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Search of human proteins with 50659095
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
(783 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 1555 0.0
gi|13129006 nucleolar protein GU2 [Homo sapiens] 818 0.0
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 206 9e-53
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 206 9e-53
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 206 9e-53
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 204 3e-52
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 204 3e-52
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 203 4e-52
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 198 1e-50
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 198 2e-50
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 194 3e-49
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 189 7e-48
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 188 2e-47
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 187 2e-47
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 187 2e-47
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 187 2e-47
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 184 3e-46
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 182 1e-45
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 181 2e-45
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 177 3e-44
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 176 6e-44
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 176 6e-44
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 176 1e-43
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 174 2e-43
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 171 3e-42
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 171 3e-42
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 163 5e-40
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 163 7e-40
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 157 5e-38
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 154 3e-37
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 1555 bits (4027), Expect = 0.0
Identities = 783/783 (100%), Positives = 783/783 (100%)
Query: 1 MPGKLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKK 60
MPGKLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKK
Sbjct: 1 MPGKLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKK 60
Query: 61 KAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEP 120
KAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEP
Sbjct: 61 KAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEP 120
Query: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQEIP 180
SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQEIP
Sbjct: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQEIP 180
Query: 181 VEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSF 240
VEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSF
Sbjct: 181 VEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSF 240
Query: 241 AIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGG 300
AIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGG
Sbjct: 241 AIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGG 300
Query: 301 QFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVA 360
QFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVA
Sbjct: 301 QFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVA 360
Query: 361 YKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHW 420
YKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHW
Sbjct: 361 YKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHW 420
Query: 421 TQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITL 480
TQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITL
Sbjct: 421 TQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITL 480
Query: 481 KGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICF 540
KGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICF
Sbjct: 481 KGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICF 540
Query: 541 YQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEK 600
YQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEK
Sbjct: 541 YQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEK 600
Query: 601 LIEEKGAVEALAAALAHISGATSVDQRSLINSNVGFVTMILQCSIEMPNISYAWKELKEQ 660
LIEEKGAVEALAAALAHISGATSVDQRSLINSNVGFVTMILQCSIEMPNISYAWKELKEQ
Sbjct: 601 LIEEKGAVEALAAALAHISGATSVDQRSLINSNVGFVTMILQCSIEMPNISYAWKELKEQ 660
Query: 661 LGEEIDSKVKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPREG 720
LGEEIDSKVKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPREG
Sbjct: 661 LGEEIDSKVKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPREG 720
Query: 721 YGGFRGQREGSRGFRGQRDGNRRFRGQREGSRGPRGQRSGGGNKSNRSQNKGQKRSFSKA 780
YGGFRGQREGSRGFRGQRDGNRRFRGQREGSRGPRGQRSGGGNKSNRSQNKGQKRSFSKA
Sbjct: 721 YGGFRGQREGSRGFRGQRDGNRRFRGQREGSRGPRGQRSGGGNKSNRSQNKGQKRSFSKA 780
Query: 781 FGQ 783
FGQ
Sbjct: 781 FGQ 783
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 818 bits (2112), Expect = 0.0
Identities = 435/720 (60%), Positives = 521/720 (72%), Gaps = 34/720 (4%)
Query: 89 SPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKEKEMNGETREKSP 148
S K R+K + + + +K E +++DAPK KK K ++++NG+T E
Sbjct: 20 SESQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPKAKKSKMKEKLNGDTEEGFN 79
Query: 149 KLKNGFPH---------PEPDCNPSEAASEE-----------SNSEIEQEIPVEQKEGAF 188
+L + F P D + E S+ S++++E+ + EQKEGAF
Sbjct: 80 RLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTREQKEGAF 139
Query: 189 SNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKL 248
SNFPISEETIKLLKGRGVT+LFPIQ KTF VY GKDLIAQARTGTGKTFSFAIPLIE+L
Sbjct: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199
Query: 249 HGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNG 308
+ K+ R+P+VLVLAPTRELANQV+KDF DIT+KLSVACFYGGT Y Q +RNG
Sbjct: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVACFYGGTSYQSQINHIRNG 259
Query: 309 IDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDN 368
IDILVGTPGRIKDH+Q+G+LDL+KL+HVVLDEVDQMLD+GFA+QVE+I+ +YK DSEDN
Sbjct: 260 IDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDN 319
Query: 369 PQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIG 428
PQTLLFSATCP WV+ VAKKYMKS YEQVDL+GK TQK A TVEHLAI+CHW+QR AVIG
Sbjct: 320 PQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIG 379
Query: 429 DVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSF 488
DV++VYSG +GR IIFCETKK E++ N IKQ+AQ LHGDI Q QREITLKGFR GSF
Sbjct: 380 DVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLHGDIAQSQREITLKGFREGSF 439
Query: 489 GVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQ 548
VLVATNVAARGLDIPEVDLVIQSSPP+DVESYIHRSGRTGRAGRTG+CICFYQ +E Q
Sbjct: 440 KVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPRERGQ 499
Query: 549 LVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEKLIEEKGAV 608
L VEQKAGI FKR+GVPS +++K+ S DAIR L SV A+ F+ SA++LIEEKGAV
Sbjct: 500 LRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYAAVDFFRPSAQRLIEEKGAV 559
Query: 609 EALAAALAHISGATSVDQRSLINSNVGFVTMILQCSIEMPNISYAWKELKEQLGEEIDSK 668
+ALAAALAHISGA+S + RSLI S+ GFVTM L+ E+ ++S AWKEL +L S+
Sbjct: 560 DALAAALAHISGASSFEPRSLITSDKGFVTMTLESLEEIQDVSCAWKELNRKLSSNAVSQ 619
Query: 669 VKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPREG-------- 720
+ M LKG +GVCFDVPT +Q +WHDS W LSV + PE+E +G
Sbjct: 620 ITRMCLLKGNMGVCFDVPTTESERLQAEWHDS-DWILSVPAKLPEIEEYYDGNTSSNSRQ 678
Query: 721 YGGFRGQREGSRGFRGQRDGNRRFRGQREGSRGPRGQRSGGGNKS---NRSQNKGQKRSF 777
G+ R G G G R G R R R+GSR G R G +S NRS++ G KRSF
Sbjct: 679 RSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRS--GSRQDGRRRSGNRNRSRSGGHKRSF 736
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 206 bits (523), Expect = 9e-53
Identities = 150/452 (33%), Positives = 232/452 (51%), Gaps = 33/452 (7%)
Query: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ--- 177
+EE I K E E + + PK+ P P P+ S A ++ ++
Sbjct: 215 NEEVITGSGKNSWKSEAEGGESSDTQGPKVTY-IPPPPPEDEDSIFAHYQTGINFDKYDT 273
Query: 178 ---EIPVEQKEGAFSNFP---ISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQAR 231
E+ A F + + + G T L P+Q + + +G+DL+A A+
Sbjct: 274 ILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQ 333
Query: 232 TGTGKTFSFAIPLIEKL--HGELQDR-KRGRAPQVLVLAPTRELANQV---SKDFSDITK 285
TG+GKT +F +P++ + G R K + P+ +++APTREL NQ+ ++ FS T
Sbjct: 334 TGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC 393
Query: 286 KLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQML 345
+V YGGT G ++ G +IL TPGR+ D I K+ L ++K++VLDE D+ML
Sbjct: 394 VRAVV-IYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
Query: 346 DMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTY-----EQVDLI 400
DMGF ++++++S S++ QTL+FSAT P + +A +++KS Y QV
Sbjct: 453 DMGFGPEMKKLISCP-GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511
Query: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAI 460
+ Q+T + V + + + IGD RT++F ETKK+A ++
Sbjct: 512 CRDVQQTVLQVGQFSKREKLVEILRNIGDE---------RTMVFVETKKKADFIATFLCQ 562
Query: 461 KQ-DAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVE 519
++ S+HGD Q++RE L FR G VLVAT+VAARGLDI V VI P ++
Sbjct: 563 EKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTID 622
Query: 520 SYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQ 551
Y+HR GRTGR G TG I F+ + + L Q
Sbjct: 623 EYVHRIGRTGRCGNTGRAISFFDLESDNHLAQ 654
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 206 bits (523), Expect = 9e-53
Identities = 150/452 (33%), Positives = 232/452 (51%), Gaps = 33/452 (7%)
Query: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ--- 177
+EE I K E E + + PK+ P P P+ S A ++ ++
Sbjct: 215 NEEVITGSGKNSWKSEAEGGESSDTQGPKVTY-IPPPPPEDEDSIFAHYQTGINFDKYDT 273
Query: 178 ---EIPVEQKEGAFSNFP---ISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQAR 231
E+ A F + + + G T L P+Q + + +G+DL+A A+
Sbjct: 274 ILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQ 333
Query: 232 TGTGKTFSFAIPLIEKL--HGELQDR-KRGRAPQVLVLAPTRELANQV---SKDFSDITK 285
TG+GKT +F +P++ + G R K + P+ +++APTREL NQ+ ++ FS T
Sbjct: 334 TGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC 393
Query: 286 KLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQML 345
+V YGGT G ++ G +IL TPGR+ D I K+ L ++K++VLDE D+ML
Sbjct: 394 VRAVV-IYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
Query: 346 DMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTY-----EQVDLI 400
DMGF ++++++S S++ QTL+FSAT P + +A +++KS Y QV
Sbjct: 453 DMGFGPEMKKLISCP-GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511
Query: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAI 460
+ Q+T + V + + + IGD RT++F ETKK+A ++
Sbjct: 512 CRDVQQTVLQVGQFSKREKLVEILRNIGDE---------RTMVFVETKKKADFIATFLCQ 562
Query: 461 KQ-DAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVE 519
++ S+HGD Q++RE L FR G VLVAT+VAARGLDI V VI P ++
Sbjct: 563 EKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTID 622
Query: 520 SYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQ 551
Y+HR GRTGR G TG I F+ + + L Q
Sbjct: 623 EYVHRIGRTGRCGNTGRAISFFDLESDNHLAQ 654
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 206 bits (523), Expect = 9e-53
Identities = 150/452 (33%), Positives = 232/452 (51%), Gaps = 33/452 (7%)
Query: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ--- 177
+EE I K E E + + PK+ P P P+ S A ++ ++
Sbjct: 181 NEEVITGSGKNSWKSEAEGGESSDTQGPKVTY-IPPPPPEDEDSIFAHYQTGINFDKYDT 239
Query: 178 ---EIPVEQKEGAFSNFP---ISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQAR 231
E+ A F + + + G T L P+Q + + +G+DL+A A+
Sbjct: 240 ILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQ 299
Query: 232 TGTGKTFSFAIPLIEKL--HGELQDR-KRGRAPQVLVLAPTRELANQV---SKDFSDITK 285
TG+GKT +F +P++ + G R K + P+ +++APTREL NQ+ ++ FS T
Sbjct: 300 TGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC 359
Query: 286 KLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQML 345
+V YGGT G ++ G +IL TPGR+ D I K+ L ++K++VLDE D+ML
Sbjct: 360 VRAVV-IYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 418
Query: 346 DMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTY-----EQVDLI 400
DMGF ++++++S S++ QTL+FSAT P + +A +++KS Y QV
Sbjct: 419 DMGFGPEMKKLISCP-GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 477
Query: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAI 460
+ Q+T + V + + + IGD RT++F ETKK+A ++
Sbjct: 478 CRDVQQTVLQVGQFSKREKLVEILRNIGDE---------RTMVFVETKKKADFIATFLCQ 528
Query: 461 KQ-DAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVE 519
++ S+HGD Q++RE L FR G VLVAT+VAARGLDI V VI P ++
Sbjct: 529 EKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTID 588
Query: 520 SYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQ 551
Y+HR GRTGR G TG I F+ + + L Q
Sbjct: 589 EYVHRIGRTGRCGNTGRAISFFDLESDNHLAQ 620
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 204 bits (518), Expect = 3e-52
Identities = 126/376 (33%), Positives = 211/376 (56%), Gaps = 19/376 (5%)
Query: 189 SNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKL 248
+NFP + + +L + T PIQ + F SG+D++ A+TG+GKT ++ +P I +
Sbjct: 176 ANFP--QYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHI 233
Query: 249 HGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMR 306
+ + +RG P LVLAPTRELA QV + D K +L C YGG P G Q +
Sbjct: 234 NHQPY-LERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
Query: 307 NGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSE 366
G++I + TPGR+ D +++GK +L + ++VLDE D+MLDMGF Q+ +I+
Sbjct: 293 RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD-----QIR 347
Query: 367 DNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAV 426
+ QTL++SAT P V +A+ +++ Y Q+++ + ++ + + + +
Sbjct: 348 PDRQTLMWSATWPKEVRQLAEDFLRD-YTQINVGNLELSANHNILQIVDVCMESEKDHKL 406
Query: 427 IGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQD---AQSLHGDIPQKQREITLKGF 483
I + + + + +TIIF ETK+ +L++ +++D A +HGD Q +R+ L F
Sbjct: 407 IQLMEEIMAEKENKTIIFVETKRRCDDLTRR--MRRDGWPAMCIHGDKSQPERDWVLNEF 464
Query: 484 RNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFY-- 541
R+G +L+AT+VA+RGLD+ +V VI P E Y+HR GRT R+ G F+
Sbjct: 465 RSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTP 524
Query: 542 -QHKEEYQLVQVEQKA 556
K+ +L++V ++A
Sbjct: 525 GNLKQARELIKVLEEA 540
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 204 bits (518), Expect = 3e-52
Identities = 126/376 (33%), Positives = 211/376 (56%), Gaps = 19/376 (5%)
Query: 189 SNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKL 248
+NFP + + +L + T PIQ + F SG+D++ A+TG+GKT ++ +P I +
Sbjct: 176 ANFP--QYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHI 233
Query: 249 HGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMR 306
+ + +RG P LVLAPTRELA QV + D K +L C YGG P G Q +
Sbjct: 234 NHQPY-LERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
Query: 307 NGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSE 366
G++I + TPGR+ D +++GK +L + ++VLDE D+MLDMGF Q+ +I+
Sbjct: 293 RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD-----QIR 347
Query: 367 DNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAV 426
+ QTL++SAT P V +A+ +++ Y Q+++ + ++ + + + +
Sbjct: 348 PDRQTLMWSATWPKEVRQLAEDFLRD-YTQINVGNLELSANHNILQIVDVCMESEKDHKL 406
Query: 427 IGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQD---AQSLHGDIPQKQREITLKGF 483
I + + + + +TIIF ETK+ +L++ +++D A +HGD Q +R+ L F
Sbjct: 407 IQLMEEIMAEKENKTIIFVETKRRCDDLTRR--MRRDGWPAMCIHGDKSQPERDWVLNEF 464
Query: 484 RNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFY-- 541
R+G +L+AT+VA+RGLD+ +V VI P E Y+HR GRT R+ G F+
Sbjct: 465 RSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTP 524
Query: 542 -QHKEEYQLVQVEQKA 556
K+ +L++V ++A
Sbjct: 525 GNLKQARELIKVLEEA 540
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 203 bits (517), Expect = 4e-52
Identities = 138/433 (31%), Positives = 227/433 (52%), Gaps = 29/433 (6%)
Query: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ--- 177
S ++ P K +KK+ + ++ PK + F PD A E+ ++
Sbjct: 30 SGKKFGNPGEKLVKKKWNL-----DELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITV 84
Query: 178 ---EIPVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGT 234
P +NFP + + ++ + T IQA+ + SG D++ A+TG+
Sbjct: 85 RGHNCPKPVLNFYEANFPAN--VMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGS 142
Query: 235 GKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACF 292
GKT S+ +P I ++ + +RG P LVLAPTRELA QV + ++ + +L C
Sbjct: 143 GKTLSYLLPAIVHINHQ-PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCI 201
Query: 293 YGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQ 352
YGG P G Q + G++I + TPGR+ D ++ GK +L + ++VLDE D+MLDMGF Q
Sbjct: 202 YGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQ 261
Query: 353 VEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVE 412
+ +I+ + QTL++SAT P V +A+ ++K Y ++ IG +
Sbjct: 262 IRKIVD-----QIRPDRQTLMWSATWPKEVRQLAEDFLKD-YIHIN-IGALELSANHNIL 314
Query: 413 HLAIKCHWTQR-AAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQD---AQSLH 468
+ CH ++ +I + + S + +TI+F ETK+ EL++ +++D A +H
Sbjct: 315 QIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK--MRRDGWPAMGIH 372
Query: 469 GDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRT 528
GD Q++R+ L F++G +L+AT+VA+RGLD+ +V VI P E YIHR GRT
Sbjct: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
Query: 529 GRAGRTGVCICFY 541
R+ +TG F+
Sbjct: 433 ARSTKTGTAYTFF 445
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 198 bits (504), Expect = 1e-50
Identities = 166/578 (28%), Positives = 274/578 (47%), Gaps = 65/578 (11%)
Query: 18 KKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKA 77
K E +RK+ E EK + + K E E + + KQ KK + + D ++
Sbjct: 155 KLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAE 214
Query: 78 KKKEEPSQNDISPKTKSLRKKKEPIEK---------------------KVVSS-KTKKVT 115
K+ E ++ P + + KE ++K KVV+ TKK
Sbjct: 215 KEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAV 274
Query: 116 KNEEPSEEEI---DAPKPKKMKKEKEMNGET-----REKSPKLKNGFPHPEPDCNP---- 163
+ + + E+ D + +E+E++ +T + K KL H + + P
Sbjct: 275 VDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKN 334
Query: 164 --------SEAASEESNS-EIEQEIPVEQKEG------AFSNFPISEETIKLLKGRGVTF 208
++ + EE N +E E + +G ++ IS + + LK G
Sbjct: 335 FYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEK 394
Query: 209 LFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAP 268
PIQ + + SG+DLI A+TG+GKT +F +P+ + + + + G P +++ P
Sbjct: 395 PTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ-RSLEEGEGPIAVIMTP 453
Query: 269 TRELANQVSKDFSDITKKLS--VACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHI--Q 324
TRELA Q++K+ +K L V C YGGT Q ++ G +I+V TPGR+ D +
Sbjct: 454 TRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAAN 513
Query: 325 NGKL-DLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVF 383
+G++ +L ++ +VVLDE D+M DMGF QV I+ + + QT++FSAT P +
Sbjct: 514 SGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVD-----NVRPDRQTVMFSATFPRAME 568
Query: 384 NVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTII 443
+A++ + E V + G+ VE I ++ + +++ Y G II
Sbjct: 569 ALARRILSKPIE-VQVGGRSV--VCSDVEQQVIVIEEEKKFLKLLELLGHYQ-ESGSVII 624
Query: 444 FCETKKEAQELSQN-SAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLD 502
F + ++ A L ++ SLHG I Q R+ + F+NG+ +LVAT+VAARGLD
Sbjct: 625 FVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLD 684
Query: 503 IPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICF 540
+ + LV+ S P E Y+HR+GRTGRAG G F
Sbjct: 685 VKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTF 722
Score = 37.4 bits (85), Expect = 0.054
Identities = 34/177 (19%), Positives = 77/177 (43%), Gaps = 5/177 (2%)
Query: 4 KLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAE 63
+LR E D + ++ + + + + + ++ + + +++ K+K +
Sbjct: 67 RLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS-KEKTD 125
Query: 64 PSEVDMNSPKSK--KAKKKEEPSQN-DISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEP 120
E K K K +KE+ + N D + + +RK+KE +EK + KK +N
Sbjct: 126 GGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQR-KKAMENIGE 184
Query: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ 177
++EI+ K K ++ + + + + K G + +P +A EE E+++
Sbjct: 185 LKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKK 241
Score = 35.0 bits (79), Expect = 0.27
Identities = 31/171 (18%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 24 RKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAK----- 78
R ++ ++++ + +S + + E + ++ + ++ +SP +K K
Sbjct: 59 RSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRS 118
Query: 79 KKEEPSQNDISPKTKSLRK--KKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKE 136
+ +E + S K K K K++ EK + K+ + +E ++ + ++ KK
Sbjct: 119 RSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKA 178
Query: 137 KEMNGETREKSPKLKNG-----FPHPEPDCNPSEAASEESNSEIEQEIPVE 182
E GE +++ ++K G + + +P+EA E + E E+ P++
Sbjct: 179 MENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLD 229
Score = 33.9 bits (76), Expect = 0.60
Identities = 17/48 (35%), Positives = 26/48 (54%)
Query: 728 REGSRGFRGQRDGNRRFRGQREGSRGPRGQRSGGGNKSNRSQNKGQKR 775
RE R +R +R R R SRG R + S GNKS +++N+ + +
Sbjct: 74 RERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 198 bits (503), Expect = 2e-50
Identities = 132/362 (36%), Positives = 195/362 (53%), Gaps = 25/362 (6%)
Query: 185 EGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPL 244
+ AF +P E ++ +K G PIQ++ + V G DLI A+TGTGKT + +P
Sbjct: 244 DDAFQCYP---EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPG 300
Query: 245 IEKLHGELQDRKRGRA--PQVLVLAPTRELANQVSKDFSDITKK-LSVACFYGGTPYGGQ 301
+H LQ +G+ P +LVL PTRELA QV + + K L C YGG Q
Sbjct: 301 F--IHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQ 358
Query: 302 FERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAY 361
E ++ G+DI++ TPGR+ D + ++L + ++VLDE D+MLDMGF Q+ +IL
Sbjct: 359 IEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILL--- 415
Query: 362 KKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTY----EQVDLIGKKTQKTAITVEHLAIK 417
D + QT++ SAT PH V +A+ Y+K +DL+ + K I V K
Sbjct: 416 --DVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEK 473
Query: 418 CHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQR 476
W+ + + + I+F K A LS + + +SLHGD Q+ R
Sbjct: 474 --WSHMQTFLQSM-----SSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDR 526
Query: 477 EITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGV 536
E L+ F+ G +L+AT++A+RGLD+ +V V P+++E Y+HR GRTGRAGRTGV
Sbjct: 527 EKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGV 586
Query: 537 CI 538
I
Sbjct: 587 SI 588
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 194 bits (493), Expect = 3e-49
Identities = 126/391 (32%), Positives = 208/391 (53%), Gaps = 21/391 (5%)
Query: 169 EESNSEIEQEIPVE-QKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLI 227
EE +++E E E F + E+ ++ + G IQ + + G+D+I
Sbjct: 20 EEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVI 79
Query: 228 AQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKL 287
AQ+++GTGKT +F+I +++ L ++ R Q L+LAPTRELA Q+ K + +
Sbjct: 80 AQSQSGTGKTATFSISVLQCLDIQV------RETQALILAPTRELAVQIQKGLLALGDYM 133
Query: 288 SVACF--YGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQML 345
+V C GGT G ++ G ++ GTPGR+ D I+ L +K +VLDE D+ML
Sbjct: 134 NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML 193
Query: 346 DMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQ 405
+ GF +Q+ ++ Q +L SAT PH + + K+M + + ++ K+ +
Sbjct: 194 NKGFKEQIYDVYRYL-----PPATQVVLISATLPHEILEMTNKFMT---DPIRILVKRDE 245
Query: 406 KTAITVEHLAIKCHWTQ-RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-D 463
T ++ + + + + D+ + Q +IFC TK++ L++
Sbjct: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA--VIFCNTKRKVDWLTEKMREANFT 303
Query: 464 AQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIH 523
S+HGD+PQK+RE +K FR+G+ VL++T+V ARGLD+P+V L+I P + E YIH
Sbjct: 304 VSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIH 363
Query: 524 RSGRTGRAGRTGVCICFYQHKEEYQLVQVEQ 554
R GR+GR GR GV I F ++ + L +EQ
Sbjct: 364 RIGRSGRYGRKGVAINFVKNDDIRILRDIEQ 394
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 189 bits (481), Expect = 7e-48
Identities = 155/493 (31%), Positives = 241/493 (48%), Gaps = 35/493 (7%)
Query: 60 KKAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKK--VTKN 117
+ + SE M S K KK+K+K P +S ++ KV S K +T
Sbjct: 39 QNGDVSEETMGSRKVKKSKQK--PMNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNG 96
Query: 118 EEPSEEEIDAPKPKKMKKEKEMN-GETREKSPKLKNGFPHPEPDCNPSEAASEE----SN 172
E + K KK KK K +N E K K +N E ++ N
Sbjct: 97 EAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTKETENNVEKPDN 156
Query: 173 SEIEQEIPVEQK--EGAFSNFP-------ISEETIKLLKGRGVTFLFPIQAKTFHHVYSG 223
E E E+P GAF + ++E T+K +K G T + IQ K+ + G
Sbjct: 157 DEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEG 216
Query: 224 KDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDI 283
+DL+A A+TG+GKT +F IP +E L +L+ R VL+L+PTRELA Q ++
Sbjct: 217 RDLLAAAKTGSGKTLAFLIPAVE-LIVKLRFMPRN-GTGVLILSPTRELAMQTFGVLKEL 274
Query: 284 TKKL--SVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTK-LKHVVLDE 340
+ GG+ + +++ NGI+I+V TPGR+ DH+QN + K L+ +V+DE
Sbjct: 275 MTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDE 334
Query: 341 VDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLI 400
D++LD+GF +++++I+ + + QT+LFSAT V ++A+ +K V +
Sbjct: 335 ADRILDVGFEEELKQIIKLLPTRR-----QTMLFSATQTRKVEDLARISLKKEPLYVGVD 389
Query: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIF---CETKKEAQELSQN 457
K T +E + C +R ++ ++ + + ++F C + K EL
Sbjct: 390 DDKANATVDGLEQGYVVCPSEKRFLLLFTFLK--KNRKKKLMVFFSSCMSVKYHYELL-- 445
Query: 458 SAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKD 517
+ I ++HG Q +R T F N G L+ T+VAARGLDIPEVD ++Q PP D
Sbjct: 446 NYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDD 505
Query: 518 VESYIHRSGRTGR 530
+ YIHR GRT R
Sbjct: 506 PKEYIHRVGRTAR 518
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 188 bits (477), Expect = 2e-47
Identities = 140/447 (31%), Positives = 214/447 (47%), Gaps = 47/447 (10%)
Query: 118 EEPSEEEIDAPKPKKMKKEKEM--NGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEI 175
++ E++ P P + E+E+ G T G + D P EA I
Sbjct: 129 DKSDEDDWSKPLPPSERLEQELFSGGNT---------GINFEKYDDIPVEATGNNCPPHI 179
Query: 176 EQEIPVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTG 235
E VE E N ++ T P+Q + +DL+A A+TG+G
Sbjct: 180 ESFSDVEMGEIIMGNIELTRYTRPT----------PVQKHAIPIIKEKRDLMACAQTGSG 229
Query: 236 KTFSFAIPLIEKLHGE---------LQDRKRGRAPQV---LVLAPTRELANQVSKDFSDI 283
KT +F +P++ +++ + ++ + GR Q LVLAPTRELA Q+ ++
Sbjct: 230 KTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF 289
Query: 284 TKKLSV--ACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEV 341
+ + V YGG G Q + G +LV TPGR+ D ++ GK+ L K++VLDE
Sbjct: 290 SYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEA 349
Query: 342 DQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIG 401
D+MLDMGF Q+ I+ + T++FSAT P + +A+ ++ + I
Sbjct: 350 DRMLDMGFEPQIRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIF 402
Query: 402 KKTQKTAITVEHLAIKCHWTQRA---AVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNS 458
+ T E++ K W + + + + D++ +G T++F ETKK A L
Sbjct: 403 LAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNA-TGKDSLTLVFVETKKGADSLEDFL 461
Query: 459 AIKQDA-QSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKD 517
+ A S+HGD Q+ RE L FR+G +LVAT VAARGLDI V VI P D
Sbjct: 462 YHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSD 521
Query: 518 VESYIHRSGRTGRAGRTGVCICFYQHK 544
+E Y+HR GRTGR G G+ F+ +
Sbjct: 522 IEEYVHRIGRTGRVGNLGLATSFFNER 548
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 187 bits (476), Expect = 2e-47
Identities = 118/368 (32%), Positives = 195/368 (52%), Gaps = 13/368 (3%)
Query: 180 PVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFS 239
P + + AF +P + +K + G+ PIQ++ + + G DLI A+TGTGKT S
Sbjct: 219 PTCRFKDAFQQYP---DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLS 275
Query: 240 FAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKK-LSVACFYGGTPY 298
+ +P L + R++ P +LVL PTRELA V + S + K L C YGG
Sbjct: 276 YLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGLKSICIYGGRNR 335
Query: 299 GGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILS 358
GQ E + G+DI++ TPGR+ D N ++L + ++V+DE D+MLDM F Q+ +IL
Sbjct: 336 NGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL- 394
Query: 359 VAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKC 418
D + QT++ SAT P V +A Y+K + +G TV+ I
Sbjct: 395 ----LDVRPDRQTVMTSATWPDTVRQLALSYLKD--PMIVYVGNLNLVAVNTVKQNIIVT 448
Query: 419 HWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQRE 477
++ A+ + + S + + I+F K A +LS + I+ A+SLHG+ Q +E
Sbjct: 449 TEKEKRALTQEFVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQE 507
Query: 478 ITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVC 537
++ F++G+ +L+ T++ +RGLD+ +V V P++++ Y+HR G GR G+TG
Sbjct: 508 RAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTS 567
Query: 538 ICFYQHKE 545
+ ++
Sbjct: 568 VTLITQRD 575
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 187 bits (476), Expect = 2e-47
Identities = 143/440 (32%), Positives = 218/440 (49%), Gaps = 44/440 (10%)
Query: 138 EMNGETREKSPKLKNGFPHPEPDCNPSEAASEES--------NSEIEQEIPVEQKEGA-- 187
E +G +R +++ + P P PSE +E N E +IPVE
Sbjct: 118 ERSGHSRWCDKSVEDDWSKPLP---PSERLEQELFSGGNTGINFEKYDDIPVEATGSNCP 174
Query: 188 -----FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAI 242
FS+ + E + ++ T P+Q + +DL+A A+TG+GKT +F +
Sbjct: 175 PHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLL 234
Query: 243 PLIEKLH----GEL-----QDRKRGRAPQV---LVLAPTRELANQVSKDFSDITKKLSV- 289
P++ +++ GE ++ + GR Q LVLAPTRELA Q+ ++ + + V
Sbjct: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVR 294
Query: 290 -ACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMG 348
YGG G Q + G +LV TPGR+ D ++ GK+ L K++VLDE D+MLDMG
Sbjct: 295 PCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMG 354
Query: 349 FADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTA 408
F Q+ I+ + T++FSAT P + +A+ ++ + I +
Sbjct: 355 FEPQIRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVG 407
Query: 409 ITVEHLAIKCHWTQ---RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDA- 464
T E++ K W + + + + D++ +G T++F ETKK A L + A
Sbjct: 408 STSENITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466
Query: 465 QSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHR 524
S+HGD Q+ RE L FR+G +LVAT VAARGLDI V VI P D+E Y+HR
Sbjct: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526
Query: 525 SGRTGRAGRTGVCICFYQHK 544
GRTGR G G+ F+ K
Sbjct: 527 IGRTGRVGNLGLATSFFNEK 546
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 187 bits (476), Expect = 2e-47
Identities = 143/440 (32%), Positives = 218/440 (49%), Gaps = 44/440 (10%)
Query: 138 EMNGETREKSPKLKNGFPHPEPDCNPSEAASEES--------NSEIEQEIPVEQKEGA-- 187
E +G +R +++ + P P PSE +E N E +IPVE
Sbjct: 118 ERSGHSRWCDKSVEDDWSKPLP---PSERLEQELFSGGNTGINFEKYDDIPVEATGSNCP 174
Query: 188 -----FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAI 242
FS+ + E + ++ T P+Q + +DL+A A+TG+GKT +F +
Sbjct: 175 PHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLL 234
Query: 243 PLIEKLH----GEL-----QDRKRGRAPQV---LVLAPTRELANQVSKDFSDITKKLSV- 289
P++ +++ GE ++ + GR Q LVLAPTRELA Q+ ++ + + V
Sbjct: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVR 294
Query: 290 -ACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMG 348
YGG G Q + G +LV TPGR+ D ++ GK+ L K++VLDE D+MLDMG
Sbjct: 295 PCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMG 354
Query: 349 FADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTA 408
F Q+ I+ + T++FSAT P + +A+ ++ + I +
Sbjct: 355 FEPQIRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVG 407
Query: 409 ITVEHLAIKCHWTQ---RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDA- 464
T E++ K W + + + + D++ +G T++F ETKK A L + A
Sbjct: 408 STSENITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466
Query: 465 QSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHR 524
S+HGD Q+ RE L FR+G +LVAT VAARGLDI V VI P D+E Y+HR
Sbjct: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526
Query: 525 SGRTGRAGRTGVCICFYQHK 544
GRTGR G G+ F+ K
Sbjct: 527 IGRTGRVGNLGLATSFFNEK 546
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 184 bits (467), Expect = 3e-46
Identities = 121/372 (32%), Positives = 198/372 (53%), Gaps = 21/372 (5%)
Query: 187 AFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIE 246
+F + +SE ++ + G IQ + G D+IAQA++GTGKT +FAI +++
Sbjct: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92
Query: 247 KLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACF--YGGTPYGGQFER 304
++ +L +A Q LVLAPTRELA Q+ K + + +C GGT + ++
Sbjct: 93 QIELDL------KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQK 146
Query: 305 MR-NGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKK 363
++ I+VGTPGR+ D + L +K VLDE D+ML GF DQ+ +I +
Sbjct: 147 LQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF-----Q 201
Query: 364 DSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQ- 422
N Q +L SAT P V V KK+M+ + + ++ KK + T + I +
Sbjct: 202 KLNSNTQVVLLSATMPSDVLEVTKKFMR---DPIRILVKKEELTLEGIRQFYINVEREEW 258
Query: 423 RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQREITLK 481
+ + D+ + Q +IF T+++ L++ + ++HGD+ QK+R++ ++
Sbjct: 259 KLDTLCDLYETLTITQA--VIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316
Query: 482 GFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFY 541
FR+GS VL+ T++ ARG+D+ +V LVI P + E+YIHR GR GR GR GV I
Sbjct: 317 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376
Query: 542 QHKEEYQLVQVE 553
+++ L +E
Sbjct: 377 TEEDKRTLRDIE 388
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 182 bits (462), Expect = 1e-45
Identities = 171/619 (27%), Positives = 282/619 (45%), Gaps = 77/619 (12%)
Query: 28 EEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAKKKEEPSQND 87
E+ E +P+SD +E EEE ++ K + D N K+
Sbjct: 44 EDDEVPVEPESDSGDE---EEEGPIVLGRRQKALGKNRSADFNPDFVFTEKEGTYDGSWA 100
Query: 88 ISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKEKEMNGETREKS 147
++ L+KK+ + K +KV K + ++E + K +K K+ KE E +E+
Sbjct: 101 LADVMSQLKKKRAAT---TLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKE-GSEPKEQE 156
Query: 148 PKLKNGFPHPEPDCNPSEAASEESNSEIEQEI------PVEQKEG--------------- 186
+N E + + ++ +S + N + + ++K+G
Sbjct: 157 DLQENDEEGSEDEASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDE 216
Query: 187 --AFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPL 244
+F + +S +K + G PIQ GKD+ A A TGTGKT +FA+P+
Sbjct: 217 NLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPV 276
Query: 245 IEKLHGELQDRKRGRAPQVLVLAPTRELANQVSK------DFSDITKKLSVACFYGGTPY 298
+E+L + ++ +VLVL PTREL QV F +IT L+V GG
Sbjct: 277 LERL---IYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAV----GGLDV 329
Query: 299 GGQFERMRNGIDILVGTPGRIKDHIQN-GKLDLTKLKHVVLDEVDQMLDMGFADQVEEIL 357
Q +R DIL+ TPGR+ DH+ N L+ ++ ++LDE D+MLD F +Q++EI+
Sbjct: 330 KSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEII 389
Query: 358 SVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIK 417
+ + QT+LFSAT V ++A +K+ ++ + + E + I+
Sbjct: 390 RMC-----SHHRQTMLFSATMTDEVKDLASVSLKNPV-RIFVNSNTDVAPFLRQEFIRIR 443
Query: 418 CHWT-QRAAVIGDVI-RVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQK 474
+ R A++ ++ R ++ H ++F +TKK+A + + LHG++ Q
Sbjct: 444 PNREGDREAIVAALLTRTFTDH---VMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQT 500
Query: 475 QREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRT 534
QR L+ F++ +LVAT+VAARGLDI V VI + P ++ Y+HR GRT RAGR
Sbjct: 501 QRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRA 560
Query: 535 GVCICFYQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHF 594
G + E L ++ + A KA K I +P I F
Sbjct: 561 GRSVSLVGEDERKMLKEIVKAA----------------KAPVKARI-----LPQDVILKF 599
Query: 595 KQSAEKLIEEKGAVEALAA 613
+ EK+ ++ AV L A
Sbjct: 600 RDKIEKMEKDVYAVLQLEA 618
Score = 31.2 bits (69), Expect = 3.9
Identities = 29/144 (20%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 23 LRKQTEEKEKKEKPKSDKT---------EEIAEEEETVFPKAKQVKKKAEPSEVDMNSPK 73
L+ + EEKE ++ T E + +E E + + K+ +KK + ++
Sbjct: 614 LQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKIAKALQEFDL 673
Query: 74 SKKAKKKEEPSQNDISPK---TKSLRKKKEPIEKKVVSSKTKKVTKNEE-----PSEEEI 125
+ + KKK + D K T R + E ++ ++ + + K + + P EE +
Sbjct: 674 ALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAERLAKRNRRAKRARAMPEEEPV 733
Query: 126 DAPKPKKMKKEKEMNGETREKSPK 149
P K+ + +K + E + K
Sbjct: 734 RGPAKKQKQGKKSVFDEELTNTSK 757
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 181 bits (459), Expect = 2e-45
Identities = 122/371 (32%), Positives = 196/371 (52%), Gaps = 21/371 (5%)
Query: 188 FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEK 247
F + + E ++ + G IQ + G D+IAQA++GTGKT +FAI ++++
Sbjct: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
Query: 248 LHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACF--YGGTPYGGQFERM 305
L E ++ Q LVLAPTRELA Q+ K + + C GGT + +++
Sbjct: 95 LEIEFKET------QALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKL 148
Query: 306 R-NGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKD 364
+ I+VGTPGR+ D + L +K VLDE D+ML GF DQ+ EI +
Sbjct: 149 QAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIF-----QK 203
Query: 365 SEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQ-R 423
+ Q +L SAT P V V KK+M+ + + ++ KK + T ++ I + +
Sbjct: 204 LNTSIQVVLLSATMPTDVLEVTKKFMR---DPIRILVKKEELTLEGIKQFYINVEREEWK 260
Query: 424 AAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQREITLKG 482
+ D+ + Q +IF T+++ L++ + +LHGD+ QK+R++ ++
Sbjct: 261 LDTLCDLYETLTITQA--VIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMRE 318
Query: 483 FRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQ 542
FR+GS VL+ T++ ARG+D+ +V LVI P + E+YIHR GR GR GR GV I F
Sbjct: 319 FRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVT 378
Query: 543 HKEEYQLVQVE 553
+++ L +E
Sbjct: 379 EEDKRILRDIE 389
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 177 bits (449), Expect = 3e-44
Identities = 154/559 (27%), Positives = 256/559 (45%), Gaps = 45/559 (8%)
Query: 44 IAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAKKKEEP--SQNDISPKTKSLRKKKEP 101
+ + + + K Q ++K E +S + + + P Q+++S + + KE
Sbjct: 39 LRQRRQLLLQKLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQH-QHLKEK 97
Query: 102 IEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDC 161
E + S+K K++ + E+ E + + + KEM P +K + P
Sbjct: 98 AEARKESAKEKQLKEEEKILESVAEG---RALMSVKEMAKGITYDDP-IKTSWTPPRYVL 153
Query: 162 NPSEAASEESNSEIE-----QEIPVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKT 216
+ SE E + IP K FP + ++ LK +G+ PIQ +
Sbjct: 154 SMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAA--ILRGLKKKGIHHPTPIQIQG 211
Query: 217 FHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKR-----GRAPQVLVLAPTRE 271
+ SG+D+I A TG+GKT F +P+I L+ KR P L++ P+RE
Sbjct: 212 IPTILSGRDMIGIAFTGSGKTLVFTLPVIMFC---LEQEKRLPFSKREGPYGLIICPSRE 268
Query: 272 LANQVSKDFS--------DITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHI 323
LA Q D + L A GG Q E +R+G+ ++V TPGR+ D +
Sbjct: 269 LARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLL 328
Query: 324 QNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVF 383
Q + L +++ LDE D+M+DMGF + I S Y K QTLLFSAT P +
Sbjct: 329 QKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFS--YFKGQR---QTLLFSATMPKKIQ 383
Query: 384 NVAKKYM-KSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTI 442
N AK + K V G + VE++ + A + ++ +
Sbjct: 384 NFAKSALVKPVTINVGRAGAASLDVIQEVEYV-------KEEAKMVYLLECLQKTPPPVL 436
Query: 443 IFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGL 501
IF E K + + + +K +A ++HG Q++R ++ FR G VLVAT+VA++GL
Sbjct: 437 IFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGL 496
Query: 502 DIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFK 561
D P + VI P+++E+Y+HR GRTGR+G TG+ F +K + V ++ KA +
Sbjct: 497 DFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFI-NKACDESVLMDLKALLLEA 555
Query: 562 RIGVPSATEIIKASSKDAI 580
+ VP +++ + +
Sbjct: 556 KQKVPPVLQVLHCGDESML 574
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 176 bits (447), Expect = 6e-44
Identities = 151/543 (27%), Positives = 246/543 (45%), Gaps = 72/543 (13%)
Query: 60 KKAEPSEVDM------NSPKSKKAKKKEEPSQNDISPKTKSLRKKKEP-------IEKKV 106
++ + S VD+ NSP ++ K S +D P + + ++ +E+K
Sbjct: 79 EEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKD 138
Query: 107 VSSKTKKVTKNEEPSEEEIDA--------PKPKKMKKEKEMN------GETREKSPKLKN 152
K K +++ E++ +A P +++E+E N G + K+ +
Sbjct: 139 KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIID 198
Query: 153 GFP---HPEPDCNPSEAASEESNSEIEQEIPVE------------------QKEGAFSNF 191
P H E D P E + EI P + + +F++F
Sbjct: 199 PLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHF 258
Query: 192 PISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGE 251
E+ + ++ T PIQ + SG+D+I A+TG+GKT +F P++ + +
Sbjct: 259 GFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ 318
Query: 252 LQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMRNGI 309
++ + G P +++ PTREL Q+ + K L YGG Q + ++ G
Sbjct: 319 -KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGA 377
Query: 310 DILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNP 369
+I+V TPGR+ DH++ +L ++ ++V DE D+M DMGF QV I S +
Sbjct: 378 EIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPDR 432
Query: 370 QTLLFSATCPHWVFNVAKKYMKSTYEQVDL-IGKKTQKTAITVEHL---AIKCHWTQRAA 425
QTLLFSAT + +A+ + V IG+ + VE L K +W R
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
Query: 426 VIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSL---HGDIPQKQREITLKG 482
V G ++F K A+EL+ N +KQ+ +L HGD+ Q +R +
Sbjct: 493 V-------EFTSSGSVLLFVTKKANAEELANN--LKQEGHNLGLLHGDMDQSERNKVISD 543
Query: 483 FRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQ 542
F+ VLVAT+VAARGLDIP + VI +D++++ HR GRTGRAG GV
Sbjct: 544 FKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLT 603
Query: 543 HKE 545
K+
Sbjct: 604 PKD 606
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 176 bits (447), Expect = 6e-44
Identities = 151/543 (27%), Positives = 246/543 (45%), Gaps = 72/543 (13%)
Query: 60 KKAEPSEVDM------NSPKSKKAKKKEEPSQNDISPKTKSLRKKKEP-------IEKKV 106
++ + S VD+ NSP ++ K S +D P + + ++ +E+K
Sbjct: 79 EEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKD 138
Query: 107 VSSKTKKVTKNEEPSEEEIDA--------PKPKKMKKEKEMN------GETREKSPKLKN 152
K K +++ E++ +A P +++E+E N G + K+ +
Sbjct: 139 KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIID 198
Query: 153 GFP---HPEPDCNPSEAASEESNSEIEQEIPVE------------------QKEGAFSNF 191
P H E D P E + EI P + + +F++F
Sbjct: 199 PLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHF 258
Query: 192 PISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGE 251
E+ + ++ T PIQ + SG+D+I A+TG+GKT +F P++ + +
Sbjct: 259 GFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQ 318
Query: 252 LQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMRNGI 309
++ + G P +++ PTREL Q+ + K L YGG Q + ++ G
Sbjct: 319 -KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGA 377
Query: 310 DILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNP 369
+I+V TPGR+ DH++ +L ++ ++V DE D+M DMGF QV I S +
Sbjct: 378 EIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHV-----RPDR 432
Query: 370 QTLLFSATCPHWVFNVAKKYMKSTYEQVDL-IGKKTQKTAITVEHL---AIKCHWTQRAA 425
QTLLFSAT + +A+ + V IG+ + VE L K +W R
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
Query: 426 VIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSL---HGDIPQKQREITLKG 482
V G ++F K A+EL+ N +KQ+ +L HGD+ Q +R +
Sbjct: 493 V-------EFTSSGSVLLFVTKKANAEELANN--LKQEGHNLGLLHGDMDQSERNKVISD 543
Query: 483 FRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQ 542
F+ VLVAT+VAARGLDIP + VI +D++++ HR GRTGRAG GV
Sbjct: 544 FKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLT 603
Query: 543 HKE 545
K+
Sbjct: 604 PKD 606
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 176 bits (445), Expect = 1e-43
Identities = 142/435 (32%), Positives = 217/435 (49%), Gaps = 22/435 (5%)
Query: 128 PKP-KKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQEIPVEQKEG 186
P P + + K+ + + K +L+ PE + N E +I V +
Sbjct: 14 PDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYE---KINVNEIT- 69
Query: 187 AFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIE 246
FS+FP+S++T+K L+ + IQ +T GKD++ A+TG+GKT +F +P++E
Sbjct: 70 RFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLE 129
Query: 247 KLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKK--LSVACFYGGTPYGGQFER 304
L+ G VL+++PTRELA Q + + K S GG + ER
Sbjct: 130 ALYRLQWTSTDGLG--VLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAER 187
Query: 305 MRNGIDILVGTPGRIKDHI-QNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKK 363
+ N I+ILV TPGR+ H+ + T L+ +VLDE D++LDMGFAD + ++ KK
Sbjct: 188 INN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKK 246
Query: 364 DSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQR 423
QTLLFSAT V ++A+ +K+ E V + K T T+E I C Q+
Sbjct: 247 R-----QTLLFSATQTKSVKDLARLSLKNP-EYVWVHEKAKYSTPATLEQNYIVCELQQK 300
Query: 424 AAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQS---LHGDIPQKQREITL 480
+V+ +R S + ++I+F + KE Q L + + S LHG Q +R
Sbjct: 301 ISVLYSFLR--SHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVY 358
Query: 481 KGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICF 540
F VL AT++AARGLD P V+ V+Q P+D +YIHR+GRT R G +
Sbjct: 359 NEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLI 418
Query: 541 YQHKEEYQLVQVEQK 555
E+ + Q+ QK
Sbjct: 419 LLPSEKAMVQQLLQK 433
Score = 31.6 bits (70), Expect = 3.0
Identities = 40/193 (20%), Positives = 83/193 (43%), Gaps = 26/193 (13%)
Query: 12 ESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNS 71
E + ++KG + TE ++ + ++ EE +EEE ++ KA+ S+
Sbjct: 554 EKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEE-----MEEKLAKAKGSQAPSLP 608
Query: 72 PKSKKAKKKEEPSQ----NDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEID- 126
S+ K KE P+Q ++ L+ K+ + + K +K + +EPS+ I
Sbjct: 609 NTSEAQKIKEVPTQFLDRDEEEEDADFLKVKRHNVFG--LDLKDEKTLQKKEPSKSSIKK 666
Query: 127 -----APKPKKMKKEKEMN--------GETREKSPKL-KNGFPHPEPDCNPSEAASEESN 172
A K MK+ ++N GE ++ P++ K+ E D + ++
Sbjct: 667 KMTKVAEAKKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDTGGINLHKAK 726
Query: 173 SEIEQEIPVEQKE 185
+++E +++E
Sbjct: 727 ERLQEEDKFDKEE 739
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 174 bits (442), Expect = 2e-43
Identities = 159/573 (27%), Positives = 269/573 (46%), Gaps = 54/573 (9%)
Query: 21 ETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAKKK 80
ET + EE +K + + DK++E+ +E K+ ++ +N K
Sbjct: 224 ETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRH-----LNDRKFVFEWDA 278
Query: 81 EEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKEKEMN 140
E + D +P K R + + + + ++ K K E+ S D + ++ +EKE
Sbjct: 279 SEDTSIDYNPLYKE-RHQVQLLGRGFIAGIDLKQQKREQ-SRFYGDLMEKRRTLEEKEQE 336
Query: 141 GETREKSPKLKNGFPHPEPDCNPSEAASEESNSE----IEQEIPVEQKEGAFSNFPISE- 195
E R + + K + D + S+ +E ++ + K G N PI
Sbjct: 337 -EARLRKLRKKEAKQRWD-DRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPN-PIRSW 393
Query: 196 -------ETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPL---I 245
++++ G PIQ + +D+I A TG+GKT +F IPL I
Sbjct: 394 KDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWI 453
Query: 246 EKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSV--ACFYGGTPYGGQFE 303
L + + + P ++LAPTRELA Q+ ++ K L + GG Q
Sbjct: 454 TTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGF 513
Query: 304 RMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILS---VA 360
R+R G +I++ TPGR+ D ++N L L++ +VVLDE D+M+DMGF V++IL V+
Sbjct: 514 RLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVS 573
Query: 361 YKK---DSEDNP---------------QTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGK 402
+K D ++P QT++F+AT P V +A+ Y++ V IG
Sbjct: 574 NQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRP--AVVYIGS 631
Query: 403 KTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQN-SAIK 461
+ + + + +R ++ + + G IIF KK L+++ +
Sbjct: 632 AGKPHERVEQKVFLMSESEKRKKLLAILEQ---GFDPPIIIFVNQKKGCDVLAKSLEKMG 688
Query: 462 QDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESY 521
+A +LHG Q+QRE L + G+ +LVAT+VA RG+DI +V +V+ K++E Y
Sbjct: 689 YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDY 748
Query: 522 IHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQ 554
IHR GRTGRAG++GV I F ++ +++Q
Sbjct: 749 IHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQ 781
Score = 38.5 bits (88), Expect = 0.024
Identities = 41/176 (23%), Positives = 75/176 (42%), Gaps = 8/176 (4%)
Query: 6 RSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPS 65
R + S + K E R+ E + KE+ ++ K + +++ K ++ +
Sbjct: 54 RGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRD-RDKDGHRRDKDRKRSSLSPGR 112
Query: 66 EVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEI 125
D S K + +KK EE D PK + L +E + KK + + K +E E
Sbjct: 113 GKDFKSRKDRDSKKDEEDEHGDKKPKAQPL-SLEELLAKKKAEEEAEAKPKFLSKAEREA 171
Query: 126 DAPKPKKMKKE--KEMNGETREKSPKLKN-GFPHPEPDCNPSEAASEESNSEIEQE 178
+A K ++ + E + M E R+K + ++ G E +P E E +E+E
Sbjct: 172 EALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLE---DPQERERRERRERMERE 224
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 171 bits (432), Expect = 3e-42
Identities = 125/407 (30%), Positives = 197/407 (48%), Gaps = 22/407 (5%)
Query: 136 EKEMNGETREKSPKLKNGFPHPE-PDCNPSEAASEESNSEIEQEIPVEQKEGAFSNFPIS 194
E E+ E ++ KL G P P P + ++ + + ++K G F + +S
Sbjct: 45 EFEIQAEDDARARKLGPGRPLPTFPTSECTSDVEPDTREMVRAQNKKKKKSGGFQSMGLS 104
Query: 195 EETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQD 254
K + +G PIQ KT + GKD++A ARTG+GKT F +P+ E+L +
Sbjct: 105 YPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERL----KT 160
Query: 255 RKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMRNGIDIL 312
+ L+L+PTRELA Q K ++ K L A GG QF + DI+
Sbjct: 161 HSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDII 220
Query: 313 VGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTL 372
+ TPGR+ L L +++VV DE D++ +MGFA+Q++EI++ QT+
Sbjct: 221 IATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARL-----PGGHQTV 275
Query: 373 LFSATCPHWVFNVAKKYMKSTYE---QVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGD 429
LFSAT P + A+ + VD + KT+ + K AAV+
Sbjct: 276 LFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTK------AAVLLH 329
Query: 430 VIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQREITLKGFRNGSF 488
++ Q +T++F TK A+ L++ ++ ++ + R+I L F G
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389
Query: 489 GVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTG 535
L+ T++AARGLDIP +D VI S P + ++HR GR RAGR+G
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSG 436
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 171 bits (432), Expect = 3e-42
Identities = 125/407 (30%), Positives = 197/407 (48%), Gaps = 22/407 (5%)
Query: 136 EKEMNGETREKSPKLKNGFPHPE-PDCNPSEAASEESNSEIEQEIPVEQKEGAFSNFPIS 194
E E+ E ++ KL G P P P + ++ + + ++K G F + +S
Sbjct: 45 EFEIQAEDDARARKLGPGRPLPTFPTSECTSDVEPDTREMVRAQNKKKKKSGGFQSMGLS 104
Query: 195 EETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQD 254
K + +G PIQ KT + GKD++A ARTG+GKT F +P+ E+L +
Sbjct: 105 YPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERL----KT 160
Query: 255 RKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMRNGIDIL 312
+ L+L+PTRELA Q K ++ K L A GG QF + DI+
Sbjct: 161 HSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDII 220
Query: 313 VGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTL 372
+ TPGR+ L L +++VV DE D++ +MGFA+Q++EI++ QT+
Sbjct: 221 IATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARL-----PGGHQTV 275
Query: 373 LFSATCPHWVFNVAKKYMKSTYE---QVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGD 429
LFSAT P + A+ + VD + KT+ + K AAV+
Sbjct: 276 LFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTK------AAVLLH 329
Query: 430 VIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQREITLKGFRNGSF 488
++ Q +T++F TK A+ L++ ++ ++ + R+I L F G
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389
Query: 489 GVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTG 535
L+ T++AARGLDIP +D VI S P + ++HR GR RAGR+G
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSG 436
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 163 bits (413), Expect = 5e-40
Identities = 120/390 (30%), Positives = 196/390 (50%), Gaps = 33/390 (8%)
Query: 184 KEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIP 243
K F ++ + E + + G PIQ ++ SG+D++A+A+ GTGK+ ++ IP
Sbjct: 94 KGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIP 153
Query: 244 LIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLS---VACFYGGTPYGG 300
L+E+L D K+ Q +V+ PTRELA QVS+ ++K + V GGT
Sbjct: 154 LLERL-----DLKKDNI-QAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRD 207
Query: 301 QFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVA 360
R+ + + +++ TPGRI D I+ G + ++ +VLDE D++L F +E+I+
Sbjct: 208 DIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTL 267
Query: 361 YKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYE-----QVDLIGKKTQKTAITVEHLA 415
K N Q LL+SAT P V +++ YE ++ L G TQ A E
Sbjct: 268 PK-----NRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGV-TQYYAYVTERQK 321
Query: 416 IKCHWTQRAAVIGDVIRVYSGHQ-GRTIIFCETKKEAQELSQN-SAIKQDAQSLHGDIPQ 473
+ C T ++S Q ++IIFC + + + L++ S + +H + Q
Sbjct: 322 VHCLNT-----------LFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQ 370
Query: 474 KQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGR 533
+ R FRNG LV T++ RG+DI V++VI PK E+Y+HR GR+GR G
Sbjct: 371 EHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGH 430
Query: 534 TGVCICFYQHKEEYQLVQVEQKAGIKFKRI 563
G+ I + + + L +E++ G + K I
Sbjct: 431 LGLAINLITYDDRFNLKSIEEQLGTEIKPI 460
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 163 bits (412), Expect = 7e-40
Identities = 133/405 (32%), Positives = 205/405 (50%), Gaps = 32/405 (7%)
Query: 166 AASEESNSEIEQEIPV--EQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSG 223
AA EE +S E P+ E++ F + +++ + G T IQ + G
Sbjct: 2 AAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQG 61
Query: 224 KDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDI 283
+D+I A TG+GKT +FA+P++ L L+ +R A LVL PTRELA Q+S+ F +
Sbjct: 62 RDIIGLAETGSGKTGAFALPILNAL---LETPQRLFA---LVLTPTRELAFQISEQFEAL 115
Query: 284 TKKLSV--ACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGK-LDLTKLKHVVLDE 340
+ V A GG Q + I++ TPGR+ DH++N K +L LK++V+DE
Sbjct: 116 GSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDE 175
Query: 341 VDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLI 400
D++L+M F +V++IL V + + +T LFSAT V + + +K+ + +
Sbjct: 176 ADRILNMDFETEVDKILKVIPR-----DRKTFLFSATMTKKVQKLQRAALKNPVKCA--V 228
Query: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQ---GRTIIFCETKKEAQE---L 454
K Q TVE L + ++ + D VY ++ +IFC T Q L
Sbjct: 229 SSKYQ----TVEKL--QQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALL 282
Query: 455 SQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSP 514
+N A LHG + Q +R +L F+ + +L+AT+VA+RGLDIP VD+V+
Sbjct: 283 LRNLGFT--AIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDI 340
Query: 515 PKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIK 559
P + YIHR GRT RAGR+G I F + ++E G K
Sbjct: 341 PTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKK 385
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 157 bits (396), Expect = 5e-38
Identities = 140/570 (24%), Positives = 258/570 (45%), Gaps = 50/570 (8%)
Query: 4 KLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAE 63
K++ +A + + + K + K E + +K + + +A E T+ +
Sbjct: 8 KIKRNANDDGKSCVAK---IIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESCPFPS 64
Query: 64 PSE--VDMNSPKSKKAKKKEEPSQNDISPKTKSLR--KKKEPIEKKVVSSKTKKVTKNEE 119
P +++S ++ K PS+ + +K+ R + EPI VV + + ++
Sbjct: 65 PGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPI--CVVCGRYGEYICDKT 122
Query: 120 PSEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEES---NSEIE 176
+ K K + + KE +++ +P+ + PE N S E N + +
Sbjct: 123 DEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADS--EPESPLNASYVYKEHPFILNLQED 180
Query: 177 QEIPVEQKEGA-------------FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSG 223
Q ++Q+ G F + + E LK G PIQ + G
Sbjct: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240
Query: 224 KDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDI 283
+D++A A TG+GKT +F +P+I + E + P L+L PTRELA Q+ + ++
Sbjct: 241 RDILASADTGSGKTAAFLLPVIMRALFE------SKTPSALILTPTRELAIQIERQAKEL 294
Query: 284 TK---KLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDE 340
++ GG P Q R++ + +++ TPGR+ D I+ ++L +K VV+DE
Sbjct: 295 MSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDE 354
Query: 341 VDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLI 400
D ML MGF QV +IL ++ ++ QT+L SAT P + +A + + + V +I
Sbjct: 355 ADTMLKMGFQQQVLDIL-----ENIPNDCQTILVSATIPTSIEQLASQLL---HNPVRII 406
Query: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAI 460
+ V + + + + +++ + ++F + K A LS+ A+
Sbjct: 407 TGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSE--AV 464
Query: 461 KQ----DAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPK 516
++ + S+H + Q +R+ LKG G + V+V+T V RGLD+ V LV+ P
Sbjct: 465 QKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPS 524
Query: 517 DVESYIHRSGRTGRAGRTGVCICFYQHKEE 546
++ Y+H+ GR GR G+ G I F + +
Sbjct: 525 SMDEYVHQIGRVGRLGQNGTAITFINNNSK 554
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 154 bits (389), Expect = 3e-37
Identities = 118/385 (30%), Positives = 195/385 (50%), Gaps = 36/385 (9%)
Query: 185 EGAFSNFPIS--EETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAI 242
EG++ + P+ + + L+ G ++ P+Q+ T KD+ A+A TG+GKT +F I
Sbjct: 6 EGSWESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVI 65
Query: 243 PLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK---KLSVACFYGGTPYG 299
P++E L + K+ + +++ PTRELA Q+ + S TK + S + GG G
Sbjct: 66 PILEILLRREEKLKKSQVGAIII-TPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPG 124
Query: 300 GQFERMRN-GIDILVGTPGRIKDHIQNGK--LDLTK----LKHVVLDEVDQMLDMGFADQ 352
ER + G +I+V TPGR++D + LDL L +VLDE D++LDMGF
Sbjct: 125 EDVERFKQQGGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEAS 184
Query: 353 VEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKS----TYEQVDLIGKKTQKTA 408
+ IL K+ +T LFSAT V N+ + +++ + ++ + QKT
Sbjct: 185 INTILEFLPKQR-----RTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTP 239
Query: 409 ITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCET-------KKEAQELSQNSAIK 461
+E+ + C ++ + +R + Q + ++F T K + L + I
Sbjct: 240 SRLENYYMVCKADEKFNQLVHFLRNHK--QEKHLVFFSTCACVEYYGKALEVLVKGVKI- 296
Query: 462 QDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESY 521
+HG + K+ +I ++ FR G+LV T+V ARG+DIPEV+ V+Q PP + ++
Sbjct: 297 ---MCIHGKMKYKRNKIFME-FRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAF 352
Query: 522 IHRSGRTGRAGRTGVCICFYQHKEE 546
+HR GRT R G G + F EE
Sbjct: 353 VHRCGRTARIGHGGSALVFLLPMEE 377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,810,472
Number of Sequences: 37866
Number of extensions: 1574389
Number of successful extensions: 19784
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 414
Number of HSP's successfully gapped in prelim test: 1035
Number of HSP's that attempted gapping in prelim test: 8943
Number of HSP's gapped (non-prelim): 6511
length of query: 783
length of database: 18,247,518
effective HSP length: 110
effective length of query: 673
effective length of database: 14,082,258
effective search space: 9477359634
effective search space used: 9477359634
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.