Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 13376267
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13376267 MORN repeat containing 1 [Homo sapiens]
(497 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13376267 MORN repeat containing 1 [Homo sapiens] 1058 0.0
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens] 103 3e-22
gi|157502187 radial spoke head 10 homolog B [Homo sapiens] 103 3e-22
gi|50355990 MORN repeat containing 3 [Homo sapiens] 93 6e-19
gi|18254456 testis-specific gene A2 [Homo sapiens] 92 1e-18
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] 85 1e-16
gi|40316935 alsin isoform 1 [Homo sapiens] 79 1e-14
gi|21704283 junctophilin 3 [Homo sapiens] 72 2e-12
gi|149999376 MORN repeat containing 4 [Homo sapiens] 70 4e-12
gi|30520314 MORN repeat containing 4 [Homo sapiens] 70 4e-12
gi|21735575 junctophilin 1 [Homo sapiens] 67 5e-11
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 66 6e-11
gi|225690502 junctophilin 4 [Homo sapiens] 61 3e-09
gi|225690500 junctophilin 4 [Homo sapiens] 61 3e-09
gi|18139549 SET domain-containing protein 7 [Homo sapiens] 60 4e-09
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens] 54 3e-07
gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ... 54 3e-07
gi|224282170 MORN repeat containing 2 [Homo sapiens] 50 6e-06
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ... 49 1e-05
gi|116292174 fidgetin-like 2 [Homo sapiens] 40 0.004
gi|223278407 MORN repeat containing 5 [Homo sapiens] 40 0.004
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 38 0.024
gi|19718780 semaphorin 6B precursor [Homo sapiens] 37 0.054
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 35 0.12
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] 35 0.16
gi|23510368 homeobox D11 [Homo sapiens] 34 0.27
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 34 0.27
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 34 0.27
gi|20070205 ladinin 1 [Homo sapiens] 34 0.27
gi|238550198 synaptotagmin III [Homo sapiens] 33 0.46
>gi|13376267 MORN repeat containing 1 [Homo sapiens]
Length = 497
Score = 1058 bits (2735), Expect = 0.0
Identities = 497/497 (100%), Positives = 497/497 (100%)
Query: 1 MAAAGEGTPSSRGPRRDPPRRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGS 60
MAAAGEGTPSSRGPRRDPPRRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGS
Sbjct: 1 MAAAGEGTPSSRGPRRDPPRRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGS 60
Query: 61 YYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREG 120
YYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREG
Sbjct: 61 YYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREG 120
Query: 121 HGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKG 180
HGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKG
Sbjct: 121 HGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKG 180
Query: 181 QWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVNVQLL 240
QWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVNVQLL
Sbjct: 181 QWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVNVQLL 240
Query: 241 QDHGEIAKSESGRVLQISAGVRYVQLSAYSEVNFFKVDRDNQETLIQTPFGFECIPYPVS 300
QDHGEIAKSESGRVLQISAGVRYVQLSAYSEVNFFKVDRDNQETLIQTPFGFECIPYPVS
Sbjct: 241 QDHGEIAKSESGRVLQISAGVRYVQLSAYSEVNFFKVDRDNQETLIQTPFGFECIPYPVS 300
Query: 301 SPAAGVPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARGHAPHCPGACQRV 360
SPAAGVPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARGHAPHCPGACQRV
Sbjct: 301 SPAAGVPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARGHAPHCPGACQRV 360
Query: 361 EQGCAEFTDVLLGPPPPGYHPFLFLDSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRPEG 420
EQGCAEFTDVLLGPPPPGYHPFLFLDSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRPEG
Sbjct: 361 EQGCAEFTDVLLGPPPPGYHPFLFLDSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRPEG 420
Query: 421 RATEEQAAAAHLGEYVLMIRDVTTPPFLGRRLPPAFKHLRVVAKRAGQPPHVLEEGPEAS 480
RATEEQAAAAHLGEYVLMIRDVTTPPFLGRRLPPAFKHLRVVAKRAGQPPHVLEEGPEAS
Sbjct: 421 RATEEQAAAAHLGEYVLMIRDVTTPPFLGRRLPPAFKHLRVVAKRAGQPPHVLEEGPEAS 480
Query: 481 SSWQAAHSCTPEPPAPR 497
SSWQAAHSCTPEPPAPR
Sbjct: 481 SSWQAAHSCTPEPPAPR 497
>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
Length = 870
Score = 103 bits (258), Expect = 3e-22
Identities = 64/174 (36%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGY 98
YEGE G G G F+ G Y G F +G + G+G WA G + G FV P +
Sbjct: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWA-DGLKYEGDFVKNVPMNH 144
Query: 99 GVMEYKAGGCYEGEVSHGMREGHG-FLVDRDGQVYQGSFHDNKRHGPGQMLF-QNGD-KY 155
GV + G YEGEV +GMR G G F Y G + + KRHG G + + Q G Y
Sbjct: 145 GVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWY 204
Query: 156 DGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAH-CSGVTYYGLWING 208
+GDWV++ ++G G+ G+ Y+GQW ++ G G M + Y G W G
Sbjct: 205 EGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERG 258
Score = 92.8 bits (229), Expect = 6e-19
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 37/223 (16%)
Query: 25 NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGD 84
+G G Y++ + +YEG++ HG + DGS YEG V+G G G +
Sbjct: 119 HGQGTYIWADGL-KYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPV 177
Query: 85 TFSGQFVLGEPQGYGVMEYKAGGC--YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRH 142
++ G + G+ G G + Y G YEG+ +++G G + G +Y+G + DN RH
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237
Query: 143 GPGQMLF---------------QNG-------------------DKYDGDWVRDRRQGHG 168
G G+M + QNG ++Y G++V R G G
Sbjct: 238 GEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRG 297
Query: 169 VLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPA 211
A G+ Y G+W S+ G+G + +G Y G + N H A
Sbjct: 298 KFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIA 340
Score = 86.3 bits (212), Expect = 6e-17
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 11/154 (7%)
Query: 24 RNGYG-VYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWS 82
R+G G +Y YEG+W K G G +K G+ YEG + D GEGR W +
Sbjct: 188 RHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTT 247
Query: 83 GDTFSGQFVLGEPQGYGV----------MEYKAGGCYEGEVSHGMREGHGFLVDRDGQVY 132
+ ++G++ G G+G +Y Y GE +G R G G G +Y
Sbjct: 248 NEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMY 307
Query: 133 QGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQG 166
G + NK+HG G++ F+NG Y+G + D G
Sbjct: 308 DGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
Score = 62.0 bits (149), Expect = 1e-09
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 3/126 (2%)
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143
+++ G+ V G +G G ++ G Y G S G+ G G + DG Y+G F N
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
Query: 144 PGQMLFQNGDKYDGDWVRDRRQGHGVLRCA-DGSTYKGQWHSDVFSGLGSMAHCSGVT-- 200
G + +G Y+G+ V R G G+ +C+ +Y G W + G GS+ + T
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCW 203
Query: 201 YYGLWI 206
Y G W+
Sbjct: 204 YEGDWV 209
Score = 35.0 bits (79), Expect = 0.16
Identities = 16/58 (27%), Positives = 27/58 (46%)
Query: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHP 210
+ Y+G+ VR +G G G TY+G + + G G+ G+ Y G ++ P
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP 141
>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
Length = 870
Score = 103 bits (258), Expect = 3e-22
Identities = 64/174 (36%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGY 98
YEGE G G G F+ G Y G F +G + G+G WA G + G FV P +
Sbjct: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWA-DGLKYEGDFVKNVPMNH 144
Query: 99 GVMEYKAGGCYEGEVSHGMREGHG-FLVDRDGQVYQGSFHDNKRHGPGQMLF-QNGD-KY 155
GV + G YEGEV +GMR G G F Y G + + KRHG G + + Q G Y
Sbjct: 145 GVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWY 204
Query: 156 DGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAH-CSGVTYYGLWING 208
+GDWV++ ++G G+ G+ Y+GQW ++ G G M + Y G W G
Sbjct: 205 EGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERG 258
Score = 92.8 bits (229), Expect = 6e-19
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 37/223 (16%)
Query: 25 NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGD 84
+G G Y++ + +YEG++ HG + DGS YEG V+G G G +
Sbjct: 119 HGQGTYIWADGL-KYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPV 177
Query: 85 TFSGQFVLGEPQGYGVMEYKAGGC--YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRH 142
++ G + G+ G G + Y G YEG+ +++G G + G +Y+G + DN RH
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237
Query: 143 GPGQMLF---------------QNG-------------------DKYDGDWVRDRRQGHG 168
G G+M + QNG ++Y G++V R G G
Sbjct: 238 GEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRG 297
Query: 169 VLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPA 211
A G+ Y G+W S+ G+G + +G Y G + N H A
Sbjct: 298 KFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIA 340
Score = 86.3 bits (212), Expect = 6e-17
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 11/154 (7%)
Query: 24 RNGYG-VYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWS 82
R+G G +Y YEG+W K G G +K G+ YEG + D GEGR W +
Sbjct: 188 RHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTT 247
Query: 83 GDTFSGQFVLGEPQGYGV----------MEYKAGGCYEGEVSHGMREGHGFLVDRDGQVY 132
+ ++G++ G G+G +Y Y GE +G R G G G +Y
Sbjct: 248 NEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMY 307
Query: 133 QGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQG 166
G + NK+HG G++ F+NG Y+G + D G
Sbjct: 308 DGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
Score = 62.0 bits (149), Expect = 1e-09
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 3/126 (2%)
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143
+++ G+ V G +G G ++ G Y G S G+ G G + DG Y+G F N
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
Query: 144 PGQMLFQNGDKYDGDWVRDRRQGHGVLRCA-DGSTYKGQWHSDVFSGLGSMAHCSGVT-- 200
G + +G Y+G+ V R G G+ +C+ +Y G W + G GS+ + T
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCW 203
Query: 201 YYGLWI 206
Y G W+
Sbjct: 204 YEGDWV 209
Score = 35.0 bits (79), Expect = 0.16
Identities = 16/58 (27%), Positives = 27/58 (46%)
Query: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHP 210
+ Y+G+ VR +G G G TY+G + + G G+ G+ Y G ++ P
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP 141
>gi|50355990 MORN repeat containing 3 [Homo sapiens]
Length = 240
Score = 92.8 bits (229), Expect = 6e-19
Identities = 61/214 (28%), Positives = 101/214 (47%), Gaps = 12/214 (5%)
Query: 44 KAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVM-- 101
KA R ++ +G YY G + D G+G + W G + G + G+ GYG +
Sbjct: 20 KAQRNGLRSQVYAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSL 79
Query: 102 -EYKAGGC---YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDG 157
+ + G C Y G + G+G + Y+G + ++R G G+M + NGD Y+G
Sbjct: 80 PDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEG 139
Query: 158 DWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCS-GVTYYGLWINGHPAEQATR 216
W D+ G G+LR +G+ Y+G W + +G G H G + G W++ + A+ T
Sbjct: 140 QWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWVD-NMAKCGTM 198
Query: 217 IVILGPEVMEVAQGSPFSV-NVQLLQDHGEIAKS 249
I E E Q F + V++L G +A++
Sbjct: 199 IDFGRDEAPEPTQ---FPIPEVKILDPDGVLAEA 229
Score = 71.6 bits (174), Expect = 2e-12
Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 7/122 (5%)
Query: 24 RNGYGVYVYPNSFFR-----YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRH 78
R+GYG P+ Y G WK +K G+G F YYEG + + +G GR +
Sbjct: 71 RDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMY 130
Query: 79 WAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRD-GQVYQGSFH 137
++ +GD + GQ+ +P G G++ K G YEG GM+ G G D GQ+++G +
Sbjct: 131 YS-NGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWV 189
Query: 138 DN 139
DN
Sbjct: 190 DN 191
>gi|18254456 testis-specific gene A2 [Homo sapiens]
Length = 309
Score = 92.0 bits (227), Expect = 1e-18
Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 83 GDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRH 142
G+ G+ GE G G G YEG G R G G ++G Y G + NK+H
Sbjct: 18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKH 77
Query: 143 GPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHC-SGVTY 201
G G ++ +G +Y+G+W D R GHGV + TY G+W + G G+ + +G Y
Sbjct: 78 GQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKY 137
Query: 202 YGLWING 208
G W+NG
Sbjct: 138 VGTWVNG 144
Score = 89.7 bits (221), Expect = 5e-18
Identities = 52/166 (31%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 59 GSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMR 118
G Y G GE G GR +GDT+ G + G+ G G+ ++K G Y GE +
Sbjct: 18 GEYEGGRNEAGERHGRGRARLP-NGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKK 76
Query: 119 EGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCAD-GST 177
G G + DG Y+G + ++ RHG G + N D Y G+W +R G G A+ GS
Sbjct: 77 HGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSK 136
Query: 178 YKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPE 223
Y G W + G + H + Y G ++N +P + +G E
Sbjct: 137 YVGTWVNGQQEGTAELIHLNH-RYQGKFLNKNPVGPGKYVFDVGCE 181
Score = 73.9 bits (180), Expect = 3e-13
Identities = 44/137 (32%), Positives = 73/137 (53%), Gaps = 4/137 (2%)
Query: 24 RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG 83
R+G G+Y + N RY GE+ +KHG G ++ DGS YEG + + G G ++ +
Sbjct: 53 RHGQGIYKFKNGA-RYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYI-NN 110
Query: 84 DTFSGQFVLGEPQGYGVMEY-KAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRH 142
DT++G++ + G G Y + G Y G +G +EG L+ + + YQG F +
Sbjct: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHR-YQGKFLNKNPV 169
Query: 143 GPGQMLFQNGDKYDGDW 159
GPG+ +F G + G++
Sbjct: 170 GPGKYVFDVGCEQHGEY 186
Score = 72.8 bits (177), Expect = 7e-13
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 26/144 (18%)
Query: 24 RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG 83
R+G G PN YEG ++ G++HG G FK+G+ Y
Sbjct: 30 RHGRGRARLPNGD-TYEGSYEFGKRHGQGIYKFKNGARY--------------------- 67
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143
G++V + G G Y G YEGE ++ +R GHG + Y G + ++RHG
Sbjct: 68 ---IGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHG 124
Query: 144 PGQMLF-QNGDKYDGDWVRDRRQG 166
G L+ + G KY G WV +++G
Sbjct: 125 QGTYLYAETGSKYVGTWVNGQQEG 148
>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
Length = 953
Score = 85.1 bits (209), Expect = 1e-16
Identities = 62/203 (30%), Positives = 86/203 (42%), Gaps = 33/203 (16%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG----DTFSGQFVLGE 94
YEGEW GR HG G L + DG + G F G G G R + D + + G
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
Query: 95 PQGYGVMEYKAGGCYEGEVSHGMREGHGFL-------------------------VDRDG 129
GYG+ EY Y+G G+R G G L ++ DG
Sbjct: 418 MCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDG 477
Query: 130 ---QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDV 186
+ Y G + +RHGPG M+ Q G Y G + D+ G G+L D S Y+G + D+
Sbjct: 478 DRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDL 537
Query: 187 -FSGLGSMAHCSGVTYYGLWING 208
G G + +G T G + +G
Sbjct: 538 TLMGKGKVTFPNGFTLEGSFGSG 560
Score = 71.6 bits (174), Expect = 2e-12
Identities = 55/184 (29%), Positives = 84/184 (45%), Gaps = 13/184 (7%)
Query: 25 NGYGVYVYPNS----FFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEG---RR 77
+G+G+ + P + F Y+ W+ G G+G + Y+G F +G G G
Sbjct: 391 HGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESG 450
Query: 78 HWAWSGDTFSGQFVLGEPQGYGVME-YKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSF 136
A ++G + G+ GYG+ E G Y G G R G G +V + G YQG+F
Sbjct: 451 PQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTF 510
Query: 137 HDNKRHGPGQMLFQNGDKYDGDWVRD-RRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAH 195
+K GPG +L ++ Y+G + RD G G + +G T +G + SG G H
Sbjct: 511 QADKTVGPGILLSEDDSLYEGTFTRDLTLMGKGKVTFPNGFTLEGSFG----SGAGRGLH 566
Query: 196 CSGV 199
GV
Sbjct: 567 TQGV 570
Score = 55.1 bits (131), Expect = 1e-07
Identities = 41/154 (26%), Positives = 63/154 (40%), Gaps = 37/154 (24%)
Query: 85 TFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLV---------------DRDG 129
T+ G++ G P G G +++ G + G G+ G G + R+G
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
Query: 130 -------------QVYQGSFHDNKRHGPGQMLFQNGD------KYDGDWVRDRRQGHGVL 170
+VY+G F + RHG G + ++G +Y G W R +R G+G+
Sbjct: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFG--VLESGPQAPQPFRYTGHWERGQRSGYGIE 474
Query: 171 RCAD-GSTYKGQWHSDVFSGLGSMAHCSGVTYYG 203
D G Y G W + G G M +GV Y G
Sbjct: 475 EDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQG 508
Score = 42.7 bits (99), Expect = 8e-04
Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 6/103 (5%)
Query: 21 RPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEG---RR 77
R R+GYG+ + RY G W+AG++HG G ++ + G Y+G F + G G
Sbjct: 465 RGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSE 524
Query: 78 HWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREG 120
+ TF+ L G G + + G EG G G
Sbjct: 525 DDSLYEGTFTRDLTL---MGKGKVTFPNGFTLEGSFGSGAGRG 564
>gi|40316935 alsin isoform 1 [Homo sapiens]
Length = 1657
Score = 78.6 bits (192), Expect = 1e-14
Identities = 56/177 (31%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG----DTFSGQFVLGE 94
Y+G W +G+ HG G L + DG Y G F +G G G D + G + G+
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108
Query: 95 PQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQV-------YQGSFHDNKRHGPGQM 147
G GV Y +G +EG MR GHG L R G++ + G + +K+ G G
Sbjct: 1109 MCGQGVYSYASGEVFEGCFQDNMRHGHGLL--RSGKLTSSSPSMFIGQWVMDKKAGYGVF 1166
Query: 148 L-FQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYG 203
G+KY G W D QG+GV+ G Y+G +H + G G + Y G
Sbjct: 1167 DDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEG 1223
Score = 68.9 bits (167), Expect = 1e-11
Identities = 43/159 (27%), Positives = 69/159 (43%), Gaps = 39/159 (24%)
Query: 85 TFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGH----------------------- 121
T+ G+++ G+P G GV+++ G Y G +G+ +G+
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEG 1107
Query: 122 -----GFLVDRDGQVYQGSFHDNKRHG-----PGQMLFQNGDKYDGDWVRDRRQGHGVL- 170
G G+V++G F DN RHG G++ + + G WV D++ G+GV
Sbjct: 1108 KMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFD 1167
Query: 171 RCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGH 209
G Y G W DV G G + VT +GL+ G+
Sbjct: 1168 DITRGEKYMGMWQDDVCQGNGVV-----VTQFGLYYEGN 1201
Score = 64.7 bits (156), Expect = 2e-10
Identities = 53/192 (27%), Positives = 72/192 (37%), Gaps = 41/192 (21%)
Query: 7 GTPSSRGPRRDPP--------RRPPRNGYGVYVYPNSFFR----YEGEWKAGRKHGHGKL 54
G P RG + P R +GYG Y PN Y G WK G+ G G
Sbjct: 1056 GKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVY 1115
Query: 55 LFKDGSYYEGAFVDGEITGEGR----RHWAWSGDTFSGQFVLGEPQGYGVME-------- 102
+ G +EG F D G G + + S F GQ+V+ + GYGV +
Sbjct: 1116 SYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKY 1175
Query: 103 ----------------YKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDN-KRHGPG 145
+ G YEG G+G L+ D +Y+G F D+ G G
Sbjct: 1176 MGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKG 1235
Query: 146 QMLFQNGDKYDG 157
+ NGD +G
Sbjct: 1236 TLTMPNGDYIEG 1247
>gi|21704283 junctophilin 3 [Homo sapiens]
Length = 748
Score = 71.6 bits (174), Expect = 2e-12
Identities = 66/236 (27%), Positives = 91/236 (38%), Gaps = 35/236 (14%)
Query: 52 GKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEG 111
G+ F DG Y G + DG+ G G V P+G G Y G
Sbjct: 5 GRFNFDDGGSYCGGWEDGKAHGHG---------------VCTGPKGQGE--------YTG 41
Query: 112 EVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGD-KYDGDWVRDRRQGHGVL 170
SHG E G G YQG++ KRHG G L G Y G+W + +GV
Sbjct: 42 SWSHGF-EVLGVYTWPSGNTYQGTWAQGKRHGIG--LESKGKWVYKGEWTHGFKGRYGVR 98
Query: 171 RCA-DGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQ 229
CA +G+ Y+G W + + G G+ + G TY G W+ G R + P M
Sbjct: 99 ECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSV--PYGMAAVI 156
Query: 230 GSPFSVNVQLLQDHGEIAKSESGRVLQISAGVRYVQLSAYSEVNFFKVDRDNQETL 285
SP ++ L+ ++ +G L A A S F V + E L
Sbjct: 157 RSPLRTSINSLR-----SEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEIL 207
Score = 70.1 bits (170), Expect = 4e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 9/135 (6%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGS-YYEGAFVDG-EITGEGRRHWAW-SGDTFSGQFVLGEP 95
Y G W+ G+ HGHG G Y G++ G E+ G + W SG+T+ G + G+
Sbjct: 15 YCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGV----YTWPSGNTYQGTWAQGKR 70
Query: 96 QGYGVMEYKAGGCYEGEVSHGMREGHGFL-VDRDGQVYQGSFHDNKRHGPGQMLFQNGDK 154
G G +E K Y+GE +HG + +G +G Y+G++ + + G G + +G
Sbjct: 71 HGIG-LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGT 129
Query: 155 YDGDWVRDRRQGHGV 169
Y G WV RQG+GV
Sbjct: 130 YQGQWVGGMRQGYGV 144
Score = 60.5 bits (145), Expect = 4e-09
Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Query: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
GVY +P+ Y+G W G++HG G L K Y+G + G G R A +G +
Sbjct: 51 GVYTWPSGN-TYQGTWAQGKRHGIG-LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYE 108
Query: 88 GQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHG 122
G + G GYG Y GG Y+G+ GMR+G+G
Sbjct: 109 GTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYG 143
Score = 46.2 bits (108), Expect = 7e-05
Identities = 19/60 (31%), Positives = 35/60 (58%)
Query: 130 QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSG 189
+ Y G + ++KR G G +G KY+G+W +RR G+G + DG+ +G++ ++ G
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Score = 44.7 bits (104), Expect = 2e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 24 RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRH 78
R+G+GV + +YEGEW + R+HG+G + F DG+ EG + + G R++
Sbjct: 297 RSGFGVSQRSDGL-KYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKN 350
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/51 (37%), Positives = 27/51 (52%)
Query: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYG 203
+ Y G+W D+R G GV + +DG Y+G+W S+ G G M G G
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEG 336
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/51 (39%), Positives = 27/51 (52%)
Query: 109 YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159
Y GE + R G G DG Y+G + N+RHG G M F +G K +G +
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
Score = 39.3 bits (90), Expect = 0.008
Identities = 19/51 (37%), Positives = 26/51 (50%)
Query: 27 YGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRR 77
YGV + +YEG W G + G+G + DG Y+G +V G G G R
Sbjct: 95 YGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVR 145
Score = 36.2 bits (82), Expect = 0.071
Identities = 18/60 (30%), Positives = 31/60 (51%)
Query: 80 AWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDN 139
A + +T+ G++ + G+GV + G YEGE + R G+G + DG +G + N
Sbjct: 282 ATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN 341
Score = 30.4 bits (67), Expect = 3.9
Identities = 23/82 (28%), Positives = 29/82 (35%), Gaps = 24/82 (29%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGY 98
Y GEWK ++ G G DG YEG + RRH GY
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEW------ASNRRH------------------GY 323
Query: 99 GVMEYKAGGCYEGEVSHGMREG 120
G M + G EG+ + G
Sbjct: 324 GCMTFPDGTKEEGKYKQNILVG 345
Score = 30.0 bits (66), Expect = 5.1
Identities = 12/29 (41%), Positives = 15/29 (51%)
Query: 177 TYKGQWHSDVFSGLGSMAHCSGVTYYGLW 205
TY G+W +D SG G G+ Y G W
Sbjct: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEW 315
>gi|149999376 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 70.1 bits (170), Expect = 4e-12
Identities = 43/117 (36%), Positives = 59/117 (50%), Gaps = 6/117 (5%)
Query: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
G + Y +S Y GEWK GR+HG G+L+F DG Y G F +G G G ++ G +
Sbjct: 6 GSFTY-SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFS-DGSRYE 63
Query: 88 GQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQ----VYQGSFHDNK 140
G+F G+ G GV +EGE +G +G G L DG +G F +NK
Sbjct: 64 GEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
Score = 60.5 bits (145), Expect = 4e-09
Identities = 30/95 (31%), Positives = 48/95 (50%)
Query: 82 SGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
SG+ + G++ G G+G + + GG Y G +G+ G G L DG Y+G F K
Sbjct: 12 SGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKF 71
Query: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGS 176
+G G + + ++G++ R G G+L DGS
Sbjct: 72 NGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106
Score = 60.1 bits (144), Expect = 5e-09
Identities = 31/100 (31%), Positives = 49/100 (49%)
Query: 99 GVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
G Y +G Y GE G R G G L+ DG Y G F + +G G + F +G +Y+G+
Sbjct: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
Query: 159 WVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSG 198
+ + + G GV D T++G++ + G G + G
Sbjct: 66 FAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDG 105
Score = 60.1 bits (144), Expect = 5e-09
Identities = 28/80 (35%), Positives = 46/80 (57%)
Query: 129 GQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFS 188
G+ Y+G + + +RHG GQ++F +G Y G + G GVL +DGS Y+G++ F+
Sbjct: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFN 72
Query: 189 GLGSMAHCSGVTYYGLWING 208
G+G +T+ G + NG
Sbjct: 73 GVGVFIRYDNMTFEGEFKNG 92
Score = 53.5 bits (127), Expect = 4e-07
Identities = 23/64 (35%), Positives = 34/64 (53%)
Query: 145 GQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGL 204
G + +G++Y G+W RR G G L ADG TY G + + +F+G G + G Y G
Sbjct: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
Query: 205 WING 208
+ G
Sbjct: 66 FAQG 69
>gi|30520314 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 70.1 bits (170), Expect = 4e-12
Identities = 43/117 (36%), Positives = 59/117 (50%), Gaps = 6/117 (5%)
Query: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
G + Y +S Y GEWK GR+HG G+L+F DG Y G F +G G G ++ G +
Sbjct: 6 GSFTY-SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFS-DGSRYE 63
Query: 88 GQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQ----VYQGSFHDNK 140
G+F G+ G GV +EGE +G +G G L DG +G F +NK
Sbjct: 64 GEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNK 120
Score = 60.5 bits (145), Expect = 4e-09
Identities = 30/95 (31%), Positives = 48/95 (50%)
Query: 82 SGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
SG+ + G++ G G+G + + GG Y G +G+ G G L DG Y+G F K
Sbjct: 12 SGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKF 71
Query: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGS 176
+G G + + ++G++ R G G+L DGS
Sbjct: 72 NGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGS 106
Score = 60.1 bits (144), Expect = 5e-09
Identities = 31/100 (31%), Positives = 49/100 (49%)
Query: 99 GVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
G Y +G Y GE G R G G L+ DG Y G F + +G G + F +G +Y+G+
Sbjct: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
Query: 159 WVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSG 198
+ + + G GV D T++G++ + G G + G
Sbjct: 66 FAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDG 105
Score = 60.1 bits (144), Expect = 5e-09
Identities = 28/80 (35%), Positives = 46/80 (57%)
Query: 129 GQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFS 188
G+ Y+G + + +RHG GQ++F +G Y G + G GVL +DGS Y+G++ F+
Sbjct: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFN 72
Query: 189 GLGSMAHCSGVTYYGLWING 208
G+G +T+ G + NG
Sbjct: 73 GVGVFIRYDNMTFEGEFKNG 92
Score = 53.5 bits (127), Expect = 4e-07
Identities = 23/64 (35%), Positives = 34/64 (53%)
Query: 145 GQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGL 204
G + +G++Y G+W RR G G L ADG TY G + + +F+G G + G Y G
Sbjct: 6 GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65
Query: 205 WING 208
+ G
Sbjct: 66 FAQG 69
>gi|21735575 junctophilin 1 [Homo sapiens]
Length = 661
Score = 66.6 bits (161), Expect = 5e-11
Identities = 50/156 (32%), Positives = 68/156 (43%), Gaps = 30/156 (19%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGS-YYEGAFVDG-EITGEGRRHWAW-SGDTFSGQFVLGEP 95
Y G W+ G+ HGHG G Y G++ G E+ G + W SG+T+ G + G+
Sbjct: 14 YCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG----YTWPSGNTYQGYWAQGKR 69
Query: 96 QGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKY 155
G GV E K Y GE SHG + R+G Q L +Y
Sbjct: 70 HGLGV-ETKGKWMYRGEWSHGFKG---------------------RYGVRQSLCTPA-RY 106
Query: 156 DGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLG 191
+G W + G+GV DG TY+GQW + G G
Sbjct: 107 EGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
Score = 56.6 bits (135), Expect = 5e-08
Identities = 39/128 (30%), Positives = 57/128 (44%), Gaps = 4/128 (3%)
Query: 83 GDTFSGQFVLGEPQGYGVMEYKAG-GCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
G T+ G + G+ G+G+ G G Y G SHG G+ G YQG + KR
Sbjct: 11 GGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWP-SGNTYQGYWAQGKR 69
Query: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRC-ADGSTYKGQWHSDVFSGLGSMAHCSGVT 200
HG G + + Y G+W + +GV + + Y+G W + + G G + G T
Sbjct: 70 HGLG-VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGT 128
Query: 201 YYGLWING 208
Y G W G
Sbjct: 129 YQGQWAGG 136
Score = 51.2 bits (121), Expect = 2e-06
Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 29/147 (19%)
Query: 25 NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAW-SG 83
+G+G+ P Y G W HG E+ G + W SG
Sbjct: 24 HGHGICTGPKGQGEYSGSW----SHGF------------------EVVG----GYTWPSG 57
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQV-YQGSFHDNKRH 142
+T+ G + G+ G GV E K Y GE SHG + +G Y+G++ + +
Sbjct: 58 NTYQGYWAQGKRHGLGV-ETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQD 116
Query: 143 GPGQMLFQNGDKYDGDWVRDRRQGHGV 169
G G + +G Y G W R G+GV
Sbjct: 117 GYGVETYGDGGTYQGQWAGGMRHGYGV 143
Score = 47.0 bits (110), Expect = 4e-05
Identities = 19/57 (33%), Positives = 35/57 (61%)
Query: 130 QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDV 186
+ Y G + ++KR+G G NG KY+G+W ++R G+G DGS +G++ +++
Sbjct: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
Score = 44.3 bits (103), Expect = 3e-04
Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 24 RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAF 66
RNG+GV N +YEGEW ++HG+G +F DGS EG +
Sbjct: 290 RNGFGVSERSNGM-KYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 2/65 (3%)
Query: 145 GQMLFQNGDKYDGDWVRDRRQGHGVLRCADGS-TYKGQWHSDVFSGLGSMAHCSGVTYYG 203
G+ F +G Y G W + GHG+ G Y G W S F +G SG TY G
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSW-SHGFEVVGGYTWPSGNTYQG 62
Query: 204 LWING 208
W G
Sbjct: 63 YWAQG 67
Score = 40.8 bits (94), Expect = 0.003
Identities = 19/51 (37%), Positives = 28/51 (54%)
Query: 109 YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159
Y GE + R G G +G Y+G + +NKRHG G +F +G K +G +
Sbjct: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/60 (33%), Positives = 33/60 (55%)
Query: 80 AWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDN 139
A + +T+ G++ + G+GV E G YEGE ++ R G+G V DG +G + +N
Sbjct: 275 ATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
Score = 37.4 bits (85), Expect = 0.032
Identities = 17/55 (30%), Positives = 27/55 (49%)
Query: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWIN 207
+ Y G+W D+R G GV ++G Y+G+W ++ G G G G + N
Sbjct: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
Score = 35.8 bits (81), Expect = 0.092
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 27 YGVYVYPNSFFRYEGEWKAGRKHGHG-KLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDT 85
+G+ V + Y GEW G K +G + + YEG + +G G G + G T
Sbjct: 70 HGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYG-DGGT 128
Query: 86 FSGQFVLGEPQGYGVME 102
+ GQ+ G GYGV +
Sbjct: 129 YQGQWAGGMRHGYGVRQ 145
Score = 29.3 bits (64), Expect = 8.7
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEG 75
Y GEWK +++G G +G YEG + + + G G
Sbjct: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYG 317
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 30/156 (19%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGS-YYEGAFVDG-EITGEGRRHWAW-SGDTFSGQFVLGEP 95
Y G W+ G+ HGHG G Y G++ G E+ G + W SG+TF G + G+
Sbjct: 14 YCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGV----YTWPSGNTFEGYWSQGKR 69
Query: 96 QGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKY 155
G G+ E K Y+GE +HG + +G + Q S +G KY
Sbjct: 70 HGLGI-ETKGRWLYKGEWTHGFKGRYG--------IRQSS--------------SSGAKY 106
Query: 156 DGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLG 191
+G W + G+G ADG TY+GQ+ + + G G
Sbjct: 107 EGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYG 142
Score = 60.1 bits (144), Expect = 5e-09
Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Query: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
GVY +P+ +EG W G++HG G + K Y+G + G G R + SG +
Sbjct: 50 GVYTWPSGN-TFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYE 107
Query: 88 GQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHG 122
G + G GYG Y GG Y+G+ ++GMR G+G
Sbjct: 108 GTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYG 142
Score = 53.5 bits (127), Expect = 4e-07
Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 6/161 (3%)
Query: 83 GDTFSGQFVLGEPQGYGVMEYKAG-GCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
G + G + G+ G+G+ G G Y G + G E G G ++G + KR
Sbjct: 11 GGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKR 69
Query: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCAD-GSTYKGQWHSDVFSGLGSMAHCSGVT 200
HG G + + Y G+W + +G+ + + G+ Y+G W++ + G G+ + G T
Sbjct: 70 HGLG-IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGT 128
Query: 201 YYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVNVQLLQ 241
Y G + NG R + P M V SP ++ L+
Sbjct: 129 YQGQFTNGMRHGYGVRQSV--PYGMAVVVRSPLRTSLSSLR 167
Score = 48.5 bits (114), Expect = 1e-05
Identities = 78/344 (22%), Positives = 123/344 (35%), Gaps = 41/344 (11%)
Query: 111 GEVSHGMREGHGFLVDRDG---QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGH 167
GE + G E F D D + Y G + ++KR G G +G +Y+G+W+ + R G+
Sbjct: 267 GEAAEGADEAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGY 326
Query: 168 GVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEV 227
G DG +G++ +V + H E A R + + E+
Sbjct: 327 GCTTLPDGHREEGKYRHNVLVKDTKRRMLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEI 386
Query: 228 A--QGSPFSVNVQLLQDHGEIAKSESGRVLQISAGVR---YVQLSAYSEVNFFKVDRDNQ 282
A + S + + A ES ++ + Y Y + + +N
Sbjct: 387 AASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENS 446
Query: 283 ETLIQTP---FGFECIPYP-----------VSSPAAGVPGPRAAKGGAEADVPLPRGDLE 328
E+L++ P G +P P P G P P + P D
Sbjct: 447 ESLLEPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGL 506
Query: 329 LHLGALHGQEDTPGGLLARGHAPHCPGACQRVEQGCAE---FTDVLLGPPPPGYHPFLFL 385
L GA +G+ P G +R P GA +R A + L PP P P + L
Sbjct: 507 LSPGAWNGE---PSGEGSRSVTP-SEGAGRRSPARPATERMAIEALQAPPAPSREPEVAL 562
Query: 386 -DSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRPEGRATEEQAA 428
H A R TPP + PP +PE + ++A
Sbjct: 563 YQGYHSYA---------VRTTPP--EPPPFEDQPEPEVSGSESA 595
Score = 45.4 bits (106), Expect = 1e-04
Identities = 91/361 (25%), Positives = 125/361 (34%), Gaps = 89/361 (24%)
Query: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAE 212
+ Y G+W D+R G GV + G Y+G+W ++ G G C+ + +GH E
Sbjct: 289 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYG----CTTLP------DGHREE 338
Query: 213 QATRIVILGPEVMEVAQGSPFSVNVQLLQDHGEIAKSESGRVLQISAGVRYVQLSAYSEV 272
R H + K R+LQ+ +
Sbjct: 339 GKYR--------------------------HNVLVKDTKRRMLQLKSN------------ 360
Query: 273 NFFKVDRDNQETLIQTPFGFECIPYPVSSPAAGVPGPRAAKGGAEADVPLPRGDLELHLG 332
KV R E ++ I + AA AK A L
Sbjct: 361 ---KV-RQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAAN------- 409
Query: 333 ALHGQEDTPGGLLARGHAP--HCPGA---CQRVEQGCAEFTDVLLGPPPPGY------HP 381
QE LAR AP + PG +R+ Q E ++ LL PP G P
Sbjct: 410 ----QESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAGAAGLPQP 465
Query: 382 FLFLDSLHKKAGGRSRGGL-HPRGTPPTAQEPPGGSRPEGRATEEQAAAAHLGEYVLMIR 440
LH++ R GG P GTPP + P G +G + GE R
Sbjct: 466 PRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGE---GSR 522
Query: 441 DVTTPPFLGRRLP--PAFKHLRVVAKRAGQPPHVLEEGPEASSSWQAAHS-----CTPEP 493
VT GRR P PA + + + A +A PP E PE + +Q HS PEP
Sbjct: 523 SVTPSEGAGRRSPARPATERMAIEALQA--PPAPSRE-PEV-ALYQGYHSYAVRTTPPEP 578
Query: 494 P 494
P
Sbjct: 579 P 579
Score = 43.1 bits (100), Expect = 6e-04
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 27 YGVYVYPNSFFRYEGEWKAGRKHGHG-KLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDT 85
+G+ + + Y+GEW G K +G + G+ YEG + +G G G +A G T
Sbjct: 70 HGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYA-DGGT 128
Query: 86 FSGQFVLGEPQGYGVME 102
+ GQF G GYGV +
Sbjct: 129 YQGQFTNGMRHGYGVRQ 145
Score = 37.4 bits (85), Expect = 0.032
Identities = 19/60 (31%), Positives = 31/60 (51%)
Query: 80 AWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDN 139
A + +T+ G++ + G+GV E +G YEGE +R G+G DG +G + N
Sbjct: 285 ATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHN 344
Score = 35.8 bits (81), Expect = 0.092
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 24 RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRR 77
R+G+GV +S RYEGEW +HG+G DG EG + + + +R
Sbjct: 300 RSGFGVSER-SSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKR 352
Score = 33.5 bits (75), Expect = 0.46
Identities = 17/51 (33%), Positives = 24/51 (47%)
Query: 109 YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159
Y GE + R G G G Y+G + DN RHG G +G + +G +
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKY 341
>gi|225690502 junctophilin 4 [Homo sapiens]
Length = 628
Score = 60.8 bits (146), Expect = 3e-09
Identities = 42/137 (30%), Positives = 59/137 (43%), Gaps = 14/137 (10%)
Query: 39 YEGEWKAGRKHGHGKLLFK------DGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVL 92
Y G W+AGR HG+G G + G G TG G G ++ G +
Sbjct: 15 YVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPG-------GHSYQGHWQQ 67
Query: 93 GEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNG 152
G+ +G GV E K+ Y GE G++ G G Y G + D + G G + +G
Sbjct: 68 GKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDG 126
Query: 153 DKYDGDWVRDRRQGHGV 169
Y G W +R G+GV
Sbjct: 127 GTYQGQWQAGKRHGYGV 143
Score = 57.0 bits (136), Expect = 4e-08
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 4/141 (2%)
Query: 52 GKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEG 111
GK F DG Y G + G G G + +SG + G + GV G Y+G
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGF-ESLGVFTGPGGHSYQG 63
Query: 112 EVSHGMREGHGFLVDRDGQ-VYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVL 170
G REG G V+R + Y+G + + G +G +Y G W + G+G
Sbjct: 64 HWQQGKREGLG--VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE 121
Query: 171 RCADGSTYKGQWHSDVFSGLG 191
+DG TY+GQW + G G
Sbjct: 122 TYSDGGTYQGQWQAGKRHGYG 142
Score = 56.6 bits (135), Expect = 5e-08
Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 3/127 (2%)
Query: 83 GDTFSGQFVLGEPQGYGVMEYK-AGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
G + G + G GYGV A G Y G +HG E G G YQG + KR
Sbjct: 12 GGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKR 70
Query: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTY 201
G G + ++ Y G+W+ + GV G Y G W G G+ + G TY
Sbjct: 71 EGLG-VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTY 129
Query: 202 YGLWING 208
G W G
Sbjct: 130 QGQWQAG 136
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/122 (32%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 25 NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEG-RRHWAWSG 83
+GYGV P + Y G W G + G G Y+G + G+ G G R W
Sbjct: 25 HGYGVCTGPGAQGEYSGCWAHGFE-SLGVFTGPGGHSYQGHWQQGKREGLGVERKSRW-- 81
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143
T+ G+++ G GV E +G Y G G ++G+G DG YQG + KRHG
Sbjct: 82 -TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHG 140
Query: 144 PG 145
G
Sbjct: 141 YG 142
Score = 45.1 bits (105), Expect = 2e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 20 RRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGR 76
R R+G+GV N RYEGEW R+HG+G+ DGS EG + + GR
Sbjct: 287 RADRRSGFGVSQRSNGL-RYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGR 342
Score = 43.1 bits (100), Expect = 6e-04
Identities = 19/53 (35%), Positives = 32/53 (60%)
Query: 130 QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQW 182
+VY G + ++R G G NG +Y+G+W+ +RR G+G DGS +G++
Sbjct: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKY 332
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
G+ V S + Y GEW G K G G Y G + DG G G ++ G T+
Sbjct: 72 GLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYS-DGGTYQ 130
Query: 88 GQFVLGEPQGYGVME 102
GQ+ G+ GYGV +
Sbjct: 131 GQWQAGKRHGYGVRQ 145
Score = 37.4 bits (85), Expect = 0.032
Identities = 22/72 (30%), Positives = 35/72 (48%)
Query: 100 VMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159
++E A Y GE R G G +G Y+G + N+RHG G+ +G + +G +
Sbjct: 273 LIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKY 332
Query: 160 VRDRRQGHGVLR 171
R+R G +R
Sbjct: 333 KRNRLVHGGRVR 344
Score = 36.2 bits (82), Expect = 0.071
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 155 YDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSG 198
Y G+W DRR G GV + ++G Y+G+W + G G G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDG 325
Score = 34.3 bits (77), Expect = 0.27
Identities = 20/66 (30%), Positives = 28/66 (42%)
Query: 11 SRGPRRDPPRRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGE 70
S GP PP + ++ Y GEW+A R+ G G +G YEG ++
Sbjct: 254 STGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNR 313
Query: 71 ITGEGR 76
G GR
Sbjct: 314 RHGYGR 319
Score = 32.3 bits (72), Expect = 1.0
Identities = 16/57 (28%), Positives = 27/57 (47%)
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNK 140
+ ++G++ G+GV + G YEGE R G+G DG +G + N+
Sbjct: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
Score = 29.6 bits (65), Expect = 6.6
Identities = 11/29 (37%), Positives = 16/29 (55%)
Query: 178 YKGQWHSDVFSGLGSMAHCSGVTYYGLWI 206
Y G+W +D SG G +G+ Y G W+
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWL 310
>gi|225690500 junctophilin 4 [Homo sapiens]
Length = 628
Score = 60.8 bits (146), Expect = 3e-09
Identities = 42/137 (30%), Positives = 59/137 (43%), Gaps = 14/137 (10%)
Query: 39 YEGEWKAGRKHGHGKLLFK------DGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVL 92
Y G W+AGR HG+G G + G G TG G G ++ G +
Sbjct: 15 YVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPG-------GHSYQGHWQQ 67
Query: 93 GEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNG 152
G+ +G GV E K+ Y GE G++ G G Y G + D + G G + +G
Sbjct: 68 GKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDG 126
Query: 153 DKYDGDWVRDRRQGHGV 169
Y G W +R G+GV
Sbjct: 127 GTYQGQWQAGKRHGYGV 143
Score = 57.0 bits (136), Expect = 4e-08
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 4/141 (2%)
Query: 52 GKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEG 111
GK F DG Y G + G G G + +SG + G + GV G Y+G
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGF-ESLGVFTGPGGHSYQG 63
Query: 112 EVSHGMREGHGFLVDRDGQ-VYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVL 170
G REG G V+R + Y+G + + G +G +Y G W + G+G
Sbjct: 64 HWQQGKREGLG--VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE 121
Query: 171 RCADGSTYKGQWHSDVFSGLG 191
+DG TY+GQW + G G
Sbjct: 122 TYSDGGTYQGQWQAGKRHGYG 142
Score = 56.6 bits (135), Expect = 5e-08
Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 3/127 (2%)
Query: 83 GDTFSGQFVLGEPQGYGVMEYK-AGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
G + G + G GYGV A G Y G +HG E G G YQG + KR
Sbjct: 12 GGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKR 70
Query: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTY 201
G G + ++ Y G+W+ + GV G Y G W G G+ + G TY
Sbjct: 71 EGLG-VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTY 129
Query: 202 YGLWING 208
G W G
Sbjct: 130 QGQWQAG 136
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/122 (32%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 25 NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEG-RRHWAWSG 83
+GYGV P + Y G W G + G G Y+G + G+ G G R W
Sbjct: 25 HGYGVCTGPGAQGEYSGCWAHGFE-SLGVFTGPGGHSYQGHWQQGKREGLGVERKSRW-- 81
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143
T+ G+++ G GV E +G Y G G ++G+G DG YQG + KRHG
Sbjct: 82 -TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHG 140
Query: 144 PG 145
G
Sbjct: 141 YG 142
Score = 45.1 bits (105), Expect = 2e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 20 RRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGR 76
R R+G+GV N RYEGEW R+HG+G+ DGS EG + + GR
Sbjct: 287 RADRRSGFGVSQRSNGL-RYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGR 342
Score = 43.1 bits (100), Expect = 6e-04
Identities = 19/53 (35%), Positives = 32/53 (60%)
Query: 130 QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQW 182
+VY G + ++R G G NG +Y+G+W+ +RR G+G DGS +G++
Sbjct: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKY 332
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
G+ V S + Y GEW G K G G Y G + DG G G ++ G T+
Sbjct: 72 GLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYS-DGGTYQ 130
Query: 88 GQFVLGEPQGYGVME 102
GQ+ G+ GYGV +
Sbjct: 131 GQWQAGKRHGYGVRQ 145
Score = 37.4 bits (85), Expect = 0.032
Identities = 22/72 (30%), Positives = 35/72 (48%)
Query: 100 VMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159
++E A Y GE R G G +G Y+G + N+RHG G+ +G + +G +
Sbjct: 273 LIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKY 332
Query: 160 VRDRRQGHGVLR 171
R+R G +R
Sbjct: 333 KRNRLVHGGRVR 344
Score = 36.2 bits (82), Expect = 0.071
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 155 YDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSG 198
Y G+W DRR G GV + ++G Y+G+W + G G G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDG 325
Score = 34.3 bits (77), Expect = 0.27
Identities = 20/66 (30%), Positives = 28/66 (42%)
Query: 11 SRGPRRDPPRRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGE 70
S GP PP + ++ Y GEW+A R+ G G +G YEG ++
Sbjct: 254 STGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNR 313
Query: 71 ITGEGR 76
G GR
Sbjct: 314 RHGYGR 319
Score = 32.3 bits (72), Expect = 1.0
Identities = 16/57 (28%), Positives = 27/57 (47%)
Query: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNK 140
+ ++G++ G+GV + G YEGE R G+G DG +G + N+
Sbjct: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
Score = 29.6 bits (65), Expect = 6.6
Identities = 11/29 (37%), Positives = 16/29 (55%)
Query: 178 YKGQWHSDVFSGLGSMAHCSGVTYYGLWI 206
Y G+W +D SG G +G+ Y G W+
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWL 310
>gi|18139549 SET domain-containing protein 7 [Homo sapiens]
Length = 366
Score = 60.5 bits (145), Expect = 4e-09
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Query: 46 GRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKA 105
G HG + + +EG FV GE G G + + + G T G +V QG GV Y+
Sbjct: 20 GLPHGFCTVTYSSTDRFEGNFVHGEKNGRG-KFFFFDGSTLEGYYVDDALQGQGVYTYED 78
Query: 106 GGCYEGEVSHGMREGHGFLVDRDGQ-VYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
GG +G G G D DG+ +++G + DN RHG + + +G G+
Sbjct: 79 GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGE 132
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 6/125 (4%)
Query: 67 VDGEITGEGRRHWAW-----SGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGH 121
V+G + +G H S D F G FV GE G G + G EG +G
Sbjct: 12 VEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQ 71
Query: 122 GFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDK-YDGDWVRDRRQGHGVLRCADGSTYKG 180
G DG V QG++ D + +GP Q +G + G + + R G + DG + G
Sbjct: 72 GVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVG 131
Query: 181 QWHSD 185
+ + D
Sbjct: 132 EVNED 136
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 138 DNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCS 197
D HG + + + D+++G++V + G G DGST +G + D G G +
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
Query: 198 GVTYYGLWINGH---PAEQ 213
G G +++G PA++
Sbjct: 79 GGVLQGTYVDGELNGPAQE 97
Score = 37.4 bits (85), Expect = 0.032
Identities = 17/58 (29%), Positives = 30/58 (51%)
Query: 132 YQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSG 189
++G+F +++G G+ F +G +G +V D QG GV DG +G + +G
Sbjct: 36 FEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNG 93
>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
Length = 129
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/140 (30%), Positives = 62/140 (44%), Gaps = 30/140 (21%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGS-YYEGAFVDG-EITGEGRRHWAW-SGDTFSGQFVLGEP 95
Y G W+ G+ HGHG G Y G++ G E+ G + W SG+TF G + G+
Sbjct: 14 YCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGV----YTWPSGNTFEGYWSQGKR 69
Query: 96 QGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKY 155
G G+ E K Y+GE +HG + +G + Q S +G KY
Sbjct: 70 HGLGI-ETKGRWLYKGEWTHGFKGRYG--------IRQSS--------------SSGAKY 106
Query: 156 DGDWVRDRRQGHGVLRCADG 175
+G W + G+G ADG
Sbjct: 107 EGTWNNGLQDGYGTETYADG 126
Score = 43.5 bits (101), Expect = 4e-04
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 83 GDTFSGQFVLGEPQGYGVMEYKAG-GCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141
G + G + G+ G+G+ G G Y G + G E G G ++G + KR
Sbjct: 11 GGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKR 69
Query: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCAD-GSTYKGQWHSDVFSGLGSMAHCSG 198
HG G + + Y G+W + +G+ + + G+ Y+G W++ + G G+ + G
Sbjct: 70 HGLG-IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADG 126
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87
GVY +P+ +EG W G++HG G + K Y+G + G G R + SG +
Sbjct: 50 GVYTWPSGN-TFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYE 107
Query: 88 GQFVLGEPQGYGVMEYKAGG 107
G + G GYG Y GG
Sbjct: 108 GTWNNGLQDGYGTETYADGG 127
Score = 29.3 bits (64), Expect = 8.7
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 27 YGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDG 59
YG+ +S +YEG W G + G+G + DG
Sbjct: 94 YGIRQSSSSGAKYEGTWNNGLQDGYGTETYADG 126
>gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1
[Homo sapiens]
Length = 941
Score = 54.3 bits (129), Expect = 3e-07
Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 25/125 (20%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGY 98
Y+GE+ K G+GK + G Y G F G G W G +F+G F L +GY
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWP-DGSSFTGTFYLSHREGY 60
Query: 99 GVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
G M K +++QG + ++R GPG + +G + G
Sbjct: 61 GTMYMKT------------------------RLFQGLYKADQRFGPGVETYPDGSQDVGL 96
Query: 159 WVRDR 163
W R++
Sbjct: 97 WFREQ 101
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 109 YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHG 168
Y+GE M+ G+G G+ Y G F+ + HG G ++ +G + G + R+G+G
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61
Query: 169 VLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRI 217
+ ++G + +D G G + G GLW + T+I
Sbjct: 62 TMYMKT-RLFQGLYKADQRFGPGVETYPDGSQDVGLWFREQLIKLCTQI 109
Score = 47.8 bits (112), Expect = 2e-05
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Query: 86 FSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPG 145
+ G+F L GYG + G Y G+ G G + DG + G+F+ + R G G
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61
Query: 146 QMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQW 182
M + + G + D+R G GV DGS G W
Sbjct: 62 TM-YMKTRLFQGLYKADQRFGPGVETYPDGSQDVGLW 97
Score = 42.7 bits (99), Expect = 8e-04
Identities = 21/63 (33%), Positives = 32/63 (50%)
Query: 131 VYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGL 190
+YQG F N + G G+ + G+ Y G + RD G G DGS++ G ++ G
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGY 60
Query: 191 GSM 193
G+M
Sbjct: 61 GTM 63
>gi|224282170 MORN repeat containing 2 [Homo sapiens]
Length = 79
Score = 49.7 bits (117), Expect = 6e-06
Identities = 25/64 (39%), Positives = 32/64 (50%)
Query: 120 GHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYK 179
G G L G VY+G F DN HG G F NG KY G++ +R +G G G +
Sbjct: 3 GFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWS 62
Query: 180 GQWH 183
G +H
Sbjct: 63 GNFH 66
Score = 40.8 bits (94), Expect = 0.003
Identities = 19/63 (30%), Positives = 34/63 (53%)
Query: 97 GYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYD 156
G+G +E+ +G YEG+ M G G +G Y G+F++N+ G G+ G ++
Sbjct: 3 GFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWS 62
Query: 157 GDW 159
G++
Sbjct: 63 GNF 65
Score = 36.2 bits (82), Expect = 0.071
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGR----RHWAWSGD 84
YEG++K HG G F +G+ Y G F + + GEG + WSG+
Sbjct: 15 YEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWSGN 64
Score = 34.7 bits (78), Expect = 0.21
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 81 WSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFH 137
+SG + GQF G G + G Y G + EG G D G + G+FH
Sbjct: 10 FSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWSGNFH 66
Score = 31.2 bits (69), Expect = 2.3
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 166 GHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYG 203
G G L G+ Y+GQ+ ++F GLG+ +G Y G
Sbjct: 3 GFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTG 40
>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
[Homo sapiens]
Length = 717
Score = 48.5 bits (114), Expect = 1e-05
Identities = 22/72 (30%), Positives = 38/72 (52%)
Query: 99 GVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
GV E++ G Y+GE M+ G+G G+ Y G F+ + HG G ++ +G + G
Sbjct: 81 GVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGT 140
Query: 159 WVRDRRQGHGVL 170
+ R+G+G +
Sbjct: 141 FYLSHREGYGTM 152
Score = 46.6 bits (109), Expect = 5e-05
Identities = 23/67 (34%), Positives = 35/67 (52%)
Query: 127 RDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDV 186
+DG +YQG F N + G G+ + G+ Y G + RD G G DGS++ G ++
Sbjct: 86 QDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSH 145
Query: 187 FSGLGSM 193
G G+M
Sbjct: 146 REGYGTM 152
Score = 45.4 bits (106), Expect = 1e-04
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGY 98
Y+GE+ K G+GK + G Y G F G G W G +F+G F L +GY
Sbjct: 91 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWP-DGSSFTGTFYLSHREGY 149
Query: 99 GVMEYK 104
G M K
Sbjct: 150 GTMYMK 155
Score = 38.5 bits (88), Expect = 0.014
Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 74 EGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQ 133
+G + W G + G+F L GYG + G Y G+ G G + DG +
Sbjct: 80 QGVQEWQ-DGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFT 138
Query: 134 GSFHDNKRHGPGQM 147
G+F+ + R G G M
Sbjct: 139 GTFYLSHREGYGTM 152
Score = 35.4 bits (80), Expect = 0.12
Identities = 18/65 (27%), Positives = 32/65 (49%)
Query: 145 GQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGL 204
G +Q+G Y G++ + + G+G G +Y GQ++ D GLG+ G ++ G
Sbjct: 81 GVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGT 140
Query: 205 WINGH 209
+ H
Sbjct: 141 FYLSH 145
>gi|116292174 fidgetin-like 2 [Homo sapiens]
Length = 653
Score = 40.4 bits (93), Expect = 0.004
Identities = 50/168 (29%), Positives = 68/168 (40%), Gaps = 24/168 (14%)
Query: 266 LSAYSEVNFFKVDRDNQETLIQTPFGFECIPYPVSSPAAGVPGPRAAKGGAEADV---PL 322
L YS+ +F + + E P+ PYP++S G+PG ++ GG + P+
Sbjct: 80 LGGYSDASFLNGAKGDPE-----PWPGPEPPYPLASLHEGLPGTKSGGGGGSGALGGSPV 134
Query: 323 PRGDL--ELHLG-ALHGQEDTPGGLLARGHAPHCPGACQRVEQGCA----EFTDVLLGPP 375
G+L L+ G A G P G PG C + G A +L PP
Sbjct: 135 LAGNLPEPLYAGNACGGPSAAPEYAAGYGGGYLAPGYC--AQTGAALPPPPPAALLQPPP 192
Query: 376 PPGYHPFLFLDSLHKKAGGRSR----GGL-HPRGTPPTAQEPPGGSRP 418
PPGY P L + AGG + G L P G PP PG P
Sbjct: 193 PPGYGPSAPL--YNYPAGGYAAQPGYGALPPPPGPPPAPYLTPGLPAP 238
>gi|223278407 MORN repeat containing 5 [Homo sapiens]
Length = 161
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
Query: 101 MEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWV 160
MEY G Y GE G EG + +Y G D HG G + F +G +YD W
Sbjct: 1 MEY-TGSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIW- 58
Query: 161 RDRRQGHGVLRCADGSTY-KGQWH 183
+ G +DG Y + WH
Sbjct: 59 ENGLAIKGTYTFSDGLHYDEKNWH 82
Score = 35.8 bits (81), Expect = 0.092
Identities = 18/57 (31%), Positives = 27/57 (47%)
Query: 152 GDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWING 208
G KY G++V R +G + Y G+ +F G G++ SG Y +W NG
Sbjct: 5 GSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWENG 61
Score = 33.1 bits (74), Expect = 0.60
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 26 GYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDG 69
G Y+ P Y GE K G HG G L F GS Y+ + +G
Sbjct: 19 GKAKYILPTETI-YVGEMKDGMFHGEGTLYFPSGSQYDAIWENG 61
Score = 30.8 bits (68), Expect = 3.0
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 1/76 (1%)
Query: 81 WSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNK 140
++G + G++V G +G Y GE+ GM G G L G Y + +N
Sbjct: 3 YTGSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYD-AIWENG 61
Query: 141 RHGPGQMLFQNGDKYD 156
G F +G YD
Sbjct: 62 LAIKGTYTFSDGLHYD 77
Score = 29.6 bits (65), Expect = 6.6
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 38 RYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEG 75
+Y GE+ GR G K + + Y G DG GEG
Sbjct: 7 KYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEG 44
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 37.7 bits (86), Expect = 0.024
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 19/129 (14%)
Query: 40 EGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYG 99
EG+ + + G G+ ++G EG + E GEG G+ G+ GE +G G
Sbjct: 855 EGKGEEEGEEGEGE---EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE-GEEEGEG 910
Query: 100 VMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159
EGE G EG G + +G+ +G + + G G+ G++ +G+W
Sbjct: 911 ----------EGEEEEG--EGKG---EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955
Query: 160 VRDRRQGHG 168
+ +G G
Sbjct: 956 EGEEEEGEG 964
Score = 34.7 bits (78), Expect = 0.21
Identities = 36/153 (23%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 40 EGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYG 99
+GE + + G G+ +G EG + E G+G G+ G+ E +G G
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEE----GEEGEGEEEGEEGEGEG 878
Query: 100 VMEYKAG-GCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
E G G EGE EG G + +G + + G G+ + G++ +G+
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEG----EGEEEGEGEGEEEEGEGKGE---EEGEEGEGE 931
Query: 159 WVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLG 191
+ +G G +G +G+W + G G
Sbjct: 932 GEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG 964
Score = 30.8 bits (68), Expect = 3.0
Identities = 27/107 (25%), Positives = 40/107 (37%)
Query: 40 EGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYG 99
EGE + G G+ +G EG + E GEG G+ G+ E +G G
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988
Query: 100 VMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQ 146
E + G E G EG G + + +G + G G+
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE 1035
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 36.6 bits (83), Expect = 0.054
Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 3/105 (2%)
Query: 393 GGRSRGGLHPRGTPPTAQEPPGGSRPEGRATEEQAAAAHLGEYVLMIRDVTTPPFLGRRL 452
GGR GG G PP A P +AT Q L +L + T P +RL
Sbjct: 663 GGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQT--PLPQKRL 720
Query: 453 PPAFKHLRVVAKRAGQPPHVLEEGPEASSSWQAAHSCTPE-PPAP 496
P H + RA H L +SS A + PE PPAP
Sbjct: 721 PTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAP 765
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 35.4 bits (80), Expect = 0.12
Identities = 48/146 (32%), Positives = 54/146 (36%), Gaps = 26/146 (17%)
Query: 289 PFGFECIPYPVSSPAAGVPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARG 348
P G + P P S +G PGP A G A D+P P G + PG RG
Sbjct: 1225 PRGKKGPPGPPGS--SGPPGPAGATGRAPKDIPDP---------GPPGDQGPPGPDGPRG 1273
Query: 349 HAPHCPGACQRVEQGCAEFTDV-LLGPP-------PPGYHPFLFLDSLHKKAGGRS-RGG 399
AP PG V+ E D L GPP PPGY F D + G G
Sbjct: 1274 -APGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGP 1332
Query: 400 LHPRGTPPTAQE-----PPGGSRPEG 420
P G P E PPG P G
Sbjct: 1333 QGPHGFPGPPGEKGLPGPPGRKGPTG 1358
Score = 31.2 bits (69), Expect = 2.3
Identities = 45/161 (27%), Positives = 59/161 (36%), Gaps = 38/161 (23%)
Query: 286 IQTPFGFECIPYPVSSPAA-------GVPGPRAAKGGAEADVPLPRGDLELHLGALHGQE 338
IQ P G P P S G+PG R G E P PRG L G
Sbjct: 1110 IQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPG--EMGDPGPRG--------LQGDP 1159
Query: 339 DTPG--GLLARGHAPHCPGAC----QRVEQGCAEFTDVLLGPPPPGYHPFLFLDSLHKKA 392
PG G+ +P G Q+ +G + DV GPP P + + L +
Sbjct: 1160 GIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDV--GPPGP-----VGIPGLKGER 1212
Query: 393 GGRSRGGLHPRGT--------PPTAQEPPGGSRPEGRATEE 425
G G+ P G PP + PPG + GRA ++
Sbjct: 1213 GDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKD 1253
>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
Length = 1543
Score = 35.0 bits (79), Expect = 0.16
Identities = 45/161 (27%), Positives = 61/161 (37%), Gaps = 17/161 (10%)
Query: 265 QLSAYSEVNFFKVDRDNQETLIQTPFGFECIPYPVSSPAA---GVPGPRAAKGGAEADVP 321
QL+A + F ++ Q T I P PYP + PAA P P DV
Sbjct: 810 QLAAEGDAVVFSAPQEVQVTKINPP-----PPYPGTIPAAPTTAAPPPPLPPPQPPVDVC 864
Query: 322 LPRGDLELHLGALHGQEDTPGG---LLARGHAPHCPGACQ-RVEQGCAEFTDVLLGPPPP 377
L +GD L+ ++H Q TP G + + + C+ R C++ T L P P
Sbjct: 865 LKKGDFSLYPTSVHYQ--TPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTL---PGP 919
Query: 378 GYHPFLFLDSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRP 418
G L L + KK R T P P G P
Sbjct: 920 GSSATLRLTATEKKVPQPCSSATLNRLTVPRYSIPTGDPPP 960
>gi|23510368 homeobox D11 [Homo sapiens]
Length = 338
Score = 34.3 bits (77), Expect = 0.27
Identities = 32/90 (35%), Positives = 36/90 (40%), Gaps = 7/90 (7%)
Query: 393 GGRSRGGLHPRGTPPTAQEPPGGSRPEGRATEEQAAAAHLGEYVLMIRDVTTPPFLGRRL 452
GG S GG G P GG P A AAAA E M R++ P GRR
Sbjct: 80 GGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPP--AGRRP 137
Query: 453 PPAFKHLRVVAKRAGQPPHVLEEGPEASSS 482
FK V G PPH GP ++S
Sbjct: 138 DVLFKAPEPVCAAPG-PPH----GPAGAAS 162
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 34.3 bits (77), Expect = 0.27
Identities = 42/126 (33%), Positives = 55/126 (43%), Gaps = 25/126 (19%)
Query: 306 VPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARGHAPHCP--GACQRVEQG 363
+P P ++ GA + +PL RGD A+ G GG A G PH P + R E+G
Sbjct: 696 LPCPLCSREGACSCLPLERGD------AVAGW----GGHPALG-CPHPPEDDSSLRAERG 744
Query: 364 CAEFTDVLLGPPPPGYHPFLFLDSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRPEGRAT 423
D+ + PP P FLD L A + G RG PP PP P RA
Sbjct: 745 --SLADLPMAPPASA--PPEFLDPLMGAAAPQYPG----RGPPPAPPPPP----PPPRAP 792
Query: 424 EEQAAA 429
+ AA+
Sbjct: 793 ADPAAS 798
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 34.3 bits (77), Expect = 0.27
Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 12/84 (14%)
Query: 295 IPYPVSSPAAGVPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARGHAPHCP 354
+P P P G PGP KGG P P G L H + GG RG H P
Sbjct: 191 VPGPGPGPKQG-PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249
Query: 355 GACQRVEQGCAEFTDVLLGPPPPG 378
Q+ QG PPPG
Sbjct: 250 PYHQQHHQG-----------PPPG 262
>gi|20070205 ladinin 1 [Homo sapiens]
Length = 517
Score = 34.3 bits (77), Expect = 0.27
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 14/94 (14%)
Query: 407 PTAQEPPG-GSRPEGRATEEQAAAAHLGEYV--LMIRDVTTPPFLGRRLPPAFKHLRVVA 463
P AQEPP G P T+EQ A G+ + L + + PP + RLPP +++ +
Sbjct: 290 PLAQEPPASGGSPA--TTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPS 347
Query: 464 KRAGQPPHVLEEGPEASSSWQAAHSCTPEPPAPR 497
K EE + SS Q +S + + +PR
Sbjct: 348 K---------EEEADMSSPTQRTYSSSLKRSSPR 372
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 33.5 bits (75), Expect = 0.46
Identities = 32/126 (25%), Positives = 45/126 (35%), Gaps = 19/126 (15%)
Query: 330 HLGALHGQEDTPGGLLARGHAPHCPGACQRVEQGCAEFTDVLLGPPPPGYHPFLFLDSLH 389
HL A G GG HA H P + +E G +D P P Y L +DS
Sbjct: 116 HLAAGLGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDT----PEPSY---LDMDSYP 168
Query: 390 KKAGGRSRGGLHPRGTPPTAQE------------PPGGSRPEGRATEEQAAAAHLGEYVL 437
+ A G+ P T P P GG P ++ ++ + A Y
Sbjct: 169 EAAAAAVAAGVKPSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPA 228
Query: 438 MIRDVT 443
+ R +T
Sbjct: 229 LPRPLT 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.139 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,665,785
Number of Sequences: 37866
Number of extensions: 1639991
Number of successful extensions: 6270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 5695
Number of HSP's gapped (non-prelim): 444
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.