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Search of human proteins with 51972284
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo
sapiens]
(114 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens] 228 8e-61
gi|56090539 dysferlin-interacting protein 1 [Homo sapiens] 72 7e-14
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 64 3e-11
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 64 3e-11
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 62 1e-10
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 62 1e-10
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 61 2e-10
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 55 9e-09
gi|17864094 feminization 1 homolog a [Homo sapiens] 55 2e-08
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 54 3e-08
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 54 3e-08
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 53 5e-08
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 53 5e-08
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 53 5e-08
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 53 6e-08
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 53 6e-08
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 53 6e-08
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 53 6e-08
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 53 6e-08
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 52 8e-08
gi|239754056 PREDICTED: ankyrin repeat and death domain containi... 52 1e-07
gi|239748583 PREDICTED: ankyrin repeat and death domain containi... 52 1e-07
gi|239742602 PREDICTED: ankyrin repeat and death domain containi... 52 1e-07
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1... 52 1e-07
gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens] 52 1e-07
gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens] 52 1e-07
gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens] 52 1e-07
gi|38683799 ankyrin repeat domain 13 [Homo sapiens] 52 1e-07
gi|24233530 ankyrin repeat domain 44 [Homo sapiens] 50 3e-07
gi|103471993 huntingtin interacting protein 14 [Homo sapiens] 50 3e-07
>gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens]
Length = 114
Score = 228 bits (581), Expect = 8e-61
Identities = 114/114 (100%), Positives = 114/114 (100%)
Query: 1 MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVI 60
MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVI
Sbjct: 1 MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVI 60
Query: 61 DGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAASGR 114
DGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAASGR
Sbjct: 61 DGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAASGR 114
>gi|56090539 dysferlin-interacting protein 1 [Homo sapiens]
Length = 154
Score = 72.4 bits (176), Expect = 7e-14
Identities = 35/89 (39%), Positives = 57/89 (64%), Gaps = 3/89 (3%)
Query: 17 IFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
+F + +R+G+ +++ ++ + ++ + P G ALH++V+ GNLE VKLLVK+GAD
Sbjct: 33 LFLDHIRQGDLEQVGRFIRTR---KVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGAD 89
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLIT 105
I + GW+ LHIA G+ DI YLI+
Sbjct: 90 IHQRDEAGWTPLHIACSDGYPDIARYLIS 118
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 63.5 bits (153), Expect = 3e-11
Identities = 35/96 (36%), Positives = 54/96 (56%), Gaps = 4/96 (4%)
Query: 17 IFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
+F A G+T E+ LL + +N +G TALHQ+ ID N+++VK LV+ GA+
Sbjct: 43 VFLAACSSGDTDEVLKLLHRGAD----INYANVDGLTALHQACIDDNVDMVKFLVENGAN 98
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
I + +GW LH AA G+ DI +LI + + +
Sbjct: 99 INQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGA 134
Score = 48.1 bits (113), Expect = 1e-06
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 20 EAVRKGNTQ-ELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIR 78
EA RK + L+ Q + + N G TALH + G E++KLL++ G D+
Sbjct: 167 EAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVN 226
Query: 79 LANRDGWSALHIAAFGGHQDIVLYLI 104
+ + DGW+ LH AA G ++ L+
Sbjct: 227 IKDYDGWTPLHAAAHWGKEEACRILV 252
Score = 34.3 bits (77), Expect = 0.022
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A KG T+ L+ L+Q ++VN +G T LH + G E ++LV D+ +
Sbjct: 206 AAAKGYTEVLKLLIQ----AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMV 261
Query: 81 NRDGWSALHIAAFGGHQDIVLYL 103
N+ G +A +A +DI+ YL
Sbjct: 262 NKVGQTAFDVA----DEDILGYL 280
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 63.5 bits (153), Expect = 3e-11
Identities = 35/96 (36%), Positives = 54/96 (56%), Gaps = 4/96 (4%)
Query: 17 IFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
+F A G+T E+ LL + +N +G TALHQ+ ID N+++VK LV+ GA+
Sbjct: 43 VFLAACSSGDTDEVLKLLHRGAD----INYANVDGLTALHQACIDDNVDMVKFLVENGAN 98
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
I + +GW LH AA G+ DI +LI + + +
Sbjct: 99 INQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGA 134
Score = 48.1 bits (113), Expect = 1e-06
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 20 EAVRKGNTQ-ELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIR 78
EA RK + L+ Q + + N G TALH + G E++KLL++ G D+
Sbjct: 167 EAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVN 226
Query: 79 LANRDGWSALHIAAFGGHQDIVLYLI 104
+ + DGW+ LH AA G ++ L+
Sbjct: 227 IKDYDGWTPLHAAAHWGKEEACRILV 252
Score = 34.3 bits (77), Expect = 0.022
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A KG T+ L+ L+Q ++VN +G T LH + G E ++LV D+ +
Sbjct: 206 AAAKGYTEVLKLLIQ----AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMV 261
Query: 81 NRDGWSALHIAAFGGHQDIVLYL 103
N+ G +A +A +DI+ YL
Sbjct: 262 NKVGQTAFDVA----DEDILGYL 280
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 62.0 bits (149), Expect = 1e-10
Identities = 33/88 (37%), Positives = 52/88 (59%), Gaps = 4/88 (4%)
Query: 17 IFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
+F A G+T E++ LL + +N+ +G TALHQ+ ID NL++VK LV+ A+
Sbjct: 61 VFLAACSSGDTDEVRKLLARGAD----INTVNVDGLTALHQACIDENLDMVKFLVENRAN 116
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLI 104
+ + +GW+ LH AA G+ +I Y I
Sbjct: 117 VNQQDNEGWTPLHAAASCGYLNIAEYFI 144
Score = 42.4 bits (98), Expect = 8e-05
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 15 QRIFQEAVRKGNTQE-LQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKF 73
Q I E RK Q+ LQ Q + + + G TALH + G E+++LL++
Sbjct: 180 QGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 74 GADIRLANRDGWSALHIAAFGG 95
G ++ + + DGW+ LH AA G
Sbjct: 240 GYELNVQDYDGWTPLHAAAHWG 261
Score = 25.8 bits (55), Expect = 7.8
Identities = 13/29 (44%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Query: 76 DIRLANRDGWSALHIAAFGGHQDIVLYLI 104
D+R A R G +ALH+AA G+ +++ LI
Sbjct: 210 DVRQA-RSGATALHVAAAKGYSEVLRLLI 237
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 62.0 bits (149), Expect = 1e-10
Identities = 33/88 (37%), Positives = 52/88 (59%), Gaps = 4/88 (4%)
Query: 17 IFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
+F A G+T E++ LL + +N+ +G TALHQ+ ID NL++VK LV+ A+
Sbjct: 61 VFLAACSSGDTDEVRKLLARGAD----INTVNVDGLTALHQACIDENLDMVKFLVENRAN 116
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLI 104
+ + +GW+ LH AA G+ +I Y I
Sbjct: 117 VNQQDNEGWTPLHAAASCGYLNIAEYFI 144
Score = 42.4 bits (98), Expect = 8e-05
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 15 QRIFQEAVRKGNTQE-LQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKF 73
Q I E RK Q+ LQ Q + + + G TALH + G E+++LL++
Sbjct: 180 QGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 74 GADIRLANRDGWSALHIAAFGG 95
G ++ + + DGW+ LH AA G
Sbjct: 240 GYELNVQDYDGWTPLHAAAHWG 261
Score = 25.8 bits (55), Expect = 7.8
Identities = 13/29 (44%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Query: 76 DIRLANRDGWSALHIAAFGGHQDIVLYLI 104
D+R A R G +ALH+AA G+ +++ LI
Sbjct: 210 DVRQA-RSGATALHVAAAKGYSEVLRLLI 237
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 60.8 bits (146), Expect = 2e-10
Identities = 28/62 (45%), Positives = 44/62 (70%)
Query: 44 VNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYL 103
++S +G +ALHQ+ ID NLE+V+ LV+ GA + A+ +GW+ LH+AA G+ DI YL
Sbjct: 94 LDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYL 153
Query: 104 IT 105
++
Sbjct: 154 LS 155
Score = 45.1 bits (105), Expect = 1e-05
Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 7/74 (9%)
Query: 31 QSLLQNMTNCEFNVNSFGPE------GQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
+ LL + T C N + PE G +ALH + G +E+++LL++ G D L + DG
Sbjct: 202 EELLLHDTRCWLNGGAM-PEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDG 260
Query: 85 WSALHIAAFGGHQD 98
W+ LH AA G +D
Sbjct: 261 WTPLHAAAHWGVED 274
Score = 33.5 bits (75), Expect = 0.037
Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 7/95 (7%)
Query: 4 AELSTCSAPQTQRIFQEAVRKGNTQELQSLL-QNMTNCEF------NVNSFGPEGQTALH 56
AEL + P + + G + Q+ + +N+ F VN EG T LH
Sbjct: 80 AELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLH 139
Query: 57 QSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
+ G L++ + L+ GA+I N DG L +A
Sbjct: 140 VAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLA 174
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 55.5 bits (132), Expect = 9e-09
Identities = 31/84 (36%), Positives = 48/84 (57%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+G+T+ + L+ C N+N +G TAL + G+ E+V L+ G + A
Sbjct: 585 AARQGHTKVVNCLI----GCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCA 640
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ D +AL AA+GGH+DIVL L+
Sbjct: 641 DADSRTALRAAAWGGHEDIVLNLL 664
Score = 51.2 bits (121), Expect = 2e-07
Identities = 26/62 (41%), Positives = 40/62 (64%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
NV + EG+TALH S G++E+V++L+ + AD+ A+ + SAL AA+ GH +V
Sbjct: 971 NVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 1030
Query: 103 LI 104
LI
Sbjct: 1031 LI 1032
Score = 45.8 bits (107), Expect = 7e-06
Identities = 25/61 (40%), Positives = 36/61 (59%)
Query: 44 VNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYL 103
V+S EG+T L + GN+E+V+ L+ G D + GW+ LH+AAF GH+ I L
Sbjct: 807 VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 866
Query: 104 I 104
I
Sbjct: 867 I 867
Score = 45.1 bits (105), Expect = 1e-05
Identities = 21/54 (38%), Positives = 34/54 (62%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T L + G+ ++V L+ GA+I ++DGW+AL AA+GGH ++V L+
Sbjct: 578 GHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALL 631
Score = 45.1 bits (105), Expect = 1e-05
Identities = 29/94 (30%), Positives = 54/94 (57%), Gaps = 7/94 (7%)
Query: 19 QEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIR 78
Q A +G+ + +Q L+++ + N +G TAL + +G++++V++L++ GAD
Sbjct: 1017 QSAAWQGHVKVVQLLIEHGAVVDHTCN----QGATALCIAAQEGHIDVVQVLLEHGADPN 1072
Query: 79 LANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
A++ G +A+ +AA GH I+ L KY AS
Sbjct: 1073 HADQFGRTAMRVAAKNGHSQIIKLL---EKYGAS 1103
Score = 43.5 bits (101), Expect = 4e-05
Identities = 29/92 (31%), Positives = 51/92 (55%), Gaps = 6/92 (6%)
Query: 13 QTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVK 72
+T I ++A+ + ++ +++LL N + VN G+T L + G+L++V LLV
Sbjct: 513 RTSCIVRQALEREDS--IRTLLDNGAS----VNQCDSNGRTLLANAAYSGSLDVVNLLVS 566
Query: 73 FGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
GAD+ + + G + L +AA GH +V LI
Sbjct: 567 RGADLEIEDAHGHTPLTLAARQGHTKVVNCLI 598
Score = 43.1 bits (100), Expect = 5e-05
Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+ +Q LL+N +N ++ G +G+ AL + ++G+ ++V+LL GAD+
Sbjct: 887 ASQEGHYDCVQILLENKSN----IDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCK 942
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ DG L+I A + Y +
Sbjct: 943 DADGRPTLYILALENQLTMAEYFL 966
Score = 40.4 bits (93), Expect = 3e-04
Identities = 24/80 (30%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
G+T+ + +LL V+ + +TAL + G+ ++V L++ GA++ A+ +G
Sbjct: 622 GHTEVVSALLY----AGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEG 677
Query: 85 WSALHIAAFGGHQDIVLYLI 104
+AL AA+ GH++IV +L+
Sbjct: 678 RTALIAAAYMGHREIVEHLL 697
Score = 39.7 bits (91), Expect = 5e-04
Identities = 22/79 (27%), Positives = 45/79 (56%), Gaps = 5/79 (6%)
Query: 31 QSLLQNMTNCEFNVNSFGPEGQTALHQSVI-----DGNLELVKLLVKFGADIRLANRDGW 85
+ +++++ + VN +G+TAL + + G+ +V LL+ GA++ ++DG
Sbjct: 690 REIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGM 749
Query: 86 SALHIAAFGGHQDIVLYLI 104
+ L +AA+ GH D+V L+
Sbjct: 750 TPLLVAAYEGHVDVVDLLL 768
Score = 39.3 bits (90), Expect = 7e-04
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
Query: 9 CSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVK 68
C+ ++ + A G+ + +LLQ+ VN EG+TAL + G+ E+V+
Sbjct: 639 CADADSRTALRAAAWGGHEDIVLNLLQHGAE----VNKADNEGRTALIAAAYMGHREIVE 694
Query: 69 LLVKFGADIRLANRDGWSALHIAAF-----GGHQDIVLYLITK 106
L+ GA++ + DG +AL +AA GH +V LI +
Sbjct: 695 HLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDR 737
Score = 38.9 bits (89), Expect = 9e-04
Identities = 22/62 (35%), Positives = 38/62 (61%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
+VN+ E ++AL + G++++V+LL++ GA + G +AL IAA GH D+V
Sbjct: 1004 DVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQV 1063
Query: 103 LI 104
L+
Sbjct: 1064 LL 1065
Score = 34.3 bits (77), Expect = 0.022
Identities = 18/55 (32%), Positives = 33/55 (60%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
+G T L + +G++++V LL++ GAD+ + +G + L AA GH +V L+
Sbjct: 747 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLL 801
Score = 33.1 bits (74), Expect = 0.049
Identities = 18/61 (29%), Positives = 34/61 (55%)
Query: 45 NSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
N +G+ + +G+ + V++L++ ++I DG +AL +AA GH+DIV L
Sbjct: 874 NEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLF 933
Query: 105 T 105
+
Sbjct: 934 S 934
Score = 32.0 bits (71), Expect = 0.11
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +GN + +++LL + N G T LH + +G+ + + L++ GA
Sbjct: 821 ASAQGNVEVVRTLLDR----GLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEI 876
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ DG +A+ GH D V L+
Sbjct: 877 DNDGRIPFILASQEGHYDCVQILL 900
Score = 28.1 bits (61), Expect = 1.6
Identities = 20/86 (23%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +G+ + LL+ + + N+ G+T L + G+ +V L+ +GA +
Sbjct: 755 AAYEGHVDVVDLLLEGGADVDHTDNN----GRTPLLAAASMGHASVVNTLLFWGAAVDSI 810
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
+ +G + L IA+ G+ ++V L+ +
Sbjct: 811 DSEGRTVLSIASAQGNVEVVRTLLDR 836
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 31 QSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHI 90
Q +LQ + +VNS + Q++ + ++ L+ GA + + +G + L
Sbjct: 494 QEVLQLLVKAGAHVNSEDDRTSCIVRQAL--EREDSIRTLLDNGASVNQCDSNGRTLLAN 551
Query: 91 AAFGGHQDIVLYLITK 106
AA+ G D+V L+++
Sbjct: 552 AAYSGSLDVVNLLVSR 567
>gi|17864094 feminization 1 homolog a [Homo sapiens]
Length = 617
Score = 54.7 bits (130), Expect = 2e-08
Identities = 27/74 (36%), Positives = 46/74 (62%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
++Q++ N +VN+ T L + DG+LE+VK LV+ AD+ ++NR G + L I+
Sbjct: 98 VVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISC 157
Query: 93 FGGHQDIVLYLITK 106
+ GH++I YL+ K
Sbjct: 158 YKGHKEIAQYLLEK 171
Score = 37.0 bits (84), Expect = 0.003
Identities = 17/42 (40%), Positives = 27/42 (64%)
Query: 63 NLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
+L++ +L++ GAD+ + + D S LHIAA H DI+ LI
Sbjct: 507 SLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLI 548
Score = 36.2 bits (82), Expect = 0.006
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 9/93 (9%)
Query: 24 KGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRD 83
KG+ + Q LL+ + VN +G TALH G+L+++K+L+ + A + +D
Sbjct: 159 KGHKEIAQYLLEKGAD----VNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKM---EKD 211
Query: 84 GW--SALHIAAFGGHQDIVLYLITKAKYAASGR 114
G+ + L A+ GH +IV +L A+ + + R
Sbjct: 212 GYGMTPLLSASVTGHTNIVDFLTHHAQTSKTER 244
Score = 34.3 bits (77), Expect = 0.022
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLIT-KAK 108
EG L + G+L++V+ L+ GA + + L A F GH +IV YL+ KA
Sbjct: 82 EGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKAD 141
Query: 109 YAASGR 114
S R
Sbjct: 142 LEVSNR 147
Score = 32.7 bits (73), Expect = 0.064
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T L S G+ E+ + L++ GAD+ + G +ALH A G DI+ L+
Sbjct: 149 GHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLL 202
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 53.5 bits (127), Expect = 3e-08
Identities = 24/55 (43%), Positives = 36/55 (65%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
EG TALH +V G+ E+VK LV+FG ++ A+ DGW+ LH AA + + +L+
Sbjct: 964 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLV 1018
Score = 34.7 bits (78), Expect = 0.017
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 55 LHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
L S ++G +LV+ ++ D L N +G +ALH A GH +IV +L+
Sbjct: 936 LLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLV 985
Score = 30.4 bits (67), Expect = 0.32
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 5 ELSTCSAPQTQRI--FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDG 62
E+ S P + I AV G+T+ ++ L+Q NVN+ +G T LH +
Sbjct: 954 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ----FGVNVNAADSDGWTPLHCAASCN 1009
Query: 63 NLELVKLLVKFGADI 77
N+++ K LV+ GA +
Sbjct: 1010 NVQVCKFLVESGAAV 1024
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 53.5 bits (127), Expect = 3e-08
Identities = 24/55 (43%), Positives = 36/55 (65%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
EG TALH +V G+ E+VK LV+FG ++ A+ DGW+ LH AA + + +L+
Sbjct: 835 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLV 889
Score = 34.7 bits (78), Expect = 0.017
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 55 LHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
L S ++G +LV+ ++ D L N +G +ALH A GH +IV +L+
Sbjct: 807 LLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLV 856
Score = 30.4 bits (67), Expect = 0.32
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 5 ELSTCSAPQTQRI--FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDG 62
E+ S P + I AV G+T+ ++ L+Q NVN+ +G T LH +
Sbjct: 825 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ----FGVNVNAADSDGWTPLHCAASCN 880
Query: 63 NLELVKLLVKFGADI 77
N+++ K LV+ GA +
Sbjct: 881 NVQVCKFLVESGAAV 895
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 53.1 bits (126), Expect = 5e-08
Identities = 28/72 (38%), Positives = 47/72 (65%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
L+Q + +V+S +G TALH + + G E+VK+LVK GA+I +++G++ L++AA
Sbjct: 58 LVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAA 117
Query: 93 FGGHQDIVLYLI 104
H D+V YL+
Sbjct: 118 QENHIDVVKYLL 129
Score = 48.5 bits (114), Expect = 1e-06
Identities = 24/62 (38%), Positives = 38/62 (61%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N N+ G T LH + +++++LLVK+GA I+ G + +H+AAF GH +IVL
Sbjct: 369 NPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLL 428
Query: 103 LI 104
L+
Sbjct: 429 LL 430
Score = 47.8 bits (112), Expect = 2e-06
Identities = 32/102 (31%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
Query: 11 APQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLL 70
A + Q A R G T+ +Q LLQ+M + + + G T LH S +G +++ +L
Sbjct: 473 AREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTN----GYTPLHISAREGQVDVASVL 528
Query: 71 VKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
++ GA LA + G++ LH+AA G D+ L+ + A S
Sbjct: 529 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADS 570
Score = 45.1 bits (105), Expect = 1e-05
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN ++ L+ ++N+ G ALH + +G++ LV+ L+ G+ +
Sbjct: 14 FLRAARAGNLDKVVEYLKG----GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSV 69
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
A + G +ALHIA+ G ++V L+
Sbjct: 70 DSATKKGNTALHIASLAGQAEVVKVLV 96
Score = 44.3 bits (103), Expect = 2e-05
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFN----VNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
A RK +T+ LLQN N + VN G T LH + GN+ + LL+ GA
Sbjct: 178 AARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAA 237
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ R+G + LH+A+ G+ ++V L+ +
Sbjct: 238 VDFTARNGITPLHVASKRGNTNMVKLLLDR 267
Score = 44.3 bits (103), Expect = 2e-05
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A GN LL +F + G T LH + GN +VKLL+ G I
Sbjct: 219 AAHYGNVNVATLLLNRGAAVDFTARN----GITPLHVASKRGNTNMVKLLLDRGGQIDAK 274
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
RDG + LH AA GH +V L+ +
Sbjct: 275 TRDGLTPLHCAARSGHDQVVELLLER 300
Score = 43.1 bits (100), Expect = 5e-05
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++GNT ++ LL + +G T LH + G+ ++V+LL++ GA +
Sbjct: 252 ASKRGNTNMVKLLLDRGGQIDAKTR----DGLTPLHCAARSGHDQVVELLLERGAPLLAR 307
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S LH+AA G H + V +L+
Sbjct: 308 TKNGLSPLHMAAQGDHVECVKHLL 331
Score = 40.0 bits (92), Expect = 4e-04
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +++ L+ +GA+ + + G + LH+A+ GH D+V L+ K
Sbjct: 608 GYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDK 663
Score = 39.3 bits (90), Expect = 7e-04
Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N+N+ G T L+ + + ++++VK L++ GA+ A DG++ L +A GH V
Sbjct: 101 NINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAI 160
Query: 103 LI---TKAK 108
L+ TK K
Sbjct: 161 LLENDTKGK 169
Score = 38.9 bits (89), Expect = 9e-04
Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 3/69 (4%)
Query: 24 KGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRD 83
K N ++ S L N E N+ + +G T LH + +G+ ++V LL+ GA+I ++ +
Sbjct: 617 KKNQMQIASTLLNY-GAETNIVT--KQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKS 673
Query: 84 GWSALHIAA 92
G ++LH+AA
Sbjct: 674 GLTSLHLAA 682
Score = 38.1 bits (87), Expect = 0.002
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G + ++ LL+N V++ E QT LH + G E+V+LL++ A A
Sbjct: 450 AARAGQVEVVRCLLRNGAL----VDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA 505
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+G++ LHI+A G D+ L+
Sbjct: 506 TTNGYTPLHISAREGQVDVASVLL 529
Score = 37.7 bits (86), Expect = 0.002
Identities = 20/62 (32%), Positives = 35/62 (56%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
++ + G T +H + G+L +V LL++ GA + N G +ALH+AA G ++V
Sbjct: 402 SIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC 461
Query: 103 LI 104
L+
Sbjct: 462 LL 463
Score = 37.4 bits (85), Expect = 0.003
Identities = 19/54 (35%), Positives = 32/54 (59%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T L + GN+++V L+K GA++ ++G++ LH AA GH I+ L+
Sbjct: 707 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 760
Score = 37.0 bits (84), Expect = 0.003
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G+TALH + G +E+V+ L++ GA + R+ + LHIA+ G +IV L+
Sbjct: 443 GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLL 496
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A GN + + LL+ N VN+ G T LHQ+ G+ ++ +L++ GA
Sbjct: 714 ACHYGNVKMVNFLLKQGAN----VNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNAT 769
Query: 81 NRDGWSALHIAAFGGHQDIV 100
+G +AL IA G+ +V
Sbjct: 770 TANGNTALAIAKRLGYISVV 789
Score = 33.5 bits (75), Expect = 0.037
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ Q ++ LL+ + G + LH + ++E VK L++ A +
Sbjct: 285 AARSGHDQVVELLLERGAPLLARTKN----GLSPLHMAAQGDHVECVKHLLQHKAPVDDV 340
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D +ALH+AA GH + L+ K
Sbjct: 341 TLDYLTALHVAAHCGHYRVTKLLLDK 366
Score = 33.5 bits (75), Expect = 0.037
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+T + LL N + S G T+LH + + + + +L K GAD
Sbjct: 648 ASQEGHTDMVTLLLDKGANIHMSTKS----GLTSLHLAAQEDKVNVADILTKHGADQDAH 703
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ G++ L +A G+ +V +L+
Sbjct: 704 TKLGYTPLIVACHYGNVKMVNFLL 727
Score = 32.7 bits (73), Expect = 0.064
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G+ + LLQ + S G G T LH + N ++ LL++ GA
Sbjct: 549 AAKYGSLDVAKLLLQRRAAAD----SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT 604
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G++ LHIAA I L+
Sbjct: 605 AKNGYTPLHIAAKKNQMQIASTLL 628
Score = 26.6 bits (57), Expect = 4.6
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 53 TALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
TALH + G+ + KLL+ A+ +G++ LHIA ++ L+ KY AS
Sbjct: 346 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV---KYGAS 402
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 53.1 bits (126), Expect = 5e-08
Identities = 28/72 (38%), Positives = 47/72 (65%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
L+Q + +V+S +G TALH + + G E+VK+LVK GA+I +++G++ L++AA
Sbjct: 79 LVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAA 138
Query: 93 FGGHQDIVLYLI 104
H D+V YL+
Sbjct: 139 QENHIDVVKYLL 150
Score = 48.5 bits (114), Expect = 1e-06
Identities = 24/62 (38%), Positives = 38/62 (61%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N N+ G T LH + +++++LLVK+GA I+ G + +H+AAF GH +IVL
Sbjct: 390 NPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLL 449
Query: 103 LI 104
L+
Sbjct: 450 LL 451
Score = 47.8 bits (112), Expect = 2e-06
Identities = 32/102 (31%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
Query: 11 APQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLL 70
A + Q A R G T+ +Q LLQ+M + + + G T LH S +G +++ +L
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTN----GYTPLHISAREGQVDVASVL 549
Query: 71 VKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
++ GA LA + G++ LH+AA G D+ L+ + A S
Sbjct: 550 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADS 591
Score = 45.1 bits (105), Expect = 1e-05
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN ++ L+ ++N+ G ALH + +G++ LV+ L+ G+ +
Sbjct: 35 FLRAARAGNLDKVVEYLKG----GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSV 90
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
A + G +ALHIA+ G ++V L+
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLV 117
Score = 44.3 bits (103), Expect = 2e-05
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFN----VNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
A RK +T+ LLQN N + VN G T LH + GN+ + LL+ GA
Sbjct: 199 AARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAA 258
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ R+G + LH+A+ G+ ++V L+ +
Sbjct: 259 VDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Score = 44.3 bits (103), Expect = 2e-05
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A GN LL +F + G T LH + GN +VKLL+ G I
Sbjct: 240 AAHYGNVNVATLLLNRGAAVDFTARN----GITPLHVASKRGNTNMVKLLLDRGGQIDAK 295
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
RDG + LH AA GH +V L+ +
Sbjct: 296 TRDGLTPLHCAARSGHDQVVELLLER 321
Score = 43.1 bits (100), Expect = 5e-05
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++GNT ++ LL + +G T LH + G+ ++V+LL++ GA +
Sbjct: 273 ASKRGNTNMVKLLLDRGGQIDAKTR----DGLTPLHCAARSGHDQVVELLLERGAPLLAR 328
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S LH+AA G H + V +L+
Sbjct: 329 TKNGLSPLHMAAQGDHVECVKHLL 352
Score = 40.0 bits (92), Expect = 4e-04
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +++ L+ +GA+ + + G + LH+A+ GH D+V L+ K
Sbjct: 629 GYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDK 684
Score = 39.3 bits (90), Expect = 7e-04
Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N+N+ G T L+ + + ++++VK L++ GA+ A DG++ L +A GH V
Sbjct: 122 NINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAI 181
Query: 103 LI---TKAK 108
L+ TK K
Sbjct: 182 LLENDTKGK 190
Score = 38.9 bits (89), Expect = 9e-04
Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 3/69 (4%)
Query: 24 KGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRD 83
K N ++ S L N E N+ + +G T LH + +G+ ++V LL+ GA+I ++ +
Sbjct: 638 KKNQMQIASTLLNY-GAETNIVT--KQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKS 694
Query: 84 GWSALHIAA 92
G ++LH+AA
Sbjct: 695 GLTSLHLAA 703
Score = 38.1 bits (87), Expect = 0.002
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G + ++ LL+N V++ E QT LH + G E+V+LL++ A A
Sbjct: 471 AARAGQVEVVRCLLRNGAL----VDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA 526
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+G++ LHI+A G D+ L+
Sbjct: 527 TTNGYTPLHISAREGQVDVASVLL 550
Score = 37.7 bits (86), Expect = 0.002
Identities = 20/62 (32%), Positives = 35/62 (56%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
++ + G T +H + G+L +V LL++ GA + N G +ALH+AA G ++V
Sbjct: 423 SIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC 482
Query: 103 LI 104
L+
Sbjct: 483 LL 484
Score = 37.4 bits (85), Expect = 0.003
Identities = 19/54 (35%), Positives = 32/54 (59%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T L + GN+++V L+K GA++ ++G++ LH AA GH I+ L+
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 781
Score = 37.0 bits (84), Expect = 0.003
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G+TALH + G +E+V+ L++ GA + R+ + LHIA+ G +IV L+
Sbjct: 464 GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLL 517
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A GN + + LL+ N VN+ G T LHQ+ G+ ++ +L++ GA
Sbjct: 735 ACHYGNVKMVNFLLKQGAN----VNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNAT 790
Query: 81 NRDGWSALHIAAFGGHQDIV 100
+G +AL IA G+ +V
Sbjct: 791 TANGNTALAIAKRLGYISVV 810
Score = 33.5 bits (75), Expect = 0.037
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ Q ++ LL+ + G + LH + ++E VK L++ A +
Sbjct: 306 AARSGHDQVVELLLERGAPLLARTKN----GLSPLHMAAQGDHVECVKHLLQHKAPVDDV 361
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D +ALH+AA GH + L+ K
Sbjct: 362 TLDYLTALHVAAHCGHYRVTKLLLDK 387
Score = 33.5 bits (75), Expect = 0.037
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+T + LL N + S G T+LH + + + + +L K GAD
Sbjct: 669 ASQEGHTDMVTLLLDKGANIHMSTKS----GLTSLHLAAQEDKVNVADILTKHGADQDAH 724
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ G++ L +A G+ +V +L+
Sbjct: 725 TKLGYTPLIVACHYGNVKMVNFLL 748
Score = 32.7 bits (73), Expect = 0.064
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G+ + LLQ + S G G T LH + N ++ LL++ GA
Sbjct: 570 AAKYGSLDVAKLLLQRRAAAD----SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT 625
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G++ LHIAA I L+
Sbjct: 626 AKNGYTPLHIAAKKNQMQIASTLL 649
Score = 26.6 bits (57), Expect = 4.6
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 53 TALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
TALH + G+ + KLL+ A+ +G++ LHIA ++ L+ KY AS
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV---KYGAS 423
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 53.1 bits (126), Expect = 5e-08
Identities = 28/72 (38%), Positives = 47/72 (65%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
L+Q + +V+S +G TALH + + G E+VK+LVK GA+I +++G++ L++AA
Sbjct: 79 LVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAA 138
Query: 93 FGGHQDIVLYLI 104
H D+V YL+
Sbjct: 139 QENHIDVVKYLL 150
Score = 48.5 bits (114), Expect = 1e-06
Identities = 24/62 (38%), Positives = 38/62 (61%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N N+ G T LH + +++++LLVK+GA I+ G + +H+AAF GH +IVL
Sbjct: 390 NPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLL 449
Query: 103 LI 104
L+
Sbjct: 450 LL 451
Score = 47.8 bits (112), Expect = 2e-06
Identities = 32/102 (31%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
Query: 11 APQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLL 70
A + Q A R G T+ +Q LLQ+M + + + G T LH S +G +++ +L
Sbjct: 494 AREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTN----GYTPLHISAREGQVDVASVL 549
Query: 71 VKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
++ GA LA + G++ LH+AA G D+ L+ + A S
Sbjct: 550 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADS 591
Score = 45.1 bits (105), Expect = 1e-05
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN ++ L+ ++N+ G ALH + +G++ LV+ L+ G+ +
Sbjct: 35 FLRAARAGNLDKVVEYLKG----GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSV 90
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
A + G +ALHIA+ G ++V L+
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLV 117
Score = 44.3 bits (103), Expect = 2e-05
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFN----VNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76
A RK +T+ LLQN N + VN G T LH + GN+ + LL+ GA
Sbjct: 199 AARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAA 258
Query: 77 IRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ R+G + LH+A+ G+ ++V L+ +
Sbjct: 259 VDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Score = 44.3 bits (103), Expect = 2e-05
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A GN LL +F + G T LH + GN +VKLL+ G I
Sbjct: 240 AAHYGNVNVATLLLNRGAAVDFTARN----GITPLHVASKRGNTNMVKLLLDRGGQIDAK 295
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
RDG + LH AA GH +V L+ +
Sbjct: 296 TRDGLTPLHCAARSGHDQVVELLLER 321
Score = 43.1 bits (100), Expect = 5e-05
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++GNT ++ LL + +G T LH + G+ ++V+LL++ GA +
Sbjct: 273 ASKRGNTNMVKLLLDRGGQIDAKTR----DGLTPLHCAARSGHDQVVELLLERGAPLLAR 328
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S LH+AA G H + V +L+
Sbjct: 329 TKNGLSPLHMAAQGDHVECVKHLL 352
Score = 40.0 bits (92), Expect = 4e-04
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +++ L+ +GA+ + + G + LH+A+ GH D+V L+ K
Sbjct: 629 GYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDK 684
Score = 39.3 bits (90), Expect = 7e-04
Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N+N+ G T L+ + + ++++VK L++ GA+ A DG++ L +A GH V
Sbjct: 122 NINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAI 181
Query: 103 LI---TKAK 108
L+ TK K
Sbjct: 182 LLENDTKGK 190
Score = 38.9 bits (89), Expect = 9e-04
Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 3/69 (4%)
Query: 24 KGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRD 83
K N ++ S L N E N+ + +G T LH + +G+ ++V LL+ GA+I ++ +
Sbjct: 638 KKNQMQIASTLLNY-GAETNIVT--KQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKS 694
Query: 84 GWSALHIAA 92
G ++LH+AA
Sbjct: 695 GLTSLHLAA 703
Score = 38.1 bits (87), Expect = 0.002
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G + ++ LL+N V++ E QT LH + G E+V+LL++ A A
Sbjct: 471 AARAGQVEVVRCLLRNGAL----VDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA 526
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+G++ LHI+A G D+ L+
Sbjct: 527 TTNGYTPLHISAREGQVDVASVLL 550
Score = 37.7 bits (86), Expect = 0.002
Identities = 20/62 (32%), Positives = 35/62 (56%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
++ + G T +H + G+L +V LL++ GA + N G +ALH+AA G ++V
Sbjct: 423 SIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC 482
Query: 103 LI 104
L+
Sbjct: 483 LL 484
Score = 37.4 bits (85), Expect = 0.003
Identities = 19/54 (35%), Positives = 32/54 (59%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T L + GN+++V L+K GA++ ++G++ LH AA GH I+ L+
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 781
Score = 37.0 bits (84), Expect = 0.003
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G+TALH + G +E+V+ L++ GA + R+ + LHIA+ G +IV L+
Sbjct: 464 GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLL 517
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A GN + + LL+ N VN+ G T LHQ+ G+ ++ +L++ GA
Sbjct: 735 ACHYGNVKMVNFLLKQGAN----VNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNAT 790
Query: 81 NRDGWSALHIAAFGGHQDIV 100
+G +AL IA G+ +V
Sbjct: 791 TANGNTALAIAKRLGYISVV 810
Score = 33.5 bits (75), Expect = 0.037
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ Q ++ LL+ + G + LH + ++E VK L++ A +
Sbjct: 306 AARSGHDQVVELLLERGAPLLARTKN----GLSPLHMAAQGDHVECVKHLLQHKAPVDDV 361
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D +ALH+AA GH + L+ K
Sbjct: 362 TLDYLTALHVAAHCGHYRVTKLLLDK 387
Score = 33.5 bits (75), Expect = 0.037
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+T + LL N + S G T+LH + + + + +L K GAD
Sbjct: 669 ASQEGHTDMVTLLLDKGANIHMSTKS----GLTSLHLAAQEDKVNVADILTKHGADQDAH 724
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ G++ L +A G+ +V +L+
Sbjct: 725 TKLGYTPLIVACHYGNVKMVNFLL 748
Score = 32.7 bits (73), Expect = 0.064
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G+ + LLQ + S G G T LH + N ++ LL++ GA
Sbjct: 570 AAKYGSLDVAKLLLQRRAAAD----SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT 625
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G++ LHIAA I L+
Sbjct: 626 AKNGYTPLHIAAKKNQMQIASTLL 649
Score = 26.6 bits (57), Expect = 4.6
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 53 TALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAAS 112
TALH + G+ + KLL+ A+ +G++ LHIA ++ L+ KY AS
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV---KYGAS 423
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 52.8 bits (125), Expect = 6e-08
Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T+ + LLQN VN+ + QT LH + G+ +VKLL++ A+ LA
Sbjct: 477 AARAGHTEVAKYLLQNKAK----VNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 532
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
G + LHIAA GH + VL L+ K
Sbjct: 533 TTAGHTPLHIAAREGHVETVLALLEK 558
Score = 52.4 bits (124), Expect = 8e-08
Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 10/102 (9%)
Query: 17 IFQEAVRKGNTQ-------ELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKL 69
I + +KGNT +++ + N NVN+ +G T L+ + + +LE+VK
Sbjct: 103 ILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 162
Query: 70 LVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI---TKAK 108
L++ GA+ +A DG++ L +A GH+++V +LI TK K
Sbjct: 163 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGK 204
Score = 45.4 bits (106), Expect = 9e-06
Identities = 24/54 (44%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T LH + GN++LVK L++ AD+ + G+S LH AA GH DIV L+
Sbjct: 734 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 787
Score = 42.0 bits (97), Expect = 1e-04
Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +K + + ++ LL+ + +++ G T LH + G+L +VK L++ GA ++
Sbjct: 411 ACKKNHVRVMELLLKTGAS----IDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 466
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI-TKAKYAASGR 114
N + LH+AA GH ++ YL+ KAK A +
Sbjct: 467 NVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 501
Score = 40.4 bits (93), Expect = 3e-04
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+GN ++ LL E + T LH + +G++ + ++L+ GA I+
Sbjct: 279 ASRRGNVIMVRLLLDRGAQIETKTK----DELTPLHCAARNGHVRISEILLDHGAPIQAK 334
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S +H+AA G H D V L+
Sbjct: 335 TKNGLSPIHMAAQGDHLDCVRLLL 358
Score = 40.4 bits (93), Expect = 3e-04
Identities = 22/62 (35%), Positives = 34/62 (54%)
Query: 45 NSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
NS G T LH + ++ +++LL+K GA I G + LH+A+F GH IV L+
Sbjct: 398 NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL 457
Query: 105 TK 106
+
Sbjct: 458 QR 459
Score = 40.0 bits (92), Expect = 4e-04
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++ + +SLLQ + N+ +G T LH + +G+ E+V LL+ A+ L
Sbjct: 642 AAKQNQVEVARSLLQYGGSA----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLG 697
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
N+ G + LH+ A GH + LI
Sbjct: 698 NKSGLTPLHLVAQEGHVPVADVLI 721
Score = 38.5 bits (88), Expect = 0.001
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN + L+N + +N+ G LH + +G++++V L+ +
Sbjct: 49 FLRAARSGNLDKALDHLRNGVD----INTCNQNGLNGLHLASKEGHVKMVVELLHKEIIL 104
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
+ G +ALHIAA G ++V L+
Sbjct: 105 ETTTKKGNTALHIAALAGQDEVVRELV 131
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G + + LL+ + + N+ G G T LH +V NL++VKLL+ G
Sbjct: 576 AAKYGKVRVAELLLER----DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 631
Query: 81 NRDGWSALHIAA 92
+G++ LHIAA
Sbjct: 632 AWNGYTPLHIAA 643
Score = 38.1 bits (87), Expect = 0.002
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+ + + LL N S G T LH +G++ + +L+K G +
Sbjct: 675 AAQEGHAEMVALLLSKQANGNLGNKS----GLTPLHLVAQEGHVPVADVLIKHGVMVDAT 730
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
R G++ LH+A+ G+ +V +L+
Sbjct: 731 TRMGYTPLHVASHYGNIKLVKFLL 754
Score = 37.7 bits (86), Expect = 0.002
Identities = 23/65 (35%), Positives = 34/65 (52%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
++ Q + N +VN G T LH + GN+ +V+LL+ GA I +D + LH A
Sbjct: 253 NVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCA 312
Query: 92 AFGGH 96
A GH
Sbjct: 313 ARNGH 317
Score = 36.6 bits (83), Expect = 0.004
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R +T+ LLQN + N + G T LH + NL + +LL+ GA +
Sbjct: 213 AARNDDTRTAAVLLQN----DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 268
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LHIA+ G+ +V L+ +
Sbjct: 269 PQNGITPLHIASRRGNVIMVRLLLDR 294
Score = 36.6 bits (83), Expect = 0.004
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +E+ + L+++G + G + LH+AA GH ++V L++K
Sbjct: 635 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 690
Score = 35.8 bits (81), Expect = 0.008
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 6/83 (7%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
GN + ++ LLQ+ + VN+ G + LHQ+ G+ ++V LL+K GA + DG
Sbjct: 745 GNIKLVKFLLQHQAD----VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDG 800
Query: 85 WSALHIAAFGGHQDI--VLYLIT 105
+ L IA G+ + VL ++T
Sbjct: 801 TTPLAIAKRLGYISVTDVLKVVT 823
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T ++ LL+N N + G T LH + +G++E V L++ A
Sbjct: 510 AARIGHTNMVKLLLENNANPNLATTA----GHTPLHIAAREGHVETVLALLEKEASQACM 565
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
+ G++ LH+AA G + L+ +
Sbjct: 566 TKKGFTPLHVAAKYGKVRVAELLLER 591
Score = 35.4 bits (80), Expect = 0.010
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+G+ + + +LL+ E + +G T LH + G + + +LL++ A A
Sbjct: 543 AAREGHVETVLALLEK----EASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAA 598
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LH+A + DIV L+ +
Sbjct: 599 GKNGLTPLHVAVHHNNLDIVKLLLPR 624
Score = 35.0 bits (79), Expect = 0.013
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ + + LL + + + G + +H + +L+ V+LL+++ A+I
Sbjct: 312 AARNGHVRISEILLDHGAPIQAKTKN----GLSPIHMAAQGDHLDCVRLLLQYDAEIDDI 367
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D + LH+AA GH + L+ K
Sbjct: 368 TLDHLTPLHVAAHCGHHRVAKVLLDK 393
Score = 33.9 bits (76), Expect = 0.029
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ T+ ++ GNL+ ++ G DI N++G + LH+A+ GH +V+ L+ K
Sbjct: 44 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 100
Score = 32.7 bits (73), Expect = 0.064
Identities = 19/72 (26%), Positives = 37/72 (51%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
+++N+ + N + +T LH + G+ E+ K L++ A + +D + LH AA
Sbjct: 452 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA 511
Query: 93 FGGHQDIVLYLI 104
GH ++V L+
Sbjct: 512 RIGHTNMVKLLL 523
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 52.8 bits (125), Expect = 6e-08
Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T+ + LLQN VN+ + QT LH + G+ +VKLL++ A+ LA
Sbjct: 444 AARAGHTEVAKYLLQNKAK----VNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
G + LHIAA GH + VL L+ K
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEK 525
Score = 52.4 bits (124), Expect = 8e-08
Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 10/102 (9%)
Query: 17 IFQEAVRKGNTQ-------ELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKL 69
I + +KGNT +++ + N NVN+ +G T L+ + + +LE+VK
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 129
Query: 70 LVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI---TKAK 108
L++ GA+ +A DG++ L +A GH+++V +LI TK K
Sbjct: 130 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGK 171
Score = 45.4 bits (106), Expect = 9e-06
Identities = 24/54 (44%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T LH + GN++LVK L++ AD+ + G+S LH AA GH DIV L+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 42.0 bits (97), Expect = 1e-04
Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +K + + ++ LL+ + +++ G T LH + G+L +VK L++ GA ++
Sbjct: 378 ACKKNHVRVMELLLKTGAS----IDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI-TKAKYAASGR 114
N + LH+AA GH ++ YL+ KAK A +
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 40.4 bits (93), Expect = 3e-04
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+GN ++ LL E + T LH + +G++ + ++L+ GA I+
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTK----DELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S +H+AA G H D V L+
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLL 325
Score = 40.4 bits (93), Expect = 3e-04
Identities = 22/62 (35%), Positives = 34/62 (54%)
Query: 45 NSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
NS G T LH + ++ +++LL+K GA I G + LH+A+F GH IV L+
Sbjct: 365 NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL 424
Query: 105 TK 106
+
Sbjct: 425 QR 426
Score = 40.0 bits (92), Expect = 4e-04
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++ + +SLLQ + N+ +G T LH + +G+ E+V LL+ A+ L
Sbjct: 609 AAKQNQVEVARSLLQYGGSA----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLG 664
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
N+ G + LH+ A GH + LI
Sbjct: 665 NKSGLTPLHLVAQEGHVPVADVLI 688
Score = 38.5 bits (88), Expect = 0.001
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN + L+N + +N+ G LH + +G++++V L+ +
Sbjct: 16 FLRAARSGNLDKALDHLRNGVD----INTCNQNGLNGLHLASKEGHVKMVVELLHKEIIL 71
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
+ G +ALHIAA G ++V L+
Sbjct: 72 ETTTKKGNTALHIAALAGQDEVVRELV 98
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G + + LL+ + + N+ G G T LH +V NL++VKLL+ G
Sbjct: 543 AAKYGKVRVAELLLER----DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 81 NRDGWSALHIAA 92
+G++ LHIAA
Sbjct: 599 AWNGYTPLHIAA 610
Score = 38.1 bits (87), Expect = 0.002
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+ + + LL N S G T LH +G++ + +L+K G +
Sbjct: 642 AAQEGHAEMVALLLSKQANGNLGNKS----GLTPLHLVAQEGHVPVADVLIKHGVMVDAT 697
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
R G++ LH+A+ G+ +V +L+
Sbjct: 698 TRMGYTPLHVASHYGNIKLVKFLL 721
Score = 37.7 bits (86), Expect = 0.002
Identities = 23/65 (35%), Positives = 34/65 (52%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
++ Q + N +VN G T LH + GN+ +V+LL+ GA I +D + LH A
Sbjct: 220 NVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCA 279
Query: 92 AFGGH 96
A GH
Sbjct: 280 ARNGH 284
Score = 36.6 bits (83), Expect = 0.004
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R +T+ LLQN + N + G T LH + NL + +LL+ GA +
Sbjct: 180 AARNDDTRTAAVLLQN----DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LHIA+ G+ +V L+ +
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 36.6 bits (83), Expect = 0.004
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +E+ + L+++G + G + LH+AA GH ++V L++K
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 35.8 bits (81), Expect = 0.008
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 6/83 (7%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
GN + ++ LLQ+ + VN+ G + LHQ+ G+ ++V LL+K GA + DG
Sbjct: 712 GNIKLVKFLLQHQAD----VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDG 767
Query: 85 WSALHIAAFGGHQDI--VLYLIT 105
+ L IA G+ + VL ++T
Sbjct: 768 TTPLAIAKRLGYISVTDVLKVVT 790
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T ++ LL+N N + G T LH + +G++E V L++ A
Sbjct: 477 AARIGHTNMVKLLLENNANPNLATTA----GHTPLHIAAREGHVETVLALLEKEASQACM 532
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
+ G++ LH+AA G + L+ +
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLER 558
Score = 35.4 bits (80), Expect = 0.010
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+G+ + + +LL+ E + +G T LH + G + + +LL++ A A
Sbjct: 510 AAREGHVETVLALLEK----EASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAA 565
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LH+A + DIV L+ +
Sbjct: 566 GKNGLTPLHVAVHHNNLDIVKLLLPR 591
Score = 35.0 bits (79), Expect = 0.013
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ + + LL + + + G + +H + +L+ V+LL+++ A+I
Sbjct: 279 AARNGHVRISEILLDHGAPIQAKTKN----GLSPIHMAAQGDHLDCVRLLLQYDAEIDDI 334
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D + LH+AA GH + L+ K
Sbjct: 335 TLDHLTPLHVAAHCGHHRVAKVLLDK 360
Score = 33.9 bits (76), Expect = 0.029
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ T+ ++ GNL+ ++ G DI N++G + LH+A+ GH +V+ L+ K
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Score = 32.7 bits (73), Expect = 0.064
Identities = 19/72 (26%), Positives = 37/72 (51%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
+++N+ + N + +T LH + G+ E+ K L++ A + +D + LH AA
Sbjct: 419 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA 478
Query: 93 FGGHQDIVLYLI 104
GH ++V L+
Sbjct: 479 RIGHTNMVKLLL 490
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 52.8 bits (125), Expect = 6e-08
Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T+ + LLQN VN+ + QT LH + G+ +VKLL++ A+ LA
Sbjct: 444 AARAGHTEVAKYLLQNKAK----VNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
G + LHIAA GH + VL L+ K
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEK 525
Score = 52.4 bits (124), Expect = 8e-08
Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 10/102 (9%)
Query: 17 IFQEAVRKGNTQ-------ELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKL 69
I + +KGNT +++ + N NVN+ +G T L+ + + +LE+VK
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 129
Query: 70 LVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI---TKAK 108
L++ GA+ +A DG++ L +A GH+++V +LI TK K
Sbjct: 130 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGK 171
Score = 45.4 bits (106), Expect = 9e-06
Identities = 24/54 (44%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T LH + GN++LVK L++ AD+ + G+S LH AA GH DIV L+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 42.0 bits (97), Expect = 1e-04
Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +K + + ++ LL+ + +++ G T LH + G+L +VK L++ GA ++
Sbjct: 378 ACKKNHVRVMELLLKTGAS----IDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI-TKAKYAASGR 114
N + LH+AA GH ++ YL+ KAK A +
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 40.4 bits (93), Expect = 3e-04
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+GN ++ LL E + T LH + +G++ + ++L+ GA I+
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTK----DELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S +H+AA G H D V L+
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLL 325
Score = 40.4 bits (93), Expect = 3e-04
Identities = 22/62 (35%), Positives = 34/62 (54%)
Query: 45 NSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
NS G T LH + ++ +++LL+K GA I G + LH+A+F GH IV L+
Sbjct: 365 NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL 424
Query: 105 TK 106
+
Sbjct: 425 QR 426
Score = 40.0 bits (92), Expect = 4e-04
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++ + +SLLQ + N+ +G T LH + +G+ E+V LL+ A+ L
Sbjct: 609 AAKQNQVEVARSLLQYGGSA----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLG 664
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
N+ G + LH+ A GH + LI
Sbjct: 665 NKSGLTPLHLVAQEGHVPVADVLI 688
Score = 38.5 bits (88), Expect = 0.001
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN + L+N + +N+ G LH + +G++++V L+ +
Sbjct: 16 FLRAARSGNLDKALDHLRNGVD----INTCNQNGLNGLHLASKEGHVKMVVELLHKEIIL 71
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
+ G +ALHIAA G ++V L+
Sbjct: 72 ETTTKKGNTALHIAALAGQDEVVRELV 98
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G + + LL+ + + N+ G G T LH +V NL++VKLL+ G
Sbjct: 543 AAKYGKVRVAELLLER----DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 81 NRDGWSALHIAA 92
+G++ LHIAA
Sbjct: 599 AWNGYTPLHIAA 610
Score = 38.1 bits (87), Expect = 0.002
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+ + + LL N S G T LH +G++ + +L+K G +
Sbjct: 642 AAQEGHAEMVALLLSKQANGNLGNKS----GLTPLHLVAQEGHVPVADVLIKHGVMVDAT 697
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
R G++ LH+A+ G+ +V +L+
Sbjct: 698 TRMGYTPLHVASHYGNIKLVKFLL 721
Score = 37.7 bits (86), Expect = 0.002
Identities = 23/65 (35%), Positives = 34/65 (52%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
++ Q + N +VN G T LH + GN+ +V+LL+ GA I +D + LH A
Sbjct: 220 NVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCA 279
Query: 92 AFGGH 96
A GH
Sbjct: 280 ARNGH 284
Score = 36.6 bits (83), Expect = 0.004
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R +T+ LLQN + N + G T LH + NL + +LL+ GA +
Sbjct: 180 AARNDDTRTAAVLLQN----DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LHIA+ G+ +V L+ +
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 36.6 bits (83), Expect = 0.004
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +E+ + L+++G + G + LH+AA GH ++V L++K
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 35.8 bits (81), Expect = 0.008
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 6/83 (7%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
GN + ++ LLQ+ + VN+ G + LHQ+ G+ ++V LL+K GA + DG
Sbjct: 712 GNIKLVKFLLQHQAD----VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDG 767
Query: 85 WSALHIAAFGGHQDI--VLYLIT 105
+ L IA G+ + VL ++T
Sbjct: 768 TTPLAIAKRLGYISVTDVLKVVT 790
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T ++ LL+N N + G T LH + +G++E V L++ A
Sbjct: 477 AARIGHTNMVKLLLENNANPNLATTA----GHTPLHIAAREGHVETVLALLEKEASQACM 532
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
+ G++ LH+AA G + L+ +
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLER 558
Score = 35.4 bits (80), Expect = 0.010
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+G+ + + +LL+ E + +G T LH + G + + +LL++ A A
Sbjct: 510 AAREGHVETVLALLEK----EASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAA 565
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LH+A + DIV L+ +
Sbjct: 566 GKNGLTPLHVAVHHNNLDIVKLLLPR 591
Score = 35.0 bits (79), Expect = 0.013
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ + + LL + + + G + +H + +L+ V+LL+++ A+I
Sbjct: 279 AARNGHVRISEILLDHGAPIQAKTKN----GLSPIHMAAQGDHLDCVRLLLQYDAEIDDI 334
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D + LH+AA GH + L+ K
Sbjct: 335 TLDHLTPLHVAAHCGHHRVAKVLLDK 360
Score = 33.9 bits (76), Expect = 0.029
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ T+ ++ GNL+ ++ G DI N++G + LH+A+ GH +V+ L+ K
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Score = 32.7 bits (73), Expect = 0.064
Identities = 19/72 (26%), Positives = 37/72 (51%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
+++N+ + N + +T LH + G+ E+ K L++ A + +D + LH AA
Sbjct: 419 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA 478
Query: 93 FGGHQDIVLYLI 104
GH ++V L+
Sbjct: 479 RIGHTNMVKLLL 490
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 52.8 bits (125), Expect = 6e-08
Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T+ + LLQN VN+ + QT LH + G+ +VKLL++ A+ LA
Sbjct: 444 AARAGHTEVAKYLLQNKAK----VNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
G + LHIAA GH + VL L+ K
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEK 525
Score = 52.4 bits (124), Expect = 8e-08
Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 10/102 (9%)
Query: 17 IFQEAVRKGNTQ-------ELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKL 69
I + +KGNT +++ + N NVN+ +G T L+ + + +LE+VK
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 129
Query: 70 LVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI---TKAK 108
L++ GA+ +A DG++ L +A GH+++V +LI TK K
Sbjct: 130 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGK 171
Score = 45.4 bits (106), Expect = 9e-06
Identities = 24/54 (44%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T LH + GN++LVK L++ AD+ + G+S LH AA GH DIV L+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 42.0 bits (97), Expect = 1e-04
Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +K + + ++ LL+ + +++ G T LH + G+L +VK L++ GA ++
Sbjct: 378 ACKKNHVRVMELLLKTGAS----IDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI-TKAKYAASGR 114
N + LH+AA GH ++ YL+ KAK A +
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 40.4 bits (93), Expect = 3e-04
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+GN ++ LL E + T LH + +G++ + ++L+ GA I+
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTK----DELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S +H+AA G H D V L+
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLL 325
Score = 40.4 bits (93), Expect = 3e-04
Identities = 22/62 (35%), Positives = 34/62 (54%)
Query: 45 NSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
NS G T LH + ++ +++LL+K GA I G + LH+A+F GH IV L+
Sbjct: 365 NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL 424
Query: 105 TK 106
+
Sbjct: 425 QR 426
Score = 40.0 bits (92), Expect = 4e-04
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++ + +SLLQ + N+ +G T LH + +G+ E+V LL+ A+ L
Sbjct: 609 AAKQNQVEVARSLLQYGGSA----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLG 664
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
N+ G + LH+ A GH + LI
Sbjct: 665 NKSGLTPLHLVAQEGHVPVADVLI 688
Score = 38.5 bits (88), Expect = 0.001
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN + L+N + +N+ G LH + +G++++V L+ +
Sbjct: 16 FLRAARSGNLDKALDHLRNGVD----INTCNQNGLNGLHLASKEGHVKMVVELLHKEIIL 71
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
+ G +ALHIAA G ++V L+
Sbjct: 72 ETTTKKGNTALHIAALAGQDEVVRELV 98
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G + + LL+ + + N+ G G T LH +V NL++VKLL+ G
Sbjct: 543 AAKYGKVRVAELLLER----DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 81 NRDGWSALHIAA 92
+G++ LHIAA
Sbjct: 599 AWNGYTPLHIAA 610
Score = 38.1 bits (87), Expect = 0.002
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+ + + LL N S G T LH +G++ + +L+K G +
Sbjct: 642 AAQEGHAEMVALLLSKQANGNLGNKS----GLTPLHLVAQEGHVPVADVLIKHGVMVDAT 697
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
R G++ LH+A+ G+ +V +L+
Sbjct: 698 TRMGYTPLHVASHYGNIKLVKFLL 721
Score = 37.7 bits (86), Expect = 0.002
Identities = 23/65 (35%), Positives = 34/65 (52%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
++ Q + N +VN G T LH + GN+ +V+LL+ GA I +D + LH A
Sbjct: 220 NVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCA 279
Query: 92 AFGGH 96
A GH
Sbjct: 280 ARNGH 284
Score = 36.6 bits (83), Expect = 0.004
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R +T+ LLQN + N + G T LH + NL + +LL+ GA +
Sbjct: 180 AARNDDTRTAAVLLQN----DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LHIA+ G+ +V L+ +
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 36.6 bits (83), Expect = 0.004
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +E+ + L+++G + G + LH+AA GH ++V L++K
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 35.8 bits (81), Expect = 0.008
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 6/83 (7%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
GN + ++ LLQ+ + VN+ G + LHQ+ G+ ++V LL+K GA + DG
Sbjct: 712 GNIKLVKFLLQHQAD----VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDG 767
Query: 85 WSALHIAAFGGHQDI--VLYLIT 105
+ L IA G+ + VL ++T
Sbjct: 768 TTPLAIAKRLGYISVTDVLKVVT 790
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T ++ LL+N N + G T LH + +G++E V L++ A
Sbjct: 477 AARIGHTNMVKLLLENNANPNLATTA----GHTPLHIAAREGHVETVLALLEKEASQACM 532
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
+ G++ LH+AA G + L+ +
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLER 558
Score = 35.4 bits (80), Expect = 0.010
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+G+ + + +LL+ E + +G T LH + G + + +LL++ A A
Sbjct: 510 AAREGHVETVLALLEK----EASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAA 565
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LH+A + DIV L+ +
Sbjct: 566 GKNGLTPLHVAVHHNNLDIVKLLLPR 591
Score = 35.0 bits (79), Expect = 0.013
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ + + LL + + + G + +H + +L+ V+LL+++ A+I
Sbjct: 279 AARNGHVRISEILLDHGAPIQAKTKN----GLSPIHMAAQGDHLDCVRLLLQYDAEIDDI 334
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D + LH+AA GH + L+ K
Sbjct: 335 TLDHLTPLHVAAHCGHHRVAKVLLDK 360
Score = 33.9 bits (76), Expect = 0.029
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ T+ ++ GNL+ ++ G DI N++G + LH+A+ GH +V+ L+ K
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Score = 32.7 bits (73), Expect = 0.064
Identities = 19/72 (26%), Positives = 37/72 (51%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
+++N+ + N + +T LH + G+ E+ K L++ A + +D + LH AA
Sbjct: 419 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA 478
Query: 93 FGGHQDIVLYLI 104
GH ++V L+
Sbjct: 479 RIGHTNMVKLLL 490
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 52.8 bits (125), Expect = 6e-08
Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T+ + LLQN VN+ + QT LH + G+ +VKLL++ A+ LA
Sbjct: 444 AARAGHTEVAKYLLQNKAK----VNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
G + LHIAA GH + VL L+ K
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEK 525
Score = 52.4 bits (124), Expect = 8e-08
Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 10/102 (9%)
Query: 17 IFQEAVRKGNTQ-------ELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKL 69
I + +KGNT +++ + N NVN+ +G T L+ + + +LE+VK
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 129
Query: 70 LVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI---TKAK 108
L++ GA+ +A DG++ L +A GH+++V +LI TK K
Sbjct: 130 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGK 171
Score = 45.4 bits (106), Expect = 9e-06
Identities = 24/54 (44%), Positives = 33/54 (61%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T LH + GN++LVK L++ AD+ + G+S LH AA GH DIV L+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 42.0 bits (97), Expect = 1e-04
Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +K + + ++ LL+ + +++ G T LH + G+L +VK L++ GA ++
Sbjct: 378 ACKKNHVRVMELLLKTGAS----IDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI-TKAKYAASGR 114
N + LH+AA GH ++ YL+ KAK A +
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 40.4 bits (93), Expect = 3e-04
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+GN ++ LL E + T LH + +G++ + ++L+ GA I+
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTK----DELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S +H+AA G H D V L+
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLL 325
Score = 40.4 bits (93), Expect = 3e-04
Identities = 22/62 (35%), Positives = 34/62 (54%)
Query: 45 NSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
NS G T LH + ++ +++LL+K GA I G + LH+A+F GH IV L+
Sbjct: 365 NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL 424
Query: 105 TK 106
+
Sbjct: 425 QR 426
Score = 40.0 bits (92), Expect = 4e-04
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++ + +SLLQ + N+ +G T LH + +G+ E+V LL+ A+ L
Sbjct: 609 AAKQNQVEVARSLLQYGGSA----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLG 664
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
N+ G + LH+ A GH + LI
Sbjct: 665 NKSGLTPLHLVAQEGHVPVADVLI 688
Score = 38.5 bits (88), Expect = 0.001
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
F A R GN + L+N + +N+ G LH + +G++++V L+ +
Sbjct: 16 FLRAARSGNLDKALDHLRNGVD----INTCNQNGLNGLHLASKEGHVKMVVELLHKEIIL 71
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLI 104
+ G +ALHIAA G ++V L+
Sbjct: 72 ETTTKKGNTALHIAALAGQDEVVRELV 98
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G + + LL+ + + N+ G G T LH +V NL++VKLL+ G
Sbjct: 543 AAKYGKVRVAELLLER----DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 81 NRDGWSALHIAA 92
+G++ LHIAA
Sbjct: 599 AWNGYTPLHIAA 610
Score = 38.1 bits (87), Expect = 0.002
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+ + + LL N S G T LH +G++ + +L+K G +
Sbjct: 642 AAQEGHAEMVALLLSKQANGNLGNKS----GLTPLHLVAQEGHVPVADVLIKHGVMVDAT 697
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
R G++ LH+A+ G+ +V +L+
Sbjct: 698 TRMGYTPLHVASHYGNIKLVKFLL 721
Score = 37.7 bits (86), Expect = 0.002
Identities = 23/65 (35%), Positives = 34/65 (52%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
++ Q + N +VN G T LH + GN+ +V+LL+ GA I +D + LH A
Sbjct: 220 NVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCA 279
Query: 92 AFGGH 96
A GH
Sbjct: 280 ARNGH 284
Score = 36.6 bits (83), Expect = 0.004
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R +T+ LLQN + N + G T LH + NL + +LL+ GA +
Sbjct: 180 AARNDDTRTAAVLLQN----DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LHIA+ G+ +V L+ +
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 36.6 bits (83), Expect = 0.004
Identities = 17/56 (30%), Positives = 31/56 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G T LH + +E+ + L+++G + G + LH+AA GH ++V L++K
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 35.8 bits (81), Expect = 0.008
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 6/83 (7%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
GN + ++ LLQ+ + VN+ G + LHQ+ G+ ++V LL+K GA + DG
Sbjct: 712 GNIKLVKFLLQHQAD----VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDG 767
Query: 85 WSALHIAAFGGHQDI--VLYLIT 105
+ L IA G+ + VL ++T
Sbjct: 768 TTPLAIAKRLGYISVTDVLKVVT 790
Score = 35.4 bits (80), Expect = 0.010
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+T ++ LL+N N + G T LH + +G++E V L++ A
Sbjct: 477 AARIGHTNMVKLLLENNANPNLATTA----GHTPLHIAAREGHVETVLALLEKEASQACM 532
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
+ G++ LH+AA G + L+ +
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLER 558
Score = 35.4 bits (80), Expect = 0.010
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R+G+ + + +LL+ E + +G T LH + G + + +LL++ A A
Sbjct: 510 AAREGHVETVLALLEK----EASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAA 565
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
++G + LH+A + DIV L+ +
Sbjct: 566 GKNGLTPLHVAVHHNNLDIVKLLLPR 591
Score = 35.0 bits (79), Expect = 0.013
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G+ + + LL + + + G + +H + +L+ V+LL+++ A+I
Sbjct: 279 AARNGHVRISEILLDHGAPIQAKTKN----GLSPIHMAAQGDHLDCVRLLLQYDAEIDDI 334
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
D + LH+AA GH + L+ K
Sbjct: 335 TLDHLTPLHVAAHCGHHRVAKVLLDK 360
Score = 33.9 bits (76), Expect = 0.029
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ T+ ++ GNL+ ++ G DI N++G + LH+A+ GH +V+ L+ K
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Score = 32.7 bits (73), Expect = 0.064
Identities = 19/72 (26%), Positives = 37/72 (51%)
Query: 33 LLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
+++N+ + N + +T LH + G+ E+ K L++ A + +D + LH AA
Sbjct: 419 IVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA 478
Query: 93 FGGHQDIVLYLI 104
GH ++V L+
Sbjct: 479 RIGHTNMVKLLL 490
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 52.4 bits (124), Expect = 8e-08
Identities = 28/84 (33%), Positives = 53/84 (63%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++G+ + + LLQ E NV++ +G TALH + + G E+VK+LV GA++
Sbjct: 81 ASKEGHVEVVSELLQR----EANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ 136
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+++G++ L++AA H ++V +L+
Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLL 160
Score = 45.1 bits (105), Expect = 1e-05
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A R G + ++ L+Q+ E + QT LH S G ++V+ L++ GA A
Sbjct: 473 AARSGQAEVVRYLVQDGAQVEAKAK----DDQTPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
G++ LH++A GH+D+ +L+
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLL 552
Score = 44.3 bits (103), Expect = 2e-05
Identities = 25/88 (28%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Query: 18 FQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADI 77
+ A R G+ ++ ++N + +N G ALH + +G++E+V L++ A++
Sbjct: 45 YLRAARAGHLEKALDYIKNGVD----INICNQNGLNALHLASKEGHVEVVSELLQREANV 100
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLIT 105
A + G +ALHIA+ G ++V L+T
Sbjct: 101 DAATKKGNTALHIASLAGQAEVVKVLVT 128
Score = 44.3 bits (103), Expect = 2e-05
Identities = 33/98 (33%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 21 AVRKGNTQ-ELQSL------LQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKF 73
A +KGNT + SL ++ + NVN+ G T L+ + + +LE+VK L+
Sbjct: 103 ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDN 162
Query: 74 GADIRLANRDGWSALHIAAFGGHQDIVLYLI---TKAK 108
GA LA DG++ L +A GH +V L+ TK K
Sbjct: 163 GASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGK 200
Score = 43.9 bits (102), Expect = 3e-05
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A GN LL +F + T LH + GN +VKLL+ GA I
Sbjct: 242 AAHYGNINVATLLLNRAAAVDFTARN----DITPLHVASKRGNANMVKLLLDRGAKIDAK 297
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITKA 107
RDG + LH A GH+ +V L+ +A
Sbjct: 298 TRDGLTPLHCGARSGHEQVVEMLLDRA 324
Score = 43.5 bits (101), Expect = 4e-05
Identities = 22/62 (35%), Positives = 36/62 (58%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N N+ G T LH + +++++LL+K GA I+ G + +H+AAF GH +IV
Sbjct: 392 NPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQ 451
Query: 103 LI 104
L+
Sbjct: 452 LM 453
Score = 43.5 bits (101), Expect = 4e-05
Identities = 23/60 (38%), Positives = 34/60 (56%)
Query: 45 NSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
N+ G+TALH + G E+V+ LV+ GA + +D + LHI+A G DIV L+
Sbjct: 460 NTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLL 519
Score = 40.4 bits (93), Expect = 3e-04
Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
+ R G +Q LLQ + N+ G T LH S +G+ ++ L+ GA + +
Sbjct: 506 SARLGKADIVQQLLQQGAS----PNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSIT 561
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITKA 107
+ G++ LH+AA G ++ L+ K+
Sbjct: 562 TKKGFTPLHVAAKYGKLEVANLLLQKS 588
Score = 40.0 bits (92), Expect = 4e-04
Identities = 18/54 (33%), Positives = 31/54 (57%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T LH + +++ L+++GAD R G +++H+AA GH D+V L+
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 684
Score = 39.7 bits (91), Expect = 5e-04
Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A RK +T+ LLQN N + S G T LH + GN+ + LL+ A +
Sbjct: 209 AARKDDTKAAALLLQNDNNADVESKS----GFTPLHIAAHYGNINVATLLLNRAAAVDFT 264
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK-AKYAASGR 114
R+ + LH+A+ G+ ++V L+ + AK A R
Sbjct: 265 ARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTR 299
Score = 39.7 bits (91), Expect = 5e-04
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A +K + ++ LL++ + + S G T +H + G++ +V L+ GA
Sbjct: 407 ACKKNRIKVMELLLKHGASIQAVTES----GLTPIHVAAFMGHVNIVSQLMHHGASPNTT 462
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
N G +ALH+AA G ++V YL+
Sbjct: 463 NVRGETALHMAARSGQAEVVRYLV 486
Score = 37.7 bits (86), Expect = 0.002
Identities = 18/54 (33%), Positives = 30/54 (55%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T LH GN+++V L++ A + ++G++ LH AA GH I+ L+
Sbjct: 730 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLL 783
Score = 37.4 bits (85), Expect = 0.003
Identities = 17/45 (37%), Positives = 29/45 (64%)
Query: 62 GNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G+LE +K G DI + N++G +ALH+A+ GH ++V L+ +
Sbjct: 52 GHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQR 96
Score = 37.0 bits (84), Expect = 0.003
Identities = 16/67 (23%), Positives = 39/67 (58%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
+ N+ +G ++H + +G++++V LL+ A++ L+N+ G + LH+AA ++
Sbjct: 656 DANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEV 715
Query: 103 LITKAKY 109
L+ + +
Sbjct: 716 LVNQGAH 722
Score = 35.4 bits (80), Expect = 0.010
Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A ++GN ++ LL + +G T LH G+ ++V++L+ A I
Sbjct: 275 ASKRGNANMVKLLLDRGAKIDAKTR----DGLTPLHCGARSGHEQVVEMLLDRAAPILSK 330
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G S LH+A G H + V L+
Sbjct: 331 TKNGLSPLHMATQGDHLNCVQLLL 354
Score = 35.4 bits (80), Expect = 0.010
Identities = 18/62 (29%), Positives = 32/62 (51%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
NVN G T LH + + + + ++LV GA + + G++ LH+ G+ IV +
Sbjct: 689 NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNF 748
Query: 103 LI 104
L+
Sbjct: 749 LL 750
Score = 35.0 bits (79), Expect = 0.013
Identities = 19/55 (34%), Positives = 30/55 (54%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
+G T LH + G LE+ LL++ A A + G + LH+AA +Q + L L+
Sbjct: 564 KGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLL 618
Score = 35.0 bits (79), Expect = 0.013
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A + G + LLQ + + + G G T LH + N ++ LL+ GA A
Sbjct: 572 AAKYGKLEVANLLLQKSASPD----AAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAA 627
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
++G++ LHIAA DI L+
Sbjct: 628 AKNGYTPLHIAAKKNQMDIATTLL 651
Score = 34.3 bits (77), Expect = 0.022
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 23 RKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANR 82
R G+ Q ++ LL + S G + LH + +L V+LL++ +
Sbjct: 310 RSGHEQVVEMLLDRAAP----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTN 365
Query: 83 DGWSALHIAAFGGHQDIVLYLITK 106
D +ALH+AA GH + L+ K
Sbjct: 366 DYLTALHVAAHCGHYKVAKVLLDK 389
Score = 31.6 bits (70), Expect = 0.14
Identities = 22/87 (25%), Positives = 44/87 (50%), Gaps = 8/87 (9%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A+++G+ Q + LL+N T G ALH + + + LL++ + +
Sbjct: 180 ALQQGHDQVVSLLLENDTK--------GKVRLPALHIAARKDDTKAAALLLQNDNNADVE 231
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITKA 107
++ G++ LHIAA G+ ++ L+ +A
Sbjct: 232 SKSGFTPLHIAAHYGNINVATLLLNRA 258
Score = 30.0 bits (66), Expect = 0.41
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
GN + + LLQ+ VN+ G T LHQ+ G+ ++ +L++ A +G
Sbjct: 741 GNIKIVNFLLQHSAK----VNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNG 796
Query: 85 WSALHIAAFGGHQDIV 100
+AL IA G+ +V
Sbjct: 797 NTALGIARRLGYISVV 812
>gi|239754056 PREDICTED: ankyrin repeat and death domain containing
1B [Homo sapiens]
Length = 524
Score = 52.0 bits (123), Expect = 1e-07
Identities = 27/54 (50%), Positives = 34/54 (62%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T +H + G+LE++ +LVK GAD R N+DG SALH A H IV YLI
Sbjct: 134 GLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYLI 187
Score = 48.5 bits (114), Expect = 1e-06
Identities = 26/90 (28%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 15 QRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFG 74
+R FQ A + N ++ L + + N+N +TALH +V +L V L+K
Sbjct: 69 ERSFQNAAKSNNLDLMEKLFEK----KVNINVVNNMNRTALHFAVGRNHLSAVDFLLKHK 124
Query: 75 ADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
A + +A++ G + +H+AA+ G +++L L+
Sbjct: 125 ARVDVADKHGLTVIHLAAWSGSLEVMLMLV 154
Score = 47.8 bits (112), Expect = 2e-06
Identities = 23/80 (28%), Positives = 47/80 (58%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
+++ ++ + + +++ + QT LH + GN+ELV+ L+K G D++ ++ G +AL +A
Sbjct: 360 TVVNSLLSAQHDIDILNQKQQTPLHVAADRGNVELVETLLKAGCDLKAVDKQGKTALAVA 419
Query: 92 AFGGHQDIVLYLITKAKYAA 111
+ H +V LI +Y A
Sbjct: 420 SRSNHSLVVGMLIKAERYYA 439
Score = 33.5 bits (75), Expect = 0.037
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G TALH + G+ V++L+ DI N S+L IA GH +V +L+++
Sbjct: 280 GNTALHLAAKHGHSPAVQVLLAQWQDINEMNELNISSLQIATRNGHASLVNFLLSE 335
Score = 31.2 bits (69), Expect = 0.18
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Query: 19 QEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIR 78
Q A R G+ + LL + V ++ LH VI+ ++ +V L+ DI
Sbjct: 318 QIATRNGHASLVNFLLSENVDLHQKVEP----KESPLHLVVINNHITVVNSLLSAQHDID 373
Query: 79 LANRDGWSALHIAAFGGHQDIVLYLI 104
+ N+ + LH+AA G+ ++V L+
Sbjct: 374 ILNQKQQTPLHVAADRGNVELVETLL 399
>gi|239748583 PREDICTED: ankyrin repeat and death domain containing
1B [Homo sapiens]
Length = 524
Score = 52.0 bits (123), Expect = 1e-07
Identities = 27/54 (50%), Positives = 34/54 (62%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T +H + G+LE++ +LVK GAD R N+DG SALH A H IV YLI
Sbjct: 134 GLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYLI 187
Score = 48.5 bits (114), Expect = 1e-06
Identities = 26/90 (28%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 15 QRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFG 74
+R FQ A + N ++ L + + N+N +TALH +V +L V L+K
Sbjct: 69 ERSFQNAAKSNNLDLMEKLFEK----KVNINVVNNMNRTALHFAVGRNHLSAVDFLLKHK 124
Query: 75 ADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
A + +A++ G + +H+AA+ G +++L L+
Sbjct: 125 ARVDVADKHGLTVIHLAAWSGSLEVMLMLV 154
Score = 47.8 bits (112), Expect = 2e-06
Identities = 23/80 (28%), Positives = 47/80 (58%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
+++ ++ + + +++ + QT LH + GN+ELV+ L+K G D++ ++ G +AL +A
Sbjct: 360 TVVNSLLSAQHDIDILNQKQQTPLHVAADRGNVELVETLLKAGCDLKAVDKQGKTALAVA 419
Query: 92 AFGGHQDIVLYLITKAKYAA 111
+ H +V LI +Y A
Sbjct: 420 SRSNHSLVVGMLIKAERYYA 439
Score = 33.5 bits (75), Expect = 0.037
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G TALH + G+ V++L+ DI N S+L IA GH +V +L+++
Sbjct: 280 GNTALHLAAKHGHSPAVQVLLAQWQDINEMNELNISSLQIATRNGHASLVNFLLSE 335
Score = 31.2 bits (69), Expect = 0.18
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Query: 19 QEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIR 78
Q A R G+ + LL + V ++ LH VI+ ++ +V L+ DI
Sbjct: 318 QIATRNGHASLVNFLLSENVDLHQKVEP----KESPLHLVVINNHITVVNSLLSAQHDID 373
Query: 79 LANRDGWSALHIAAFGGHQDIVLYLI 104
+ N+ + LH+AA G+ ++V L+
Sbjct: 374 ILNQKQQTPLHVAADRGNVELVETLL 399
>gi|239742602 PREDICTED: ankyrin repeat and death domain containing
1B [Homo sapiens]
Length = 607
Score = 52.0 bits (123), Expect = 1e-07
Identities = 27/54 (50%), Positives = 34/54 (62%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
G T +H + G+LE++ +LVK GAD R N+DG SALH A H IV YLI
Sbjct: 134 GLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYLI 187
Score = 48.5 bits (114), Expect = 1e-06
Identities = 26/90 (28%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 15 QRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFG 74
+R FQ A + N ++ L + + N+N +TALH +V +L V L+K
Sbjct: 69 ERSFQNAAKSNNLDLMEKLFEK----KVNINVVNNMNRTALHFAVGRNHLSAVDFLLKHK 124
Query: 75 ADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
A + +A++ G + +H+AA+ G +++L L+
Sbjct: 125 ARVDVADKHGLTVIHLAAWSGSLEVMLMLV 154
Score = 47.8 bits (112), Expect = 2e-06
Identities = 23/80 (28%), Positives = 47/80 (58%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
+++ ++ + + +++ + QT LH + GN+ELV+ L+K G D++ ++ G +AL +A
Sbjct: 360 TVVNSLLSAQHDIDILNQKQQTPLHVAADRGNVELVETLLKAGCDLKAVDKQGKTALAVA 419
Query: 92 AFGGHQDIVLYLITKAKYAA 111
+ H +V LI +Y A
Sbjct: 420 SRSNHSLVVGMLIKAERYYA 439
Score = 33.5 bits (75), Expect = 0.037
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G TALH + G+ V++L+ DI N S+L IA GH +V +L+++
Sbjct: 280 GNTALHLAAKHGHSPAVQVLLAQWQDINEMNELNISSLQIATRNGHASLVNFLLSE 335
Score = 31.2 bits (69), Expect = 0.18
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Query: 19 QEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIR 78
Q A R G+ + LL + V ++ LH VI+ ++ +V L+ DI
Sbjct: 318 QIATRNGHASLVNFLLSENVDLHQKVEP----KESPLHLVVINNHITVVNSLLSAQHDID 373
Query: 79 LANRDGWSALHIAAFGGHQDIVLYLI 104
+ N+ + LH+AA G+ ++V L+
Sbjct: 374 ILNQKQQTPLHVAADRGNVELVETLL 399
>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
[Homo sapiens]
Length = 567
Score = 52.0 bits (123), Expect = 1e-07
Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
Query: 20 EAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRL 79
EA + + +E++ L+N + + +G TALHQ ID E+VKLL+ GA++
Sbjct: 74 EASLRNDAEEVRYFLKNKVSPDL----CNEDGLTALHQCCIDNFEEIVKLLLSHGANVNA 129
Query: 80 ANRDGWSALHIAAFGGHQDIVLYLI 104
+ + W+ LH AA GH ++V L+
Sbjct: 130 KDNELWTPLHAAATCGHINLVKILV 154
Score = 42.4 bits (98), Expect = 8e-05
Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 6 LSTCSAPQ--TQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGN 63
+ TC A Q TQ E +R Q++ + + M +++ +G T LH + +G
Sbjct: 183 IETCMAYQGITQEKINE-MRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGY 241
Query: 64 LELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLIT 105
L +LL+ G + + + DGW LH AAF G + L++
Sbjct: 242 LRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVS 283
Score = 39.3 bits (90), Expect = 7e-04
Identities = 19/42 (45%), Positives = 27/42 (64%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
NVN+ E T LH + G++ LVK+LV++GAD+ N DG
Sbjct: 126 NVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDG 167
Score = 28.5 bits (62), Expect = 1.2
Identities = 16/56 (28%), Positives = 27/56 (48%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLIT 105
E AL ++ + + E V+ +K L N DG +ALH ++IV L++
Sbjct: 67 EASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLS 122
>gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
Length = 1873
Score = 51.6 bits (122), Expect = 1e-07
Identities = 25/61 (40%), Positives = 38/61 (62%)
Query: 44 VNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYL 103
+N G++ LH +V GNL LVK L++ GAD+ L + GW+ LH A+ G DI++ L
Sbjct: 1148 INKRNARGESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVEL 1207
Query: 104 I 104
+
Sbjct: 1208 L 1208
Score = 44.3 bits (103), Expect = 2e-05
Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
AVR+GN +++L+++ + N N+ G T LH++ +G+++++ L+K GA +
Sbjct: 1162 AVRRGNLPLVKALIESGADVNLNDNA----GWTPLHEASNEGSIDIIVELLKAGAKVNCE 1217
Query: 81 NRDGWSALHIAAFGGH 96
N DG LH A H
Sbjct: 1218 NIDGILPLHDAVANNH 1233
Score = 35.8 bits (81), Expect = 0.008
Identities = 20/62 (32%), Positives = 29/62 (46%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
NVN G TALH++ + G L+K GAD+ + + LH A GH +
Sbjct: 514 NVNQPSYAGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAEL 573
Query: 103 LI 104
L+
Sbjct: 574 LL 575
Score = 32.7 bits (73), Expect = 0.064
Identities = 13/45 (28%), Positives = 27/45 (60%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGG 95
G+ ++++ + + +LV +K G ++ + GW+ALH A+ GG
Sbjct: 489 GENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASVGG 533
Score = 30.8 bits (68), Expect = 0.24
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSAL 88
+VN G T LH +V++G+ ++ +LL+ GAD N DG AL
Sbjct: 547 DVNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCAL 592
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 27 TQELQSLLQNMTNCEFNVNSFGPEGQTALHQSV 59
T+ Q+LLQ NC + SF G + HQ++
Sbjct: 101 TERNQALLQTRKNCSMFIGSFRQSGLSLNHQNI 133
>gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
Length = 1873
Score = 51.6 bits (122), Expect = 1e-07
Identities = 25/61 (40%), Positives = 38/61 (62%)
Query: 44 VNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYL 103
+N G++ LH +V GNL LVK L++ GAD+ L + GW+ LH A+ G DI++ L
Sbjct: 1148 INKRNARGESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVEL 1207
Query: 104 I 104
+
Sbjct: 1208 L 1208
Score = 44.3 bits (103), Expect = 2e-05
Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
AVR+GN +++L+++ + N N+ G T LH++ +G+++++ L+K GA +
Sbjct: 1162 AVRRGNLPLVKALIESGADVNLNDNA----GWTPLHEASNEGSIDIIVELLKAGAKVNCE 1217
Query: 81 NRDGWSALHIAAFGGH 96
N DG LH A H
Sbjct: 1218 NIDGILPLHDAVANNH 1233
Score = 35.8 bits (81), Expect = 0.008
Identities = 20/62 (32%), Positives = 29/62 (46%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
NVN G TALH++ + G L+K GAD+ + + LH A GH +
Sbjct: 514 NVNQPSYAGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAEL 573
Query: 103 LI 104
L+
Sbjct: 574 LL 575
Score = 32.7 bits (73), Expect = 0.064
Identities = 13/45 (28%), Positives = 27/45 (60%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGG 95
G+ ++++ + + +LV +K G ++ + GW+ALH A+ GG
Sbjct: 489 GENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASVGG 533
Score = 30.8 bits (68), Expect = 0.24
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSAL 88
+VN G T LH +V++G+ ++ +LL+ GAD N DG AL
Sbjct: 547 DVNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCAL 592
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 27 TQELQSLLQNMTNCEFNVNSFGPEGQTALHQSV 59
T+ Q+LLQ NC + SF G + HQ++
Sbjct: 101 TERNQALLQTRKNCSMFIGSFRQSGLSLNHQNI 133
>gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
Length = 1873
Score = 51.6 bits (122), Expect = 1e-07
Identities = 25/61 (40%), Positives = 38/61 (62%)
Query: 44 VNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYL 103
+N G++ LH +V GNL LVK L++ GAD+ L + GW+ LH A+ G DI++ L
Sbjct: 1148 INKRNARGESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVEL 1207
Query: 104 I 104
+
Sbjct: 1208 L 1208
Score = 44.3 bits (103), Expect = 2e-05
Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
AVR+GN +++L+++ + N N+ G T LH++ +G+++++ L+K GA +
Sbjct: 1162 AVRRGNLPLVKALIESGADVNLNDNA----GWTPLHEASNEGSIDIIVELLKAGAKVNCE 1217
Query: 81 NRDGWSALHIAAFGGH 96
N DG LH A H
Sbjct: 1218 NIDGILPLHDAVANNH 1233
Score = 35.8 bits (81), Expect = 0.008
Identities = 20/62 (32%), Positives = 29/62 (46%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
NVN G TALH++ + G L+K GAD+ + + LH A GH +
Sbjct: 514 NVNQPSYAGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAEL 573
Query: 103 LI 104
L+
Sbjct: 574 LL 575
Score = 32.7 bits (73), Expect = 0.064
Identities = 13/45 (28%), Positives = 27/45 (60%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGG 95
G+ ++++ + + +LV +K G ++ + GW+ALH A+ GG
Sbjct: 489 GENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASVGG 533
Score = 30.8 bits (68), Expect = 0.24
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSAL 88
+VN G T LH +V++G+ ++ +LL+ GAD N DG AL
Sbjct: 547 DVNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCAL 592
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 27 TQELQSLLQNMTNCEFNVNSFGPEGQTALHQSV 59
T+ Q+LLQ NC + SF G + HQ++
Sbjct: 101 TERNQALLQTRKNCSMFIGSFRQSGLSLNHQNI 133
>gi|38683799 ankyrin repeat domain 13 [Homo sapiens]
Length = 590
Score = 51.6 bits (122), Expect = 1e-07
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 22 VRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLAN 81
V K + ++L+ LQ NV + P G+T LH +V G+LE ++L++ AD+ N
Sbjct: 17 VWKNDYRQLEKELQGQ-----NVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKEN 71
Query: 82 RDGWSALHIAAFGGHQDIVLYLITKAKY 109
R GW+ LH A G ++V ++ Y
Sbjct: 72 RQGWTVLHEAVSTGDPEMVYTVLQHRDY 99
>gi|24233530 ankyrin repeat domain 44 [Homo sapiens]
Length = 919
Score = 50.4 bits (119), Expect = 3e-07
Identities = 26/62 (41%), Positives = 40/62 (64%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
+VN G+TALH + ++G++E+V LL+ GA+I ++ ALH AA+ GH D+V
Sbjct: 107 SVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVAL 166
Query: 103 LI 104
LI
Sbjct: 167 LI 168
Score = 48.5 bits (114), Expect = 1e-06
Identities = 21/62 (33%), Positives = 40/62 (64%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
N+N+F + + ALH + G+L++V LL+ GA++ ++ G++ LH AA G ++V +
Sbjct: 140 NINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKH 199
Query: 103 LI 104
L+
Sbjct: 200 LL 201
Score = 42.4 bits (98), Expect = 8e-05
Identities = 20/73 (27%), Positives = 40/73 (54%)
Query: 32 SLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
++++++ N ++ G TALH + +G +V L+ +GA++ N +G++ LH A
Sbjct: 195 NVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFA 254
Query: 92 AFGGHQDIVLYLI 104
A H + L L+
Sbjct: 255 AASTHGALCLELL 267
Score = 41.6 bits (96), Expect = 1e-04
Identities = 22/64 (34%), Positives = 34/64 (53%)
Query: 42 FNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVL 101
F +++ G+T LH + GN+E +KLL GAD ++ G + LH AA H +
Sbjct: 371 FEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIE 430
Query: 102 YLIT 105
L+T
Sbjct: 431 TLVT 434
Score = 40.8 bits (94), Expect = 2e-04
Identities = 21/72 (29%), Positives = 40/72 (55%)
Query: 34 LQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAF 93
L+ + N +VN +G++ LH + + G + L++ G +I ++DG + LH+AA
Sbjct: 264 LELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAAR 323
Query: 94 GGHQDIVLYLIT 105
GH+ ++ L T
Sbjct: 324 YGHELLINTLRT 335
Score = 39.7 bits (91), Expect = 5e-04
Identities = 21/55 (38%), Positives = 31/55 (56%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLI 104
+G T LH + +G + +VK L+ G +I N G +ALHIA + G +V LI
Sbjct: 180 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 234
Score = 38.5 bits (88), Expect = 0.001
Identities = 22/86 (25%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
AV + + +Q L+++ + VN+ QT LH + + ++ ++++ + + ++
Sbjct: 56 AVASRSEEAVQVLIKHSAD----VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVS 111
Query: 81 NRDGWSALHIAAFGGHQDIVLYLITK 106
+R G +ALH AA GH ++V L+ K
Sbjct: 112 DRGGRTALHHAALNGHVEMVNLLLAK 137
Score = 37.7 bits (86), Expect = 0.002
Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
A G+ Q L+ LL+ TN F + G ++ LH + +G+ + +++L++ D+ +
Sbjct: 514 AAAYGHRQCLELLLER-TNSGFEESDSGAT-KSPLHLAAYNGHHQALEVLLQSLVDLDIR 571
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ G +AL +AAF GH + V LI
Sbjct: 572 DEKGRTALDLAAFKGHTECVEALI 595
Score = 37.4 bits (85), Expect = 0.003
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
AV G+ + LL+ E NV++ G TALH+ ++ G+ E V++L++ I
Sbjct: 652 AVAYGHIDAVSLLLEK----EANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCK 707
Query: 81 NRDGWSALHIAAFGGH 96
+ G + LH AA GH
Sbjct: 708 DSRGRTPLHYAAARGH 723
Score = 36.2 bits (82), Expect = 0.006
Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLA 80
+V G+T L+ LL+ N E V+ +GQT L +V G+++ V LL++ A++
Sbjct: 616 SVINGHTLCLRLLLEIADNPEA-VDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTV 674
Query: 81 NRDGWSALHIAAFGGHQDIVLYLI 104
+ G +ALH GH++ V L+
Sbjct: 675 DILGCTALHRGIMTGHEECVQMLL 698
Score = 33.9 bits (76), Expect = 0.029
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 44 VNSFGPEGQTALHQSVIDGNLELVKLLVKFG-ADIRLANRDGWSALHIAAFGGHQDIVLY 102
VN+ G+TAL + +G V +LV AD+ + ++D + LH+A GH+ L
Sbjct: 840 VNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALL 899
Query: 103 LITK 106
++ K
Sbjct: 900 ILDK 903
Score = 32.3 bits (72), Expect = 0.083
Identities = 18/62 (29%), Positives = 32/62 (51%)
Query: 43 NVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLY 102
+VN+ E +T LH + G+ E+++LL+ GA + + + LH A ++ V
Sbjct: 8 DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQV 67
Query: 103 LI 104
LI
Sbjct: 68 LI 69
Score = 32.3 bits (72), Expect = 0.083
Identities = 14/40 (35%), Positives = 26/40 (65%)
Query: 53 TALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
T LH++V + E V++L+K AD+ +++ + LH+AA
Sbjct: 51 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAA 90
Score = 30.4 bits (67), Expect = 0.32
Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 25 GNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDG 84
G Q+L+QN ++ +G T LH + G+ L+ L GAD
Sbjct: 292 GRFTRSQTLIQNGGE----IDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHS 347
Query: 85 WSALHIAAFGGHQDIVLYLIT 105
LH+AA H D L++
Sbjct: 348 MFPLHLAALNAHSDCCRKLLS 368
Score = 29.3 bits (64), Expect = 0.70
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 21 AVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD---I 77
A KG+T+ +++L+ + N +T LH SVI+G+ ++LL++ + +
Sbjct: 582 AAFKGHTECVEALINPGASIFVKDNV---TKRTPLHASVINGHTLCLRLLLEIADNPEAV 638
Query: 78 RLANRDGWSALHIAAFGGHQDIVLYLITK 106
+ + G + L +A GH D V L+ K
Sbjct: 639 DVKDAKGQTPLMLAVAYGHIDAVSLLLEK 667
Score = 28.1 bits (61), Expect = 1.6
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 51 GQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAA 92
G+T LH + + + ++ LV GA++ + G +ALH AA
Sbjct: 413 GRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAA 454
Score = 27.3 bits (59), Expect = 2.7
Identities = 13/49 (26%), Positives = 27/49 (55%)
Query: 55 LHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYL 103
LH + ++ + + + L+ G +I ++ G + LH AA GG+ + + L
Sbjct: 351 LHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
>gi|103471993 huntingtin interacting protein 14 [Homo sapiens]
Length = 632
Score = 50.4 bits (119), Expect = 3e-07
Identities = 26/61 (42%), Positives = 36/61 (59%)
Query: 48 GPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKA 107
G T LH + G+L +V L+K+GAD L + +G S +H+AA GH IV YLI K
Sbjct: 121 GDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG 180
Query: 108 K 108
+
Sbjct: 181 Q 181
Score = 34.7 bits (78), Expect = 0.017
Identities = 17/39 (43%), Positives = 26/39 (66%)
Query: 53 TALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIA 91
TALH +V+ GN ++ LL++ GA++ N G SAL +A
Sbjct: 227 TALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLA 265
Score = 30.4 bits (67), Expect = 0.32
Identities = 16/45 (35%), Positives = 25/45 (55%)
Query: 62 GNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITK 106
G E + LV+ G D+R +++ + LH AA D+V Y I+K
Sbjct: 68 GIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISK 112
Score = 27.7 bits (60), Expect = 2.0
Identities = 13/47 (27%), Positives = 26/47 (55%)
Query: 50 EGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGH 96
EG + +H + G+ +V L+ G D+ + +++G + L AA+ H
Sbjct: 156 EGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTH 202
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.131 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,777,767
Number of Sequences: 37866
Number of extensions: 130426
Number of successful extensions: 1918
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 355
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 293
Number of HSP's gapped (non-prelim): 1519
length of query: 114
length of database: 18,247,518
effective HSP length: 84
effective length of query: 30
effective length of database: 15,066,774
effective search space: 452003220
effective search space used: 452003220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.