 (43%), Gaps = 81/659 (12%)
Query: 330 FNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYD 389
F ++ + A++D +D G+ F EG + FG T + +L GA G Y+
Sbjct: 67 FVLSQDLAIRDELDG-GEWKFC-EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYN 124
Query: 390 WNGAVLKETSAGKVIPLRESYLKEFPEELKNH------------GAYLGYTVTSV--VSS 435
W G E A L ++L + P E +Y G+++ S +
Sbjct: 125 WKGTARVELCAQGSADL--AHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVR 182
Query: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
+ +VAGAPR NH G V++ + L + G+++ S FG + D++ DG
Sbjct: 183 AEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWP 242
Query: 496 DVLLVGAPMYFNEGRE-RGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQ 554
D L+VGAP +F E G VYVY + + L+ S ++ FG S+A + DLNQ
Sbjct: 243 D-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGS-PDSMFGISLAVLGDLNQ 300
Query: 555 DSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDL 614
D + D+ VGAP + + G ++I+HG ++ P Q + A G++ FG S+ G LD+
Sbjct: 301 DGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGE--AVGIKSFGYSLSGSLDM 356
Query: 615 NEDGLIDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFL 673
+ + DL VG+L + +L+ +RP++ ++ + P I++ +C +G + C+ +
Sbjct: 357 DGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRV 414
Query: 674 CFTPIFLAPHFQTTTVGIRYNATMDE----RRYTPRA-----HLDEGGDRFTNRAVLLSS 724
CF+ I P + TV + Y D R PR +L+E + + L
Sbjct: 415 CFSYI-AVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQ 473
Query: 725 GQELCERINFHVLDTA-DYVKPVTFSVEYSLED------------PDHGPMLDDGWPTTL 771
+C F + + D ++ + ++ YSL+ P P+L+ P+T
Sbjct: 474 HDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQ 533
Query: 772 RVSVPFW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFD---TT 827
R + F GC ED+ C +L L +C RV D L D TT
Sbjct: 534 RAEIHFLKQGCGEDKICQSNLQL-------VRARFCTRV-----SDTEFQPLPMDVDGTT 581
Query: 828 VFIIESTRQRVAVEATLEN----------RGENAYSTVLNISQSANLQFASLIQKEDSDG 877
S + + +E + N G++A+ L + +L ++ + + ++
Sbjct: 582 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 641
Query: 878 SIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNE 935
+ C++ E + C + P R A+V F L S SI LE+EL + S +
Sbjct: 642 PL-CLSNENASHVE-CELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQ 697
Score = 48.1 bits (113), Expect = 5e-05
Identities = 21/34 (61%), Positives = 28/34 (82%)
Query: 1140 VPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173
VP W+I+ + L GLL+LALLVL LWK+GFF+ A+
Sbjct: 943 VPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 976
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 158 bits (399), Expect = 3e-38
Identities = 167/659 (25%), Positives = 287/659 (43%), Gaps = 81/659 (12%)
Query: 330 FNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYD 389
F ++ + A++D +D G+ F EG + FG T + +L GA G Y+
Sbjct: 164 FVLSQDLAIRDELDG-GEWKFC-EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYN 221
Query: 390 WNGAVLKETSAGKVIPLRESYLKEFPEELKNH------------GAYLGYTVTSV--VSS 435
W G E A L ++L + P E +Y G+++ S +
Sbjct: 222 WKGTARVELCAQGSADL--AHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVR 279
Query: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
+ +VAGAPR NH G V++ + L + G+++ S FG + D++ DG
Sbjct: 280 AEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWP 339
Query: 496 DVLLVGAPMYFNEGRE-RGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQ 554
D L+VGAP +F E G VYVY + + L+ S ++ FG S+A + DLNQ
Sbjct: 340 D-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGS-PDSMFGISLAVLGDLNQ 397
Query: 555 DSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDL 614
D + D+ VGAP + + G ++I+HG ++ P Q + A G++ FG S+ G LD+
Sbjct: 398 DGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGE--AVGIKSFGYSLSGSLDM 453
Query: 615 NEDGLIDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFL 673
+ + DL VG+L + +L+ +RP++ ++ + P I++ +C +G + C+ +
Sbjct: 454 DGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRV 511
Query: 674 CFTPIFLAPHFQTTTVGIRYNATMDE----RRYTPRA-----HLDEGGDRFTNRAVLLSS 724
CF+ I P + TV + Y D R PR +L+E + + L
Sbjct: 512 CFSYI-AVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQ 570
Query: 725 GQELCERINFHVLDTA-DYVKPVTFSVEYSLED------------PDHGPMLDDGWPTTL 771
+C F + + D ++ + ++ YSL+ P P+L+ P+T
Sbjct: 571 HDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQ 630
Query: 772 RVSVPFW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFD---TT 827
R + F GC ED+ C +L L +C RV D L D TT
Sbjct: 631 RAEIHFLKQGCGEDKICQSNLQL-------VRARFCTRV-----SDTEFQPLPMDVDGTT 678
Query: 828 VFIIESTRQRVAVEATLEN----------RGENAYSTVLNISQSANLQFASLIQKEDSDG 877
S + + +E + N G++A+ L + +L ++ + + ++
Sbjct: 679 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 738
Query: 878 SIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNE 935
+ C++ E + C + P R A+V F L S SI LE+EL + S +
Sbjct: 739 PL-CLSNENASHVE-CELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQ 794
Score = 48.1 bits (113), Expect = 5e-05
Identities = 21/34 (61%), Positives = 28/34 (82%)
Query: 1140 VPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173
VP W+I+ + L GLL+LALLVL LWK+GFF+ A+
Sbjct: 1040 VPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1073
Score = 36.6 bits (83), Expect = 0.15
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQH---DISGNKWLVVGAP--LETNGYQ--KTGDVYK 75
FN+D G + FG++V H WL+VGAP L G Q +TG ++
Sbjct: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
Query: 76 CPVI--HGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACS 122
CP+ +C ++++ + E K+N LG+S+ + + C+
Sbjct: 94 CPLSLEETDCYRVDIDQ-GADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 156 bits (395), Expect = 1e-37
Identities = 168/654 (25%), Positives = 288/654 (44%), Gaps = 75/654 (11%)
Query: 330 FNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYD 389
F ++ + A++D +D G+ F EG + FG T + +L GA G Y+
Sbjct: 164 FVLSQDLAIRDELDG-GEWKFC-EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYN 221
Query: 390 WNGAVLKETSAGKVIPLRESYLKEFPEELKNHGA-------YLGYTVTSV--VSSRQGRV 440
W G +L T+ P + Y P + A YLG+++ S + +
Sbjct: 222 WKG-LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELS 280
Query: 441 YVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLV 500
+VAGAPR NH G V++ + L + G+++ S FG + D++ DG D L+V
Sbjct: 281 FVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIV 339
Query: 501 GAPMYFNEGRE-RGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYND 559
GAP +F E G VYVY + + L+ S ++ FG S+A + DLNQD + D
Sbjct: 340 GAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGS-PDSMFGISLAVLGDLNQDGFPD 398
Query: 560 VVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGL 619
+ VGAP + + G ++I+HG ++ P Q + A G++ FG S+ G LD++ +
Sbjct: 399 IAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGE--AVGIKSFGYSLSGSLDMDGNQY 454
Query: 620 IDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPI 678
DL VG+L + +L+ +RP++ ++ + P I++ +C +G + C+ +CF+ I
Sbjct: 455 PDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYI 512
Query: 679 FLAPHFQTTTVGIRYNATMDE----RRYTPRA-----HLDEGGDRFTNRAVLLSSGQELC 729
P + TV + Y D R PR +L+E + + L +C
Sbjct: 513 -AVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVC 571
Query: 730 ERINFHVLDTA-DYVKPVTFSVEYSLED------------PDHGPMLDDGWPTTLRVSVP 776
F + + D ++ + ++ YSL+ P P+L+ P+T R +
Sbjct: 572 GDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIH 631
Query: 777 FW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFD---TTVFIIE 832
F GC ED+ C +L L +C RV D L D TT
Sbjct: 632 FLKQGCGEDKICQSNLQL-------VRARFCTRV-----SDTEFQPLPMDVDGTTALFAL 679
Query: 833 STRQRVAVEATLEN----------RGENAYSTVLNISQSANLQFASLIQKEDSDGSIECV 882
S + + +E + N G++A+ L + +L ++ + + ++ + C+
Sbjct: 680 SGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL-CL 738
Query: 883 NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNE 935
+ E + C + P R A+V F L S SI LE+EL + S +
Sbjct: 739 SNENASHVE-CELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQ 790
Score = 48.1 bits (113), Expect = 5e-05
Identities = 21/34 (61%), Positives = 28/34 (82%)
Query: 1140 VPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173
VP W+I+ + L GLL+LALLVL LWK+GFF+ A+
Sbjct: 1036 VPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1069
Score = 36.6 bits (83), Expect = 0.15
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 23 FNMDTRKPRVIPGSRTAFFGYTVQQH---DISGNKWLVVGAP--LETNGYQ--KTGDVYK 75
FN+D G + FG++V H WL+VGAP L G Q +TG ++
Sbjct: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
Query: 76 CPVI--HGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACS 122
CP+ +C ++++ + E K+N LG+S+ + + C+
Sbjct: 94 CPLSLEETDCYRVDIDQ-GADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 142 bits (359), Expect = 1e-33
Identities = 212/899 (23%), Positives = 353/899 (39%), Gaps = 140/899 (15%)
Query: 357 KNETSFGLEMSQTGFSSHVVEDGVL-LGAVGAYDWNGAVLKETSAGKVIPLRESYL---- 411
+N+ S+ + GFSS V + G L LGA G Y + G + + A R L
Sbjct: 188 ENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHV 247
Query: 412 --KEFPEELKNHGAYLGYTVTSV-VSSRQGRV----YVAGAPRFNHT-GKVILFTMHNNR 463
+ + N + GY SV V G + YV GAP ++ T G V + + R
Sbjct: 248 SSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQR 307
Query: 464 SLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRER-----GKVYVY 518
+H+ +RG+Q+ SYFG + D++GDG D LLVGAP+Y +R G+VY++
Sbjct: 308 ---LHR-LRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLF 362
Query: 519 ELRQNLFVYNG-TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYI 576
+ +L + + RFGS+IA + DL++D YND+ V AP + G + +
Sbjct: 363 LQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLV 422
Query: 577 FHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALG-NAVILW- 634
F G + P Q + S TG FG S+ G +D++++G DL VGA G N V ++
Sbjct: 423 FLGQSEGLRSRPSQ-VLDSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480
Query: 635 SRPVVQINASLHFEPSKINIFHRDC--KRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIR 692
++PVV+ + L + S +N + C ++ +C +C VG
Sbjct: 481 AQPVVKASVQLLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMC--------------VGAT 525
Query: 693 YNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQ--------------ELCERINFHVLD 738
+ + LD R R +LL S Q +C + D
Sbjct: 526 GHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRD 585
Query: 739 TADY---VKPVTFSVEYSLEDPDHG--PMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVL 793
AD+ + P+ S+ SL + G P + T ++ C ED+ CVP L L
Sbjct: 586 EADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQL 645
Query: 794 DARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYS 853
A + VL ++ N GE AY
Sbjct: 646 TASVTGSPLLVGADNVLE----------------------------LQMDAANEGEGAYE 677
Query: 854 TVLNISQSANLQFASLIQKEDSDGSIEC-VNEERRLQKQVCNVSYPFFR-AKAKVAFRLD 911
L + + + + + C +E + +C + P + A+ +A +
Sbjct: 678 AELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVS 737
Query: 912 F----EFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSS---S 964
E +S+ +L S +++ ++K + L ++ EA V +S S
Sbjct: 738 VGNLEEAGESV-----SFQLQIRSKNSQNPNSK---IVLLDVPVRAEAQVELRGNSFPAS 789
Query: 965 LSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL---- 1020
L + D GP + + N G ++G+ + I +P ++ + L
Sbjct: 790 LVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDI 849
Query: 1021 ----KLRDFLTDEANTSCNIWG----NSTEYRPTPVEEDLRR----APQLNHSNSDVVSI 1068
L+ F N WG + + P + D R+ P+ D V +
Sbjct: 850 QPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLV 909
Query: 1069 NCNI-----------RLVPNQEINFHLLGNLWLRSLKALKYKSMKIMVNA---ALQRQFH 1114
+C+ + Q +L LWL SL + +A +
Sbjct: 910 SCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYA 969
Query: 1115 SPFIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173
P + ++ + E+ +PIW ++ LGGLLLL +LVLA+WK+GFF+ R
Sbjct: 970 VPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 98.2 bits (243), Expect = 4e-20
Identities = 71/210 (33%), Positives = 116/210 (55%), Gaps = 18/210 (8%)
Query: 164 DIVIVLDGSNSI--YPWVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRS 221
DIV+++DGS SI + V+ F+ I++ F IGP ++Q+ + QY D E+ LN +R
Sbjct: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 94
Query: 222 VKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKGGRKGAKKVMIVITDGESHDSPD 279
K +++A +++ +GG T T + F R + F Q G R A+K+ ++ITDG+S D D
Sbjct: 95 KKSLLQAVANLPYKGG-NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQD--D 151
Query: 280 LEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALK 339
+E ++ + + V +A+ G N + E+K IA+DPDD H +NV D +L
Sbjct: 152 VEAPSKKLKDEGVELFAI---GIKNADEV-------ELKMIATDPDDTHAYNVADFESLS 201
Query: 340 DIVDALGDRIF-SLEGTNKNETSFGLEMSQ 368
IVD L + S++G E L +S+
Sbjct: 202 RIVDDLTINLCNSVKGPGDLEAPSNLVISE 231
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/201 (33%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 151 TVAPALQRCQ-TYMDIVIVLDGSNSIYP--WVEVQHFLINILKKF-YIGPGQIQVGVVQY 206
T+ PA C+ DIV + D S SI + +V F+ N + F I P IQV VQY
Sbjct: 1145 TIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQY 1204
Query: 207 GEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSE--AFQKGGRKGAKK 264
++V EF LN Y + A +I RGG TRT + F + + ++ G RK K
Sbjct: 1205 SDEVKSEFKLNTYNDKALALGALQNIRYRGG-NTRTGKALTFIKEKVLTWESGMRKNVPK 1263
Query: 265 VMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDP 324
V++V+TDG S D ++ Q +V VA + Y NE+ IAS P
Sbjct: 1264 VLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDY------------NELANIASKP 1311
Query: 325 DDKHFFNVTDEAALKDIVDAL 345
++H F V D + + I D L
Sbjct: 1312 SERHVFIVDDFESFEKIEDNL 1332
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 98.2 bits (243), Expect = 4e-20
Identities = 71/210 (33%), Positives = 116/210 (55%), Gaps = 18/210 (8%)
Query: 164 DIVIVLDGSNSI--YPWVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRS 221
DIV+++DGS SI + V+ F+ I++ F IGP ++Q+ + QY D E+ LN +R
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 222 VKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKGGRKGAKKVMIVITDGESHDSPD 279
K +++A +++ +GG T T + F R + F Q G R A+K+ ++ITDG+S D D
Sbjct: 1259 KKSLLQAVANLPYKGG-NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQD--D 1315
Query: 280 LEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALK 339
+E ++ + + V +A+ G N + E+K IA+DPDD H +NV D +L
Sbjct: 1316 VEAPSKKLKDEGVELFAI---GIKNADEV-------ELKMIATDPDDTHAYNVADFESLS 1365
Query: 340 DIVDALGDRIF-SLEGTNKNETSFGLEMSQ 368
IVD L + S++G E L +S+
Sbjct: 1366 RIVDDLTINLCNSVKGPGDLEAPSNLVISE 1395
Score = 89.7 bits (221), Expect = 1e-17
Identities = 63/182 (34%), Positives = 95/182 (52%), Gaps = 17/182 (9%)
Query: 164 DIVIVLDGSNSI--YPWVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRS 221
DIV ++DGS SI +V+V+ FL ++K F I P ++Q+ +VQY D EF L +
Sbjct: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTK 499
Query: 222 VKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKGGRKGAKKVMIVITDGESHDSPD 279
V+D++EA + RGG+ T T + + R + F KG R KVMI+ITDG+S D+
Sbjct: 500 VEDIIEAINTFPYRGGS-TNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDA-- 556
Query: 280 LEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALK 339
+ +V +AV V + +E++ IAS P + H F V D A +
Sbjct: 557 FRDPAIKLRNSDVEIFAVGV----------KDAVRSELEAIASPPAETHVFTVEDFDAFQ 606
Query: 340 DI 341
I
Sbjct: 607 RI 608
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/201 (33%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 151 TVAPALQRCQ-TYMDIVIVLDGSNSIYP--WVEVQHFLINILKKF-YIGPGQIQVGVVQY 206
T+ PA C+ DIV + D S SI + +V F+ N + F I P IQV VQY
Sbjct: 2309 TIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQY 2368
Query: 207 GEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSE--AFQKGGRKGAKK 264
++V EF LN Y + A +I RGG TRT + F + + ++ G RK K
Sbjct: 2369 SDEVKSEFKLNTYNDKALALGALQNIRYRGG-NTRTGKALTFIKEKVLTWESGMRKNVPK 2427
Query: 265 VMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDP 324
V++V+TDG S D ++ Q +V VA + Y NE+ IAS P
Sbjct: 2428 VLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDY------------NELANIASKP 2475
Query: 325 DDKHFFNVTDEAALKDIVDAL 345
++H F V D + + I D L
Sbjct: 2476 SERHVFIVDDFESFEKIEDNL 2496
Score = 78.6 bits (192), Expect = 3e-14
Identities = 67/202 (33%), Positives = 98/202 (48%), Gaps = 19/202 (9%)
Query: 156 LQRCQT--YMDIVIVLDGSNSI--YPWVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVV 211
+Q+C + D+V ++DGS S+ + + F+ ++ F IG + +VGVVQY D
Sbjct: 130 IQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTR 189
Query: 212 HEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQK--GGRKGAKKVMIVI 269
EF+LN Y +++ A I +GG T T I++ F + G R G KV I+I
Sbjct: 190 TEFNLNQYYQRDELLAAIKKIPYKGG-NTMTGDAIDYLVKNTFTESAGARVGFPKVAIII 248
Query: 270 TDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHF 329
TDG+S D E I E NV V V GI E+K IAS P H
Sbjct: 249 TDGKSQD----EVEIPARELRNV---GVEVFSL----GIKAAD-AKELKQIASTPSLNHV 296
Query: 330 FNVTDEAALKDIVDALGDRIFS 351
FNV + A+ DI + + ++ S
Sbjct: 297 FNVANFDAIVDIQNEIISQVCS 318
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 94.4 bits (233), Expect = 6e-19
Identities = 64/192 (33%), Positives = 102/192 (53%), Gaps = 17/192 (8%)
Query: 159 CQT--YMDIVIVLDGSNSI--YPWVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEF 214
CQT DIVI++DGS SI + + V+HFL N++ F +G + ++G+ QY D E+
Sbjct: 151 CQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEW 210
Query: 215 HLNDYRSVKDVVEAASHIEQRGG-TETRTAFGIEFARSEAFQKGGRKGAKKVMIVITDGE 273
HLN + + +V+EA ++ +GG T T A F S + G R G K+ I+ITDG+
Sbjct: 211 HLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGK 270
Query: 274 SHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVT 333
S D D+ + V +A+ V +NE++ IAS+PD H +NV
Sbjct: 271 SQD--DIIPPSRNLRESGVELFAIGV----------KNADVNELQEIASEPDSTHVYNVA 318
Query: 334 DEAALKDIVDAL 345
+ + +V++L
Sbjct: 319 EFDLMHTVVESL 330
Score = 89.0 bits (219), Expect = 2e-17
Identities = 68/206 (33%), Positives = 107/206 (51%), Gaps = 23/206 (11%)
Query: 148 FSKTVAPALQRCQTYM-DIVIVLDGSNSIYP--WVEVQHFL---INILKKFYIGPGQIQV 201
F T+ PA + C+ D+V ++DGS SI + ++ FL + L K IG QV
Sbjct: 1015 FPPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNK--IGTDGTQV 1072
Query: 202 GVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKGGR 259
+VQ+ +D EF LN Y++ + +++A HI +GG T+T I++ R F + G R
Sbjct: 1073 AMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGG-NTKTGKAIKYVRDTLFTAESGTR 1131
Query: 260 KGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKY 319
+G KV++VITDG S D D+ K+ ++ + D + +A+ V + +E+
Sbjct: 1132 RGIPKVIVVITDGRSQD--DVNKISREMQLDGYSIFAIGV----------ADADYSELVS 1179
Query: 320 IASDPDDKHFFNVTDEAALKDIVDAL 345
I S P +H F V D A K I D L
Sbjct: 1180 IGSKPSARHVFFVDDFDAFKKIEDEL 1205
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 91.7 bits (226), Expect = 4e-18
Identities = 65/188 (34%), Positives = 97/188 (51%), Gaps = 15/188 (7%)
Query: 164 DIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRS 221
D+V +LDGS S+ P + V+ +L+NI K F IGP IQVGVVQY + V E L Y S
Sbjct: 37 DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96
Query: 222 VKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHDSPDLE 281
+ + A I GG T+T I+FA F K R K+ +V+TDG+S D D++
Sbjct: 97 GEHLTAAVESILYLGG-NTKTGKAIQFALDYLFAKSSR-FLTKIAVVLTDGKSQD--DVK 152
Query: 282 KVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDI 341
Q + +T +A+ G+ ET E++ IA+ P + F V D A+ I
Sbjct: 153 DAAQAARDSKITLFAI---------GVGSETEDAELRAIANKPSSTYVFYVEDYIAISKI 203
Query: 342 VDALGDRI 349
+ + ++
Sbjct: 204 REVMKQKL 211
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,223,268
Number of Sequences: 37866
Number of extensions: 1967861
Number of successful extensions: 4376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3848
Number of HSP's gapped (non-prelim): 185
length of query: 1188
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1075
effective length of database: 13,968,660
effective search space: 15016309500
effective search space used: 15016309500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.