Guide to the Human Genome
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Search of human proteins with 48928027

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48928027 trefoil factor 3 precursor [Homo sapiens]
         (130 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48928027 trefoil factor 3 precursor [Homo sapiens]                 276   4e-75
gi|4507451 trefoil factor 1 precursor [Homo sapiens]                   72   2e-13
gi|4885629 trefoil factor 2 precursor [Homo sapiens]                   62   1e-10
gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]       39   9e-04
gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]       39   9e-04
gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]       39   9e-04
gi|10863987 zona pellucida glycoprotein 4 preproprotein [Homo sa...    32   0.14 
gi|221316699 maltase-glucoamylase [Homo sapiens]                       30   0.54 
gi|4505881 plasminogen [Homo sapiens]                                  30   0.54 
gi|189491675 hypothetical protein LOC84908 [Homo sapiens]              29   0.92 
gi|66348148 zona pellucida glycoprotein 1 [Homo sapiens]               29   0.92 
gi|11141861 claudin 9 [Homo sapiens]                                   28   1.6  
gi|24431958 solute carrier family 16, member 7 [Homo sapiens]          28   2.1  
gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [H...    28   2.7  
gi|153946395 tenascin C precursor [Homo sapiens]                       27   4.6  
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]                27   6.0  
gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo ...    27   6.0  
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]         27   6.0  
gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]           26   7.8  
gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]           26   7.8  
gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo ...    26   7.8  
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso...    26   7.8  

>gi|48928027 trefoil factor 3 precursor [Homo sapiens]
          Length = 130

 Score =  276 bits (705), Expect = 4e-75
 Identities = 130/130 (100%), Positives = 130/130 (100%)

Query: 1   MQERTGAATARRESLPQANNPEQLCKQRCINEASWTMKRVLSCVPEPTVVMAARALCMLG 60
           MQERTGAATARRESLPQANNPEQLCKQRCINEASWTMKRVLSCVPEPTVVMAARALCMLG
Sbjct: 1   MQERTGAATARRESLPQANNPEQLCKQRCINEASWTMKRVLSCVPEPTVVMAARALCMLG 60

Query: 61  LVLALLSSSSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCF 120
           LVLALLSSSSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCF
Sbjct: 61  LVLALLSSSSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCF 120

Query: 121 KPLQEAECTF 130
           KPLQEAECTF
Sbjct: 121 KPLQEAECTF 130


>gi|4507451 trefoil factor 1 precursor [Homo sapiens]
          Length = 84

 Score = 71.6 bits (174), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 45/85 (52%), Gaps = 9/85 (10%)

Query: 51  MAARALCMLGLVLALLSSSSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFD 110
           M  + +C L LV  L   + AE         C V  ++R +CG+P VTP +C N+GCCFD
Sbjct: 4   MENKVICALVLVSMLALGTLAEA----QTETCTVAPRERQNCGFPGVTPSQCANKGCCFD 59

Query: 111 SRIPGVPWCFKP-----LQEAECTF 130
             + GVPWCF P       E EC F
Sbjct: 60  DTVRGVPWCFYPNTIDVPPEEECEF 84


>gi|4885629 trefoil factor 2 precursor [Homo sapiens]
          Length = 129

 Score = 62.0 bits (149), Expect = 1e-10
 Identities = 29/68 (42%), Positives = 43/68 (63%), Gaps = 4/68 (5%)

Query: 61  LVLALLSSSSAEEYVGLSANQCA-VPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWC 119
           LVL L + + +E+    S  QC+ +   +R +CG+P +T  +C + GCCFDS + GVPWC
Sbjct: 13  LVLGLCALAGSEKP---SPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWC 69

Query: 120 FKPLQEAE 127
           F PL + E
Sbjct: 70  FHPLPKQE 77



 Score = 61.6 bits (148), Expect = 2e-10
 Identities = 23/52 (44%), Positives = 34/52 (65%)

Query: 79  ANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAECTF 130
           ++QC +   DR +CGYP ++P+EC +R CCF + I  VPWCF P    +C +
Sbjct: 78  SDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWCFFPKSVEDCHY 129


>gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score = 39.3 bits (90), Expect = 9e-04
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 8/50 (16%)

Query: 81  QCAVPAKDRVDCGYPH-VTPKECNNRGCCF-------DSRIPGVPWCFKP 122
           QC VP   R DC     +T ++C  RGCC+            G PWCF P
Sbjct: 81  QCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130


>gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score = 39.3 bits (90), Expect = 9e-04
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 8/50 (16%)

Query: 81  QCAVPAKDRVDCGYPH-VTPKECNNRGCCF-------DSRIPGVPWCFKP 122
           QC VP   R DC     +T ++C  RGCC+            G PWCF P
Sbjct: 81  QCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130


>gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score = 39.3 bits (90), Expect = 9e-04
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 8/50 (16%)

Query: 81  QCAVPAKDRVDCGYPH-VTPKECNNRGCCF-------DSRIPGVPWCFKP 122
           QC VP   R DC     +T ++C  RGCC+            G PWCF P
Sbjct: 81  QCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130


>gi|10863987 zona pellucida glycoprotein 4 preproprotein [Homo
           sapiens]
          Length = 540

 Score = 32.0 bits (71), Expect = 0.14
 Identities = 10/29 (34%), Positives = 18/29 (62%)

Query: 83  AVPAKDRVDCGYPHVTPKECNNRGCCFDS 111
           ++PA+DR+ C    ++  +C   GCC+ S
Sbjct: 145 SIPARDRLPCAPSPISRGDCEGLGCCYSS 173


>gi|221316699 maltase-glucoamylase [Homo sapiens]
          Length = 1857

 Score = 30.0 bits (66), Expect = 0.54
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 4/47 (8%)

Query: 77  LSANQCAVPAKDRVDCGYPHVTPKE--CNNRGCCFDSR-IPGVPWCF 120
           +SA    V   +R++C  P   P +  C+ RGCC++ +    VPWC+
Sbjct: 86  VSAECPVVNELERINC-IPDQPPTKATCDQRGCCWNPQGAVSVPWCY 131


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score = 30.0 bits (66), Expect = 0.54
 Identities = 15/30 (50%), Positives = 17/30 (56%), Gaps = 6/30 (20%)

Query: 81  QCAVPAKDRVDCGYPHVTPKECNNR---GC 107
           QCA P+    DCG P V PK+C  R   GC
Sbjct: 559 QCAAPS---FDCGKPQVEPKKCPGRVVGGC 585


>gi|189491675 hypothetical protein LOC84908 [Homo sapiens]
          Length = 138

 Score = 29.3 bits (64), Expect = 0.92
 Identities = 28/120 (23%), Positives = 49/120 (40%), Gaps = 14/120 (11%)

Query: 12  RESLPQANNPEQLCKQRCINEASWTMKRVLSCVPEPTVVMA-ARALCMLGLVLALLSSSS 70
           RE++ +       C   C  ++  +MK+V  C+    V +A A+AL    L         
Sbjct: 22  RENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVPLAQAQALVTSEL-------EK 74

Query: 71  AEEYVGLSANQCAVPAKDRVDCGYPHVTPKE----CNNRGCCFDSRIPGVPWCFKPLQEA 126
            ++ +      C   AKD +D G   +  K+    C  +  C D  +  +P   K ++EA
Sbjct: 75  FQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTK--CVDDHMHLIPTMTKKMKEA 132


>gi|66348148 zona pellucida glycoprotein 1 [Homo sapiens]
          Length = 638

 Score = 29.3 bits (64), Expect = 0.92
 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 3/41 (7%)

Query: 73  EYVG--LSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDS 111
           +Y+G  LS  QC V A   + C     + + C   GCC+D+
Sbjct: 225 DYIGTHLSQEQCQV-ASGHLPCIVRRTSKEACQQAGCCYDN 264


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score = 28.5 bits (62), Expect = 1.6
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 5/42 (11%)

Query: 47  PTVVMAARALCMLGLVLALLSSSSAEEYVGLSANQCAVPAKD 88
           P  + AARALC++ L+LALL        V ++  QC    +D
Sbjct: 74  PQDLQAARALCVIALLLALLGL-----LVAITGAQCTTCVED 110


>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
          Length = 478

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 14/27 (51%), Positives = 18/27 (66%)

Query: 49  VVMAARALCMLGLVLALLSSSSAEEYV 75
           VV+A   LC LG+VLA  SSS  + Y+
Sbjct: 88  VVIAGGLLCCLGMVLASFSSSVVQLYL 114


>gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [Homo
           sapiens]
          Length = 819

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 15/37 (40%), Positives = 16/37 (43%), Gaps = 4/37 (10%)

Query: 72  EEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCC 108
           E Y   S     V A +  DCG    TPKEC    CC
Sbjct: 410 EAYSAPSCGNKLVDAGEECDCG----TPKECELDPCC 442


>gi|153946395 tenascin C precursor [Homo sapiens]
          Length = 2201

 Score = 26.9 bits (58), Expect = 4.6
 Identities = 11/23 (47%), Positives = 13/23 (56%), Gaps = 1/23 (4%)

Query: 90  VDCGYPHVTPKECNNRGCCFDSR 112
           +DCG  H  P +CNN G C   R
Sbjct: 587 LDCGQ-HSCPSDCNNLGQCVSGR 608


>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
          Length = 2040

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 11/23 (47%), Positives = 13/23 (56%), Gaps = 2/23 (8%)

Query: 82   CAVP--AKDRVDCGYPHVTPKEC 102
            C +P  A    DCG P V PK+C
Sbjct: 1794 CDIPLCASSSFDCGKPQVEPKKC 1816


>gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo
           sapiens]
          Length = 299

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 11/23 (47%), Positives = 13/23 (56%), Gaps = 2/23 (8%)

Query: 82  CAVP--AKDRVDCGYPHVTPKEC 102
           C +P  A    DCG P V PK+C
Sbjct: 32  CDIPLCASSSFDCGKPQVEPKKC 54


>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
          Length = 1918

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 7/60 (11%)

Query: 69   SSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAEC 128
            S A ++  +    C++P + R+ CG  HV  + C+     +DS       C KP Q+  C
Sbjct: 1275 SKASDFQKVPEGGCSLPCEFRLGCG--HVCTRACHP----YDSSHKEFQ-CMKPCQKVIC 1327


>gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 55  ALCMLGLVLALLSSSSAEEYVGLSANQCAV---PAKDRVDCGYPHV 97
           A C+L   +ALLS++   E  G +A +C +    A +R+    PHV
Sbjct: 174 ATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAERLLGPPPHV 219


>gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 55  ALCMLGLVLALLSSSSAEEYVGLSANQCAV---PAKDRVDCGYPHV 97
           A C+L   +ALLS++   E  G +A +C +    A +R+    PHV
Sbjct: 174 ATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAERLLGPPPHV 219


>gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo
           sapiens]
          Length = 362

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 55  ALCMLGLVLALLSSSSAEEYVGLSANQCAV---PAKDRVDCGYPHV 97
           A C+L   +ALLS++   E  G +A +C +    A +R+    PHV
Sbjct: 174 ATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAERLLGPPPHV 219


>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
           [Homo sapiens]
          Length = 465

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 2/31 (6%)

Query: 80  NQCAVPAKDRVDCGYPHVTPKECNNRGCCFD 110
           N  +VP +D  D GY  +  K+C +  CCF+
Sbjct: 392 NNISVPQED--DYGYQCLEGKDCASFFCCFE 420


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.132    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,638,964
Number of Sequences: 37866
Number of extensions: 233064
Number of successful extensions: 516
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 501
Number of HSP's gapped (non-prelim): 27
length of query: 130
length of database: 18,247,518
effective HSP length: 90
effective length of query: 40
effective length of database: 14,839,578
effective search space: 593583120
effective search space used: 593583120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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