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Search of human proteins with 50658075
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50658075 phosphodiesterase 4D interacting protein isoform 3
[Homo sapiens]
(310 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50658075 phosphodiesterase 4D interacting protein isoform 3 [... 632 0.0
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 325 3e-89
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 325 3e-89
gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [... 325 3e-89
gi|88943074 PREDICTED: similar to Phosphodiesterase 4D interacti... 248 4e-66
gi|169161476 PREDICTED: hypothetical protein [Homo sapiens] 172 3e-43
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 127 1e-29
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 127 1e-29
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 54 1e-07
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 52 7e-07
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 51 1e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 51 1e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 50 3e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 50 3e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 7e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 2e-05
gi|148746195 trichohyalin [Homo sapiens] 46 4e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 46 4e-05
gi|42794779 myosin 18A isoform b [Homo sapiens] 46 5e-05
gi|28416946 myosin 18A isoform a [Homo sapiens] 46 5e-05
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 45 6e-05
gi|55770834 centromere protein F [Homo sapiens] 45 6e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 45 6e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 45 6e-05
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap... 45 8e-05
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 45 8e-05
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap... 45 8e-05
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap... 45 8e-05
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 45 8e-05
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 45 1e-04
>gi|50658075 phosphodiesterase 4D interacting protein isoform 3
[Homo sapiens]
Length = 310
Score = 632 bits (1629), Expect = 0.0
Identities = 310/310 (100%), Positives = 310/310 (100%)
Query: 1 MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSW 60
MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSW
Sbjct: 1 MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSW 60
Query: 61 AAAAEEEEAAAAATPWMRDYFAEDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKV 120
AAAAEEEEAAAAATPWMRDYFAEDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKV
Sbjct: 61 AAAAEEEEAAAAATPWMRDYFAEDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKV 120
Query: 121 PFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRED 180
PFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRED
Sbjct: 121 PFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRED 180
Query: 181 IYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYE 240
IYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYE
Sbjct: 181 IYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYE 240
Query: 241 LLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQ 300
LLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQ
Sbjct: 241 LLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQ 300
Query: 301 YTEALAQRDK 310
YTEALAQRDK
Sbjct: 301 YTEALAQRDK 310
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 325 bits (833), Expect = 3e-89
Identities = 164/168 (97%), Positives = 165/168 (98%)
Query: 143 RDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 202
R +HLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK
Sbjct: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65
Query: 203 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 262
KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR
Sbjct: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125
Query: 263 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 310
MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK
Sbjct: 126 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 24/143 (16%)
Query: 140 QALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL 199
+ +R E+ L D K+ + F+E + E +E +K N EL+ ++ L+ EL
Sbjct: 360 RVVRQKERQLADAKQ-------CVQFVEAAAHES-EQQKEASWKHNQELRKALQQLQEEL 411
Query: 200 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNE 259
Q+K Q L + W EAE + ++Q +H+ L +K QLLQE L +
Sbjct: 412 QNKSQQL-RAW----------EAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYR 460
Query: 260 AARMAALVEAEKECNLELSEKLK 282
L E N L EKL+
Sbjct: 461 DNSDKTL-----EANEMLLEKLR 478
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 325 bits (833), Expect = 3e-89
Identities = 164/168 (97%), Positives = 165/168 (98%)
Query: 143 RDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 202
R +HLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK
Sbjct: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65
Query: 203 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 262
KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR
Sbjct: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125
Query: 263 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 310
MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK
Sbjct: 126 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 24/143 (16%)
Query: 140 QALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL 199
+ +R E+ L D K+ + F+E + E +E +K N EL+ ++ L+ EL
Sbjct: 360 RVVRQKERQLADAKQ-------CVQFVEAAAHES-EQQKEASWKHNQELRKALQQLQEEL 411
Query: 200 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNE 259
Q+K Q L + W EAE + ++Q +H+ L +K QLLQE L +
Sbjct: 412 QNKSQQL-RAW----------EAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYR 460
Query: 260 AARMAALVEAEKECNLELSEKLK 282
L E N L EKL+
Sbjct: 461 DNSDKTL-----EANEMLLEKLR 478
Score = 36.2 bits (82), Expect = 0.038
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 191 EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQ 250
E ESL+ L + HL + E EL Q ERQQ E + E + + +
Sbjct: 1928 ETESLREALLSSRSHLQEL-----------EKELEHQKVERQQLLEDLREKQQEVLHFRE 1976
Query: 251 EESRLAKNEAARMAALVEAEKEC--NLELSEKLKGVTKNWEDVPGDQVK 297
E L +N++ LV +++C +L E L+ + +E + G+ K
Sbjct: 1977 ERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKK 2025
>gi|50658077 phosphodiesterase 4D interacting protein isoform 4
[Homo sapiens]
Length = 173
Score = 325 bits (833), Expect = 3e-89
Identities = 164/168 (97%), Positives = 165/168 (98%)
Query: 143 RDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 202
R +HLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK
Sbjct: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65
Query: 203 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 262
KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR
Sbjct: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125
Query: 263 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 310
MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK
Sbjct: 126 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173
>gi|88943074 PREDICTED: similar to Phosphodiesterase 4D interacting
protein [Homo sapiens]
Length = 134
Score = 248 bits (634), Expect = 4e-66
Identities = 125/127 (98%), Positives = 126/127 (99%)
Query: 184 RNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 243
+N ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE
Sbjct: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
Query: 244 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 303
NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE
Sbjct: 68 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 127
Query: 304 ALAQRDK 310
ALAQRDK
Sbjct: 128 ALAQRDK 134
>gi|169161476 PREDICTED: hypothetical protein [Homo sapiens]
Length = 109
Score = 172 bits (436), Expect = 3e-43
Identities = 78/78 (100%), Positives = 78/78 (100%)
Query: 1 MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSW 60
MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSW
Sbjct: 1 MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSW 60
Query: 61 AAAAEEEEAAAAATPWMR 78
AAAAEEEEAAAAATPWMR
Sbjct: 61 AAAAEEEEAAAAATPWMR 78
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 127 bits (320), Expect = 1e-29
Identities = 70/148 (47%), Positives = 97/148 (65%)
Query: 142 LRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 201
++DFE + +LKKENF+LKLRIYFLEERMQQ++ E IYK NIELKVEVESLKRELQ+
Sbjct: 60 MKDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQE 119
Query: 202 KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAA 261
++Q L K VE+L +E++R E+ +++ + V +LL +I LL+++ A+ E
Sbjct: 120 REQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELE 179
Query: 262 RMAALVEAEKECNLELSEKLKGVTKNWE 289
+ A E EK L L KL + K E
Sbjct: 180 KAFAGTETEKALRLRLESKLSEMKKMHE 207
Score = 32.0 bits (71), Expect = 0.72
Identities = 40/161 (24%), Positives = 70/161 (43%), Gaps = 22/161 (13%)
Query: 139 TQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRE-----DIYKRNIE-LKVEV 192
T A + EK + E +L+LR+ M++ +E D R IE LK+ +
Sbjct: 172 TAAQAELEKAFAGTETEK-ALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSL 230
Query: 193 ESLKRELQDKKQHLDKTWADVENLNSQN--------EAELRRQFEERQQETEHVYELLEN 244
+S + +Q K+ + EN++S E R+ E Q E + E
Sbjct: 231 KSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEE 290
Query: 245 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 285
+IQ L+E+ R + E A EK+ +L+ + ++G+T
Sbjct: 291 RIQALEEDLREKEREIA-------TEKKNSLKRDKAIQGLT 324
Score = 31.2 bits (69), Expect = 1.2
Identities = 29/112 (25%), Positives = 61/112 (54%), Gaps = 15/112 (13%)
Query: 140 QALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL 199
++++ + L+DL++E L+ LEE ++K S+ D R +L+ EVE L+ E+
Sbjct: 399 RSIKKITQELSDLQQERERLEKD---LEEAHREK---SKGDCTIR--DLRNEVEKLRNEV 450
Query: 200 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 251
++++ ++ + ++L S++ +L Q +Q +H+ E K LLQ+
Sbjct: 451 NEREKAMENRY---KSLLSESNKKLHNQ----EQVIKHLTESTNQKDVLLQK 495
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 127 bits (320), Expect = 1e-29
Identities = 70/148 (47%), Positives = 97/148 (65%)
Query: 142 LRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 201
++DFE + +LKKENF+LKLRIYFLEERMQQ++ E IYK NIELKVEVESLKRELQ+
Sbjct: 60 MKDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQE 119
Query: 202 KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAA 261
++Q L K VE+L +E++R E+ +++ + V +LL +I LL+++ A+ E
Sbjct: 120 REQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELE 179
Query: 262 RMAALVEAEKECNLELSEKLKGVTKNWE 289
+ A E EK L L KL + K E
Sbjct: 180 KAFAGTETEKALRLRLESKLSEMKKMHE 207
Score = 32.0 bits (71), Expect = 0.72
Identities = 40/161 (24%), Positives = 70/161 (43%), Gaps = 22/161 (13%)
Query: 139 TQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRE-----DIYKRNIE-LKVEV 192
T A + EK + E +L+LR+ M++ +E D R IE LK+ +
Sbjct: 172 TAAQAELEKAFAGTETEK-ALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSL 230
Query: 193 ESLKRELQDKKQHLDKTWADVENLNSQN--------EAELRRQFEERQQETEHVYELLEN 244
+S + +Q K+ + EN++S E R+ E Q E + E
Sbjct: 231 KSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEE 290
Query: 245 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 285
+IQ L+E+ R + E A EK+ +L+ + ++G+T
Sbjct: 291 RIQALEEDLREKEREIA-------TEKKNSLKRDKAIQGLT 324
Score = 31.2 bits (69), Expect = 1.2
Identities = 29/112 (25%), Positives = 61/112 (54%), Gaps = 15/112 (13%)
Query: 140 QALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL 199
++++ + L+DL++E L+ LEE ++K S+ D R +L+ EVE L+ E+
Sbjct: 399 RSIKKITQELSDLQQERERLEKD---LEEAHREK---SKGDCTIR--DLRNEVEKLRNEV 450
Query: 200 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 251
++++ ++ + ++L S++ +L Q +Q +H+ E K LLQ+
Sbjct: 451 NEREKAMENRY---KSLLSESNKKLHNQ----EQVIKHLTESTNQKDVLLQK 495
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 54.3 bits (129), Expect = 1e-07
Identities = 65/256 (25%), Positives = 110/256 (42%), Gaps = 30/256 (11%)
Query: 45 QTPSRERRRPEPAGSWAAAAEEEEAAAAATPWMRDYFAEDDGEMVPRTSHTAAFLSDTKD 104
Q + + P P + E+ A P + AED E V +S T
Sbjct: 521 QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEE--AEDPEEKVA--------VSPT-- 568
Query: 105 RGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIY 164
PPV ++ RS E V + S A + + Q L ++HL + K+E +LR
Sbjct: 569 --PPVSPEV-RSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQ-QLREK 624
Query: 165 FLEE------RMQQKYEASREDIYKRNIELKVEVESLKRELQDKK------QHLDKTWAD 212
+E R+ Q+ E S + +R + E E+ RE + ++ Q T AD
Sbjct: 625 LCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 684
Query: 213 VENLNSQNEAELRRQFEE--RQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAE 270
+ + ++ EA L++ EE QQ+ E +N+ L Q + + +E + AAL A+
Sbjct: 685 EDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK 744
Query: 271 KECNLELSEKLKGVTK 286
++ +L E+L+G K
Sbjct: 745 EKALQQLREQLEGERK 760
Score = 31.2 bits (69), Expect = 1.2
Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 10/124 (8%)
Query: 138 QTQALRDFEKHLNDLKK-ENFSLKLRIYFLEERMQQKYEAS-REDIYKRNIELKVEVESL 195
Q +L+ + L +K E SL+ + + E+++++ EAS + + N + ++ L
Sbjct: 692 QEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQL 751
Query: 196 KRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQ--EES 253
+ +L+ +++ V L ++ AEL R + + V L+ KIQ Q EE+
Sbjct: 752 REQLEGERKEA------VATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEA 805
Query: 254 RLAK 257
+L K
Sbjct: 806 QLQK 809
Score = 30.0 bits (66), Expect = 2.7
Identities = 47/219 (21%), Positives = 86/219 (39%), Gaps = 53/219 (24%)
Query: 132 EKPPQVQTQALRDFEKHLNDLKKENFS-LKLRIYFLEERMQQKYEASREDIYKRNIELKV 190
E+ QV +A +E + E L + L+ +++ E R++ +KR +L+
Sbjct: 856 EEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRR 915
Query: 191 EVESLKRELQDKKQHLDKTWADVE---------------------------NLNSQNEAE 223
+R+LQD + L+ DV+ L S+
Sbjct: 916 RHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATA 975
Query: 224 LRRQFEERQQETEHVYE-----------------LLENKIQLLQEESRLAKNEAARMAAL 266
+Q EE Q+E H+ + LE+++ LLQ +S+ + + + A
Sbjct: 976 THQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEA- 1034
Query: 267 VEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEAL 305
EA+K+ +L L+ VT E+ +PD + E L
Sbjct: 1035 -EAQKKQHL-----LREVTVE-ENNASPHFEPDLHIEDL 1066
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 52.0 bits (123), Expect = 7e-07
Identities = 48/165 (29%), Positives = 85/165 (51%), Gaps = 21/165 (12%)
Query: 131 FEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKV 190
FE+ + + + L K + +++++ S K + ERMQQ+ E R++ ++++
Sbjct: 598 FERQQREELEKLESKRKLIEEMEEKQKSDKAEL----ERMQQEVETQRKETEIVQLQIRK 653
Query: 191 EVESLKR---ELQDKKQHL--DKTWADVENLNSQNEAELRRQFEER------QQETEHVY 239
+ ESLKR +++K + L +K + E L Q E EL+++ +E Q+E + +
Sbjct: 654 QEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLK 713
Query: 240 ELLEN----KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEK 280
EL N K Q+ QE +L K + + A L E EK+ LE EK
Sbjct: 714 ELNNNEKAEKFQIFQELDQLQKEKDEQYAKL-ELEKK-RLEEQEK 756
Score = 29.3 bits (64), Expect = 4.7
Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
Query: 190 VEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRR---QFEERQQETEHVYELLENKI 246
+E E +RE +K + K ++E ++AEL R + E +++ETE V + +
Sbjct: 596 LEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQE 655
Query: 247 QLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWED 290
+ L+ S +N+ + A E +E L ++++ K E+
Sbjct: 656 ESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEE 699
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/160 (24%), Positives = 84/160 (52%), Gaps = 7/160 (4%)
Query: 136 QVQTQALRDFEKHLNDLKKENFSLKLRIYFLEE---RMQQKYEASREDIYKRNIELKVEV 192
+++ L + + +L+KEN +L I +E R+++ + ++E + + I++K V
Sbjct: 846 EIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLV 905
Query: 193 ESLKRELQDKKQHLDKTWADVENLNSQNE--AELRRQFEERQQETEHVYELLENKIQ-LL 249
+L+ +L +K + D+E L + E + + +Q T+ Y+LLE+K++ L
Sbjct: 906 -TLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTL 964
Query: 250 QEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 289
++ + + + A + A +E N +L ++LK V KN+E
Sbjct: 965 KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYE 1004
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 10/146 (6%)
Query: 146 EKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQH 205
E+ + L++EN L + L +R Q EA +DI K N K+ ES+K +
Sbjct: 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKEN---KILHESIK----ETSSK 602
Query: 206 LDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA 265
L K + E + E E ++ ER +E E+ LE + +LLQ++ K ++ A
Sbjct: 603 LSK--IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Query: 266 LVEAEKECNLELSEKLKGVTKNWEDV 291
L + E E + KLK +++++
Sbjct: 661 LEQENSELERE-NRKLKKTLDSFKNL 685
Score = 38.5 bits (88), Expect = 0.008
Identities = 38/151 (25%), Positives = 75/151 (49%), Gaps = 17/151 (11%)
Query: 136 QVQTQALR-DFEKHLNDLKKENFSLKLRIYFLEERMQQKY---EASREDIYKRNIELKVE 191
+++TQ + D EK ++L+K + K R+ E+ +Y E+ E K+++E+K E
Sbjct: 915 KLKTQQMNNDLEKLTHELEKIGLN-KERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEE 973
Query: 192 -VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQ---------QETEHVYEL 241
+ +L+ L++ + + +++ + EA +RQ EER ++ + E
Sbjct: 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERES 1033
Query: 242 LENKIQLLQEESRLAKNEAARMAALVEAEKE 272
E +LL+ + RL E R A ++AEK+
Sbjct: 1034 QETTRELLKVKDRLI--EVERNNATLQAEKQ 1062
Score = 35.0 bits (79), Expect = 0.085
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 24/205 (11%)
Query: 102 TKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKL 161
T DR ++S++ + +K ++ + A E + T + + L +KK +LK
Sbjct: 949 TDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1008
Query: 162 RIYFLEERMQQ----------KYEASREDIYKRNIELK---VEVESLKRELQDKKQHLDK 208
R EERM Q K+E ++ + +++K +EVE LQ +KQ L
Sbjct: 1009 RQD--EERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKT 1066
Query: 209 TWADVENLNSQNEAE---LRRQFEERQQ-----ETEHVYELLENKIQLLQEESRLAKN-E 259
+E N+ +A+ L+RQ Q+ +T++ +EN Q S + +N +
Sbjct: 1067 QLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1126
Query: 260 AARMAALVEAEKECNLELSEKLKGV 284
+ +E E E ++ E LK +
Sbjct: 1127 LLIQQSSLENENESVIKEREDLKSL 1151
Score = 34.7 bits (78), Expect = 0.11
Identities = 42/191 (21%), Positives = 85/191 (44%), Gaps = 27/191 (14%)
Query: 136 QVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRED--IYKRNIELKVEVE 193
++ + + E+ ++L++EN LK + + Q +E+ + + N+EL+ VE
Sbjct: 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVE 711
Query: 194 SLK-------------RELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYE 240
SLK +EL+ +K+ L K ++ + + L ++ E + + +
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQL-KKGLELLKASFKKTERLEVSYQGLDIENQRLQK 770
Query: 241 LLENKIQLLQE-ESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPD 299
LEN + +Q+ ES L +E E + + E+LK +K E + + +
Sbjct: 771 TLENSNKKIQQLESELQD---------LEMENQTLQKNLEELKISSKRLEQLEKENKSLE 821
Query: 300 QYTEALAQRDK 310
Q T L ++DK
Sbjct: 822 QETSQL-EKDK 831
Score = 32.3 bits (72), Expect = 0.55
Identities = 28/105 (26%), Positives = 54/105 (51%), Gaps = 10/105 (9%)
Query: 183 KRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS---QNEAELRRQFEERQQETEHVY 239
K N L +VE L+ E+ +KQ L + +NL+ + +A+L + E ++ +E
Sbjct: 498 KENQRLSKKVEILENEIVQEKQSLQ----NCQNLSKDLMKEKAQLEKTIETLRENSERQI 553
Query: 240 ELLENKIQLLQE--ESRLAKNEAARMAALVEAEKECNLELSEKLK 282
++LE + + L + S +++ + A + + EKE N L E +K
Sbjct: 554 KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE-NKILHESIK 597
Score = 28.9 bits (63), Expect = 6.1
Identities = 34/152 (22%), Positives = 64/152 (42%), Gaps = 44/152 (28%)
Query: 173 KYEASREDIYKRNIELKVEVESLKRELQDK-------KQHLDKTWADV-----ENLNSQN 220
K SR+ + + K ++ L++EL++K KQ L++ ++ EN+N +
Sbjct: 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS 300
Query: 221 EAELRRQFEE--------------------RQQETEHVYELLENKIQLLQEESRL----- 255
+A R + + R +E H E + +++ L+E++++
Sbjct: 301 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK 360
Query: 256 ------AKNEAARMAALVEAEKECNLELSEKL 281
+ AR L E EKE NL+L KL
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKE-NLQLKAKL 391
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 51.2 bits (121), Expect = 1e-06
Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 139 TQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRE 198
T++L D E ++ KE ++ R+ L+E + K + N L ESLK
Sbjct: 1517 TKSLADVESQVSAQNKEKDTVLGRLALLQEE-RDKLITEMDRSLLENQSLSSSCESLKLA 1575
Query: 199 LQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN 258
L+ + +K ++E+L S AE +++E+ +E + YE+L LQ ++ N
Sbjct: 1576 LEGLTEDKEKLVKEIESLKSSKIAE-STEWQEKHKELQKEYEIL------LQSYENVS-N 1627
Query: 259 EAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQR 308
EA R+ +VEA ++ EL KL+ N ++ + +Q E + ++
Sbjct: 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677
Score = 42.0 bits (97), Expect = 7e-04
Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 27/166 (16%)
Query: 140 QALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL 199
+ +R H++DL EN L + E + Q ++ K+ +E++++ +EL
Sbjct: 2510 EEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI-TIKDSQQKQLLEVQLQ---QNKEL 2565
Query: 200 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN----------KIQLL 249
++K L++ + E N +LRR F Q+E + + + +E+ ++ L
Sbjct: 2566 ENKYAKLEEKLKESEEANE----DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2621
Query: 250 QEESRLA---------KNEAARMAALVEAEKECNLELSEKLKGVTK 286
QEE L + E R++AL + ++ EL E+L V K
Sbjct: 2622 QEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2667
Score = 39.7 bits (91), Expect = 0.003
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 142 LRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 201
L K++ ++K + ++ L Q + + S+ D K + E ++E+E +K +LQ+
Sbjct: 104 LTSLNKYIEEMKAQGGTV------LPTEPQSEEQLSKHD--KSSTEEEMEIEKIKHKLQE 155
Query: 202 KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAA 261
K++ + A + ++ A+ + EE + + E E I LQ ++L++ +A
Sbjct: 156 KEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQE-KEEFISTLQ--AQLSQTQAE 212
Query: 262 RMAALVEAEKECNLELSEKL 281
+ A V EK+ E +L
Sbjct: 213 QAAQQVVREKDARFETQVRL 232
Score = 37.7 bits (86), Expect = 0.013
Identities = 32/147 (21%), Positives = 70/147 (47%), Gaps = 5/147 (3%)
Query: 154 KENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADV 213
++N L+ + LEE++++ EA+ ED+ + L+ E + L +E++ K + + V
Sbjct: 2560 QQNKELENKYAKLEEKLKESEEAN-EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV 2618
Query: 214 ENLNSQNEAEL-RRQFEERQQETEHVYELL---ENKIQLLQEESRLAKNEAARMAALVEA 269
L + L Q + +++E + L + +I L+EE + EAA+ +E
Sbjct: 2619 TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIED 2678
Query: 270 EKECNLELSEKLKGVTKNWEDVPGDQV 296
+ + L+ G+ +N + ++V
Sbjct: 2679 KLKKELKHLHHDAGIMRNETETAEERV 2705
Score = 37.4 bits (85), Expect = 0.017
Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 29/179 (16%)
Query: 118 EKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEAS 177
EK V+T EK QV + EK + L +E FSL + I L+E++ A
Sbjct: 884 EKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQ-LNEEKFSLGVEIKTLKEQLNLLSRA- 941
Query: 178 REDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE----ERQQ 233
E+ K +E EV S L + + ++ ++ EL+ +F+ E +Q
Sbjct: 942 -EEAKKEQVEEDNEVSS----------GLKQNYDEMSPAGQISKEELQHEFDLLKKENEQ 990
Query: 234 ETEHVYELLENKIQLLQEESRL------AKNEAARMAALVEAEK------ECNLELSEK 280
+ L N+ +LLQ SRL K+E+ + L E E+ + N E SEK
Sbjct: 991 RKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEK 1049
Score = 35.4 bits (80), Expect = 0.065
Identities = 26/131 (19%), Positives = 64/131 (48%), Gaps = 11/131 (8%)
Query: 165 FLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAEL 224
F E+++ +ASRE + + E+ ++ + + L K++ + A EL
Sbjct: 2354 FSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIA-----------EL 2402
Query: 225 RRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV 284
R+Q ++ +E E++ E + +L+EE++ A ++ ++ ++ K+ N++ +L
Sbjct: 2403 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSF 2462
Query: 285 TKNWEDVPGDQ 295
K+ + D+
Sbjct: 2463 VKSMSSLQNDR 2473
Score = 34.3 bits (77), Expect = 0.14
Identities = 43/203 (21%), Positives = 88/203 (43%), Gaps = 39/203 (19%)
Query: 136 QVQTQALRDFEK---HLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEV 192
+ + Q D+E H N L ++ SL + + +++ + +D+ + E +
Sbjct: 775 EAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEV-LQNELDDVQLQFSEQSTLI 833
Query: 193 ESLKRELQDKK----------QHLDKTWADVENLNSQNEAE-----------------LR 225
SL+ +LQ+K+ +H+ ++ SQ E E L+
Sbjct: 834 RSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQ 893
Query: 226 RQFEER-QQETEHVYELLENKIQLLQE------ESRLAKNEAARMAALVEAEKECNLELS 278
+ EE+ QQ TE + + E +QL +E E + K + ++ EA+KE E +
Sbjct: 894 QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDN 953
Query: 279 EKLKGVTKNWEDV-PGDQVKPDQ 300
E G+ +N++++ P Q+ ++
Sbjct: 954 EVSSGLKQNYDEMSPAGQISKEE 976
Score = 33.1 bits (74), Expect = 0.32
Identities = 38/207 (18%), Positives = 86/207 (41%), Gaps = 31/207 (14%)
Query: 128 LRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQ---KYEASREDIYKR 184
LR ++ + ++L + ++ L++E + + R L +++QQ ++ R +
Sbjct: 254 LRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETE 313
Query: 185 NIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNE------AELRRQFE--------E 230
E K+ +E ++ E+ ++K ++ +L Q E AEL ++ E
Sbjct: 314 REESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAE 373
Query: 231 RQQETEHVYELL--------------ENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 276
+++T H+ L + +LLQ+++ A A + L + ++ + E
Sbjct: 374 MEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 433
Query: 277 LSEKLKGVTKNWEDVPGDQVKPDQYTE 303
+S+ L + + PD Y E
Sbjct: 434 ISQFLNRLPLQQHETASQTSFPDVYNE 460
Score = 32.7 bits (73), Expect = 0.42
Identities = 44/216 (20%), Positives = 94/216 (43%), Gaps = 36/216 (16%)
Query: 111 SQIWRSGEKVPFVQTYSLRAFEKPPQVQTQA----------LRDFEKHLNDLKKE----- 155
S + R+ + + FVQT S + E + QA L F+ L+D + E
Sbjct: 2036 SALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVL 2095
Query: 156 --NFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK-------KQHL 206
N LK + +E ++ + + ED+ +R + + + K+ +Q+K K HL
Sbjct: 2096 ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHL 2155
Query: 207 DKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMA-- 264
++T +++ ++ + E+ +Q +E T + LQ++ +EA +
Sbjct: 2156 EETIGEIQVTLNKKDKEV-QQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERK 2214
Query: 265 ---ALVEAEKECNLE------LSEKLKGVTKNWEDV 291
A+ E+E L+ L ++L+ ++ + E++
Sbjct: 2215 FSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2250
Score = 32.7 bits (73), Expect = 0.42
Identities = 34/159 (21%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Query: 128 LRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIE 187
L+ E+ + ++ ++ DL KE SLK+ I L ++ E +Y + +
Sbjct: 2576 LKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLY--HAQ 2633
Query: 188 LKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQ 247
LKV+ E + R L ++ + ++ E EL +E ++ + + L+ +++
Sbjct: 2634 LKVKEEEVHR--------LSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELK 2685
Query: 248 LLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTK 286
L ++ + +NE V +E+ +KL VTK
Sbjct: 2686 HLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2724
Score = 30.8 bits (68), Expect = 1.6
Identities = 24/90 (26%), Positives = 48/90 (53%), Gaps = 10/90 (11%)
Query: 166 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNE--AE 223
LEE++ E +E + K+ E +++ ++ Q+K++HL E L Q +
Sbjct: 1162 LEEKILA-LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLR------EELKQQKDDYNR 1214
Query: 224 LRRQFEERQQETEHVYELLENKIQLLQEES 253
L+ QF+E+ +E E++ + L ++Q+ ES
Sbjct: 1215 LQEQFDEQSKENENIGDQL-RQLQIQVRES 1243
Score = 28.9 bits (63), Expect = 6.1
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 25/121 (20%)
Query: 180 DIYKRNIELKVEVESLKR---ELQDKKQHLDKTWADVENL-----------------NSQ 219
D +N L+ E+++LK+ EL+++KQ L K VE+ N
Sbjct: 1946 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKS 2005
Query: 220 NEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSE 279
+ EL+ +E+QQE + + K + +E A + V+ E + +LE+++
Sbjct: 2006 HAKELQELLKEKQQEVKQL-----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITK 2060
Query: 280 K 280
+
Sbjct: 2061 E 2061
Score = 28.9 bits (63), Expect = 6.1
Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 21/132 (15%)
Query: 187 ELKVEVESLKRELQDKKQHLDKTWADVE-------NLNSQNEAELRRQFEERQQETEHVY 239
ELK+ + L+ DK+ K +V+ L +N+ EL Q EE T H+Y
Sbjct: 2249 ELKINISRLEH---DKQIWESKAQTEVQLQQKVCDTLQGENK-ELLSQLEE----TRHLY 2300
Query: 240 ELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE-DVPGDQVKP 298
+N++ L+ E + K++ ++ +E K E L+G+ + E D+ +
Sbjct: 2301 HSSQNELAKLESELKSLKDQLTDLSNSLEKCK----EQKGNLEGIIRQQEADIQNSKFSY 2356
Query: 299 DQY-TEALAQRD 309
+Q T+ A R+
Sbjct: 2357 EQLETDLQASRE 2368
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.7 bits (117), Expect = 3e-06
Identities = 39/180 (21%), Positives = 90/180 (50%), Gaps = 10/180 (5%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ ++WR EK+ Q +R E+ Q + +R+ ++ + + ++E + + +I EE+
Sbjct: 345 EDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE 229
Q+K + + +++ +++ + E + R+ ++K + L++ D E E R+ E
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQ-EEKIRELEEMMQDQE--------EKLREVE 454
Query: 230 ERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 289
E+ QE E + E KIQ +E+ + + + R L++ E++ + + + K WE
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Score = 45.8 bits (107), Expect = 5e-05
Identities = 36/151 (23%), Positives = 76/151 (50%), Gaps = 16/151 (10%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ ++WR EK+ R E+ Q Q + LR+ E+ + + +++ + +I EE+
Sbjct: 426 EEEMWRQEEKI--------RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK 477
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE 229
+Q++ E +++ LK E + ++E + +Q +K W E + Q E R++ +
Sbjct: 478 IQEQ----EEKTWRQEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQEEKMQRQEEK 532
Query: 230 ERQQET---EHVYELLENKIQLLQEESRLAK 257
R+QE + ++ E +++L + E RL K
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/187 (19%), Positives = 88/187 (47%), Gaps = 15/187 (8%)
Query: 136 QVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERM---QQKYEASREDIYKRNIELKVEV 192
Q Q + + E+ + + +++ +L+I EE+M ++K E I ++ ++ +
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 193 ESLKRELQDKKQHLDKTWADVENLNSQN------EAELRRQFEERQQETEHVYELL---E 243
E ++ + + ++ +K W E + Q+ E E+ RQ E+ +++ E E + E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 244 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 303
K++ E+ R + E R + +E + EKL+ V + ++ ++ K + E
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE---EEEKMQEQEE 469
Query: 304 ALAQRDK 310
+ ++++
Sbjct: 470 KIQRQEE 476
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.7 bits (117), Expect = 3e-06
Identities = 39/180 (21%), Positives = 90/180 (50%), Gaps = 10/180 (5%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ ++WR EK+ Q +R E+ Q + +R+ ++ + + ++E + + +I EE+
Sbjct: 345 EDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE 229
Q+K + + +++ +++ + E + R+ ++K + L++ D E E R+ E
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQ-EEKIRELEEMMQDQE--------EKLREVE 454
Query: 230 ERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 289
E+ QE E + E KIQ +E+ + + + R L++ E++ + + + K WE
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Score = 45.8 bits (107), Expect = 5e-05
Identities = 36/151 (23%), Positives = 76/151 (50%), Gaps = 16/151 (10%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ ++WR EK+ R E+ Q Q + LR+ E+ + + +++ + +I EE+
Sbjct: 426 EEEMWRQEEKI--------RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK 477
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE 229
+Q++ E +++ LK E + ++E + +Q +K W E + Q E R++ +
Sbjct: 478 IQEQ----EEKTWRQEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQEEKMQRQEEK 532
Query: 230 ERQQET---EHVYELLENKIQLLQEESRLAK 257
R+QE + ++ E +++L + E RL K
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/187 (19%), Positives = 88/187 (47%), Gaps = 15/187 (8%)
Query: 136 QVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERM---QQKYEASREDIYKRNIELKVEV 192
Q Q + + E+ + + +++ +L+I EE+M ++K E I ++ ++ +
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 193 ESLKRELQDKKQHLDKTWADVENLNSQN------EAELRRQFEERQQETEHVYELL---E 243
E ++ + + ++ +K W E + Q+ E E+ RQ E+ +++ E E + E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 244 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 303
K++ E+ R + E R + +E + EKL+ V + ++ ++ K + E
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE---EEEKMQEQEE 469
Query: 304 ALAQRDK 310
+ ++++
Sbjct: 470 KIQRQEE 476
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.5 bits (114), Expect = 7e-06
Identities = 42/180 (23%), Positives = 86/180 (47%), Gaps = 19/180 (10%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
Q +IWR EK+ Q +R E+ Q + +R+ E+ + + ++ +++ EE+
Sbjct: 488 QEEIWRQKEKM-HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE-------KMWRQEEK 539
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDK--------KQHLDKTWADVENLNSQNE 221
++++ E RE+ K + + K+ E ++E +DK ++ +K W E + Q E
Sbjct: 540 IREQEEMWREE-EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 222 AELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 281
R++ EE+ + E E KIQ +E+ R + + + + ++E E EK+
Sbjct: 599 K--RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
Score = 43.5 bits (101), Expect = 2e-04
Identities = 34/197 (17%), Positives = 94/197 (47%), Gaps = 11/197 (5%)
Query: 65 EEEEAAAAATPWMRDYFAEDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQ 124
EE+ W ++ + E V R + + +++ + ++W+ EK+ Q
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEK---IREQEEKRQEQEEKMWKQEEKIR-EQ 617
Query: 125 TYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEA---SREDI 181
++ E+ + Q + +R+ E+ + +++ + ++ EE+MQ++ E E I
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677
Query: 182 YKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 241
++ +++ + E ++ + + ++ +K W E + Q E ++ + R+QE ++
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE----KM 733
Query: 242 LENKIQLLQEESRLAKN 258
E +++L Q+E ++ ++
Sbjct: 734 WEQEVRLRQQEEKMQEH 750
Score = 40.4 bits (93), Expect = 0.002
Identities = 46/206 (22%), Positives = 96/206 (46%), Gaps = 20/206 (9%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKEN--FSLKLRIYFLE 167
+ +W EK+ + +EK +++ Q +EK ++E + + +I LE
Sbjct: 341 EEMMWEKEEKM---RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 168 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 227
E+M ++ E RE KR E K+ RE + +++ K W E + Q E ++R Q
Sbjct: 398 EKMHEQ-EKIREQEEKRQEEEKI------REQEKRQEQEAKMWRQEEKIREQEE-KIREQ 449
Query: 228 FEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKEC---NLELSEKLKGV 284
++ ++ E ++E + KI+ +EE R + E R + ++E ++ E+ + +
Sbjct: 450 EKKMWRQEEKIHE--QEKIR--EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Query: 285 TKNWEDVPGDQVKPDQYTEALAQRDK 310
K E V + K + E + ++++
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEE 531
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/155 (20%), Positives = 78/155 (50%), Gaps = 15/155 (9%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ ++WR EK+ + +E+ Q Q + +R+ E+ + + +++ + ++ EE+
Sbjct: 299 EEKMWRQEEKI--------QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
Query: 170 MQQKYEA--SREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 227
M+++ E +E+ +R E+ E E R ++ ++ ++E +E E R+
Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE--KMHEQEKIRE 408
Query: 228 FEERQQETEHVYE---LLENKIQLLQEESRLAKNE 259
EE++QE E + E E + ++ ++E ++ + E
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 443
Score = 38.9 bits (89), Expect = 0.006
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 24/161 (14%)
Query: 146 EKHLNDLKKENFSLKLRIY---FLEERMQQKYEASREDIY---KRNIELKVEVESLKREL 199
++++ +L KE +L L +Y +E +++K +E + E+++ V+ LKR+L
Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL 251
Query: 200 QDKK------------QHLDKTWADVE-NLNSQNEAE-----LRRQFEERQQETEHVYEL 241
+ K HL K V L +Q E L +Q EE+ E +
Sbjct: 252 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 242 LENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 282
E KIQ +E+ R + + + ++E E EK++
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Score = 34.7 bits (78), Expect = 0.11
Identities = 23/128 (17%), Positives = 69/128 (53%), Gaps = 11/128 (8%)
Query: 138 QTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRN--IELKVEVESL 195
Q + +R+ E+ + + +K+ + + +I+ E+ +++ +E+++++ I + E+
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 196 KRELQDKKQHL----DKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 251
K ++ ++++ + +K W E + Q E ++R Q E+ ++ E + E + ++ +E
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEE-KIREQEEKMWRQEEKIRE----QEEMWRE 549
Query: 252 ESRLAKNE 259
E ++ + E
Sbjct: 550 EEKMHEQE 557
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/191 (24%), Positives = 88/191 (46%), Gaps = 31/191 (16%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ ++WR E++ Q +R E+ + Q + LR+ EK L + +KE K ++ EE+
Sbjct: 254 EEKMWRQEERLR-EQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK-KLREQEEQ 311
Query: 170 MQQKYEA----------SREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQ 219
MQ++ E E ++++ L + + ++ + Q + ++ W E L
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL--- 368
Query: 220 NEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSE 279
R+ EER +E E ++E E +QEE R+ + E + E+E E E
Sbjct: 369 ------REKEERMREQEKMWEQEEK----MQEEERIREREKK-----MREEEETMREQEE 413
Query: 280 KLKGVTKN-WE 289
K++ +N WE
Sbjct: 414 KMQKQEENMWE 424
Score = 43.1 bits (100), Expect = 3e-04
Identities = 40/176 (22%), Positives = 86/176 (48%), Gaps = 18/176 (10%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
Q ++W+ EK+ + + EK Q + +R+ E+ + + +K+ + + EE+
Sbjct: 526 QKKMWQQEEKMR--EEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEK 582
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELRRQ 227
MQ++ E RE E K+ + K + Q++K + +K W E Q + E+ +
Sbjct: 583 MQEQEEKMREQ------EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE 636
Query: 228 FEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG 283
EE+ QE E ++ E + ++ ++E ++ + E ++ ++E E EK++G
Sbjct: 637 QEEKMQEQEE--KMWEQEEKMREQEEKMREQEEK-----MQGQEEKMREQEEKMQG 685
Score = 42.7 bits (99), Expect = 4e-04
Identities = 40/191 (20%), Positives = 86/191 (45%), Gaps = 24/191 (12%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
Q ++W G++ + +R E Q + +RD E+ + D ++ + R+ EER
Sbjct: 465 QEEMW--GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE 229
M+++ + +++ E ++ E + ++Q KTW E + E E R+ E
Sbjct: 523 MREQKKMWQQE------------EKMREEKKTQEQE-KKTWDQEEKM---REEERMRERE 566
Query: 230 ERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 289
++ +E E + E K+Q +E+ R + + ++ ++E E EK+ WE
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM------WE 620
Query: 290 DVPGDQVKPDQ 300
D+++ +
Sbjct: 621 QEEEDKMQEQE 631
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/181 (22%), Positives = 82/181 (45%), Gaps = 16/181 (8%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ Q+W EK+ Q + E+ Q + LR+ E+ + + KK ++ EE+
Sbjct: 485 EDQMWEQEEKMRD-QEQKMWDQEERMWEQDERLREKEERMREQKK--------MWQQEEK 535
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE 229
M+++ + ++ + E K+ E RE + K + ++ + E + E ++R Q E
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 230 ERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL-KGVTKNW 288
+ ++ E + E E + QEE + E +M + ++E E EK+ + K W
Sbjct: 596 KMWEQEEKMQEQEEKMWE--QEEKMWEQEEEDKM----QEQEEMMWEQEEKMQEQEEKMW 649
Query: 289 E 289
E
Sbjct: 650 E 650
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/174 (20%), Positives = 82/174 (47%), Gaps = 20/174 (11%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ + W EK+ + +R EK + + + +R+ E+ + + +++ + +++ EE+
Sbjct: 546 EKKTWDQEEKMR--EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFE 229
MQ++ E E E + ++E +DK Q ++ + E + E ++ Q E
Sbjct: 604 MQEQEEKMWEQ----------EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ-E 652
Query: 230 ERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG 283
E+ +E E E K+Q +E+ R + + ++ ++E E EK++G
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMREQEEK-------MQGQEEKMREQEEKMRG 699
Score = 37.4 bits (85), Expect = 0.017
Identities = 33/159 (20%), Positives = 76/159 (47%), Gaps = 9/159 (5%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
Q + + E+ + Q +R E+ Q + L + EK + + +++ + R++ +ER
Sbjct: 308 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 367
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVE--------NLNSQNE 221
+++K E RE E K++ E RE + K + ++T + E N+ Q E
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427
Query: 222 AELRRQ-FEERQQETEHVYELLENKIQLLQEESRLAKNE 259
E ++Q E++++ ++ E + ++ ++E ++ E
Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Score = 36.6 bits (83), Expect = 0.029
Identities = 37/159 (23%), Positives = 72/159 (45%), Gaps = 24/159 (15%)
Query: 135 PQVQTQALRD-FEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVE 193
PQVQT L++ + +L+++ ++ + EE+M ++ E RE E
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQ----EEKMWRQEERLREQ------------E 268
Query: 194 SLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQE---TEHVYELLENKIQLLQ 250
RE ++K + +K + E + E ELR Q + R+QE E ++ E + ++ +
Sbjct: 269 GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328
Query: 251 EESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 289
+E ++ + E L E EK+ + + + WE
Sbjct: 329 QEEKMWRQE----ERLWEQEKQMREQEQKMRDQEERMWE 363
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 46.2 bits (108), Expect = 4e-05
Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 19/143 (13%)
Query: 167 EERMQQKYEASR-EDIYKRNIE-----LKVEVESLKRELQDKKQHLDKT--------WAD 212
EER +QK+E R E KR E LK E E+ + E + +KQ L + W
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 213 VEN-----LNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALV 267
+E + E +LRR+ EER+++ E E Q L+ E +L + + R L+
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 268 EAEKECNLELSEKLKGVTKNWED 290
+ E+E LE + + + + E+
Sbjct: 551 KREEEKRLEQERREQRLKREQEE 573
Score = 44.7 bits (104), Expect = 1e-04
Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 166 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAE 223
L E +++ RE + EL+ E E L RE ++K+ Q L++ + + E + + E
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Query: 224 LRRQFEERQ-QETEHVY----ELLENKIQLLQEESRLAKNEAAR 262
LR + E+R+ QE E Y EL + + QLL+EE + E R
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Score = 42.4 bits (98), Expect = 5e-04
Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 5/146 (3%)
Query: 166 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAE 223
L E +++ E Y+ E++ E E L RE +K+ Q L++ + + E L + E
Sbjct: 1124 LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
Query: 224 LRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG 283
LR + E+R+QE E Y E + +++ +++ + + E EKE N K+
Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE-NAVRDNKV-- 1240
Query: 284 VTKNWEDVPGDQVKPDQYTEALAQRD 309
K E+ Q++ Q + +Q+D
Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQD 1266
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 25/155 (16%)
Query: 124 QTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEA------- 176
Q R E+ Q + Q LR+ + ++E R Y ++++QQK E
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERE------RQYRKDKKLQQKEEQLLGEEPE 979
Query: 177 -----SREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELR---- 225
RE Y+ EL+ E E L RE ++K+ Q ++ + + L + E LR
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 226 -RQFEERQQETEHVYELLENKIQLLQEESRLAKNE 259
R+ +ER+++ EL + + QLL EE + +
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 10/137 (7%)
Query: 153 KKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD--KKQHLDKTW 210
KK+ + EER +++ + RE Y+ EL+ E E L E ++ ++Q L++ +
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQ-ERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 211 ADVENLNSQNEAELR-----RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA 265
E L + E LR R+ +ER+++ EL + + QLL+EE K +
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE--KRRRQELER 1138
Query: 266 LVEAEKECNLELSEKLK 282
E+E E + L+
Sbjct: 1139 QYREEEEVQQEEEQLLR 1155
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/166 (27%), Positives = 75/166 (45%), Gaps = 27/166 (16%)
Query: 136 QVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEA---------SREDI---YK 183
Q + Q LR+ + +K + R Y EE +QQ+ E R+++ Y+
Sbjct: 1028 QEEEQLLRE------EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 184 RNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELRRQFEERQ-QETEHVY- 239
+ EL+ E E L RE +K+ Q ++ + E L + E LR + E+R+ QE E Y
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 240 ---ELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 282
E+ + + QLL+EE K + E+E E + L+
Sbjct: 1142 EEEEVQQEEEQLLREEPE--KRRRQELERQYREEEELQQEEEQLLR 1185
Score = 39.7 bits (91), Expect = 0.003
Identities = 61/267 (22%), Positives = 114/267 (42%), Gaps = 26/267 (9%)
Query: 44 RQTPSRERRRPEPAGSWAAAAEEEEAAA----AATPWMRDYFAEDDGEMVPRTSHTAAFL 99
RQ E+RR +W AEE+ +A P +R+ E R FL
Sbjct: 756 RQQQEEEQRRDF---TWQWQAEEKSERGRQRLSARPPLREQ-RERQLRAEERQQREQRFL 811
Query: 100 SDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQ--ALRDFEKHLNDLKKENF 157
+ +++ + + R E + L+ E+ Q+Q + L++ ++ +++
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS-QEQRR 870
Query: 158 SLKLRIYFLEERMQQKYE-----ASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTW 210
K R EER ++++ A +E + K L+ E E L+RE ++K+ Q ++ +
Sbjct: 871 DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY 930
Query: 211 ADVENLNSQNEAELR-----RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA 265
+ E L + E LR R+ +ER+++ +L + + QLL EE + +
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 266 LVEAE---KECNLELSEKLKGVTKNWE 289
E E +E L E+ K + WE
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWE 1017
Score = 38.9 bits (89), Expect = 0.006
Identities = 38/155 (24%), Positives = 71/155 (45%), Gaps = 22/155 (14%)
Query: 132 EKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASR-EDIYKRNIELKV 190
E+P Q + Q ++ E+ L + ++++ +ER++Q+ R E+++++ E +
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEK--------QERLEQRDRQRRDEELWRQRQEWQE 182
Query: 191 EVESLKRE--LQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQET-----------EH 237
E E LQ K H + + D E L + ELRR+ E +Q+ E
Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
Query: 238 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 272
E + + L +EE +L + E R L E E++
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/154 (23%), Positives = 73/154 (47%), Gaps = 25/154 (16%)
Query: 167 EERMQQKYEASREDIYKRNIELKVEVES----LKRELQDKKQHLDKTWADVENLNSQNEA 222
E++++++ E RE + KR E ++E E LKRE ++++ L K E
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK-----------REE 583
Query: 223 ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN------EAARMAALVEAEKECNLE 276
E R+Q +R+QE L +++ L++E R + E R L+++E+ +
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE----Q 639
Query: 277 LSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 310
+ + + + ++ ++K ++ E L QR K
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLK 673
Score = 38.1 bits (87), Expect = 0.010
Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
Query: 153 KKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQ-DKKQHLDKTWA 211
++E +LR EER +Q+ RE +R +L+ E + L+RE Q ++Q L +
Sbjct: 356 EEERREQQLRREQEEERREQQLR--REQQLRREQQLRRE-QQLRREQQLRREQQLRREQQ 412
Query: 212 DVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESR 254
+ E +LRR+ EE + E +H E E +++ QEE R
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Score = 38.1 bits (87), Expect = 0.010
Identities = 34/146 (23%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Query: 166 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR 225
L+ER +Q+ D ++ +E + ++ +RE Q + K + + L E +LR
Sbjct: 1628 LQEREEQQLHRQERD--RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
Query: 226 RQFEERQ-QETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV 284
RQ +R+ +E E E + + LQEE +L + E R E E+ E+L+
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER--KFREEEQLRQETEQEQLRRQ 1743
Query: 285 TKNWEDVPGDQVKPDQYTEALAQRDK 310
+ + + +Q++P++ + L ++++
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQER 1769
Score = 36.6 bits (83), Expect = 0.029
Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 25/150 (16%)
Query: 126 YSLRAFEKPPQVQTQALRDFEKHLN--DLKKENFSLKLRIYFLEERMQQKYEA------- 176
Y+ A ++ + + Q L++ E+ L + +K + R Y EE++QQ+ E
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 177 -----SREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELR---- 225
RE Y+++ +L+ + E L E +K+ Q +K + + E L + E LR
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 226 ---RQFEERQQETEHVYELLENKIQLLQEE 252
RQ ERQ + EL + + QLL+EE
Sbjct: 1010 KRRRQEWERQYRKKD--ELQQEEEQLLREE 1037
Score = 36.2 bits (82), Expect = 0.038
Identities = 33/149 (22%), Positives = 67/149 (44%), Gaps = 7/149 (4%)
Query: 138 QTQALRDFEKHLNDLKKENFSLK----LRIYFLEERMQQKYEASREDIYKRNIELKVEVE 193
Q + +++ K L+KE L+ R L+E +Q + R+++ + E + + +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 194 SLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEES 253
L+RE Q +++ ++ E Q E RR+ +E ++E + E E + Q L+ E
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQE---RREQQEERREQQLRREQEERREQQLRREQ 355
Query: 254 RLAKNEAARMAALVEAEKECNLELSEKLK 282
+ E E +E L ++L+
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLR 384
Score = 35.8 bits (81), Expect = 0.050
Identities = 42/184 (22%), Positives = 89/184 (48%), Gaps = 16/184 (8%)
Query: 132 EKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVE 191
E+ + Q + ++ E+ L++E + + E++++++ + RE +R +L+ E
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416
Query: 192 VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEE------RQQETE-HVYELLEN 244
+ L+RE Q +++ ++ + ++ + E L+R+ EE R++ETE H E +
Sbjct: 417 -QQLRREQQLRREQEEERH-EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ 474
Query: 245 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEA 304
+++ QEE R R L E E+ E E + + + E+ ++K + E
Sbjct: 475 QLKRDQEEER-----RERWLKLEEEERREQQERRE--QQLRREQEERREQRLKRQEEEER 527
Query: 305 LAQR 308
L QR
Sbjct: 528 LQQR 531
Score = 33.9 bits (76), Expect = 0.19
Identities = 32/125 (25%), Positives = 60/125 (48%), Gaps = 12/125 (9%)
Query: 167 EERMQQKYEASREDIYKRNIE-------LKVEVESLKRELQDKKQHLDKTWADVENLNSQ 219
E++++++ E RE KR E L+ E + L+RE +++++ L K + +
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSE-QQLRREQEERREQLLKREEEKRLEQER 562
Query: 220 NEAELRRQFEERQ-QETEHVYELLENKIQLLQE---ESRLAKNEAARMAALVEAEKECNL 275
E L+R+ EER+ Q + E + +++ QE E RL + E R+ E+
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
Query: 276 ELSEK 280
E E+
Sbjct: 623 EEPEE 627
Score = 33.9 bits (76), Expect = 0.19
Identities = 44/228 (19%), Positives = 89/228 (39%), Gaps = 19/228 (8%)
Query: 65 EEEEAAAAATPWMRDYFAEDD-----GEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEK 119
E E+ +RD ++ D GE R +DR P + Q+ R +K
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 120 VPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRE 179
+ ++ Q + Q LR+ + ++ + + L+ER +Q
Sbjct: 1306 -------EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358
Query: 180 DIYKRNIELKVEVES---LKRELQDKKQHLDKTWADVENLN--SQNEAELRRQFEERQQE 234
D R EL+ + + L+ E + ++Q ++ + E + E +LR+ + + +E
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Query: 235 TEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 282
E E + +EE ++ + E R +E E++ E K +
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERER--KFLEEEQQLRQERHRKFR 1464
Score = 33.9 bits (76), Expect = 0.19
Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 14/146 (9%)
Query: 128 LRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIY------------FLEERMQQKYE 175
LR E+ Q++ R F + L ++ K R FLEE Q + E
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 176 ASREDIYKRNIELKVEVESLKRELQDKK-QHLDKTWADVENLNSQNEAELRRQFEERQ-Q 233
R+ + + + E + L R+ +D+K ++ E E ELR Q ER+
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
Query: 234 ETEHVYELLENKIQLLQEESRLAKNE 259
E E + + + LQEE +L + E
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQE 1544
Score = 30.0 bits (66), Expect = 2.7
Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 16/162 (9%)
Query: 83 EDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQAL 142
E + E + R L + + R + Q+ R F + LR + Q+++Q
Sbjct: 1734 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Query: 143 RDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 202
+ L++E +LR ++ KY E + +L+ + + L++E +D+
Sbjct: 1794 DRKFREEEQLRQEREEQQLR----PQQRDGKYRWEEEQL-----QLEEQEQRLRQE-RDR 1843
Query: 203 KQHLDKTWADVENLNS------QNEAELRRQFEERQQETEHV 238
+ ++ +A E Q E + RRQ ER+ EH+
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
Score = 29.3 bits (64), Expect = 4.7
Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 110 QSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEER 169
+ Q+ +S E+ Q R ++ + + + + E+ LK+E+ + EE
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 170 MQQKYEASREDIYKRNIELKVEVESLKREL--QDKKQHLDKTWADVENLNSQNEAELRRQ 227
+Q E + I K +L+ E ++ + ++ + +KQ + + E + E+EL+ Q
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
Query: 228 FEER----QQETE 236
EER QQE E
Sbjct: 750 EEERAHRQQQEEE 762
Score = 28.9 bits (63), Expect = 6.1
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 20/176 (11%)
Query: 136 QVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESL 195
Q + + R+ E+ L ++E R + EE+ ++ E R+ + + + E E L
Sbjct: 1687 QERDRKFREEEQQLRRQERE------RKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 196 KRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRL 255
+R+ + K + + + E +LRRQ +R+ E + QL +ES
Sbjct: 1741 RRQ-----ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 256 AKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQ-RDK 310
E ++ E E++ +L + + WE+ +Q++ ++ + L Q RD+
Sbjct: 1796 KFREEEQLRQ--EREEQ---QLRPQQRDGKYRWEE---EQLQLEEQEQRLRQERDR 1843
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 46.2 bits (108), Expect = 4e-05
Identities = 37/161 (22%), Positives = 74/161 (45%), Gaps = 24/161 (14%)
Query: 142 LRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRE-----------DIYKRNIELKV 190
L + E L DL++E + + RI LE +++ + ++ + K N E+ V
Sbjct: 548 LTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITV 607
Query: 191 EVESLKRELQDKKQHLDKTWAD-VENLNSQNEAELRRQFEERQQETE------------H 237
VE K EL+ K D W + ++ L Q + E+ + E+ +QE E H
Sbjct: 608 MVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAH 667
Query: 238 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELS 278
+ E+ E ++ L + ++ ++ ++ +++A + ELS
Sbjct: 668 IEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELS 708
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/194 (22%), Positives = 88/194 (45%), Gaps = 15/194 (7%)
Query: 100 SDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFS- 158
++ K + VQ ++ + E + L E+ Q + + +K L L+KE+
Sbjct: 1904 TEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQE 1963
Query: 159 LKLRIYFLEERMQQKYEASREDI-YKRNIELKVEVESLKRELQDKKQHLDKTWADVENLN 217
L++ ++ ++K + +ED+ K N LK + +L K+Q L+ T + N
Sbjct: 1964 LEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKA 2023
Query: 218 SQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLEL 277
+ EAEL E Q+ET + ++ + E+ K A R +++A +E E+
Sbjct: 2024 QEVEAEL---LESHQEETNQL-------LKKIAEKDDDLKRTAKRYEEILDAREE---EM 2070
Query: 278 SEKLKGVTKNWEDV 291
+ K++ + E++
Sbjct: 2071 TAKVRDLQTQLEEL 2084
Score = 38.1 bits (87), Expect = 0.010
Identities = 42/184 (22%), Positives = 88/184 (47%), Gaps = 19/184 (10%)
Query: 137 VQTQALRDFEKHLNDLKK-ENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESL 195
++ ++L + K+ N K E+ L ++ +E ++K +E ++ + L+ +V S+
Sbjct: 1539 IEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKE-AEEKILTLENQVYSM 1597
Query: 196 KRELQDKKQHLDKTWADVEN-------LNSQNEAELRRQFEERQQETEHVYELLENKI-- 246
K EL+ KK+ L+ V++ L + E+E + E +++ E ++ ++
Sbjct: 1598 KAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLS 1657
Query: 247 QLLQEESRLAKNEAARMA----ALVEAEKECNLELSEKLKGVTKNWED---VPGDQVKPD 299
Q+ ++E + K + ++ L E E+E ++ L EKLK V + + VP
Sbjct: 1658 QMEEKEEQYKKGTESHLSELNTKLQEREREVHI-LEEKLKSVESSQSETLIVPRSAKNVA 1716
Query: 300 QYTE 303
YTE
Sbjct: 1717 AYTE 1720
Score = 37.7 bits (86), Expect = 0.013
Identities = 23/116 (19%), Positives = 61/116 (52%), Gaps = 1/116 (0%)
Query: 167 EERMQQKYEASREDIYKRNIELKVEVESLKRELQDK-KQHLDKTWADVENLNSQNEAELR 225
EE++ + + +++ ++ EL ++++ +RE Q++ K L+K+ ++ ++ + E +
Sbjct: 475 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 534
Query: 226 RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 281
EE + + + + ENK++ LQ+E+ + + + +E + N S+ L
Sbjct: 535 LALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 590
Score = 37.0 bits (84), Expect = 0.022
Identities = 40/207 (19%), Positives = 86/207 (41%), Gaps = 20/207 (9%)
Query: 83 EDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQAL 142
E D + +H +D K + ++ ++ K+ Q+Y E+ + Q L
Sbjct: 767 ERDKHLKEHQAHVENLEADIKRS----EGELQQASAKLDVFQSYQSATHEQTKAYEEQ-L 821
Query: 143 RDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 202
++ L DL+ E L ++ + EA ++D+ E+++ K ++QD
Sbjct: 822 AQLQQKLLDLETERILLTKQV--------AEVEAQKKDVC-------TELDAHKIQVQDL 866
Query: 203 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 262
Q L+K +++E + E+ +E E ++L K ++ + K E
Sbjct: 867 MQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEI 926
Query: 263 MAALVEAEKECNLELSEKLKGVTKNWE 289
+ + A+++ L+E+ + KN E
Sbjct: 927 LTQKLSAKEDSIHILNEEYETKFKNQE 953
Score = 36.6 bits (83), Expect = 0.029
Identities = 50/239 (20%), Positives = 100/239 (41%), Gaps = 57/239 (23%)
Query: 123 VQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEE---RMQQKYEASRE 179
++ + + EK QT+ L L+++ K L+ + L++ +M+Q+ EA +
Sbjct: 668 IEEMNEKTLEKLDVKQTE-LESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMD 726
Query: 180 D-------------------IYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS-- 218
+ I + LK ++ L+ L+++ +HL + A VENL +
Sbjct: 727 EQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 786
Query: 219 -QNEAELRRQ------FEERQQETEHVYELLENKIQLLQEESRLAKNE---AARMAALVE 268
++E EL++ F+ Q T + E ++ LQ++ + E + A VE
Sbjct: 787 KRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVE 846
Query: 269 AEKE--C--------------------NLELSEKLKGVTKNWEDVPGDQVKPDQYTEAL 305
A+K+ C N E+ +K+K +T+ +E D K + T+ +
Sbjct: 847 AQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905
Score = 31.6 bits (70), Expect = 0.94
Identities = 23/109 (21%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Query: 140 QALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL 199
+ L+ H+N L ++ LK + LE + + + + + ++ +ELK+ E KR++
Sbjct: 1113 EQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTF-LQEQLVELKMLAEEDKRKV 1171
Query: 200 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQL 248
+ L T + ++L S +E + + E++ E + + E L ++ +
Sbjct: 1172 SELTSKLKTTDEEFQSLKSSHE-KSNKSLEDKSLEFKKLSEELAIQLDI 1219
Score = 29.6 bits (65), Expect = 3.6
Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 36/139 (25%)
Query: 188 LKVEVESLKRELQDKKQHLDKT--------------WADVENLNSQNE-------AELRR 226
L E E+L+ +L ++ Q L+K D +NL Q E AE +R
Sbjct: 312 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR 371
Query: 227 QFEERQQETEHVYELLENKIQLLQ---EESRLAKNEAARMA------------ALVEAEK 271
Q E + E L ++I+ + EE R K ++ R A EA +
Sbjct: 372 QMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARR 431
Query: 272 ECNLELSEKLKGVTKNWED 290
+ E+ E++K + K E+
Sbjct: 432 KLKAEMDEQIKTIEKTSEE 450
Score = 29.3 bits (64), Expect = 4.7
Identities = 31/152 (20%), Positives = 72/152 (47%), Gaps = 24/152 (15%)
Query: 171 QQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVEN-------LNSQNEAE 223
++ E+ E + + +K +E+L++ ++ ++ L + +++ L S+ EA
Sbjct: 261 EENPESDGEPVVEDGTSVKT-LETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEA- 318
Query: 224 LRRQFEERQQETEHVYEL--------------LENKIQLLQEESRLAKNEAAR-MAALVE 268
L+ Q +ER QE E + +L +N I+ L+++ + E R M +E
Sbjct: 319 LQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 269 AEKECNLELSEKLKGVTKNWEDVPGDQVKPDQ 300
++E +L ++K +T E++ + K ++
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELREQKEKSER 410
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 45.8 bits (107), Expect = 5e-05
Identities = 48/201 (23%), Positives = 88/201 (43%), Gaps = 30/201 (14%)
Query: 127 SLRAFEKPPQVQTQALRDFEKHLNDLKKENFSL-KLRIYFLEERMQQKYEASREDIYKRN 185
+L+ +K Q T L+D + HL + N L K + F E Q EA RE + +
Sbjct: 1424 ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK 1483
Query: 186 IE-----LKVEVESLKRELQDK-------KQHLDKTWADVENLNSQN------------- 220
++ L E SLK++L++K Q + A++++++SQ
Sbjct: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQ 1543
Query: 221 ----EAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 276
EA+++ Q EE ++ + L + K++L E R+ + + M + E +E
Sbjct: 1544 LRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQS 1603
Query: 277 LSEKLKGVTKNWEDVPGDQVK 297
+KLK + E+ D+ K
Sbjct: 1604 CQKKLKQMEVQLEEEYEDKQK 1624
Score = 39.3 bits (90), Expect = 0.004
Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 30/160 (18%)
Query: 142 LRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVE-------- 193
L + K +L+++ +L+ ++ FLE+ M K SR++ R +E ++E E
Sbjct: 1783 LEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLE 1842
Query: 194 ----SLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEE-----------------RQ 232
LK ++ + D+ A EN + L+RQ + ++
Sbjct: 1843 SLASRLKENMEKLTEERDQRIA-AENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
Query: 233 QETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 272
E E E LE Q LQ + +LA + A +E E E
Sbjct: 1902 HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEME 1941
Score = 34.7 bits (78), Expect = 0.11
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 18/160 (11%)
Query: 128 LRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRE-DIYKRNI 186
LRA ++ ++QTQ + LKK+ +++ + +E R+ + E + E D
Sbjct: 1320 LRAEKEMKELQTQ--------YDALKKQMEVMEMEV--MEARLIRAAEINGEVDDDDAGG 1369
Query: 187 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQ---QETEHVYELLE 243
E +++ E RE+ K+ L + + D + QN+ +L R+ + Q +E++ + L+
Sbjct: 1370 EWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLK 1429
Query: 244 NKIQLLQEESRLAK----NEAARMAALVEAEKECNLELSE 279
K Q L E + K + R L + ++ + ELS+
Sbjct: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQ 1469
Score = 32.7 bits (73), Expect = 0.42
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 18/114 (15%)
Query: 179 EDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEA-------------ELR 225
+DI K L+ ++ L+RE + + L++ D+ L +++A +L+
Sbjct: 1721 DDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQ 1780
Query: 226 RQFEE---RQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 276
Q EE +QE + + L+++++ L E+S + K+ +R A + E E LE
Sbjct: 1781 AQLEEANKEKQELQEKLQALQSQVEFL-EQSMVDKSLVSRQEAKIR-ELETRLE 1832
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 45.8 bits (107), Expect = 5e-05
Identities = 48/201 (23%), Positives = 88/201 (43%), Gaps = 30/201 (14%)
Query: 127 SLRAFEKPPQVQTQALRDFEKHLNDLKKENFSL-KLRIYFLEERMQQKYEASREDIYKRN 185
+L+ +K Q T L+D + HL + N L K + F E Q EA RE + +
Sbjct: 1424 ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK 1483
Query: 186 IE-----LKVEVESLKRELQDK-------KQHLDKTWADVENLNSQN------------- 220
++ L E SLK++L++K Q + A++++++SQ
Sbjct: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQ 1543
Query: 221 ----EAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 276
EA+++ Q EE ++ + L + K++L E R+ + + M + E +E
Sbjct: 1544 LRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQS 1603
Query: 277 LSEKLKGVTKNWEDVPGDQVK 297
+KLK + E+ D+ K
Sbjct: 1604 CQKKLKQMEVQLEEEYEDKQK 1624
Score = 39.7 bits (91), Expect = 0.003
Identities = 41/179 (22%), Positives = 74/179 (41%), Gaps = 32/179 (17%)
Query: 142 LRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVE-------- 193
L + K +L+++ +L+ ++ FLE+ M K SR++ R +E ++E E
Sbjct: 1783 LEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLE 1842
Query: 194 ----SLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEE-----------------RQ 232
LK ++ + D+ A EN + L+RQ + ++
Sbjct: 1843 SLASRLKENMEKLTEERDQRIA-AENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
Query: 233 QETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKEC--NLELSEKLKGVTKNWE 289
E E E LE Q LQ + +LA + A +E E E N +L L+ + ++
Sbjct: 1902 HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQ 1960
Score = 34.7 bits (78), Expect = 0.11
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 18/160 (11%)
Query: 128 LRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRE-DIYKRNI 186
LRA ++ ++QTQ + LKK+ +++ + +E R+ + E + E D
Sbjct: 1320 LRAEKEMKELQTQ--------YDALKKQMEVMEMEV--MEARLIRAAEINGEVDDDDAGG 1369
Query: 187 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQ---QETEHVYELLE 243
E +++ E RE+ K+ L + + D + QN+ +L R+ + Q +E++ + L+
Sbjct: 1370 EWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLK 1429
Query: 244 NKIQLLQEESRLAK----NEAARMAALVEAEKECNLELSE 279
K Q L E + K + R L + ++ + ELS+
Sbjct: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQ 1469
Score = 32.7 bits (73), Expect = 0.42
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 18/114 (15%)
Query: 179 EDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEA-------------ELR 225
+DI K L+ ++ L+RE + + L++ D+ L +++A +L+
Sbjct: 1721 DDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQ 1780
Query: 226 RQFEE---RQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 276
Q EE +QE + + L+++++ L E+S + K+ +R A + E E LE
Sbjct: 1781 AQLEEANKEKQELQEKLQALQSQVEFL-EQSMVDKSLVSRQEAKIR-ELETRLE 1832
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 45.4 bits (106), Expect = 6e-05
Identities = 49/226 (21%), Positives = 97/226 (42%), Gaps = 26/226 (11%)
Query: 99 LSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFS 158
L +DR +QSQ R+ E++ + +R E+ Q + + L + K LN+ KE+ +
Sbjct: 99 LEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQ-ELEYLTEDVKRLNEKLKESNT 157
Query: 159 LK--------------LRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQ 204
K + + + E+R++Q+ E N ELK + + L ++K
Sbjct: 158 TKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGN 217
Query: 205 HLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMA 264
+ + ++EN + + L Q + EH+ + +E+ + L+E AK + A M
Sbjct: 218 EILELKCNLEN-KKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE----AKEQQASME 272
Query: 265 ALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 310
E +++LS K + + K ++ T A+ + K
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADD------SEAKSNELTRAVEELHK 312
Score = 32.3 bits (72), Expect = 0.55
Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 20/151 (13%)
Query: 142 LRDFEKHLNDLKKENFS-------LKLRIYFLEERMQQKYEASREDIYKRNIELKV---- 190
LR E+ +NDLK+ + + + LEE + ++ + + E ++NIE+++
Sbjct: 941 LRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEE--VRKNIEVRLKESA 998
Query: 191 ----EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKI 246
++E E++ +KQ L Q +EL++ Q E V E L+
Sbjct: 999 EFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNE---VQEALQRAS 1055
Query: 247 QLLQEESRLAKNEAARMAALVEAEKECNLEL 277
L E + ++ + VEA+ + EL
Sbjct: 1056 TALSNEQQARRDCQEQAKIAVEAQNKYEREL 1086
Score = 28.9 bits (63), Expect = 6.1
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 8/84 (9%)
Query: 197 RELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLA 256
+E+Q+ K+ L++ ++L SQ E L++ E++ E + L E +QL E SRL
Sbjct: 1474 QEMQELKETLNQAETKSKSLESQVE-NLQKTLSEKETEARN---LQEQTVQLQSELSRLR 1529
Query: 257 KNEAARMAALVEAEKECNLELSEK 280
++ R E++ +++EK
Sbjct: 1530 QDLQDR----TTQEEQLRQQITEK 1549
Score = 28.9 bits (63), Expect = 6.1
Identities = 35/173 (20%), Positives = 73/173 (42%), Gaps = 12/173 (6%)
Query: 99 LSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFS 158
L+ + + ++SQ+ + + +T + E+ Q+Q++ R + L D +
Sbjct: 1483 LNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSR-LRQDLQDRTTQEEQ 1541
Query: 159 LKLRIYFLEERMQQKYEASR----------EDIYKRNIELKVEVESLKRELQDKKQHLDK 208
L+ +I EE+ ++ A++ + + K N ELK +L ++ + +
Sbjct: 1542 LRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITA 1601
Query: 209 TWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAA 261
+ E S+ E EL R+ +ER E + NK+ Q + L A+
Sbjct: 1602 LKSQYEGRISRLEREL-REHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPAS 1653
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 45.4 bits (106), Expect = 6e-05
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Query: 149 LNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDK 208
L + ++EN SLK ++ LE +Q E ++E + K EVE+LK ++++ + L
Sbjct: 2142 LKERERENDSLKDKVENLERELQMS-EENQELVILDAENSKAEVETLKTQIEEMARSLKV 2200
Query: 209 TWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVE 268
D+ L S+ E L +Q +E+Q + + +LL + LL+E+ + VE
Sbjct: 2201 FELDLVTLRSEKE-NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVE 2259
Query: 269 AEKECNLELSEKLKGVTKNWE 289
+ EL+E + + + E
Sbjct: 2260 MLQNQLKELNEAVAALCGDQE 2280
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/130 (26%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 142 LRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 201
L ++ ++ L++ L++RI +E+ Q ++ + N LK +VE+L+RELQ
Sbjct: 2107 LSSTQEEVHQLRRGIEKLRVRIE-ADEKKQLHIAEKLKERERENDSLKDKVENLERELQM 2165
Query: 202 KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAA 261
+++ + D EN ++ E L+ Q EE + + V+EL + + L E+ L K
Sbjct: 2166 SEENQELVILDAENSKAEVET-LKTQIEEMARSLK-VFEL--DLVTLRSEKENLTKQIQE 2221
Query: 262 RMAALVEAEK 271
+ L E +K
Sbjct: 2222 KQGQLSELDK 2231
Score = 37.0 bits (84), Expect = 0.022
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 25/142 (17%)
Query: 153 KKENFSLKLRIYFLEERMQ--QKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDK-T 209
K++N L+ LE+++Q Q AS +D + L+ ++L+ EL+ K +DK +
Sbjct: 2552 KEQNLELRNLTVELEQKIQVLQSKNASLQDTLE---VLQSSYKNLENELELTK--MDKMS 2606
Query: 210 WADVENLNSQNEAELRRQFEERQQETEHVYELLENK-------IQLLQEESRLAKNEAAR 262
+ + N + E EL+R+ E Q+T + E L + +QLL EE + +K++
Sbjct: 2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQL-- 2664
Query: 263 MAALVEAEKECNLELSEKLKGV 284
KE LE SE K +
Sbjct: 2665 --------KELTLENSELKKSL 2678
Score = 35.4 bits (80), Expect = 0.065
Identities = 34/143 (23%), Positives = 71/143 (49%), Gaps = 7/143 (4%)
Query: 140 QALRDFEKHLNDLKKENFSLKLRI-YFLEERMQQKYEASREDIYKRNIELKVEVESLKRE 198
+A + EK + +LKKEN L ++ YF + + + ++E+ + +S + +
Sbjct: 1823 EACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHAD-KSSRED 1881
Query: 199 LQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESR-LAK 257
+ D ++ +W + L+ +NE R + E+ E E +Y LE ++++Q E L K
Sbjct: 1882 IGDNVAKVNDSWKE-RFLDVENELS-RIRSEKASIEHEALY--LEADLEVVQTEKLCLEK 1937
Query: 258 NEAARMAALVEAEKECNLELSEK 280
+ + +V E+E ++ SE+
Sbjct: 1938 DNENKQKVIVCLEEELSVVTSER 1960
Score = 35.0 bits (79), Expect = 0.085
Identities = 36/146 (24%), Positives = 70/146 (47%), Gaps = 19/146 (13%)
Query: 152 LKKENFSLKLRIYFLEERM------QQKYEASREDIYKRNIELKVEVESLKRELQDKKQH 205
L+K+N + + I LEE + + + + + K+ L + L ++++K Q
Sbjct: 1935 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTAL----DQLSEKMKEKTQE 1990
Query: 206 LDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN------KIQLLQEESR---LA 256
L+ ++ + EAE++ + E Q + V ELL++ K+Q L+++S+ L
Sbjct: 1991 LESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2050
Query: 257 KNEAARMAALVEAEKECNLELSEKLK 282
K E A + EKE ++ SE L+
Sbjct: 2051 KCELENQIAQLNKEKELLVKESESLQ 2076
Score = 33.9 bits (76), Expect = 0.19
Identities = 31/120 (25%), Positives = 62/120 (51%), Gaps = 13/120 (10%)
Query: 169 RMQQKYEAS--REDIYKRNIE-LKVEVESLKRELQDKKQHLDKTWADVENLN-----SQN 220
R +Q ++AS +E+ +R++E +K E LK + K + + A+++N+ SQN
Sbjct: 462 RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQN 521
Query: 221 EAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEK 280
AE + + + E + L+ KI Q+E+ L + A +E +++C+ +L +K
Sbjct: 522 FAE---EMKAKNTSQETMLRDLQEKIN--QQENSLTLEKLKLAVADLEKQRDCSQDLLKK 576
Score = 33.1 bits (74), Expect = 0.32
Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 18/148 (12%)
Query: 153 KKENFSLKLRIYFLEE-RMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWA 211
K++N S ++ LE+ ++ Q + ++ + I L+ V L +E++D KQ L+K
Sbjct: 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNY----IVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Query: 212 DVENLNSQ-----------NEAELRRQ-FEERQQETEHVYELLENKIQLLQ-EESRLAKN 258
++ L +Q ++ E Q ++E+ E ++ LE KIQ+LQ + + L
Sbjct: 2523 EISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDT 2582
Query: 259 EAARMAALVEAEKECNLELSEKLKGVTK 286
++ E E L +K+ V K
Sbjct: 2583 LEVLQSSYKNLENELELTKMDKMSFVEK 2610
Score = 32.7 bits (73), Expect = 0.42
Identities = 30/157 (19%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
Query: 126 YSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRN 185
+ ++ E + +T+ L+ +++L K+ L+ ++ LE+ Q ++ ++ +
Sbjct: 2000 HCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKD-SQALSLTKCELENQI 2058
Query: 186 IELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENK 245
+L E E L +E + + L ++ + N++ EA L + E +
Sbjct: 2059 AQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGE------------FALR 2106
Query: 246 IQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 282
+ QEE + ++ +EA+++ L ++EKLK
Sbjct: 2107 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLK 2143
Score = 31.6 bits (70), Expect = 0.94
Identities = 40/181 (22%), Positives = 66/181 (36%), Gaps = 40/181 (22%)
Query: 154 KENFSLKLRIYFLEERMQQKY-------EASREDIYKRNIELKVEVESLKRELQDKKQHL 206
KE+ ++ F EER Q +A R ++ K E LK+E+ K+
Sbjct: 1080 KEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQ 1139
Query: 207 DKTWADVENLNSQNE-----------------AELRRQFEERQQETEHV----------- 238
+K +V +L +NE +R +ER+ E
Sbjct: 1140 NKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVK 1199
Query: 239 -YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG--VTKNWEDVPGDQ 295
L QL+Q E+ L E + E EKEC + ++G T N +D+ +
Sbjct: 1200 EISLDSYNAQLVQLEAMLRNKELKLQES--EKEKECLQHELQTIRGDLETSNLQDMQSQE 1257
Query: 296 V 296
+
Sbjct: 1258 I 1258
Score = 30.8 bits (68), Expect = 1.6
Identities = 25/112 (22%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 166 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR 225
LE+++++K + +E++ ++ ++L +E K L + +N+++ +AEL
Sbjct: 385 LEQKIKEKEKEFQEELSRQQRSF----QTLDQECIQMKARLTQELQQAKNMHNVLQAELD 440
Query: 226 RQFEERQQETEHVYELLENKIQLLQ--EESRLAKNEAARMAALVEAEKECNL 275
+ +QQ ++ E + + Q + S++ +NE R ++ E +KE NL
Sbjct: 441 KLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR--SMEEMKKENNL 490
Score = 30.4 bits (67), Expect = 2.1
Identities = 40/177 (22%), Positives = 80/177 (45%), Gaps = 22/177 (12%)
Query: 97 AFLSDTKDRGPPVQSQIWRSGEKVPFVQTYS-LRAFEKPPQVQTQALRDFEKHLNDLKKE 155
+F+++T R +Q S + +T S L EK Q+ + + + +LKK
Sbjct: 876 SFVAETSQRISKLQEDT--SAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKS 933
Query: 156 NFSLK-----LRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL-----QDKKQH 205
N L+ L++ +++K +S + KR IE + +E+ Q+K
Sbjct: 934 NHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNL 993
Query: 206 LDKT--WADVENLNSQNEAELRRQFEE-------RQQETEHVYELLENKIQLLQEES 253
+ K+ +A+ + ++ +EL Q+++ R +ET + YE L K + QE++
Sbjct: 994 IQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKN 1050
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 45.4 bits (106), Expect = 6e-05
Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 6/150 (4%)
Query: 127 SLRAFEKPPQVQTQALR-DFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRN 185
+LR E+ Q++ Q + D + L ++K + ++ ER++Q E ++ I ++
Sbjct: 544 NLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 603
Query: 186 IELKVEVESLKREL----QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 241
++ + E K E + KK+ K +VE Q E R ++ ++++E EL
Sbjct: 604 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 663
Query: 242 LENKIQLLQEESRLAKNEAARMAALVEAEK 271
L+ K + QE R A EA R+A E E+
Sbjct: 664 LQKKKEEEQERLRKAA-EAKRLAEQREQER 692
Score = 36.6 bits (83), Expect = 0.029
Identities = 39/165 (23%), Positives = 75/165 (45%), Gaps = 19/165 (11%)
Query: 132 EKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVE 191
+K Q+ + + E+ L + K + + ++ +E R +Q+ EA R ++ E +
Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660
Query: 192 VESLKRELQDKKQHLDKTWADVENLNSQNEAELR--------------RQFEERQQETEH 237
E L+++ +++++ L K A+ + L Q E E R R+ E R+QE +
Sbjct: 661 QELLQKKKEEEQERLRKA-AEAKRLAEQREQERREQERREQERREQERREQERREQERQL 719
Query: 238 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 282
+ + + LQ E L + E AL +++ EL EK K
Sbjct: 720 AEQERRREQERLQAERELQERE----KALRLQKEQLQRELEEKKK 760
Score = 30.0 bits (66), Expect = 2.7
Identities = 16/57 (28%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 169 RMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR 225
R Q++ +A RE + +R L+++ E L+REL++KK+ ++ L + E + +
Sbjct: 726 REQERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 45.4 bits (106), Expect = 6e-05
Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 6/150 (4%)
Query: 127 SLRAFEKPPQVQTQALR-DFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRN 185
+LR E+ Q++ Q + D + L ++K + ++ ER++Q E ++ I ++
Sbjct: 540 NLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 599
Query: 186 IELKVEVESLKREL----QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 241
++ + E K E + KK+ K +VE Q E R ++ ++++E EL
Sbjct: 600 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 659
Query: 242 LENKIQLLQEESRLAKNEAARMAALVEAEK 271
L+ K + QE R A EA R+A E E+
Sbjct: 660 LQKKKEEEQERLRKAA-EAKRLAEQREQER 688
Score = 36.6 bits (83), Expect = 0.029
Identities = 39/165 (23%), Positives = 75/165 (45%), Gaps = 19/165 (11%)
Query: 132 EKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVE 191
+K Q+ + + E+ L + K + + ++ +E R +Q+ EA R ++ E +
Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656
Query: 192 VESLKRELQDKKQHLDKTWADVENLNSQNEAELR--------------RQFEERQQETEH 237
E L+++ +++++ L K A+ + L Q E E R R+ E R+QE +
Sbjct: 657 QELLQKKKEEEQERLRKA-AEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
Query: 238 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 282
+ + + LQ E L + E AL +++ EL EK K
Sbjct: 716 AEQERRREQERLQAERELQERE----KALRLQKEQLQRELEEKKK 756
Score = 30.0 bits (66), Expect = 2.7
Identities = 16/57 (28%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 169 RMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR 225
R Q++ +A RE + +R L+++ E L+REL++KK+ ++ L + E + +
Sbjct: 722 REQERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
sapiens]
Length = 436
Score = 45.1 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 20/183 (10%)
Query: 127 SLRAFEKPPQVQTQALRDF--------EKHLNDLKKENFSLKLRIYFLEERMQQKYEASR 178
SL +K +++ ++L D EK +NDLK EN +L ++ E++ + + +A+
Sbjct: 235 SLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANL 294
Query: 179 EDIYKRNIELKVEVESLKRELQDKKQHL---DKTWADVENLNSQNEAELRRQFEERQQET 235
++ + + L+ E+ESLK L+ K + L D +E L N A L + + QQE
Sbjct: 295 KN--PQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTA-LVDKLKRFQQEN 351
Query: 236 EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQ 295
E + ++ + + SR E A + +E E + N LS ++ W+ GD
Sbjct: 352 EELKARMDKHMAI----SRQLSTEQAVLQESLEKESKVNKRLS--MENEELLWKLHNGDL 405
Query: 296 VKP 298
P
Sbjct: 406 CSP 408
Score = 34.7 bits (78), Expect = 0.11
Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 47/203 (23%)
Query: 122 FVQTYSLRAFEKPPQVQTQALRDFEKHLNDL---KKENFSLKLRIYF-----------LE 167
FVQ + E+ +++ R++EK L D + E + ++L+ F LE
Sbjct: 158 FVQQHQAEKTERENRLKEFYTREYEK-LRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLE 216
Query: 168 ---------ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS 218
E +++ YEAS +I K + ++E +SL+ L +K++ L+K D+++ N
Sbjct: 217 IEASHSEKLELLKKAYEASLSEIKKGH---EIEKKSLEDLLSEKQESLEKQINDLKSEND 273
Query: 219 QNEAELRRQFEER----------------QQETEHVYELLENKIQLL-QEESRLAKNE-- 259
+L+ + ++R +QE E + +LE K + L Q++ +L K E
Sbjct: 274 ALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKL 333
Query: 260 AARMAALVEAEKECNLELSEKLK 282
ALV+ K E +E+LK
Sbjct: 334 VDNNTALVDKLKRFQQE-NEELK 355
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
Length = 1270
Score = 45.1 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 20/183 (10%)
Query: 127 SLRAFEKPPQVQTQALRDF--------EKHLNDLKKENFSLKLRIYFLEERMQQKYEASR 178
SL +K +++ ++L D EK +NDLK EN +L ++ E++ + + +A+
Sbjct: 1069 SLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANL 1128
Query: 179 EDIYKRNIELKVEVESLKRELQDKKQHL---DKTWADVENLNSQNEAELRRQFEERQQET 235
++ + + L+ E+ESLK L+ K + L D +E L N A L + + QQE
Sbjct: 1129 KN--PQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTA-LVDKLKRFQQEN 1185
Query: 236 EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQ 295
E + ++ + + SR E A + +E E + N LS ++ W+ GD
Sbjct: 1186 EELKARMDKHMAI----SRQLSTEQAVLQESLEKESKVNKRLS--MENEELLWKLHNGDL 1239
Query: 296 VKP 298
P
Sbjct: 1240 CSP 1242
Score = 34.7 bits (78), Expect = 0.11
Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 47/203 (23%)
Query: 122 FVQTYSLRAFEKPPQVQTQALRDFEKHLNDL---KKENFSLKLRIYF-----------LE 167
FVQ + E+ +++ R++EK L D + E + ++L+ F LE
Sbjct: 992 FVQQHQAEKTERENRLKEFYTREYEK-LRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLE 1050
Query: 168 ---------ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS 218
E +++ YEAS +I K + ++E +SL+ L +K++ L+K D+++ N
Sbjct: 1051 IEASHSEKLELLKKAYEASLSEIKKGH---EIEKKSLEDLLSEKQESLEKQINDLKSEND 1107
Query: 219 QNEAELRRQFEER----------------QQETEHVYELLENKIQLL-QEESRLAKNE-- 259
+L+ + ++R +QE E + +LE K + L Q++ +L K E
Sbjct: 1108 ALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKL 1167
Query: 260 AARMAALVEAEKECNLELSEKLK 282
ALV+ K E +E+LK
Sbjct: 1168 VDNNTALVDKLKRFQQE-NEELK 1189
>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
Length = 1216
Score = 45.1 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 20/183 (10%)
Query: 127 SLRAFEKPPQVQTQALRDF--------EKHLNDLKKENFSLKLRIYFLEERMQQKYEASR 178
SL +K +++ ++L D EK +NDLK EN +L ++ E++ + + +A+
Sbjct: 1015 SLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANL 1074
Query: 179 EDIYKRNIELKVEVESLKRELQDKKQHL---DKTWADVENLNSQNEAELRRQFEERQQET 235
++ + + L+ E+ESLK L+ K + L D +E L N A L + + QQE
Sbjct: 1075 KN--PQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTA-LVDKLKRFQQEN 1131
Query: 236 EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQ 295
E + ++ + + SR E A + +E E + N LS ++ W+ GD
Sbjct: 1132 EELKARMDKHMAI----SRQLSTEQAVLQESLEKESKVNKRLS--MENEELLWKLHNGDL 1185
Query: 296 VKP 298
P
Sbjct: 1186 CSP 1188
Score = 34.7 bits (78), Expect = 0.11
Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 47/203 (23%)
Query: 122 FVQTYSLRAFEKPPQVQTQALRDFEKHLNDL---KKENFSLKLRIYF-----------LE 167
FVQ + E+ +++ R++EK L D + E + ++L+ F LE
Sbjct: 938 FVQQHQAEKTERENRLKEFYTREYEK-LRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLE 996
Query: 168 ---------ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS 218
E +++ YEAS +I K + ++E +SL+ L +K++ L+K D+++ N
Sbjct: 997 IEASHSEKLELLKKAYEASLSEIKKGH---EIEKKSLEDLLSEKQESLEKQINDLKSEND 1053
Query: 219 QNEAELRRQFEER----------------QQETEHVYELLENKIQLL-QEESRLAKNE-- 259
+L+ + ++R +QE E + +LE K + L Q++ +L K E
Sbjct: 1054 ALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKL 1113
Query: 260 AARMAALVEAEKECNLELSEKLK 282
ALV+ K E +E+LK
Sbjct: 1114 VDNNTALVDKLKRFQQE-NEELK 1135
>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
sapiens]
Length = 517
Score = 45.1 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 20/183 (10%)
Query: 127 SLRAFEKPPQVQTQALRDF--------EKHLNDLKKENFSLKLRIYFLEERMQQKYEASR 178
SL +K +++ ++L D EK +NDLK EN +L ++ E++ + + +A+
Sbjct: 316 SLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANL 375
Query: 179 EDIYKRNIELKVEVESLKRELQDKKQHL---DKTWADVENLNSQNEAELRRQFEERQQET 235
++ + + L+ E+ESLK L+ K + L D +E L N A L + + QQE
Sbjct: 376 KN--PQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTA-LVDKLKRFQQEN 432
Query: 236 EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQ 295
E + ++ + + SR E A + +E E + N LS ++ W+ GD
Sbjct: 433 EELKARMDKHMAI----SRQLSTEQAVLQESLEKESKVNKRLS--MENEELLWKLHNGDL 486
Query: 296 VKP 298
P
Sbjct: 487 CSP 489
Score = 34.7 bits (78), Expect = 0.11
Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 47/203 (23%)
Query: 122 FVQTYSLRAFEKPPQVQTQALRDFEKHLNDL---KKENFSLKLRIYF-----------LE 167
FVQ + E+ +++ R++EK L D + E + ++L+ F LE
Sbjct: 239 FVQQHQAEKTERENRLKEFYTREYEK-LRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLE 297
Query: 168 ---------ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS 218
E +++ YEAS +I K + ++E +SL+ L +K++ L+K D+++ N
Sbjct: 298 IEASHSEKLELLKKAYEASLSEIKKGH---EIEKKSLEDLLSEKQESLEKQINDLKSEND 354
Query: 219 QNEAELRRQFEER----------------QQETEHVYELLENKIQLL-QEESRLAKNE-- 259
+L+ + ++R +QE E + +LE K + L Q++ +L K E
Sbjct: 355 ALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKL 414
Query: 260 AARMAALVEAEKECNLELSEKLK 282
ALV+ K E +E+LK
Sbjct: 415 VDNNTALVDKLKRFQQE-NEELK 436
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 45.1 bits (105), Expect = 8e-05
Identities = 44/166 (26%), Positives = 79/166 (47%), Gaps = 22/166 (13%)
Query: 109 VQSQIWRSGEKVPFVQTYSLRAFEKPPQVQT--QALR-DFEKHLNDLKKENFSLKLRIYF 165
+Q+Q+ R + ++T S + Q+Q+ + L+ D + + DL++E L ++
Sbjct: 513 LQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWS 572
Query: 166 LEERMQQKYEASREDIYKRN--------------IELKVEVESLKRELQ---DKKQHLDK 208
L ER Q EA +D+ K N +L+ E L R+L+ +K + +K
Sbjct: 573 LRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERAEK 632
Query: 209 TWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESR 254
+++ L +N L R+ + TE V E LE++ Q LQ E+R
Sbjct: 633 LERELQRLQEEN-GRLARKVTSLETATEKV-EALEHESQGLQLENR 676
Score = 34.7 bits (78), Expect = 0.11
Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 26/174 (14%)
Query: 126 YSLRAFEKPPQVQTQALRDFEKHLND--------LKKENFSLKLRIYFLEERMQQKYEAS 177
+ L K + + + F LN+ L+KEN SL+ I L + E+
Sbjct: 434 WELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESG 493
Query: 178 RE--DIYKRNIELKVEVESLKRELQDKKQH-------LDKTWADVENLNSQNE---AELR 225
+ ++ K N +L ++E L+ +L+ +KQ ++ + E L S E A+
Sbjct: 494 LKCGELEKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKA 553
Query: 226 RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSE 279
RQ ++ +QE +H L + L+E S+++ ARM + + K + ++E
Sbjct: 554 RQIKDLEQEKDH----LNRAMWSLRERSQVSSE--ARMKDVEKENKALHQTVTE 601
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/223 (23%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Query: 92 TSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLND 151
T +T A + + V ++ + +V +Q +K ++Q Q L + K +
Sbjct: 624 TENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQ-LTESLKETDL 682
Query: 152 LKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD---KKQHLDK 208
L+ + ++ ++ L+E +Q + + R +L+++V SL+ EL D +K+ L+K
Sbjct: 683 LRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRK-QLELKVTSLEEELTDLRVEKESLEK 741
Query: 209 TWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNE-AARMAALV 267
++ + A+ R Q EE E Y+ +K++ L +++R++ ++ AA +LV
Sbjct: 742 NLSE----RKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLV 797
Query: 268 EAEKECNLELS-EKLKGVTKNWEDVPGDQVKPDQYTEALAQRD 309
+AE + E E L K+ QY E AQRD
Sbjct: 798 QAELQTQWEAKCEHLLASAKD--------EHLQQYQEVCAQRD 832
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,660,936
Number of Sequences: 37866
Number of extensions: 612090
Number of successful extensions: 6210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 662
Number of HSP's that attempted gapping in prelim test: 4297
Number of HSP's gapped (non-prelim): 2129
length of query: 310
length of database: 18,247,518
effective HSP length: 102
effective length of query: 208
effective length of database: 14,385,186
effective search space: 2992118688
effective search space used: 2992118688
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.