Guide to the Human Genome
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Search of human proteins with 13375985

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13375985 zinc finger, AN1-type domain 1 [Homo sapiens]
         (268 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13375985 zinc finger, AN1-type domain 1 [Homo sapiens]             566   e-162
gi|20270357 zinc finger, AN1-type domain 2B [Homo sapiens]             78   7e-15
gi|226532848 zinc finger, AN1-type domain 2A [Homo sapiens]            77   2e-14
gi|61676193 zinc finger protein 260 [Homo sapiens]                     34   0.15 
gi|15559211 RE1-silencing transcription factor [Homo sapiens]          33   0.20 
gi|109150431 ring finger protein 31 [Homo sapiens]                     33   0.26 
gi|11345484 zinc finger, AN1-type domain 3 [Homo sapiens]              33   0.34 
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ...    31   1.3  
gi|13430850 RB-associated KRAB repressor [Homo sapiens]                31   1.3  
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom...    31   1.3  
gi|90652851 zinc finger transcription factor TRPS1 [Homo sapiens]      30   2.2  
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]        28   6.4  
gi|110815807 zinc finger protein 169 [Homo sapiens]                    28   6.4  
gi|194097339 zinc finger protein 222 isoform 1 [Homo sapiens]          28   8.4  
gi|194018453 zinc finger protein 222 isoform 2 [Homo sapiens]          28   8.4  
gi|33354279 hypothetical protein LOC55425 [Homo sapiens]               28   8.4  

>gi|13375985 zinc finger, AN1-type domain 1 [Homo sapiens]
          Length = 268

 Score =  566 bits (1458), Expect = e-162
 Identities = 268/268 (100%), Positives = 268/268 (100%)

Query: 1   MAELDIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHT 60
           MAELDIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHT
Sbjct: 1   MAELDIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHT 60

Query: 61  SYPCSFKDCAERELVAVICPYCEKNFCLRHRHQSDHECEKLEIPKPRMAATQKLVKDIID 120
           SYPCSFKDCAERELVAVICPYCEKNFCLRHRHQSDHECEKLEIPKPRMAATQKLVKDIID
Sbjct: 61  SYPCSFKDCAERELVAVICPYCEKNFCLRHRHQSDHECEKLEIPKPRMAATQKLVKDIID 120

Query: 121 SKTGETASKRWKGAKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKEKSKP 180
           SKTGETASKRWKGAKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKEKSKP
Sbjct: 121 SKTGETASKRWKGAKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKEKSKP 180

Query: 181 MLFCHRWSIGKAIDFAASLARLKNDNNKFTAKKLRLCHITSGEALPLDHTLETWIAKEDC 240
           MLFCHRWSIGKAIDFAASLARLKNDNNKFTAKKLRLCHITSGEALPLDHTLETWIAKEDC
Sbjct: 181 MLFCHRWSIGKAIDFAASLARLKNDNNKFTAKKLRLCHITSGEALPLDHTLETWIAKEDC 240

Query: 241 PLYNGGNIILEYLNDEEQFCKNVESYLE 268
           PLYNGGNIILEYLNDEEQFCKNVESYLE
Sbjct: 241 PLYNGGNIILEYLNDEEQFCKNVESYLE 268


>gi|20270357 zinc finger, AN1-type domain 2B [Homo sapiens]
          Length = 257

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 36/130 (27%)

Query: 5   DIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGC-------------------- 44
           D+G HC    C++ DFLP  CD CSGIFC +H +   H C                    
Sbjct: 5   DLGAHCSEPSCQRLDFLPLKCDACSGIFCADHVAYAQHHCGSAYQKDIQVPVCPLCNVPV 64

Query: 45  ------PEVTVINERLKTDQHT----------SYPCSFKDCAERELVAVICPYCEKNFCL 88
                 P    + E +  D  +          +  C    C +RE++ + C  C +NFC+
Sbjct: 65  PVARGEPPDRAVGEHIDRDCRSDPAQQKRKIFTNKCERAGCRQREMMKLTCERCSRNFCI 124

Query: 89  RHRHQSDHEC 98
           +HRH  DH+C
Sbjct: 125 KHRHPLDHDC 134


>gi|226532848 zinc finger, AN1-type domain 2A [Homo sapiens]
          Length = 145

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 36/130 (27%)

Query: 5   DIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEV----------------- 47
           D+G+HC  + C+Q DFLP  CD C   FC +H    +H CP                   
Sbjct: 5   DLGKHCSEKTCKQLDFLPVKCDACKQDFCKDHFPYAAHKCPFAFQKDVHVPVCPLCNTPI 64

Query: 48  ---------TVINERL----------KTDQHTSYPCSFKDCAERELVAVICPYCEKNFCL 88
                     V+ + +          K ++  +Y CS + C ++E++ ++C  C  NFC+
Sbjct: 65  PVKKGQIPDVVVGDHIDRDCDSHPGKKKEKIFTYRCSKEGCKKKEMLQMVCAQCHGNFCI 124

Query: 89  RHRHQSDHEC 98
           +HRH  DH C
Sbjct: 125 QHRHPLDHSC 134


>gi|61676193 zinc finger protein 260 [Homo sapiens]
          Length = 412

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 33/131 (25%)

Query: 3   ELDIGQHCQVEHCRQRDFLPFVCDDCSGIFCLE---------HRSRESHGCPEVTVINER 53
           E D+ QH Q+ H  ++   P+ C++C   F L+         H   +SH C E   +  R
Sbjct: 11  ESDLLQHDQI-HTGEK---PYECNECRKTFSLKQNLVEHKKMHTGEKSHECTECGKVCSR 66

Query: 54  LKT-----DQHT---SYPCSFKDCAERELVAVICPYCEKNFCLRHRH---QSDHECEKLE 102
           + +       HT   +Y C+    A  +         ++NF    +H   +  +ECEK+ 
Sbjct: 67  VSSLTLHLRSHTGKKAYKCNKCGKAFSQ---------KENFLSHQKHHTGEKPYECEKVS 117

Query: 103 IPKPRMAATQK 113
           I  P +   QK
Sbjct: 118 IQMPTIIRHQK 128


>gi|15559211 RE1-silencing transcription factor [Homo sapiens]
          Length = 1097

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 16/117 (13%)

Query: 22  PFVCDDCSGIFCLEH----RSRESHGCPEVTVINERLKTDQHTSYPCSFKDCAE-----R 72
           PF CD CS +   +H     +R+ H  P+          D  T+   +FK   E     R
Sbjct: 331 PFKCDQCSYVASNQHEVTRHARQVHNGPKPLNCPH---CDYKTADRSNFKKHVELHVNPR 387

Query: 73  ELVAVICPYCEKNFC-LRHRHQSDHEC---EKLEIPKPRMAATQKLVKDIIDSKTGE 125
           +    +C Y     C L++  +S H     + +++ K ++  T+K   D+ D+ T E
Sbjct: 388 QFNCPVCDYAASKKCNLQYHFKSKHPTCPNKTMDVSKVKLKKTKKREADLPDNITNE 444


>gi|109150431 ring finger protein 31 [Homo sapiens]
          Length = 1072

 Score = 33.1 bits (74), Expect = 0.26
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 64  CSFKDCAERELVAVICPYCEKNFCLRHRHQSDHE 97
           CSF    ERE +   CP C + FC+R + Q + +
Sbjct: 802 CSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQ 835


>gi|11345484 zinc finger, AN1-type domain 3 [Homo sapiens]
          Length = 227

 Score = 32.7 bits (73), Expect = 0.34
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 6/73 (8%)

Query: 62  YPCSFK-DCAERELVAVICPYCEKNFCLRHRHQSDHECEKLEIPKPRMAATQKLVKDIID 120
           + C  K +  ++EL +  C Y    FC+ HR    H+C    + + R  A  K+VK  +D
Sbjct: 158 FQCQTKLELVQQELGSCRCGYV---FCMLHRLPEQHDCTFDHMGRGREEAIMKMVK--LD 212

Query: 121 SKTGETASKRWKG 133
            K G +  +  +G
Sbjct: 213 RKVGRSCQRIGEG 225


>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
           subunit [Homo sapiens]
          Length = 1091

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 8/104 (7%)

Query: 81  YCEKNFCLRHRHQSDHECEKLEI--PKPRMAATQKLVKDII-DSKTGETASKRWKG---- 133
           YC  +    HRH S  E  KL +   +P +   ++L+++++ D+         W      
Sbjct: 655 YCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALN 714

Query: 134 -AKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKE 176
            ++NS+   +VA +  +            E++  Q FL  G KE
Sbjct: 715 KSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKE 758


>gi|13430850 RB-associated KRAB repressor [Homo sapiens]
          Length = 714

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 13/67 (19%)

Query: 22  PFVCDDCSGIFCLE---------HRSRESHGCPEVTVINERLKTDQHTSY----PCSFKD 68
           P+ C++C   F L          H   +SH C E    ++   TD HT++    P    +
Sbjct: 456 PYECNECGKTFNLNSAFIRHRKVHTEEKSHECSECGKFSQLYLTDHHTAHLEEKPYECNE 515

Query: 69  CAERELV 75
           C +  LV
Sbjct: 516 CGKTFLV 522


>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 777

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 40/159 (25%), Positives = 56/159 (35%), Gaps = 32/159 (20%)

Query: 4   LDIGQHCQVEH-CRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQ---- 58
           L+ G  CQ  + C   D   F CD+C  + CL         C E     ERL+  +    
Sbjct: 12  LNPGLMCQESYACSGTDEAIFECDECCSLQCLR--------CEEELHRQERLRNHERIRL 63

Query: 59  ---HTSYPCSFKDCA-----ERELVAVICPYCEKNFCLRHRHQSDHECEKLEIP---KPR 107
              H  Y    K  +      R+   V C  C+ N CL        EC+K       K R
Sbjct: 64  KPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCL--------ECQKRTHSGGNKRR 115

Query: 108 MAATQKLVKDIIDSKTGETASKRWKGAKNSETAAKVALM 146
              T   V ++ +S   E   +  K  K +E      L+
Sbjct: 116 HPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLV 154


>gi|90652851 zinc finger transcription factor TRPS1 [Homo sapiens]
          Length = 1294

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 14/63 (22%)

Query: 32  FCLEHRSRESHGCPEVTVINERLKTDQ--HTSYPCSFKDCAERELVAVICPYCEKNFCLR 89
           FC + R  +SHG P+V V+   L+  Q  H  + C+ K C          P+C +  C  
Sbjct: 540 FC-DFRYSKSHG-PDVIVVGPLLRHYQQLHNIHKCTIKHC----------PFCPRGLCSP 587

Query: 90  HRH 92
            +H
Sbjct: 588 EKH 590


>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
          Length = 993

 Score = 28.5 bits (62), Expect = 6.4
 Identities = 11/22 (50%), Positives = 12/22 (54%)

Query: 25  CDDCSGIFCLEHRSRESHGCPE 46
           C  CS  +CL H   E HGC E
Sbjct: 913 CQLCSRRYCLSHHLPEIHGCGE 934


>gi|110815807 zinc finger protein 169 [Homo sapiens]
          Length = 603

 Score = 28.5 bits (62), Expect = 6.4
 Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 5/84 (5%)

Query: 22  PFVCDDCSGIFC-----LEHRSRESHGCPEVTVINERLKTDQHTSYPCSFKDCAERELVA 76
           PFVC +C   FC     L+H+S  +   P + +   R    Q            E+  V 
Sbjct: 345 PFVCPECGRGFCQKASLLQHQSSHTGERPFLCLECGRSFRQQSLLLSHQVTHSGEKPYVC 404

Query: 77  VICPYCEKNFCLRHRHQSDHECEK 100
             C +  +      RHQ  H  EK
Sbjct: 405 AECGHSFRQKVTLIRHQRTHTGEK 428


>gi|194097339 zinc finger protein 222 isoform 1 [Homo sapiens]
          Length = 491

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 33/96 (34%)

Query: 9   HCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHTSYPCSFKD 68
           HC++ H R++   P+ C+ C   F    + ++ H          R+ T +       FK 
Sbjct: 259 HCKL-HMREK---PYNCEKCGKAFMHNFQLQKHH----------RIHTGEKP-----FK- 298

Query: 69  CAERELVAVICPYCEKNFCLR---HRHQSDHECEKL 101
                     C  C K+FCLR   +RH   H  EKL
Sbjct: 299 ----------CEICGKSFCLRSSLNRHCMVHTAEKL 324


>gi|194018453 zinc finger protein 222 isoform 2 [Homo sapiens]
          Length = 451

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 33/96 (34%)

Query: 9   HCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHTSYPCSFKD 68
           HC++ H R++   P+ C+ C   F    + ++ H          R+ T +       FK 
Sbjct: 219 HCKL-HMREK---PYNCEKCGKAFMHNFQLQKHH----------RIHTGEKP-----FK- 258

Query: 69  CAERELVAVICPYCEKNFCLR---HRHQSDHECEKL 101
                     C  C K+FCLR   +RH   H  EKL
Sbjct: 259 ----------CEICGKSFCLRSSLNRHCMVHTAEKL 284


>gi|33354279 hypothetical protein LOC55425 [Homo sapiens]
          Length = 340

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 94  SDHECEKLEIPKPRMAATQKLVKDIIDSKTGETASK--RWKGAKNSETAAKVALMKLKMH 151
           +D E +  E  + R ++++K  + I+  +    A +   +  +K SE+   +   KLK  
Sbjct: 228 ADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSK 287

Query: 152 ADGDKSLPQTERIYF 166
           A  DK+ PQ ERI F
Sbjct: 288 AAEDKNKPQ-ERIPF 301


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,914,820
Number of Sequences: 37866
Number of extensions: 482736
Number of successful extensions: 1336
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1314
Number of HSP's gapped (non-prelim): 29
length of query: 268
length of database: 18,247,518
effective HSP length: 100
effective length of query: 168
effective length of database: 14,460,918
effective search space: 2429434224
effective search space used: 2429434224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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