BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens] (740 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens] 1519 0.0 gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 137 5e-32 gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 137 5e-32 gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 137 5e-32 gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 136 8e-32 gi|13129006 nucleolar protein GU2 [Homo sapiens] 136 8e-32 gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 134 3e-31 gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 134 3e-31 gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 132 2e-30 gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 131 2e-30 gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 128 2e-29 gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 127 4e-29 gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 127 5e-29 gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 126 6e-29 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 124 2e-28 gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 123 7e-28 gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 123 7e-28 gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 123 7e-28 gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 120 5e-27 gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 119 1e-26 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 115 1e-25 gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 115 1e-25 gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 115 1e-25 gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 114 4e-25 gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [... 113 6e-25 gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H... 113 6e-25 gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 112 9e-25 gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 112 9e-25 gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [... 112 1e-24 gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 112 2e-24 >gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens] Length = 740 Score = 1519 bits (3933), Expect = 0.0 Identities = 740/740 (100%), Positives = 740/740 (100%) Query: 1 MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV 60 MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV Sbjct: 1 MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV 60 Query: 61 IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH 120 IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH Sbjct: 61 IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH 120 Query: 121 GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD 180 GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD Sbjct: 121 GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD 180 Query: 181 NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF 240 NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF Sbjct: 181 NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF 240 Query: 241 NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE 300 NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE Sbjct: 241 NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE 300 Query: 301 QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN 360 QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN Sbjct: 301 QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN 360 Query: 361 LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE 420 LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE Sbjct: 361 LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE 420 Query: 421 KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN 480 KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN Sbjct: 421 KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN 480 Query: 481 SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF 540 SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF Sbjct: 481 SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF 540 Query: 541 SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV 600 SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV Sbjct: 541 SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV 600 Query: 601 HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS 660 HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS Sbjct: 601 HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS 660 Query: 661 EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK 720 EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK Sbjct: 661 EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK 720 Query: 721 EAQTSFLHLGYLPNQLFRTF 740 EAQTSFLHLGYLPNQLFRTF Sbjct: 721 EAQTSFLHLGYLPNQLFRTF 740 >gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo sapiens] Length = 662 Score = 137 bits (344), Expect = 5e-32 Identities = 96/333 (28%), Positives = 156/333 (46%), Gaps = 58/333 (17%) Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346 P +L++ P+RELA Q ++F ++R ++ GG Q+ LE G ++V T Sbjct: 267 PISLVLAPTRELAVQIYEEARKFSY---RSRVRPCVVYGGADIGQQIRDLERGCHLLVAT 323 Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQ-VIV 405 PGRL D++ GK+ L ++LVLDEAD +L G+ I R+ + Q T K ++ ++ Sbjct: 324 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI---VEQDTMPPKGVRHTMM 380 Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465 SAT FP + + D + + + V V ++ + +++ Sbjct: 381 FSAT---------------FPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKV------ 419 Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQ-AIIFCRTKIDCDNLEQ 524 +W E K + + + D ++F TK D+LE Sbjct: 420 ------------------VWVEESD--KRSFLLDLLNATGKDSLTLVFVETKKGADSLED 459 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 + +G ++C +HGDR +R++ L +F+ G L+ T VAARG+DI V Sbjct: 460 FLYHEG---------YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNV 510 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAIS 617 +VIN LP + + YVHRIGR GR +GLA S Sbjct: 511 KHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 543 Score = 46.6 bits (109), Expect = 8e-05 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 6/82 (7%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 +FS++ + I +E + PT +Q +IP+I D++ A+TGSGKT AF +P++ Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240 Query: 63 IVY-----ETLKDQQE-GKKGK 78 +Y E L+ +E G+ G+ Sbjct: 241 QIYSDGPGEALRAMKENGRYGR 262 >gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 137 bits (344), Expect = 5e-32 Identities = 96/333 (28%), Positives = 157/333 (47%), Gaps = 58/333 (17%) Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346 P +L++ P+RELA Q ++F ++R ++ GG Q+ LE G ++V T Sbjct: 265 PISLVLAPTRELAVQIYEEARKFSY---RSRVRPCVVYGGADIGQQIRDLERGCHLLVAT 321 Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQ-VIV 405 PGRL D++ GK+ L ++LVLDEAD +L G+ I R+ + Q T K ++ ++ Sbjct: 322 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI---VEQDTMPPKGVRHTMM 378 Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465 SAT FP + + D + + + V V ++ + +++ Sbjct: 379 FSAT---------------FPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKV------ 417 Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQ-AIIFCRTKIDCDNLEQ 524 +W E + K + + + D ++F TK D+LE Sbjct: 418 ------------------VWVEDLD--KRSFLLDILGATGSDSLTLVFVETKKGADSLED 457 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 + +G ++C +HGDR +R++ L +F+ G L+ T VAARG+DI V Sbjct: 458 FLYHEG---------YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNV 508 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAIS 617 +VIN LP + + YVHRIGR GR +GLA S Sbjct: 509 RHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 541 Score = 50.1 bits (118), Expect = 8e-06 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 6/81 (7%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63 FS++ + I +E + PT +Q +IP+I G D++ A+TGSGKT AF +P++ Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239 Query: 64 VY-----ETLKDQQE-GKKGK 78 +Y E LK +E G+ G+ Sbjct: 240 IYTDGPGEALKAVKENGRYGR 260 >gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 137 bits (344), Expect = 5e-32 Identities = 96/333 (28%), Positives = 157/333 (47%), Gaps = 58/333 (17%) Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346 P +L++ P+RELA Q ++F ++R ++ GG Q+ LE G ++V T Sbjct: 265 PISLVLAPTRELAVQIYEEARKFSY---RSRVRPCVVYGGADIGQQIRDLERGCHLLVAT 321 Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQ-VIV 405 PGRL D++ GK+ L ++LVLDEAD +L G+ I R+ + Q T K ++ ++ Sbjct: 322 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI---VEQDTMPPKGVRHTMM 378 Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465 SAT FP + + D + + + V V ++ + +++ Sbjct: 379 FSAT---------------FPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKV------ 417 Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQ-AIIFCRTKIDCDNLEQ 524 +W E + K + + + D ++F TK D+LE Sbjct: 418 ------------------VWVEDLD--KRSFLLDILGATGSDSLTLVFVETKKGADSLED 457 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 + +G ++C +HGDR +R++ L +F+ G L+ T VAARG+DI V Sbjct: 458 FLYHEG---------YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNV 508 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAIS 617 +VIN LP + + YVHRIGR GR +GLA S Sbjct: 509 RHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 541 Score = 50.1 bits (118), Expect = 8e-06 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 6/81 (7%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63 FS++ + I +E + PT +Q +IP+I G D++ A+TGSGKT AF +P++ Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239 Query: 64 VY-----ETLKDQQE-GKKGK 78 +Y E LK +E G+ G+ Sbjct: 240 IYTDGPGEALKAVKENGRYGR 260 >gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sapiens] Length = 648 Score = 136 bits (342), Expect = 8e-32 Identities = 105/353 (29%), Positives = 161/353 (45%), Gaps = 80/353 (22%) Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344 N P L++ P+RELA Q ++ LR + + GG +Q+ L+ GVDI++ Sbjct: 315 NRPGMLVLTPTRELALQVEGECCKYSY----KGLRSVCVYGGGNRDEQIEELKKGVDIII 370 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 TPGRL+DL + +NL + +LVLDEAD +L G+ PQ+ ++++ Sbjct: 371 ATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFE----------PQI------MKIL 414 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 + DV+ + +M TW P +VH RL +S++ Sbjct: 415 L--------DVRPDRQTVMTSATW---------PHSVH---------------RLAQSYL 442 Query: 465 R--------TDDVHAKDNTRPG---ANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFC 513 + T D+ A + + E WS L+ + D+ I+F Sbjct: 443 KEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSST--------DKVIVFV 494 Query: 514 RTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTD 573 K D+L I S LHGDR+ +R++ LE FK G VR LI TD Sbjct: 495 SRKAVADHLSSDLILGN---------ISVESLHGDREQRDREKALENFKTGKVRILIATD 545 Query: 574 VAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKV 626 +A+RG+D+H V +V N P + YVHRIGR GRA R G++I+ + +V Sbjct: 546 LASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRV 598 Score = 42.4 bits (98), Expect = 0.002 Identities = 20/64 (31%), Positives = 42/64 (65%), Gaps = 2/64 (3%) Query: 11 PEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIP--VIQIVYETL 68 PE+ + +++ + PT IQ+++ P++L G D++ A+TG+GKT + +P + ++ +L Sbjct: 251 PEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSL 310 Query: 69 KDQQ 72 K Q+ Sbjct: 311 KGQR 314 >gi|13129006 nucleolar protein GU2 [Homo sapiens] Length = 737 Score = 136 bits (342), Expect = 8e-32 Identities = 96/333 (28%), Positives = 161/333 (48%), Gaps = 56/333 (16%) Query: 286 APKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVG 345 +PK L++ P+RELA Q + K + KL GG + + Q++ + NG+DI+VG Sbjct: 211 SPKVLVLAPTRELANQVAKDFKDITR-----KLSVACFYGGTSYQSQINHIRNGIDILVG 265 Query: 346 TPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIV 405 TPGR+ D + +G+L+LS++R +VLDE D +L G+++ + + ++ + S+ Q ++ Sbjct: 266 TPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNP-QTLL 324 Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGE--DSVPDTVHHVVVPVNPKTDRLWERLGKSH 463 SAT + K + + VDL G+ TV H+ + + W Sbjct: 325 FSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCH------W------- 371 Query: 464 IRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE 523 + P + + +++ G +AIIFC TK + + Sbjct: 372 ---------------SQRPAVIGDVLQVYSGSEG----------RAIIFCETKKNVTEMA 406 Query: 524 QYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHG 583 P K + CLHGD +R+ L+ F++G + L+ T+VAARG+DI Sbjct: 407 M-------NPHIKQ---NAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPE 456 Query: 584 VPYVINVTLPDEKQNYVHRIGRVGRAERMGLAI 616 V VI + P + ++Y+HR GR GRA R G+ I Sbjct: 457 VDLVIQSSPPQDVESYIHRSGRTGRAGRTGICI 489 Score = 34.7 bits (78), Expect = 0.33 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 AFS + E + ++ IQ ++ + G D++ A TG+GKT +F+IP+I+ Sbjct: 138 AFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIE 197 Query: 63 IV---YETLKDQQEGK 75 + ET+K + K Sbjct: 198 RLQRNQETIKKSRSPK 213 >gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] Length = 731 Score = 134 bits (337), Expect = 3e-31 Identities = 97/331 (29%), Positives = 157/331 (47%), Gaps = 55/331 (16%) Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344 + P L++ P+RELA+Q + K +L+ I GG Q+ LE GV+I + Sbjct: 243 DGPICLVLAPTRELAQQVQQVADDYGKC---SRLKSTCIYGGAPKGPQIRDLERGVEICI 299 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 TPGRL D + +GK NL + +LVLDEAD +L G+ I ++ + Q+ D Q + Sbjct: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKI---VDQIRPDR---QTL 353 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 + SAT +V++L+E + T +++ ++ + +H ++ + Sbjct: 354 MWSATWPK-EVRQLAEDFLRDYTQINV---GNLELSANHNILQI---------------- 393 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524 ++ E+ K K + I K ++ IIF TK CD+L + Sbjct: 394 -----------------VDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTR 436 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 + G + +C+HGD+ ER L F+ G LI TDVA+RG+D+ V Sbjct: 437 RMRRDG---------WPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDV 487 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLA 615 +VIN P+ ++YVHRIGR R+ G A Sbjct: 488 KFVINYDYPNSSEDYVHRIGRTARSTNKGTA 518 Score = 41.6 bits (96), Expect = 0.003 Identities = 21/59 (35%), Positives = 31/59 (52%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 AF + + + + PT IQ + PL L G D++ A+TGSGKT A+ +P I Sbjct: 172 AFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230 >gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] Length = 729 Score = 134 bits (337), Expect = 3e-31 Identities = 97/331 (29%), Positives = 157/331 (47%), Gaps = 55/331 (16%) Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344 + P L++ P+RELA+Q + K +L+ I GG Q+ LE GV+I + Sbjct: 243 DGPICLVLAPTRELAQQVQQVADDYGKC---SRLKSTCIYGGAPKGPQIRDLERGVEICI 299 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 TPGRL D + +GK NL + +LVLDEAD +L G+ I ++ + Q+ D Q + Sbjct: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKI---VDQIRPDR---QTL 353 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 + SAT +V++L+E + T +++ ++ + +H ++ + Sbjct: 354 MWSATWPK-EVRQLAEDFLRDYTQINV---GNLELSANHNILQI---------------- 393 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524 ++ E+ K K + I K ++ IIF TK CD+L + Sbjct: 394 -----------------VDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTR 436 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 + G + +C+HGD+ ER L F+ G LI TDVA+RG+D+ V Sbjct: 437 RMRRDG---------WPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDV 487 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLA 615 +VIN P+ ++YVHRIGR R+ G A Sbjct: 488 KFVINYDYPNSSEDYVHRIGRTARSTNKGTA 518 Score = 41.6 bits (96), Expect = 0.003 Identities = 21/59 (35%), Positives = 31/59 (52%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 AF + + + + PT IQ + PL L G D++ A+TGSGKT A+ +P I Sbjct: 172 AFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230 >gi|21071032 DEAD-box protein abstrakt [Homo sapiens] Length = 622 Score = 132 bits (331), Expect = 2e-30 Identities = 101/348 (29%), Positives = 169/348 (48%), Gaps = 64/348 (18%) Query: 279 QTKFLP----NAPKALIVEPSRELAEQTLNNIKQFKKYID---NPKLRELLIIGGVAARD 331 Q K LP P LI+ PSRELA QT ++ + + + +P LR L IGG++ ++ Sbjct: 246 QEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKE 305 Query: 332 QLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQI 391 Q+ + +GV ++V TPGRL DL+ ++L R+L LDEAD ++ G+ I + + Sbjct: 306 QMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYF 365 Query: 392 PQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPK 451 G+R Q ++ SAT+ +KI +F +K P T++ Sbjct: 366 K-----GQR-QTLLFSATM--------PKKIQNFAKSALVK-----PVTIN--------- 397 Query: 452 TDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAII 511 +G++ + DV E E K++ Y + +++ +I Sbjct: 398 -------VGRAGAASLDV---------IQEVEYVKEEAKMV---YLLECLQKTP-PPVLI 437 Query: 512 FCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLIC 571 F K D D + +Y + +G V +HG + ER + +E F++G L+ Sbjct: 438 FAEKKADVDAIHEYLLLKG---------VEAVAIHGGKDQEERTKAIEAFREGKKDVLVA 488 Query: 572 TDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619 TDVA++G+D + +VIN +P+E +NYVHRIGR GR+ G+A + + Sbjct: 489 TDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFI 536 Score = 47.4 bits (111), Expect = 5e-05 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 4/79 (5%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 +F EM I + +++ PT IQ + IP IL G D++ A TGSGKT F++PVI Sbjct: 182 SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIM 241 Query: 63 IVYETLK----DQQEGKKG 77 E K ++EG G Sbjct: 242 FCLEQEKRLPFSKREGPYG 260 >gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] Length = 614 Score = 131 bits (330), Expect = 2e-30 Identities = 98/334 (29%), Positives = 153/334 (45%), Gaps = 61/334 (18%) Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344 + P L++ P+RELA+Q ++ + +L+ I GG Q+ LE GV+I + Sbjct: 166 DGPICLVLAPTRELAQQVQQVAAEYCRAC---RLKSTCIYGGAPKGPQIRDLERGVEICI 222 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 TPGRL D + GK NL + +LVLDEAD +L G+ I ++ + Q+ D Q + Sbjct: 223 ATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKI---VDQIRPDR---QTL 276 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 + SAT +P V ED + D +H + + L +H Sbjct: 277 MWSAT---------------WPKEVRQLAEDFLKDYIHINIGALE---------LSANH- 311 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKE---HKMDQAIIFCRTKIDCDN 521 N ++ + K E +R ++E K ++ I+F TK CD Sbjct: 312 ---------------NILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDE 356 Query: 522 LEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI 581 L + + G + + +HGD+ ER L FK G LI TDVA+RG+D+ Sbjct: 357 LTRKMRRDG---------WPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDV 407 Query: 582 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLA 615 V +VIN P+ ++Y+HRIGR R+ + G A Sbjct: 408 EDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTA 441 Score = 41.2 bits (95), Expect = 0.004 Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIP-VIQ 62 F E + + ++ PT IQA+ P+ L G D++ A+TGSGKT ++ +P ++ Sbjct: 96 FYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVH 155 Query: 63 IVYETLKDQQEG 74 I ++ ++ +G Sbjct: 156 INHQPFLERGDG 167 >gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapiens] Length = 783 Score = 128 bits (322), Expect = 2e-29 Identities = 96/339 (28%), Positives = 155/339 (45%), Gaps = 52/339 (15%) Query: 286 APKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVG 345 AP+ L++ P+RELA Q + K KL GG Q + NG+DI+VG Sbjct: 260 APQVLVLAPTRELANQVSKDFSDITK-----KLSVACFYGGTPYGGQFERMRNGIDILVG 314 Query: 346 TPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIV 405 TPGR+ D + GKL+L++++ +VLDE D +L G++D + + + + S+ Q ++ Sbjct: 315 TPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNP-QTLL 373 Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465 SAT P WV + + T V D + ++ K+ I Sbjct: 374 FSATC---------------PHWVFNVAKKYMKSTYEQV--------DLIGKKTQKTAIT 410 Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQY 525 + + K + W++ ++ +R H+ + IIFC TK + L Q Sbjct: 411 VEHLAIKCH----------WTQRAAVIGD--VIRVYSGHQ-GRTIIFCETKKEAQELSQ- 456 Query: 526 FIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVP 585 + LHGD +R+ L+ F+ G L+ T+VAARG+DI V Sbjct: 457 ---------NSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVD 507 Query: 586 YVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624 VI + P + ++Y+HR GR GRA R G+ I ++E Sbjct: 508 LVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEE 546 Score = 43.1 bits (100), Expect = 0.001 Identities = 22/73 (30%), Positives = 42/73 (57%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 AFS + E + ++ IQA++ + G D++ A TG+GKT +F+IP+I+ Sbjct: 187 AFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIE 246 Query: 63 IVYETLKDQQEGK 75 ++ L+D++ G+ Sbjct: 247 KLHGELQDRKRGR 259 >gi|83700235 eukaryotic translation initiation factor 4A2 [Homo sapiens] Length = 407 Score = 127 bits (319), Expect = 4e-29 Identities = 107/359 (29%), Positives = 166/359 (46%), Gaps = 64/359 (17%) Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLE-NGVDIVVGT 346 +AL++ P+RELA+Q I Y+ IGG R+++ L+ IVVGT Sbjct: 103 QALVLAPTRELAQQIQKVILALGDYMGATCHA---CIGGTNVRNEMQKLQAEAPHIVVGT 159 Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVC 406 PGR+ D+++ L+ ++ VLDEAD +LS+G+ D I + ++ +QV++ Sbjct: 160 PGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKL------NTSIQVVLL 213 Query: 407 SATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRT 466 SAT+ + DV ++++K M P + +K E+ + + + V ER Sbjct: 214 SATMPT-DVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINV--------ER-------- 256 Query: 467 DDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYF 526 E W + L Y I QA+IF T+ D L + Sbjct: 257 ----------------EEWK--LDTLCDLYETLTIT-----QAVIFLNTRRKVDWLTEKM 293 Query: 527 IQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPY 586 F+ LHGD ER + F+ G R LI TD+ ARGID+ V Sbjct: 294 ---------HARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSL 344 Query: 587 VINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKE 645 VIN LP ++NY+HRIGR GR R G+AI+ V E +++ + + YNT ++E Sbjct: 345 VINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI-----ETFYNTTVEE 398 Score = 37.7 bits (86), Expect = 0.039 Identities = 19/69 (27%), Positives = 37/69 (53%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63 F +M + + + + + P+ IQ +I + G DV+ A++G+GKT F+I ++Q Sbjct: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94 Query: 64 VYETLKDQQ 72 + K+ Q Sbjct: 95 LEIEFKETQ 103 >gi|4503529 eukaryotic translation initiation factor 4A isoform 1 [Homo sapiens] Length = 406 Score = 127 bits (318), Expect = 5e-29 Identities = 107/361 (29%), Positives = 166/361 (45%), Gaps = 64/361 (17%) Query: 286 APKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLE-NGVDIVV 344 A +AL++ P+RELA+Q + Y+ IGG R ++ L+ I+V Sbjct: 100 ATQALVLAPTRELAQQIQKVVMALGDYMGASCHA---CIGGTNVRAEVQKLQMEAPHIIV 156 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 GTPGR+ D+++ L+ ++ VLDEAD +LS+G+ D I + ++ T QV+ Sbjct: 157 GTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT------QVV 210 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 + SAT+ S DV ++++K M P + +K E+ + + + V ER Sbjct: 211 LLSATMPS-DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV--------ER------ 255 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524 E W + L Y I QA+IF T+ D L + Sbjct: 256 ------------------EEWK--LDTLCDLYETLTIT-----QAVIFINTRRKVDWLTE 290 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 F+ +HGD ER + F+ G R LI TD+ ARGID+ V Sbjct: 291 KM---------HARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQV 341 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLK 644 VIN LP ++NY+HRIGR GR R G+AI++V E ++ + + YNT ++ Sbjct: 342 SLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI-----ETFYNTSIE 396 Query: 645 E 645 E Sbjct: 397 E 397 Score = 38.9 bits (89), Expect = 0.017 Identities = 20/70 (28%), Positives = 38/70 (54%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 +F +M + + + + + P+ IQ +I + G DV+ A++G+GKT F+I ++Q Sbjct: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92 Query: 63 IVYETLKDQQ 72 + LK Q Sbjct: 93 QIELDLKATQ 102 >gi|7661920 eukaryotic translation initiation factor 4A, isoform 3 [Homo sapiens] Length = 411 Score = 126 bits (317), Expect = 6e-29 Identities = 99/339 (29%), Positives = 158/339 (46%), Gaps = 58/339 (17%) Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347 +ALI+ P+RELA Q + Y++ ++ IGG + + L+ G +V GTP Sbjct: 108 QALILAPTRELAVQIQKGLLALGDYMN---VQCHACIGGTNVGEDIRKLDYGQHVVAGTP 164 Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407 GR+ D++ L ++ LVLDEAD +L++G+ + I ++ +P T QV++ S Sbjct: 165 GRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT------QVVLIS 218 Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTD 467 ATL ++ +++ K M P + +K ++ + + V V ER Sbjct: 219 ATL-PHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAV--------ER--------- 260 Query: 468 DVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFI 527 E W L Y I QA+IFC TK D L + Sbjct: 261 ---------------EEWK--FDTLCDLYDTLTIT-----QAVIFCNTKRKVDWLTEKMR 298 Query: 528 QQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYV 587 + F+ +HGD ER+ ++ F+ G R LI TDV ARG+D+ V + Sbjct: 299 EAN---------FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349 Query: 588 INVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKV 626 IN LP+ ++ Y+HRIGR GR R G+AI+ V + ++ Sbjct: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRI 388 Score = 43.1 bits (100), Expect = 0.001 Identities = 21/69 (30%), Positives = 40/69 (57%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63 F MG+ ++ + + + P+ IQ +I I+ G DV+ +++G+GKT FSI V+Q Sbjct: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 Query: 64 VYETLKDQQ 72 + +++ Q Sbjct: 100 LDIQVRETQ 108 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 124 bits (312), Expect = 2e-28 Identities = 104/351 (29%), Positives = 158/351 (45%), Gaps = 47/351 (13%) Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346 P A+I+ P+RELA+Q +F K + +R + +IGG++ DQ L G +IV+ T Sbjct: 469 PYAIILAPTRELAQQIEEETIKFGKPLG---IRTVAVIGGISREDQGFRLRMGCEIVIAT 525 Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVC 406 PGRL D++ L LS+ ++VLDEAD ++ G+ + ++ +P + Sbjct: 526 PGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDP 585 Query: 407 SATLHSFDV--KKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 L +F+ K + +M T +P V ERL +S++ Sbjct: 586 EKMLANFESGKHKYRQTVMFTAT---------MPPAV---------------ERLARSYL 621 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVR----AIKEHKMDQAII-FCRTKIDC 519 R V + A P E L E R AI E D II F K C Sbjct: 622 RRPAVVYIGS----AGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGC 677 Query: 520 DNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGI 579 D L + + G ++ LHG + +R+ L K G L+ TDVA RGI Sbjct: 678 DVLAKSLEKMG---------YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGI 728 Query: 580 DIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHV 630 DI V V+N + ++Y+HRIGR GRA + G+AI+ + E V+Y + Sbjct: 729 DIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYEL 779 Score = 49.3 bits (116), Expect = 1e-05 Identities = 22/59 (37%), Positives = 38/59 (64%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 ++ + + P I + +++ + PT IQ ++IP+ L D++ AETGSGKT AF IP++ Sbjct: 392 SWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLL 450 >gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 [Homo sapiens] Length = 724 Score = 123 bits (308), Expect = 7e-28 Identities = 97/355 (27%), Positives = 163/355 (45%), Gaps = 55/355 (15%) Query: 271 HSGNAQVTQTKFLP-NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAA 329 H + +T ++F P+ +IV P+REL Q + +K+ +R ++I GG Sbjct: 349 HMMHDGITASRFKELQEPECIIVAPTRELVNQIY---LEARKFSFGTCVRAVVIYGGTQL 405 Query: 330 RDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHN 389 + + G +I+ TPGRL D++ K+ L Q+++LVLDEAD +L G+ + ++ + Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 465 Query: 390 QIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVN 449 P + S +R Q ++ SAT ++++L+ + + Sbjct: 466 -CPGMPSKEQR-QTLMFSATFPE-EIQRLAAEFL-------------------------- 496 Query: 450 PKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQA 509 K++ L+ +G+ DV + + + K E V ++ ++ Sbjct: 497 -KSNYLFVAVGQVGGACRDVQ------------QTVLQVGQFSKREKLVEILRNIGDERT 543 Query: 510 IIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFL 569 ++F TK D + + Q+ + S +HGDR+ ER+Q L F+ G L Sbjct: 544 MVFVETKKKADFIATFLCQE---------KISTTSIHGDREQREREQALGDFRFGKCPVL 594 Query: 570 ICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624 + T VAARG+DI V +VIN LP YVHRIGR GR G AIS E + Sbjct: 595 VATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESD 649 Score = 46.2 bits (108), Expect = 1e-04 Identities = 21/58 (36%), Positives = 34/58 (58%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 F E + + + + + T +Q SIP+IL G D++ A+TGSGKT AF +P++ Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347 >gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [Homo sapiens] Length = 724 Score = 123 bits (308), Expect = 7e-28 Identities = 97/355 (27%), Positives = 163/355 (45%), Gaps = 55/355 (15%) Query: 271 HSGNAQVTQTKFLP-NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAA 329 H + +T ++F P+ +IV P+REL Q + +K+ +R ++I GG Sbjct: 349 HMMHDGITASRFKELQEPECIIVAPTRELVNQIY---LEARKFSFGTCVRAVVIYGGTQL 405 Query: 330 RDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHN 389 + + G +I+ TPGRL D++ K+ L Q+++LVLDEAD +L G+ + ++ + Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 465 Query: 390 QIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVN 449 P + S +R Q ++ SAT ++++L+ + + Sbjct: 466 -CPGMPSKEQR-QTLMFSATFPE-EIQRLAAEFL-------------------------- 496 Query: 450 PKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQA 509 K++ L+ +G+ DV + + + K E V ++ ++ Sbjct: 497 -KSNYLFVAVGQVGGACRDVQ------------QTVLQVGQFSKREKLVEILRNIGDERT 543 Query: 510 IIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFL 569 ++F TK D + + Q+ + S +HGDR+ ER+Q L F+ G L Sbjct: 544 MVFVETKKKADFIATFLCQE---------KISTTSIHGDREQREREQALGDFRFGKCPVL 594 Query: 570 ICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624 + T VAARG+DI V +VIN LP YVHRIGR GR G AIS E + Sbjct: 595 VATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESD 649 Score = 46.2 bits (108), Expect = 1e-04 Identities = 21/58 (36%), Positives = 34/58 (58%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 F E + + + + + T +Q SIP+IL G D++ A+TGSGKT AF +P++ Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347 >gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 [Homo sapiens] Length = 690 Score = 123 bits (308), Expect = 7e-28 Identities = 97/355 (27%), Positives = 163/355 (45%), Gaps = 55/355 (15%) Query: 271 HSGNAQVTQTKFLP-NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAA 329 H + +T ++F P+ +IV P+REL Q + +K+ +R ++I GG Sbjct: 315 HMMHDGITASRFKELQEPECIIVAPTRELVNQIY---LEARKFSFGTCVRAVVIYGGTQL 371 Query: 330 RDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHN 389 + + G +I+ TPGRL D++ K+ L Q+++LVLDEAD +L G+ + ++ + Sbjct: 372 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 431 Query: 390 QIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVN 449 P + S +R Q ++ SAT ++++L+ + + Sbjct: 432 -CPGMPSKEQR-QTLMFSATFPE-EIQRLAAEFL-------------------------- 462 Query: 450 PKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQA 509 K++ L+ +G+ DV + + + K E V ++ ++ Sbjct: 463 -KSNYLFVAVGQVGGACRDVQ------------QTVLQVGQFSKREKLVEILRNIGDERT 509 Query: 510 IIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFL 569 ++F TK D + + Q+ + S +HGDR+ ER+Q L F+ G L Sbjct: 510 MVFVETKKKADFIATFLCQE---------KISTTSIHGDREQREREQALGDFRFGKCPVL 560 Query: 570 ICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624 + T VAARG+DI V +VIN LP YVHRIGR GR G AIS E + Sbjct: 561 VATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESD 615 Score = 46.2 bits (108), Expect = 1e-04 Identities = 21/58 (36%), Positives = 34/58 (58%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 F E + + + + + T +Q SIP+IL G D++ A+TGSGKT AF +P++ Sbjct: 256 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 313 >gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sapiens] Length = 619 Score = 120 bits (301), Expect = 5e-27 Identities = 89/357 (24%), Positives = 165/357 (46%), Gaps = 61/357 (17%) Query: 277 VTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVL 336 + + F P ALI+ P+RELA Q K+ + P+++ +L++GG+ QL L Sbjct: 262 IMRALFESKTPSALILTPTRELAIQIERQAKELMSGL--PRMKTVLLVGGLPLPPQLYRL 319 Query: 337 ENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTS 396 + V +++ TPGRL D++ + L V+ +V+DEAD +L G+ + + IP Sbjct: 320 QQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIP---- 375 Query: 397 DGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVP-DTVHHVVVPVN--PKTD 453 Q I+ SAT+ + +++L+ +++H P + + GE ++P V +++ V K Sbjct: 376 --NDCQTILVSATIPT-SIEQLASQLLHNPVRI-ITGEKNLPCANVRQIILWVEDPAKKK 431 Query: 454 RLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFC 513 +L+E L + V + + GA ++ SEA++ + G Sbjct: 432 KLFEILNDKKLFKPPVLVFVDCKLGA---DLLSEAVQKITG------------------- 469 Query: 514 RTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTD 573 + +H ++ ERK L+ +GD ++ T Sbjct: 470 --------------------------LKSISIHSEKSQIERKNILKGLLEGDYEVVVSTG 503 Query: 574 VAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHV 630 V RG+D+ V V+N +P YVH+IGRVGR + G AI+ + +++++ + Sbjct: 504 VLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560 Score = 47.0 bits (110), Expect = 6e-05 Identities = 24/53 (45%), Positives = 37/53 (69%), Gaps = 1/53 (1%) Query: 10 MPEIAQA-VEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 +PE+ +++ + +PT IQ + IP+ L G D+L +A+TGSGKT AF +PVI Sbjct: 210 LPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVI 262 >gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapiens] Length = 483 Score = 119 bits (297), Expect = 1e-26 Identities = 97/336 (28%), Positives = 151/336 (44%), Gaps = 67/336 (19%) Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347 +A+++ P+RELA Q Q K++ K+ + GG RD + L++ V +V+ TP Sbjct: 166 QAMVIVPTRELALQVSQICIQVSKHMGGAKV--MATTGGTNLRDDIMRLDDTVHVVIATP 223 Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407 GR+ DL+ G + V+ +VLDEAD LLSQ DF+ M + I + K Q+++ S Sbjct: 224 GRILDLIKKGVAKVDHVQMIVLDEADKLLSQ---DFVQIMEDIILTLP---KNRQILLYS 277 Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPD-TVHHVVVPVNPKT---DRLWERLGKSH 463 AT V+K + P ++L E ++ T ++ V K + L+ RL Sbjct: 278 ATF-PLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRL---- 332 Query: 464 IRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE 523 +++Q+IIFC + + L Sbjct: 333 -----------------------------------------QINQSIIFCNSSQRVELLA 351 Query: 524 QYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHG 583 + Q G +SC +H + R + F+ G R L+CTD+ RGIDI Sbjct: 352 KKISQLG---------YSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQA 402 Query: 584 VPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619 V VIN P + Y+HRIGR GR +GLAI+L+ Sbjct: 403 VNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLI 438 Score = 54.3 bits (129), Expect = 4e-07 Identities = 24/59 (40%), Positives = 38/59 (64%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 F + + E+ + EM W P+ IQ ESIP+ L G D+L A+ G+GK+GA+ IP+++ Sbjct: 98 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 156 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 115 bits (289), Expect = 1e-25 Identities = 94/344 (27%), Positives = 154/344 (44%), Gaps = 65/344 (18%) Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346 P A+I+ P+RELA Q K+F K + LR + + GG +Q++ L+ G +I+V T Sbjct: 446 PIAVIMTPTRELALQITKECKKFSKTLG---LRVVCVYGGTGISEQIAELKRGAEIIVCT 502 Query: 347 PGRLDDLVSTGK---LNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQV 403 PGR+ D+++ NL +V ++VLDEAD + G+ + R+ + V D Q Sbjct: 503 PGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRI---VDNVRPD---RQT 556 Query: 404 IVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHH--VVVPVNPKTDRLWERLGK 461 ++ SAT ++ L+ +I+ P V + G V V +V+ K +L E LG Sbjct: 557 VMFSATFPR-AMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLG- 614 Query: 462 SHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDN 521 + E S I + K E+A +K Sbjct: 615 ------------------HYQESGSVIIFVDKQEHADGLLK------------------- 637 Query: 522 LEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI 581 D + C+ LHG ++R + FK G + L+ T VAARG+D+ Sbjct: 638 ------------DLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDV 685 Query: 582 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEK 625 + V+N + P+ ++YVHR GR GRA G A + + ++ + Sbjct: 686 KHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQAR 729 Score = 47.8 bits (112), Expect = 4e-05 Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 4/76 (5%) Query: 6 EMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVY 65 + G+ +I ++++ + PT IQ ++IP I+ G D++ A+TGSGKT AF +P ++ Sbjct: 376 QCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLP----MF 431 Query: 66 ETLKDQQEGKKGKTTI 81 + DQ+ ++G+ I Sbjct: 432 RHIMDQRSLEEGEGPI 447 >gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 [Homo sapiens] Length = 881 Score = 115 bits (289), Expect = 1e-25 Identities = 100/336 (29%), Positives = 155/336 (46%), Gaps = 57/336 (16%) Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347 +ALI+ P+RELA QTL K+ K+ L+ LI+GG DQ + L DI++ TP Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTG---LKTALILGGDRMEDQFAALHENPDIIIATP 224 Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407 GRL + L L V ++V DEAD L G+++ + + ++P Q ++ S Sbjct: 225 GRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGH------QTVLFS 278 Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTD 467 ATL V E + V++ ++ T +L E+L +T Sbjct: 279 ATLPKLLV------------------EFARAGLTEPVLIRLDVDT-KLNEQL-----KTS 314 Query: 468 DVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFI 527 +++T+ A+ + VR DQ ++F TK + L + Sbjct: 315 FFLVREDTKA----------AVLLHLLHNVVRP-----QDQTVVFVATKHHAEYLTELLT 359 Query: 528 QQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYV 587 Q + SC ++ P RK NL +F G LI TD+AARG+DI + V Sbjct: 360 TQ---------RVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNV 410 Query: 588 INVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEK 623 IN + P + + ++HR+GRV RA R G A SLVA ++ Sbjct: 411 INYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDE 446 Score = 50.8 bits (120), Expect = 4e-06 Identities = 23/59 (38%), Positives = 37/59 (62%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 F MG+ + + + + + +PT IQ ++IP+IL G DV+ A TGSGKT F +P+ + Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156 >gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1 [Homo sapiens] Length = 882 Score = 115 bits (289), Expect = 1e-25 Identities = 100/336 (29%), Positives = 155/336 (46%), Gaps = 57/336 (16%) Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347 +ALI+ P+RELA QTL K+ K+ L+ LI+GG DQ + L DI++ TP Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTG---LKTALILGGDRMEDQFAALHENPDIIIATP 224 Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407 GRL + L L V ++V DEAD L G+++ + + ++P Q ++ S Sbjct: 225 GRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGH------QTVLFS 278 Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTD 467 ATL V E + V++ ++ T +L E+L +T Sbjct: 279 ATLPKLLV------------------EFARAGLTEPVLIRLDVDT-KLNEQL-----KTS 314 Query: 468 DVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFI 527 +++T+ A+ + VR DQ ++F TK + L + Sbjct: 315 FFLVREDTKA----------AVLLHLLHNVVRP-----QDQTVVFVATKHHAEYLTELLT 359 Query: 528 QQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYV 587 Q + SC ++ P RK NL +F G LI TD+AARG+DI + V Sbjct: 360 TQ---------RVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNV 410 Query: 588 INVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEK 623 IN + P + + ++HR+GRV RA R G A SLVA ++ Sbjct: 411 INYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDE 446 Score = 50.8 bits (120), Expect = 4e-06 Identities = 23/59 (38%), Positives = 37/59 (62%) Query: 4 FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62 F MG+ + + + + + +PT IQ ++IP+IL G DV+ A TGSGKT F +P+ + Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156 >gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapiens] Length = 631 Score = 114 bits (284), Expect = 4e-25 Identities = 91/345 (26%), Positives = 151/345 (43%), Gaps = 64/345 (18%) Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344 N P L++ P+RELA L+ + KY L+ + I GG Q+ + GVDI++ Sbjct: 295 NGPGMLVLTPTRELA---LHVEAECSKY-SYKGLKSICIYGGRNRNGQIEDISKGVDIII 350 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 TPGRL+DL +NL + +LV+DEAD +L + I ++ Sbjct: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKI----------------- 393 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 DV+ + +M TW PDTV +L S++ Sbjct: 394 -------LLDVRPDRQTVMTSATW---------PDTVR---------------QLALSYL 422 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKM---DQAIIFCRTKIDCDN 521 + + N A + + + K + A+ M D+ I+F K D+ Sbjct: 423 KDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADD 482 Query: 522 LEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI 581 L F QG S LHG+ + ++++ +E FK G+++ LI TD+ +RG+D+ Sbjct: 483 LSSDFNIQG---------ISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDL 533 Query: 582 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKV 626 + V +V N P YVHR+G +GR + G +++L+ K+ Sbjct: 534 NDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578 Score = 41.6 bits (96), Expect = 0.003 Identities = 17/49 (34%), Positives = 36/49 (73%) Query: 11 PEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIP 59 P++ +++ + + PT IQ+++ P+IL G D+++ A+TG+GKT ++ +P Sbjct: 231 PDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMP 279 >gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [Homo sapiens] Length = 370 Score = 113 bits (283), Expect = 6e-25 Identities = 112/434 (25%), Positives = 187/434 (43%), Gaps = 106/434 (24%) Query: 258 LSKAPDGYIVKSQHSGN-------AQVTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFK 310 L++ P I +SQ A ++Q + P+ L + P+ ELA QT I+Q Sbjct: 18 LAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMG 77 Query: 311 KYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGK-LNLSQVRFLVL 369 K+ P+L+ + G + E IV+GTPG + D S K ++ +++ VL Sbjct: 78 KFY--PELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVL 132 Query: 370 DEADGLLS-QGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTW 428 DEAD +++ QG+ D R+ +P + Q+++ SAT V K ++K++ P Sbjct: 133 DEADVMIATQGHQDQSIRIQRMLP------RNCQMLLFSATFED-SVWKFAQKVVPDPNV 185 Query: 429 VDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEA 488 + LK E+ DT+ V + + ++ +A Sbjct: 186 IKLKREEETLDTIKQYYVLCSSRDEKF-------------------------------QA 214 Query: 489 IKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGD 548 + L G + QA+IFC T+ L K+GHQ + L G+ Sbjct: 215 LCNLYGAITIA--------QAMIFCHTRKTASWLAAEL-------SKEGHQVAL--LSGE 257 Query: 549 RKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEK------QNYVHR 602 +R +ERF++G + L+ T+V ARGID+ V VIN LP +K + Y+HR Sbjct: 258 MMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHR 317 Query: 603 IGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLSEI 662 IGR GR + GLA+++V ++ + M +L+ I Sbjct: 318 IGRTGRFGKRGLAVNMVDSK-------------------------------HSMNILNRI 346 Query: 663 EEHLNCTISQVEPD 676 +EH N I +++ D Sbjct: 347 QEHFNKKIERLDTD 360 >gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo sapiens] Length = 479 Score = 113 bits (283), Expect = 6e-25 Identities = 112/434 (25%), Positives = 187/434 (43%), Gaps = 106/434 (24%) Query: 258 LSKAPDGYIVKSQHSGN-------AQVTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFK 310 L++ P I +SQ A ++Q + P+ L + P+ ELA QT I+Q Sbjct: 127 LAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMG 186 Query: 311 KYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGK-LNLSQVRFLVL 369 K+ P+L+ + G + E IV+GTPG + D S K ++ +++ VL Sbjct: 187 KFY--PELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVL 241 Query: 370 DEADGLLS-QGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTW 428 DEAD +++ QG+ D R+ +P + Q+++ SAT V K ++K++ P Sbjct: 242 DEADVMIATQGHQDQSIRIQRMLP------RNCQMLLFSATFED-SVWKFAQKVVPDPNV 294 Query: 429 VDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEA 488 + LK E+ DT+ V + + ++ +A Sbjct: 295 IKLKREEETLDTIKQYYVLCSSRDEKF-------------------------------QA 323 Query: 489 IKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGD 548 + L G + QA+IFC T+ L K+GHQ + L G+ Sbjct: 324 LCNLYGAITIA--------QAMIFCHTRKTASWLAAEL-------SKEGHQVAL--LSGE 366 Query: 549 RKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEK------QNYVHR 602 +R +ERF++G + L+ T+V ARGID+ V VIN LP +K + Y+HR Sbjct: 367 MMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHR 426 Query: 603 IGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLSEI 662 IGR GR + GLA+++V ++ + M +L+ I Sbjct: 427 IGRTGRFGKRGLAVNMVDSK-------------------------------HSMNILNRI 455 Query: 663 EEHLNCTISQVEPD 676 +EH N I +++ D Sbjct: 456 QEHFNKKIERLDTD 469 Score = 38.1 bits (87), Expect = 0.030 Identities = 19/64 (29%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Query: 3 AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILG--GGDVLMAAETGSGKTGAFSIPV 60 +F E+ + P++ Q V M + P+ IQ ++PL+L +++ +++G+GKT AF + + Sbjct: 93 SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 152 Query: 61 IQIV 64 + V Sbjct: 153 LSQV 156 >gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 112 bits (281), Expect = 9e-25 Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 57/335 (17%) Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344 + P A+IV P+REL +Q K+F K + LR + + GG + +Q L+ G +IVV Sbjct: 325 DGPIAVIVCPTRELCQQIHAECKRFGKAYN---LRSVAVYGGGSMWEQAKALQEGAEIVV 381 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 TPGRL D V NL +V +LV DEAD + G+ + + + + Q + Sbjct: 382 CTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR------QTL 435 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 + SAT ++KL+ I+ P V V + N ++ E L Sbjct: 436 LFSATFRK-KIEKLARDILIDPIRV-----------VQGDIGEANEDVTQIVEILH---- 479 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524 + P W+ + R ++ ++F K + + L Sbjct: 480 ---------------SGPSKWNWLTR--------RLVEFTSSGSVLLFVTKKANAEELAN 516 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 Q+G H LHGD ER + + FKK D+ L+ TDVAARG+DI + Sbjct: 517 NLKQEG-------HNLGL--LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSI 567 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619 VIN + + + HRIGR GRA G+A +L+ Sbjct: 568 KTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602 Score = 47.8 bits (112), Expect = 4e-05 Identities = 20/60 (33%), Positives = 37/60 (61%) Query: 2 AAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 ++F+ G ++ + + ++ PT IQ + +P+ L G D++ A+TGSGKT AF P++ Sbjct: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312 >gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 112 bits (281), Expect = 9e-25 Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 57/335 (17%) Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344 + P A+IV P+REL +Q K+F K + LR + + GG + +Q L+ G +IVV Sbjct: 325 DGPIAVIVCPTRELCQQIHAECKRFGKAYN---LRSVAVYGGGSMWEQAKALQEGAEIVV 381 Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404 TPGRL D V NL +V +LV DEAD + G+ + + + + Q + Sbjct: 382 CTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR------QTL 435 Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464 + SAT ++KL+ I+ P V V + N ++ E L Sbjct: 436 LFSATFRK-KIEKLARDILIDPIRV-----------VQGDIGEANEDVTQIVEILH---- 479 Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524 + P W+ + R ++ ++F K + + L Sbjct: 480 ---------------SGPSKWNWLTR--------RLVEFTSSGSVLLFVTKKANAEELAN 516 Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584 Q+G H LHGD ER + + FKK D+ L+ TDVAARG+DI + Sbjct: 517 NLKQEG-------HNLGL--LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSI 567 Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619 VIN + + + HRIGR GRA G+A +L+ Sbjct: 568 KTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602 Score = 47.8 bits (112), Expect = 4e-05 Identities = 20/60 (33%), Positives = 37/60 (61%) Query: 2 AAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61 ++F+ G ++ + + ++ PT IQ + +P+ L G D++ A+TGSGKT AF P++ Sbjct: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312 >gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [Homo sapiens] Length = 448 Score = 112 bits (280), Expect = 1e-24 Identities = 114/440 (25%), Positives = 191/440 (43%), Gaps = 104/440 (23%) Query: 245 EEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAEQTLN 304 EE + P +A S++ G K+ A ++Q + P+ L + P+ ELA QT Sbjct: 95 EELRLP--QNLIAQSQSGTG---KTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 149 Query: 305 NIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGK-LNLSQ 363 I+Q K+ P+L+ + G + E IV+GTPG + D S K ++ + Sbjct: 150 VIEQMGKFY--PELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKK 204 Query: 364 VRFLVLDEADGLLS-QGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKI 422 ++ VLDEAD +++ QG+ D R+ +P + Q+++ SAT V K ++K+ Sbjct: 205 IKVFVLDEADVMIATQGHQDQSIRIQRMLP------RNCQMLLFSATFED-SVWKFAQKV 257 Query: 423 MHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSP 482 + P + LK E+ DT+ V + + ++ Sbjct: 258 VPDPNVIKLKREEETLDTIKQYYVLCSSRDEKF--------------------------- 290 Query: 483 EMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSC 542 +A+ L G + QA+IFC T+ L K+GHQ + Sbjct: 291 ----QALCNLYGAITIA--------QAMIFCHTRKTASWLAAEL-------SKEGHQVAL 331 Query: 543 VCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEK------ 596 L G+ +R +ERF++G + L+ T+V ARGID+ V VIN LP +K Sbjct: 332 --LSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 389 Query: 597 QNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEM 656 + Y+HRIGR GR + GLA+++V ++ + M Sbjct: 390 ETYLHRIGRTGRFGKRGLAVNMVDSK-------------------------------HSM 418 Query: 657 QLLSEIEEHLNCTISQVEPD 676 +L+ I+EH N I +++ D Sbjct: 419 NILNRIQEHFNKKIERLDTD 438 >gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 isoform d [Homo sapiens] Length = 756 Score = 112 bits (279), Expect = 2e-24 Identities = 59/165 (35%), Positives = 93/165 (56%), Gaps = 23/165 (13%) Query: 97 DRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCH-------------DQG 143 DR S + + +G W G RA+ G+ +G+ +E+ + D Sbjct: 127 DRSSGYPLTIEGFAYL------WSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPH 180 Query: 144 LCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFDNYGEEFTMHDTIGCYLDIDKGH- 202 + R+GWS S LG + F +G+GGTGKKS N +F+NYG++F +D IGC+ D + G+ Sbjct: 181 VVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGND 240 Query: 203 --VKFSKNGKDLGLAFEIPPH-MKNQALFPACVLKNAELKFNFGE 244 + F+KNGK +G+AF I + QAL+P ++KN ++FNFG+ Sbjct: 241 VELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQ 285 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.137 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,248,578 Number of Sequences: 37866 Number of extensions: 1352755 Number of successful extensions: 2829 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 2545 Number of HSP's gapped (non-prelim): 211 length of query: 740 length of database: 18,247,518 effective HSP length: 110 effective length of query: 630 effective length of database: 14,082,258 effective search space: 8871822540 effective search space used: 8871822540 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.