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Search of human proteins with 52345626
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52345626 clusterin associated protein 1 isoform 1 [Homo
sapiens]
(413 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens] 811 0.0
gi|13435145 clusterin associated protein 1 isoform 2 [Homo sapiens] 488 e-138
gi|115529449 upstream binding transcription factor, RNA polymera... 61 2e-09
gi|115529451 upstream binding transcription factor, RNA polymera... 61 2e-09
gi|7657671 upstream binding transcription factor, RNA polymerase... 61 2e-09
gi|55956788 nucleolin [Homo sapiens] 53 4e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 53 6e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 53 6e-07
gi|42794779 myosin 18A isoform b [Homo sapiens] 52 8e-07
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 50 3e-06
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 50 3e-06
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 50 3e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 49 6e-06
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 49 6e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 49 6e-06
gi|4503917 growth arrest-specific 8 [Homo sapiens] 49 6e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 49 1e-05
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 48 1e-05
gi|28416946 myosin 18A isoform a [Homo sapiens] 48 1e-05
gi|217035164 coiled-coil domain containing 27 [Homo sapiens] 48 1e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 48 2e-05
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 47 2e-05
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 47 2e-05
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 47 2e-05
gi|216548091 leucine zipper protein 1 [Homo sapiens] 47 3e-05
gi|216548085 leucine zipper protein 1 [Homo sapiens] 47 3e-05
gi|55770834 centromere protein F [Homo sapiens] 47 3e-05
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 47 3e-05
gi|18093112 ABT1-associated protein [Homo sapiens] 47 4e-05
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 46 5e-05
>gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens]
Length = 413
Score = 811 bits (2095), Expect = 0.0
Identities = 413/413 (100%), Positives = 413/413 (100%)
Query: 1 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ 60
MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ
Sbjct: 1 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ 60
Query: 61 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE 120
DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE
Sbjct: 61 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE 120
Query: 121 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE 180
EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE
Sbjct: 121 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE 180
Query: 181 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC 240
TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC
Sbjct: 181 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC 240
Query: 241 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE 300
FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE
Sbjct: 241 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE 300
Query: 301 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD 360
EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD
Sbjct: 301 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD 360
Query: 361 SDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF 413
SDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF
Sbjct: 361 SDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF 413
>gi|13435145 clusterin associated protein 1 isoform 2 [Homo sapiens]
Length = 247
Score = 488 bits (1257), Expect = e-138
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 167 MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 226
MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER
Sbjct: 1 MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 60
Query: 227 NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE 286
NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE
Sbjct: 61 NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE 120
Query: 287 AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG 346
AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG
Sbjct: 121 AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG 180
Query: 347 RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL 406
RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL
Sbjct: 181 RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL 240
Query: 407 DESDNDF 413
DESDNDF
Sbjct: 241 DESDNDF 247
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 61.2 bits (147), Expect = 2e-09
Identities = 72/304 (23%), Positives = 130/304 (42%), Gaps = 46/304 (15%)
Query: 118 IVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY------DLLGMEVELREMRTEA 171
++ + + +FK D ++ LKA + + K ++ D E EL EMR
Sbjct: 459 VIGDYLARFKND---RVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMR--- 512
Query: 172 IARPLEINETEKV--MRIAIKEILTQVQK-TKDLLNNVASDEANLEAKIEKRKLELERNR 228
A P N ++K+ K + QK +++LL+N E N +++R +E+
Sbjct: 513 -APPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSN---GELN-HLPLKERMVEIGSRW 567
Query: 229 KRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAK 288
+R+ Q + Y+K EE QKQY +L+ +++ +E +
Sbjct: 568 QRISQSQK------EHYKKLAEEQQKQYKVHLD-----LWVKSLSPQDRAAYKEYISNKR 616
Query: 289 NTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRP 348
++ ++ + + L+S S + D + EDDE + E EE G
Sbjct: 617 KSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD-----------ENGDS 665
Query: 349 GKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDE 408
+ + + D++ED +E+E D ED+DD++DD EDE + + S D
Sbjct: 666 SEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS----SSSSGDS 721
Query: 409 SDND 412
SD+D
Sbjct: 722 SDSD 725
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 61.2 bits (147), Expect = 2e-09
Identities = 72/304 (23%), Positives = 130/304 (42%), Gaps = 46/304 (15%)
Query: 118 IVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY------DLLGMEVELREMRTEA 171
++ + + +FK D ++ LKA + + K ++ D E EL EMR
Sbjct: 459 VIGDYLARFKND---RVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMR--- 512
Query: 172 IARPLEINETEKV--MRIAIKEILTQVQK-TKDLLNNVASDEANLEAKIEKRKLELERNR 228
A P N ++K+ K + QK +++LL+N E N +++R +E+
Sbjct: 513 -APPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSN---GELN-HLPLKERMVEIGSRW 567
Query: 229 KRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAK 288
+R+ Q + Y+K EE QKQY +L+ +++ +E +
Sbjct: 568 QRISQSQK------EHYKKLAEEQQKQYKVHLD-----LWVKSLSPQDRAAYKEYISNKR 616
Query: 289 NTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRP 348
++ ++ + + L+S S + D + EDDE + E EE G
Sbjct: 617 KSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD-----------ENGDS 665
Query: 349 GKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDE 408
+ + + D++ED +E+E D ED+DD++DD EDE + + S D
Sbjct: 666 SEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS----SSSSGDS 721
Query: 409 SDND 412
SD+D
Sbjct: 722 SDSD 725
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 61.2 bits (147), Expect = 2e-09
Identities = 72/304 (23%), Positives = 130/304 (42%), Gaps = 46/304 (15%)
Query: 118 IVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY------DLLGMEVELREMRTEA 171
++ + + +FK D ++ LKA + + K ++ D E EL EMR
Sbjct: 496 VIGDYLARFKND---RVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMR--- 549
Query: 172 IARPLEINETEKV--MRIAIKEILTQVQK-TKDLLNNVASDEANLEAKIEKRKLELERNR 228
A P N ++K+ K + QK +++LL+N E N +++R +E+
Sbjct: 550 -APPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSN---GELN-HLPLKERMVEIGSRW 604
Query: 229 KRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAK 288
+R+ Q + Y+K EE QKQY +L+ +++ +E +
Sbjct: 605 QRISQSQK------EHYKKLAEEQQKQYKVHLD-----LWVKSLSPQDRAAYKEYISNKR 653
Query: 289 NTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRP 348
++ ++ + + L+S S + D + EDDE + E EE G
Sbjct: 654 KSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD-----------ENGDS 702
Query: 349 GKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDE 408
+ + + D++ED +E+E D ED+DD++DD EDE + + S D
Sbjct: 703 SEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS----SSSSGDS 758
Query: 409 SDND 412
SD+D
Sbjct: 759 SDSD 762
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 53.1 bits (126), Expect = 4e-07
Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 21/118 (17%)
Query: 303 KRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSD 362
K K S+++ D D +ED+E D + +E AM+ +
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMK-------------AAAAAPAS 184
Query: 363 DNEDSEESEIDMEDDDDEDDDLEDESISLSPTK--------PNRRVRKSEPLDESDND 412
++ED E+ E D +DDDDE+DD E+E++ +P K P + +E DE ++D
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDD 242
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 5/94 (5%)
Query: 312 DDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGK-RIVGTMQGGDSDDNEDSEES 370
DD D D E+D+S+ E E K + A +++ P K + V + + DD ++ ++
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVV----PVKAKNVAEDEDEEEDDEDEDDDD 249
Query: 371 EIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSE 404
+ D EDDDDEDD+ E+E P K RK E
Sbjct: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 15/113 (13%)
Query: 310 SNDDSDIDIQEDDESDSELEERRLPKPQTAMEML-MQGRPGKRIVGTMQGG--------- 359
+++D D + EDDE D + EE + AME +G+ ++V
Sbjct: 183 ASEDEDDEDDEDDEDDDDDEED--DSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240
Query: 360 ---DSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDES 409
D DD++D ++ + D EDD++E+++ E+E + +P K + + K + E+
Sbjct: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEA 293
Score = 34.7 bits (78), Expect = 0.16
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 348 PGKR-----IVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRK 402
PGK+ G G ++ + EE + D E+D+++D+D +++ + P
Sbjct: 122 PGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA 181
Query: 403 SEPLDESDND 412
DE D D
Sbjct: 182 PASEDEDDED 191
Score = 30.0 bits (66), Expect = 4.0
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 15/78 (19%)
Query: 348 PGKRIVGT------------MQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTK 395
PGK +V T + G + EDS+E E D + ++DE+DD EDE +
Sbjct: 114 PGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDD-DSEEDEEDD-EDEDEDEDEIE 171
Query: 396 P-NRRVRKSEPLDESDND 412
P + + P E ++D
Sbjct: 172 PAAMKAAAAAPASEDEDD 189
Score = 29.3 bits (64), Expect = 6.8
Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 6/57 (10%)
Query: 295 QNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKR 351
+N ++E++ +DD D D ++DD+ D E EE + E ++ PGKR
Sbjct: 230 KNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEE------EEEEEEPVKEAPGKR 280
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 52.8 bits (125), Expect = 6e-07
Identities = 50/229 (21%), Positives = 100/229 (43%), Gaps = 28/229 (12%)
Query: 186 RIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEY 245
RIA K +L +++ N++SDE E E +KR P
Sbjct: 1232 RIAKKMLLEEIKA------NLSSDEDGSSDD------EPEEGKKRTGKQNEENP----GD 1275
Query: 246 EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRL 305
E+ + ++ + D+ E+ + Y + L + E K T ++K +R
Sbjct: 1276 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335
Query: 306 LKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG-------RPGKRIVGTMQG 358
+ S ++DSD E SE E+ + P+ ++A + ++ + +R + +
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1395
Query: 359 GDSDDNEDSEESEIDMEDDDDEDDDLEDE-----SISLSPTKPNRRVRK 402
S++ +SEE E + E++++E+++ E+E S SP K +++RK
Sbjct: 1396 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK 1444
Score = 28.9 bits (63), Expect = 8.9
Identities = 34/144 (23%), Positives = 62/144 (43%), Gaps = 28/144 (19%)
Query: 270 EQQLEDHHRMEQERFEEAKNTLCLIQ--NKLKEEEKRLLKSGSNDDSDIDIQEDDES--- 324
E+ ED+ + +Q + K + + N L+ KR ++ S DI++DD++
Sbjct: 1121 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK-QADITSSSSSDIEDDDQNSIG 1179
Query: 325 DSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDL 384
+ +E+++ KP T +L G Q S D S+ + ++DDDD++D
Sbjct: 1180 EGSSDEQKI-KPVTENLVLSSH------TGFCQS--SGDEALSKSVPVTVDDDDDDND-- 1228
Query: 385 EDESISLSPTKPNRRVRKSEPLDE 408
P R+ K L+E
Sbjct: 1229 -----------PENRIAKKMLLEE 1241
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 52.8 bits (125), Expect = 6e-07
Identities = 50/229 (21%), Positives = 100/229 (43%), Gaps = 28/229 (12%)
Query: 186 RIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEY 245
RIA K +L +++ N++SDE E E +KR P
Sbjct: 1270 RIAKKMLLEEIKA------NLSSDEDGSSDD------EPEEGKKRTGKQNEENP----GD 1313
Query: 246 EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRL 305
E+ + ++ + D+ E+ + Y + L + E K T ++K +R
Sbjct: 1314 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1373
Query: 306 LKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG-------RPGKRIVGTMQG 358
+ S ++DSD E SE E+ + P+ ++A + ++ + +R + +
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1433
Query: 359 GDSDDNEDSEESEIDMEDDDDEDDDLEDE-----SISLSPTKPNRRVRK 402
S++ +SEE E + E++++E+++ E+E S SP K +++RK
Sbjct: 1434 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK 1482
Score = 28.9 bits (63), Expect = 8.9
Identities = 34/144 (23%), Positives = 62/144 (43%), Gaps = 28/144 (19%)
Query: 270 EQQLEDHHRMEQERFEEAKNTLCLIQ--NKLKEEEKRLLKSGSNDDSDIDIQEDDES--- 324
E+ ED+ + +Q + K + + N L+ KR ++ S DI++DD++
Sbjct: 1159 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK-QADITSSSSSDIEDDDQNSIG 1217
Query: 325 DSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDL 384
+ +E+++ KP T +L G Q S D S+ + ++DDDD++D
Sbjct: 1218 EGSSDEQKI-KPVTENLVLSSH------TGFCQS--SGDEALSKSVPVTVDDDDDDND-- 1266
Query: 385 EDESISLSPTKPNRRVRKSEPLDE 408
P R+ K L+E
Sbjct: 1267 -----------PENRIAKKMLLEE 1279
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 52.4 bits (124), Expect = 8e-07
Identities = 64/318 (20%), Positives = 137/318 (43%), Gaps = 18/318 (5%)
Query: 83 TKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQ 142
++K + D K LL ++ + +K EI + N+ + + A +KA +
Sbjct: 1650 SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLK-NQLEESEFTCAAAVKARKA 1708
Query: 143 LASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDL 202
+ EI + D+ + L E + E NE + + +++ ++K K
Sbjct: 1709 MEVEIEDLHLQIDDIAKAKTALEEQLSRL---QREKNEIQNRLEEDQEDMNELMKKHKAA 1765
Query: 203 LNNVASDEA---NLEAKIEKRKLELERNRKRLETLQS----VRPCFMDEYEKTEEELQ-K 254
+ + D A +L+A++E+ E + +++L+ LQS + +D+ + +E + +
Sbjct: 1766 VAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIR 1825
Query: 255 QYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDS 314
+ +T LE + + L + E+ E ++ +N+ KE+ KRL + +
Sbjct: 1826 ELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKE 1885
Query: 315 DIDIQEDDESDSELEERRLPKPQTAMEMLMQG-----RPGKRIVGTMQGGDSDDNE-DSE 368
++ E+++ ++ L ++E Q + + +G +Q D+ E D
Sbjct: 1886 EMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDEN 1945
Query: 369 ESEIDMEDDDDEDDDLED 386
E I+ E D D D +LED
Sbjct: 1946 EDLINSEGDSDVDSELED 1963
Score = 41.6 bits (96), Expect = 0.001
Identities = 53/257 (20%), Positives = 110/257 (42%), Gaps = 43/257 (16%)
Query: 181 TEKVMRIA--IKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE----------LERNR 228
T+KV+ + +++I +Q K + L V +LEAK++ ++ E LE+ +
Sbjct: 1513 TQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAK 1572
Query: 229 KRLE-TLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNL-TYLEQQLEDHHRMEQERFEE 286
RLE ++ +R E E +EE+++ + +K + + LE++ ED ++ +E+ E
Sbjct: 1573 LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREK-RE 1631
Query: 287 AKNTLCLIQNKLK----EEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM 342
+ L + +++ E EKRL K D + + L Q ++
Sbjct: 1632 LEGKLATLSDQVNRRDFESEKRLRK-----------------DLKRTKALLADAQLMLDH 1674
Query: 343 LMQGRPGKRIVGTMQGGDSDDN-------EDSEESEIDMEDDDDEDDDLEDESISLSPTK 395
L P KR + ++ + + + E+++ED + DD+ +L
Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
Query: 396 PNRRVRKSEPLDESDND 412
+ K+E + + D
Sbjct: 1735 SRLQREKNEIQNRLEED 1751
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 50.4 bits (119), Expect = 3e-06
Identities = 67/306 (21%), Positives = 131/306 (42%), Gaps = 23/306 (7%)
Query: 108 MKTKGMEGSEIVEEDVNKFKFD---LGSKIADLKAARQLASEITSKGASLYDLLGMEVEL 164
+K E E +E NK D G K ++ L +I LY + +
Sbjct: 400 LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRK 459
Query: 165 REMRTEAIARPLEINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE 223
+ + I EIN EK +R+ + I +V + LN++ ++ A L +K+EK K
Sbjct: 460 EKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHN 519
Query: 224 LERNRKRLETLQSVRPCFMDEY----EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRM 279
ER +E+L S ++EY E+ + EL + + + + QL D + +
Sbjct: 520 KERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNEL 579
Query: 280 EQERFEEAKNTLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDDESDSEL---------- 328
E+ +A+ ++ KL+E L K+ + + +D+++ E+
Sbjct: 580 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 639
Query: 329 EERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLE 385
E + + K ++ E + Q R + ++ Q D+ D++E I++ D + ++D LE
Sbjct: 640 ESQSIGKQNSSEERIRQ-RELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLE 698
Query: 386 DESISL 391
+ + L
Sbjct: 699 ERNKEL 704
Score = 37.7 bits (86), Expect = 0.019
Identities = 54/227 (23%), Positives = 94/227 (41%), Gaps = 22/227 (9%)
Query: 41 WLVKRYEPQTDIPPDVDTEQDR-VFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLK 99
W K+ Q +I P+ E+ R VF + ++ + A + K N + +A GY K+ L+
Sbjct: 764 WTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIR-KKNRELEEEATGY--KKCLE 820
Query: 100 ITSVLYNAMKTKGMEGSEIVEEDVNKFKF---DLGSKIADLKAARQLASEITSKGASLYD 156
+T + NA + + D K L K DL A ++ S A +
Sbjct: 821 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 880
Query: 157 LLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAK 216
+L E+ L + + ++ K+ +K +L ++ D L K
Sbjct: 881 VLHQEL-------------LSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVEL-GK 926
Query: 217 IEKRKLEL-ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEK 262
+++ K EL ER + +E L+ + EYEK E+L K L+K
Sbjct: 927 VQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK 973
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 50.4 bits (119), Expect = 3e-06
Identities = 67/306 (21%), Positives = 131/306 (42%), Gaps = 23/306 (7%)
Query: 108 MKTKGMEGSEIVEEDVNKFKFD---LGSKIADLKAARQLASEITSKGASLYDLLGMEVEL 164
+K E E +E NK D G K ++ L +I LY + +
Sbjct: 429 LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRK 488
Query: 165 REMRTEAIARPLEINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE 223
+ + I EIN EK +R+ + I +V + LN++ ++ A L +K+EK K
Sbjct: 489 EKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHN 548
Query: 224 LERNRKRLETLQSVRPCFMDEY----EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRM 279
ER +E+L S ++EY E+ + EL + + + + QL D + +
Sbjct: 549 KERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNEL 608
Query: 280 EQERFEEAKNTLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDDESDSEL---------- 328
E+ +A+ ++ KL+E L K+ + + +D+++ E+
Sbjct: 609 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 668
Query: 329 EERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLE 385
E + + K ++ E + Q R + ++ Q D+ D++E I++ D + ++D LE
Sbjct: 669 ESQSIGKQNSSEERIRQ-RELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLE 727
Query: 386 DESISL 391
+ + L
Sbjct: 728 ERNKEL 733
Score = 37.7 bits (86), Expect = 0.019
Identities = 54/227 (23%), Positives = 94/227 (41%), Gaps = 22/227 (9%)
Query: 41 WLVKRYEPQTDIPPDVDTEQDR-VFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLK 99
W K+ Q +I P+ E+ R VF + ++ + A + K N + +A GY K+ L+
Sbjct: 793 WTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIR-KKNRELEEEATGY--KKCLE 849
Query: 100 ITSVLYNAMKTKGMEGSEIVEEDVNKFKF---DLGSKIADLKAARQLASEITSKGASLYD 156
+T + NA + + D K L K DL A ++ S A +
Sbjct: 850 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909
Query: 157 LLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAK 216
+L E+ L + + ++ K+ +K +L ++ D L K
Sbjct: 910 VLHQEL-------------LSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVEL-GK 955
Query: 217 IEKRKLEL-ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEK 262
+++ K EL ER + +E L+ + EYEK E+L K L+K
Sbjct: 956 VQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK 1002
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 50.4 bits (119), Expect = 3e-06
Identities = 67/306 (21%), Positives = 131/306 (42%), Gaps = 23/306 (7%)
Query: 108 MKTKGMEGSEIVEEDVNKFKFD---LGSKIADLKAARQLASEITSKGASLYDLLGMEVEL 164
+K E E +E NK D G K ++ L +I LY + +
Sbjct: 429 LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRK 488
Query: 165 REMRTEAIARPLEINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE 223
+ + I EIN EK +R+ + I +V + LN++ ++ A L +K+EK K
Sbjct: 489 EKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHN 548
Query: 224 LERNRKRLETLQSVRPCFMDEY----EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRM 279
ER +E+L S ++EY E+ + EL + + + + QL D + +
Sbjct: 549 KERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNEL 608
Query: 280 EQERFEEAKNTLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDDESDSEL---------- 328
E+ +A+ ++ KL+E L K+ + + +D+++ E+
Sbjct: 609 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 668
Query: 329 EERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLE 385
E + + K ++ E + Q R + ++ Q D+ D++E I++ D + ++D LE
Sbjct: 669 ESQSIGKQNSSEERIRQ-RELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLE 727
Query: 386 DESISL 391
+ + L
Sbjct: 728 ERNKEL 733
Score = 37.7 bits (86), Expect = 0.019
Identities = 54/227 (23%), Positives = 94/227 (41%), Gaps = 22/227 (9%)
Query: 41 WLVKRYEPQTDIPPDVDTEQDR-VFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLK 99
W K+ Q +I P+ E+ R VF + ++ + A + K N + +A GY K+ L+
Sbjct: 793 WTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIR-KKNRELEEEATGY--KKCLE 849
Query: 100 ITSVLYNAMKTKGMEGSEIVEEDVNKFKF---DLGSKIADLKAARQLASEITSKGASLYD 156
+T + NA + + D K L K DL A ++ S A +
Sbjct: 850 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909
Query: 157 LLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAK 216
+L E+ L + + ++ K+ +K +L ++ D L K
Sbjct: 910 VLHQEL-------------LSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVEL-GK 955
Query: 217 IEKRKLEL-ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEK 262
+++ K EL ER + +E L+ + EYEK E+L K L+K
Sbjct: 956 VQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK 1002
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 49.3 bits (116), Expect = 6e-06
Identities = 67/335 (20%), Positives = 141/335 (42%), Gaps = 62/335 (18%)
Query: 125 KFKFDLGSKIADL----KAARQLASEITSKGASLYD-------------LLGMEVELREM 167
K KF L +KI ++ + ++ +E+T+K L D L +VE +
Sbjct: 911 KAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 970
Query: 168 RTEAIARPL------------EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 215
TE + L ++ +K ++ A ++ L +Q +D +N++ ++ LE
Sbjct: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQ 1030
Query: 216 KIE----------KRKLELERNRKRLE-TLQSVRPCFMD---EYEKTEEELQKQYDTYLE 261
++E K +++LERN+++LE L+ + +D + ++ +E L+K+ Y +
Sbjct: 1031 QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQ 1090
Query: 262 -----------------KFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKR 304
K + L ++LE+ E+ + + +L+E +R
Sbjct: 1091 LQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSER 1150
Query: 305 LLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDN 364
L ++G + I++ + E++ R L + E ++ K + G+ DN
Sbjct: 1151 LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDN 1210
Query: 365 EDSEESEIDMEDDDD--EDDDLEDESISLSPTKPN 397
+ +++ E + E DDL S+S +K N
Sbjct: 1211 LQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKAN 1245
Score = 33.9 bits (76), Expect = 0.28
Identities = 36/170 (21%), Positives = 75/170 (44%), Gaps = 22/170 (12%)
Query: 169 TEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNR 228
T+AI R E+ E +K + +++ QV+ ++ + L+ ++E +++ER
Sbjct: 1378 TDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
Query: 229 KRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERF---- 284
L D+ ++ +++ ++ T E+ Q LE L++ + E F
Sbjct: 1438 SLAAAL--------DKKQRNFDKVLAEWKTKCEESQ--AELEASLKESRSLSTELFKLKN 1487
Query: 285 --EEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERR 332
EEA + L ++ + K E+ + D I E+ ++ ELE+ R
Sbjct: 1488 AYEEALDQLETVKRENKNLEQEIA------DLTEQIAENGKTIHELEKSR 1531
Score = 31.2 bits (69), Expect = 1.8
Identities = 39/195 (20%), Positives = 84/195 (43%), Gaps = 24/195 (12%)
Query: 104 LYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGME-- 161
L + T + + +E D+ + + ++ D + A + A + + A + + L E
Sbjct: 1716 LLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQD 1775
Query: 162 ----VELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNV-----ASDEAN 212
+E + E + L+ + ++ ++A+K Q+QK + + + + N
Sbjct: 1776 TSAHLERMKKNLEQTVKDLQ-HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 1834
Query: 213 LEA-----KIEKRKLEL----ERNRK---RLETLQSVRPCFMDEYEKTEEELQKQYDTYL 260
E+ K E+R EL E +RK RL+ L + Y++ EE +Q + +L
Sbjct: 1835 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL 1894
Query: 261 EKFQNLTYLEQQLED 275
KF+ + ++ E+
Sbjct: 1895 TKFRKAQHELEEAEE 1909
Score = 30.8 bits (68), Expect = 2.3
Identities = 47/225 (20%), Positives = 89/225 (39%), Gaps = 21/225 (9%)
Query: 135 ADLKAARQLASEITSKGASLYDLL-----------GMEVELREMRTEAIARPLEINETEK 183
A LK +R L++E+ + + L +E E+ ++ + I+E EK
Sbjct: 1470 ASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEK 1529
Query: 184 VMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLEL-----ERNRKRLETLQSVR 238
+ K+I + + L + + EAKI + +LEL E +RK E + +
Sbjct: 1530 ----SRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585
Query: 239 PCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKL 298
Y++T E +Q D + L++++E + + A L
Sbjct: 1586 Q-LKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHL 1644
Query: 299 KEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEML 343
+ + +L + + D + QED + + ERR Q +E L
Sbjct: 1645 RSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEEL 1689
Score = 29.6 bits (65), Expect = 5.2
Identities = 34/205 (16%), Positives = 90/205 (43%), Gaps = 12/205 (5%)
Query: 129 DLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIA 188
+LG +I +L+ +Q + S+ +E++ E++++ EK+ R
Sbjct: 1203 ELGEQIDNLQRVKQKLEKEKSE-------FKLEIDDLSSSMESVSKSKA--NLEKICR-T 1252
Query: 189 IKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKT 248
+++ L++ + + + S+ +++++ EL R + E++ S + +
Sbjct: 1253 LEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQ 1312
Query: 249 EEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 308
EEL++Q + + L + Q + +E++EE + +Q L + + +
Sbjct: 1313 TEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1372
Query: 309 GSNDDSDI--DIQEDDESDSELEER 331
+ ++D +E +E+ +L +R
Sbjct: 1373 RTKYETDAIQRTEELEEAKKKLAQR 1397
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 49.3 bits (116), Expect = 6e-06
Identities = 66/315 (20%), Positives = 135/315 (42%), Gaps = 31/315 (9%)
Query: 94 VKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLK-AARQLASEITSKGA 152
+K+L + L+ +TK E + ++ E ++K K D+ S + +K A +L +E+ S
Sbjct: 350 IKQLSQEKGRLHQLYETKEGETTRLIRE-IDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 408
Query: 153 SLYDLLGMEVELREMRTEAI---------------ARPLEINETEKVMRIAIKEILTQVQ 197
+ L +L + + EA + ++ NE + +R+ E+ Q+Q
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 198 KTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYD 257
+ D L A ++ ++E K + L TL++ C DE +TE+EL K +
Sbjct: 469 EKSDQLE---MHHAKIK-ELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKE 524
Query: 258 TYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDID 317
+ + L +++ ++ QE+ + K + LKEE + L ++ DI+
Sbjct: 525 IINRQKAEIQNLLDKVKTADQL-QEQLQRGKQEI----ENLKEEVESLNSLINDLQKDIE 579
Query: 318 IQEDDESDSELEERRLPKPQTAMEM---LMQGRPGKRIVGTMQGGDSDDNEDSEESEIDM 374
ES+ L RL ++ +Q + K V + E +++ I++
Sbjct: 580 GSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDK--VSCSESQLQSQCEQMKQTNINL 637
Query: 375 EDDDDEDDDLEDESI 389
E ++++L E +
Sbjct: 638 ESRLLKEEELRKEEV 652
Score = 39.3 bits (90), Expect = 0.007
Identities = 67/299 (22%), Positives = 129/299 (43%), Gaps = 30/299 (10%)
Query: 59 EQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEI 118
E V F K + + HI KKL + + + + I S N ++ + + +E
Sbjct: 188 EHALVLFEKCVQDKYLQQEHI---IKKLIKENKKHQELFVDICSEKDN-LREELKKRTET 243
Query: 119 VEEDVNKFKFDLGSKIADL----KAARQ--LASEITSKGASLYDLLGMEVELREMRTEAI 172
++ +N K L S+I +L KA+R +A ++T+K A + + E+ + +A
Sbjct: 244 EKQHMNTIK-QLESRIEELNKEVKASRDQLIAQDVTAKNA----VQQLHKEMAQRMEQAN 298
Query: 173 ARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLE 232
+ E + ++ M ++ V+ K+ L+ + ++ LE K+ ELE+N +++
Sbjct: 299 KKCEEARQEKEAM------VMKYVRGEKESLD-LRKEKETLEKKLRDANKELEKNTNKIK 351
Query: 233 TLQSVRPCFMDEYEKTEEE---LQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKN 289
L + YE E E L ++ D E + + ++ + E + +E K+
Sbjct: 352 QLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKD 411
Query: 290 TLCLIQNKL---KEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQ 345
L KL KEE ++ K + D QE +E S + +L + +E MQ
Sbjct: 412 KLKETTTKLTQAKEEADQIRK--NCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 49.3 bits (116), Expect = 6e-06
Identities = 56/287 (19%), Positives = 127/287 (44%), Gaps = 33/287 (11%)
Query: 109 KTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMR 168
K K E S+ +E + N + +K +LK L E+T +LL +++
Sbjct: 1856 KQKNKEFSQTLENEKNTLLSQISTKDGELK---MLQEEVTK-----MNLLNQQIQ----- 1902
Query: 169 TEAIARPLEINETEKVMRIAIKE-ILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERN 227
E ++R ++ ET + + ++E ++ Q+ + + N D + + K E + E++
Sbjct: 1903 -EELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNL 1961
Query: 228 RKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEA 287
+K + L+ + + E K E E++K+ YLEK Q E + H + QE +E
Sbjct: 1962 KKCVSELEEEKQQLVKEKTKVESEIRKE---YLEKIQG-AQKEPGNKSHAKELQELLKEK 2017
Query: 288 KNTLCLIQ----------NKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQ 337
+ + +Q + L+ K L + D++I +++ + + ++
Sbjct: 2018 QQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAEL 2077
Query: 338 TAMEMLM---QGRPGKRIVGTMQ-GGDSDDNEDSEESEIDMEDDDDE 380
+ ++L+ Q + + ++ + N++S +S++ +D+D E
Sbjct: 2078 ASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLE 2124
Score = 45.8 bits (107), Expect = 7e-05
Identities = 41/213 (19%), Positives = 98/213 (46%), Gaps = 20/213 (9%)
Query: 191 EILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEE 250
+++T++ ++ +++S +L+ +E + E+ K +E+L+S + E+++ +
Sbjct: 1550 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHK 1609
Query: 251 ELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGS 310
ELQK+Y+ L+ ++N++ ++++ ++ +E L + KE EK+L ++
Sbjct: 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAE- 1668
Query: 311 NDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQ-----------GRPGKRIVGTMQGG 359
QE +E ++ + K Q +E+ + G K + T+
Sbjct: 1669 --------QEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSS 1720
Query: 360 DSDDNEDSEESEIDMEDDDDEDDDLEDESISLS 392
++ E+ E +++ E + L E SLS
Sbjct: 1721 NASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1753
Score = 37.4 bits (85), Expect = 0.025
Identities = 55/295 (18%), Positives = 118/295 (40%), Gaps = 42/295 (14%)
Query: 156 DLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 215
+LL E R + + ++ K ++ + ++ ++K K+ N+ EA
Sbjct: 2288 ELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2347
Query: 216 KIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEE------------------ELQKQYD 257
I+ K E+ L+ + + +E E+ EL++Q+D
Sbjct: 2348 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD 2407
Query: 258 TYLEKFQNLTYLEQQ----LEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRL---LKSGS 310
+++ +NL E++ LE+ ++ ++ + TL I+ + +++ +L +KS S
Sbjct: 2408 KEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMS 2467
Query: 311 NDDSDIDIQEDDESDSELEERR----LPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNED 366
+ +D D D +LEER L K Q E + K + ++ D N +
Sbjct: 2468 SLQNDRDRIVGDY--QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSE 2525
Query: 367 SEESEIDM----ED-------DDDEDDDLEDESISLSPTKPNRRVRKSEPLDESD 410
+ + + ++ ED D + L + + + N+ + E L ES+
Sbjct: 2526 NAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESE 2580
Score = 35.8 bits (81), Expect = 0.073
Identities = 64/320 (20%), Positives = 134/320 (41%), Gaps = 28/320 (8%)
Query: 84 KKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQ- 142
++L QA+ +KE + L +A++ + + +EE + + + L K +++ ++
Sbjct: 2125 RRLEQAEEKHLKEKKNMQEKL-DALRREKVH----LEETIGEIQVTLNKKDKEVQQLQEN 2179
Query: 143 LASEITSKGASLYDLLGMEVELREMRTEAIARPLEINET--EKVMRIAIKEILTQVQKTK 200
L S +T A + ++ + + EA + ++ K I +KE V K +
Sbjct: 2180 LDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQ 2239
Query: 201 ---------DLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEE 251
+L N++ E + + K + E++ +K +TLQ + + E+T
Sbjct: 2240 LRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2299
Query: 252 LQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSG-S 310
+ + L L+ QL D E+ +E K L + ++++E + S S
Sbjct: 2300 YHSSQNELAKLESELKSLKDQLTDLSN-SLEKCKEQKGNL---EGIIRQQEADIQNSKFS 2355
Query: 311 NDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEES 370
+ + D+Q E S L E K Q + +L GK + + D E
Sbjct: 2356 YEQLETDLQASRELTSRLHEEINMKEQKIISLL----SGKEEAIQVAIAELRQQHDKEIK 2411
Query: 371 EID--MEDDDDEDDDLEDES 388
E++ + +++E+ LE+E+
Sbjct: 2412 ELENLLSQEEEENIVLEEEN 2431
Score = 35.0 bits (79), Expect = 0.12
Identities = 46/230 (20%), Positives = 98/230 (42%), Gaps = 36/230 (15%)
Query: 113 MEGSEIVEEDVNKFKFDLGSKIADLK-AARQLASEITSKGASLYD-LLGMEVELREMRTE 170
ME + +EDV + + +LK RQ ++ K +L + + ++++++
Sbjct: 40 MEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLH 99
Query: 171 AIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKR 230
A A+ +N+ + M+ +L ++++ L+ E +IEK K +L+ +
Sbjct: 100 AKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEEL 159
Query: 231 LETLQ-----------SVRPCFMDEYEKTEEELQ--KQYDTYLEKFQNLTYLEQQLEDHH 277
+ TLQ + M+E+ +++LQ +++ + L+ + T EQ +
Sbjct: 160 ISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVV 219
Query: 278 RMEQERFE---------------------EAKNTLCLIQNKLKEEEKRLL 306
R + RFE E + L ++Q KL+E E+ L+
Sbjct: 220 REKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLV 269
Score = 35.0 bits (79), Expect = 0.12
Identities = 45/214 (21%), Positives = 93/214 (43%), Gaps = 21/214 (9%)
Query: 120 EEDVNKFKFDLGSKIADLKAARQLASEITSK---GASLYDLLGMEVELREMRTEAIARPL 176
E ++ + DL K+A + + L ++ + DLL E+ +AI + L
Sbjct: 1070 EVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEIS----ENQAIIQKL 1125
Query: 177 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQS 236
+ T+ ++ + V + + + LE KI + E E+ +K+L+ +
Sbjct: 1126 ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALT 1185
Query: 237 VRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQN 296
R + + ++ E L+++ L+QQ +D++R+ QE+F+E I +
Sbjct: 1186 SRKAILKKAQEKERHLREE-------------LKQQKDDYNRL-QEQFDEQSKENENIGD 1231
Query: 297 KLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEE 330
+L++ + ++ +S D QE S LEE
Sbjct: 1232 QLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEE 1265
Score = 34.7 bits (78), Expect = 0.16
Identities = 43/166 (25%), Positives = 75/166 (45%), Gaps = 6/166 (3%)
Query: 170 EAIARPLEINETEKVMRIAI-KEILTQ-VQKTKDLLNNVASDEANLEAKIEKRKLELERN 227
E + LE +TE + I KE L Q V+ K +AS + L+ + L N
Sbjct: 2039 ERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADN 2098
Query: 228 RKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEA 287
K + LQS + + ++ +E+L+++ + EK Q+ D R E+ EE
Sbjct: 2099 LKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEE- 2157
Query: 288 KNTLCLIQNKLKEEEKRLLKSGSNDDSDI-DIQEDDESDSELEERR 332
T+ IQ L +++K + + N DS + + +S S L++ R
Sbjct: 2158 --TIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDR 2201
Score = 33.5 bits (75), Expect = 0.36
Identities = 57/245 (23%), Positives = 100/245 (40%), Gaps = 31/245 (12%)
Query: 83 TKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADL--KAA 140
T LY A +E + S L+++ + + E +EE++ + + K+ ++ K
Sbjct: 2626 TLGLYHAQLKVKEEEVHRLSALFSSSQKRIAE----LEEELVCVQKEAAKKVGEIEDKLK 2681
Query: 141 RQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKE---ILTQVQ 197
++L G ++ E E E R +AR L E E+ + + KE + Q+Q
Sbjct: 2682 KELKHLHHDAG-----IMRNETETAEERVAELARDLV--EMEQKLLMVTKENKGLTAQIQ 2734
Query: 198 KTKDLLNNVAS--DEANLEAKIEKRKLELER------------NRKRLETLQSVRPCFMD 243
++++ + D AN E KRK + NR+R L
Sbjct: 2735 SFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNS 2794
Query: 244 EYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEK 303
E + L+K L K + L +L QLED + Q F +A +L ++ L E +
Sbjct: 2795 TEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQS-FSKAMASLQNERDHLWNELE 2853
Query: 304 RLLKS 308
+ KS
Sbjct: 2854 KFRKS 2858
Score = 32.7 bits (73), Expect = 0.62
Identities = 42/182 (23%), Positives = 74/182 (40%), Gaps = 17/182 (9%)
Query: 95 KELLKITSVLYNAMKTKGMEGSEI--VEEDVNKFKFDLGSKIADLKAARQLASEITSKGA 152
KEL K +L + + E I V E V + K +L K+ +A ++ + +
Sbjct: 1609 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAE 1668
Query: 153 SLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEAN 212
++ M+ ++R+ + LE+ E +R E+ K+ + + S A+
Sbjct: 1669 Q--EMEEMKEKMRKFAKSKQQKILELEEENDRLRA---EVHPAGDTAKECMETLLSSNAS 1723
Query: 213 LEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQ---KQYDTYLEKFQNLTYL 269
+ K ELER + ETL M E + EE+Q Q + + K NL
Sbjct: 1724 M-------KEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAT 1776
Query: 270 EQ 271
E+
Sbjct: 1777 EK 1778
Score = 32.0 bits (71), Expect = 1.1
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 31/201 (15%)
Query: 102 SVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLAS-EITSKGASL------ 154
S+L N + E ++ E + + K L +I LK+++ S E K L
Sbjct: 1558 SLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEI 1617
Query: 155 ----YDLLGMEVELREMRTEAIA----------RPLEIN--ETEKVMRIAIKEILTQVQK 198
Y+ + E E + EA+ R E N ETEK ++ A +E+ +K
Sbjct: 1618 LLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677
Query: 199 TKDLLNNVASDEANLEAKIEKRKLEL----ERNRKRLETLQSVRPCFMDEYEKTEEELQK 254
+ + LE + ++ + E+ + ++ +ETL S +E E+ + E
Sbjct: 1678 MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME--- 1734
Query: 255 QYDTYLEKFQNLTYLEQQLED 275
Y+T +KFQ+L + L +
Sbjct: 1735 -YETLSKKFQSLMSEKDSLSE 1754
Score = 31.6 bits (70), Expect = 1.4
Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 27/171 (15%)
Query: 160 MEVELREMRTEAIARPLEINETEKVMRIAIKEILT-QVQKTKDLLN----NVASDEANLE 214
++ +L+E+ E + L+++ T + +E+ Q Q K L S EA +
Sbjct: 1307 IKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVH 1366
Query: 215 AKIEKRKLELERNR-KRLETLQSVRPCFMDEYEKT------------------EEELQKQ 255
A+ ++KLE + + LE L+ ++P +DE +K E L K
Sbjct: 1367 AESLQQKLESSQLQIAGLEHLRELQPK-LDELQKLISKKEEDVSYLSGQLSEKEAALTKI 1425
Query: 256 YDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE--EEKR 304
+E+ + L QLE + ER ++ + LC ++ K +E EE R
Sbjct: 1426 QTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESR 1476
Score = 31.6 bits (70), Expect = 1.4
Identities = 40/205 (19%), Positives = 86/205 (41%), Gaps = 24/205 (11%)
Query: 201 DLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYL 260
D +NN L+ +I + E ++N++ +TL++ + + + + EL+
Sbjct: 1833 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELK----MLQ 1888
Query: 261 EKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDI-DIQ 319
E+ + L QQ+++ + E A+ ++ +L + L S N D+ D Q
Sbjct: 1889 EEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQ 1948
Query: 320 EDDE-------------SDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNED 366
+E S+ E E+++L K +T +E ++ K + +QG +
Sbjct: 1949 IKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR----KEYLEKIQGAQKEPGNK 2004
Query: 367 SEESEID--MEDDDDEDDDLEDESI 389
S E+ +++ E L+ + I
Sbjct: 2005 SHAKELQELLKEKQQEVKQLQKDCI 2029
Score = 30.0 bits (66), Expect = 4.0
Identities = 33/178 (18%), Positives = 80/178 (44%), Gaps = 23/178 (12%)
Query: 163 ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL 222
++ + EA ++ ++I +V++ + ++ Q + L+ + L+++++ ++
Sbjct: 797 QIHSLSIEAKSKDVKI----EVLQNELDDVQLQFSEQSTLIRS-------LQSQLQNKES 845
Query: 223 ELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE 282
E+ +R+ + S + E E+ K LEK +++ L+Q +E+ + E
Sbjct: 846 EVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTE 905
Query: 283 ----------RFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEE 330
+ E K +L + LKE+ L S + + ++ED+E S L++
Sbjct: 906 ISFSMTEKMVQLNEEKFSLGVEIKTLKEQLN--LLSRAEEAKKEQVEEDNEVSSGLKQ 961
>gi|4503917 growth arrest-specific 8 [Homo sapiens]
Length = 478
Score = 49.3 bits (116), Expect = 6e-06
Identities = 52/246 (21%), Positives = 111/246 (45%), Gaps = 25/246 (10%)
Query: 117 EIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY------DLLGMEVELRE--MR 168
++ ++ V ++ + + ++KA + ++ K + D+ ++VEL+E +
Sbjct: 96 KVYKQKVKHLLYEHQNNLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQELA 155
Query: 169 TEAIARPLEINETEKV--MRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 226
+E + + L + TE++ MR + + +++ D + DE +L K E ++E ER
Sbjct: 156 SEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTELHEVE-ER 214
Query: 227 NRKRLETLQSVRPCFMDEYEKTEEELQKQY-DTYLEKFQNLTYLEQQLEDHHR----MEQ 281
++ TL M +E+ +++ Y D L + L++Q+ED + +E+
Sbjct: 215 KNGQIHTL-------MQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLER 267
Query: 282 ERFEEAKNTLCLIQ--NKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTA 339
E E + L K +EE + K +N + D I ++ ++ E+ L Q
Sbjct: 268 EMAEVSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWE 327
Query: 340 MEMLMQ 345
E+L Q
Sbjct: 328 HEVLEQ 333
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.5 bits (114), Expect = 1e-05
Identities = 70/331 (21%), Positives = 140/331 (42%), Gaps = 29/331 (8%)
Query: 84 KKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEI---VEEDVNKFKFDLGSKIADLKAA 140
K L Q G + + K+ + L ++ K EG + + + V K + +L + L +
Sbjct: 1234 KVLLQGKGDSEHKRKKVEAQLQE-LQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292
Query: 141 RQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTK 200
+S++T ++L L + +E+ E + L ++ K + Q+++ +
Sbjct: 1293 DSKSSKLTKDFSALESQLQ---DTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEE 1349
Query: 201 DLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYL 260
+ +N+ A L A++ K ++E + LET + V+ + E + +++ Y
Sbjct: 1350 EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYD 1409
Query: 261 EKFQNLTYLEQQLE------DHHRM-------EQERFEEAKNTLCLIQNKLKEEEKRLLK 307
+ + T L+Q+L+ DH R +Q++F++ I K EE R
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 308 SGSNDDSDI-----DIQEDDESDSELEERRLPKP-QTAMEMLMQGRPG-KRIVGTMQGGD 360
++ ++E E +ELE RL K +T ME LM + + V ++
Sbjct: 1470 EAREKETKALSLARALEEAMEQKAELE--RLNKQFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 361 SDDNEDSEESEIDMEDDDDEDDDLEDESISL 391
+ EE + +E+ +DE ED + L
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Score = 44.3 bits (103), Expect = 2e-04
Identities = 55/260 (21%), Positives = 112/260 (43%), Gaps = 24/260 (9%)
Query: 93 AVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGA 152
A+K++ ++ S + + +E K K DLG ++ LK + + T+
Sbjct: 1102 ALKKIRELESQISELQED--LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 153 SLYDLLGMEVEL--REMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDE 210
L EV + + + EA +I E + A++E+ Q+++TK + N+ +
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Query: 211 ANLEAK----------IEKRKLELERNRKRLET-LQSVRPCFMDEYEKTEEELQKQYDTY 259
LE + + + K + E RK++E LQ ++ F +E E+ EL +
Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF-NEGERVRTELADKVTKL 1278
Query: 260 LEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGS-----NDDS 314
+ N+T L Q + + F ++ L Q L+EE ++ L + D+
Sbjct: 1279 QVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK 1338
Query: 315 DI---DIQEDDESDSELEER 331
+ ++E++E+ LE++
Sbjct: 1339 NSFREQLEEEEEAKHNLEKQ 1358
Score = 42.7 bits (99), Expect = 6e-04
Identities = 65/294 (22%), Positives = 121/294 (41%), Gaps = 54/294 (18%)
Query: 129 DLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIA 188
DL +IA+L+A Q+A L M++ +E +A +E +K M +
Sbjct: 1059 DLSDQIAELQA--QIAE------------LKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 189 -IKEILTQVQKTKDLL-------NNVASDEANLEAKIEKRKLELE---RNRKRLETLQSV 237
I+E+ +Q+ + ++ L N + +L ++E K ELE + + L+S
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 238 RPCFMDEYEKTEEELQKQYDTYLEKF-----QNLTYLEQQLEDHHR-----------MEQ 281
R ++ +KT EE K ++ +++ Q + L +QLE R +E
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Query: 282 ERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAME 341
ER E A L+Q K E KR + + E + +EL + ++ K Q ++
Sbjct: 1225 ERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD-KVTKLQVELD 1283
Query: 342 MLMQGRPGKRIVGTMQGGDSDDN---EDSEESEIDMEDDDDEDDDLEDESISLS 392
+ G + DS + +D E ++D + + + +SLS
Sbjct: 1284 ---------NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLS 1328
Score = 38.5 bits (88), Expect = 0.011
Identities = 37/147 (25%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 156 DLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 215
+++ E EL ++R + +A + E E + + E L Q+Q+ + ++ L A
Sbjct: 846 EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKL-QLQEQLQAETELCAEAEELRA 904
Query: 216 KIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLED 275
++ +K ELE LE E+ EE Q + QN+ LE+QLE+
Sbjct: 905 RLTAKKQELEEICHDLEA----------RVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Query: 276 HHRMEQERFEEAKNTLCLIQNKLKEEE 302
Q+ E T ++ KL+EE+
Sbjct: 955 EESARQKLQLEKVTTEAKLK-KLEEEQ 980
Score = 36.2 bits (82), Expect = 0.056
Identities = 39/212 (18%), Positives = 86/212 (40%), Gaps = 25/212 (11%)
Query: 177 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQS 236
E+ ++++ + ++E+ TQ+++ +D L + LE ++ K + ER+
Sbjct: 1522 ELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERD--------- 1572
Query: 237 VRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQN 296
+ ++ EE +KQ + + +E +LED + K ++
Sbjct: 1573 -----LQGRDEQSEEKKKQL------VRQVREMEAELEDERKQRSMAVAARKK----LEM 1617
Query: 297 KLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAM-EMLMQGRPGKRIVGT 355
LK+ E + + N D I ++ + R L + + E+L Q + ++ + +
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKS 1677
Query: 356 MQGGDSDDNEDSEESEIDMEDDDDEDDDLEDE 387
M+ E+ +E E D+L DE
Sbjct: 1678 MEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
Score = 31.2 bits (69), Expect = 1.8
Identities = 71/358 (19%), Positives = 150/358 (41%), Gaps = 58/358 (16%)
Query: 51 DIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQA--DGYAVKELLKITSVLYNAM 108
D+ V+ E++R ++A K ++ N ++L + + + ++ L++ V A
Sbjct: 919 DLEARVEEEEERCQHLQA------EKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA- 971
Query: 109 KTKGMEGSEIVEEDVN----KFKFDLGSKIADL-----------KAARQLASEITSKGAS 153
K K +E +I+ ED N K K L +IA+ K+ +L ++ +
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD 1031
Query: 154 LYDLLGMEVELREMRTEAIARPLEINETEKVMRIA-----IKEILTQVQKTKDLLNNVAS 208
L + L E + R+ E R LE + T+ +IA I E+ Q+ K ++ L +
Sbjct: 1032 LEERLRREEKQRQ-ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090
Query: 209 ---DEA-----------NLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQK 254
+EA LE++I + + +LE R + + +E E + EL+
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
Query: 255 QYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDS 314
D+ + + + EQ++ + +++ EEAK IQ ++ + + + +
Sbjct: 1151 TLDSTAAQQELRSKREQEV---NILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQ 1207
Query: 315 DIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEI 372
++ + E + E + +++L+QG+ GDS+ E+++
Sbjct: 1208 TKRVKANLEKAKQTLENERGELANEVKVLLQGK-----------GDSEHKRKKVEAQL 1254
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 48.1 bits (113), Expect = 1e-05
Identities = 58/241 (24%), Positives = 107/241 (44%), Gaps = 38/241 (15%)
Query: 110 TKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRT 169
TK ME + + ED L +++ K A L+ + K S D+L + +T
Sbjct: 375 TKEMEKNTCIIED-------LKNELQRNKGASTLSQQTHMKIQSTLDIL-------KEKT 420
Query: 170 EAIARPLEINETEKVMRIAIKEILTQVQKTKDL------LNNVASDEANLEAKIEKRKLE 223
+ R E+ E + R KE++ +++ KD L + + N + +I+ R E
Sbjct: 421 KEAERTAELAEADA--REKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDRE 478
Query: 224 LERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLE--KFQNLTYLEQQ--------- 272
+E K + L+ F+DE E E + + T ++ +F+N +L+QQ
Sbjct: 479 IEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQIL 538
Query: 273 LEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERR 332
L++ +E+ER + K I+ +E KR SG + D+++ E+ + ER+
Sbjct: 539 LKEIESLEEERLDLKKK----IRQMAQERGKRSATSGLTTE-DLNLTENISQGDRISERK 593
Query: 333 L 333
L
Sbjct: 594 L 594
Score = 35.8 bits (81), Expect = 0.073
Identities = 60/275 (21%), Positives = 111/275 (40%), Gaps = 41/275 (14%)
Query: 80 KLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEE------DVNKFKFDLGSK 133
K+ +L V L +IT L MK K E +EE + KF+ L +K
Sbjct: 34 KVEVNELKSEKQENVIHLFRITQSL---MKMKAQEVELALEEVEKAGEEQAKFENQLKTK 90
Query: 134 IADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEIL 193
+ L+ ++A + S G L E+ E + E R LE E E + E L
Sbjct: 91 VMKLENELEMAQQ--SAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQL 148
Query: 194 TQVQKTKDLLNNVASDEANLEAKIEKRKLELERNR-------------KRLETLQSVRPC 240
L N ++ N + + E ++L+ + + + ETL S R
Sbjct: 149 A--------LRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRG- 199
Query: 241 FMDEYEKTEEELQKQYDT--YLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKL 298
++ + + +K Y+ YL++ Q LT +++E ++ ++ EE+ + K+
Sbjct: 200 --EDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEM----EKM 253
Query: 299 KEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRL 333
+E R+ D+ ID + + +L+ + L
Sbjct: 254 TDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQEL 288
Score = 35.8 bits (81), Expect = 0.073
Identities = 59/261 (22%), Positives = 114/261 (43%), Gaps = 31/261 (11%)
Query: 55 DVDTEQDRVFFIKAIAQFMAT-KAHI--KLNTKKLYQADGYAVKELLKITSVLYNAMKTK 111
D+ +++V +K + +F+ KA + KL + G + EL K ++ K
Sbjct: 2085 DLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLM-----KK 2139
Query: 112 GMEGSEIVEEDVNKFKFDLGS-KIADLKAARQ-LASEITSKGASLYDLLGMEVELREMRT 169
+E + E + K L S K+A+++ + L +E+ A L L M E + T
Sbjct: 2140 VVEKVQRENEQLKKASGILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTKGT 2199
Query: 170 EAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRK 229
E I I E E++ + +++K D + + NLE EK ++LE K
Sbjct: 2200 EKI-----IAENERLRK--------ELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGK 2246
Query: 230 RLETLQSVRPCFMDEYEKTEEEL--QKQYDTYLEKFQ-NLTYLEQQLEDHHRMEQERFEE 286
RL+ +S P K+ + + + Y+T L++ + ++ Q + D ++ +E E
Sbjct: 2247 RLQFAESRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEATER 2306
Query: 287 AKNTLCLIQNKLKEEEKRLLK 307
+ NK E+ ++ +K
Sbjct: 2307 EQKV-----NKYNEDLEQQIK 2322
Score = 32.7 bits (73), Expect = 0.62
Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 28/199 (14%)
Query: 161 EVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKD---LLNNVASDEANLEAKI 217
EV+L+ M+ + L E K + I+ I ++++ + L + +L AK
Sbjct: 1894 EVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKA 1953
Query: 218 EKRKLELERNRKRLE-TLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYL------- 269
+K KL L+R K T+ V E EK EEL+K+ L+ ++ Y+
Sbjct: 1954 DKEKLTLQRKLKTTGMTVDQVLGIRALESEKELEELKKRN---LDLENDILYMRAHQALP 2010
Query: 270 -EQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDD--ESDS 326
+ +ED H Q R+ +Q KL EK+ K + S I+ DD + +
Sbjct: 2011 RDSVVEDLHL--QNRY---------LQEKLHALEKQFSKDTYSKPSISGIESDDHCQREQ 2059
Query: 327 ELEERRLPKPQTAMEMLMQ 345
EL++ L +E+ Q
Sbjct: 2060 ELQKENLKLSSENIELKFQ 2078
Score = 31.2 bits (69), Expect = 1.8
Identities = 58/270 (21%), Positives = 105/270 (38%), Gaps = 42/270 (15%)
Query: 56 VDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEG 115
++ E+D IA+F + K+L + +KE+L+ + KG E
Sbjct: 617 IEKERDLERSRTVIAKFQNKLKELVEENKQLEEG----MKEILQAIKEMQKDPDVKGGET 672
Query: 116 SEIV---EEDVNKFKFDLGSKIADLKA-ARQLASEITSKGASLYDLLGMEVELREMRTEA 171
S I+ E VN + I D + ++T + L ELRE R EA
Sbjct: 673 SLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQ------ELRESRKEA 726
Query: 172 IARPLEINETEKVMRIAIKEILTQVQKTKDLL-----NNVASDEANLEAKIEKRKLEL-- 224
I N ++++ + +K + ++K LL +NV +L I +
Sbjct: 727 I------NYSQQLAKANLK--IDHLEKETSLLRQSEGSNVVFKGIDLPDGIAPSSASIIN 778
Query: 225 ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERF 284
+N + LQ ++ EK + L+ + Y KF + + + L + E+E +
Sbjct: 779 SQNEYLIHLLQE-----LENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETW 833
Query: 285 EEAKNTLCLIQNKLKEEEKRLLKSGSNDDS 314
+ T+ +EEKR L+ D+
Sbjct: 834 KTESKTI--------KEEKRKLEDQVQQDA 855
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 48.1 bits (113), Expect = 1e-05
Identities = 67/333 (20%), Positives = 140/333 (42%), Gaps = 33/333 (9%)
Query: 83 TKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQ 142
++K + D K LL ++ + +K EI + N+ + + A +KA +
Sbjct: 1650 SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLK-NQLEESEFTCAAAVKARKA 1708
Query: 143 LASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDL 202
+ EI + D+ + L E + E NE + + +++ ++K K
Sbjct: 1709 MEVEIEDLHLQIDDIAKAKTALEEQLSRL---QREKNEIQNRLEEDQEDMNELMKKHKAA 1765
Query: 203 LNNVASDEA---NLEAKIEKRKLELERNRKRLETLQS----VRPCFMDEYEKTEEELQ-K 254
+ + D A +L+A++E+ E + +++L+ LQS + +D+ + +E + +
Sbjct: 1766 VAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIR 1825
Query: 255 QYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDS 314
+ +T LE + + L + E+ E ++ +N+ KE+ KRL + +
Sbjct: 1826 ELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKE 1885
Query: 315 DIDIQEDDESDSELEERRLPKPQTAMEMLMQG-----RPGKRIVGTMQGG-----DSDDN 364
++ E+++ ++ L ++E Q + + +G +Q +SD+N
Sbjct: 1886 EMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDEN 1945
Query: 365 EDSEESEIDM-----------EDDDDEDDDLED 386
ED S DM E D D D +LED
Sbjct: 1946 EDLINSLQDMVTKYQKRKNKLEGDSDVDSELED 1978
Score = 41.6 bits (96), Expect = 0.001
Identities = 53/257 (20%), Positives = 110/257 (42%), Gaps = 43/257 (16%)
Query: 181 TEKVMRIA--IKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE----------LERNR 228
T+KV+ + +++I +Q K + L V +LEAK++ ++ E LE+ +
Sbjct: 1513 TQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAK 1572
Query: 229 KRLE-TLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNL-TYLEQQLEDHHRMEQERFEE 286
RLE ++ +R E E +EE+++ + +K + + LE++ ED ++ +E+ E
Sbjct: 1573 LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREK-RE 1631
Query: 287 AKNTLCLIQNKLK----EEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM 342
+ L + +++ E EKRL K D + + L Q ++
Sbjct: 1632 LEGKLATLSDQVNRRDFESEKRLRK-----------------DLKRTKALLADAQLMLDH 1674
Query: 343 LMQGRPGKRIVGTMQGGDSDDN-------EDSEESEIDMEDDDDEDDDLEDESISLSPTK 395
L P KR + ++ + + + E+++ED + DD+ +L
Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
Query: 396 PNRRVRKSEPLDESDND 412
+ K+E + + D
Sbjct: 1735 SRLQREKNEIQNRLEED 1751
>gi|217035164 coiled-coil domain containing 27 [Homo sapiens]
Length = 656
Score = 48.1 bits (113), Expect = 1e-05
Identities = 51/197 (25%), Positives = 87/197 (44%), Gaps = 23/197 (11%)
Query: 136 DLKAARQLASEITSKGASLYDLLGM-EVELREMRTEAIARPLEINETEKVMRIAIKEILT 194
+L+A R S T ASL + E +LR++ TE NET ++ ++E
Sbjct: 428 NLEATRTRYSLATGVIASLQQQVDFQETQLRKINTE--------NET---LQKELRERRQ 476
Query: 195 QVQKTKDLLNNVASDEANLEAK--IEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEEL 252
Q+Q D +N+ D+ + E IEK L + LE + R C + E + +L
Sbjct: 477 QLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERKLTKRDCVISELDTKVSQL 536
Query: 253 QKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLL------ 306
Q+Q + Q L++ L+ M Q+ + + L Q++L+ +++
Sbjct: 537 QEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESSQSRLERLRNKIIQATFSI 596
Query: 307 ---KSGSNDDSDIDIQE 320
KS +N+ SD DI E
Sbjct: 597 SGTKSLANEISDNDILE 613
Score = 29.3 bits (64), Expect = 6.8
Identities = 45/201 (22%), Positives = 77/201 (38%), Gaps = 29/201 (14%)
Query: 226 RNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLE---QQLEDHHRMEQE 282
R R++ +TL V + + + EK L+ LE Q+ ++ + QE
Sbjct: 201 RKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQE 260
Query: 283 RFEEAKNTL-CLIQNK------------------LKEEEKRLLKSGSNDDSDID----IQ 319
E K L CL++ K LK LLK+ S + ++ +Q
Sbjct: 261 EREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQ 320
Query: 320 EDDESDSELEERRLPKPQTAMEMLMQGRP-GKRIVGTMQGGDSDDNEDSEESEIDMEDDD 378
E+ + +E L + + ++G P G G G + E SE + E++
Sbjct: 321 EESAAPERGKEPDLGGGEE--DEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEG 378
Query: 379 DEDDDLEDESISLSPTKPNRR 399
D D+D E+ + P RR
Sbjct: 379 DRDEDSEERELPEEEEIPRRR 399
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 47.8 bits (112), Expect = 2e-05
Identities = 55/291 (18%), Positives = 126/291 (43%), Gaps = 19/291 (6%)
Query: 76 KAHIKLNTKKLYQADGYAVKELLKITSVLYNA----MKTKGMEGSEIVEEDVNKFKFDLG 131
K + +KL + + LLK +++ A M K +E ++ + ++ L
Sbjct: 635 KQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELES----LS 690
Query: 132 SKIADLKAARQLASEITSKGASLYDLLGMEVELR--------EMRTEAIARPLEIN--ET 181
S+++++ AR E S D + E+E + + + ++I + E++ T
Sbjct: 691 SELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRT 750
Query: 182 EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCF 241
EK ++ I ++ +++ L + NLEA I++ + EL++ +L+ QS +
Sbjct: 751 EKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAT 810
Query: 242 MDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEE 301
++ + EE+L + L+ L +Q+ + +++ E +Q+ +++
Sbjct: 811 HEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQL 870
Query: 302 EKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAME-MLMQGRPGKR 351
EK+ + S + E D E+ + + E M++Q R G++
Sbjct: 871 EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQK 921
Score = 43.9 bits (102), Expect = 3e-04
Identities = 52/222 (23%), Positives = 101/222 (45%), Gaps = 20/222 (9%)
Query: 96 ELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSK--GAS 153
+LL +N ++ K + G+E ++ + K L + L+ Q EI K
Sbjct: 1916 KLLSNMEAQHNDLEFK-LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQE 1974
Query: 154 LYDLLGMEVELREMRTEAIARPL------EINETEKVMRIAIKEILTQVQKTK-DLLNNV 206
+ + E E E++ + + L ++ + E+ + + IKE + + Q+ + +LL +
Sbjct: 1975 REEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESH 2034
Query: 207 ASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMD----EYEKTEEELQKQYDTYLEK 262
+ L KI ++ +L+R KR E + R M + + EELQK+Y LE+
Sbjct: 2035 QEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ 2094
Query: 263 FQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKR 304
+N D+ + + + + A+ T + +KLKE+E R
Sbjct: 2095 EEN------PGNDNVTIMELQTQLAQKTTLISDSKLKEQEFR 2130
Score = 40.8 bits (94), Expect = 0.002
Identities = 54/271 (19%), Positives = 121/271 (44%), Gaps = 35/271 (12%)
Query: 94 VKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGAS 153
++EL KI L+ A KTK + + + + + D G IA+ K RQ+ + K
Sbjct: 327 LQELEKIKD-LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETK--RQMHETLEMKEEE 383
Query: 154 LYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDE--- 210
+ L +++M T+ + ++E+ +++ L+ QKT++ + ++
Sbjct: 384 IAQLRS---RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 440
Query: 211 -ANLEAKIEKRKLELERNRKRL-------------ETLQSVRPCFMDEYEKTEEELQKQY 256
+E E+ ++ L++ R+ E + ++ E + E+EL K+
Sbjct: 441 IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKL 500
Query: 257 DTYLEKFQN--LTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDS 314
T +FQ LE+ ++ ++ QE+ E + +L L +L+ ++K +L N
Sbjct: 501 QTREREFQEQMKVALEKSQSEYLKISQEK--EQQESLAL--EELELQKKAILTESENKLR 556
Query: 315 DIDIQEDDESDSELEERRLPKPQTAMEMLMQ 345
D+ + ++E R+ + ++++E +Q
Sbjct: 557 DL------QQEAETYRTRILELESSLEKSLQ 581
Score = 39.7 bits (91), Expect = 0.005
Identities = 50/258 (19%), Positives = 105/258 (40%), Gaps = 24/258 (9%)
Query: 160 MEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEK 219
M E+ ++ E + + +NE ++ Q+++ +N++A DE L+A +EK
Sbjct: 1090 MNKEITWLKEEGVKQDTTLNELQE-----------QLKQKSAHVNSLAQDETKLKAHLEK 1138
Query: 220 RKLELERNRKRLETLQS---VRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDH 276
+++L ++ K LQ +E ++ EL + T E+FQ+L ++
Sbjct: 1139 LEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKS 1198
Query: 277 HRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDID----------IQEDDESDS 326
+ F++ L + + ++ + LL++ +N+ +I I +
Sbjct: 1199 LEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTT 1258
Query: 327 ELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLED 386
+++E L K T E+ Q R T+ EE E ++ + + L
Sbjct: 1259 KVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVT 1318
Query: 387 ESISLSPTKPNRRVRKSE 404
E +L N++ SE
Sbjct: 1319 EKEALQKEGGNQQQAASE 1336
Score = 35.0 bits (79), Expect = 0.12
Identities = 56/193 (29%), Positives = 84/193 (43%), Gaps = 38/193 (19%)
Query: 146 EITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNN 205
E+TSK L L +++ R TE LE N EK K L Q + LL+N
Sbjct: 1876 ELTSKYEKLQAL--QQMDGRNKPTEL----LEENTEEKS-----KSHLVQPK----LLSN 1920
Query: 206 VASDEANLEAKI-----EKRKL--ELERNRKRLETL----QSVRPCFMDEYEKTEEELQK 254
+ + +LE K+ EK+KL E+ R +K L L Q EY++ EE K
Sbjct: 1921 MEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIK 1980
Query: 255 QYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE-----------EEK 303
Q LE N T L+Q + + + ++ +E + T+ NK +E E
Sbjct: 1981 QEQEDLELKHNST-LKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETN 2039
Query: 304 RLLKSGSNDDSDI 316
+LLK + D D+
Sbjct: 2040 QLLKKIAEKDDDL 2052
Score = 32.3 bits (72), Expect = 0.81
Identities = 57/300 (19%), Positives = 130/300 (43%), Gaps = 69/300 (23%)
Query: 56 VDTEQDRVFFIKAIAQFMATKAHI--KLNTKKLYQADGYAVKELLKITSVLYNAMKTKGM 113
+D E +R+ K +A+ A K + +L+ K+ V++L++ + M+ K
Sbjct: 829 LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQ------VQDLMQQLEKQNSEMEQKVK 882
Query: 114 EGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIA 173
+++ E SK+ D ++ +I L + M +++RE + + I
Sbjct: 883 SLTQVYE-----------SKLEDGNKEQEQTKQI------LVEKENMILQMREGQKKEI- 924
Query: 174 RPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLET 233
EILTQ K+ ++ ++E + K +++K+E + +K E
Sbjct: 925 -----------------EILTQKLSAKEDSIHILNEEYETKFKNQEKKME-KVKQKAKEM 966
Query: 234 LQSVRPCFMDEYEKTEEEL----------QKQYDT-YLEKFQ----NLTYLEQQLEDHHR 278
++++ +D+ K ++EL +KQ++ LE Q ++ +LE + +
Sbjct: 967 QETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK 1026
Query: 279 MEQERF-----EEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRL 333
+ E E + + + + KL ++ + L + +I +QE ++ +EL+++ L
Sbjct: 1027 EQIESLTEVHRRELNDVISIWEKKLNQQAEEL-----QEIHEIQLQEKEQEVAELKQKIL 1081
Score = 31.6 bits (70), Expect = 1.4
Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 25/192 (13%)
Query: 214 EAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQL 273
+ +I K EL++ KR + C E E + +++K+ + ++ T +L
Sbjct: 1478 DEQINLLKEELDQQNKRFD-------CLKGEMEDDKSKMEKKESNLETELKSQTARIMEL 1530
Query: 274 EDHHRMEQERFE-EAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERR 332
EDH + Q+ E E+ N + N+ K+ E + L ++ +E D E EE+
Sbjct: 1531 EDH--ITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELG-EEKDNRVKEAEEKI 1587
Query: 333 LPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLS 392
L M + K+ + E + ++ ++E LED S S
Sbjct: 1588 LTLENQVYSMKAELETKKK--------------ELEHVNLSVKSKEEELKALEDRLESES 1633
Query: 393 PTKPNRRVRKSE 404
K RK+E
Sbjct: 1634 AAKLAELKRKAE 1645
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 47.4 bits (111), Expect = 2e-05
Identities = 65/307 (21%), Positives = 131/307 (42%), Gaps = 25/307 (8%)
Query: 108 MKTKGMEGSEIVEEDVNKFKFD---LGSKIADLKAARQLASEITSKGASLYDLLGMEVEL 164
+K E E ++ NK D G K + L +I LY + +
Sbjct: 399 LKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 458
Query: 165 REMRTEAIARPLEINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE 223
+ + I EIN EK +R+ K I V + LN++ ++ A L +++EK K
Sbjct: 459 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 518
Query: 224 LERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ------QLEDHH 277
ER +E+L S ++EY + E +K + L + +++ E+ QL D +
Sbjct: 519 KERLEAEVESLHSSLATAINEYNEIVE--RKDLELVLWRADDVSRHEKMGSNISQLTDKN 576
Query: 278 RMEQERFEEAKNTLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDD---------ESDSE 327
+ E+ +A+ ++ KL+E L K+ + +D+++ + E
Sbjct: 577 ELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGE 636
Query: 328 LEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDL 384
+E + Q ++E ++ + + ++ Q D+ D++E I++ D + ++D L
Sbjct: 637 AKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLL 696
Query: 385 EDESISL 391
E+ + L
Sbjct: 697 EERNKEL 703
Score = 38.1 bits (87), Expect = 0.015
Identities = 68/282 (24%), Positives = 119/282 (42%), Gaps = 36/282 (12%)
Query: 41 WLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQ-ADGYAVKELLK 99
W K+ Q +I P+ E+ R F + I+ T I+ ++L + A GY K+ L+
Sbjct: 763 WTSKKKLFQVEIQPEEKHEEFRKLF-ELISLLNYTADQIRKKNRELEEEATGY--KKCLE 819
Query: 100 ITSVLYNAMKTKGMEGSEIVEEDVNKFKF---DLGSKIADLKAARQLASEITSKGASLYD 156
+T + NA + + D K L K DL A ++ S A +
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879
Query: 157 LLGMEV-ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 215
+L E+ +R ++ + + EK ++ +E+L +L ++ D L
Sbjct: 880 VLHQELLSMRNVQEKC-------EKLEKDKKMLEEEVL-------NLKTHMEKDMVEL-G 924
Query: 216 KIEKRKLEL-ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLE 274
K+++ K EL ER + +E L+ + EYEK E+L K L+K + LT + + +
Sbjct: 925 KLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK-KELTLKDVECK 983
Query: 275 --------DHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 308
+ E E F+EA N + K+L+KS
Sbjct: 984 FSKMKTAYEEVTTELEEFKEAFAGAVKANNSM---SKKLMKS 1022
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 47.4 bits (111), Expect = 2e-05
Identities = 65/307 (21%), Positives = 131/307 (42%), Gaps = 25/307 (8%)
Query: 108 MKTKGMEGSEIVEEDVNKFKFD---LGSKIADLKAARQLASEITSKGASLYDLLGMEVEL 164
+K E E ++ NK D G K + L +I LY + +
Sbjct: 292 LKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 351
Query: 165 REMRTEAIARPLEINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE 223
+ + I EIN EK +R+ K I V + LN++ ++ A L +++EK K
Sbjct: 352 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 411
Query: 224 LERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ------QLEDHH 277
ER +E+L S ++EY + E +K + L + +++ E+ QL D +
Sbjct: 412 KERLEAEVESLHSSLATAINEYNEIVE--RKDLELVLWRADDVSRHEKMGSNISQLTDKN 469
Query: 278 RMEQERFEEAKNTLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDD---------ESDSE 327
+ E+ +A+ ++ KL+E L K+ + +D+++ + E
Sbjct: 470 ELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGE 529
Query: 328 LEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDL 384
+E + Q ++E ++ + + ++ Q D+ D++E I++ D + ++D L
Sbjct: 530 AKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLL 589
Query: 385 EDESISL 391
E+ + L
Sbjct: 590 EERNKEL 596
Score = 38.1 bits (87), Expect = 0.015
Identities = 68/282 (24%), Positives = 119/282 (42%), Gaps = 36/282 (12%)
Query: 41 WLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQ-ADGYAVKELLK 99
W K+ Q +I P+ E+ R F + I+ T I+ ++L + A GY K+ L+
Sbjct: 656 WTSKKKLFQVEIQPEEKHEEFRKLF-ELISLLNYTADQIRKKNRELEEEATGY--KKCLE 712
Query: 100 ITSVLYNAMKTKGMEGSEIVEEDVNKFKF---DLGSKIADLKAARQLASEITSKGASLYD 156
+T + NA + + D K L K DL A ++ S A +
Sbjct: 713 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 772
Query: 157 LLGMEV-ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 215
+L E+ +R ++ + + EK ++ +E+L +L ++ D L
Sbjct: 773 VLHQELLSMRNVQEKC-------EKLEKDKKMLEEEVL-------NLKTHMEKDMVEL-G 817
Query: 216 KIEKRKLEL-ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLE 274
K+++ K EL ER + +E L+ + EYEK E+L K L+K + LT + + +
Sbjct: 818 KLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK-KELTLKDVECK 876
Query: 275 --------DHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 308
+ E E F+EA N + K+L+KS
Sbjct: 877 FSKMKTAYEEVTTELEEFKEAFAGAVKANNSM---SKKLMKS 915
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 47.4 bits (111), Expect = 2e-05
Identities = 65/307 (21%), Positives = 131/307 (42%), Gaps = 25/307 (8%)
Query: 108 MKTKGMEGSEIVEEDVNKFKFD---LGSKIADLKAARQLASEITSKGASLYDLLGMEVEL 164
+K E E ++ NK D G K + L +I LY + +
Sbjct: 399 LKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 458
Query: 165 REMRTEAIARPLEINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE 223
+ + I EIN EK +R+ K I V + LN++ ++ A L +++EK K
Sbjct: 459 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 518
Query: 224 LERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ------QLEDHH 277
ER +E+L S ++EY + E +K + L + +++ E+ QL D +
Sbjct: 519 KERLEAEVESLHSSLATAINEYNEIVE--RKDLELVLWRADDVSRHEKMGSNISQLTDKN 576
Query: 278 RMEQERFEEAKNTLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDD---------ESDSE 327
+ E+ +A+ ++ KL+E L K+ + +D+++ + E
Sbjct: 577 ELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGE 636
Query: 328 LEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDL 384
+E + Q ++E ++ + + ++ Q D+ D++E I++ D + ++D L
Sbjct: 637 AKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLL 696
Query: 385 EDESISL 391
E+ + L
Sbjct: 697 EERNKEL 703
Score = 38.1 bits (87), Expect = 0.015
Identities = 68/282 (24%), Positives = 119/282 (42%), Gaps = 36/282 (12%)
Query: 41 WLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQ-ADGYAVKELLK 99
W K+ Q +I P+ E+ R F + I+ T I+ ++L + A GY K+ L+
Sbjct: 763 WTSKKKLFQVEIQPEEKHEEFRKLF-ELISLLNYTADQIRKKNRELEEEATGY--KKCLE 819
Query: 100 ITSVLYNAMKTKGMEGSEIVEEDVNKFKF---DLGSKIADLKAARQLASEITSKGASLYD 156
+T + NA + + D K L K DL A ++ S A +
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879
Query: 157 LLGMEV-ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 215
+L E+ +R ++ + + EK ++ +E+L +L ++ D L
Sbjct: 880 VLHQELLSMRNVQEKC-------EKLEKDKKMLEEEVL-------NLKTHMEKDMVEL-G 924
Query: 216 KIEKRKLEL-ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLE 274
K+++ K EL ER + +E L+ + EYEK E+L K L+K + LT + + +
Sbjct: 925 KLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK-KELTLKDVECK 983
Query: 275 --------DHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 308
+ E E F+EA N + K+L+KS
Sbjct: 984 FSKMKTAYEEVTTELEEFKEAFAGAVKANNSM---SKKLMKS 1022
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 47.0 bits (110), Expect = 3e-05
Identities = 70/322 (21%), Positives = 127/322 (39%), Gaps = 58/322 (18%)
Query: 111 KGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY--------------- 155
K M E +EE ++ K D L R L +I+S+ L
Sbjct: 115 KRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDK 174
Query: 156 --DLLGMEVE-LREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEAN 212
L E+E L+ + ++ +NE EK IKE+ ++++ K + + + +N
Sbjct: 175 TEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASN 234
Query: 213 LEAKIEKRKLELERNRKRLET-LQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ 271
LERN R+E + S P ++E +K YL++ +N T +
Sbjct: 235 -----------LERNDLRIEDGISSTLP--------SKESRRKGGLDYLKQVENETRNKS 275
Query: 272 QLEDHHRMEQERFEEAKNTLCLIQNKLK-----EEEKRLLKSGSNDDSDIDIQEDDESD- 325
+ E + E + ++ + ++ ++K EEE + +KS +ND D + E +++
Sbjct: 276 ENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKL 335
Query: 326 --SELEERRLP-KPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDD 382
S+LEE +L K Q +E G ++G D+ + E
Sbjct: 336 LASQLEEIKLQIKKQKELEN-----------GEVEGEDAFLSSKGRHERTKFRGHGSEAS 384
Query: 383 DLEDESISLSPTKPNRRVRKSE 404
+ + LSP R+R E
Sbjct: 385 VSKHTARELSPQHKRERLRNRE 406
Score = 32.3 bits (72), Expect = 0.81
Identities = 56/305 (18%), Positives = 126/305 (41%), Gaps = 34/305 (11%)
Query: 127 KFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMR 186
+F L S L + + L DL ++ + +A +E+ ++V+R
Sbjct: 17 RFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAE-IEVLR-QRVLR 74
Query: 187 IAIKEILTQVQKTKDL---LNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCF-- 241
I K+ ++++ +DL + +E NL ++ K E+ER +KR+ L+ + F
Sbjct: 75 IEGKD--EEIKRAEDLCRLMKEKLEEEENLTREL---KSEIERLQKRMAELEKLEEAFSR 129
Query: 242 -----------MDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKN- 289
++E +++ + + K + L E +L+ + E+ K+
Sbjct: 130 SKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEKLKSL 189
Query: 290 TLCLI------QNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEML 343
TL + K KE EK + + + + + D ++ ER + + +
Sbjct: 190 TLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISST 249
Query: 344 MQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKS 403
+ + +R G + +NE +SE + ++ + ED+ ++D + + K +++
Sbjct: 250 LPSKESRR-KGGLDYLKQVENETRNKSE-NEKNRNQEDNKVKDLNQEIEKLK--TQIKHF 305
Query: 404 EPLDE 408
E L+E
Sbjct: 306 ESLEE 310
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 47.0 bits (110), Expect = 3e-05
Identities = 70/322 (21%), Positives = 127/322 (39%), Gaps = 58/322 (18%)
Query: 111 KGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY--------------- 155
K M E +EE ++ K D L R L +I+S+ L
Sbjct: 115 KRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDK 174
Query: 156 --DLLGMEVE-LREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEAN 212
L E+E L+ + ++ +NE EK IKE+ ++++ K + + + +N
Sbjct: 175 TEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASN 234
Query: 213 LEAKIEKRKLELERNRKRLET-LQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ 271
LERN R+E + S P ++E +K YL++ +N T +
Sbjct: 235 -----------LERNDLRIEDGISSTLP--------SKESRRKGGLDYLKQVENETRNKS 275
Query: 272 QLEDHHRMEQERFEEAKNTLCLIQNKLK-----EEEKRLLKSGSNDDSDIDIQEDDESD- 325
+ E + E + ++ + ++ ++K EEE + +KS +ND D + E +++
Sbjct: 276 ENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKL 335
Query: 326 --SELEERRLP-KPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDD 382
S+LEE +L K Q +E G ++G D+ + E
Sbjct: 336 LASQLEEIKLQIKKQKELEN-----------GEVEGEDAFLSSKGRHERTKFRGHGSEAS 384
Query: 383 DLEDESISLSPTKPNRRVRKSE 404
+ + LSP R+R E
Sbjct: 385 VSKHTARELSPQHKRERLRNRE 406
Score = 32.3 bits (72), Expect = 0.81
Identities = 56/305 (18%), Positives = 126/305 (41%), Gaps = 34/305 (11%)
Query: 127 KFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMR 186
+F L S L + + L DL ++ + +A +E+ ++V+R
Sbjct: 17 RFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAE-IEVLR-QRVLR 74
Query: 187 IAIKEILTQVQKTKDL---LNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCF-- 241
I K+ ++++ +DL + +E NL ++ K E+ER +KR+ L+ + F
Sbjct: 75 IEGKD--EEIKRAEDLCRLMKEKLEEEENLTREL---KSEIERLQKRMAELEKLEEAFSR 129
Query: 242 -----------MDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKN- 289
++E +++ + + K + L E +L+ + E+ K+
Sbjct: 130 SKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEKLKSL 189
Query: 290 TLCLI------QNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEML 343
TL + K KE EK + + + + + D ++ ER + + +
Sbjct: 190 TLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISST 249
Query: 344 MQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKS 403
+ + +R G + +NE +SE + ++ + ED+ ++D + + K +++
Sbjct: 250 LPSKESRR-KGGLDYLKQVENETRNKSE-NEKNRNQEDNKVKDLNQEIEKLK--TQIKHF 305
Query: 404 EPLDE 408
E L+E
Sbjct: 306 ESLEE 310
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/184 (20%), Positives = 86/184 (46%), Gaps = 9/184 (4%)
Query: 158 LGMEVELREMRTEAIARPLEINETEK-VMRIAIKEILTQVQKTKDLLNNVASDEANLEAK 216
L + +E E + IA L+ E E ++ ++ + ++Q +++ V D N +A+
Sbjct: 2124 LRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE 2183
Query: 217 IEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDH 276
+E K ++E + L+ + E E +++Q++ E + L+ + LE+
Sbjct: 2184 VETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEK 2243
Query: 277 HRMEQERFEEAKNTLCLIQNKLKEEEKRL--------LKSGSNDDSDIDIQEDDESDSEL 328
+ E + EE+K + ++QN+LKE + + + + D I+E+ + + +
Sbjct: 2244 EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSI 2303
Query: 329 EERR 332
E+ R
Sbjct: 2304 EKLR 2307
Score = 38.1 bits (87), Expect = 0.015
Identities = 46/211 (21%), Positives = 91/211 (43%), Gaps = 26/211 (12%)
Query: 117 EIVEEDVNKFKFDLGSK---IADLKAARQ-LASEITSKGASLY----DLLGMEVELREMR 168
+I + D N FD S + LKA Q L ++I L ++ G + +E++
Sbjct: 260 QIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQ 319
Query: 169 TEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNR 228
+ +E+ E EKV+ E++ +T + ++ LE K++K +L R
Sbjct: 320 LQLEKAKVELIEKEKVLNKCRDELV----RTTAQYDQASTKYTALEQKLKKLTEDLSCQR 375
Query: 229 KRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQ-----------NLTYLEQQLEDHH 277
+ E S R + ++ E+E Q++ FQ LT QQ ++ H
Sbjct: 376 QNAE---SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMH 432
Query: 278 RMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 308
+ Q ++ + ++N L+E +++L ++
Sbjct: 433 NVLQAELDKLTSVKQQLENNLEEFKQKLCRA 463
Score = 37.0 bits (84), Expect = 0.033
Identities = 37/179 (20%), Positives = 83/179 (46%), Gaps = 9/179 (5%)
Query: 161 EVELREMRTEAIARPLEINETEKVMRIAIKEILT-QVQKTKDLLNNVASDEANLEAKIEK 219
EVE + + E + + L E + V + KE LT ++QK ++ ++ + ++ E +++
Sbjct: 2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Query: 220 RKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRM 279
++ E + +++ T + + E + L + K QNL+ + LE
Sbjct: 2425 KEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQ 2484
Query: 280 EQERFEEAKNTLCLIQNKLK------EEEKRLLKSGSNDDSDI--DIQEDDESDSELEE 330
+ +EAKN ++Q+ + E+ K+ L+ + S + IQ+ ++ S+L +
Sbjct: 2485 LLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ 2543
Score = 36.2 bits (82), Expect = 0.056
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 27/166 (16%)
Query: 177 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQS 236
+INE E ++ KE+ QV K ++L + ++EK K+EL K L +
Sbjct: 293 KINELELRLQGHEKEMKGQVNKFQEL-----------QLQLEKAKVELIEKEKVLNKCR- 340
Query: 237 VRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQN 296
DE +T QYD K+ T LEQ+L+ + + A++ C ++
Sbjct: 341 ------DELVRTTA----QYDQASTKY---TALEQKLKKLTEDLSCQRQNAESARCSLEQ 387
Query: 297 KLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM 342
K+KE+EK + S Q D+ +++ R + Q A M
Sbjct: 388 KIKEKEKEFQEELSRQQR--SFQTLDQECIQMKARLTQELQQAKNM 431
Score = 35.0 bits (79), Expect = 0.12
Identities = 42/177 (23%), Positives = 71/177 (40%), Gaps = 24/177 (13%)
Query: 189 IKEILTQVQKTKDLLNNVASDEAN----LEAKIEKRKLELERNRKRLETLQSVRPCFMD- 243
I + Q+Q + L++ ++ E E +E R L +E +K ++ LQS D
Sbjct: 2524 ISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQK-IQVLQSKNASLQDT 2582
Query: 244 ------EYEKTEEELQ---KQYDTYLEKFQNLTYLEQQLE-DHHRMEQERFEEAKNTLCL 293
Y+ E EL+ +++EK +T E +L+ + H M Q+ E
Sbjct: 2583 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAE-------- 2634
Query: 294 IQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGK 350
+Q +L E+ RL +I +D + LE L K M + GK
Sbjct: 2635 LQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2691
Score = 34.7 bits (78), Expect = 0.16
Identities = 57/235 (24%), Positives = 100/235 (42%), Gaps = 39/235 (16%)
Query: 74 ATKAH--IKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLG 131
A K H + L+T K Y+ + +E K+TS K + + ++ + + K +L
Sbjct: 2706 AEKKHQALLLDTNKQYEVEIQTYRE--KLTS------KEECLSSQKLEIDLLKSSKEELN 2757
Query: 132 SKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKE 191
+ LKA Q+ E+ + D L +L++ A + M++ IK
Sbjct: 2758 NS---LKATTQILEELKK---TKMDNLKYVNQLKKENERAQGK----------MKLLIKS 2801
Query: 192 ILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEE 251
Q+++ K++L S L+A EK+K + K E ++ E ++T EE
Sbjct: 2802 C-KQLEEEKEILQKELSQ---LQAAQEKQKTGTVMDTKVDELTTEIK-----ELKETLEE 2852
Query: 252 LQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLL 306
K+ D YL+K+ +L ++LE +E E LC Q+K LL
Sbjct: 2853 KTKEADEYLDKYCSLLISHEKLE----KAKEMLETQVAHLCSQQSKQDSRGSPLL 2903
Score = 33.9 bits (76), Expect = 0.28
Identities = 40/177 (22%), Positives = 82/177 (46%), Gaps = 14/177 (7%)
Query: 109 KTKGMEGS-EIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREM 167
K + +EG + ++++ + +F L S A L+ +Q ++G +L +
Sbjct: 19 KIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNL--------KRENQ 70
Query: 168 RTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERN 227
R I LE + + + +KE +QV + LN+ LE ++++ K ELER+
Sbjct: 71 RLMEICESLEKTKQKISHELQVKE--SQVNFQEGQLNSGKKQIEKLEQELKRCKSELERS 128
Query: 228 RKRLETLQ-SVRPCFMDEYEKTEEELQKQYDTYLEKFQNL-TYLEQQLEDHHRMEQE 282
++ ++ S+ PC + T QY + K+++L +++E+ R+E E
Sbjct: 129 QQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSG-SKYEDLKEKYNKEVEERKRLEAE 184
Score = 33.9 bits (76), Expect = 0.28
Identities = 38/192 (19%), Positives = 77/192 (40%), Gaps = 16/192 (8%)
Query: 76 KAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFD-LGSKI 134
+A +K + L Q+ +A + K TS +T + E + + N + L +
Sbjct: 506 EAELKNIKQCLNQSQNFAEEMKAKNTS-----QETMLRDLQEKINQQENSLTLEKLKLAV 560
Query: 135 ADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILT 194
ADL+ R + ++ K + L ++ E ++A+ LE+ + E
Sbjct: 561 ADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKE----------YE 610
Query: 195 QVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQK 254
++++ K L + S+ L ++E K L+ LET + EY + L+
Sbjct: 611 ELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEM 670
Query: 255 QYDTYLEKFQNL 266
+ + +NL
Sbjct: 671 DRENLSVEIRNL 682
Score = 33.5 bits (75), Expect = 0.36
Identities = 67/325 (20%), Positives = 143/325 (44%), Gaps = 27/325 (8%)
Query: 94 VKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGAS 153
++EL K +L +++K +++ E ++ K ++ S I+ K R++ E+T + +
Sbjct: 927 IQELKKSNHLLEDSLKEL-----QLLSETLSLEKKEMSSIISLNK--REI-EELTQENGT 978
Query: 154 LYDL---LGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDE 210
L ++ L E ++E+ A I+E EK +I E+ Q ++ K +L +
Sbjct: 979 LKEINASLNQEKMNLIQKSESFAN--YIDEREK----SISELSDQYKQEKLILLQRCEET 1032
Query: 211 AN-LEAKIEKRKLELERNRK---RLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNL 266
N E +K K E+N K L S+ +E E+ +E K++ +L K L
Sbjct: 1033 GNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTK---L 1089
Query: 267 TYLEQQLEDHHRMEQERFEEA-KNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESD 325
+ E++ + +E E ++A ++ + QN K E L + + + + + +D
Sbjct: 1090 AFAEER-NQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVND 1148
Query: 326 SELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLE 385
E +L K Q + I +++ +S+ N+ + + ++D+E + D
Sbjct: 1149 LLQENEQLMKVMKTKHE-CQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYN 1207
Query: 386 DESISLSPTKPNRRVRKSEPLDESD 410
+ + L N+ ++ E E +
Sbjct: 1208 AQLVQLEAMLRNKELKLQESEKEKE 1232
Score = 30.8 bits (68), Expect = 2.3
Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 10/132 (7%)
Query: 189 IKEILTQVQK-TKDLLNNVASDEA---NLEAKIEKRK--LELERNRKRLETLQSVRPCFM 242
IK+ L Q Q +++ S E +L+ KI +++ L LE+ + + L+ R C
Sbjct: 512 IKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQ 571
Query: 243 DEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEE 302
D +K E +++ D + + L LE ++++ +EE K L E E
Sbjct: 572 DLLKKREHHIEQLNDKLSKTEKESKALLSALE----LKKKEYEELKEEKTLFSCWKSENE 627
Query: 303 KRLLKSGSNDDS 314
K L + S ++
Sbjct: 628 KLLTQMESEKEN 639
Score = 30.8 bits (68), Expect = 2.3
Identities = 62/307 (20%), Positives = 130/307 (42%), Gaps = 49/307 (15%)
Query: 108 MKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREM 167
++T + SE++++ K L K+ L+ Q S + + L E EL
Sbjct: 2016 LQTLSSDVSELLKD-----KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVK 2070
Query: 168 RTEAIARPLEINETEKV-MRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 226
+E++ L ++ EK+ + A++ L + + L++ + L IEK ++ +E
Sbjct: 2071 ESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEA 2130
Query: 227 NRKR-------LETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRM 279
+ K+ L+ + D+ E E ELQ E+ Q L L+ ++ +
Sbjct: 2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMS-----EENQELVILD---AENSKA 2182
Query: 280 EQE----RFEEAKNTLCLIQNKL------KEEEKRLLKSGSNDDSDID---------IQE 320
E E + EE +L + + L KE + ++ S++D ++E
Sbjct: 2183 EVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEE 2242
Query: 321 DDESDSELEERRLPKPQTAMEMLM-QGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDD 379
++++ +++E + +TA+EML Q + V + G D E + +E ++ +
Sbjct: 2243 KEQAEIQIKE----ESKTAVEMLQNQLKELNEAVAALCG----DQEIMKATEQSLDPPIE 2294
Query: 380 EDDDLED 386
E+ L +
Sbjct: 2295 EEHQLRN 2301
>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
isoform 2 [Homo sapiens]
Length = 470
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/244 (22%), Positives = 105/244 (43%), Gaps = 26/244 (10%)
Query: 161 EVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKR 220
E E R+ + E + +I + +K+ RI ++ L K K L DE L+ + + +
Sbjct: 230 EEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAK 289
Query: 221 KLELE----------------RNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQ 264
KL+ E R+ L+ + RP DE + E +++Y+ E+
Sbjct: 290 KLDKENLSDERASGQSCTLPKRSDSELKDEKPKRP--EDESGRDYREREREYERDQERIL 347
Query: 265 NLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDES 324
++ E+ R ++ER+E+ K T + ++K+E+ L G +S I +++
Sbjct: 348 RERERLKRQEEERRRQKERYEKEK-TFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKT 406
Query: 325 DSELE----ERRLPKPQTAMEMLMQG-RPGKRIVGTMQGGDSDDN--EDSEESEIDMEDD 377
+ + E +R K + AM++ G R R+ S D+ E +ES I +
Sbjct: 407 EKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
Query: 378 DDED 381
E+
Sbjct: 467 GGEE 470
Score = 31.2 bits (69), Expect = 1.8
Identities = 37/146 (25%), Positives = 73/146 (50%), Gaps = 20/146 (13%)
Query: 197 QKTKDLLNNVASDEANLEAKIE-KRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQ 255
+KT LL+ + + + E K E +R+ E+ER R+R E + + EEE +K+
Sbjct: 195 KKTTPLLSFLKNKQRMREEKREERRRREIERKRQREE----------ERRKWKEEEKRKR 244
Query: 256 YDTYLEKFQNLTYLEQ--QLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDD 313
D +EK + + + + +L+D +++ + E + L + +E+ K+L K +D+
Sbjct: 245 KD--IEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDK---REKAKKLDKENLSDE 299
Query: 314 --SDIDIQEDDESDSELEERRLPKPQ 337
S SDSEL++ + +P+
Sbjct: 300 RASGQSCTLPKRSDSELKDEKPKRPE 325
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 46.6 bits (109), Expect = 4e-05
Identities = 61/282 (21%), Positives = 119/282 (42%), Gaps = 24/282 (8%)
Query: 138 KAARQLASEITSKGASLYDLLGMEVELREMRTEAIA-RPLEINETEKVMRIAIKEILTQV 196
K R ++ T YDL + L ++A++ + ++ +T+ I K ++ +
Sbjct: 55 KRGRPISHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKK 114
Query: 197 QKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEE----L 252
++TK + + ++ +L+ I +K++ K +++ S + + +K ++E +
Sbjct: 115 KETKKANHKGSENKTDLDNSIGIKKMKTSCKFK-IDSNISPKKDSKEFTQKNKKEKKNIV 173
Query: 253 QKQYDTYLEKFQN-LTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSN 311
Q D+ LE+ Q L ++ R+E + ++ + + G
Sbjct: 174 QHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEM 233
Query: 312 DDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESE 371
D D ++ED ES SE+ ++ E+ GR GD D +ED EE +
Sbjct: 234 CDKDA-LEEDSESVSEIGSDE----ESENEITSVGRAS---------GDDDGSEDDEEED 279
Query: 372 IDMEDDDD---EDDDLEDESISLSPTKPNRRVRKSEPLDESD 410
D E+D+D EDDD D L+ K N + D +D
Sbjct: 280 EDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTAD 321
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 46.2 bits (108), Expect = 5e-05
Identities = 56/216 (25%), Positives = 103/216 (47%), Gaps = 25/216 (11%)
Query: 164 LREMRTEAIARPLEINETEKVMRI-AIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL 222
LR+ + + R + E K + A + +L + ++ K+LL + +++ +IE +
Sbjct: 194 LRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKS---IEIENLQT 250
Query: 223 ELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTY-LEQQLEDHHRM-- 279
L++ + L+S PC E+ EEE QK L++ ++LT L ++ E+ RM
Sbjct: 251 RLQQLDEENSELRSCTPCLKANIERLEEEKQK----LLDEIESLTLRLSEEQENKRRMGD 306
Query: 280 ----EQERFEEAKN-TLCLIQNKLKE-EEKRLLKSGSND----DSDIDIQE----DDESD 325
E+ +F+ K T LI++ K+ E +LLK + S + +QE ES+
Sbjct: 307 RLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESE 366
Query: 326 SELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDS 361
E E RRL + ++ + G+ I ++QG S
Sbjct: 367 LEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKS 402
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,863,345
Number of Sequences: 37866
Number of extensions: 714213
Number of successful extensions: 11806
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 333
Number of HSP's successfully gapped in prelim test: 936
Number of HSP's that attempted gapping in prelim test: 5863
Number of HSP's gapped (non-prelim): 4063
length of query: 413
length of database: 18,247,518
effective HSP length: 105
effective length of query: 308
effective length of database: 14,271,588
effective search space: 4395649104
effective search space used: 4395649104
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.