Search of human proteins with 13376097

Search of human proteins with 13376097

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13376097 NIPA-like domain containing 2 [Homo sapiens]
         (368 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13376097 NIPA-like domain containing 2 [Homo sapiens]              729   0.0  
gi|10092687 NIPA-like domain containing 3 [Homo sapiens]              310   2e-84
gi|46409302 NIPA-like domain containing 1 [Homo sapiens]              154   2e-37
gi|149944536 ichthyin protein [Homo sapiens]                          150   2e-36
gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 is...   149   3e-36
gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 is...   149   3e-36
gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 is...   149   3e-36
gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 is...   130   2e-30
gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 is...   102   4e-22
gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 i...    86   7e-17
gi|109689695 transient receptor potential cation channel, subfam...    32   0.91 
gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Hom...    32   1.2  
gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]        31   1.5  
gi|21687270 MARVEL domain containing 2 isoform beta [Homo sapiens]     31   1.5  
gi|7706529 CD244 natural killer cell receptor 2B4 [Homo sapiens]       31   2.0  
gi|13376856 solute carrier family 19, member 3 [Homo sapiens]          31   2.0  
gi|4557461 nicotinic acetylcholine receptor delta polypeptide pr...    30   2.6  
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]        30   2.6  
gi|211063479 major facilitator superfamily domain containing 2 i...    30   3.4  
gi|42713696 major facilitator superfamily domain containing 2 is...    30   3.4  
gi|170650643 solute carrier family 22, member 23 isoform a [Homo...    30   4.5  
gi|119220552 sidekick 1 [Homo sapiens]                                 29   5.9  
gi|224465231 solute carrier family 9, member 11 [Homo sapiens]         29   5.9  

>gi|13376097 NIPA-like domain containing 2 [Homo sapiens]
          Length = 368

 Score =  729 bits (1882), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MAAVAPAGPGDSASAALDELSLNFTYGAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLV 60
           MAAVAPAGPGDSASAALDELSLNFTYGAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLV
Sbjct: 1   MAAVAPAGPGDSASAALDELSLNFTYGAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLV 60

Query: 61  ISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLG 120
           ISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLG
Sbjct: 61  ISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLG 120

Query: 121 CVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGW 180
           CVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGW
Sbjct: 121 CVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGW 180

Query: 181 QFLIYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDK 240
           QFLIYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDK
Sbjct: 181 QFLIYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDK 240

Query: 241 MQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQE 300
           MQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQE
Sbjct: 241 MQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQE 300

Query: 301 FLGAPFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIPDTTPERKAWRETNV 360
           FLGAPFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIPDTTPERKAWRETNV
Sbjct: 301 FLGAPFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIPDTTPERKAWRETNV 360

Query: 361 GQNTTRFT 368
           GQNTTRFT
Sbjct: 361 GQNTTRFT 368


>gi|10092687 NIPA-like domain containing 3 [Homo sapiens]
          Length = 406

 Score =  310 bits (793), Expect = 2e-84
 Identities = 158/343 (46%), Positives = 225/343 (65%), Gaps = 14/343 (4%)

Query: 12  SASAALDELSLNFTYGAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLVISISLNIQKYS 71
           S SAAL    L  T  +      S S   Y+ N   L G LLAI G+LV+SI+LN+QKY 
Sbjct: 4   SHSAALKLQQLPPTSSSSAVSEASFS---YKEN---LIGALLAIFGHLVVSIALNLQKYC 57

Query: 72  HLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIIS 131
           H++LA  + PR YFK+  WW G+ LM +GE G FA+Y FAP++LI PL  VSV  SAII 
Sbjct: 58  HIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIG 117

Query: 132 VTFLKDNLRASDLL--------GTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFL 183
           + F+K+  +  D L        G  LA  GTYLLV FAPN  + ++   V  +LV W FL
Sbjct: 118 IIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFL 177

Query: 184 IYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQL 243
           +Y+++EI++FC+LLYFYK K   ++V++L LVA+L S+TV++VKAV+GM+  S+   +QL
Sbjct: 178 LYMLVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQL 237

Query: 244 TYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLG 303
            YPIFY+MF+ M+A+ V+Q  FL+QA+++Y+++ +  V +I  T  AI AG IFY +F+G
Sbjct: 238 DYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIG 297

Query: 304 APFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIP 346
              L + ++  GC ++FLGVFL+TRNR+K    + YI    +P
Sbjct: 298 EDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMP 340


>gi|46409302 NIPA-like domain containing 1 [Homo sapiens]
          Length = 410

 Score =  154 bits (388), Expect = 2e-37
 Identities = 89/301 (29%), Positives = 162/301 (53%), Gaps = 8/301 (2%)

Query: 33  NGSLSGDWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLQLAQQEHPRP------YFK 86
           N S+S +   +  +++ G++LA+  ++ I  S  ++K   LQLA +   R       Y K
Sbjct: 55  NLSISANVENKYSLYV-GLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLK 113

Query: 87  SVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLG 146
             LWW G+L M  GE  NFAAY FAP TL+ PLG +SV  SAI+S  FL ++L     +G
Sbjct: 114 EWLWWVGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIG 173

Query: 147 TTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFLIY-VILEILIFCILLYFYKRKGM 205
             L+  G+ ++V  AP   +  S   ++  L    F+ + VI+ ++   ++L    +KG 
Sbjct: 174 CILSILGSTVMVIHAPQEEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQ 233

Query: 206 KHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKF 265
            ++++ +++ +++ + +V SVK +   I   +  K    +P+ +++  +++ S   Q+ +
Sbjct: 234 TNILVYISICSLIGAFSVSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINY 293

Query: 266 LNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFL 325
           LN+A   +NT+ V P+ ++FFT   +    I +QE+ G     +   L G F   +G+FL
Sbjct: 294 LNKALDTFNTSLVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFL 353

Query: 326 V 326
           +
Sbjct: 354 L 354


>gi|149944536 ichthyin protein [Homo sapiens]
          Length = 466

 Score =  150 bits (378), Expect = 2e-36
 Identities = 89/293 (30%), Positives = 156/293 (53%), Gaps = 9/293 (3%)

Query: 42  RRNQIHLFGVLLAILGNLVISISLNIQKYSHLQLAQQEHPRP------YFKSVLWWGGVL 95
           R+N     G+ LA L + +I  S+ ++K   L+L      R       Y K  +WW G L
Sbjct: 113 RQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFL 172

Query: 96  LMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTY 155
            MA GE  NF AY FAP T++ PLG +SV  SAI+S  FL+++L     LG  +  AG+ 
Sbjct: 173 TMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGST 232

Query: 156 LLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFY--KRKGMKHMVILLT 213
           ++V  AP   +  +   +   +    F+++ +L +L+ C++L F    R G ++++I + 
Sbjct: 233 VMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVL-LLVSCLILIFVIAPRYGQRNILIYII 291

Query: 214 LVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLY 273
           + +++ + +V +VK +   I         + +P+ YI+ +I+  S   QV FLN+A  ++
Sbjct: 292 ICSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIF 351

Query: 274 NTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLV 326
           NT+ V P+ ++FFT   + + II ++E+     + +   L G     LGVF++
Sbjct: 352 NTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFML 404


>gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score =  149 bits (377), Expect = 3e-36
 Identities = 87/284 (30%), Positives = 152/284 (53%), Gaps = 7/284 (2%)

Query: 50  GVLLAILGNLVISISLNIQKYSHLQLAQQEHPRP------YFKSVLWWGGVLLMAVGETG 103
           G+ LA+  ++ I  S  ++K   L+LA++   R       Y K  LWW G+L M  GE  
Sbjct: 13  GLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72

Query: 104 NFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPN 163
           NFAAY FAP TL+ PLG +SV  SAI+S  FL + L     +G  L+  G+ ++V  AP 
Sbjct: 73  NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132

Query: 164 ITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFY-KRKGMKHMVILLTLVAILASLT 222
             +  +   + + L    F+++  L +++  IL++    R G  ++++ +T+ +++ + +
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFS 192

Query: 223 VISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVN 282
           V  VK +   I      K  L +P+ +I+ + +I     Q+ +LN+A  ++NT+ V P+ 
Sbjct: 193 VSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252

Query: 283 HIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLV 326
           ++FFT S +    I ++E+   P   V   L G F   +G+FL+
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL 296


>gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score =  149 bits (377), Expect = 3e-36
 Identities = 87/284 (30%), Positives = 152/284 (53%), Gaps = 7/284 (2%)

Query: 50  GVLLAILGNLVISISLNIQKYSHLQLAQQEHPRP------YFKSVLWWGGVLLMAVGETG 103
           G+ LA+  ++ I  S  ++K   L+LA++   R       Y K  LWW G+L M  GE  
Sbjct: 13  GLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72

Query: 104 NFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPN 163
           NFAAY FAP TL+ PLG +SV  SAI+S  FL + L     +G  L+  G+ ++V  AP 
Sbjct: 73  NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132

Query: 164 ITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFY-KRKGMKHMVILLTLVAILASLT 222
             +  +   + + L    F+++  L +++  IL++    R G  ++++ +T+ +++ + +
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFS 192

Query: 223 VISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVN 282
           V  VK +   I      K  L +P+ +I+ + +I     Q+ +LN+A  ++NT+ V P+ 
Sbjct: 193 VSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252

Query: 283 HIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLV 326
           ++FFT S +    I ++E+   P   V   L G F   +G+FL+
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL 296


>gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score =  149 bits (377), Expect = 3e-36
 Identities = 87/284 (30%), Positives = 152/284 (53%), Gaps = 7/284 (2%)

Query: 50  GVLLAILGNLVISISLNIQKYSHLQLAQQEHPRP------YFKSVLWWGGVLLMAVGETG 103
           G+ LA+  ++ I  S  ++K   L+LA++   R       Y K  LWW G+L M  GE  
Sbjct: 13  GLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72

Query: 104 NFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPN 163
           NFAAY FAP TL+ PLG +SV  SAI+S  FL + L     +G  L+  G+ ++V  AP 
Sbjct: 73  NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132

Query: 164 ITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFY-KRKGMKHMVILLTLVAILASLT 222
             +  +   + + L    F+++  L +++  IL++    R G  ++++ +T+ +++ + +
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFS 192

Query: 223 VISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVN 282
           V  VK +   I      K  L +P+ +I+ + +I     Q+ +LN+A  ++NT+ V P+ 
Sbjct: 193 VSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252

Query: 283 HIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLV 326
           ++FFT S +    I ++E+   P   V   L G F   +G+FL+
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL 296


>gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform b [Homo sapiens]
          Length = 341

 Score =  130 bits (327), Expect = 2e-30
 Identities = 79/278 (28%), Positives = 145/278 (52%), Gaps = 14/278 (5%)

Query: 50  GVLLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYG 109
           G+ LA+  ++ I  S  ++K   L+LA++             G +  +  GE  NFAAY 
Sbjct: 13  GLGLAMSSSIFIGGSFILKKKGLLRLARK-------------GSMRAVGAGEVANFAAYA 59

Query: 110 FAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAIS 169
           FAP TL+ PLG +SV  SAI+S  FL + L     +G  L+  G+ ++V  AP   +  +
Sbjct: 60  FAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIET 119

Query: 170 ARTVQYYLVGWQFLIYVILEILIFCILLYFY-KRKGMKHMVILLTLVAILASLTVISVKA 228
              + + L    F+++  L +++  IL++    R G  ++++ +T+ +++ + +V  VK 
Sbjct: 120 LNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKG 179

Query: 229 VSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTI 288
           +   I      K  L +P+ +I+ + +I     Q+ +LN+A  ++NT+ V P+ ++FFT 
Sbjct: 180 LGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTT 239

Query: 289 SAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLV 326
           S +    I ++E+   P   V   L G F   +G+FL+
Sbjct: 240 SVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL 277


>gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1
           isoform 1 [Homo sapiens]
          Length = 329

 Score =  102 bits (255), Expect = 4e-22
 Identities = 59/256 (23%), Positives = 133/256 (51%), Gaps = 7/256 (2%)

Query: 50  GVLLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYG 109
           G+ +A++ +LV   +  +QK   ++  ++     Y   ++WW G + MAVG+ GNF AY 
Sbjct: 31  GLGVAVVSSLVNGSTFVLQKKGIVRAKRRG--TSYLTDIVWWAGTIAMAVGQIGNFLAYT 88

Query: 110 FAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAIS 169
             P  L+ PLG + V   +I++   LK+ L     LG  L+ AG+ +L+  +P      +
Sbjct: 89  AVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLIIHSPKSESVTT 148

Query: 170 ARTVQYYLVGWQFLIYVILEILIFCILLYFY-KRKGMKHMVILLTLVAILASLTVISVKA 228
              ++  L    F+ Y+ + +L+  +L+++     G  ++++ +++ ++L S TV S K 
Sbjct: 149 QAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTVPSTKG 208

Query: 229 VSGMITFSVM---DKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIF 285
           + G+    ++      Q    +  ++  ++  S + Q +++N+A + ++++    + ++ 
Sbjct: 209 I-GLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAIYYVV 267

Query: 286 FTISAIIAGIIFYQEF 301
           FT   ++A  I ++E+
Sbjct: 268 FTTLVLLASAILFREW 283


>gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1
           isoform 2 [Homo sapiens]
          Length = 254

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 49/209 (23%), Positives = 109/209 (52%), Gaps = 5/209 (2%)

Query: 97  MAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYL 156
           MAVG+ GNF AY   P  L+ PLG + V   +I++   LK+ L     LG  L+ AG+ +
Sbjct: 1   MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60

Query: 157 LVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFY-KRKGMKHMVILLTLV 215
           L+  +P      +   ++  L    F+ Y+ + +L+  +L+++     G  ++++ +++ 
Sbjct: 61  LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120

Query: 216 AILASLTVISVKAVSGMITFSVM---DKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKL 272
           ++L S TV S K + G+    ++      Q    +  ++  ++  S + Q +++N+A + 
Sbjct: 121 SLLGSFTVPSTKGI-GLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALEC 179

Query: 273 YNTTTVVPVNHIFFTISAIIAGIIFYQEF 301
           ++++    + ++ FT   ++A  I ++E+
Sbjct: 180 FDSSVFGAIYYVVFTTLVLLASAILFREW 208


>gi|109689695 transient receptor potential cation channel, subfamily
           M, member 8 [Homo sapiens]
          Length = 1104

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 37/161 (22%), Positives = 70/161 (43%), Gaps = 18/161 (11%)

Query: 172 TVQYYLVGWQFLIYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSG 231
           T  + +  W  + Y+   +L   +LL  +        ++L +LV +L     +    V+G
Sbjct: 732 TSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHPPELVLYSLVFVL-FCDEVRQWYVNG 790

Query: 232 MITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAI 291
           +  F+ +  +  T  +FY      IA  VF++   N+++ LY+   +  +++I FT+  I
Sbjct: 791 VNYFTDLWNVMDTLGLFY-----FIAGIVFRLHSSNKSS-LYSGRVIFCLDYIIFTLRLI 844

Query: 292 I---------AGIIFYQEFLGAPFLTVFIYLFGCFLSFLGV 323
                       II  Q  L   F   F++LF  ++   GV
Sbjct: 845 HIFTVSRNLGPKIIMLQRMLIDVFF--FLFLFAVWMVAFGV 883


>gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo
           sapiens]
          Length = 358

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 35/205 (17%)

Query: 83  PYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRAS 142
           P   SV++  GVL       GN  A           +GC +   S++     L   L  +
Sbjct: 25  PAISSVMFSAGVL-------GNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFT 77

Query: 143 DLLGTTLAFAGTYLLVNFAPN---ITQAISARTVQYYLVGWQFLIYVILEILIFCILL-- 197
           DLLGT L      +L ++A N   +  A  +R   Y+     F     + +++F + L  
Sbjct: 78  DLLGTCL--ISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATM-LMLFAMALER 134

Query: 198 -------YFYKRK-----GMKHMVILLTLVAILASLTVIS----VKAVSGMITFSVMDK- 240
                  YFY+R+     G+  + ++  +  +  SL ++     V+   G   F    + 
Sbjct: 135 YLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRT 194

Query: 241 --MQLTYPIFYIMFIIMIASCVFQV 263
             +QL Y    ++ I+ + +C F V
Sbjct: 195 AYLQL-YATLLLLLIVSVLACNFSV 218


>gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]
          Length = 558

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 11/104 (10%)

Query: 251 MFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTI-SAIIAGIIFYQEFLGAPFLTV 309
           +FI+ +A+ +  V   N+    Y      PVN +F  +    IA +IF        F+T+
Sbjct: 300 LFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFL-------FVTM 352

Query: 310 FIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIPDTTPERK 353
            +YL    +           R +E+++Q  I   N P  + +RK
Sbjct: 353 IVYLISALVCLKLWRHEAARRHREYMEQQEI---NEPSLSSKRK 393


>gi|21687270 MARVEL domain containing 2 isoform beta [Homo sapiens]
          Length = 457

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 11/104 (10%)

Query: 251 MFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTI-SAIIAGIIFYQEFLGAPFLTV 309
           +FI+ +A+ +  V   N+    Y      PVN +F  +    IA +IF        F+T+
Sbjct: 300 LFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFL-------FVTM 352

Query: 310 FIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIPDTTPERK 353
            +YL    +           R +E+++Q  I   N P  + +RK
Sbjct: 353 IVYLISALVCLKLWRHEAARRHREYMEQQEI---NEPSLSSKRK 393


>gi|7706529 CD244 natural killer cell receptor 2B4 [Homo sapiens]
          Length = 365

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 15/36 (41%), Positives = 19/36 (52%)

Query: 298 YQEFLGAPFLTVFIYLFGCFLSFLGVFLVTRNREKE 333
           +QEF   PFL + + L   FL  L  F V R + KE
Sbjct: 217 HQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKE 252


>gi|13376856 solute carrier family 19, member 3 [Homo sapiens]
          Length = 496

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 41/198 (20%), Positives = 77/198 (38%), Gaps = 30/198 (15%)

Query: 156 LLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYKRKGMKHMV------ 209
           + V +  ++ +  S++ + Y+ + W F      ++L +  +L+ YK       +      
Sbjct: 261 VFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVE 320

Query: 210 ILLTLVAILASLTVISVK------AVSGMITFSVMDKMQL--------------TYPIFY 249
            + T    +A+  V  VK          ++ FSV++   L               Y IF 
Sbjct: 321 AIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFK 380

Query: 250 IMFIIMIASCVFQVKFLNQATKLYNTTTVVPVN-HIFFTISAIIAGIIFYQEFLGAPFLT 308
             ++++I   VFQ+  +N   + Y    V  +N  I   I  I+  I+  Q  L  P   
Sbjct: 381 SSYMLLITIAVFQIA-VNLNVERY--ALVFGINTFIALVIQTIMTVIVVDQRGLNLPVSI 437

Query: 309 VFIYLFGCFLSFLGVFLV 326
            F+     F    G+FL+
Sbjct: 438 QFLVYGSYFAVIAGIFLM 455


>gi|4557461 nicotinic acetylcholine receptor delta polypeptide
           precursor [Homo sapiens]
          Length = 517

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 23/110 (20%), Positives = 50/110 (45%), Gaps = 9/110 (8%)

Query: 169 SARTVQYYLVGWQFLIYVILEILIFCILL--------YFYKRKGMKHMVILLTLVAILAS 220
           S + + +YL+  +  ++ I+ IL+ C+L+        Y     G K  V +  L+A    
Sbjct: 232 SRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPADSGEKTSVAISVLLAQSVF 291

Query: 221 LTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQAT 270
           L +IS +  +  +   ++ K  L + +  +  +++I   V  + F   +T
Sbjct: 292 LLLISKRLPATSMAIPLIGKF-LLFGMVLVTMVVVICVIVLNIHFRTPST 340


>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
          Length = 5183

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 5/52 (9%)

Query: 6    PAGPGDSASAALDELSLNFTY----GAPGAGNGSLSGDWYRRNQIHLFGVLL 53
            PAGPG S S++   +S    +    G+ G G G   GD +  N++H+  ++L
Sbjct: 2927 PAGPG-SVSSSTGAISTTTGHQEGDGSEGEGEGETEGDVHTSNRLHMVRLML 2977


>gi|211063479 major facilitator superfamily domain containing 2
           isoform 1 [Homo sapiens]
          Length = 543

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 49/219 (22%), Positives = 89/219 (40%), Gaps = 31/219 (14%)

Query: 50  GVLLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYG 109
           GV++ I     + + L +++      AQQ  P  YF+ +      L+M+ G        G
Sbjct: 260 GVIVCIYIICAVILILGVREQREPYEAQQSEPIAYFRGLR-----LVMSHGPYIKLIT-G 313

Query: 110 FAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAIS 169
           F    L   L  + V G+ ++  T+             TL F   +  +  A  ++  ++
Sbjct: 314 F----LFTSLAFMLVEGNFVLFCTY-------------TLGFRNEFQNLLLAIMLSATLT 356

Query: 170 ARTVQYYLV--GWQFLIYV-ILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISV 226
               Q++L   G +  +YV I   + F IL+       M+  +I+   VA+ A ++V + 
Sbjct: 357 IPIWQWFLTRFGKKTAVYVGISSAVPFLILVAL-----MESNLIITYAVAVAAGISVAAA 411

Query: 227 KAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKF 265
             +   +   V+D   L  P F+    I  +  VF  KF
Sbjct: 412 FLLPWSMLPDVIDDFHLKQPHFHGTEPIFFSFYVFFTKF 450


>gi|42713696 major facilitator superfamily domain containing 2
           isoform 2 [Homo sapiens]
          Length = 530

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 49/219 (22%), Positives = 89/219 (40%), Gaps = 31/219 (14%)

Query: 50  GVLLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYG 109
           GV++ I     + + L +++      AQQ  P  YF+ +      L+M+ G        G
Sbjct: 247 GVIVCIYIICAVILILGVREQREPYEAQQSEPIAYFRGLR-----LVMSHGPYIKLIT-G 300

Query: 110 FAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAIS 169
           F    L   L  + V G+ ++  T+             TL F   +  +  A  ++  ++
Sbjct: 301 F----LFTSLAFMLVEGNFVLFCTY-------------TLGFRNEFQNLLLAIMLSATLT 343

Query: 170 ARTVQYYLV--GWQFLIYV-ILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISV 226
               Q++L   G +  +YV I   + F IL+       M+  +I+   VA+ A ++V + 
Sbjct: 344 IPIWQWFLTRFGKKTAVYVGISSAVPFLILVAL-----MESNLIITYAVAVAAGISVAAA 398

Query: 227 KAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKF 265
             +   +   V+D   L  P F+    I  +  VF  KF
Sbjct: 399 FLLPWSMLPDVIDDFHLKQPHFHGTEPIFFSFYVFFTKF 437


>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
           sapiens]
          Length = 686

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 10/36 (27%), Positives = 22/36 (61%)

Query: 39  DWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLQ 74
           DW  R  + LF ++  ++  L +++S+N+  +S L+
Sbjct: 252 DWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLR 287


>gi|119220552 sidekick 1 [Homo sapiens]
          Length = 2213

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 13/34 (38%), Positives = 18/34 (52%)

Query: 5    APAGPGDSASAALDELSLNFTYGAPGAGNGSLSG 38
            AP  P   A + +   +LN ++G P A NG L G
Sbjct: 1801 APGAPSFLAFSEITSTTLNVSWGEPAAANGILQG 1834


>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
          Length = 1124

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 148 TLAFAGTYLLVN---FAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYKRKG 204
           TLA A   L ++   F P I   I+ + ++ +   ++ LIY    I+I C  L  Y+   
Sbjct: 276 TLALAAVGLNLDSLTFKPKIELVIT-KFLRIFSSVYEHLIYAFFGIVIGCGELSHYEFHT 334

Query: 205 MKHMVILLTLVAILASLTVISVKAV 229
           +  + IL T V ++  LT++ V  +
Sbjct: 335 IPFIFILFTTVNLVRLLTILLVSPI 359


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,222,819
Number of Sequences: 37866
Number of extensions: 484281
Number of successful extensions: 1895
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1869
Number of HSP's gapped (non-prelim): 26
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.