Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 48717285

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48717285 hypothetical protein LOC389763 [Homo sapiens]
         (1576 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48717285 hypothetical protein LOC389763 [Homo sapiens]            3199   0.0  
gi|223671858 hypothetical protein LOC389761 [Homo sapiens]           1690   0.0  
gi|223633944 hypothetical protein LOC389762 [Homo sapiens]           1688   0.0  
gi|165377334 hypothetical protein LOC727905 [Homo sapiens]            264   6e-70
gi|239743732 PREDICTED: family with sequence similarity 75, memb...   263   1e-69
gi|153791826 hypothetical protein LOC26165 [Homo sapiens]             261   4e-69
gi|91206406 hypothetical protein LOC642265 [Homo sapiens]             259   1e-68
gi|133892686 hypothetical protein LOC727830 [Homo sapiens]            259   1e-68
gi|169174618 PREDICTED: family with sequence similarity 75, memb...   259   1e-68
gi|146231958 hypothetical protein LOC647060 [Homo sapiens]            259   1e-68
gi|223633941 hypothetical protein LOC389730 [Homo sapiens]            259   2e-68
gi|155029550 chromosome 9 open reading frame 79 [Homo sapiens]        199   1e-50
gi|223468617 family with sequence similarity 75, member C1 [Homo...   154   6e-37
gi|213512168 hypothetical protein LOC259308 [Homo sapiens]             97   9e-20
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    62   3e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   6e-06
gi|149363676 hypothetical protein LOC404770 [Homo sapiens]             49   5e-05
gi|60460889 Myb protein P42POP [Homo sapiens]                          48   7e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    47   1e-04
gi|55741677 SET domain containing 1A [Homo sapiens]                    46   2e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                46   3e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                46   3e-04
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                46   3e-04
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             45   4e-04
gi|47132519 Ras association and pleckstrin homology domains 1 is...    45   7e-04
gi|148612879 polyhomeotic like 3 [Homo sapiens]                        44   0.001
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         44   0.001
gi|153792074 proline rich 12 [Homo sapiens]                            44   0.001
gi|56549694 enabled homolog isoform a [Homo sapiens]                   44   0.002
gi|39930375 enabled homolog isoform b [Homo sapiens]                   44   0.002

>gi|48717285 hypothetical protein LOC389763 [Homo sapiens]
          Length = 1576

 Score = 3199 bits (8293), Expect = 0.0
 Identities = 1576/1576 (100%), Positives = 1576/1576 (100%)

Query: 1    MENILCFLNSYTETGLSPDSHWLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNNDI 60
            MENILCFLNSYTETGLSPDSHWLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNNDI
Sbjct: 1    MENILCFLNSYTETGLSPDSHWLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNNDI 60

Query: 61   QKHQGRAKRRRKGGTFKGFPDWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHF 120
            QKHQGRAKRRRKGGTFKGFPDWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHF
Sbjct: 61   QKHQGRAKRRRKGGTFKGFPDWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHF 120

Query: 121  RRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATP 180
            RRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATP
Sbjct: 121  RRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATP 180

Query: 181  PEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP 240
            PEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP
Sbjct: 181  PEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP 240

Query: 241  QQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPI 300
            QQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPI
Sbjct: 241  QQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPI 300

Query: 301  PSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEFTWWQ 360
            PSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEFTWWQ
Sbjct: 301  PSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEFTWWQ 360

Query: 361  PHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLERQVK 420
            PHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLERQVK
Sbjct: 361  PHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLERQVK 420

Query: 421  KRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGKLEWQ 480
            KRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGKLEWQ
Sbjct: 421  KRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGKLEWQ 480

Query: 481  HIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHSSMFVFFNGITNTSI 540
            HIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHSSMFVFFNGITNTSI
Sbjct: 481  HIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHSSMFVFFNGITNTSI 540

Query: 541  SHESPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIR 600
            SHESPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIR
Sbjct: 541  SHESPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIR 600

Query: 601  ICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQEDFCPPAPNPELV 660
            ICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQEDFCPPAPNPELV
Sbjct: 601  ICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQEDFCPPAPNPELV 660

Query: 661  RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLRPQSKIS 720
            RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLRPQSKIS
Sbjct: 661  RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLRPQSKIS 720

Query: 721  ELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGYSQETV 780
            ELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGYSQETV
Sbjct: 721  ELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGYSQETV 780

Query: 781  PKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQKQLENALTVRLSKKFEE 840
            PKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQKQLENALTVRLSKKFEE
Sbjct: 781  PKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQKQLENALTVRLSKKFEE 840

Query: 841  INEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTSQEISFLSSNKQ 900
            INEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTSQEISFLSSNKQ
Sbjct: 841  INEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTSQEISFLSSNKQ 900

Query: 901  KMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLPSSATFISQGDSKDGV 960
            KMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLPSSATFISQGDSKDGV
Sbjct: 901  KMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLPSSATFISQGDSKDGV 960

Query: 961  SKSRSRSTFQGEKLGTTSSVPILDRPHPVSSPVVQEGQGTLRRQFSDTDHDLIETDSKDG 1020
            SKSRSRSTFQGEKLGTTSSVPILDRPHPVSSPVVQEGQGTLRRQFSDTDHDLIETDSKDG
Sbjct: 961  SKSRSRSTFQGEKLGTTSSVPILDRPHPVSSPVVQEGQGTLRRQFSDTDHDLIETDSKDG 1020

Query: 1021 ASTSLRRGTTDFQSEKLDSTSSFPILGHSYLVTSPVNQEKQGTLRREFSDTDNDLTESVR 1080
            ASTSLRRGTTDFQSEKLDSTSSFPILGHSYLVTSPVNQEKQGTLRREFSDTDNDLTESVR
Sbjct: 1021 ASTSLRRGTTDFQSEKLDSTSSFPILGHSYLVTSPVNQEKQGTLRREFSDTDNDLTESVR 1080

Query: 1081 TTEDGRQTFLPPPHSIVDEVSQKQTVLASRCSAELPIMQAGAGCESWDKRKSSFHNVDRL 1140
            TTEDGRQTFLPPPHSIVDEVSQKQTVLASRCSAELPIMQAGAGCESWDKRKSSFHNVDRL
Sbjct: 1081 TTEDGRQTFLPPPHSIVDEVSQKQTVLASRCSAELPIMQAGAGCESWDKRKSSFHNVDRL 1140

Query: 1141 QGSRKTFPVTNALQSQTRNNLTTSKSGSCSLTNVKASTSNETEIFPPRISVPQDPKSSYL 1200
            QGSRKTFPVTNALQSQTRNNLTTSKSGSCSLTNVKASTSNETEIFPPRISVPQDPKSSYL
Sbjct: 1141 QGSRKTFPVTNALQSQTRNNLTTSKSGSCSLTNVKASTSNETEIFPPRISVPQDPKSSYL 1200

Query: 1201 KNQMLSQLKLVQRKHSQPQSHFTDMSFALDNLSSKDLLTNSQGISSGDMGTSQVVHVHLE 1260
            KNQMLSQLKLVQRKHSQPQSHFTDMSFALDNLSSKDLLTNSQGISSGDMGTSQVVHVHLE
Sbjct: 1201 KNQMLSQLKLVQRKHSQPQSHFTDMSFALDNLSSKDLLTNSQGISSGDMGTSQVVHVHLE 1260

Query: 1261 DSGIRVAQKQEPRVPTCVLQKCQVTNFPPAVNRVSPVRPKGGELDGGDAGLGTSQRRRKS 1320
            DSGIRVAQKQEPRVPTCVLQKCQVTNFPPAVNRVSPVRPKGGELDGGDAGLGTSQRRRKS
Sbjct: 1261 DSGIRVAQKQEPRVPTCVLQKCQVTNFPPAVNRVSPVRPKGGELDGGDAGLGTSQRRRKS 1320

Query: 1321 LPVHNKTSGEVLGSKSSPTLKTQPPPENLFRKWMKTSLQWFNKPSISYEEQESSWEKGSS 1380
            LPVHNKTSGEVLGSKSSPTLKTQPPPENLFRKWMKTSLQWFNKPSISYEEQESSWEKGSS
Sbjct: 1321 LPVHNKTSGEVLGSKSSPTLKTQPPPENLFRKWMKTSLQWFNKPSISYEEQESSWEKGSS 1380

Query: 1381 LSSCVQNIGRVIRAAFTGTTEAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGK 1440
            LSSCVQNIGRVIRAAFTGTTEAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGK
Sbjct: 1381 LSSCVQNIGRVIRAAFTGTTEAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGK 1440

Query: 1441 AQHNPEVHVRAEPVQGCPCNYRAPSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQ 1500
            AQHNPEVHVRAEPVQGCPCNYRAPSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQ
Sbjct: 1441 AQHNPEVHVRAEPVQGCPCNYRAPSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQ 1500

Query: 1501 KVEAFKGKILCQSHPQSMPHRKPVPHPNPTCRRQVSLVCPAVPTSAKSPVFSDVPFLTGQ 1560
            KVEAFKGKILCQSHPQSMPHRKPVPHPNPTCRRQVSLVCPAVPTSAKSPVFSDVPFLTGQ
Sbjct: 1501 KVEAFKGKILCQSHPQSMPHRKPVPHPNPTCRRQVSLVCPAVPTSAKSPVFSDVPFLTGQ 1560

Query: 1561 KMLPKHLQGGKFPPTK 1576
            KMLPKHLQGGKFPPTK
Sbjct: 1561 KMLPKHLQGGKFPPTK 1576


>gi|223671858 hypothetical protein LOC389761 [Homo sapiens]
          Length = 917

 Score = 1690 bits (4376), Expect = 0.0
 Identities = 836/920 (90%), Positives = 864/920 (93%), Gaps = 3/920 (0%)

Query: 1   MENILCFLNSYTETGLSPDSHWLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNNDI 60
           MENILCFLNSYTETGLSPDSH LDID NFICLSGLGLFILYLFY+VLTLYSSPTEKNND 
Sbjct: 1   MENILCFLNSYTETGLSPDSHCLDIDLNFICLSGLGLFILYLFYMVLTLYSSPTEKNNDT 60

Query: 61  QKHQGRAKRRRKGGTFKGFPDWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHF 120
           QKHQGRA+R+RK  TFK   D KS Q+E EEERKL S LKSFGPPVSCSP GQHHDT  F
Sbjct: 61  QKHQGRARRKRKSVTFK---DRKSLQKEAEEERKLHSFLKSFGPPVSCSPLGQHHDTTLF 117

Query: 121 RRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATP 180
           RRLLCPDPVCRVC RATADIQ+LLSWESLKDAAPSVSPLASSAS  ESSFTLASTPSAT 
Sbjct: 118 RRLLCPDPVCRVCNRATADIQRLLSWESLKDAAPSVSPLASSASGAESSFTLASTPSATT 177

Query: 181 PEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP 240
           PEDLILS RPK SPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP
Sbjct: 178 PEDLILSSRPKPSPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP 237

Query: 241 QQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPI 300
           QQLPFPLLPPHHIERVE SLQPEASLSLNTIFSFGSTLCQDISQA+N  DSCARHHGPP 
Sbjct: 238 QQLPFPLLPPHHIERVEPSLQPEASLSLNTIFSFGSTLCQDISQAVNRTDSCARHHGPPT 297

Query: 301 PSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEFTWWQ 360
           PSALPPEDCTVTQSKS+LT+LKTFPEMLSLGGSGGSSTSAPT KGIDHS  ASSEF+WWQ
Sbjct: 298 PSALPPEDCTVTQSKSNLTVLKTFPEMLSLGGSGGSSTSAPTTKGIDHSCPASSEFSWWQ 357

Query: 361 PHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLERQVK 420
           PHAKDSFSSNFVPSDFMEELLTLHSSEA LGGHSVAN+I+PVNISFLSHDI ALLERQVK
Sbjct: 358 PHAKDSFSSNFVPSDFMEELLTLHSSEASLGGHSVANIIQPVNISFLSHDIPALLERQVK 417

Query: 421 KRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGKLEWQ 480
           +RGDFLMWKENGKKPGSFP QLRPNYQLNSSRNMLTS AVKHDLAESFPFWASKGKLEWQ
Sbjct: 418 RRGDFLMWKENGKKPGSFPTQLRPNYQLNSSRNMLTSTAVKHDLAESFPFWASKGKLEWQ 477

Query: 481 HIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHSSMFVFFNGITNTSI 540
           HIHQQPP+SKCFEDHLEQKYVQLFWGLPSLHSESLHPTV VQ G SSMFVFFNGITNTS+
Sbjct: 478 HIHQQPPYSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVFVQHGRSSMFVFFNGITNTSM 537

Query: 541 SHESPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIR 600
           SHESPVLPPPQPL LPSTQPLPLPQTLP+GQS HLTQVKSLAQPQSPF AL PSPLFLIR
Sbjct: 538 SHESPVLPPPQPLFLPSTQPLPLPQTLPRGQSLHLTQVKSLAQPQSPFPALPPSPLFLIR 597

Query: 601 ICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQEDFCPPAPNPELV 660
           +CGVCFHRPQNEARSL+PSEINHLEWNVLQKVQES+WGLPSVVQKSQEDFCPPAPNP LV
Sbjct: 598 VCGVCFHRPQNEARSLMPSEINHLEWNVLQKVQESVWGLPSVVQKSQEDFCPPAPNPVLV 657

Query: 661 RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLRPQSKIS 720
           RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIR+RLIQRRWGLPRRIHESLSLLRPQ+KIS
Sbjct: 658 RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRKRLIQRRWGLPRRIHESLSLLRPQNKIS 717

Query: 721 ELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGYSQETV 780
           ELSVSE IHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQG SQET 
Sbjct: 718 ELSVSESIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGCSQETA 777

Query: 781 PKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQKQLENALTVRLSKKFEE 840
           PK+HLLH PETSSD+DLRSNSERDL THMMHLSGNDSGVRLGQKQLENALTV LSKKFEE
Sbjct: 778 PKNHLLHDPETSSDEDLRSNSERDLGTHMMHLSGNDSGVRLGQKQLENALTVHLSKKFEE 837

Query: 841 INEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTSQEISFLSSNKQ 900
           INEGRMPGTVHSSWHSVKQT+ LPEKSHSQIKHRNL  LVSEDH VDTSQE+SFLSSNKQ
Sbjct: 838 INEGRMPGTVHSSWHSVKQTICLPEKSHSQIKHRNLAALVSEDHGVDTSQEMSFLSSNKQ 897

Query: 901 KMLEAHIKTFRMRMLWGLPL 920
           KMLEAHIK+F M+ +  L +
Sbjct: 898 KMLEAHIKSFHMKPILNLSI 917



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 15/42 (35%), Positives = 26/42 (61%)

Query: 895 LSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLS 936
           LSS  +K LE HI+   ++  WGLP ++ ES+ + + +  +S
Sbjct: 676 LSSEVRKKLEQHIRKRLIQRRWGLPRRIHESLSLLRPQNKIS 717


>gi|223633944 hypothetical protein LOC389762 [Homo sapiens]
          Length = 917

 Score = 1688 bits (4372), Expect = 0.0
 Identities = 835/920 (90%), Positives = 864/920 (93%), Gaps = 3/920 (0%)

Query: 1   MENILCFLNSYTETGLSPDSHWLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNNDI 60
           MENILCFLNSYTETGLSPDSH LDID NFICLSGLGLFILYLFY+VLTLYSSPTEKNND 
Sbjct: 1   MENILCFLNSYTETGLSPDSHCLDIDLNFICLSGLGLFILYLFYMVLTLYSSPTEKNNDT 60

Query: 61  QKHQGRAKRRRKGGTFKGFPDWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHF 120
           QKHQGRA+R+RK  TFK   D KS Q+E EEERKL S LKSFGPPVSCSP GQHHDT  F
Sbjct: 61  QKHQGRARRKRKSVTFK---DRKSLQKEAEEERKLHSFLKSFGPPVSCSPLGQHHDTTLF 117

Query: 121 RRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATP 180
           RRLLCPDPVCRVC RATADIQ+LLSWESLKDAAPSVSPLASSAS  ESSFTLASTPSAT 
Sbjct: 118 RRLLCPDPVCRVCNRATADIQRLLSWESLKDAAPSVSPLASSASGAESSFTLASTPSATT 177

Query: 181 PEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP 240
           PEDLILS RPK SPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP
Sbjct: 178 PEDLILSSRPKPSPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPP 237

Query: 241 QQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPI 300
           QQLPFPLLPPHHIERVE SLQPEASLSLNTIFSFGSTLCQDISQA+N  DSCARHHGPP 
Sbjct: 238 QQLPFPLLPPHHIERVEPSLQPEASLSLNTIFSFGSTLCQDISQAVNRTDSCARHHGPPT 297

Query: 301 PSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEFTWWQ 360
           PSALPPEDCTVTQSKS+LT+LKTFPEMLSLGGSGGSSTSAPT KGIDHS  ASSEF+WWQ
Sbjct: 298 PSALPPEDCTVTQSKSNLTVLKTFPEMLSLGGSGGSSTSAPTTKGIDHSCPASSEFSWWQ 357

Query: 361 PHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLERQVK 420
           PHAKDSFSSNFVPSDFMEELLTLHSSEA LGGHSVAN+I+PVNISFLSHDI ALLERQVK
Sbjct: 358 PHAKDSFSSNFVPSDFMEELLTLHSSEASLGGHSVANIIQPVNISFLSHDIPALLERQVK 417

Query: 421 KRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGKLEWQ 480
           +RGDFLMWKENGKKPGSFP QLRPNYQLNSSRNMLTS AVKHDLAESFPFWASKGKLEWQ
Sbjct: 418 RRGDFLMWKENGKKPGSFPTQLRPNYQLNSSRNMLTSTAVKHDLAESFPFWASKGKLEWQ 477

Query: 481 HIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHSSMFVFFNGITNTSI 540
           HIHQQPP+SKCFEDHLEQKYVQLFWGLPSLHSESLHPTV VQ G SSMFVFFNGITNTS+
Sbjct: 478 HIHQQPPYSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVFVQHGRSSMFVFFNGITNTSM 537

Query: 541 SHESPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIR 600
           SHESPVLPPPQPL LPSTQPLPLPQTLP+GQS HLTQVKSLAQPQSPF AL PSPLFLIR
Sbjct: 538 SHESPVLPPPQPLFLPSTQPLPLPQTLPRGQSLHLTQVKSLAQPQSPFPALPPSPLFLIR 597

Query: 601 ICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQEDFCPPAPNPELV 660
           +CGVCFHRPQNEARSL+PSEINHLEWNVLQKVQES+WGLPSVVQKSQEDFCPPAPNP LV
Sbjct: 598 VCGVCFHRPQNEARSLMPSEINHLEWNVLQKVQESVWGLPSVVQKSQEDFCPPAPNPVLV 657

Query: 661 RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLRPQSKIS 720
           RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIR+RLIQRRWGLPRRIHESLSLLRPQ+KIS
Sbjct: 658 RKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRKRLIQRRWGLPRRIHESLSLLRPQNKIS 717

Query: 721 ELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGYSQETV 780
           ELSVSE IHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQG SQET 
Sbjct: 718 ELSVSESIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGCSQETA 777

Query: 781 PKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQKQLENALTVRLSKKFEE 840
           PK+HLLH PETSS++DLRSNSERDL THMMHLSGNDSGVRLGQKQLENALTV LSKKFEE
Sbjct: 778 PKNHLLHDPETSSEEDLRSNSERDLGTHMMHLSGNDSGVRLGQKQLENALTVHLSKKFEE 837

Query: 841 INEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTSQEISFLSSNKQ 900
           INEGRMPGTVHSSWHSVKQT+ LPEKSHSQIKHRNL  LVSEDH VDTSQE+SFLSSNKQ
Sbjct: 838 INEGRMPGTVHSSWHSVKQTICLPEKSHSQIKHRNLAALVSEDHRVDTSQEMSFLSSNKQ 897

Query: 901 KMLEAHIKTFRMRMLWGLPL 920
           KMLEAHIK+F M+ +  L +
Sbjct: 898 KMLEAHIKSFHMKPILNLSI 917



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 15/42 (35%), Positives = 26/42 (61%)

Query: 895 LSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLS 936
           LSS  +K LE HI+   ++  WGLP ++ ES+ + + +  +S
Sbjct: 676 LSSEVRKKLEQHIRKRLIQRRWGLPRRIHESLSLLRPQNKIS 717


>gi|165377334 hypothetical protein LOC727905 [Homo sapiens]
          Length = 1347

 Score =  264 bits (674), Expect = 6e-70
 Identities = 285/972 (29%), Positives = 425/972 (43%), Gaps = 133/972 (13%)

Query: 1   MENILCFLNSYTETGLSPDSH--WLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNN 58
           MEN+   L   + + L+  S   W+ +D     +  LG F L L Y+       P   + 
Sbjct: 1   MENLPFPLKLLSASSLNAPSSTPWV-LDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSP 59

Query: 59  DIQKHQGRAKRRRKGGTFKGFP--DWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHD 116
             +K     +RRR  G  K       +  +R  EE   LLS L+S          G H D
Sbjct: 60  GKRKCPV-GRRRRPRGRMKNHSLRAGRECRRGLEETSDLLSQLQSL--------LGPHLD 110

Query: 117 TNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTP 176
              F +L  PDP   V +RA     Q  S E ++DAAP +SPLAS              P
Sbjct: 111 KGDFGQLSGPDPPGEVGERAPDGASQS-SHEPMEDAAPILSPLASP------------DP 157

Query: 177 SATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
            A  P+DL  +P            SP  +TT     S S L    PP+P  PL+   P  
Sbjct: 158 QAKHPQDLASTP------------SPGPMTT-----SVSSLSASQPPEPSLPLEHPSP-- 198

Query: 237 HSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHH 296
             PP   P P   PH  + +  SL P    +   +    STL        +  DS A   
Sbjct: 199 -EPPALFPHP---PHTPDPLACSLPPPKGFTAPPLRD--STLITP-----SHCDSVAFPL 247

Query: 297 GPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEF 356
           G    S  P ED           ++ + P +  LGGS              +SH+++S  
Sbjct: 248 GTVPQSLSPHED-----------LVASVPAISGLGGS--------------NSHVSAS-- 280

Query: 357 TWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLE 416
           + WQ  A+ S + N   S   ++ L+ H  E           +E  ++  LS D   ++ 
Sbjct: 281 SRWQETARTSCAFN---SSVQQDHLSRHPPETCQ--------MEAGSLFLLSSDGQNVVG 329

Query: 417 RQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGK 476
            QV +     +W+E  +  GSF  ++ P   LNS RN+  S+  + D     PFW     
Sbjct: 330 IQVTETAKVNIWEEK-ENVGSFTNRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGEN 388

Query: 477 LEWQHIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLV-QRGHS--SMFVFFN 533
            +     Q+    + +++   + Y QLFWGLPSLHSESL     V  R ++  S    FN
Sbjct: 389 SKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFN 448

Query: 534 GITNTS-ISHE---SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFR 589
            ++N   I  E   SP+L   QPLS    +  P   + PQ +   + Q ++ A  QS F 
Sbjct: 449 EMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFP 508

Query: 590 ALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQED 649
            L P+   LI+  GV     QN+ ++L   E  H EW +L++  E    LPS VQKSQ+ 
Sbjct: 509 VLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDV 568

Query: 650 FCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHES 709
           F    PN  L ++S       SI+P +FP+S E+R++LEQHI++ +IQ  WG   RI ES
Sbjct: 569 FSVSTPN--LPQESL-----TSILPENFPVSPELRRQLEQHIKKWIIQ-HWGNLGRIQES 620

Query: 710 LSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENV 769
           L L++ + +    S ++    P   S+  G+     +K      R             ++
Sbjct: 621 LDLMQLRDESPGTSQAKGKPSPWQSSMSTGEGSKEAQKVKFQLERD---------PCPHL 671

Query: 770 GNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRL----GQKQ 825
           G   G + + + +D        S  + +   +  +LE ++     +DSG  L     +  
Sbjct: 672 GQILGETPQNLSRD------MKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTH 725

Query: 826 LENALTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHC 885
           +EN L   + +   + NEG +P  V  SW +V Q + +   S++ +K  NL    S   C
Sbjct: 726 IENILKAHMGRNLGQTNEGLIPVCVRRSWLAVNQALPV---SNTHVKTSNLAAPKSGKAC 782

Query: 886 VDTSQEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLP 945
           V+T+Q +SFL    Q+ L AHI  F  +  WGLPL+VL+ I+ FK +   S S +    P
Sbjct: 783 VNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGP 842

Query: 946 SSATFISQGDSK 957
           SSAT  S   S+
Sbjct: 843 SSATCESGAGSE 854



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 106/437 (24%), Positives = 179/437 (40%), Gaps = 97/437 (22%)

Query: 1146 TFPVTNALQSQTRNNLTTSKSG--------------SCSLTNVKASTSNETEIFP----- 1186
            T+ +T ++Q        +SK+G              +C L N++A TS +   F      
Sbjct: 928  TYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQA-TSEDVHGFEAPGTS 986

Query: 1187 -----PRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTDMSFAL 1229
                 PR+SV QDP+   L  +++++ +  +  +  +QPQ             + +  A 
Sbjct: 987  KSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHAS 1046

Query: 1230 DNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQVTNFP 1288
            +NL S+    + Q + +G+M  SQ +H  +     ++   +EPR P C    K Q   FP
Sbjct: 1047 ENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVH-EEPRNPNCQGSCKSQRPMFP 1105

Query: 1289 PAVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLKTQPPP 1346
            P        +P   + +    GL T Q    RK+   H     ++L SK       QPP 
Sbjct: 1106 PIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK------QPPS 1159

Query: 1347 ENLFRKWMKTSLQWF-----NKPS-ISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTT 1400
             + F + +K   QW      +KP+ ++ E Q++           V+N  RV    ++ + 
Sbjct: 1160 VSPFGENIKQIFQWIFSKKKSKPAPVTAESQKT-----------VKNRSRV----YSSSA 1204

Query: 1401 EAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQG 1456
            EAQ +     + L+EK+   H                   A+H  +V+   +    PV G
Sbjct: 1205 EAQGLMTAVGQMLDEKMSLCH-------------------ARHASKVNQHKQKFQAPVCG 1245

Query: 1457 CPCNYR----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQ 1512
             PCN+R    +   ++    + SQQA    Q  P R RQI  +++QP K      +    
Sbjct: 1246 FPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGL 1303

Query: 1513 SHPQSMPHRKPVPHPNP 1529
             HPQ +  +K V   +P
Sbjct: 1304 RHPQILHPKKAVSPVSP 1320


>gi|239743732 PREDICTED: family with sequence similarity 75, member
           A4 isoform 1 [Homo sapiens]
          Length = 1361

 Score =  263 bits (672), Expect = 1e-69
 Identities = 284/972 (29%), Positives = 425/972 (43%), Gaps = 133/972 (13%)

Query: 1   MENILCFLNSYTETGLSPDSH--WLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNN 58
           MEN+   L   + + L+  S   W+ +D     +  LG F + L Y+       P   + 
Sbjct: 15  MENLPFPLKLLSASSLNAPSSTPWV-LDIFLTLVFALGFFFVLLPYLSYFRCDDPPSPSP 73

Query: 59  DIQKHQGRAKRRRKGGTFKGFP--DWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHD 116
             +K     +RRR  G  K       +  +R  EE   LLS L+S          G H D
Sbjct: 74  GKRKCPV-GRRRRPRGRMKNHSLRAGRECRRGLEETSDLLSQLQSL--------LGPHLD 124

Query: 117 TNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTP 176
              F +L  PDP   V +RA     Q  S E ++DAAP +SPLAS              P
Sbjct: 125 KGDFGQLSGPDPPGEVGERAPDGASQS-SHEPMEDAAPILSPLASP------------DP 171

Query: 177 SATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
            A  P+DL  +P            SP  +TT     S S L    PP+P  PL+   P  
Sbjct: 172 QAKHPQDLASTP------------SPGPMTT-----SVSSLSASQPPEPSLPLEHPSP-- 212

Query: 237 HSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHH 296
             PP   P P   PH  + +  SL P    +   +    STL        +  DS A   
Sbjct: 213 -EPPALFPHP---PHTPDPLACSLPPPKGFTAPPLRD--STLITP-----SHCDSVAFPL 261

Query: 297 GPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEF 356
           G    S  P ED           ++ + P +  LGGS              +SH+++S  
Sbjct: 262 GTVPQSLSPHED-----------LVASVPAISGLGGS--------------NSHVSAS-- 294

Query: 357 TWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLE 416
           + WQ  A+ S + N   S   ++ L+ H  E           +E  ++  LS D   ++ 
Sbjct: 295 SRWQETARTSCAFN---SSVQQDHLSRHPPETCQ--------MEAGSLFLLSSDGQNVVG 343

Query: 417 RQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGK 476
            QV +     +W+E  +  GSF  ++ P   LNS RN+  S+  + D     PFW     
Sbjct: 344 IQVTETAKVNIWEEK-ENVGSFTNRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGEN 402

Query: 477 LEWQHIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLV-QRGHS--SMFVFFN 533
            +     Q+    + +++   + Y QLFWGLPSLHSESL     V  R ++  S    FN
Sbjct: 403 SKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFN 462

Query: 534 GITNTS-ISHE---SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFR 589
            ++N   I  E   SP+L   QPLS    +  P   + PQ +   + Q ++ A  QS F 
Sbjct: 463 EMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFP 522

Query: 590 ALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQED 649
            L P+   LI+  GV     QN+ ++L   E  H EW +L++  E    LPS VQKSQ+ 
Sbjct: 523 VLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDV 582

Query: 650 FCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHES 709
           F    PN  L ++S       SI+P +FP+S E+R++LEQHI++ +IQ  WG   RI ES
Sbjct: 583 FSVSTPN--LPQESL-----TSILPENFPVSPELRRQLEQHIKKWIIQ-HWGNLGRIQES 634

Query: 710 LSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENV 769
           L L++ + +    S ++    P   S+  G+     +K      R             ++
Sbjct: 635 LDLMQLRDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERD---------PCPHL 685

Query: 770 GNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRL----GQKQ 825
           G   G + + + +D        S  + +   +  +LE ++     +DSG  L     +  
Sbjct: 686 GQILGETPQNLSRD------MKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTH 739

Query: 826 LENALTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHC 885
           +EN L   + +   + NEG +P  V  SW +V Q + +   S++ +K  NL    S   C
Sbjct: 740 IENILKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPV---SNTHVKTSNLAAPKSGKAC 796

Query: 886 VDTSQEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLP 945
           V+T+Q +SFL    Q+ L AHI  F  +  WGLPL+VL+ I+ FK +   S S +    P
Sbjct: 797 VNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGP 856

Query: 946 SSATFISQGDSK 957
           SSAT  S   S+
Sbjct: 857 SSATCESGAGSE 868



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 105/437 (24%), Positives = 179/437 (40%), Gaps = 97/437 (22%)

Query: 1146 TFPVTNALQSQTRNNLTTSKSG--------------SCSLTNVKASTSNETEIFP----- 1186
            T+ +T ++Q        +SK+G              +C L N++A TS +   F      
Sbjct: 942  TYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQA-TSEDVHGFEAPGTS 1000

Query: 1187 -----PRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTDMSFAL 1229
                 PR+SV QDP+   L  +++++ +  +  +  +QPQ             + +  A 
Sbjct: 1001 KSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHAS 1060

Query: 1230 DNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQVTNFP 1288
            +NL S+    + Q + +G+M  SQ +H  +     ++   +EPR P C    K Q   FP
Sbjct: 1061 ENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVH-EEPRNPNCQGSCKSQRPMFP 1119

Query: 1289 PAVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLKTQPPP 1346
            P        +P   + +    GL T Q    RK+   H     ++L SK       QPP 
Sbjct: 1120 PIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK------QPPS 1173

Query: 1347 ENLFRKWMKTSLQWF-----NKPS-ISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTT 1400
             + F + +K   QW      +KP+ ++ E Q++           V+N  RV    ++ + 
Sbjct: 1174 VSPFGENIKQIFQWIFSKKKSKPAPVTAESQKT-----------VKNRSRV----YSSSA 1218

Query: 1401 EAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQG 1456
            EAQ +     + L++K+   H                   A+H  +V+   +    PV G
Sbjct: 1219 EAQGLMTAVGQMLDKKMSLCH-------------------ARHASKVNQHKQKFQAPVCG 1259

Query: 1457 CPCNYR----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQ 1512
             PCN+R    +   ++    + SQQA    Q  P R RQI  +++QP K      +    
Sbjct: 1260 FPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGL 1317

Query: 1513 SHPQSMPHRKPVPHPNP 1529
             HPQ +  +K V   +P
Sbjct: 1318 RHPQILHPKKAVSPVSP 1334


>gi|153791826 hypothetical protein LOC26165 [Homo sapiens]
          Length = 1347

 Score =  261 bits (667), Expect = 4e-69
 Identities = 284/972 (29%), Positives = 423/972 (43%), Gaps = 133/972 (13%)

Query: 1   MENILCFLNSYTETGLSPDSH--WLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNN 58
           MEN+   L   + + L+  S   W+ +D     +  LG F L L Y+       P   + 
Sbjct: 1   MENLPFPLKLLSASSLNAPSSTPWV-LDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSP 59

Query: 59  DIQKHQGRAKRRRKGGTFKGFP--DWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHD 116
             +K     +RRR  G  K       +   R  EE   LLS L+S          G H D
Sbjct: 60  GKRKCPV-GRRRRPRGRMKNHSLRAGRECPRGLEETSDLLSQLQSL--------LGPHLD 110

Query: 117 TNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTP 176
              F +L  PDP   V +RA     Q  S E ++DAAP +SPLAS              P
Sbjct: 111 KGDFGQLSGPDPPGEVGERAPDGASQS-SHEPMEDAAPILSPLASP------------DP 157

Query: 177 SATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
            A  P+DL  +P            SP  +TT     S S L    PP+P  PL+   P  
Sbjct: 158 QAKHPQDLASTP------------SPGPMTT-----SVSSLSASQPPEPSLPLEHPSP-- 198

Query: 237 HSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHH 296
             PP   P P   PH  + +  SL P    +   +    STL        +  DS A   
Sbjct: 199 -EPPALFPHP---PHTPDPLACSLPPPKGFTAPPLRD--STLITP-----SHCDSVAFPL 247

Query: 297 GPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEF 356
           G    S  P ED           ++ + P +  LGGS              +SH+++S  
Sbjct: 248 GTVPQSLSPHED-----------LVASVPAISGLGGS--------------NSHVSAS-- 280

Query: 357 TWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLE 416
           + WQ  A+ S + N   S   ++ L+ H  E           +E  ++  LS D   ++ 
Sbjct: 281 SRWQETARTSCAFN---SSVQQDHLSRHPPETCQ--------MEAGSLFLLSSDGQNVVG 329

Query: 417 RQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGK 476
            QV +     +W+E  +  GSF  ++ P   LN  RN+  S+  + D     PFW     
Sbjct: 330 IQVTETAKVNIWEEK-ENVGSFTNRMTPEKHLNYLRNLAKSLDAEQDTTNPKPFWNMGEN 388

Query: 477 LEWQHIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLV-QRGHS--SMFVFFN 533
            +     Q+    + +++   + Y QLFWGLPSLHSESL     V  R ++  S    FN
Sbjct: 389 SKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFN 448

Query: 534 GITNTS-ISHE---SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFR 589
            ++N   I  E   SP+L   QPLS    +  P   + PQ +   + Q ++ A  QS F 
Sbjct: 449 EMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFP 508

Query: 590 ALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQED 649
            L P+   LI+  GV     QN+ ++L   E  H EW +L++  E    LPS VQKSQ+ 
Sbjct: 509 VLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDV 568

Query: 650 FCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHES 709
           F    PN  L ++S       SI+P +FP+S E+R++LEQHI++ +IQ  WG   RI ES
Sbjct: 569 FSVSTPN--LPQESL-----TSILPENFPVSPELRRQLEQHIKKWIIQ-HWGNLGRIQES 620

Query: 710 LSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENV 769
           L L++ + +    S ++    P   S+  G+     +K      R             ++
Sbjct: 621 LDLMQLRDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERD---------PCPHL 671

Query: 770 GNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRL----GQKQ 825
           G   G + + + +D        S  + +   +  +LE ++     +DSG  L     +  
Sbjct: 672 GQILGETPQNLSRD------MKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTH 725

Query: 826 LENALTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHC 885
           +EN L   + +   + NEG +P  V  SW +V Q + +   S++ +K  NL    S   C
Sbjct: 726 IENILKAHMGRNLGQTNEGLIPVCVRRSWLAVNQALPV---SNTHVKTSNLAAPKSGKAC 782

Query: 886 VDTSQEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLP 945
           V+T+Q +SFL    Q+ L AHI  F  +  WGLPL+VL+ I+ FK +   S S +    P
Sbjct: 783 VNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGP 842

Query: 946 SSATFISQGDSK 957
           SSAT  S   S+
Sbjct: 843 SSATCESGAGSE 854



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 106/437 (24%), Positives = 179/437 (40%), Gaps = 97/437 (22%)

Query: 1146 TFPVTNALQSQTRNNLTTSKSG--------------SCSLTNVKASTSNETEIFP----- 1186
            T+ +T ++Q        +SK+G              +C L N++A TS +   F      
Sbjct: 928  TYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQA-TSEDVHGFEAPGTS 986

Query: 1187 -----PRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTDMSFAL 1229
                 PR+SV QDP+   L  +++++ +  +  +  +QPQ             + +  A 
Sbjct: 987  KSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHAS 1046

Query: 1230 DNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQVTNFP 1288
            +NL S+    + Q + +G+M  SQ +H  +     ++   +EPR P C    K Q   FP
Sbjct: 1047 ENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVH-EEPRNPNCQGSCKSQRPMFP 1105

Query: 1289 PAVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLKTQPPP 1346
            P        +P   + +    GL T Q    RK+   H     ++L SK       QPP 
Sbjct: 1106 PIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK------QPPS 1159

Query: 1347 ENLFRKWMKTSLQWF-----NKPS-ISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTT 1400
             + F + +K   QW      +KP+ ++ E Q++           V+N  RV    ++ + 
Sbjct: 1160 VSPFGENIKQIFQWIFSKKKSKPAPVTAESQKT-----------VKNRSRV----YSSSA 1204

Query: 1401 EAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQG 1456
            EAQ +     + L+EK+   H                   A+H  +V+   +    PV G
Sbjct: 1205 EAQGLMTAVGQMLDEKMSLCH-------------------ARHASKVNQHKQKFQAPVCG 1245

Query: 1457 CPCNYR----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQ 1512
             PCN+R    +   ++    + SQQA    Q  P R RQI  +++QP K      +    
Sbjct: 1246 FPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGL 1303

Query: 1513 SHPQSMPHRKPVPHPNP 1529
             HPQ +  +K V   +P
Sbjct: 1304 RHPQILHPKKAVSPVSP 1320


>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
          Length = 1347

 Score =  259 bits (663), Expect = 1e-68
 Identities = 282/968 (29%), Positives = 420/968 (43%), Gaps = 125/968 (12%)

Query: 1   MENILCFLNSYTETGLSPDSH--WLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNN 58
           MEN+   L   + + L+  S   W+ +D     +  LG F L L Y+       P   + 
Sbjct: 1   MENLPFPLKLLSASSLNAPSSTPWV-LDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSP 59

Query: 59  DIQKHQGRAKRRRKGGTFKGFP--DWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHD 116
             +K     +RRR  G  K       +  +R  +E   LLS L+S          G H D
Sbjct: 60  GKRKCPV-GRRRRPRGRMKNHSLRAGRECRRGLQETSDLLSQLQSL--------LGPHLD 110

Query: 117 TNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTP 176
              F +L  PDP   V +RA     Q  S E ++DAAP +SPLAS              P
Sbjct: 111 KGDFGQLSGPDPPGEVGERAPDGASQS-SHEPMEDAAPILSPLASP------------DP 157

Query: 177 SATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
            A  P+DL  +P            SP  +TT     S S L    PP+P  PL+   P  
Sbjct: 158 QAKHPQDLASTP------------SPGPMTT-----SVSSLSASQPPEPSLPLEHPSP-- 198

Query: 237 HSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHH 296
             PP   P P   PH  + +  S  P    +   +    STL        +  DS A   
Sbjct: 199 -EPPALFPHP---PHTPDPLACSPPPPKGFTAPPLRD--STLITP-----SHCDSVALPL 247

Query: 297 GPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEF 356
           G    S  P ED           ++ + P +  LGGS              +SH+++S  
Sbjct: 248 GTVPQSLSPHED-----------LVASVPAISGLGGS--------------NSHVSAS-- 280

Query: 357 TWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLE 416
           + WQ  A+ S + N   S   ++ L+ H  E +         +E  ++  LS D    + 
Sbjct: 281 SRWQETARTSCAFN---SSVQQDHLSRHPPETYQ--------MEAGSLFLLSSDGQNAVG 329

Query: 417 RQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGK 476
            QV +     +W+E  +  GSF  ++ P   LNS RN+  S+  + D     PFW     
Sbjct: 330 IQVTETAKVNIWEEK-ENVGSFTDRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGEN 388

Query: 477 LEWQHIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLV-QRGHS--SMFVFFN 533
            +     Q+    + +++   + Y QLFWGLPSLHSESL     V  R ++  S    FN
Sbjct: 389 SKQLPGPQKFSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFN 448

Query: 534 GITNTS-ISHE---SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFR 589
            ++N   I  E   SP+L   QP S    +  P   + PQ +   + Q ++ A  QS F 
Sbjct: 449 EMSNVCPIQRETTMSPLLFQAQPPSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFP 508

Query: 590 ALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQED 649
            L P+   LI+  GV     QN+ ++L   E  H EW +L++  E    LPS VQKSQ+ 
Sbjct: 509 VLSPAFPSLIKNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDV 568

Query: 650 FCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHES 709
           F    PN  L ++S       SI+P +FP+S E+R++LEQHI++ +IQ  WG   RI ES
Sbjct: 569 FSVSTPN--LPQESLT-----SILPENFPVSPELRRQLEQHIKKWIIQH-WGNLGRIQES 620

Query: 710 LSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENV 769
           L L++ + +    S ++    P   S+  G+     +K      R             ++
Sbjct: 621 LDLMQLRDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERD---------PCPHL 671

Query: 770 GNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQKQLENA 829
           G   G + + + +D      +          SER+L   +   SG+D      +  +EN 
Sbjct: 672 GQILGETPQNLSRDMKSFPRKVLGVTS--EESERNLRKPLRSDSGSDLLRCTERTHIENI 729

Query: 830 LTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTS 889
           L   + +   + NEG +P  V  SW +V Q + +   S++ +K  NL    S   CV+T+
Sbjct: 730 LKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPV---SNTHVKTSNLAAPKSGKACVNTA 786

Query: 890 QEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLPSSAT 949
           Q +SFL    Q+ L AHI  F  +  WGLPL+VL+ I+ FK +   S S +    PSSAT
Sbjct: 787 QVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSAT 846

Query: 950 FISQGDSK 957
             S   S+
Sbjct: 847 CESGAGSE 854



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 101/431 (23%), Positives = 170/431 (39%), Gaps = 85/431 (19%)

Query: 1146 TFPVTNALQSQTRNNLTTSKSG--------------SCSLTNVKASTSN---------ET 1182
            T+ +T + Q        +SK+G              +C L N++A++ +           
Sbjct: 928  TYSLTGSTQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDMHGFEAPGTSK 987

Query: 1183 EIFPPRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTDMSFALD 1230
                PR+SV QDP+   L  +++++ +  +  +  +QPQ             + +  A +
Sbjct: 988  SSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASE 1047

Query: 1231 NLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQVTNFPP 1289
            NL S+    + Q + +G+M  SQ +H  +     ++   +EPR P C    K Q   FPP
Sbjct: 1048 NLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVH-EEPRNPNCQGSCKSQRPMFPP 1106

Query: 1290 AVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLKTQPPPE 1347
                    +P   + +    GL T Q    RK+   H     ++L SK       QPP  
Sbjct: 1107 IHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK------QPPSV 1160

Query: 1348 NLFRKWMKTSLQW-FNKPSISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTTEAQKIR 1406
            + F   +K   QW F+K         +  +K     SCV          ++ + EAQ + 
Sbjct: 1161 SHFGGNIKQFFQWIFSKKKSKPAPVTAESQKTVKNRSCV----------YSSSAEAQGLM 1210

Query: 1407 KDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQGCPCNYR 1462
                + L+EK+   H                   A+H  +V+   +    PV G PCN+R
Sbjct: 1211 TAVGQMLDEKMSLCH-------------------ARHASKVNQHKQKFQAPVCGFPCNHR 1251

Query: 1463 ----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQSHPQSM 1518
                +   ++    + SQQA    Q  P R RQI  +++QP K      +     HPQ +
Sbjct: 1252 HLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGLRHPQIL 1309

Query: 1519 PHRKPVPHPNP 1529
              +K V   +P
Sbjct: 1310 HPKKAVSPVSP 1320


>gi|133892686 hypothetical protein LOC727830 [Homo sapiens]
          Length = 1347

 Score =  259 bits (663), Expect = 1e-68
 Identities = 281/972 (28%), Positives = 425/972 (43%), Gaps = 133/972 (13%)

Query: 1   MENILCFLNSYTETGLSPDSH--WLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNN 58
           MEN+   L   + + L+  S   W+ +D     +  LG F L L Y+       P   + 
Sbjct: 1   MENLPFPLKLLSASSLNAPSSTPWV-LDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSP 59

Query: 59  DIQKHQGRAKRRRKGGTFKGFP--DWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHD 116
             +K     +RRR  G  K       +  +R  EE   LLS L+S          G H D
Sbjct: 60  GKRKCPV-GRRRRPRGRMKNHSLRAGRECRRGLEETSDLLSQLQSL--------LGPHLD 110

Query: 117 TNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTP 176
              F +L  PDP   V +RA     Q  S E ++DAAP +S LAS              P
Sbjct: 111 KGDFGQLSGPDPPGEVGERAPDGASQS-SHEPMEDAAPILSLLASP------------DP 157

Query: 177 SATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
            A  P+DL  +P            SP  +TT     S S L    PP+P        P++
Sbjct: 158 QAKHPQDLASTP------------SPGPMTT-----SVSSLSASQPPEP------SLPLE 194

Query: 237 HSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHH 296
           H  P+       PPH  + +  SL P    +   +    STL        +  DS A   
Sbjct: 195 HPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRD--STLI-----TPSHCDSVALPL 247

Query: 297 GPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEF 356
           G  +P +L P +           ++ + P +  LGGS              +SH+++S  
Sbjct: 248 G-TVPQSLSPHE----------DLVASVPAISGLGGS--------------NSHVSAS-- 280

Query: 357 TWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLE 416
           + WQ  A+ S + N   S   ++ L+ H  E           +E  ++  LS D   ++ 
Sbjct: 281 SRWQETARTSCAFN---SSVQQDHLSRHPPETC--------QMEAGSLFLLSSDGQNVVG 329

Query: 417 RQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGK 476
            QV +     +W+E  +  GSF  ++ P   LNS RN+  S+  + D     PFW     
Sbjct: 330 IQVTETAKVNIWEEK-ENVGSFTNRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGEN 388

Query: 477 LEWQHIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLV-QRGHS--SMFVFFN 533
            +     Q+    + +++   + Y QLFWGLPSLHSESL     V  R ++  S    FN
Sbjct: 389 SKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFN 448

Query: 534 GITNT-SISHE---SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFR 589
            ++N   I  E   SP+L   QPLS    +  P   + PQ +   + Q ++ A  QS F 
Sbjct: 449 EMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFP 508

Query: 590 ALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQED 649
            L P+   LI+  GV     QN+ ++L   E  H EW +L++  E    LPS VQKSQ+ 
Sbjct: 509 VLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDV 568

Query: 650 FCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHES 709
           F    PN  L ++S       SI+P +FP+S E+R++LEQHI++ +IQ  WG   RI ES
Sbjct: 569 FSVSTPN--LPQESL-----TSILPENFPVSPELRRQLEQHIKKWIIQ-HWGNLGRIQES 620

Query: 710 LSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENV 769
           L L++ Q +    S ++    P   S+  G+     +K      R             ++
Sbjct: 621 LDLMQLQDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERD---------PCPHL 671

Query: 770 GNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRL----GQKQ 825
           G   G + + + +D        S  + +   +  +LE ++     +DSG  L     +  
Sbjct: 672 GQILGETPQNLSRD------MKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTH 725

Query: 826 LENALTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHC 885
           +EN L   + +   + NEG +P  V  SW +V Q + +   S++ +K  NL    S   C
Sbjct: 726 IENILKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPV---SNTHVKTSNLAAPKSGKAC 782

Query: 886 VDTSQEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLP 945
           V+T+Q +SFL    Q+ L AHI  F  +  WGLPL+VL+ I+ FK +   S S +    P
Sbjct: 783 VNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGP 842

Query: 946 SSATFISQGDSK 957
           SSAT  S   S+
Sbjct: 843 SSATCESGAGSE 854



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 120/497 (24%), Positives = 199/497 (40%), Gaps = 98/497 (19%)

Query: 1091 PPPHSIVDEVSQK------QTVLASRCSAELPIMQAGAGCESWDKRKSSFHNVDRLQGSR 1144
            PP  S+  +V  K      +++LAS   A     +A  G  SW+  +         +G  
Sbjct: 864  PPMASLRKQVLTKASDHMPESLLASS-PAWKQFQRAPRGIPSWNDHEPLKPPPAGQEGRW 922

Query: 1145 KTFPVTNALQSQTRNNLT----TSKSG--------------SCSLTNVKASTSNETEIFP 1186
             + P+T +L   T+ + +    +SK+G              +C L N++A TS +   F 
Sbjct: 923  PSKPLTYSLTGSTQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQA-TSEDVHGFE 981

Query: 1187 ----------PRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTD 1224
                      PR+SV QDP+   L  +++S+ +  +  +  +QPQ             + 
Sbjct: 982  APGTSKSSLHPRVSVSQDPRKLCLMEEVVSEFEPGMATKSETQPQVCAAVVLLPDGQASV 1041

Query: 1225 MSFALDNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQ 1283
            +  A +NL S+    + Q + +G+M  SQ +H  +     ++   +EPR P C    K Q
Sbjct: 1042 VPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVH-EEPRKPNCQGSCKSQ 1100

Query: 1284 VTNFPPAVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLK 1341
               FPP        +P   + +    GL T Q    RK+   H     ++L SK      
Sbjct: 1101 RPMFPPIHKSEKFRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK----- 1155

Query: 1342 TQPPPENLFRKWMKTSLQW-FNKPSISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTT 1400
             QPP  + F + +K   QW F+K         +  +K     SCV          ++ + 
Sbjct: 1156 -QPPSVSPFGENIKQIFQWIFSKKKSKPAPVTAESQKTVKNRSCV----------YSSSA 1204

Query: 1401 EAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQG 1456
            EAQ +     + L+EK+   H                   A+H  +V+   +    PV G
Sbjct: 1205 EAQGLMTAVGQMLDEKMSLCH-------------------ARHASKVNQHKQKFQAPVCG 1245

Query: 1457 CPCNYR----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQ 1512
             PCN+R    +   ++    + SQQA    Q  P R RQI  +++QP K      +    
Sbjct: 1246 FPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGL 1303

Query: 1513 SHPQSMPHRKPVPHPNP 1529
             HPQ +  +K V   +P
Sbjct: 1304 RHPQILHPKKAVSPVSP 1320


>gi|169174618 PREDICTED: family with sequence similarity 75, member
           A4 isoform 2 [Homo sapiens]
          Length = 1272

 Score =  259 bits (662), Expect = 1e-68
 Identities = 264/883 (29%), Positives = 392/883 (44%), Gaps = 127/883 (14%)

Query: 86  QREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHFRRLLCPDPVCRVCKRATADIQQLLS 145
           +R  EE   LLS L+S          G H D   F +L  PDP   V +RA     Q  S
Sbjct: 13  RRGLEETSDLLSQLQSL--------LGPHLDKGDFGQLSGPDPPGEVGERAPDGASQS-S 63

Query: 146 WESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLI 205
            E ++DAAP +SPLAS              P A  P+DL  +P            SP  +
Sbjct: 64  HEPMEDAAPILSPLASP------------DPQAKHPQDLASTP------------SPGPM 99

Query: 206 TTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEAS 265
           TT     S S L    PP+P  PL+   P    PP   P P   PH  + +  SL P   
Sbjct: 100 TT-----SVSSLSASQPPEPSLPLEHPSP---EPPALFPHP---PHTPDPLACSLPPPKG 148

Query: 266 LSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPIPSALPPEDCTVTQSKSSLTILKTFP 325
            +   +    STL        +  DS A   G    S  P ED           ++ + P
Sbjct: 149 FTAPPLRD--STLITP-----SHCDSVAFPLGTVPQSLSPHED-----------LVASVP 190

Query: 326 EMLSLGGSGGSSTSAPTIKGIDHSHLASSEFTWWQPHAKDSFSSNFVPSDFMEELLTLHS 385
            +  LGGS              +SH+++S  + WQ  A+ S + N   S   ++ L+ H 
Sbjct: 191 AISGLGGS--------------NSHVSAS--SRWQETARTSCAFN---SSVQQDHLSRHP 231

Query: 386 SEAFLGGHSVANLIEPVNISFLSHDILALLERQVKKRGDFLMWKENGKKPGSFPKQLRPN 445
            E           +E  ++  LS D   ++  QV +     +W+E  +  GSF  ++ P 
Sbjct: 232 PETCQ--------MEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEK-ENVGSFTNRMTPE 282

Query: 446 YQLNSSRNMLTSIAVKHDLAESFPFWASKGKLEWQHIHQQPPHSKCFEDHLEQKYVQLFW 505
             LNS RN+  S+  + D     PFW      +     Q+    + +++   + Y QLFW
Sbjct: 283 KHLNSLRNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKLSDPRLWQESFWKNYSQLFW 342

Query: 506 GLPSLHSESLHPTVLV-QRGHS--SMFVFFNGITNTS-ISHE---SPVLPPPQPLSLPST 558
           GLPSLHSESL     V  R ++  S    FN ++N   I  E   SP+L   QPLS    
Sbjct: 343 GLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHLGP 402

Query: 559 QPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIRICGVCFHRPQNEARSLLP 618
           +  P   + PQ +   + Q ++ A  QS F  L P+   LI+  GV     QN+ ++L  
Sbjct: 403 ECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNTGVACPASQNKVQALSL 462

Query: 619 SEINHLEWNVLQKVQESLWGLPSVVQKSQEDFCPPAPNPELVRKSFKVHVPISIIPGDFP 678
            E  H EW +L++  E    LPS VQKSQ+ F    PN  L ++S       SI+P +FP
Sbjct: 463 PETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPN--LPQESL-----TSILPENFP 515

Query: 679 LSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLRPQSKISELSVSERIHGPLNISLVE 738
           +S E+R++LEQHI++ +IQ  WG   RI ESL L++ + +    S ++    P   S+  
Sbjct: 516 VSPELRRQLEQHIKKWIIQ-HWGNLGRIQESLDLMQLRDESPGTSQAKGKPSPWQSSMST 574

Query: 739 GQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGYSQETVPKDHLLHGPETSSDKDLR 798
           G+     +K      R             ++G   G + + + +D        S  + + 
Sbjct: 575 GESSKEAQKVKFQLERD---------PCPHLGQILGETPQNLSRD------MKSFPRKVL 619

Query: 799 SNSERDLETHMMHLSGNDSGVRL----GQKQLENALTVRLSKKFEEINEGRMPGTVHSSW 854
             +  +LE ++     +DSG  L     +  +EN L   + +   + NEG +P  V  SW
Sbjct: 620 GVTSEELERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVRVRRSW 679

Query: 855 HSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTSQEISFLSSNKQKMLEAHIKTFRMRM 914
            +V Q + +   S++ +K  NL    S   CV+T+Q +SFL    Q+ L AHI  F  + 
Sbjct: 680 LAVNQALPV---SNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKH 736

Query: 915 LWGLPLKVLESIEIFKSKADLSTSFSHFDLPSSATFISQGDSK 957
            WGLPL+VL+ I+ FK +   S S +    PSSAT  S   S+
Sbjct: 737 RWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSE 779



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 105/437 (24%), Positives = 179/437 (40%), Gaps = 97/437 (22%)

Query: 1146 TFPVTNALQSQTRNNLTTSKSG--------------SCSLTNVKASTSNETEIFP----- 1186
            T+ +T ++Q        +SK+G              +C L N++A TS +   F      
Sbjct: 853  TYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQA-TSEDVHGFEAPGTS 911

Query: 1187 -----PRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTDMSFAL 1229
                 PR+SV QDP+   L  +++++ +  +  +  +QPQ             + +  A 
Sbjct: 912  KSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHAS 971

Query: 1230 DNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQVTNFP 1288
            +NL S+    + Q + +G+M  SQ +H  +     ++   +EPR P C    K Q   FP
Sbjct: 972  ENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVH-EEPRNPNCQGSCKSQRPMFP 1030

Query: 1289 PAVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLKTQPPP 1346
            P        +P   + +    GL T Q    RK+   H     ++L SK       QPP 
Sbjct: 1031 PIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK------QPPS 1084

Query: 1347 ENLFRKWMKTSLQWF-----NKPS-ISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTT 1400
             + F + +K   QW      +KP+ ++ E Q++           V+N  RV    ++ + 
Sbjct: 1085 VSPFGENIKQIFQWIFSKKKSKPAPVTAESQKT-----------VKNRSRV----YSSSA 1129

Query: 1401 EAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQG 1456
            EAQ +     + L++K+   H                   A+H  +V+   +    PV G
Sbjct: 1130 EAQGLMTAVGQMLDKKMSLCH-------------------ARHASKVNQHKQKFQAPVCG 1170

Query: 1457 CPCNYR----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQ 1512
             PCN+R    +   ++    + SQQA    Q  P R RQI  +++QP K      +    
Sbjct: 1171 FPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGL 1228

Query: 1513 SHPQSMPHRKPVPHPNP 1529
             HPQ +  +K V   +P
Sbjct: 1229 RHPQILHPKKAVSPVSP 1245


>gi|146231958 hypothetical protein LOC647060 [Homo sapiens]
          Length = 1347

 Score =  259 bits (662), Expect = 1e-68
 Identities = 282/968 (29%), Positives = 419/968 (43%), Gaps = 125/968 (12%)

Query: 1   MENILCFLNSYTETGLSPDSH--WLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNN 58
           MEN+   L   + + L+  S   W+ +D     +  LG F L L Y+       P   + 
Sbjct: 1   MENLPFPLKLLSASSLNAPSSTPWV-LDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSP 59

Query: 59  DIQKHQGRAKRRRKGGTFKGFP--DWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHD 116
             +K     +RRR  G  K       +   R  +E   LLS L+S          G H D
Sbjct: 60  GKRKCPV-GRRRRPRGRMKNHSLRAGRECPRGLQETSDLLSQLQSL--------LGPHLD 110

Query: 117 TNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTP 176
              F +L  PDP   V +RA     Q  S E ++DAAP +SPLAS              P
Sbjct: 111 KGDFGQLSGPDPPGEVGERAPDGASQS-SHEPMEDAAPILSPLASP------------DP 157

Query: 177 SATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
            A  P+DL  +P            SP  +TT     S S L    PP+P  PL+   P  
Sbjct: 158 QAKHPQDLASTP------------SPGPMTT-----SVSSLSASQPPEPSLPLEHPSP-- 198

Query: 237 HSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHH 296
             PP   P P   PH  + +  S  P    +   +    STL        +  DS A   
Sbjct: 199 -EPPALFPHP---PHTPDPLACSPPPPKGFTAPPLRD--STLITP-----SHCDSVALPL 247

Query: 297 GPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEF 356
           G    S  P ED           ++ + P +  LGGS              +SH+++S  
Sbjct: 248 GTVPQSLSPHED-----------LVASVPAISGLGGS--------------NSHVSAS-- 280

Query: 357 TWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLE 416
           + WQ  A+ S + N   S   ++ L+ H  E +         +E  ++  LS D    + 
Sbjct: 281 SRWQETARTSCAFN---SSVQQDHLSRHPPETYQ--------MEAGSLFLLSSDGQNAVG 329

Query: 417 RQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGK 476
            QV +     +W+E  +  GSF  ++ P   LNS RN+  S+  + D     PFW     
Sbjct: 330 IQVTETAKVNIWEEK-ENVGSFTDRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGEN 388

Query: 477 LEWQHIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLV-QRGHS--SMFVFFN 533
            +     Q+    + +++   + Y QLFWGLPSLHSESL     V  R ++  S    FN
Sbjct: 389 SKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFN 448

Query: 534 GITNTS-ISHE---SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFR 589
            ++N   I  E   SP+L   QP S    +  P   + PQ +   + Q ++ A  QS F 
Sbjct: 449 EMSNVCPIQRETTMSPLLFQAQPPSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFP 508

Query: 590 ALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQED 649
            L P+   LI+  GV     QN+ ++L   E  H EW +L++  E    LPS VQKSQ+ 
Sbjct: 509 VLSPAFPSLIKNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDV 568

Query: 650 FCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHES 709
           F    PN  L ++S       SI+P +FP+S E+R++LEQHI++ +IQ  WG   RI ES
Sbjct: 569 FSVSTPN--LPQESLT-----SILPENFPVSPELRRQLEQHIKKWIIQH-WGNLGRIQES 620

Query: 710 LSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENV 769
           L L++ + +    S ++    P   S+  G+     +K      R             ++
Sbjct: 621 LDLMQLRDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERD---------PCPHL 671

Query: 770 GNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQKQLENA 829
           G   G + + + +D      +          SER+L   +   SG+D      +  +EN 
Sbjct: 672 GQILGETPQNLSRDMKSFPRKVLGVTS--EESERNLRKPLRSDSGSDLLRCTERTHIENI 729

Query: 830 LTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTS 889
           L   + +   + NEG +P  V  SW +V Q + +   S++ +K  NL    S   CV+T+
Sbjct: 730 LKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPV---SNTHVKTSNLAAPKSGKACVNTA 786

Query: 890 QEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLPSSAT 949
           Q +SFL    Q+ L AHI  F  +  WGLPL+VL+ I+ FK +   S S +    PSSAT
Sbjct: 787 QVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSAT 846

Query: 950 FISQGDSK 957
             S   S+
Sbjct: 847 CESGAGSE 854



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 101/431 (23%), Positives = 170/431 (39%), Gaps = 85/431 (19%)

Query: 1146 TFPVTNALQSQTRNNLTTSKSG--------------SCSLTNVKASTSN---------ET 1182
            T+ +T + Q        +SK+G              +C L N++A++ +           
Sbjct: 928  TYSLTGSTQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDMHGFEAPGTSK 987

Query: 1183 EIFPPRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTDMSFALD 1230
                PR+SV QDP+   L  +++++ +  +  +  +QPQ             + +  A +
Sbjct: 988  SSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASE 1047

Query: 1231 NLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQVTNFPP 1289
            NL S+    + Q + +G+M  SQ +H  +     ++   +EPR P C    K Q   FPP
Sbjct: 1048 NLVSQVPQGHLQSMPAGNMRASQELHDLMAARRSKLVH-EEPRNPNCQGSCKNQRPMFPP 1106

Query: 1290 AVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLKTQPPPE 1347
                    +P   + +    GL T Q    RK+   H     ++L SK       QPP  
Sbjct: 1107 IHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK------QPPSV 1160

Query: 1348 NLFRKWMKTSLQW-FNKPSISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTTEAQKIR 1406
            + F   +K   QW F+K         +  +K     SCV          ++ + EAQ + 
Sbjct: 1161 SHFGGNIKQFFQWIFSKKKSKPAPVTAESQKTVKNRSCV----------YSSSAEAQGLM 1210

Query: 1407 KDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQGCPCNYR 1462
                + L+EK+   H                   A+H  +V+   +    PV G PCN+R
Sbjct: 1211 TAVGQMLDEKMSLCH-------------------ARHASKVNQHKQKFQAPVCGFPCNHR 1251

Query: 1463 ----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQSHPQSM 1518
                +   ++    + SQQA    Q  P R RQI  +++QP K      +     HPQ +
Sbjct: 1252 HLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGLRHPQIL 1309

Query: 1519 PHRKPVPHPNP 1529
              +K V   +P
Sbjct: 1310 HPKKAVSPVSP 1320


>gi|223633941 hypothetical protein LOC389730 [Homo sapiens]
          Length = 1343

 Score =  259 bits (661), Expect = 2e-68
 Identities = 290/973 (29%), Positives = 418/973 (42%), Gaps = 139/973 (14%)

Query: 1   MENILCFLNSYTETGLSPDSH--WLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNN 58
           MEN+   L   + + L+  S   W+ +D     +  LG F L L Y+       P   + 
Sbjct: 1   MENLPFPLKLLSASSLNAPSSTPWV-LDIFLTLVFALGFFFLLLPYLSYFHCDDPPSPSP 59

Query: 59  DIQKHQGRAKRRRKGGTFKGFP--DWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHD 116
             +K     +RRR  G  K       +   R  EE   LLS L+S          G H D
Sbjct: 60  GKRKCPV-GRRRRPRGRMKNHSLRAGRECPRGLEETSDLLSQLQSL--------LGPHLD 110

Query: 117 TNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTP 176
              F +L  PDP   V +RA     Q  S E ++DAAP +SPLAS              P
Sbjct: 111 KGDFGQLSGPDPPGEVGERAPDGASQS-SHEPMEDAAPILSPLASP------------DP 157

Query: 177 SATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
            A  P+DL  +P            SP  +TT     S S L    PP+P  PL+   P  
Sbjct: 158 QAKHPQDLASTP------------SPGPMTT-----SVSSLSASQPPEPSLPLEHPSP-- 198

Query: 237 HSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHH 296
             PP   P P   PH  + +  S  P    +   +    STL        +  DS A   
Sbjct: 199 -EPPALFPHP---PHTPDPLACSPPPPKGFTAPPLRD--STLITP-----SHCDSVALPL 247

Query: 297 GPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEF 356
           G    S  P ED           ++ + P +  LGGS              +SH+++S  
Sbjct: 248 GTVPQSLSPHED-----------LVASVPAISGLGGS--------------NSHVSAS-- 280

Query: 357 TWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLE 416
           + WQ  A+ S + N   S   ++ L+ H  E           +E  ++  LS D   ++ 
Sbjct: 281 SRWQETARTSCAFN---SSVQQDPLSRHPPETCQ--------MEAGSLFLLSSDGQNVVG 329

Query: 417 RQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFPFWASKGK 476
            QV +     +W+E  +  GSF  Q+ P   LNS  N+  S+  + D     PFW     
Sbjct: 330 IQVTETAKVNIWEEK-ENVGSFTNQMTPEKHLNSLGNLAKSLDAEQDTTNPKPFWNMG-- 386

Query: 477 LEWQHIHQQPPHSKCFEDHLEQK-----YVQLFWGLPSLHSESLHPTVLV-QRGHS--SM 528
              ++  Q P   KC +  L Q+     Y QLFWGLPSLHSESL     V  R ++  S 
Sbjct: 387 ---ENSKQLPGPQKCSDPRLLQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSP 443

Query: 529 FVFFNGITNTS-ISHE---SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQP 584
              FN ++N   I  E   SP+L   QPLS       P   + PQ     + Q ++ A  
Sbjct: 444 PFLFNEMSNVCPIQRETTMSPLLFQAQPLS----HRQPFISSTPQFLPTPMAQAEAQAHL 499

Query: 585 QSPFRALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQ 644
           QS F  L P+   LI+  GV     QN+ ++L   E  H EW +L+K  E    LPS VQ
Sbjct: 500 QSSFPVLSPAFPSLIKNTGVACPASQNKVQALSLPETQHPEWPLLRKQLEGRLALPSRVQ 559

Query: 645 KSQEDFCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPR 704
           KSQ+ F    PN  L ++S       SI+P +FP+S E+R++LEQHI++ +IQ  WG   
Sbjct: 560 KSQDVFSVSTPN--LPQESLT-----SILPENFPVSPELRRQLEQHIKKWIIQH-WGNLG 611

Query: 705 RIHESLSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNML 764
           RI ESL L++ + +    S ++    P   S   G+     +K      R          
Sbjct: 612 RIQESLDLMQLRDESPGTSQAKGKPSPWQSSTSTGESSKEAQKVKFQLERDL-------- 663

Query: 765 SMENVGNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVRLGQK 824
              ++G   G + + + +D      +          SER+L   +   SG+D      + 
Sbjct: 664 -CPHLGQILGETPQNLSRDMKSFPRKVLGVTS--EESERNLRKPLRSDSGSDLLRCTERT 720

Query: 825 QLENALTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDH 884
            +EN L   + +   + NEG +P  V  SW +V Q + +   S++ +K  NL    S   
Sbjct: 721 HIENILKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPV---SNTHVKTSNLAAPKSGKA 777

Query: 885 CVDTSQEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDL 944
           CV+T+Q +SFL    Q+ L AHI  F  +  WGLPL+VL+ I+ FK +   S S +    
Sbjct: 778 CVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAG 837

Query: 945 PSSATFISQGDSK 957
           PSSAT  S   S+
Sbjct: 838 PSSATCESGAGSE 850



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 105/432 (24%), Positives = 172/432 (39%), Gaps = 87/432 (20%)

Query: 1146 TFPVTNALQSQTRNNLTTSKSG--------------SCSLTNVKASTSNETEIFP----- 1186
            T+ +T + Q        +SK+G              +C L N++A TS +   F      
Sbjct: 924  TYSLTGSTQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQA-TSEDVHGFEAPGTS 982

Query: 1187 -----PRISVPQDPKSSYLKNQMLSQLK--LVQRKHSQPQ----------SHFTDMSFAL 1229
                 PR+SV QDP+   L  +++S+ +  +  +  +QPQ             + +  A 
Sbjct: 983  KSSLHPRVSVSQDPRKLCLMEEVVSEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHAS 1042

Query: 1230 DNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQEPRVPTCVLQ-KCQVTNFP 1288
            +NL S+    + Q + +G+M  SQ +H  +     ++ Q +EPR P C    K Q   FP
Sbjct: 1043 ENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVQ-EEPRNPNCQGSCKSQRPMFP 1101

Query: 1289 PAVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSLPVHNKTSGEVLGSKSSPTLKTQPPP 1346
            P        +P   + +    GL T Q    RK+   H     ++L SK       QPP 
Sbjct: 1102 PIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKK------QPPS 1155

Query: 1347 ENLFRKWMKTSLQW-FNKPSISYEEQESSWEKGSSLSSCVQNIGRVIRAAFTGTTEAQKI 1405
             + F + +K   QW F+K         +  +K     SCV          ++ + EAQ +
Sbjct: 1156 VSHFGENIKQFFQWIFSKKKSKPAPVTAESQKTVKNRSCV----------YSSSAEAQGL 1205

Query: 1406 RKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGKAQHNPEVHVRAE----PVQGCPCNY 1461
                 + L++K+   H                   A H  +V+   +    PV G PCN+
Sbjct: 1206 MTAVGQMLDKKMSLCH-------------------AHHASKVNQHKQKFQAPVCGFPCNH 1246

Query: 1462 R----APSCKVTRTKSCSQQAIFVGQNYPTRIRQIIDKDRQPQKVEAFKGKILCQSHPQS 1517
            R    +   ++    + SQQA    Q  P R RQI  +++QP K      +     HPQ 
Sbjct: 1247 RHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQI--RNQQPLKSVRCNNEQWGLRHPQI 1304

Query: 1518 MPHRKPVPHPNP 1529
            +  +K V   +P
Sbjct: 1305 LHPKKAVSPVSP 1316


>gi|155029550 chromosome 9 open reading frame 79 [Homo sapiens]
          Length = 1445

 Score =  199 bits (507), Expect = 1e-50
 Identities = 376/1565 (24%), Positives = 561/1565 (35%), Gaps = 276/1565 (17%)

Query: 1    MENILCFLNSYTETGLSPDSHWLDIDPNFICLSGLGLFILYLFYVVLTLYSSPTEKNNDI 60
            ME +L  L S + T LSP S    +D     + GL L  L L YV     S P  +    
Sbjct: 42   MEKMLFPLKSPSATWLSPSSTPWMMDFILTSVCGLVLLFLLLLYVHSDPPSPPPGRKRSS 101

Query: 61   QKHQGRAKRRRKGGTFKGFPDWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHF 120
            ++ Q     R +          +   RE EE R L  LL+S                 H 
Sbjct: 102  REPQRERSGRSRSRKISALKACRILLRELEETRDLNYLLES-----------------HL 144

Query: 121  RRL---------LCPDPVCRVCKRATADIQQLLSWESLKDAAP-SVSPLASSASATESSF 170
            R+L         L  DP+  VCK   A   Q    + ++D +P S+SP A  A       
Sbjct: 145  RKLAGEGSSHLPLGGDPLGDVCKPVPAKAHQPHG-KCMQDPSPASLSPPAPPAP------ 197

Query: 171  TLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSP-SPLRDPLPPQPVSPL 229
             LAST          LSP P                T ++ F P S L    PP+P+ PL
Sbjct: 198  -LAST----------LSPGPM---------------TFSEPFGPHSTLSASGPPEPLLPL 231

Query: 230  DSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPI 289
                   H     + FP  P  H     S   P++SL+       GST C        P+
Sbjct: 232  KCPATQPH-----VVFPPSPQPHGPLASSPPPPDSSLAG---LQCGSTTC--------PV 275

Query: 290  DSCARHHGPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHS 349
               +  H   +P   PP                                    I G+  S
Sbjct: 276  PQSSPLHNQVLP---PP---------------------------------TRVISGLGCS 299

Query: 350  HLASSEFTWWQPHAKDSFSSNFVPSDFMEELLTLHSSEAFLGGHSVANLIEPVNISFLSH 409
                 +   W+  A     S +         L  H+SEA   G      +E    +F+  
Sbjct: 300  SDPIWDLYCWREAATTWGLSTYSHGKSQPRHLPDHTSEASFWGDPTPKHMEVGGCTFIHP 359

Query: 410  DILALLERQVKKRGDFLMWKENGKKPGSFPKQLRPNYQLNSSRNMLTSIAVKHDLAESFP 469
            D+  LLE  + KR    MW+E  +K    P               +TS+  + D+    P
Sbjct: 360  DVQKLLETLIAKRALMKMWQEKERKRADHPH--------------MTSLGKEWDITTLNP 405

Query: 470  FWASKGKLEWQHIHQQPPHSKCFEDHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHSSMF 529
            FW    + +     QQ   +    +HL+QK  QLFW LPSL+SESL  TV V R  SS  
Sbjct: 406  FWNVSTQPQQLPRPQQVSDATTVGNHLQQKRSQLFWDLPSLNSESLATTVWVSRNPSSQN 465

Query: 530  VFFNGI--TNTSISHESPV-------LPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKS 580
                 +   +TS+  E  V         PPQP  +   QP       PQ Q P L ++++
Sbjct: 466  AHSVPLDKASTSLPGEPEVEASSQLSQAPPQPHHM--AQPQHFTPAWPQSQPPPLAEIQT 523

Query: 581  LAQPQSPFRALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLP 640
             A    P  +L  S    IR CG  +   Q   +S++P+   +LEW  L+K  +    LP
Sbjct: 524  QAHLSPPVPSLGCSSPPQIRGCGASYPTSQERTQSVIPTGKEYLEWP-LKKRPKWKRVLP 582

Query: 641  SVVQKSQEDFCPPAPNPELVRKSFKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRW 700
            S+++KSQ     P  +    R +        I+PG    S E+ +   Q       ++  
Sbjct: 583  SLLKKSQAVLSQPTAHLPQERPASWSPKSAPILPG-VVTSPELPEHWWQGRNAIHQEQSC 641

Query: 701  GLPRRIHESLSLLRPQSKISELSVSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERS 760
            G P R+  S  LL+P  +      S+        +L+  Q  +   K      ++    S
Sbjct: 642  GPPSRLQASGDLLQPDGEFPGRPQSQA--EDTQQALLPSQPSDFAGKGRKDVQKTGFRSS 699

Query: 761  SNMLSMENVGNYQGYSQETVPKDHLLHGPETSSDKDLRSNSERDLETHMMHLSGNDSGVR 820
                    +G+  G      P      G  +    D    +E DL     + S + +   
Sbjct: 700  GRFSDKGCLGSKLGPD----PSRDQGSGRTSVKALDEDKEAEGDLRRSWKYQSVSSTPRD 755

Query: 821  LGQKQLENALTVRLSKKFEEINEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLV 880
              ++ LEN L + L++K  EI EG +P  V  SW   K  +    KS +  K   L +  
Sbjct: 756  PDKEHLENKLQIHLARKVGEIKEGWIPMPVRRSWLMAKCAVP---KSDTHRKPGKLASWR 812

Query: 881  SEDHCVDTSQEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFS 940
                 V+TSQE+SFL    Q++LE H+  F +R  WG  L+ LE I ++  +A  +  F 
Sbjct: 813  GGKAHVNTSQELSFLHPCTQQILEVHLVRFCVRHSWGTDLQSLEPINVWSGEAQ-APPFP 871

Query: 941  HFDLPSSATFISQGDSKDGVSKSRSRSTFQGEKLGTTSSVPILDRPHPVSSPVVQEGQGT 1000
                   A+++S+ +S                       VPI     P      Q G G 
Sbjct: 872  QSTFTPWASWVSRVES--------------------VPKVPIFLGKRP------QNGPG- 904

Query: 1001 LRRQFSDTDHDLIETDSKDGASTSLRRGTTDFQSEKLDSTSSFPILGHSYLVTSPVNQEK 1060
                              D  +TS                 S P +        P  +  
Sbjct: 905  ------------------DNRTTS----------------KSVPTVSGPLAAPPPEQEGV 930

Query: 1061 QGTLRREFSDTDNDLTESVRTTEDGRQTFLPPPHSIVDEVSQKQTVLAS---RCSAELPI 1117
            Q   R   S   +  +E+  T   GR    PP  S+V    Q +TVL S   +   E  +
Sbjct: 931  QRPPRGSQSADTHGRSEAFPTGHKGRGCSQPPTCSLVGRTWQSRTVLESGKPKPRLEGSM 990

Query: 1118 MQAGAGCESWDKRKS-------SFHNVDRLQGSRKTFPVTNALQSQ-----------TRN 1159
                AG E+W + +S       S   +  L    +     +ALQ+            T  
Sbjct: 991  GSEMAGNEAWLESESMSPGDPCSSRALQVLSIGSQWARAEDALQALKVGEKPPTWEVTLG 1050

Query: 1160 NLTTSKSGSCS----LTNVKASTSNETEIFPPRISVPQDPKSSYLKNQMLSQLKLVQRKH 1215
                + SGS       T    +T N +      + V QDP+  +LK Q++S++ L+ +  
Sbjct: 1051 ASVRASSGSVQEDLRSTGALGTTGNPSA---SSVCVAQDPEQLHLKAQVVSEIALIVQVD 1107

Query: 1216 SQPQ--------------------SHFTDMSFALDNLSSKDLLTNSQGISSGDMGTSQVV 1255
            S+ Q                        DM  A D L ++  L+ SQ +S  +M  SQ  
Sbjct: 1108 SEEQLPGRAPGILLQDGATGLCLPGRHMDMLTAADRLPTQAPLSTSQSVSGKNMTASQGP 1167

Query: 1256 HVHLEDSGIRVAQKQEPRVPTCVLQKCQVTNFPPAVNRVSPVRPKGGELDGGDAGLGTSQ 1315
               L   G    Q QEP  P     +        A    +  RP+ GE      G  TS+
Sbjct: 1168 CALLWKGGDSPGQ-QEPGSPKAKAPQKSQKTLGCADKGEAHRRPRTGEQGHRSKGPRTSE 1226

Query: 1316 RRRKSLPVHNKTSGEVLGSKSSPTL--KTQPPPENLFRKWMKTSLQWFNKPSISYEEQES 1373
               +S P   +  G+    K +     K Q PPE+ F++ +    Q  + P       E 
Sbjct: 1227 ASGRSHPAQAREIGDKQERKYNQLQLEKGQTPPESHFQRKISHHPQGLH-PRKGGTRWED 1285

Query: 1374 SWEKGSSLSSCVQNIGRVIRAAFTG--TTEAQKIRKDTREFLEEKLGHRHGIDITCPQEP 1431
              +KG   +   Q+ G      F      +A  I +   + L +KLG + G     P E 
Sbjct: 1286 VLQKGKPGADAFQSWGSGPPRQFMDCMADKAWTISRVVGQILVDKLGLQWG---RGPSE- 1341

Query: 1432 LSFPVGLGKAQHNPEVHVRAEPVQGCPCNYRAPSCKVTRTKSCSQQAIFVGQNYPTRIRQ 1491
                V   K     + +V +   +G   +      +  R  +CS +A   G + P + R 
Sbjct: 1342 ----VNRHKGDFRAQENVPSCCHRG---HCHQERSREMRALACSPKATPKGHHCPVKNRG 1394

Query: 1492 IIDKD 1496
            I D+D
Sbjct: 1395 IRDRD 1399


>gi|223468617 family with sequence similarity 75, member C1 [Homo
            sapiens]
          Length = 1188

 Score =  154 bits (389), Expect = 6e-37
 Identities = 153/516 (29%), Positives = 233/516 (45%), Gaps = 57/516 (11%)

Query: 544  SPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIRICG 603
            SP+L   QPLS    +  P   + PQ +   + Q ++ A  QS F  L P+ L  ++  G
Sbjct: 323  SPLLFQAQPLSHLGPESQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFLSPMKNTG 382

Query: 604  VCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQEDFCPPAPNPELVRKS 663
            V     QN+ ++L   E  H E  +L+K  E    LPS VQKSQ+ F    PN    R +
Sbjct: 383  VACPASQNKVQALSLPETQHPERPLLRKQLEGGLALPSRVQKSQDVFSVSTPNLPQERLT 442

Query: 664  FKVHVPISIIPGDFPLSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLRPQSKISELS 723
                   SI+P +FP+S E+ ++LEQ++ +R          RI ESL L++ Q ++   S
Sbjct: 443  -------SILPENFPVSPELWRQLEQYMGQR---------GRIQESLDLMQLQDELPGTS 486

Query: 724  VSERIHGPLNISLVEGQRCNVLKKSASSFPRSFHERSSNMLSMENVGNYQGYSQETVPKD 783
             ++    P   S   G+     +       R             ++G   G + +     
Sbjct: 487  QAKGKPRPWQSSTSTGESSKEAQTVKFQLERD---------PCPHLGQILGETPQ----- 532

Query: 784  HLLHGPETSSDKDLRSNSE---RDLETHMMHLSGNDSGVRLGQKQLENALTVRLSKKFEE 840
            +L  G E+   K L + SE   R+L   +   SG+D   R  +  +EN L   + +K  +
Sbjct: 533  NLSRGMESFPGKVLGATSEESERNLRKPLRSDSGSDLLRRTERNHIENILKAHMGRKLGQ 592

Query: 841  INEGRMPGTVHSSWHSVKQTMSLPEKSHSQIKHRNLVTLVSEDHCVDTSQEISFLSSNKQ 900
             NEG +P +V  SW +V Q   +   S++ +K  NL    S   CV+T+Q +SFL    Q
Sbjct: 593  TNEGLIPVSVRRSWLAVNQAFPV---SNTHVKTSNLAAPKSRKACVNTAQVLSFLELCTQ 649

Query: 901  KMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKADLSTSFSHFDLPSSATFISQGDSKDGV 960
            ++LEAHI  F  +  WGLPL+VL+ I+ F+ +   S S      PSS T  S   SK  V
Sbjct: 650  QVLEAHIVRFWAKHRWGLPLRVLKPIQCFQLEKVSSLSLIQLAGPSSDTCESGAGSKVEV 709

Query: 961  SKSRSRSTFQGEKLGTTSSVPILDRPH-------PVSSPVVQEGQGTLRRQFSDTDHDLI 1013
                  +T  GE    +    +L +P          SSP  ++ Q   R   S  DH  +
Sbjct: 710  ------ATLLGEPPMASLRKQVLTKPSVHMPERLQASSPACKQFQRAPRGIPSSNDHGSL 763

Query: 1014 E--TDSKDG-----ASTSLRRGTTDFQSEKLDSTSS 1042
            +  T  ++G       T   +G+T  QS  L + SS
Sbjct: 764  KAPTAGQEGRWPSKPLTYSLKGSTQ-QSRSLGAQSS 798



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 98/401 (24%), Positives = 159/401 (39%), Gaps = 73/401 (18%)

Query: 1167 GSCSLTNVKASTSNETEIFP----------PRISVPQDPKSSYLKNQMLSQLK--LVQRK 1214
            G+C   N++A TS +   F           PR+SV QDP+   L  + +S+ +  +  + 
Sbjct: 815  GTCMRANLQA-TSEDVRGFKAPGASKSSLLPRMSVSQDPRKLCLMEEAVSEFEPGMATKS 873

Query: 1215 HSQPQ----------SHFTDMSFALDNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGI 1264
             +QPQ             + +  A +NL+S+    + Q   +G+M  SQ +   +     
Sbjct: 874  ETQPQVSAAVVLLPDGQASVVPHASENLASQVPQGHLQSTPTGNMQASQELCDLMSARRS 933

Query: 1265 RVAQKQEPRVPTCVLQ-KCQVTNFPPAVNRVSPVRPKGGELDGGDAGLGTSQRR--RKSL 1321
             +  K EPR P C    K Q   FPP   R +  +P   + +    GL T Q    RK+ 
Sbjct: 934  NMGHK-EPRNPNCQGSCKSQSPMFPPTHKRENSRKPNLEKHEEMFQGLRTPQLTPGRKTE 992

Query: 1322 PVHNKTSGEVLGSKSSPTLKTQPPPENLFRKWMKTSLQW-FNKPSISYEEQESSWEKGSS 1380
                    ++L SK       QPP  + F + +K   +  F+K         +  +K   
Sbjct: 993  DTRQNEGVQLLPSKK------QPPSISHFGENIKQFFETIFSKKERKPAPVTAESQKTVK 1046

Query: 1381 LSSCVQNIGRVIRAAFTGTTEAQKIRKDTREFLEEKLGHRHGIDITCPQEPLSFPVGLGK 1440
              SCV          +  + EA+++     +  EE +   H                   
Sbjct: 1047 NRSCV----------YGSSAEAERLMTAVGQIPEENMSLCH------------------- 1077

Query: 1441 AQHNPEVHVRAE----PVQGCPCNYRAP----SCKVTRTKSCSQQAIFVGQNYPTRIRQI 1492
            A+H  +V+ + +    PV G PCN+R P      ++    + SQQA    Q+ P R RQI
Sbjct: 1078 ARHASKVNQQRQQFQAPVCGFPCNHRHPFYSDHSRMLSYAASSQQATLKNQSRPNRDRQI 1137

Query: 1493 IDKDRQPQKVEAFKGKILCQSHPQSMPHRKPVPHPNPTCRR 1533
              +D+QP K      +     HPQ +  +K V   +P   R
Sbjct: 1138 --RDQQPLKSVRCNNEQWGLRHPQLLLPKKAVSPVSPPQHR 1176



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 78/264 (29%), Positives = 105/264 (39%), Gaps = 56/264 (21%)

Query: 37  LFILYLFYVVLTLYS----------SPTEKNNDI--QKH---------QGRAKRRRKGGT 75
           +F L LF+++L  +S          SP ++   +  Q+H         +GR + R K  +
Sbjct: 33  VFALGLFFLLLPYFSYLRCDNPPSPSPRKRKRHLVSQRHLVSQCPTGRRGRPRGRMKNHS 92

Query: 76  FKGFPDWKSFQREEEEERKLLSLLKSFGPPVSCSPRGQHHDTNHFRRLLCPDPVCRVCKR 135
            +     +   R  EE   LLS L+S          G H +   F +L  PDP   V KR
Sbjct: 93  LRAC---RECPRGLEETWDLLSQLQSL--------LGPHLEKGDFGQLSGPDPPGEVGKR 141

Query: 136 ATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPP 195
            T D     S E ++DAAP VSPLAS    T+    LASTP   P    + S      P 
Sbjct: 142 -TPDGASRSSHEPMEDAAPIVSPLASPDPRTKHPQDLASTPPPGPMTTSVSSLSASQPPE 200

Query: 196 PPLIL---SPDLITTLADLFSPSPLRDPLPPQPVSPL--DSKFPIDHSPPQQLPFPLLPP 250
           P L+L   SP+            P   P PP    PL      P   +PP      LL P
Sbjct: 201 PSLLLERPSPE-----------PPALFPHPPHTPDPLACSPPPPKGFTPPPLRDSTLLTP 249

Query: 251 HH-------IERVESSLQPEASLS 267
            H       ++ V  SL P   L+
Sbjct: 250 SHCDSVALPLDTVPQSLSPREDLA 273


>gi|213512168 hypothetical protein LOC259308 [Homo sapiens]
          Length = 1335

 Score = 97.4 bits (241), Expect = 9e-20
 Identities = 114/424 (26%), Positives = 171/424 (40%), Gaps = 101/424 (23%)

Query: 397 NLIEPVNISFLSHDILALLERQVKKRGDFLMWKENGKKPGSFPKQLRPN----YQLNSSR 452
           +++ P ++ FLS ++L LLE  VKK   F  W    +   S  +QL PN    YQ  + +
Sbjct: 277 HMVLPAHLPFLSPEVLRLLEVHVKKWMHFQRWGLPRRVEESL-RQLMPNPPLYYQPGNDQ 335

Query: 453 ----NMLTSIAVKHDLAESFP---------------FWASKGKL---EWQHIHQQPPHSK 490
               N+  +  V     E+                 FW S+      E +H  QQ P+  
Sbjct: 336 PVSFNLKNTPQVSLHRFETISLQTWCSCVAGQPIQTFWVSEWSTMNPEQRHHCQQTPNPM 395

Query: 491 CFE------------------------DHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHS 526
                                        L+QKY QLF GLPSLHSESL  T +  +G  
Sbjct: 396 ALALPSPALKALSGPHPQSGGQDNDSGSDLQQKYSQLFCGLPSLHSESLVATFMGSQGLP 455

Query: 527 SMFVFFNGITNTSISHESPVLPPPQPLSLPSTQPLP--LPQTLPQGQSPHLTQVKSLAQP 584
            +              E+   PP +   L +    P  LP+T PQ   P      +   P
Sbjct: 456 KI--------------ENVPKPPLKDPFLFNELSFPQLLPKTSPQSAPPSSPLSPNWMSP 501

Query: 585 QSPFRALLPSPLFLIRICGVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQ 644
               RA +  P   +                   +E   LEW++LQ+  +  WG P+ +Q
Sbjct: 502 SDHQRAQINVPFLTL-------------------AEYEALEWHLLQRQLQLQWGWPAALQ 542

Query: 645 KSQE-------DFCPPAPNPELVRKSFKVHVPISIIPGDFPLSSE-VRKKLEQHIRRRLI 696
           +SQ        + C  A +PE    S +    IS++  +     E  RK LE HI+++LI
Sbjct: 543 RSQHTQCLMQHEPCGKAQSPETTTAS-QTGKSISVLTRELLFFPEHARKLLEFHIQKQLI 601

Query: 697 QRRWGLPRRIHESLSLL---RPQSKISELSVS-ERIHGPLNISLVEGQRCNVLKKSAS-- 750
           + RWGLP++I +S+ LL     Q  +S  S +   +  P  ++L     C+VL   A+  
Sbjct: 602 RHRWGLPQKIQQSIQLLLTSTDQQTVSSSSTALANVSIPQPVALEANGACDVLSPIAAPV 661

Query: 751 SFPR 754
           S PR
Sbjct: 662 SIPR 665



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 24/61 (39%), Positives = 38/61 (62%), Gaps = 2/61 (3%)

Query: 656 NPELVRKSFKVHVPISIIPGDFP-LSSEVRKKLEQHIRRRLIQRRWGLPRRIHESLSLLR 714
           NPE + +   + + + ++P   P LS EV + LE H+++ +  +RWGLPRR+ ESL  L 
Sbjct: 264 NPETLNRMHPMALHM-VLPAHLPFLSPEVLRLLEVHVKKWMHFQRWGLPRRVEESLRQLM 322

Query: 715 P 715
           P
Sbjct: 323 P 323



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 17/146 (11%)

Query: 25  IDPNFICLS-GLGLFILYLFYVVLTLYSSPTEKNNDIQKHQGRAKRRRKGGTFKGFPDWK 83
           + P F+    G  L+I    ++V+ +       ++++     R+  R      +   D  
Sbjct: 2   LSPTFVLWEVGYPLYIYGSIFIVIVIIWQVKRSHHELSSEPKRSCCRCHQKVRQRARDAA 61

Query: 84  SFQR-----EEEEERKLLSLLKSFG-PPVSCSPRGQHHDTNHFRRLLCPDPVCRVCKRAT 137
           S  R     E E+ +KLLS++KS G  P+  S           RR+LC DP C++C    
Sbjct: 62  STARRRSREEAEKPQKLLSIIKSQGWLPLERS----------VRRILCADPCCQICNSVA 111

Query: 138 ADIQQLLSWESLKDAAPSVSPLASSA 163
            +IQQLL  E+ + +     PL  S+
Sbjct: 112 LEIQQLLVGENNQISLTLSGPLQGSS 137



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 49/182 (26%), Positives = 80/182 (43%), Gaps = 17/182 (9%)

Query: 1160 NLTTSKSGSCSLTNVKASTSNETEIFPPRISVPQDPKSSYLKNQMLSQLKLVQRKHSQPQ 1219
            N++T KS   SL +   +   E  I P  +  P +P+  +LK Q+ + LK VQ+   Q  
Sbjct: 923  NISTQKSLE-SLNHQGETLLQELPIPPDTLPAP-NPEGVHLKEQLANDLKAVQQNQKQSN 980

Query: 1220 SHFTDMSFALDNLSSKDLLTNSQGISSGDMGTSQVVHVHLEDSGIRVAQKQ----EPRVP 1275
            S       A+   S+  +   SQ   SGDM  + +  V +E +  + + ++    EP+ P
Sbjct: 981  SK------AVPQGSAHSVSKISQ--PSGDMTEAHMPCVQVEANVNKPSLEEPCGPEPQSP 1032

Query: 1276 TCVLQKCQVTNFPPAVNRVSPVRPKGG-ELDGGDAGLGTSQRRRKSLPVHNKTSGEVLGS 1334
            +       V     A NR  P   K   +   GDAG G S  R +  P  ++    +L +
Sbjct: 1033 SKSKDPAHVPML--AGNREDPEETKAARDHREGDAGFGRSSTREERRPAEDQRPAGMLPN 1090

Query: 1335 KS 1336
            K+
Sbjct: 1091 KT 1092



 Score = 39.7 bits (91), Expect = 0.023
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 6/72 (8%)

Query: 889 SQEISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESIEIFKSKAD------LSTSFSHF 942
           ++E+ F   + +K+LE HI+   +R  WGLP K+ +SI++  +  D       ST+ ++ 
Sbjct: 578 TRELLFFPEHARKLLEFHIQKQLIRHRWGLPQKIQQSIQLLLTSTDQQTVSSSSTALANV 637

Query: 943 DLPSSATFISQG 954
            +P      + G
Sbjct: 638 SIPQPVALEANG 649



 Score = 35.8 bits (81), Expect = 0.34
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 21/106 (19%)

Query: 486 PPHS-KCFEDHLEQKYVQLFWGLPSLHSESLHPTVLVQRGHSSMFVFFNGITNTSISHES 544
           P H+ K  E H++++ ++  WGLP    +S+   +L      ++      + N SI    
Sbjct: 585 PEHARKLLEFHIQKQLIRHRWGLPQKIQQSIQ-LLLTSTDQQTVSSSSTALANVSI---- 639

Query: 545 PVLPPPQPLSLPST------QPLPLPQTLPQGQSPH-LTQVKSLAQ 583
                PQP++L +        P+  P ++P+   PH LTQVK++ Q
Sbjct: 640 -----PQPVALEANGACDVLSPIAAPVSIPR---PHLLTQVKAILQ 677



 Score = 32.7 bits (73), Expect = 2.8
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 14/73 (19%)

Query: 651 CPPAPNPEL--VRKSFKVHVPISIIPGDFPLSSE------------VRKKLEQHIRRRLI 696
           CP   N     V K F+  VP+       PL S+            +  KL  H+R++++
Sbjct: 841 CPQGNNESCTDVAKEFQPAVPVKGTMETLPLESQTHPTSPHSLQTHILTKLNFHLRKKVL 900

Query: 697 QRRWGLPRRIHES 709
           + +WG+P R  +S
Sbjct: 901 EIQWGIPIRARKS 913



 Score = 32.0 bits (71), Expect = 4.9
 Identities = 14/35 (40%), Positives = 21/35 (60%)

Query: 892 ISFLSSNKQKMLEAHIKTFRMRMLWGLPLKVLESI 926
           + FLS    ++LE H+K +     WGLP +V ES+
Sbjct: 284 LPFLSPEVLRLLEVHVKKWMHFQRWGLPRRVEESL 318


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 22/172 (12%)

Query: 150 KDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLA 209
           KDAAP++ PL+SS  AT S     + P   PP D   +P P   PP P + +P       
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARP--VPPPDNAATPLPATLPPSPPLATP------L 341

Query: 210 DLFSPSPLRDP----LPPQPVSPLDSKFPIDHSPPQQLP------FPLLPPHHI--ERVE 257
            L  PSP   P    LP  P +P     P   +PP Q P       P+  PH +    ++
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401

Query: 258 SSLQPEASLSLNTIFSFGSTLCQDISQ--AMNPIDSCARHHGPPIPSALPPE 307
           +   P A  SL    S GS   Q       M+P  + A    P  P++ PP+
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 50/174 (28%), Positives = 72/174 (41%), Gaps = 16/174 (9%)

Query: 159 LASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLR 218
           L  S   T++S T  S P++TPP+       P    P  L  SP L T+L+   + SPL 
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDS------PPLQAPLSLPASPPLQTSLSP--AVSPLS 481

Query: 219 DPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIER--VESSLQ-PEASLSLNTIFSFG 275
            PL   P+  L S     HSP   L   ++PP   +      SLQ P ASL+   + +  
Sbjct: 482 SPLTIHPLQALSSL--ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539

Query: 276 STLCQDISQAMNPIDSCARHHGP---PIPSALPPEDCTVTQSKSSLTILKTFPE 326
           S     +  A  P+ +      P   P P   PP   T    ++  +I    P+
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 38/106 (35%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 152 AAPSVSPLASSASATESSFTLASTPSATPPEDLILSPR-PKASPPP---PLILSPDLITT 207
           A+P VSP A+  S    S  LA+ P   PP      P  P A+PPP   P + +P L   
Sbjct: 681 ASPPVSPSATPPSQAPPS--LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738

Query: 208 LADLFSPSPLRDPLPPQPVSPLDSKFP--IDHSPPQQLPF-PLLPP 250
            +   SP       PP  V PL +  P  +  SPP  LP  PL  P
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 15/108 (13%)

Query: 152 AAPSVSPLASSASATESSFTLASTPSATP---------PEDLILSPRPKASPPPPLILSP 202
           A+ +  PL +  S        AS P  TP         P  L   P P  +PPP    +P
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE---TP 584

Query: 203 DLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
             I T      P+    PL   P  PL    P+   PPQ  P   LPP
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLS---PLATPPPQAPPXLALPP 629



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 37/123 (30%), Positives = 52/123 (42%), Gaps = 25/123 (20%)

Query: 152 AAPSVSPLASSASATESSFT--LASTPSATPPEDLILSP-RPKASPP-----------PP 197
           A+P +SPLA+ +    ++    L   P + PP   + +P  P ASPP           PP
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697

Query: 198 LILSPDLITTLADLFSP--SPLRDPLPPQPVSPLDS-KFPIDHSPPQQLPF-------PL 247
            + +P L    +   SP  SP   P PPQ   PL +    +  SPP   P        P 
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATP-PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756

Query: 248 LPP 250
           +PP
Sbjct: 757 VPP 759



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 45/172 (26%), Positives = 66/172 (38%), Gaps = 23/172 (13%)

Query: 175 TPSATPPEDLILSPRPKASPPP---PLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDS 231
           +P  TPP +   +P   A+PPP   P + SP L      L SP PL     P P +P   
Sbjct: 574 SPLTTPPPE---TPSSIATPPPQAPPALASPPL----QGLPSP-PLSPLATPPPQAPPXL 625

Query: 232 KFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFS-FGSTLCQDISQAMNPID 290
             P   +PP     P L P        S Q   +L+++ + + F       +    +P  
Sbjct: 626 ALPPLQAPPSPPASPPLSP----LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681

Query: 291 SCARHHGPPI-PSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAP 341
           S      PP+ PSA PP     + +   L +  + P    +  S      AP
Sbjct: 682 S------PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727



 Score = 31.2 bits (69), Expect = 8.3
 Identities = 15/40 (37%), Positives = 18/40 (45%)

Query: 547 LPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQS 586
           L PP P + PS Q LP P   P  Q+P       +  P S
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS 382



 Score = 31.2 bits (69), Expect = 8.3
 Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 3/46 (6%)

Query: 545 PVLPP---PQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSP 587
           P  PP   P  ++ P  Q  P  QT+P  Q PH     SL  P SP
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406



 Score = 31.2 bits (69), Expect = 8.3
 Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 7/100 (7%)

Query: 154 PSVSPLASSASATESSFTLASTPSA----TPPEDLILSPRPKASPPPPLILSPDLITTLA 209
           P+  P++ SA+       L + P      +PP  L +SP  K  P  P  L+   +  L 
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801

Query: 210 DLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLP 249
              +  P + P  P    P+    P+   PPQ  P    P
Sbjct: 802 SPPASFPGQAPFSPSASLPMS---PLATPPPQAPPVLAAP 838


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 58/198 (29%), Positives = 83/198 (41%), Gaps = 21/198 (10%)

Query: 150 KDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPL---ILSPDLIT 206
           KDAAP++ PL+SS  AT S    ++ PS + P  L   P P A+PP      + SP L  
Sbjct: 281 KDAAPALGPLSSSPLATPSP---SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337

Query: 207 TLADLFSPSPLRDPL-PPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEAS 265
           T +  F PSP   PL  P P +P     P   +PP     P L P        S Q   +
Sbjct: 338 THS--FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP----LATPSPQAPNA 391

Query: 266 LSLNTIFS-FGSTLCQDISQAMNPIDSCARHHGPPI-PSALPPEDCTVTQSKSSLTILKT 323
           L+++ + + F       +    +P  S      PP+ PSA PP     + +   L +  +
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPAS------PPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 324 FPEMLSLGGSGGSSTSAP 341
            P    +  S      AP
Sbjct: 446 PPASPPMSPSATPPPQAP 463



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 12/110 (10%)

Query: 152 AAPSVSPLASSASATESSFT--LASTPSATPPEDLI-------LSPRPKASPPPPLILSP 202
           A+P +SPLA+ +    ++    L   P + PP   +        SP    S  PP    P
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433

Query: 203 DLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQL--PFPLLPP 250
            L      +    P   P+ P    P  +  P+  +PP QL  P P  PP
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL-AAPPLQLAKPPPQAPP 482



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 7/104 (6%)

Query: 154 PSVSPLASSAS-ATESSFTLASTPSATPPEDLILSP-RPKASP----PPPLILSPDLITT 207
           P+  P++ SA+  +++  +LA+ P   PP      P  P A+P    PPPL   P  +  
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475

Query: 208 LADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPF-PLLPP 250
                 P+    PL   P  P         SP   LP  PL  P
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519


>gi|149363676 hypothetical protein LOC404770 [Homo sapiens]
          Length = 182

 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 48/136 (35%), Positives = 58/136 (42%), Gaps = 29/136 (21%)

Query: 90  EEERKLLSLLKSFGPPVSCSPRGQHHDTNHFRRLLCPDPVCRVCKRATADIQQLLSWESL 149
           EE   LLS L+S          G H D   F +L  P+P   V KRA  D     S E +
Sbjct: 41  EETWDLLSQLQSL--------LGTHLDKGDFGQLSGPEPPGEVGKRAP-DGASRSSLEPM 91

Query: 150 KDAAPSVSPLASSASATESSFTLASTPS-------------ATPPEDLILSPRPKASPP- 195
           +DAAP +  LAS     +    LASTPS             + PPE  +L  RP   PP 
Sbjct: 92  EDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPPA 151

Query: 196 ------PPLILSPDLI 205
                  PLIL P L+
Sbjct: 152 LFLTHHTPLILWPALL 167


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 53/178 (29%), Positives = 73/178 (41%), Gaps = 26/178 (14%)

Query: 143 LLSWESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSP 202
           +LS +  +D     S  + + S++   +   + PS TP E     P+ + SPPP   L P
Sbjct: 155 VLSEDRREDRRADTSAHSKAGSSSPEPW---ARPSCTPQEGGCPRPKERESPPPS-ALQP 210

Query: 203 DLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQ- 261
             +  LA   SP P   PLPP P  PL    P   SPP     P  PP  +   + SL  
Sbjct: 211 VQLPRLA--LSPPPPAPPLPPPP--PLAQVAPSPPSPPP----PPRPPPTLSASDPSLDF 262

Query: 262 -PEASLSLNTIFSFGSTLCQ---DISQAMN---------PIDSCARHHGPPIPSALPP 306
                 + N I     TL Q    +S+A++         P+DS      PP P   PP
Sbjct: 263 LRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPP 320



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 39/144 (27%), Positives = 53/144 (36%), Gaps = 16/144 (11%)

Query: 543 ESPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIRIC 602
           ESP     QP+ LP     P P   P    P L QV     P SP     P P       
Sbjct: 201 ESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQV--APSPPSPPPPPRPPPTLSASDP 258

Query: 603 GVCFHRPQNEARSLLPSEINHLEWNVLQKVQESLWGLPSVVQKSQEDFC----------P 652
            + F R Q E  + +      L    L K+ E+L  L  ++  +  D            P
Sbjct: 259 SLDFLRAQQETANAIRELAGTLRQG-LAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPP 317

Query: 653 PAPNPELVRKSFKVHV---PISII 673
           P P P L   + KV +   P+S++
Sbjct: 318 PPPRPVLPPPAPKVEITPEPVSVV 341


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 51/174 (29%), Positives = 66/174 (37%), Gaps = 22/174 (12%)

Query: 154 PSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPL-----------ILSP 202
           P   P +    A   S  L  +P + PPE+  LSP P++SP  PL             SP
Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530

Query: 203 DLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSP------PQQLPFPLLPPHHIERV 256
            L T L+     SPL  P    P+SP   + P    P      P     P+ PP   E  
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP--EES 588

Query: 257 ESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPP--IPSALPPED 308
             S  PEAS  L   F             ++P    +R   PP   P + PPE+
Sbjct: 589 PMSPPPEAS-RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEE 641



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 48/162 (29%), Positives = 65/162 (40%), Gaps = 22/162 (13%)

Query: 175 TPSATPPEDLILSPRPKASPPPPLILSPDLITTLADL-FSPSPLRDPLPP----QPVSPL 229
           +P++ PPE   LSP P+  P  PL  +  L   L +   SP P   PL P     P SPL
Sbjct: 456 SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL 515

Query: 230 DSK--FPIDHSPPQ-QLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAM 286
           +     P + SPP   L  PL PP           PEAS  L+  F              
Sbjct: 516 EESPLSPPEESPPSPALETPLSPP-----------PEAS-PLSPPFEESPLSPPPEELPT 563

Query: 287 NPIDSCARHHGPP--IPSALPPEDCTVTQSKSSLTILKTFPE 326
           +P    +R   PP   P + PPE+  ++    +  +   F E
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 41/122 (33%), Positives = 52/122 (42%), Gaps = 15/122 (12%)

Query: 147 ESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASP-PPPLILSPDLI 205
           ES     P  SP++    A+        +P + PPE+  LSP P+AS   PP   SP   
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP--- 634

Query: 206 TTLADLFSPSPLRDPLPPQPVSPLDSKFPIDH--SPPQQLPFPLLPPHHIERVESSLQPE 263
                  SP P   P+ P P     S  P+    SPP +   PL PP   E   +S  PE
Sbjct: 635 ------MSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE-ESPLSPPP--EESPTSPPPE 685

Query: 264 AS 265
           AS
Sbjct: 686 AS 687



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 53/173 (30%), Positives = 69/173 (39%), Gaps = 21/173 (12%)

Query: 147 ESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPP-PPLILSPDLI 205
           ES     P   P +    A+  S     +P + PPE+  +SP P+AS   PP   SP   
Sbjct: 551 ESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP--- 607

Query: 206 TTLADLFSPSPLRDPLPPQPVSPLDSKFPIDH--SPPQQLPFPLLPPHHIER-----VES 258
                  SP P   PL P P +   S  P D   SPP +   P+ PP  + R     V S
Sbjct: 608 ------LSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE-ESPMSPPPEVSRLSPLPVVS 660

Query: 259 SLQP---EASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPIPSALPPED 308
            L P   E+ LS     S  S   +    +  P DS         P++ PPED
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPED 713



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 38/120 (31%), Positives = 52/120 (43%), Gaps = 9/120 (7%)

Query: 147 ESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLIT 206
           ES     P  SPL+    A+  S     +P + PPE+  +SP P+ S   PL     +++
Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL----PVVS 660

Query: 207 TLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASL 266
            L+     SPL  P    P SP      +  SPP +   P  PP   E   +S  PE SL
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRL--SPPPE-DSPTSPPP--EDSPASPPPEDSL 715



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 18/109 (16%)

Query: 152  AAPSVSPL--------ASSASATESSFT--LASTPSATPPEDLILSPRPKASPPPPLILS 201
            A P++SPL        A   S  ES     +  TP + PPE     P P     PP+IL 
Sbjct: 947  APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV----PPMILP 1002

Query: 202  PDLITTLADLFSPSP-LRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLP 249
            P   + +      SP L +PLPPQ    L       +SPP Q   P LP
Sbjct: 1003 PSPGSPVGPA---SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALP 1048



 Score = 34.3 bits (77), Expect = 0.98
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 147 ESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLI- 205
           ES     P  S L+     + +S     +P++ PPED ++S   + SP  PL   P L  
Sbjct: 677 ESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736

Query: 206 TTLADLFSPSPLRDPLPPQPVSP-LDSKFPIDHSPPQ 241
            +     SP P    L P+P  P L  +    H  PQ
Sbjct: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ 773



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 12/120 (10%)

Query: 151  DAAPSVSPLASSASATESSFTLASTPSATP--PEDLILSPRPKASPPPPLILSPDLITTL 208
            D+  S + L      T   F    TP A+   P+   L  RP+  PPP   L+P    + 
Sbjct: 2308 DSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ-EPPPAQALAPSP-PSH 2365

Query: 209  ADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQ---LPFPLLPPHHIERVESSLQPEAS 265
             D+F P    DP    P++P          PP+    LP   LP     RV +S Q ++S
Sbjct: 2366 PDIFRPGSYTDPYAQPPLTPRPQP-----PPPESCCALPPRSLPSDPFSRVPASPQSQSS 2420



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 544  SPVLPPPQPLSLPSTQPL---PLPQTLPQGQSPHLTQVKSLAQP 584
            SP  PP +PL    T+PL   P+P  LP   SP   + K  A+P
Sbjct: 4924 SPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967



 Score = 32.0 bits (71), Expect = 4.9
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 20/83 (24%)

Query: 186 LSPRPKASPPPP---------LILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPID 236
           LSPRP+  P  P          +  P    +L+ L     L +P  P P+SPL  + P+ 
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP-PLSPLPEELPLS 918

Query: 237 HS----------PPQQLPFPLLP 249
            S          PP  LP PL P
Sbjct: 919 PSGEPSLSPQLMPPDPLPPPLSP 941



 Score = 32.0 bits (71), Expect = 4.9
 Identities = 29/116 (25%), Positives = 40/116 (34%), Gaps = 18/116 (15%)

Query: 135  RATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASP 194
            ++  DI  LL  ES     P+      + S  +     A  P    P    L+P P + P
Sbjct: 4870 KSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPP 4929

Query: 195  PPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
              PL+  P             PL +P       P+ S  P+  SP    P P   P
Sbjct: 4930 TEPLVELP-----------TEPLAEP-------PVPSPLPLASSPESARPKPRARP 4967


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 40/114 (35%), Positives = 53/114 (46%), Gaps = 17/114 (14%)

Query: 147  ESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRP----KASPPPPLILSP 202
            +S  D+  S S  +SS+S++ SS + +S+ S +  ED     RP     ASPPP  +  P
Sbjct: 1028 DSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVP 1087

Query: 203  DLITTLADLFSPSPLR------DPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
                T A +  P P R       PLP Q  SP     P + SPP     PL PP
Sbjct: 1088 ----TPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSA---PLRPP 1134



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 17/86 (19%)

Query: 176 PSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPI 235
           P+ TPP+     P P   PPPP    P  + +L   + P      LPP+P  P       
Sbjct: 596 PAPTPPQQ----PPP---PPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGP------- 641

Query: 236 DHSPPQQLPFPLLPPHHIERVESSLQ 261
              PP + P P  PP HI    +SL+
Sbjct: 642 ---PPPEYPPPPPPPPHIYDFVNSLE 664



 Score = 32.0 bits (71), Expect = 4.9
 Identities = 49/207 (23%), Positives = 74/207 (35%), Gaps = 25/207 (12%)

Query: 154 PSVSPLA-SSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLF 212
           P  +P A ++A     S+T    P  + P D    P    +PPP     P          
Sbjct: 392 PPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPP----EPPEPGGGGGGG 447

Query: 213 SPSPLRDPL--PPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNT 270
            PSP R+ +   P+P SP  S  P   +  + +PF            SSL     + L  
Sbjct: 448 GPSPEREEVRTSPRPASPARSGSPAPETTNESVPF---------AQHSSLDSRIEMLLKE 498

Query: 271 IFSFGSTLCQDISQAMNPIDSC--ARHHGPPIPSALPPEDCTVTQSKSSLTILKTFPEML 328
             S  S L  D  +          AR  G  +PS      CT   + ++      F ++ 
Sbjct: 499 QRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPAN------FEDVA 552

Query: 329 SLG-GSGGSSTSAPTIKGIDHSHLASS 354
             G G  G++  +P   G + +   SS
Sbjct: 553 PTGSGEPGATRESPKANGQNQASPCSS 579


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 43/142 (30%), Positives = 59/142 (41%), Gaps = 12/142 (8%)

Query: 155 SVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLA----D 210
           S  P  ++A  T S+ T A   S+ PPE     P P A+ P P   S    TT A     
Sbjct: 183 SAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 211 LFSPSPLRDPLPPQ--PVSPLDSKFPIDHS----PPQQLPFPLLPPHHIERVESSLQPEA 264
             +P+PL    PP+   V P  S   +D S    PP+    P  P        SS  P+ 
Sbjct: 243 ATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQE 302

Query: 265 SLS--LNTIFSFGSTLCQDISQ 284
           + +  + T  S  +TL  D S+
Sbjct: 303 TTAAPITTPNSSPTTLAPDTSE 324



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 54/200 (27%), Positives = 72/200 (36%), Gaps = 24/200 (12%)

Query: 148 SLKDAAPSVSPLASSASA---TESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDL 204
           S+   AP  SP     +A   T S+ T A   S+ PPE     P P A+   P   S   
Sbjct: 150 SVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPP 209

Query: 205 ITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEA 264
            TT A      P   P PP   +P ++      +P    P PL          SS  PE 
Sbjct: 210 ETTAAP--PTPPATTPAPPSSSAPPETT-AAPPTPSATTPAPL---------SSSAPPET 257

Query: 265 SLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPIPSAL--PPEDCTVTQSKSSLTILK 322
           +    T     S    D S A  P ++ A    PP PSA    P      Q  ++  I  
Sbjct: 258 TAVPPT----PSATTLDPSSASAPPETTA---APPTPSATTPAPPSSPAPQETTAAPITT 310

Query: 323 TFPEMLSLGGSGGSSTSAPT 342
                 +L      +++APT
Sbjct: 311 PNSSPTTLAPDTSETSAAPT 330



 Score = 35.4 bits (80), Expect = 0.44
 Identities = 44/180 (24%), Positives = 64/180 (35%), Gaps = 29/180 (16%)

Query: 162 SASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPL 221
           + + + S  TLA   S  P +     P P A+ P P   S    TT A            
Sbjct: 144 NVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAA------------ 191

Query: 222 PPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQD 281
           PP P +   +  P   +PP+    P  PP       SS  P  + +     S        
Sbjct: 192 PPTPSATTQAP-PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS-------- 242

Query: 282 ISQAMNPIDSCARHHGPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAP 341
            +    P+ S A    PP  +A+PP     T   SS +     PE  +   +  ++T AP
Sbjct: 243 -ATTPAPLSSSA----PPETTAVPPTPSATTLDPSSAS---APPETTAAPPTPSATTPAP 294


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 43/142 (30%), Positives = 59/142 (41%), Gaps = 12/142 (8%)

Query: 155 SVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLA----D 210
           S  P  ++A  T S+ T A   S+ PPE     P P A+ P P   S    TT A     
Sbjct: 183 SAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 211 LFSPSPLRDPLPPQ--PVSPLDSKFPIDHS----PPQQLPFPLLPPHHIERVESSLQPEA 264
             +P+PL    PP+   V P  S   +D S    PP+    P  P        SS  P+ 
Sbjct: 243 ATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQE 302

Query: 265 SLS--LNTIFSFGSTLCQDISQ 284
           + +  + T  S  +TL  D S+
Sbjct: 303 TTAAPITTPNSSPTTLAPDTSE 324



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 54/200 (27%), Positives = 72/200 (36%), Gaps = 24/200 (12%)

Query: 148 SLKDAAPSVSPLASSASA---TESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDL 204
           S+   AP  SP     +A   T S+ T A   S+ PPE     P P A+   P   S   
Sbjct: 150 SVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPP 209

Query: 205 ITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEA 264
            TT A      P   P PP   +P ++      +P    P PL          SS  PE 
Sbjct: 210 ETTAAP--PTPPATTPAPPSSSAPPETT-AAPPTPSATTPAPL---------SSSAPPET 257

Query: 265 SLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPIPSAL--PPEDCTVTQSKSSLTILK 322
           +    T     S    D S A  P ++ A    PP PSA    P      Q  ++  I  
Sbjct: 258 TAVPPT----PSATTLDPSSASAPPETTA---APPTPSATTPAPPSSPAPQETTAAPITT 310

Query: 323 TFPEMLSLGGSGGSSTSAPT 342
                 +L      +++APT
Sbjct: 311 PNSSPTTLAPDTSETSAAPT 330



 Score = 35.4 bits (80), Expect = 0.44
 Identities = 44/180 (24%), Positives = 64/180 (35%), Gaps = 29/180 (16%)

Query: 162 SASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPL 221
           + + + S  TLA   S  P +     P P A+ P P   S    TT A            
Sbjct: 144 NVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAA------------ 191

Query: 222 PPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQD 281
           PP P +   +  P   +PP+    P  PP       SS  P  + +     S        
Sbjct: 192 PPTPSATTQAP-PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS-------- 242

Query: 282 ISQAMNPIDSCARHHGPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAP 341
            +    P+ S A    PP  +A+PP     T   SS +     PE  +   +  ++T AP
Sbjct: 243 -ATTPAPLSSSA----PPETTAVPPTPSATTLDPSSAS---APPETTAAPPTPSATTPAP 294


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 43/142 (30%), Positives = 59/142 (41%), Gaps = 12/142 (8%)

Query: 155 SVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLA----D 210
           S  P  ++A  T S+ T A   S+ PPE     P P A+ P P   S    TT A     
Sbjct: 183 SAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 211 LFSPSPLRDPLPPQ--PVSPLDSKFPIDHS----PPQQLPFPLLPPHHIERVESSLQPEA 264
             +P+PL    PP+   V P  S   +D S    PP+    P  P        SS  P+ 
Sbjct: 243 ATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQE 302

Query: 265 SLS--LNTIFSFGSTLCQDISQ 284
           + +  + T  S  +TL  D S+
Sbjct: 303 TTAAPITTPNSSPTTLAPDTSE 324



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 54/200 (27%), Positives = 72/200 (36%), Gaps = 24/200 (12%)

Query: 148 SLKDAAPSVSPLASSASA---TESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDL 204
           S+   AP  SP     +A   T S+ T A   S+ PPE     P P A+   P   S   
Sbjct: 150 SVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPP 209

Query: 205 ITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEA 264
            TT A      P   P PP   +P ++      +P    P PL          SS  PE 
Sbjct: 210 ETTAAP--PTPPATTPAPPSSSAPPETT-AAPPTPSATTPAPL---------SSSAPPET 257

Query: 265 SLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPIPSAL--PPEDCTVTQSKSSLTILK 322
           +    T     S    D S A  P ++ A    PP PSA    P      Q  ++  I  
Sbjct: 258 TAVPPT----PSATTLDPSSASAPPETTA---APPTPSATTPAPPSSPAPQETTAAPITT 310

Query: 323 TFPEMLSLGGSGGSSTSAPT 342
                 +L      +++APT
Sbjct: 311 PNSSPTTLAPDTSETSAAPT 330



 Score = 35.4 bits (80), Expect = 0.44
 Identities = 44/180 (24%), Positives = 64/180 (35%), Gaps = 29/180 (16%)

Query: 162 SASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPL 221
           + + + S  TLA   S  P +     P P A+ P P   S    TT A            
Sbjct: 144 NVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAA------------ 191

Query: 222 PPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQD 281
           PP P +   +  P   +PP+    P  PP       SS  P  + +     S        
Sbjct: 192 PPTPSATTQAP-PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS-------- 242

Query: 282 ISQAMNPIDSCARHHGPPIPSALPPEDCTVTQSKSSLTILKTFPEMLSLGGSGGSSTSAP 341
            +    P+ S A    PP  +A+PP     T   SS +     PE  +   +  ++T AP
Sbjct: 243 -ATTPAPLSSSA----PPETTAVPPTPSATTLDPSSAS---APPETTAAPPTPSATTPAP 294


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 67/298 (22%), Positives = 97/298 (32%), Gaps = 63/298 (21%)

Query: 141  QQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPL-- 198
            ++L S  S      S+SP +     ++++  L +TP ++   +   SP P  SP P    
Sbjct: 1096 KELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTP 1155

Query: 199  --ILSPDLITTLADLF------SPSPLRDPLP---------PQPVSPLDSKFPIDHS--- 238
               ++PD ITTL          +P P   P P         P P +       I HS   
Sbjct: 1156 DPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMI 1215

Query: 239  ------------------PPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQ 280
                              P    P P   PH      S++ P+ + +     +   T   
Sbjct: 1216 PDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMP 1275

Query: 281  DISQAMNPIDSCARHHGP-----------------PIPSALPPEDCT---VTQSKSSLTI 320
              +   +P  +      P                 P P+  P    T    T   SS  +
Sbjct: 1276 HPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPV 1335

Query: 321  LKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLASSEFTWWQPHAKDSFSSNFVPSDFME 378
            + T     SLG    S T APT+K   H  L    FT   PH   S      PS  +E
Sbjct: 1336 ITTVSLPTSLGTELSSPTLAPTVKPSLHPQLT---FTAPAPHTSTSQIPTLEPSPALE 1390



 Score = 34.3 bits (77), Expect = 0.98
 Identities = 51/188 (27%), Positives = 63/188 (33%), Gaps = 32/188 (17%)

Query: 154  PSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILS---PDLITTLAD 210
            PS SP     + T  S    +  SA   E    S  P  SPP P   S   PDLI T  D
Sbjct: 1011 PSASPGPPGPALTSDSSRELTPHSALTSE--ATSDAPDTSPPTPDPASRTNPDLILTSPD 1068

Query: 211  L------------FSPSPLRDPLP---------PQPVSPLDSKFPIDHSPPQQLPFPLL- 248
                          +P P   PLP         P   S + S  P     P+    P L 
Sbjct: 1069 FALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLD 1128

Query: 249  -PPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPIP-SALPP 306
              P+     E S  P+ S S +   +   T+  D    +NP       H P  P     P
Sbjct: 1129 TTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNP---TVTPHFPTTPHPTTTP 1185

Query: 307  EDCTVTQS 314
               T+T S
Sbjct: 1186 HPTTITHS 1193



 Score = 32.0 bits (71), Expect = 4.9
 Identities = 42/169 (24%), Positives = 61/169 (36%), Gaps = 13/169 (7%)

Query: 104  PPVSCSPRGQHHDTNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAAPSVSPLASSA 163
            P  +  P    H T      + PDP        T D        +  D  PS +P+ ++ 
Sbjct: 1283 PTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPD-PTTTPHPTTPD--PSSTPVITTV 1339

Query: 164  SATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPP 223
            S   S  T  S+P+  P     L P+   + P     +P   T+      PSP  +  P 
Sbjct: 1340 SLPTSLGTELSSPTLAPTVKPSLHPQLTFTAP-----APHTSTSQIPTLEPSPALESSPS 1394

Query: 224  Q--PVSPLDSKFPIDHSPPQ-QLPFPLLPPHHIERVESSL--QPEASLS 267
            +    + +D     D  PP+ Q P    PP H     S L   P+  LS
Sbjct: 1395 RSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLS 1443


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 10/146 (6%)

Query: 176 PSATPPEDLILSPRPKASPPPPLIL--SPDLITTLADLFSPSPLRDPLPPQPVSPLDSKF 233
           P   PP   I +P P  +PP PL+   +P    T+A + + +    P PP P +     F
Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819

Query: 234 PIDHSPPQ--QLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPIDS 291
           P  + PP     P P+ PP   ++     +P  S     +    S + Q  SQ   P   
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS----PLSPVPSVVKQIASQFPPPPTP 875

Query: 292 CARHHGP--PIPSALPPEDCTVTQSK 315
            A    P  P+P+ + P+     ++K
Sbjct: 876 PAMESQPLKPVPANVAPQSPPAVKAK 901



 Score = 35.4 bits (80), Expect = 0.44
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 11/135 (8%)

Query: 126 PDPVCRV-CKRATADIQQLLSWESLKDAAPSVSPLASSASATESSFTLASTPSATPPEDL 184
           P P+  +    +T  +  +++  +     P V P A    A  +S+   S P  TPP  +
Sbjct: 779 PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP-AKKQPAFPASYIPPSPP--TPPVPV 835

Query: 185 ILSPRPK-----ASPPP-PLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHS 238
                PK     A PPP PL   P ++  +A  F P P    +  QP+ P+ +      S
Sbjct: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV-APQS 894

Query: 239 PPQQLPFPLLPPHHI 253
           PP     P   P  I
Sbjct: 895 PPAVKAKPKWQPSSI 909



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 36/138 (26%), Positives = 54/138 (39%), Gaps = 11/138 (7%)

Query: 173 ASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSK 232
           A  P   PP+ L+  P P ++      ++P  + T A   +P+P   P   QP  P    
Sbjct: 771 APLPPQAPPKPLVTIPAPTSTK----TVAP--VVTQAAPPTPTPPVPPAKKQPAFPASYI 824

Query: 233 FPIDHSPPQQLPFPLLPPHH---IERVESSLQPEASL--SLNTIFSFGSTLCQDISQAMN 287
            P   +PP  +P P LP       +   S L P  S+   + + F    T     SQ + 
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK 884

Query: 288 PIDSCARHHGPPIPSALP 305
           P+ +      PP   A P
Sbjct: 885 PVPANVAPQSPPAVKAKP 902



 Score = 34.7 bits (78), Expect = 0.75
 Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 7/95 (7%)

Query: 156 VSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSPS 215
           +SP+ S      S F    TP A   + L   P   A   PP + +          + PS
Sbjct: 855 LSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK-------WQPS 907

Query: 216 PLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
            +  P P  P  P +S       PP  +P P  PP
Sbjct: 908 SIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 27/100 (27%)

Query: 508 PSLHSESLHPTVLVQRGHSSMFVFFNGITNTSISHESPVLPPPQPLS-LPSTQPLPLPQT 566
           P + S+S+ P +LV           NG+    +    P  PPP P S +   +P P   +
Sbjct: 690 PVMQSQSVKPQILVPP---------NGV----VPPPPPPPPPPTPGSAMAQLKPAPCAPS 736

Query: 567 LPQGQSP----------HLTQVKSLAQPQSPFRALLPSPL 596
           LPQ  +P          H+TQV   A P  P    +P+PL
Sbjct: 737 LPQFSAPPPPLKIHQVQHITQV---APPTPPPPPPIPAPL 773



 Score = 31.6 bits (70), Expect = 6.3
 Identities = 21/61 (34%), Positives = 23/61 (37%), Gaps = 5/61 (8%)

Query: 189 RPKASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLL 248
           RP  S  PPL   P ++T         PL  P PP P  P     P    PP  LP    
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPP-----PPPPPPPPPLPSQSA 654

Query: 249 P 249
           P
Sbjct: 655 P 655



 Score = 31.6 bits (70), Expect = 6.3
 Identities = 47/196 (23%), Positives = 71/196 (36%), Gaps = 37/196 (18%)

Query: 147  ESLKDAAPSVSPLASSASATESSFTLASTPSATP------PEDLIL------SPRPKASP 194
            + LK    +V+P +  A   +  +  +S P  +P      PE  ++      SP P   P
Sbjct: 881  QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940

Query: 195  PPPLILSPDLITT------LADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLL 248
            PPP   SP    +       +   SP   + P  PQ  S + S    +H  P++     L
Sbjct: 941  PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000

Query: 249  PPHHIERVES------SLQPEAS------LSLNTIFSFGSTLCQDISQAMNPI------D 290
                    ES      +L P A+      L+L+ + +    L Q    A  P+      D
Sbjct: 1001 VSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGV-NLPGVLQQGCVSAKAPVLSGRGKD 1059

Query: 291  SCARHHGPPIPSALPP 306
            S      PP  S  PP
Sbjct: 1060 SVVEFPSPPSDSDFPP 1075


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 84/347 (24%), Positives = 129/347 (37%), Gaps = 40/347 (11%)

Query: 104 PPVSCSPRGQHHDTNHFRRLLCPDPVCRVCKRATADIQQLLSWESLKDAA---PSVSPLA 160
           PP   SP        H + L+ P P+     +   ++QQ  + +    A    PS  PL 
Sbjct: 412 PPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLP 471

Query: 161 SSA---------SATESSFTLASTPSATPPEDLILSPRPKASPP-----PPLILSPDLIT 206
           +S          SA  S      +PS      L  SP P ASPP     PP  + P  + 
Sbjct: 472 ASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQ 531

Query: 207 TLADL-FSPSPL-RDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEA 264
           ++  L   P  L +  +  Q     + + P   +  Q LPF  LPP     V   +QP A
Sbjct: 532 SMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQ-LPFQTLPPPQTVAVNLQVQPPA 590

Query: 265 SLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGPPIPSALPPEDCTVTQ-----SKSSLT 319
            +    ++     +C++  +     D C R    P P  L P   TV +     S+  L 
Sbjct: 591 PVDPPVVYQV-EDVCEE--EMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLL 647

Query: 320 ILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHL----ASSEFTWWQPHAKDSFSSNFVPSD 375
                P + S+  S   S S P+   +    L    A++       H+      N  P  
Sbjct: 648 EQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQA 707

Query: 376 FMEELLTLHSSEAFLGGHSVANLIEPVNISFLSHDILALLERQVKKR 422
            ++  +  H  E F+    +   +EP  +S  S     L+E+ VKKR
Sbjct: 708 IVKPQILTHVIEGFV----IQEGLEPFPVSRSS----LLIEQPVKKR 746


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 55/188 (29%), Positives = 78/188 (41%), Gaps = 32/188 (17%)

Query: 153  APSVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLF 212
            AP+ SP+   ASA  S F   S P+  P +  +L+P   AS      L+P +      + 
Sbjct: 1542 APACSPVLVPASALASPF--PSAPNPAPAQASLLAPASSASQALATPLAP-MAAPQTAIL 1598

Query: 213  SPSPLRDPLPPQPV-SPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTI 271
            +PSP   PL P PV +P     P+  S   Q P P++ P       SS    +  S + +
Sbjct: 1599 APSP-APPLAPLPVLAPSPGAAPVLAS--SQTPVPVMAP-------SSTPGTSLASASPV 1648

Query: 272  FSFGSTLCQDISQAMNPIDSCARHHGPPIPSALPPEDCTVTQSKSSLTILKTFPEML-SL 330
             +    L    +Q M P          P+PS LP        S +S   L   P +  +L
Sbjct: 1649 PAPTPVLAPSSTQTMLP---------APVPSPLP--------SPASTQTLALAPALAPTL 1691

Query: 331  GGSGGSST 338
            GGS  S T
Sbjct: 1692 GGSSPSQT 1699



 Score = 37.7 bits (86), Expect = 0.088
 Identities = 52/219 (23%), Positives = 78/219 (35%), Gaps = 27/219 (12%)

Query: 154  PSVSPLASSASATESSFTLASTP----SATPPEDLILSPRPKASPPPPLILSPDLITTLA 209
            PS++P  +S SA+  +  LA+ P    S TP   L+L+P             P L +T+A
Sbjct: 1491 PSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSH--------VPGLNSTVA 1542

Query: 210  DLFSP-----SPLRDPLP--PQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQP 262
               SP     S L  P P  P P     S      S  Q L  PL P    +    +  P
Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSP 1602

Query: 263  EASLSLNTIFSFGSTLCQDISQAMNPIDSCARHHGP--------PIPSALPPEDCTVTQS 314
               L+   + +        ++ +  P+   A    P        P+P+  P    + TQ+
Sbjct: 1603 APPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQT 1662

Query: 315  KSSLTILKTFPEMLSLGGSGGSSTSAPTIKGIDHSHLAS 353
                 +    P   S      +   APT+ G   S   S
Sbjct: 1663 MLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLS 1701



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 148  SLKDAAPSVSPLASSASATESSFTLASTPSATPPEDLIL-SPRPKASPPPPLILSPDLIT 206
            S  + AP+ + L + AS+   +      P A P   ++  SP P  +P P L  SP    
Sbjct: 1561 SAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAP 1620

Query: 207  TLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLP 244
             LA   +P P+  P    P + L S  P+    P   P
Sbjct: 1621 VLASSQTPVPVMAP-SSTPGTSLASASPVPAPTPVLAP 1657



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 50/188 (26%), Positives = 74/188 (39%), Gaps = 29/188 (15%)

Query: 153  APSVSPLASSASATESSFTLAST--------PSATPPEDLILSPRPKASPPPPLILSPDL 204
            AP ++PL   A +  ++  LAS+        PS+TP   L  S  P  +P P  +L+P  
Sbjct: 1603 APPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLA-SASPVPAPTP--VLAPSS 1659

Query: 205  ITTLADLFSPSPLRDPLPPQPVSPLDSKFPI--DHSPPQQLPFPLLPPHHIERVESSLQP 262
              T+     PSPL  P   Q ++   +  P     SP Q L      P           P
Sbjct: 1660 TQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNP-------QGPFP 1712

Query: 263  EASLSLNTIFSFGSTLCQDISQA----MNPIDSCARHHGPPIPSA-----LPPEDCTVTQ 313
              +LSL    S   T  Q +S A    + P  + +    PP+  A      P    T+  
Sbjct: 1713 TQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAP 1772

Query: 314  SKSSLTIL 321
            + SS ++L
Sbjct: 1773 ASSSASLL 1780



 Score = 35.4 bits (80), Expect = 0.44
 Identities = 37/153 (24%), Positives = 60/153 (39%), Gaps = 15/153 (9%)

Query: 155  SVSPLASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITTLADLFSP 214
            S++P +S       + +LA  P   P + L L+P P  +P  P+  +P    TLA   S 
Sbjct: 1717 SLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSS 1776

Query: 215  SPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSF 274
            + L  P   Q ++   S  P+    P       L P       +S Q  AS + + + S 
Sbjct: 1777 ASLLAPASVQTLTL--SPAPVPTLGPAAAQTLALAP-------ASTQSPASQASSLVVSA 1827

Query: 275  GS------TLCQDISQAMNPIDSCARHHGPPIP 301
                    T+   +  + +  D+     GPP P
Sbjct: 1828 SGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSP 1860



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 16/174 (9%)

Query: 175  TPSATPPE-DLILSPRPK--ASPP--PPLILSPDLITTLADLFSPSPLRDPLPPQPVSPL 229
            TP+   P   L+ SP P+  AS P   PL +S  L    +    P P   P+P    SPL
Sbjct: 1367 TPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSS---LPGPASSPMPIPNSSPL 1423

Query: 230  DSKFPIDHSPPQQLPFPLLPPHHIERVESSLQPEASLSLNTIFSFGSTLCQDISQAMNPI 289
             S      S P     P+  P  +    S+       +  T+ + G  L   ++  + P+
Sbjct: 1424 ASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPV 1483

Query: 290  DSCARHHGPPIPSALPPEDCTVTQSKSSLTI-LKTFPEMLSLGGSGGSSTSAPT 342
               A     P P +L P     + S S+LT+ L T P + S    G     APT
Sbjct: 1484 VPAA-----PGPPSLAPSG--ASPSASALTLGLATAPSLSSSQTPGHPLLLAPT 1530



 Score = 32.0 bits (71), Expect = 4.9
 Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 8/54 (14%)

Query: 538  TSISHESPVLPPPQPLSLPSTQ----PLPLPQTLPQGQSPHLTQVKSLAQPQSP 587
            TS++  SPV P P P+  PS+     P P+P  LP   SP  TQ  +LA   +P
Sbjct: 1640 TSLASASPV-PAPTPVLAPSSTQTMLPAPVPSPLP---SPASTQTLALAPALAP 1689



 Score = 31.2 bits (69), Expect = 8.3
 Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 6/59 (10%)

Query: 545  PVLPPPQPLSLPSTQPL--PLPQTLPQGQSPHLTQVKSLAQPQSPFRALLPSPLFLIRI 601
            P   PP P+ LP  QP    LPQ LP   SP L  +   ++P +P  +L P+P   +R+
Sbjct: 1062 PASRPPGPVLLPPLQPNSGSLPQVLP---SP-LGVLSGTSRPPTPTLSLKPTPPAPVRL 1116


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 19/103 (18%)

Query: 152  AAPSVSPL----ASSASATESSFTLASTPSATPPEDLILSPRPKASPPPPLILSPDLITT 207
            A P   PL    +++++ T     L   P  TPP      P+P   PPPP    P     
Sbjct: 1429 AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALP----- 1483

Query: 208  LADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
                 SP PL  P P  P  P     P+   PP  +P P  PP
Sbjct: 1484 -----SPPPLVAPTPSSPPPP-----PLPPPPPPAMPSPPPPP 1516



 Score = 39.7 bits (91), Expect = 0.023
 Identities = 33/104 (31%), Positives = 40/104 (38%), Gaps = 17/104 (16%)

Query: 150  KDAAPSVSPLASSASATESSFTLASTPSATP---PEDLILSPRPKASPPPPLILSPDLIT 206
            KD +    P  + A+A      L   PSA     PE  +L  +P  +PPP          
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP---------- 1463

Query: 207  TLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
              A    P P   P PPQP  P  S  P+    P   P P LPP
Sbjct: 1464 --APTPQPQPPPPPPPPQPALP--SPPPLVAPTPSSPPPPPLPP 1503



 Score = 38.1 bits (87), Expect = 0.068
 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 9/132 (6%)

Query: 125  CPDPVCRVCKRATADIQQLLSWES-LKDAAPSVSPLASSASATESSFT---LASTPSATP 180
            CP P  R+ +    +++ L S+ S  +D+      L  S S+  S+     LA     + 
Sbjct: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTST 1418

Query: 181  PEDLILSPRPKASPPPPLILSPDLITTLADLFSPSPLRDPLPP--QPVSPLDSKFPIDHS 238
            P+   L+P      PPPL   P L +  ++     PL +  PP   P +P     P    
Sbjct: 1419 PDGPPLAPAAAVPGPPPL---PGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPP 1475

Query: 239  PPQQLPFPLLPP 250
            PP Q   P  PP
Sbjct: 1476 PPPQPALPSPPP 1487



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 18/53 (33%), Positives = 22/53 (41%)

Query: 535  ITNTSISHESPVLPPPQPLSLPSTQPLPLPQTLPQGQSPHLTQVKSLAQPQSP 587
            +  T  S   P LPPP P ++PS  P P P   P    P      S   P+ P
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 28/142 (19%)

Query: 534  GITNTSISHESPVLPPPQPLSLPSTQPLPLPQTLPQG--QSPHLTQVKSLAQPQSPFRAL 591
            G+  +     +P  PPP P       P P P + P+G   SP     K       P + L
Sbjct: 1028 GLIQSGPHQAAPPPPPPPP-------PPPAPASEPKGGLTSPIFCSTK-------PKKLL 1073

Query: 592  LPSPLFLIRICGVCFHRPQ-----------NEARSLLPSEINHLEWNVLQKVQESLWGLP 640
              S   L+R     F  P+           +E ++ +P++I  L    L  +  S    P
Sbjct: 1074 KTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIR-LNPRRLPDLVSSCRSRP 1132

Query: 641  SVVQKSQEDFCPPAPNPELVRK 662
            ++      DFCPP P P+  R+
Sbjct: 1133 ALSPLGDIDFCPPNPGPDGPRR 1154


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 35/119 (29%), Positives = 49/119 (41%), Gaps = 17/119 (14%)

Query: 141 QQLLSWESLKDAAPSVSPLA---------SSASATESSFTLASTPSATPPEDLILSPRPK 191
           ++ L WE  +  + + +P +           +SA+E     AS P+ TP +  I+     
Sbjct: 253 REQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLA 312

Query: 192 ASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
             PPPPL   P      A +  P P   P PP    PL S  P    PP  LP  + PP
Sbjct: 313 PPPPPPLPPGP----AQASVALPPPPGPPPPP----PLPSTGPPPPPPPPPLPNQVPPP 363


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 35/119 (29%), Positives = 49/119 (41%), Gaps = 17/119 (14%)

Query: 141 QQLLSWESLKDAAPSVSPLA---------SSASATESSFTLASTPSATPPEDLILSPRPK 191
           ++ L WE  +  + + +P +           +SA+E     AS P+ TP +  I+     
Sbjct: 253 REQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLA 312

Query: 192 ASPPPPLILSPDLITTLADLFSPSPLRDPLPPQPVSPLDSKFPIDHSPPQQLPFPLLPP 250
             PPPPL   P      A +  P P   P PP    PL S  P    PP  LP  + PP
Sbjct: 313 PPPPPPLPPGP----AQASVALPPPPGPPPPP----PLPSTGPPPPPPPPPLPNQVPPP 363


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,224,323
Number of Sequences: 37866
Number of extensions: 3766609
Number of successful extensions: 20993
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 430
Number of HSP's that attempted gapping in prelim test: 16705
Number of HSP's gapped (non-prelim): 3917
length of query: 1576
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1460
effective length of database: 13,855,062
effective search space: 20228390520
effective search space used: 20228390520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press