Search of human proteins with 13325075

Search of human proteins with 13325075

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
sapiens]
         (747 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap...  1524   0.0  
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap...  1231   0.0  
gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]          464   e-130
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ...    64   5e-10
gi|5031973 protein disulfide isomerase A6 [Homo sapiens]               62   2e-09
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]    60   6e-09
gi|4758304 protein disulfide isomerase A4 [Homo sapiens]               58   4e-08
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s...    58   4e-08
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap...    57   5e-08
gi|94966757 protein disulfide isomerase A2 [Homo sapiens]              56   1e-07
gi|38505222 thioredoxin domain containing 10 [Homo sapiens]            52   3e-06
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s...    51   4e-06
gi|5803121 protein disulfide isomerase A5 [Homo sapiens]               47   5e-05
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa...    39   0.018
gi|148236531 hypothetical protein LOC339779 [Homo sapiens]             38   0.039
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    35   0.19 
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    35   0.19 
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              35   0.33 
gi|151101292 thioredoxin domain containing 1 [Homo sapiens]            35   0.33 
gi|153792074 proline rich 12 [Homo sapiens]                            35   0.33 
gi|117190342 PHD finger protein 2 [Homo sapiens]                       34   0.43 
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]              34   0.43 
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]     34   0.43 
gi|21361403 thioredoxin 2 precursor [Homo sapiens]                     34   0.57 
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul...    34   0.57 
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    34   0.57 
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    33   0.74 
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa...    33   0.74 
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi...    33   0.74 
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                33   0.74 

>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
           sapiens]
          Length = 747

 Score = 1524 bits (3946), Expect = 0.0
 Identities = 747/747 (100%), Positives = 747/747 (100%)

Query: 1   MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 60
           MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA
Sbjct: 1   MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 60

Query: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120
           WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT
Sbjct: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120

Query: 121 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 180
           VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF
Sbjct: 121 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 180

Query: 181 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 240
           ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL
Sbjct: 181 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 240

Query: 241 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 300
           FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY
Sbjct: 241 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 300

Query: 301 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 360
           MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR
Sbjct: 301 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 360

Query: 361 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 420
           QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR
Sbjct: 361 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 420

Query: 421 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 480
           QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS
Sbjct: 421 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 480

Query: 481 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 540
           HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI
Sbjct: 481 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 540

Query: 541 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 600
           ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG
Sbjct: 541 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 600

Query: 601 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN 660
           PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN
Sbjct: 601 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN 660

Query: 661 RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS 720
           RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS
Sbjct: 661 RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS 720

Query: 721 FMGLLAMYTYFQAKIRALKGHAGHPAA 747
           FMGLLAMYTYFQAKIRALKGHAGHPAA
Sbjct: 721 FMGLLAMYTYFQAKIRALKGHAGHPAA 747


>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
           sapiens]
          Length = 604

 Score = 1231 bits (3184), Expect = 0.0
 Identities = 602/602 (100%), Positives = 602/602 (100%)

Query: 1   MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 60
           MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA
Sbjct: 1   MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 60

Query: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120
           WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT
Sbjct: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120

Query: 121 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 180
           VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF
Sbjct: 121 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 180

Query: 181 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 240
           ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL
Sbjct: 181 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 240

Query: 241 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 300
           FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY
Sbjct: 241 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 300

Query: 301 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 360
           MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR
Sbjct: 301 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 360

Query: 361 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 420
           QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR
Sbjct: 361 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 420

Query: 421 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 480
           QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS
Sbjct: 421 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 480

Query: 481 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 540
           HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI
Sbjct: 481 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 540

Query: 541 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 600
           ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG
Sbjct: 541 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 600

Query: 601 PE 602
           PE
Sbjct: 601 PE 602


>gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]
          Length = 698

 Score =  464 bits (1194), Expect = e-130
 Identities = 252/611 (41%), Positives = 351/611 (57%), Gaps = 24/611 (3%)

Query: 12  PSLLLLLLWLLAVPGANAAPRSALY-SPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWC 70
           P LL+LL      PGA  A R  LY +  D + +L + +VRGA   S +AW V+F++SWC
Sbjct: 34  PRLLVLLAAAAVGPGAGGAAR--LYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWC 91

Query: 71  GHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKN 130
           GHCI +APTW+ALA DV+ W  A+ +AALDC EE N AVC D++I  +PT R+FKAFTK 
Sbjct: 92  GHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKE 151

Query: 131 -GSGAVFPVAGADVQTLRERLIDALESHHD-TWPPACPPLEPAKLEEIDGFFARNNEEYL 188
             +G  F     +++T+R+ +ID L++H + + PPACP L+P +  ++          Y+
Sbjct: 152 FTTGENFKGPDRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYV 211

Query: 189 ALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSR 248
           A++FE   SYLGREV LDL  ++ + V R L+ +   + K GV+  PSCYL++ NGS   
Sbjct: 212 AIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGL 271

Query: 249 VPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIYMADLESAL 308
           + V+   R+F+++YL+ L  + +++      P         VW+  D+SK+Y  DLES L
Sbjct: 272 INVVKPLRAFFSSYLKSLPDVRKKSLPLPEKPHKEENSEIVVWREFDKSKLYTVDLESGL 331

Query: 309 HYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPY 368
           HY+LR+E+     L G  L  LK FV VLAK FPGRP V+  L  + EWL     ++IPY
Sbjct: 332 HYLLRVELAAHKSLAGAELKTLKDFVTVLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPY 391

Query: 369 SFFKTALDD--RKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR--QNVD 424
           +     +++  R  G  L   + W+GCQGS    RG+PCSLW LFH LTV+A+     + 
Sbjct: 392 NAVLDLVNNKMRISGIFLTNHIKWVGCQGSRSELRGYPCSLWKLFHTLTVEASTHPDALV 451

Query: 425 HSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSSHNRV 484
            +      + VL  +R YVH FFGC++C  HFE+MA  SM  V +P+ A+LWLW  HN V
Sbjct: 452 GTGFEDDPQAVLQTMRRYVHTFFGCKECGEHFEEMAKESMDSVKTPDQAILWLWKKHNMV 511

Query: 485 NARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNIILDF 544
           N RLAG  SEDP+FPK+QWP  +LC ACH E   +  WD    L FLK H+   N++  +
Sbjct: 512 NGRLAGHLSEDPRFPKLQWPTPDLCPACHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTY 571

Query: 545 PAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVP--AEGPE 602
            A       D  + +    LA G    E     L P  PE+     +T    P  A GP 
Sbjct: 572 SA-------DQGDSSEGGTLARG----EEEEKRLTP--PEVSHGDRDTQSVRPPGALGPR 618

Query: 603 ASRPPKLHPGL 613
            + P  LH  L
Sbjct: 619 PALPESLHHSL 629



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 27/68 (39%), Positives = 37/68 (54%), Gaps = 4/68 (5%)

Query: 683 EGQLEARAGRGR----GQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYTYFQAKIRAL 738
           +G+L++  G G     G     LG  FS LD+SLCV LY  S + L+ MY +F+ + R  
Sbjct: 630 DGKLQSLDGPGAHKEVGGAAPFLGVDFSSLDMSLCVVLYVASSLFLMVMYFFFRVRSRRW 689

Query: 739 KGHAGHPA 746
           K    HPA
Sbjct: 690 KVKHHHPA 697


>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
           [Homo sapiens]
          Length = 432

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 69/252 (27%), Positives = 96/252 (38%), Gaps = 38/252 (15%)

Query: 59  SAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPA-LYLAALDCAEETNSAVCRDFNIPG 117
           +A  V FFA WCGHC    PTW  L +   +   A +Y+A +DC    +S VC    + G
Sbjct: 78  AAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCT--AHSDVCSAQGVRG 135

Query: 118 FPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPAC-PPLEPAKLEEI 176
           +PT++ FK     G  AV      D QTL   ++  L     T  P   PP  P   + +
Sbjct: 136 YPTLKLFKP----GQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGL 191

Query: 177 DGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVA---VRRVLNTEANVVRKFGVTD 233
               A N E ++A      G +  +  A      K +A    +  L  E +   K G  D
Sbjct: 192 YELSASNFELHVA-----QGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVD 246

Query: 234 FPSCYLLFRNGSVSRVPVLM------------------ESRSFYTAYLQRLSGLTREAAQ 275
               Y L     V   P L+                    R +  + LQR    T   A 
Sbjct: 247 CTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQR----TETGAT 302

Query: 276 TTVAPTTANKIA 287
            TV P+ A  +A
Sbjct: 303 ETVTPSEAPVLA 314



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 23/67 (34%), Positives = 39/67 (58%), Gaps = 2/67 (2%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           ++F+A WCGHC   APTW+ L++        + +A +DC  E N  +C  +++ G+PT+ 
Sbjct: 343 IKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERN--ICSKYSVRGYPTLL 400

Query: 123 FFKAFTK 129
            F+   K
Sbjct: 401 LFRGGKK 407



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 53/204 (25%), Positives = 91/204 (44%), Gaps = 30/204 (14%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           ++FFA WCGHC A APTW+ LA  ++     + +  +DC +  +  +C    + G+PT+ 
Sbjct: 210 IKFFAPWCGHCKALAPTWEQLALGLE-HSETVKIGKVDCTQ--HYELCSGNQVRGYPTLL 266

Query: 123 FFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHH----DTWPPACPPLEPAKLEEIDG 178
           +F    ++G          D+++LRE +   L+       +T  P+  P+  A+ E   G
Sbjct: 267 WF----RDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKG 322

Query: 179 FFARNNEEYLALIFEKGGSYL-------GREVAL-----DLSQHK-----GVAVRRV-LN 220
                 E        +G +++       G    L     +LS+ +     GV +  V   
Sbjct: 323 TVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCT 382

Query: 221 TEANVVRKFGVTDFPSCYLLFRNG 244
            E N+  K+ V  +P+  LLFR G
Sbjct: 383 AERNICSKYSVRGYPT-LLLFRGG 405


>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
          Length = 440

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 36/95 (37%), Positives = 48/95 (50%), Gaps = 4/95 (4%)

Query: 32  RSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVK-AW 90
           RS   S  D + L   D+    VL S   W VEF+A WCGHC    P W A A +VK   
Sbjct: 153 RSDSSSKKDVIELTD-DSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQT 211

Query: 91  RPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFK 125
           +  + LAA+D     N  +   + I GFPT++ F+
Sbjct: 212 KGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQ 244



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 31/92 (33%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 33  SALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRP 92
           + LYS SD +  L        V+ S S W VEF+A WCGHC    P WK  A    A + 
Sbjct: 18  NGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAA---TALKD 74

Query: 93  ALYLAALDCAEETNSAVCRDFNIPGFPTVRFF 124
            + + A+D   + + ++   + + GFPT++ F
Sbjct: 75  VVKVGAVDA--DKHHSLGGQYGVQGFPTIKIF 104


>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
          Length = 505

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 29/70 (41%), Positives = 40/70 (57%), Gaps = 5/70 (7%)

Query: 56  GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
           GS     VEFFA WCGHC   AP ++A A  +K   P   LA +DC   TN+  C  + +
Sbjct: 43  GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNT--CNKYGV 97

Query: 116 PGFPTVRFFK 125
            G+PT++ F+
Sbjct: 98  SGYPTLKIFR 107



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 37  SPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYL 96
           S   P+ ++ A+     V        +EF+A WCGHC    P +K L E +    P + +
Sbjct: 373 SNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVI 431

Query: 97  AALDCAEETNSAVCRDFNIPGFPTVRFFKAFTK 129
           A +D    T + V   + + GFPT+ F  A  K
Sbjct: 432 AKMDA---TANDVPSPYEVRGFPTIYFSPANKK 461


>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
          Length = 645

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 2/90 (2%)

Query: 36  YSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALY 95
           ++P   +TL+        V+       VEF+A WCGHC   AP ++  A+++    P + 
Sbjct: 172 WTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIP 231

Query: 96  LAALDCAEETNSAVCRDFNIPGFPTVRFFK 125
           LA +D   ET+ A  + F++ G+PT++ F+
Sbjct: 232 LAKVDATAETDLA--KRFDVSGYPTLKIFR 259



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           +EF+A WCGHC  FAP ++ +A  +K   P + +A +D    + S +   F++ G+PT++
Sbjct: 84  LEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDAT--SASVLASRFDVSGYPTIK 141

Query: 123 FFK 125
             K
Sbjct: 142 ILK 144



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 41  PLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALD 100
           P+ ++   T    V+  +    +EF+A WCGHC    P + +LA+  K  +  L +A +D
Sbjct: 526 PVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKG-QKGLVIAKMD 584

Query: 101 CAEETNSAVCRDFNIPGFPTVRF 123
                N      + + GFPT+ F
Sbjct: 585 AT--ANDVPSDRYKVEGFPTIYF 605


>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
           sapiens]
          Length = 508

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 26/63 (41%), Positives = 40/63 (63%), Gaps = 2/63 (3%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           VEF+A WCGHC A AP +   A  +KA    + LA +D  EE++ A  + + + G+PT++
Sbjct: 46  VEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLA--QQYGVRGYPTIK 103

Query: 123 FFK 125
           FF+
Sbjct: 104 FFR 106



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 5/86 (5%)

Query: 41  PLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALD 100
           P+ +L            +    VEF+A WCGHC   AP W  L E  K     + +A +D
Sbjct: 368 PVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKD-HENIVIAKMD 426

Query: 101 CAEETNSAVCRDFNIPGFPTVRFFKA 126
                  AV     +  FPT++FF A
Sbjct: 427 STANEVEAV----KVHSFPTLKFFPA 448


>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
           sapiens]
          Length = 324

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 23/67 (34%), Positives = 39/67 (58%), Gaps = 2/67 (2%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           ++F+A WCGHC   APTW+ L++        + +A +DC  E N  +C  +++ G+PT+ 
Sbjct: 235 IKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERN--ICSKYSVRGYPTLL 292

Query: 123 FFKAFTK 129
            F+   K
Sbjct: 293 LFRGGKK 299



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 53/204 (25%), Positives = 91/204 (44%), Gaps = 30/204 (14%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           ++FFA WCGHC A APTW+ LA  ++     + +  +DC +  +  +C    + G+PT+ 
Sbjct: 102 IKFFAPWCGHCKALAPTWEQLALGLE-HSETVKIGKVDCTQ--HYELCSGNQVRGYPTLL 158

Query: 123 FFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHH----DTWPPACPPLEPAKLEEIDG 178
           +F    ++G          D+++LRE +   L+       +T  P+  P+  A+ E   G
Sbjct: 159 WF----RDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKG 214

Query: 179 FFARNNEEYLALIFEKGGSYL-------GREVAL-----DLSQHK-----GVAVRRV-LN 220
                 E        +G +++       G    L     +LS+ +     GV +  V   
Sbjct: 215 TVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCT 274

Query: 221 TEANVVRKFGVTDFPSCYLLFRNG 244
            E N+  K+ V  +P+  LLFR G
Sbjct: 275 AERNICSKYSVRGYPT-LLLFRGG 297



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 54/216 (25%), Positives = 78/216 (36%), Gaps = 37/216 (17%)

Query: 94  LYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDA 153
           +Y+A +DC    +S VC    + G+PT++ FK     G  AV      D QTL   ++  
Sbjct: 6   VYVAKVDCT--AHSDVCSAQGVRGYPTLKLFKP----GQEAVKYQGPRDFQTLENWMLQT 59

Query: 154 LESHHDTWPPAC-PPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKG 212
           L     T  P   PP  P   + +    A N E ++A      G +  +  A      K 
Sbjct: 60  LNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVA-----QGDHFIKFFAPWCGHCKA 114

Query: 213 VA---VRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLM---------------- 253
           +A    +  L  E +   K G  D    Y L     V   P L+                
Sbjct: 115 LAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRD 174

Query: 254 --ESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIA 287
               R +  + LQR    T   A  TV P+ A  +A
Sbjct: 175 LESLREYVESQLQR----TETGATETVTPSEAPVLA 206


>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
          Length = 525

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 40/121 (33%), Positives = 55/121 (45%), Gaps = 10/121 (8%)

Query: 12  PSLLLLLLWLLAVPGANAAPRSALYSP-------SDPLTLLQADTVRGAVLGSRSAWAVE 64
           P LLLLLL      G     RS    P        D + +L   T+ G  L    A  VE
Sbjct: 7   PVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTL-GLALREHPALLVE 65

Query: 65  FFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFF 124
           F+A WCGHC A AP +   A  + A    + LA +D   +   A   +F +  +PT++FF
Sbjct: 66  FYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELA--EEFGVTEYPTLKFF 123

Query: 125 K 125
           +
Sbjct: 124 R 124



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 35/109 (32%), Positives = 51/109 (46%), Gaps = 12/109 (11%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           V+F+A WC HC   AP W+ALAE  +     + +A LD       A    F + GFPT++
Sbjct: 411 VKFYAPWCTHCKEMAPAWEALAEKYQD-HEDIIIAELDATANELDA----FAVHGFPTLK 465

Query: 123 FFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPA 171
           +F A    G   +   +  D++T  + L      +    P   PP EPA
Sbjct: 466 YFPA--GPGRKVIEYKSTRDLETFSKFL-----DNGGVLPTEEPPEEPA 507


>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
          Length = 454

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120
           W V+F+A WCGHC    P W  +  ++K+    + +  +D    + S++  +F + G+PT
Sbjct: 44  WLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDAT--SYSSIASEFGVRGYPT 101

Query: 121 VRFFK 125
           ++  K
Sbjct: 102 IKLLK 106


>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
           sapiens]
          Length = 793

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 5/82 (6%)

Query: 43  TLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCA 102
           T L   T    VL  ++ W ++F+A WCG C  FAP ++ LA  +K     +    +DC 
Sbjct: 673 TDLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKG---KVKAGKVDC- 728

Query: 103 EETNSAVCRDFNIPGFPTVRFF 124
            +  +  C+   I  +PTV+F+
Sbjct: 729 -QAYAQTCQKAGIRAYPTVKFY 749



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 53  AVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRD 112
           A + S   W V F++  C HC   APTW+  A++V      L + A++C ++    +CR 
Sbjct: 141 AAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDG---LLRIGAVNCGDD--RMLCRM 195

Query: 113 FNIPGFPTVRFFKA 126
             +  +P++  F++
Sbjct: 196 KGVNSYPSLFIFRS 209



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 5/64 (7%)

Query: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120
           W V+F++ WC  C    P WK +A  +      + + ++DC  +   + C   N+  +P 
Sbjct: 579 WMVDFYSPWCHPCQVLMPEWKRMARTLTG---LINVGSIDC--QQYHSFCAQENVQRYPE 633

Query: 121 VRFF 124
           +RFF
Sbjct: 634 IRFF 637



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 5/67 (7%)

Query: 58  RSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPG 117
           +  W V+FFA WC  C A  P  +  +  +      L    LDC    +  +C  +NI  
Sbjct: 468 KEPWLVDFFAPWCPPCRALLPELRRASNLLYG---QLKFGTLDCT--VHEGLCNMYNIQA 522

Query: 118 FPTVRFF 124
           +PT   F
Sbjct: 523 YPTTVVF 529


>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
          Length = 519

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 17/118 (14%)

Query: 59  SAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPAL-YLAALDCAEETNSAVCRDFNIPG 117
           S+  V F A WCGHC    P ++  AE +     +   LAA+D     N A+   F+I  
Sbjct: 294 SSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDAT--VNKALAERFHISE 351

Query: 118 FPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEE 175
           FPT+++F    KNG     PV        +++ ++ +++     P A PP EP   E+
Sbjct: 352 FPTLKYF----KNGEKYAVPVL-----RTKKKFLEWMQN-----PEAPPPPEPTWEEQ 395



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 1/62 (1%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122
           V F+A WC HC    P + A A+  K  R  +  AA+DC ++ N  +C+   + G+PT  
Sbjct: 419 VMFYAPWCPHCKKVIPHFTATADAFKDDRK-IACAAVDCVKDKNQDLCQQEAVKGYPTFH 477

Query: 123 FF 124
           ++
Sbjct: 478 YY 479



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 44/230 (19%), Positives = 73/230 (31%), Gaps = 63/230 (27%)

Query: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTV- 121
           + F+A WC  C    P ++  A  +   R    LA ++        +  ++++ GFPT+ 
Sbjct: 175 IMFYAPWCSMCKRMMPHFQKAATQL---RGHAVLAGMNVYSSEFENIKEEYSVRGFPTIC 231

Query: 122 -----RFFKAFTKNGS----------------------------GAVFPVAGADVQTLRE 148
                RF   +   GS                            G+V+ +   D     +
Sbjct: 232 YFEKGRFLFQYDNYGSTAEDIVEWLKNPQPPQPQVPETPWADEGGSVYHLTDEDFDQFVK 291

Query: 149 RLIDALESHHDTWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLS 208
                L   H  W   C  ++P                     FEK    L  E     +
Sbjct: 292 EHSSVLVMFHAPWCGHCKKMKPE--------------------FEKAAEALHGE-----A 326

Query: 209 QHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSF 258
              GV           +  +F +++FP+    F+NG    VPVL   + F
Sbjct: 327 DSSGVLAAVDATVNKALAERFHISEFPT-LKYFKNGEKYAVPVLRTKKKF 375


>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
          sapiens]
          Length = 349

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 3/76 (3%)

Query: 11 PPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWC 70
          P    LL  W+ AV  A A P  A   P    + +Q  T     L     W ++F+A WC
Sbjct: 8  PQLTALLAAWIAAV-AATAGPEEAALPPEQ--SRVQPMTASNWTLVMEGEWMLKFYAPWC 64

Query: 71 GHCIAFAPTWKALAED 86
            C      W+A A++
Sbjct: 65 PSCQQTDSEWEAFAKN 80


>gi|148236531 hypothetical protein LOC339779 [Homo sapiens]
          Length = 412

 Score = 37.7 bits (86), Expect = 0.039
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 13/73 (17%)

Query: 577 TLDPGKPEMMKSPTNTTPHVPAEGPEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQP 636
           +  P +P+      ++ PH P + P  S P +LH     +PG  PP H   L  N Q   
Sbjct: 127 SFSPSQPQ-----NSSLPHSPCQSP--SHPEELHSSTLTSPGPSPPSH--RLHSNRQ--- 174

Query: 637 LGQWHLSKRDTGA 649
             +WH   RDTG+
Sbjct: 175 TWRWH-QYRDTGS 186


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 30/166 (18%)

Query: 507 ELCSACHNERLDVPVWDVEATLNFLKAHFSPSNIIL----DFPAAGSAARRDVQNVAAAP 562
           ++ +  + + +DV  W+ E  LN  +  F P N +     DF   G+  ++     A   
Sbjct: 255 DIVTLINKDCIDVGWWEGE--LNGRRGVF-PDNFVKLLPPDFEKEGNRPKKPPPPSAPVI 311

Query: 563 ELAMGALELESRNSTLDPGKPEMMKSPTNTT-------------PHVPAEGPEASRPPKL 609
           +   G  E +     + P +PEM+ + T                P VPA  P+  RPPK 
Sbjct: 312 KQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDLQKPSVPAIPPKKPRPPKT 371

Query: 610 HPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAES 655
           +   R  PG  PP           E+P+G    ++ D+    LA S
Sbjct: 372 NSLSR--PGALPP--------RRPERPVGPLTHTRGDSPKIDLAGS 407


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 30/166 (18%)

Query: 507 ELCSACHNERLDVPVWDVEATLNFLKAHFSPSNIIL----DFPAAGSAARRDVQNVAAAP 562
           ++ +  + + +DV  W+ E  LN  +  F P N +     DF   G+  ++     A   
Sbjct: 292 DIVTLINKDCIDVGWWEGE--LNGRRGVF-PDNFVKLLPPDFEKEGNRPKKPPPPSAPVI 348

Query: 563 ELAMGALELESRNSTLDPGKPEMMKSPTNTT-------------PHVPAEGPEASRPPKL 609
           +   G  E +     + P +PEM+ + T                P VPA  P+  RPPK 
Sbjct: 349 KQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDLQKPSVPAIPPKKPRPPKT 408

Query: 610 HPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAES 655
           +   R  PG  PP           E+P+G    ++ D+    LA S
Sbjct: 409 NSLSR--PGALPP--------RRPERPVGPLTHTRGDSPKIDLAGS 444


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 34.7 bits (78), Expect = 0.33
 Identities = 30/96 (31%), Positives = 38/96 (39%), Gaps = 14/96 (14%)

Query: 558 VAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEGPEASRP--PKLHP-GLR 614
           VAAAP L  G     S +S      P   + P+   P  P E P  + P  PK+ P G  
Sbjct: 563 VAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG 622

Query: 615 AAPGQEPPEH-----------MAELQRNEQEQPLGQ 639
             P ++PP                 QR +QEQ L Q
Sbjct: 623 IGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQ 658


>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
          Length = 280

 Score = 34.7 bits (78), Expect = 0.33
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 8/63 (12%)

Query: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPAL--YLAALDCAEETNSAVCRDFNIPGF 118
           W +EF+A WC  C    P W++ AE    W   L   +A +D  E+    +   F I   
Sbjct: 47  WMIEFYAPWCPACQNLQPEWESFAE----WGEDLEVNIAKVDVTEQ--PGLSGRFIITAL 100

Query: 119 PTV 121
           PT+
Sbjct: 101 PTI 103


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 34.7 bits (78), Expect = 0.33
 Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 10/113 (8%)

Query: 580  PGKPEMMKSPTNTTPHVPAEGPEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQ 639
            P  P +   P    P  P   P A+ P    P   AAP  E PE           +PL  
Sbjct: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPE-------LPDTRPL-- 1546

Query: 640  WHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEARAGR 692
             HL+K+   AA+  E+  E     G    R       +  DIP  +L  + GR
Sbjct: 1547 -HLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGR 1598


>gi|117190342 PHD finger protein 2 [Homo sapiens]
          Length = 1096

 Score = 34.3 bits (77), Expect = 0.43
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 20/98 (20%)

Query: 531 LKAHFSPSNIILDFPA-------AGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKP 583
           L  HF PS +I D          A  A R +V  VA++ E+  G  E E   S ++   P
Sbjct: 422 LPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPP 481

Query: 584 EMM-------------KSPTNTTPHVPAEGPEASRPPK 608
           + +             K P  +    P + P+  RPPK
Sbjct: 482 QSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPK 519


>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
          Length = 422

 Score = 34.3 bits (77), Expect = 0.43
 Identities = 19/41 (46%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 6  SGSGPPPSL-LLLLLWLLAVPGANAAPRSALYSPSDPLTLL 45
          S   PPP L LLLLL +L  P A +   +A+ SP DP  L+
Sbjct: 12 SARRPPPLLPLLLLLCVLGAPRAGSGAHTAVISPQDPTLLI 52


>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
          Length = 659

 Score = 34.3 bits (77), Expect = 0.43
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 559 AAAPELAMGALELESRNSTL--DPGKPEMMKSPTNTTPHVPAEGPEASRPPKLHPGLRAA 616
           +  PEL    L L  R + L  D   P    +P    P   A+G +A R  +L P  RA 
Sbjct: 36  SGGPELEGDGLLLRERLAALGLDDPSPAEPGAPALRAPAAAAQG-QARRAAELSPEERAP 94

Query: 617 PGQEPPEHMAELQRNEQEQ 635
           PG+      AEL+  E E+
Sbjct: 95  PGRPGAPEAAELELEEDEE 113


>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
          Length = 166

 Score = 33.9 bits (76), Expect = 0.57
 Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 2   RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSA--LYSPSDPLT---LLQADTVRGAVLG 56
           R+ + G  PP +   L     +  G    P  A  +Y+    LT   +      +  V+ 
Sbjct: 17  RKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLTTFNIQDGPDFQDRVVN 76

Query: 57  SRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIP 116
           S +   V+F A WCG C    P    L + V      + +A +D  + T+ A+  ++ + 
Sbjct: 77  SETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLAI--EYEVS 131

Query: 117 GFPTVRFFK 125
             PTV   K
Sbjct: 132 AVPTVLAMK 140


>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
           [Homo sapiens]
          Length = 406

 Score = 33.9 bits (76), Expect = 0.57
 Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 21/117 (17%)

Query: 13  SLLLLLLWLLAVPGANAAPRSALYSP-SDPLTLLQADTVRGAVLGSRSAWAVEFFASWCG 71
           SLLLL+ W+              ++P +  +T L  + +   +L +     V F+A WC 
Sbjct: 15  SLLLLVTWV--------------FTPVTTEITSLDTENI-DEILNNADVALVNFYADWCR 59

Query: 72  HCIAFAPTWKALAEDVKAWRP---ALYLAALDCAEETNSAVCRDFNIPGFPTVRFFK 125
                 P ++  ++ +K   P    +  A +DC  + +S + + + I  +PT++ F+
Sbjct: 60  FSQMLHPIFEEASDVIKEEFPNENQVVFARVDC--DQHSDIAQRYRISKYPTLKLFR 114


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 33.9 bits (76), Expect = 0.57
 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 18/135 (13%)

Query: 569 LELESRNSTLDPGK-PEMMKSPTNTT----PHVPAEGPEASRPPK--LHPGLRAAPGQEP 621
           LE ES +  + P   P   +SP++      P  PA GP  +RPP+    P   A P  + 
Sbjct: 66  LEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDS 125

Query: 622 PEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVD- 680
           P    E+++  +   L +    +R+  A  LA  +A    +W   E +      KQL + 
Sbjct: 126 PPTKQEVKKAGERHKLAK---ERREERAKYLAAKKA----VWLEKEEKAKALREKQLQER 178

Query: 681 ---IPEGQLEARAGR 692
              + E +L+A   R
Sbjct: 179 RRRLEEQRLKAEQRR 193


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 33.5 bits (75), Expect = 0.74
 Identities = 54/223 (24%), Positives = 80/223 (35%), Gaps = 34/223 (15%)

Query: 483 RVNARLAGAPSEDPQFPKV-QWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNII 541
           R   +   A SE+  FP V +    E      NE  +  V + EAT+N        S+  
Sbjct: 681 RKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNE--EEMVEEAEATVN-------NSSDT 731

Query: 542 LDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKP----EMMKSPTNTTPHVP 597
              P+  + A +D       P   +GA           PG P    E + +PT  TP   
Sbjct: 732 ESIPSPHTEAAKDTGQNGPKPPATLGA-------DGPPPGPPTPPPEDIPAPTEPTPASE 784

Query: 598 AEGPEASRPPKLHPGLRAAPGQEPPEHMAE-------LQRNEQEQPLGQWHLSKRDTGAA 650
           A G  A  PP   P   A P   P E   E       ++  E+++P     L+     A 
Sbjct: 785 ATG--APTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAE 842

Query: 651 LLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRG 693
              +S   +    GP +    G+ ++      EG L+A    G
Sbjct: 843 EPVKSECTEEAEEGPAK----GKDAEAAEATAEGALKAEKKEG 881


>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
           sapiens]
          Length = 258

 Score = 33.5 bits (75), Expect = 0.74
 Identities = 13/27 (48%), Positives = 17/27 (62%)

Query: 58  RSAWAVEFFASWCGHCIAFAPTWKALA 84
           R  W VEFFA+W   C +FAP +  L+
Sbjct: 117 RVTWIVEFFANWSNDCQSFAPIYADLS 143


>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
           sapiens]
          Length = 296

 Score = 33.5 bits (75), Expect = 0.74
 Identities = 13/27 (48%), Positives = 17/27 (62%)

Query: 58  RSAWAVEFFASWCGHCIAFAPTWKALA 84
           R  W VEFFA+W   C +FAP +  L+
Sbjct: 155 RVTWIVEFFANWSNDCQSFAPIYADLS 181


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 33.5 bits (75), Expect = 0.74
 Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 10/71 (14%)

Query: 567  GALELESRNSTLDPGKPEMMKSPTNTTPHVPA----------EGPEASRPPKLHPGLRAA 616
            GA  +++  S   P  PE  +    TTP VPA            P     PK  PG RA 
Sbjct: 1755 GAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRAT 1814

Query: 617  PGQEPPEHMAE 627
            P +  P  +A+
Sbjct: 1815 PRKVAPPCLAQ 1825


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,190,483
Number of Sequences: 37866
Number of extensions: 1503396
Number of successful extensions: 6363
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 6207
Number of HSP's gapped (non-prelim): 191
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.