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Search of human proteins with 48476344
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48476344 regulating synaptic membrane exocytosis 3 [Homo
sapiens]
(308 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48476344 regulating synaptic membrane exocytosis 3 [Homo sapi... 607 e-174
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 387 e-108
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 346 2e-95
gi|154354981 regulating synaptic membrane exocytosis 2 isoform b... 346 2e-95
gi|33667061 regulating synaptic membrane exocytosis 4 [Homo sapi... 293 1e-79
gi|150378539 piccolo isoform 1 [Homo sapiens] 76 3e-14
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide... 71 1e-12
gi|13384594 protein kinase C, gamma [Homo sapiens] 57 2e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 55 6e-08
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 52 5e-07
gi|45504376 synaptotagmin VI [Homo sapiens] 52 7e-07
gi|14249614 synaptotagmin-like 1 [Homo sapiens] 51 1e-06
gi|28376627 synaptotagmin IX [Homo sapiens] 51 1e-06
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 50 3e-06
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] 50 3e-06
gi|4506067 protein kinase C, alpha [Homo sapiens] 49 4e-06
gi|238550198 synaptotagmin III [Homo sapiens] 49 6e-06
gi|238550196 synaptotagmin III [Homo sapiens] 49 6e-06
gi|14150054 synaptotagmin III [Homo sapiens] 49 6e-06
gi|39752671 synaptotagmin X [Homo sapiens] 49 6e-06
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 49 7e-06
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 49 7e-06
gi|110227631 synaptotagmin-like 3 [Homo sapiens] 49 7e-06
gi|209447073 synaptotagmin I [Homo sapiens] 47 2e-05
gi|5032139 synaptotagmin I [Homo sapiens] 47 2e-05
gi|209447070 synaptotagmin I [Homo sapiens] 47 2e-05
gi|38570146 synaptotagmin VII [Homo sapiens] 47 2e-05
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 47 3e-05
gi|211059429 synaptotagmin II [Homo sapiens] 47 3e-05
gi|31543670 synaptotagmin II [Homo sapiens] 47 3e-05
>gi|48476344 regulating synaptic membrane exocytosis 3 [Homo
sapiens]
Length = 308
Score = 607 bits (1566), Expect = e-174
Identities = 308/308 (100%), Positives = 308/308 (100%)
Query: 1 MFNGEPGPASSGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLT 60
MFNGEPGPASSGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLT
Sbjct: 1 MFNGEPGPASSGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLT 60
Query: 61 QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGT 120
QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGT
Sbjct: 61 QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGT 120
Query: 121 FIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARG 180
FIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARG
Sbjct: 121 FIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARG 180
Query: 181 LTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVI 240
LTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVI
Sbjct: 181 LTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVI 240
Query: 241 VWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLE 300
VWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLE
Sbjct: 241 VWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLE 300
Query: 301 SATSPSCS 308
SATSPSCS
Sbjct: 301 SATSPSCS 308
>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapiens]
Length = 1692
Score = 387 bits (995), Expect = e-108
Identities = 202/302 (66%), Positives = 237/302 (78%), Gaps = 10/302 (3%)
Query: 13 ASRNVVRSSSISGEICGSQQAGGGAGTTTA-------KKRRSSLGAKMVAIVGLTQWSKS 65
+ R++++S+S+SGE+ + G T KKRRSSL AK+VAIV ++ S+S
Sbjct: 1391 SGRSIMKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIV--SRRSRS 1448
Query: 66 TLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPT 125
T QL Q E KKL+S I+RSTETG+A EMR V RQ SRESTDGS NS SS+G IFP
Sbjct: 1449 TSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMV-RQPSRESTDGSINSYSSEGNLIFPG 1507
Query: 126 TRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKP 185
RLGA+SQFSDFLDGLGPAQ+VGRQTLATP MGD+ I + D+ GQLEVEVI AR LT KP
Sbjct: 1508 VRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKP 1567
Query: 186 GSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDY 245
GSKS PA Y+KVYLLENGAC+AKKKT++ +KT DPLYQQ+L+FDE PQGKVLQVIVWGDY
Sbjct: 1568 GSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDY 1627
Query: 246 GRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSP 305
GRMDHKCFMG+AQI+L+ELDLS+ V GWYKLFP SS+ D TL LTRR SQSSLES+T P
Sbjct: 1628 GRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGP 1687
Query: 306 SC 307
C
Sbjct: 1688 PC 1689
Score = 38.1 bits (87), Expect = 0.010
Identities = 29/112 (25%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Query: 170 QLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFD 229
QL V V++A L + + Y+K+Y L + + +K++TK KK +P + Q ++
Sbjct: 758 QLIVNVLQATDLPARVDGRPRNP-YVKMYFLPDRSDKSKRRTKTVKKILEPKWNQTFVYS 816
Query: 230 ----EGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLD-ELDLSAAVTGWYKL 276
+ ++L++ VW D R+ + + +I+++ E L WYKL
Sbjct: 817 HVHRRDFRERMLEITVW-DQPRVQEEESEFLGEILIELETALLDDEPHWYKL 867
>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
[Homo sapiens]
Length = 1349
Score = 346 bits (887), Expect = 2e-95
Identities = 173/249 (69%), Positives = 203/249 (81%), Gaps = 8/249 (3%)
Query: 68 QLPQ--PEGAT------KKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDG 119
QLPQ P+G KKLRS ++RSTETG+AVEMR+ +TRQ SRESTDGS NS SS+G
Sbjct: 1099 QLPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEG 1158
Query: 120 TFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEAR 179
IFP RL ++SQFSDFLDGLGPAQ+VGRQTLATP MGD+ + +MD+ GQLEVE+I AR
Sbjct: 1159 NLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRAR 1218
Query: 180 GLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQV 239
GL KPGSK+LPA Y+KVYLL+NG C+AKKKTK+ +KT +PLYQQ L F+E PQGKVLQ+
Sbjct: 1219 GLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQI 1278
Query: 240 IVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSL 299
IVWGDYGRMDHK FMG+AQI+LDEL+LS V GW+KLFP SS+ D TL LTRR SQSSL
Sbjct: 1279 IVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSL 1338
Query: 300 ESATSPSCS 308
ES+T PS S
Sbjct: 1339 ESSTGPSYS 1347
Score = 46.6 bits (109), Expect = 3e-05
Identities = 43/178 (24%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 106 ESTDGSTNSNSSDGTFIFPTTRL--GAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIA 163
ES+ S S D I T+ + G FL G +Q + R+T P + +
Sbjct: 693 ESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSSQSLSRRTTPFVPRVQIKLW 752
Query: 164 IMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQ 223
QL V ++ A+ L + + Y+K+Y L + + K++TK KKT +P +
Sbjct: 753 FDKVGHQLIVTILGAKDLPSREDGRPRNP-YVKIYFLPDRSDKNKRRTKTVKKTLEPKWN 811
Query: 224 QALLFD----EGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLD-ELDLSAAVTGWYKL 276
Q ++ + ++L++ +W D R+ + + +I+++ E L WYKL
Sbjct: 812 QTFIYSPVHRREFRERMLEITLW-DQARVREEESEFLGEILIELETALLDDEPHWYKL 868
>gi|154354981 regulating synaptic membrane exocytosis 2 isoform b
[Homo sapiens]
Length = 1163
Score = 346 bits (887), Expect = 2e-95
Identities = 173/249 (69%), Positives = 203/249 (81%), Gaps = 8/249 (3%)
Query: 68 QLPQ--PEGAT------KKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDG 119
QLPQ P+G KKLRS ++RSTETG+AVEMR+ +TRQ SRESTDGS NS SS+G
Sbjct: 913 QLPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEG 972
Query: 120 TFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEAR 179
IFP RL ++SQFSDFLDGLGPAQ+VGRQTLATP MGD+ + +MD+ GQLEVE+I AR
Sbjct: 973 NLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRAR 1032
Query: 180 GLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQV 239
GL KPGSK+LPA Y+KVYLL+NG C+AKKKTK+ +KT +PLYQQ L F+E PQGKVLQ+
Sbjct: 1033 GLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQI 1092
Query: 240 IVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSL 299
IVWGDYGRMDHK FMG+AQI+LDEL+LS V GW+KLFP SS+ D TL LTRR SQSSL
Sbjct: 1093 IVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSL 1152
Query: 300 ESATSPSCS 308
ES+T PS S
Sbjct: 1153 ESSTGPSYS 1161
Score = 38.5 bits (88), Expect = 0.008
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 14/104 (13%)
Query: 186 GSKSLPAT--------YIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFD----EGPQ 233
G+K LP+ Y+K+Y L + + K++TK KKT +P + Q ++ +
Sbjct: 558 GAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFR 617
Query: 234 GKVLQVIVWGDYGRMDHKCFMGMAQIMLD-ELDLSAAVTGWYKL 276
++L++ +W D R+ + + +I+++ E L WYKL
Sbjct: 618 ERMLEITLW-DQARVREEESEFLGEILIELETALLDDEPHWYKL 660
>gi|33667061 regulating synaptic membrane exocytosis 4 [Homo
sapiens]
Length = 269
Score = 293 bits (751), Expect = 1e-79
Identities = 143/232 (61%), Positives = 177/232 (76%)
Query: 74 GATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQ 133
G +++L+ I+RSTETG+AVEM SR RQ S ES + S NS S+G + L +++Q
Sbjct: 33 GDSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLASDAQ 92
Query: 134 FSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPAT 193
FSDFL +GPAQ VGRQTLAT PMGDV I + +R+GQLEV++I+ARGLT KPGSK+LPA
Sbjct: 93 FSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAA 152
Query: 194 YIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCF 253
YIK YLLENG C+AKKKTK+ +K+ DPLY Q LLF E PQGKVLQVIVWG+YGRM+ K F
Sbjct: 153 YIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERKQF 212
Query: 254 MGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSP 305
MG+A+++L+ELDL+ GWYKLFPTSS+ D G L R+ SQ SLES P
Sbjct: 213 MGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGP 264
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 76.3 bits (186), Expect = 3e-14
Identities = 56/187 (29%), Positives = 93/187 (49%), Gaps = 18/187 (9%)
Query: 103 GSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVG------RQTLATPP 156
GS S D +S+++ T +FP R+G Q +G P + G T
Sbjct: 4953 GSGYSVDSEGSSSTAGETNLFPIPRIGKMGQ-----NGQEPVKQPGVGVGLADTEAKTQV 5007
Query: 157 MGDVHIAI---MDRSG-QLEVEVIEARGLTPKPGSKS-LPATYIKVYLLENGAC--LAKK 209
MG++ IA+ M G QL VE+++ R +T K S LP Y+K+Y++ + KK
Sbjct: 5008 MGEIKIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVMNISTQKKVIKK 5067
Query: 210 KTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAA 269
KT++ + +P + + F P G LQ++++ + G+ K +G A I LD++DL
Sbjct: 5068 KTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMKKTLIGEACIWLDKVDLRKR 5127
Query: 270 VTGWYKL 276
+ W+KL
Sbjct: 5128 IVNWHKL 5134
Score = 55.5 bits (132), Expect = 6e-08
Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 22/174 (12%)
Query: 148 GRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLL------- 200
G + ++ P G++ + I G L + +++AR L P+ + ++KVYLL
Sbjct: 4686 GTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPR-DNNGYSDPFVKVYLLPGRGQVM 4744
Query: 201 --ENGACLAKKKTKMTKKTCDPLYQQALLFD----EGPQGKVLQVIVWGDYGRMDHKCFM 254
+N + K++TK +K+ +P + Q +++ E + K L+V VW DY R F+
Sbjct: 4745 VVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVW-DYDRFSSNDFL 4803
Query: 255 GMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS 308
G I L WY L + S+ S SS S SP S
Sbjct: 4804 GEVLIDLSSTSHLDNTPRWYPLKEQTE-------SIDHGKSHSSQSSQQSPKPS 4850
>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
[Homo sapiens]
Length = 1634
Score = 71.2 bits (173), Expect = 1e-12
Identities = 42/123 (34%), Positives = 69/123 (56%), Gaps = 6/123 (4%)
Query: 158 GDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKT 217
G+V ++I ++ +L + V+ RGL P Y+K+YLL + K+KTK+ +KT
Sbjct: 1506 GEVKLSISYKNNKLFIMVMHIRGLQLLQDGND-PDPYVKIYLLPDPQKTTKRKTKVARKT 1564
Query: 218 CDPLYQQALLFDEGPQG----KVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGW 273
C+P Y + L++D P+G + LQ+ V + G ++ +G I L ELDL+ TGW
Sbjct: 1565 CNPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWEN-VLLGEVNIRLRELDLAQEKTGW 1623
Query: 274 YKL 276
+ L
Sbjct: 1624 FAL 1626
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 57.0 bits (136), Expect = 2e-08
Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
Query: 170 QLEVEVIEARGLTPK-PGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLF 228
++ V V EAR L P P S P Y+K+ L+ + L K+KT+ K T +P++ + +F
Sbjct: 172 EIHVTVGEARNLIPMDPNGLSDP--YVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVF 229
Query: 229 D--EGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKL 276
+ G + L V VW D+ R FMG + EL L A V GWYKL
Sbjct: 230 NLKPGDVERRLSVEVW-DWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKL 277
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 55.5 bits (132), Expect = 6e-08
Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 22/174 (12%)
Query: 148 GRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLL------- 200
G + ++ P G++ + I G L + +++AR L P+ + ++KVYLL
Sbjct: 4686 GTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPR-DNNGYSDPFVKVYLLPGRGQVM 4744
Query: 201 --ENGACLAKKKTKMTKKTCDPLYQQALLFD----EGPQGKVLQVIVWGDYGRMDHKCFM 254
+N + K++TK +K+ +P + Q +++ E + K L+V VW DY R F+
Sbjct: 4745 VVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVW-DYDRFSSNDFL 4803
Query: 255 GMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS 308
G I L WY L + S+ S SS S SP S
Sbjct: 4804 GEVLIDLSSTSHLDNTPRWYPLKEQTE-------SIDHGKSHSSQSSQQSPKPS 4850
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 52.4 bits (124), Expect = 5e-07
Identities = 35/123 (28%), Positives = 64/123 (52%), Gaps = 7/123 (5%)
Query: 158 GDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKT 217
G V ++I R+G L + V+ + L + G+ P Y+K YLL + +K+KTK+++KT
Sbjct: 1561 GAVKLSISYRNGTLFIMVMHIKDLVTEDGAD--PNPYVKTYLLPDNHKTSKRKTKISRKT 1618
Query: 218 CDPLYQQALLFD----EGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGW 273
+P + + L++ E + + LQ+ V + F+G + L + +LS W
Sbjct: 1619 RNPTFNEMLVYSGYSKETLRQRELQLSVLSAES-LRENFFLGGVTLPLKDFNLSKETVKW 1677
Query: 274 YKL 276
Y+L
Sbjct: 1678 YQL 1680
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 52.0 bits (123), Expect = 7e-07
Identities = 34/105 (32%), Positives = 58/105 (55%), Gaps = 13/105 (12%)
Query: 162 IAIMDRSGQLEVEVIEARGLTPKPGSKSLPAT-----YIKVYLLENGACLAKKKTKMTKK 216
+ + +G+L + VI+ R L K++ T Y+KV LL +G L KKKT + K
Sbjct: 284 LCYLPTAGRLTLTVIKCRNL------KAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKN 337
Query: 217 TCDPLYQQALLFDEGPQG--KVLQVIVWGDYGRMDHKCFMGMAQI 259
T +P+Y +A++FD P+ +V +I DY R+ H +G+ ++
Sbjct: 338 TLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRV 382
>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
Length = 550
Score = 50.8 bits (120), Expect = 1e-06
Identities = 59/216 (27%), Positives = 93/216 (43%), Gaps = 36/216 (16%)
Query: 68 QLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPTTR 127
Q P+P+ A K S I + E G S D +S+SS + + +T
Sbjct: 191 QEPRPQQAQTKAASQILENGEEA-----------PGPDPSLDRMLSSSSSVSS-LNSSTL 238
Query: 128 LGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSG--QLEVEVIEARGLTPKP 185
G++ S G A+ A G VH A+ G +L V VI+ +GL
Sbjct: 239 SGSQMSLS------GDAE-------AVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAAR 285
Query: 186 GSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGP---QGKVLQVIVW 242
+S P Y+K YLL + +K+KT + K+ +P++ + L + QG+VL + VW
Sbjct: 286 RRRSDP--YVKSYLLPDKQ--SKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVW 341
Query: 243 GDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFP 278
+ F+G ++ LD D + T W L P
Sbjct: 342 -HRESLGRNIFLGEVEVPLDTWDWGSEPT-WLPLQP 375
Score = 35.0 bits (79), Expect = 0.084
Identities = 17/63 (26%), Positives = 39/63 (61%), Gaps = 4/63 (6%)
Query: 168 SGQLEVEVIEARGLTP-KPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQAL 226
SG+L V EAR L P + GS TY++ ++L + + ++++T++ +++ P++ +
Sbjct: 409 SGELHFWVKEARDLLPLRAGSLD---TYVQCFVLPDDSQASRQRTRVVRRSLSPVFNHTM 465
Query: 227 LFD 229
++D
Sbjct: 466 VYD 468
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 50.8 bits (120), Expect = 1e-06
Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 13/105 (12%)
Query: 162 IAIMDRSGQLEVEVIEARGLTPKPGSKSLPAT-----YIKVYLLENGACLAKKKTKMTKK 216
+ + +G+L + +I+AR L K++ T Y+KV L+ +G L K+KT +
Sbjct: 360 LCYLPTAGRLTITIIKARNL------KAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRN 413
Query: 217 TCDPLYQQALLFDEGPQG--KVLQVIVWGDYGRMDHKCFMGMAQI 259
T +P+Y +A++FD P+ ++ I DY R+ H +G+ Q+
Sbjct: 414 TLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQV 458
Score = 31.2 bits (69), Expect = 1.2
Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Query: 170 QLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLF 228
QL V++ +A L K S + Y+K+YLL + K +TK+ +KT +P++ + LF
Sbjct: 236 QLIVKIHKAVNLPAKDFSGTSDP-YVKIYLLPDRK--TKHQTKVHRKTLNPVFDEVFLF 291
>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 50.1 bits (118), Expect = 3e-06
Identities = 70/288 (24%), Positives = 110/288 (38%), Gaps = 29/288 (10%)
Query: 6 PGPASSGASRNVVRSSSISGEIC--GSQQAGGGAGTT---TAKKRRSSLGAKMVAIVGLT 60
PG SS A +S IS E S GT+ T RR++ G +A+ G +
Sbjct: 258 PGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRRNTSGTPSIAVSGTS 317
Query: 61 ---QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSS 117
S+S L L + + +IR + G + + + + ES D +S S
Sbjct: 318 LSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGAL----DKDSLEETEESIDALVSSQLS 373
Query: 118 DGTFIFP----TTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEV 173
T TT L + G ++ G L HI+ ++G L +
Sbjct: 374 TNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILL--------HISYCYKTGGLYI 425
Query: 174 EVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGP- 232
V R L K Y+K YLL + + K+KTK+ T +P + + L +
Sbjct: 426 FVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHT 484
Query: 233 --QGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFP 278
+ + LQ+ VW Y R F+G +I D + W+ L P
Sbjct: 485 QLETRTLQLSVW-HYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQP 531
Score = 35.8 bits (81), Expect = 0.049
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 141 LGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTP-KPGSKSLPATYIKVYL 199
L P Q+ G +T G + + G LEV + EA+ LT K G S +++K YL
Sbjct: 562 LPPEQLQGNKTFKK---GKKKESPVISGGILEVFIKEAKNLTAVKSGGTS--DSFVKGYL 616
Query: 200 LENGACLAKKKTKMTKKTCDPLYQQALLFD----EGPQGKVLQVIVWGDYGRMDHKCFMG 255
L + + K KT + KK+ +P + +F + + L++ +W D F+G
Sbjct: 617 LPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIW-DKEAFSSNIFLG 675
>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 50.1 bits (118), Expect = 3e-06
Identities = 70/288 (24%), Positives = 110/288 (38%), Gaps = 29/288 (10%)
Query: 6 PGPASSGASRNVVRSSSISGEIC--GSQQAGGGAGTT---TAKKRRSSLGAKMVAIVGLT 60
PG SS A +S IS E S GT+ T RR++ G +A+ G +
Sbjct: 258 PGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRRNTSGTPSIAVSGTS 317
Query: 61 ---QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSS 117
S+S L L + + +IR + G + + + + ES D +S S
Sbjct: 318 LSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGAL----DKDSLEETEESIDALVSSQLS 373
Query: 118 DGTFIFP----TTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEV 173
T TT L + G ++ G L HI+ ++G L +
Sbjct: 374 TNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILL--------HISYCYKTGGLYI 425
Query: 174 EVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGP- 232
V R L K Y+K YLL + + K+KTK+ T +P + + L +
Sbjct: 426 FVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHT 484
Query: 233 --QGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFP 278
+ + LQ+ VW Y R F+G +I D + W+ L P
Sbjct: 485 QLETRTLQLSVW-HYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQP 531
Score = 35.8 bits (81), Expect = 0.049
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 141 LGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTP-KPGSKSLPATYIKVYL 199
L P Q+ G +T G + + G LEV + EA+ LT K G S +++K YL
Sbjct: 562 LPPEQLQGNKTFKK---GKKKESPVISGGILEVFIKEAKNLTAVKSGGTS--DSFVKGYL 616
Query: 200 LENGACLAKKKTKMTKKTCDPLYQQALLFD----EGPQGKVLQVIVWGDYGRMDHKCFMG 255
L + + K KT + KK+ +P + +F + + L++ +W D F+G
Sbjct: 617 LPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIW-DKEAFSSNIFLG 675
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 49.3 bits (116), Expect = 4e-06
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 7/126 (5%)
Query: 154 TPPMGDVHIAIMDRSGQLEVEVIEARGLTPK-PGSKSLPATYIKVYLLENGACLAKKKTK 212
T G +++ +L V V +A+ L P P S P Y+K+ L+ + +K+KTK
Sbjct: 156 TEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDP--YVKLKLIPDPKNESKQKTK 213
Query: 213 MTKKTCDPLYQQALLFDEGPQGK--VLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAV 270
+ T +P + ++ F P K L V +W D+ R FMG + EL +
Sbjct: 214 TIRSTLNPQWNESFTFKLKPSDKDRRLSVEIW-DWDRTTRNDFMGSLSFGVSEL-MKMPA 271
Query: 271 TGWYKL 276
+GWYKL
Sbjct: 272 SGWYKL 277
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 48.9 bits (115), Expect = 6e-06
Identities = 41/155 (26%), Positives = 70/155 (45%), Gaps = 28/155 (18%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPAT-----YIKVYLLENGACLAKK 209
+G+++ ++ + +G+L V +I+A L K++ T Y+K L+ G L K+
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNL------KAMDLTGFSDPYVKASLISEGRRLKKR 485
Query: 210 KTKMTKKTCDPLYQQALLFDEGPQG--KVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLS 267
KT + K T +P Y +AL+FD P+ V I DY + H +G+ ++ D D
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
Query: 268 A-------------AVTGWYKLFPTSSVADSTLGS 289
V W++L +V T GS
Sbjct: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGS 580
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 48.9 bits (115), Expect = 6e-06
Identities = 41/155 (26%), Positives = 70/155 (45%), Gaps = 28/155 (18%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPAT-----YIKVYLLENGACLAKK 209
+G+++ ++ + +G+L V +I+A L K++ T Y+K L+ G L K+
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNL------KAMDLTGFSDPYVKASLISEGRRLKKR 485
Query: 210 KTKMTKKTCDPLYQQALLFDEGPQG--KVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLS 267
KT + K T +P Y +AL+FD P+ V I DY + H +G+ ++ D D
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
Query: 268 A-------------AVTGWYKLFPTSSVADSTLGS 289
V W++L +V T GS
Sbjct: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGS 580
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 48.9 bits (115), Expect = 6e-06
Identities = 41/155 (26%), Positives = 70/155 (45%), Gaps = 28/155 (18%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPAT-----YIKVYLLENGACLAKK 209
+G+++ ++ + +G+L V +I+A L K++ T Y+K L+ G L K+
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNL------KAMDLTGFSDPYVKASLISEGRRLKKR 485
Query: 210 KTKMTKKTCDPLYQQALLFDEGPQG--KVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLS 267
KT + K T +P Y +AL+FD P+ V I DY + H +G+ ++ D D
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
Query: 268 A-------------AVTGWYKLFPTSSVADSTLGS 289
V W++L +V T GS
Sbjct: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGS 580
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 48.9 bits (115), Expect = 6e-06
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Query: 162 IAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPL 221
+ + +G++ + VI+ R L + S Y+KV L+ G L K+KT K T +P+
Sbjct: 371 LCYLPTAGRMTLTVIKCRNLKAMDITGSSDP-YVKVSLMCEGRRLKKRKTTTKKNTLNPV 429
Query: 222 YQQALLFDEGPQG--KVLQVIVWGDYGRMDHKCFMGMAQIMLD 262
Y +A++FD P+ +V I DY R+ H +G+ + LD
Sbjct: 430 YNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD 472
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 48.5 bits (114), Expect = 7e-06
Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 171 LEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDE 230
L V V E L +K Y+K YLL + + K+KT + + T +PLY + L + E
Sbjct: 373 LVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY-E 431
Query: 231 GPQG----KVLQVIVWGDYGRMDHKCFMGMAQIMLDELDL 266
P+ + LQ VW +GR F+G A+I +D L
Sbjct: 432 IPESLLAQRTLQFSVW-HHGRFGRNTFLGEAEIQMDSWKL 470
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
Query: 154 TPPMGDVHIAIMDRSGQLEVEVIEARGLTP-KPGSKSLPATYIKVYLLENGACLAKKKTK 212
TP GD + G+L+V + EA+ LT K G S +++K YLL +K+KT
Sbjct: 511 TPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTS--DSFVKGYLLPMRNKASKRKTP 568
Query: 213 MTKKTCDPLYQQALLFD----EGPQGKVLQVIVW 242
+ KKT +P Y +++ E Q L++ VW
Sbjct: 569 VMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVW 602
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 48.5 bits (114), Expect = 7e-06
Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 171 LEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDE 230
L V V E L +K Y+K YLL + + K+KT + + T +PLY + L + E
Sbjct: 373 LVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY-E 431
Query: 231 GPQG----KVLQVIVWGDYGRMDHKCFMGMAQIMLDELDL 266
P+ + LQ VW +GR F+G A+I +D L
Sbjct: 432 IPESLLAQRTLQFSVW-HHGRFGRNTFLGEAEIQMDSWKL 470
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
Query: 154 TPPMGDVHIAIMDRSGQLEVEVIEARGLTP-KPGSKSLPATYIKVYLLENGACLAKKKTK 212
TP GD + G+L+V + EA+ LT K G S +++K YLL +K+KT
Sbjct: 511 TPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTS--DSFVKGYLLPMRNKASKRKTP 568
Query: 213 MTKKTCDPLYQQALLFD----EGPQGKVLQVIVW 242
+ KKT +P Y +++ E Q L++ VW
Sbjct: 569 VMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVW 602
>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
Length = 542
Score = 48.5 bits (114), Expect = 7e-06
Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 6/132 (4%)
Query: 158 GDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK 215
G++ AI ++ LE+ + + L K Y+K YLL + + K+KT + +
Sbjct: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
Query: 216 KTCDPLYQQALLFDEGPQGKV---LQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTG 272
T DP +Q+ L + P V LQV VW G + + F+G I L D + T
Sbjct: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVW-HLGTLARRVFLGEVIIPLATWDFEDSTTQ 358
Query: 273 WYKLFPTSSVAD 284
++ P + A+
Sbjct: 359 SFRWHPLRAKAE 370
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/75 (33%), Positives = 45/75 (60%), Gaps = 3/75 (4%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMT 214
+GD+ ++ + +G+L V ++EA+ L K L Y+K++L++NG L KKKT +
Sbjct: 274 LGDICFSLRYVPTAGKLTVVILEAKNLK-KMDVGGLSDPYVKIHLMQNGKRLKKKKTTIK 332
Query: 215 KKTCDPLYQQALLFD 229
K T +P Y ++ F+
Sbjct: 333 KNTLNPYYNESFSFE 347
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/75 (33%), Positives = 45/75 (60%), Gaps = 3/75 (4%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMT 214
+GD+ ++ + +G+L V ++EA+ L K L Y+K++L++NG L KKKT +
Sbjct: 274 LGDICFSLRYVPTAGKLTVVILEAKNLK-KMDVGGLSDPYVKIHLMQNGKRLKKKKTTIK 332
Query: 215 KKTCDPLYQQALLFD 229
K T +P Y ++ F+
Sbjct: 333 KNTLNPYYNESFSFE 347
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/75 (33%), Positives = 45/75 (60%), Gaps = 3/75 (4%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMT 214
+GD+ ++ + +G+L V ++EA+ L K L Y+K++L++NG L KKKT +
Sbjct: 274 LGDICFSLRYVPTAGKLTVVILEAKNLK-KMDVGGLSDPYVKIHLMQNGKRLKKKKTTIK 332
Query: 215 KKTCDPLYQQALLFD 229
K T +P Y ++ F+
Sbjct: 333 KNTLNPYYNESFSFE 347
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 47.4 bits (111), Expect = 2e-05
Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 6/118 (5%)
Query: 171 LEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDE 230
L V++++A+ L K S + ++K+YLL + K +TK+ +K +P + + LF+
Sbjct: 152 LTVKIMKAQELPAKDFSGTSDP-FVKIYLLPDKK--HKLETKVKRKNLNPHWNETFLFEG 208
Query: 231 GPQGKVLQVIVW---GDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADS 285
P KV+Q I++ DY R +G I L+++DL+ T W L P S + S
Sbjct: 209 FPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGS 266
Score = 34.3 bits (77), Expect = 0.14
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 173 VEVIEARGLTPKP-GSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFD 229
V +I+AR L G S P Y+KV+L+ + KKKT K+ +P++ ++ FD
Sbjct: 285 VNIIKARNLKAMDIGGTSDP--YVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFD 340
>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
Length = 752
Score = 46.6 bits (109), Expect = 3e-05
Identities = 73/306 (23%), Positives = 117/306 (38%), Gaps = 43/306 (14%)
Query: 6 PGPASSGASRNVVRSSSISGEIC--GSQQAGGGAGTT---TAKKRRSSLGAKMVAIVGLT 60
PG SS A +S IS E S GT+ T RR++ G +A+ G +
Sbjct: 258 PGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRRNTSGTPSIAVSGTS 317
Query: 61 ---QWSKSTLQLPQPEGATKKLRSNIR-------------RSTETGIAVEMRSRVTRQGS 104
S+S L L + + +IR TE I + S+++
Sbjct: 318 LSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTH 377
Query: 105 RESTDGSTNSNS-SDGTFIF--------PTTRLGAESQFSDFLDGLGPAQIVGRQTLATP 155
R ++ ST+S + SD + + TT L + G ++ G L
Sbjct: 378 RLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILL--- 434
Query: 156 PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK 215
HI+ ++G L + V R L K Y+K YLL + + K+KTK+
Sbjct: 435 -----HISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
Query: 216 KTCDPLYQQALLFDEGP---QGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTG 272
T +P + + L + + + LQ+ VW Y R F+G +I D +
Sbjct: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVW-HYDRFGRNSFLGEVEIPFDSWNFENPTDE 547
Query: 273 WYKLFP 278
W+ L P
Sbjct: 548 WFVLQP 553
Score = 35.8 bits (81), Expect = 0.049
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 141 LGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTP-KPGSKSLPATYIKVYL 199
L P Q+ G +T G + + G LEV + EA+ LT K G S +++K YL
Sbjct: 584 LPPEQLQGNKTFKK---GKKKESPVISGGILEVFIKEAKNLTAVKSGGTS--DSFVKGYL 638
Query: 200 LENGACLAKKKTKMTKKTCDPLYQQALLFD----EGPQGKVLQVIVWGDYGRMDHKCFMG 255
L + + K KT + KK+ +P + +F + + L++ +W D F+G
Sbjct: 639 LPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIW-DKEAFSSNIFLG 697
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 46.6 bits (109), Expect = 3e-05
Identities = 25/75 (33%), Positives = 46/75 (61%), Gaps = 3/75 (4%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMT 214
+GD+ ++ + +G+L V ++EA+ L K L Y+K++L++NG L KKKT +
Sbjct: 271 LGDICTSLRYVPTAGKLTVCILEAKNLK-KMDVGGLSDPYVKIHLMQNGKRLKKKKTTVK 329
Query: 215 KKTCDPLYQQALLFD 229
KKT +P + ++ F+
Sbjct: 330 KKTLNPYFNESFSFE 344
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 46.6 bits (109), Expect = 3e-05
Identities = 25/75 (33%), Positives = 46/75 (61%), Gaps = 3/75 (4%)
Query: 157 MGDVHIAI--MDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMT 214
+GD+ ++ + +G+L V ++EA+ L K L Y+K++L++NG L KKKT +
Sbjct: 271 LGDICTSLRYVPTAGKLTVCILEAKNLK-KMDVGGLSDPYVKIHLMQNGKRLKKKKTTVK 329
Query: 215 KKTCDPLYQQALLFD 229
KKT +P + ++ F+
Sbjct: 330 KKTLNPYFNESFSFE 344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,554,324
Number of Sequences: 37866
Number of extensions: 499274
Number of successful extensions: 1475
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 1353
Number of HSP's gapped (non-prelim): 165
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.