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Search of human proteins with 50557646
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50557646 zinc finger, FYVE domain containing 27 isoform a
[Homo sapiens]
(416 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Ho... 845 0.0
gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Ho... 830 0.0
gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Ho... 810 0.0
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 62 1e-09
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 54 3e-07
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 54 3e-07
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 52 8e-07
gi|217272865 myotubularin related protein 4 [Homo sapiens] 52 1e-06
gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens] 50 3e-06
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 49 6e-06
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 49 1e-05
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 48 2e-05
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 48 2e-05
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 47 3e-05
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 47 3e-05
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 47 3e-05
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 45 2e-04
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 45 2e-04
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 45 2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 45 2e-04
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 45 2e-04
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 45 2e-04
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 41 0.002
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 40 0.003
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 37 0.033
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 37 0.033
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 37 0.043
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 37 0.043
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 36 0.056
gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens] 35 0.096
>gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Homo
sapiens]
Length = 416
Score = 845 bits (2182), Expect = 0.0
Identities = 416/416 (100%), Positives = 416/416 (100%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETH 300
HAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETH
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETH 300
Query: 301 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 360
LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA
Sbjct: 301 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 360
Query: 361 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 416
TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 361 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 416
>gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Homo
sapiens]
Length = 411
Score = 830 bits (2145), Expect = 0.0
Identities = 411/416 (98%), Positives = 411/416 (98%), Gaps = 5/416 (1%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETH 300
HAFESPPPPDVGGKDGLMDSTPALTPTE DLTPGSVEEAEEAEPDEEFKDAIEETH
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTE-----DLTPGSVEEAEEAEPDEEFKDAIEETH 295
Query: 301 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 360
LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA
Sbjct: 296 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 355
Query: 361 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 416
TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 356 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 411
>gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Homo
sapiens]
Length = 404
Score = 810 bits (2093), Expect = 0.0
Identities = 404/416 (97%), Positives = 404/416 (97%), Gaps = 12/416 (2%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETH 300
HAFESPPPPDVGGKDGLMDSTPALTPTE DLTPGSVEEAEEAEPDEEFKDAIE
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTE-----DLTPGSVEEAEEAEPDEEFKDAIE--- 292
Query: 301 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 360
EDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA
Sbjct: 293 ----EDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 348
Query: 361 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 416
TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 349 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 404
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 61.6 bits (148), Expect = 1e-09
Identities = 63/252 (25%), Positives = 95/252 (37%), Gaps = 55/252 (21%)
Query: 206 TLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEEHAFESPPP-------PDVGG----- 253
T L STL L ++E + L P+ E A E PP P G
Sbjct: 902 TSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCANG 961
Query: 254 -----KDGL------MDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETHLV 302
KD L M + A + +L + L S + + PD+ + +++ +
Sbjct: 962 EAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMS 1021
Query: 303 VLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNN------FGN-- 354
V D + L ++G + E L+ +V L RL +Y T++ FG+
Sbjct: 1022 VYTDT------IQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEV 1075
Query: 355 ------------CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRE 402
C C + F + ++ C NCGN FCS CC+ KVP S P
Sbjct: 1076 MTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSR--- 1132
Query: 403 TVFVCASCNQTL 414
VC SC +L
Sbjct: 1133 ---VCKSCYSSL 1141
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 53.9 bits (128), Expect = 3e-07
Identities = 63/261 (24%), Positives = 95/261 (36%), Gaps = 64/261 (24%)
Query: 206 TLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEEHAFESPPP-------PDVGG----- 253
T L STL L ++E + L P+ E A E PP P G
Sbjct: 902 TSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCANG 961
Query: 254 -----KDGL------MDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETHLV 302
KD L M + A + +L + L S + + PD+ + +++ +
Sbjct: 962 EAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMS 1021
Query: 303 VLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNN------FGN-- 354
V D + L ++G + E L+ +V L RL +Y T++ FG+
Sbjct: 1022 VYTDT------IQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEV 1075
Query: 355 ------------CTGCSATFSVLKKRRSCS---------NCGNSFCSRCCSFKVPKSSMG 393
C C + F + ++ C NCGN FCS CC+ KVP S
Sbjct: 1076 MTRWLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQ 1135
Query: 394 ATAPEAQRETVFVCASCNQTL 414
P VC SC +L
Sbjct: 1136 LFEPSR------VCKSCYSSL 1150
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 53.5 bits (127), Expect = 3e-07
Identities = 48/186 (25%), Positives = 70/186 (37%), Gaps = 23/186 (12%)
Query: 242 AFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPD-EEFKDAIEETH 300
A SP P D D T T + + G +E E + +E K +E +
Sbjct: 1003 ATSSPDQPSRSHLDD--DGMSVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQY 1060
Query: 301 LVVLED------DEGAPCPAEDELALQDNGFLSK------NEVLRSKVSRLTERLRKRYP 348
L DE P D + D LS+ +E +V + + + P
Sbjct: 1061 LTSSLHFNGDFGDEVTSIP--DSESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLP 1118
Query: 349 TNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCA 408
+ +C C + F + ++ C NCGN FCS CC+ KVP S P VC
Sbjct: 1119 DHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSR------VCK 1172
Query: 409 SCNQTL 414
SC +L
Sbjct: 1173 SCYSSL 1178
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 52.4 bits (124), Expect = 8e-07
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 6/63 (9%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P G CT C A F+V++++ C +CG FCSRC S P G P V VC
Sbjct: 816 PDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKP------VRVC 869
Query: 408 ASC 410
C
Sbjct: 870 THC 872
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 51.6 bits (122), Expect = 1e-06
Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 17/129 (13%)
Query: 283 AEEAEPDEEFKDAIEETHLVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTER 342
A AEP +++D L++ +G+ ED + LS E V +
Sbjct: 1057 APPAEPPMDYED-----DFTCLKESDGSD--TEDFGSDHSEDCLS--EASWEPVDKKETE 1107
Query: 343 LRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQ-R 401
+ + P + +C C F + K+R C NCGN FC+ CC K+P P+ Q
Sbjct: 1108 VTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLP-------IPDQQLY 1160
Query: 402 ETVFVCASC 410
+ V VC SC
Sbjct: 1161 DPVLVCNSC 1169
>gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens]
Length = 471
Score = 50.4 bits (119), Expect = 3e-06
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 355 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 414
C GC+ F++ KK C NCG +FCS C SF A P VC C++ L
Sbjct: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSF-------SAAVPRTGNTQQKVCKQCHEVL 132
Query: 415 SK 416
++
Sbjct: 133 TR 134
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 49.3 bits (116), Expect = 6e-06
Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 6/63 (9%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P C C A F L ++ C CG FC RCCS KVP M P Q C
Sbjct: 43 PDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQ------C 96
Query: 408 ASC 410
A C
Sbjct: 97 AEC 99
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 48.5 bits (114), Expect = 1e-05
Identities = 19/48 (39%), Positives = 26/48 (54%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGAT 395
P + C CS F+ ++R C CG FCSRCC+ ++P MG T
Sbjct: 157 PDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYT 204
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 354 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 413
+C+GCS FS+ ++R C NCG FC +C F+ + ++P V VC +C
Sbjct: 214 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSP------VRVCQNCYYN 267
Query: 414 L 414
L
Sbjct: 268 L 268
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 354 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 413
+C+GCS FS+ ++R C NCG FC +C F+ + ++P V VC +C
Sbjct: 3459 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSP------VRVCQNCYYN 3512
Query: 414 L 414
L
Sbjct: 3513 L 3513
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 408 ASCNQTL 414
C+ L
Sbjct: 751 VICHSVL 757
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 408 ASCNQTL 414
C+ L
Sbjct: 751 VICHSVL 757
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 408 ASCNQTL 414
C+ L
Sbjct: 751 VICHSVL 757
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 11/103 (10%)
Query: 315 EDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFGNCTGCSATFSVLKKRRSC 371
E E ALQ+ G LS++++ + + + L+ + +C C FS+ +++ C
Sbjct: 497 EQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHC 556
Query: 372 SNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 414
NCG+ FC+ C S ++ A + + V VC SC+ L
Sbjct: 557 RNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTLL 591
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 11/103 (10%)
Query: 315 EDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFGNCTGCSATFSVLKKRRSC 371
E E ALQ+ G LS++++ + + + L+ + +C C FS+ +++ C
Sbjct: 497 EQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHC 556
Query: 372 SNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 414
NCG+ FC+ C S ++ A + + V VC SC+ L
Sbjct: 557 RNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTLL 591
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 11/103 (10%)
Query: 315 EDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFGNCTGCSATFSVLKKRRSC 371
E E ALQ+ G LS++++ + + + L+ + +C C FS+ +++ C
Sbjct: 605 EQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHC 664
Query: 372 SNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 414
NCG+ FC+ C S ++ A + + V VC SC+ L
Sbjct: 665 RNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTLL 699
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 8/67 (11%)
Query: 344 RKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRET 403
RK N NC C FSV +R C CGN FC+ C S+ A P + ++
Sbjct: 1347 RKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAEC-------SAKNALTP-SSKKP 1398
Query: 404 VFVCASC 410
V VC +C
Sbjct: 1399 VRVCDAC 1405
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P + NC C F+ K+R C CG FC CC+ K + A VC
Sbjct: 746 PDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEAR--------VC 797
Query: 408 ASCNQTLSK 416
C +T+SK
Sbjct: 798 VVCYETISK 806
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P + NC C F+ K+R C CG FC CC+ K + A VC
Sbjct: 746 PDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEAR--------VC 797
Query: 408 ASCNQTLSK 416
C +T+SK
Sbjct: 798 VVCYETISK 806
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 8/61 (13%)
Query: 354 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 413
+C C FS+ K++ C NCG FC+ C ++P S +P+ R VC SC+
Sbjct: 580 HCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPS----SPKPVR----VCDSCHAL 631
Query: 414 L 414
L
Sbjct: 632 L 632
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 338 RLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAP 397
RL + L K P + C C+A F V ++ C +CG C +C + ++P P
Sbjct: 1094 RLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKP 1153
Query: 398 EAQRETVFVCASCNQTLS 415
V VC C L+
Sbjct: 1154 ------VRVCNICFDVLT 1165
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 37.0 bits (84), Expect = 0.033
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 6/65 (9%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P + +C C FS+ + C CG FC C + S G P V VC
Sbjct: 299 PDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHP------VRVC 352
Query: 408 ASCNQ 412
+CN+
Sbjct: 353 FNCNK 357
Score = 35.8 bits (81), Expect = 0.074
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 333 RSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKS 390
++ S LT+++ Y P + +C C+ +F + C CG FC C S P
Sbjct: 165 KAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVP 224
Query: 391 SMG-ATAPEAQRETVFVCASC 410
G AP V VC +C
Sbjct: 225 ERGWGPAP------VRVCDNC 239
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 37.0 bits (84), Expect = 0.033
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 6/65 (9%)
Query: 348 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 407
P + +C C FS+ + C CG FC C + S G P V VC
Sbjct: 714 PDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHP------VRVC 767
Query: 408 ASCNQ 412
+CN+
Sbjct: 768 FNCNK 772
Score = 35.8 bits (81), Expect = 0.074
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 333 RSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKS 390
++ S LT+++ Y P + +C C+ +F + C CG FC C S P
Sbjct: 580 KAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVP 639
Query: 391 SMG-ATAPEAQRETVFVCASC 410
G AP V VC +C
Sbjct: 640 ERGWGPAP------VRVCDNC 654
>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.043
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 354 NCTGCSATF-SVLKKRRSCSNCGNSFCSRCCSFKVPKS 390
+C C TF S+ K+R C CG C +C FK S
Sbjct: 537 SCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENS 574
>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.043
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 354 NCTGCSATF-SVLKKRRSCSNCGNSFCSRCCSFKVPKS 390
+C C TF S+ K+R C CG C +C FK S
Sbjct: 537 SCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENS 574
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 36.2 bits (82), Expect = 0.056
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 355 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPE-AQRETVFVCASCNQT 413
C C F V+ ++ C CG FC +C SS +T P+ + V VC C +
Sbjct: 166 CHRCRVQFGVMTRKHHCRACGQIFCGKC-------SSKYSTIPKFGIEKEVRVCEPCYEQ 218
Query: 414 LSK 416
L++
Sbjct: 219 LNR 221
>gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens]
Length = 497
Score = 35.4 bits (80), Expect = 0.096
Identities = 58/257 (22%), Positives = 106/257 (41%), Gaps = 34/257 (13%)
Query: 52 EPLKDAGDGVRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAW--YSVGALMISVPALLGYL 109
EP+ G LL W+ PL SLL + N+LF L W Y + ++MI ++ +
Sbjct: 74 EPVLWLGCRADELLSWKRPLRSLLGFVAANLLFWFLALTPWRVYHLISVMILGRVIMQII 133
Query: 110 QEVCRARLPDSELMR---RKYHSVRQEDLQRGRLSR--PEAVAEVKSFLIQLEAFLSR-- 162
+++ +R ++L R + + + +R RLS E+ FL ++ F +
Sbjct: 134 KDMVLSRTRGAQLWRSLSESWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSP 193
Query: 163 -----LCCTCEAAYRVLHWENPVVSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNV 217
L C+ + +L G+ + V + YLL LC L L +G
Sbjct: 194 GKFCLLVCSVCTFFTIL------------GSYIPGVILSYLLLLCAFLCPLFKCNDIGQK 241
Query: 218 EFFRVVS---EYRASLQQRMNPKQEEHAFESPPPPDVGGKDGLMDSTPALTPTESL--SS 272
+ ++ S + + + +N K+ E S + KD AL P SL ++
Sbjct: 242 IYSKIKSVLLKLDFGIGEYINQKKRE---RSEADKEKSHKDDSELDFSALCPKISLTVAA 298
Query: 273 QDLTPGSVEEAEEAEPD 289
++L+ + +E + D
Sbjct: 299 KELSVSDTDVSEVSWTD 315
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,937,850
Number of Sequences: 37866
Number of extensions: 889809
Number of successful extensions: 5065
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 4917
Number of HSP's gapped (non-prelim): 192
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.