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Search of human proteins with 50557648
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50557648 zinc finger, FYVE domain containing 27 isoform c
[Homo sapiens]
(404 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Ho... 823 0.0
gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Ho... 816 0.0
gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Ho... 810 0.0
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 58 2e-08
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 53 6e-07
gi|217272865 myotubularin related protein 4 [Homo sapiens] 53 6e-07
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 52 7e-07
gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens] 50 3e-06
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 50 4e-06
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 49 6e-06
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 49 1e-05
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 48 2e-05
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 48 2e-05
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 47 3e-05
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 47 3e-05
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 47 3e-05
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 46 5e-05
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 46 5e-05
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 46 5e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 45 2e-04
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 45 2e-04
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 45 2e-04
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 43 6e-04
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 40 0.003
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 38 0.014
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 38 0.014
gi|217035164 coiled-coil domain containing 27 [Homo sapiens] 37 0.042
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 37 0.042
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 37 0.042
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 36 0.054
>gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Homo
sapiens]
Length = 404
Score = 823 bits (2127), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGAPC 300
HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGAPC
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGAPC 300
Query: 301 PAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCS 360
PAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCS
Sbjct: 301 PAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCS 360
Query: 361 NCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 404
NCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 361 NCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 404
>gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Homo
sapiens]
Length = 411
Score = 816 bits (2109), Expect = 0.0
Identities = 404/411 (98%), Positives = 404/411 (98%), Gaps = 7/411 (1%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIE-------E 293
HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIE E
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLE 300
Query: 294 DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL 353
DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL
Sbjct: 301 DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL 360
Query: 354 KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 404
KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 361 KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 411
>gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Homo
sapiens]
Length = 416
Score = 810 bits (2093), Expect = 0.0
Identities = 404/416 (97%), Positives = 404/416 (97%), Gaps = 12/416 (2%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTE-----DLTPGSVEEAEEAEPDEEFKDAIE--- 292
HAFESPPPPDVGGKDGLMDSTPALTPTE DLTPGSVEEAEEAEPDEEFKDAIE
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETH 300
Query: 293 ----EDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 348
EDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA
Sbjct: 301 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 360
Query: 349 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 404
TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 361 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 416
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 27/143 (18%)
Query: 281 AEPDEEFKDAIEEDDEGAPCPA-EDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNN 339
+ PD+ + +++D + L ++G + E L+ +V L RL +Y T++
Sbjct: 1005 SSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSS 1064
Query: 340 ------FGN--------------CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSS 379
FG+ C C + F + ++ C NCGN FCS CC+ KVP S
Sbjct: 1065 LHFNGDFGDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPS 1124
Query: 380 MGATAPEAQRETVFVCASCNQTL 402
P VC SC +L
Sbjct: 1125 QQLFEPSR------VCKSCYSSL 1141
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 52.8 bits (125), Expect = 6e-07
Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Query: 277 EAEEAEPDEEFKDAIEEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYP 336
E +P+ + K+ + + + A ++ AL LS +E+ E + P
Sbjct: 758 EVMATKPETDDKEKLRKVTQTLRSAALEDCALCQET-LSSSELAAKTRDGDFEDPPEWVP 816
Query: 337 TNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCA 396
G CT C A F+V++++ C +CG FCSRC S P G P V VC
Sbjct: 817 DEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKP------VRVCT 870
Query: 397 SC 398
C
Sbjct: 871 HC 872
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 52.8 bits (125), Expect = 6e-07
Identities = 36/122 (29%), Positives = 51/122 (41%), Gaps = 10/122 (8%)
Query: 278 AEEAEPDEEFKDAIEEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPT 337
A AEP +++D E ED + LS E V + + + P
Sbjct: 1057 APPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLS--EASWEPVDKKETEVTRWVPD 1114
Query: 338 NNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQ-RETVFVCA 396
+ +C C F + K+R C NCGN FC+ CC K+P P+ Q + V VC
Sbjct: 1115 HMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLP-------IPDQQLYDPVLVCN 1167
Query: 397 SC 398
SC
Sbjct: 1168 SC 1169
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 52.4 bits (124), Expect = 7e-07
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 317 NEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVP 376
+E +V + + + P + +C C + F + ++ C NCGN FCS CC+ KVP
Sbjct: 1099 SEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVP 1158
Query: 377 KSSMGATAPEAQRETVFVCASCNQTL 402
S P VC SC +L
Sbjct: 1159 VPSQQLFEPSR------VCKSCYSSL 1178
>gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens]
Length = 471
Score = 50.4 bits (119), Expect = 3e-06
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 343 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 402
C GC+ F++ KK C NCG +FCS C SF A P VC C++ L
Sbjct: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSF-------SAAVPRTGNTQQKVCKQCHEVL 132
Query: 403 SK 404
++
Sbjct: 133 TR 134
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 50.1 bits (118), Expect = 4e-06
Identities = 38/152 (25%), Positives = 60/152 (39%), Gaps = 36/152 (23%)
Query: 281 AEPDEEFKDAIEEDDEGAPCPA-EDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNN 339
+ PD+ + +++D + L ++G + E L+ +V L RL +Y T++
Sbjct: 1005 SSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSS 1064
Query: 340 ------FGN--------------CTGCSATFSVLKKRRSCS---------NCGNSFCSRC 370
FG+ C C + F + ++ C NCGN FCS C
Sbjct: 1065 LHFNGDFGDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSC 1124
Query: 371 CSFKVPKSSMGATAPEAQRETVFVCASCNQTL 402
C+ KVP S P VC SC +L
Sbjct: 1125 CNQKVPVPSQQLFEPSR------VCKSCYSSL 1150
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 49.3 bits (116), Expect = 6e-06
Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 6/63 (9%)
Query: 336 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 395
P C C A F L ++ C CG FC RCCS KVP M P Q C
Sbjct: 43 PDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQ------C 96
Query: 396 ASC 398
A C
Sbjct: 97 AEC 99
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 48.5 bits (114), Expect = 1e-05
Identities = 19/48 (39%), Positives = 26/48 (54%)
Query: 336 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGAT 383
P + C CS F+ ++R C CG FCSRCC+ ++P MG T
Sbjct: 157 PDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYT 204
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 342 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 401
+C+GCS FS+ ++R C NCG FC +C F+ + ++P V VC +C
Sbjct: 214 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSP------VRVCQNCYYN 267
Query: 402 L 402
L
Sbjct: 268 L 268
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 342 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 401
+C+GCS FS+ ++R C NCG FC +C F+ + ++P V VC +C
Sbjct: 3459 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSP------VRVCQNCYYN 3512
Query: 402 L 402
L
Sbjct: 3513 L 3513
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 336 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 395
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 396 ASCNQTL 402
C+ L
Sbjct: 751 VICHSVL 757
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 336 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 395
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 396 ASCNQTL 402
C+ L
Sbjct: 751 VICHSVL 757
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 336 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 395
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 396 ASCNQTL 402
C+ L
Sbjct: 751 VICHSVL 757
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Query: 285 EEFKDAIEEDDEGAPCPAEDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFG 341
+E ++ +E E E E ALQ+ G LS++++ + + + L+ +
Sbjct: 479 KELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEAT 538
Query: 342 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 401
+C C FS+ +++ C NCG+ FC+ C S ++ A + + V VC SC+
Sbjct: 539 HCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTL 590
Query: 402 L 402
L
Sbjct: 591 L 591
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Query: 285 EEFKDAIEEDDEGAPCPAEDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFG 341
+E ++ +E E E E ALQ+ G LS++++ + + + L+ +
Sbjct: 479 KELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEAT 538
Query: 342 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 401
+C C FS+ +++ C NCG+ FC+ C S ++ A + + V VC SC+
Sbjct: 539 HCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTL 590
Query: 402 L 402
L
Sbjct: 591 L 591
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Query: 285 EEFKDAIEEDDEGAPCPAEDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFG 341
+E ++ +E E E E ALQ+ G LS++++ + + + L+ +
Sbjct: 587 KELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEAT 646
Query: 342 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 401
+C C FS+ +++ C NCG+ FC+ C S ++ A + + V VC SC+
Sbjct: 647 HCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTL 698
Query: 402 L 402
L
Sbjct: 699 L 699
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 8/67 (11%)
Query: 332 RKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRET 391
RK N NC C FSV +R C CGN FC+ C S+ A P + ++
Sbjct: 1347 RKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAEC-------SAKNALTP-SSKKP 1398
Query: 392 VFVCASC 398
V VC +C
Sbjct: 1399 VRVCDAC 1405
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 336 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 395
P + NC C F+ K+R C CG FC CC+ K + A VC
Sbjct: 746 PDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEAR--------VC 797
Query: 396 ASCNQTLSK 404
C +T+SK
Sbjct: 798 VVCYETISK 806
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 336 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 395
P + NC C F+ K+R C CG FC CC+ K + A VC
Sbjct: 746 PDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEAR--------VC 797
Query: 396 ASCNQTLSK 404
C +T+SK
Sbjct: 798 VVCYETISK 806
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 42.7 bits (99), Expect = 6e-04
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 11/121 (9%)
Query: 285 EEFKDAIEEDDEGAPCPAEDELALQDNGF-LSKNEVLRSKVSRLTERLRKRY--PTNNFG 341
+EF + +E+ + E E ALQ+ G LS++++ + + L+
Sbjct: 520 KEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEAT 579
Query: 342 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 401
+C C FS+ K++ C NCG FC+ C ++P S +P+ R VC SC+
Sbjct: 580 HCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPS----SPKPVR----VCDSCHAL 631
Query: 402 L 402
L
Sbjct: 632 L 632
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 326 RLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAP 385
RL + L K P + C C+A F V ++ C +CG C +C + ++P P
Sbjct: 1094 RLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKP 1153
Query: 386 EAQRETVFVCASCNQTLS 403
V VC C L+
Sbjct: 1154 ------VRVCNICFDVLT 1165
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 38.1 bits (87), Expect = 0.014
Identities = 36/154 (23%), Positives = 53/154 (34%), Gaps = 14/154 (9%)
Query: 255 DGLMDSTPALT---PTEDLTPGSVEEAEEAEPDEEFKDAIEE---DDEGAPCPAEDELAL 308
+G DS + T P P V + + A+ E DDEG A
Sbjct: 210 EGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEA 269
Query: 309 QDNGFLSKNEVLRSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSF 366
N + + + + + R Y P + +C C FS+ + C CG F
Sbjct: 270 VQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGF 329
Query: 367 CSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQ 400
C C + S G P V VC +CN+
Sbjct: 330 CDECSHDRRAVPSRGWDHP------VRVCFNCNK 357
Score = 35.8 bits (81), Expect = 0.071
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 321 RSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKS 378
++ S LT+++ Y P + +C C+ +F + C CG FC C S P
Sbjct: 165 KAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVP 224
Query: 379 SMG-ATAPEAQRETVFVCASC 398
G AP V VC +C
Sbjct: 225 ERGWGPAP------VRVCDNC 239
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 38.1 bits (87), Expect = 0.014
Identities = 36/154 (23%), Positives = 53/154 (34%), Gaps = 14/154 (9%)
Query: 255 DGLMDSTPALT---PTEDLTPGSVEEAEEAEPDEEFKDAIEE---DDEGAPCPAEDELAL 308
+G DS + T P P V + + A+ E DDEG A
Sbjct: 625 EGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEA 684
Query: 309 QDNGFLSKNEVLRSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSF 366
N + + + + + R Y P + +C C FS+ + C CG F
Sbjct: 685 VQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGF 744
Query: 367 CSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQ 400
C C + S G P V VC +CN+
Sbjct: 745 CDECSHDRRAVPSRGWDHP------VRVCFNCNK 772
Score = 35.8 bits (81), Expect = 0.071
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 321 RSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKS 378
++ S LT+++ Y P + +C C+ +F + C CG FC C S P
Sbjct: 580 KAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVP 639
Query: 379 SMG-ATAPEAQRETVFVCASC 398
G AP V VC +C
Sbjct: 640 ERGWGPAP------VRVCDNC 654
>gi|217035164 coiled-coil domain containing 27 [Homo sapiens]
Length = 656
Score = 36.6 bits (83), Expect = 0.042
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Query: 207 LLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEEHAFESPPPPDVGG---KDGL------ 257
L +++L LG + + S + LQ ++E A E PD+GG +GL
Sbjct: 290 LSDASLKLGRLSLLKAFSRHEEELQHWWQMQEESAAPERGKEPDLGGGEEDEGLEGEPDG 349
Query: 258 MDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGAPCPAEDEL 306
++ T A + GSV E E +E +EE + +ED E P E+E+
Sbjct: 350 VEDTGAWGGVSQM--GSVHE-EGSEEEEEEEGDRDEDSEERELPEEEEI 395
>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.042
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 342 NCTGCSATF-SVLKKRRSCSNCGNSFCSRCCSFKVPKS 378
+C C TF S+ K+R C CG C +C FK S
Sbjct: 537 SCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENS 574
>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.042
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 342 NCTGCSATF-SVLKKRRSCSNCGNSFCSRCCSFKVPKS 378
+C C TF S+ K+R C CG C +C FK S
Sbjct: 537 SCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENS 574
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 36.2 bits (82), Expect = 0.054
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 343 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPE-AQRETVFVCASCNQT 401
C C F V+ ++ C CG FC +C SS +T P+ + V VC C +
Sbjct: 166 CHRCRVQFGVMTRKHHCRACGQIFCGKC-------SSKYSTIPKFGIEKEVRVCEPCYEQ 218
Query: 402 LSK 404
L++
Sbjct: 219 LNR 221
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,679,324
Number of Sequences: 37866
Number of extensions: 901552
Number of successful extensions: 6284
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 5912
Number of HSP's gapped (non-prelim): 369
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.