Guide to the Human Genome
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Search of human proteins with 4826686

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo
sapiens]
         (740 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]   1519   0.0  
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   137   5e-32
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   137   5e-32
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   137   5e-32
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   136   8e-32
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      136   8e-32
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         134   3e-31
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          134   3e-31
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  132   2e-30
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    131   2e-30
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   128   2e-29
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   127   4e-29
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   127   5e-29
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   126   6e-29
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   124   2e-28
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   123   7e-28
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   123   7e-28
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   123   7e-28
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   120   5e-27
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   119   1e-26
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   115   1e-25
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   115   1e-25
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   115   1e-25
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   114   4e-25
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [...   113   6e-25
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H...   113   6e-25
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            112   9e-25
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            112   9e-25
gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [...   112   1e-24
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso...   112   2e-24

>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
          Length = 740

 Score = 1519 bits (3933), Expect = 0.0
 Identities = 740/740 (100%), Positives = 740/740 (100%)

Query: 1   MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV 60
           MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV
Sbjct: 1   MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV 60

Query: 61  IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH 120
           IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH
Sbjct: 61  IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH 120

Query: 121 GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD 180
           GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD
Sbjct: 121 GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD 180

Query: 181 NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF 240
           NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF
Sbjct: 181 NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF 240

Query: 241 NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE 300
           NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE
Sbjct: 241 NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE 300

Query: 301 QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN 360
           QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN
Sbjct: 301 QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN 360

Query: 361 LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE 420
           LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE
Sbjct: 361 LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE 420

Query: 421 KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN 480
           KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN
Sbjct: 421 KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN 480

Query: 481 SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF 540
           SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF
Sbjct: 481 SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF 540

Query: 541 SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV 600
           SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV
Sbjct: 541 SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV 600

Query: 601 HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS 660
           HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS
Sbjct: 601 HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS 660

Query: 661 EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK 720
           EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK
Sbjct: 661 EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK 720

Query: 721 EAQTSFLHLGYLPNQLFRTF 740
           EAQTSFLHLGYLPNQLFRTF
Sbjct: 721 EAQTSFLHLGYLPNQLFRTF 740


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  137 bits (344), Expect = 5e-32
 Identities = 96/333 (28%), Positives = 156/333 (46%), Gaps = 58/333 (17%)

Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346
           P +L++ P+RELA Q     ++F       ++R  ++ GG     Q+  LE G  ++V T
Sbjct: 267 PISLVLAPTRELAVQIYEEARKFSY---RSRVRPCVVYGGADIGQQIRDLERGCHLLVAT 323

Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQ-VIV 405
           PGRL D++  GK+ L   ++LVLDEAD +L  G+   I R+   + Q T   K ++  ++
Sbjct: 324 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI---VEQDTMPPKGVRHTMM 380

Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465
            SAT               FP  + +   D + + +   V  V   ++ + +++      
Sbjct: 381 FSAT---------------FPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKV------ 419

Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQ-AIIFCRTKIDCDNLEQ 524
                             +W E     K  + +  +     D   ++F  TK   D+LE 
Sbjct: 420 ------------------VWVEESD--KRSFLLDLLNATGKDSLTLVFVETKKGADSLED 459

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
           +   +G         ++C  +HGDR   +R++ L +F+ G    L+ T VAARG+DI  V
Sbjct: 460 FLYHEG---------YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNV 510

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAIS 617
            +VIN  LP + + YVHRIGR GR   +GLA S
Sbjct: 511 KHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 543



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 6/82 (7%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           +FS++ +   I   +E   +  PT +Q  +IP+I    D++  A+TGSGKT AF +P++ 
Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240

Query: 63  IVY-----ETLKDQQE-GKKGK 78
            +Y     E L+  +E G+ G+
Sbjct: 241 QIYSDGPGEALRAMKENGRYGR 262


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  137 bits (344), Expect = 5e-32
 Identities = 96/333 (28%), Positives = 157/333 (47%), Gaps = 58/333 (17%)

Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346
           P +L++ P+RELA Q     ++F       ++R  ++ GG     Q+  LE G  ++V T
Sbjct: 265 PISLVLAPTRELAVQIYEEARKFSY---RSRVRPCVVYGGADIGQQIRDLERGCHLLVAT 321

Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQ-VIV 405
           PGRL D++  GK+ L   ++LVLDEAD +L  G+   I R+   + Q T   K ++  ++
Sbjct: 322 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI---VEQDTMPPKGVRHTMM 378

Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465
            SAT               FP  + +   D + + +   V  V   ++ + +++      
Sbjct: 379 FSAT---------------FPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKV------ 417

Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQ-AIIFCRTKIDCDNLEQ 524
                             +W E +   K  + +  +     D   ++F  TK   D+LE 
Sbjct: 418 ------------------VWVEDLD--KRSFLLDILGATGSDSLTLVFVETKKGADSLED 457

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
           +   +G         ++C  +HGDR   +R++ L +F+ G    L+ T VAARG+DI  V
Sbjct: 458 FLYHEG---------YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNV 508

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAIS 617
            +VIN  LP + + YVHRIGR GR   +GLA S
Sbjct: 509 RHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 541



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 6/81 (7%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63
           FS++ +   I   +E   +  PT +Q  +IP+I G  D++  A+TGSGKT AF +P++  
Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239

Query: 64  VY-----ETLKDQQE-GKKGK 78
           +Y     E LK  +E G+ G+
Sbjct: 240 IYTDGPGEALKAVKENGRYGR 260


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  137 bits (344), Expect = 5e-32
 Identities = 96/333 (28%), Positives = 157/333 (47%), Gaps = 58/333 (17%)

Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346
           P +L++ P+RELA Q     ++F       ++R  ++ GG     Q+  LE G  ++V T
Sbjct: 265 PISLVLAPTRELAVQIYEEARKFSY---RSRVRPCVVYGGADIGQQIRDLERGCHLLVAT 321

Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQ-VIV 405
           PGRL D++  GK+ L   ++LVLDEAD +L  G+   I R+   + Q T   K ++  ++
Sbjct: 322 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI---VEQDTMPPKGVRHTMM 378

Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465
            SAT               FP  + +   D + + +   V  V   ++ + +++      
Sbjct: 379 FSAT---------------FPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKV------ 417

Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQ-AIIFCRTKIDCDNLEQ 524
                             +W E +   K  + +  +     D   ++F  TK   D+LE 
Sbjct: 418 ------------------VWVEDLD--KRSFLLDILGATGSDSLTLVFVETKKGADSLED 457

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
           +   +G         ++C  +HGDR   +R++ L +F+ G    L+ T VAARG+DI  V
Sbjct: 458 FLYHEG---------YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNV 508

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAIS 617
            +VIN  LP + + YVHRIGR GR   +GLA S
Sbjct: 509 RHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 541



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 6/81 (7%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63
           FS++ +   I   +E   +  PT +Q  +IP+I G  D++  A+TGSGKT AF +P++  
Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239

Query: 64  VY-----ETLKDQQE-GKKGK 78
           +Y     E LK  +E G+ G+
Sbjct: 240 IYTDGPGEALKAVKENGRYGR 260


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  136 bits (342), Expect = 8e-32
 Identities = 105/353 (29%), Positives = 161/353 (45%), Gaps = 80/353 (22%)

Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344
           N P  L++ P+RELA Q      ++        LR + + GG    +Q+  L+ GVDI++
Sbjct: 315 NRPGMLVLTPTRELALQVEGECCKYSY----KGLRSVCVYGGGNRDEQIEELKKGVDIII 370

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
            TPGRL+DL  +  +NL  + +LVLDEAD +L  G+           PQ+      ++++
Sbjct: 371 ATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFE----------PQI------MKIL 414

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
           +        DV+   + +M   TW         P +VH               RL +S++
Sbjct: 415 L--------DVRPDRQTVMTSATW---------PHSVH---------------RLAQSYL 442

Query: 465 R--------TDDVHAKDNTRPG---ANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFC 513
           +        T D+ A  + +         E WS     L+   +         D+ I+F 
Sbjct: 443 KEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSST--------DKVIVFV 494

Query: 514 RTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTD 573
             K   D+L    I             S   LHGDR+  +R++ LE FK G VR LI TD
Sbjct: 495 SRKAVADHLSSDLILGN---------ISVESLHGDREQRDREKALENFKTGKVRILIATD 545

Query: 574 VAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKV 626
           +A+RG+D+H V +V N   P   + YVHRIGR GRA R G++I+ +     +V
Sbjct: 546 LASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRV 598



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 20/64 (31%), Positives = 42/64 (65%), Gaps = 2/64 (3%)

Query: 11  PEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIP--VIQIVYETL 68
           PE+ + +++  +  PT IQ+++ P++L G D++  A+TG+GKT  + +P  +  ++  +L
Sbjct: 251 PEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSL 310

Query: 69  KDQQ 72
           K Q+
Sbjct: 311 KGQR 314


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  136 bits (342), Expect = 8e-32
 Identities = 96/333 (28%), Positives = 161/333 (48%), Gaps = 56/333 (16%)

Query: 286 APKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVG 345
           +PK L++ P+RELA Q   + K   +     KL      GG + + Q++ + NG+DI+VG
Sbjct: 211 SPKVLVLAPTRELANQVAKDFKDITR-----KLSVACFYGGTSYQSQINHIRNGIDILVG 265

Query: 346 TPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIV 405
           TPGR+ D + +G+L+LS++R +VLDE D +L  G+++ +  + ++  +  S+    Q ++
Sbjct: 266 TPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNP-QTLL 324

Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGE--DSVPDTVHHVVVPVNPKTDRLWERLGKSH 463
            SAT   +  K   + +      VDL G+       TV H+ +  +      W       
Sbjct: 325 FSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCH------W------- 371

Query: 464 IRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE 523
                          +  P +  + +++  G             +AIIFC TK +   + 
Sbjct: 372 ---------------SQRPAVIGDVLQVYSGSEG----------RAIIFCETKKNVTEMA 406

Query: 524 QYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHG 583
                    P  K    +  CLHGD    +R+  L+ F++G  + L+ T+VAARG+DI  
Sbjct: 407 M-------NPHIKQ---NAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPE 456

Query: 584 VPYVINVTLPDEKQNYVHRIGRVGRAERMGLAI 616
           V  VI  + P + ++Y+HR GR GRA R G+ I
Sbjct: 457 VDLVIQSSPPQDVESYIHRSGRTGRAGRTGICI 489



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           AFS   +  E  + ++         IQ ++   +  G D++  A TG+GKT +F+IP+I+
Sbjct: 138 AFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIE 197

Query: 63  IV---YETLKDQQEGK 75
            +    ET+K  +  K
Sbjct: 198 RLQRNQETIKKSRSPK 213


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  134 bits (337), Expect = 3e-31
 Identities = 97/331 (29%), Positives = 157/331 (47%), Gaps = 55/331 (16%)

Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344
           + P  L++ P+RELA+Q       + K     +L+   I GG     Q+  LE GV+I +
Sbjct: 243 DGPICLVLAPTRELAQQVQQVADDYGKC---SRLKSTCIYGGAPKGPQIRDLERGVEICI 299

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
            TPGRL D + +GK NL +  +LVLDEAD +L  G+   I ++   + Q+  D    Q +
Sbjct: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKI---VDQIRPDR---QTL 353

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
           + SAT    +V++L+E  +   T +++    ++  + +H ++ +                
Sbjct: 354 MWSATWPK-EVRQLAEDFLRDYTQINV---GNLELSANHNILQI---------------- 393

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524
                             ++  E+ K  K    +  I   K ++ IIF  TK  CD+L +
Sbjct: 394 -----------------VDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTR 436

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
              + G         +  +C+HGD+   ER   L  F+ G    LI TDVA+RG+D+  V
Sbjct: 437 RMRRDG---------WPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDV 487

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLA 615
            +VIN   P+  ++YVHRIGR  R+   G A
Sbjct: 488 KFVINYDYPNSSEDYVHRIGRTARSTNKGTA 518



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 21/59 (35%), Positives = 31/59 (52%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           AF        +   + +  +  PT IQ +  PL L G D++  A+TGSGKT A+ +P I
Sbjct: 172 AFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  134 bits (337), Expect = 3e-31
 Identities = 97/331 (29%), Positives = 157/331 (47%), Gaps = 55/331 (16%)

Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344
           + P  L++ P+RELA+Q       + K     +L+   I GG     Q+  LE GV+I +
Sbjct: 243 DGPICLVLAPTRELAQQVQQVADDYGKC---SRLKSTCIYGGAPKGPQIRDLERGVEICI 299

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
            TPGRL D + +GK NL +  +LVLDEAD +L  G+   I ++   + Q+  D    Q +
Sbjct: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKI---VDQIRPDR---QTL 353

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
           + SAT    +V++L+E  +   T +++    ++  + +H ++ +                
Sbjct: 354 MWSATWPK-EVRQLAEDFLRDYTQINV---GNLELSANHNILQI---------------- 393

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524
                             ++  E+ K  K    +  I   K ++ IIF  TK  CD+L +
Sbjct: 394 -----------------VDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTR 436

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
              + G         +  +C+HGD+   ER   L  F+ G    LI TDVA+RG+D+  V
Sbjct: 437 RMRRDG---------WPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDV 487

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLA 615
            +VIN   P+  ++YVHRIGR  R+   G A
Sbjct: 488 KFVINYDYPNSSEDYVHRIGRTARSTNKGTA 518



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 21/59 (35%), Positives = 31/59 (52%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           AF        +   + +  +  PT IQ +  PL L G D++  A+TGSGKT A+ +P I
Sbjct: 172 AFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  132 bits (331), Expect = 2e-30
 Identities = 101/348 (29%), Positives = 169/348 (48%), Gaps = 64/348 (18%)

Query: 279 QTKFLP----NAPKALIVEPSRELAEQTLNNIKQFKKYID---NPKLRELLIIGGVAARD 331
           Q K LP      P  LI+ PSRELA QT   ++ + + +    +P LR  L IGG++ ++
Sbjct: 246 QEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKE 305

Query: 332 QLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQI 391
           Q+  + +GV ++V TPGRL DL+    ++L   R+L LDEAD ++  G+   I  + +  
Sbjct: 306 QMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYF 365

Query: 392 PQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPK 451
                 G+R Q ++ SAT+         +KI +F     +K     P T++         
Sbjct: 366 K-----GQR-QTLLFSATM--------PKKIQNFAKSALVK-----PVTIN--------- 397

Query: 452 TDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAII 511
                  +G++   + DV             E   E  K++   Y +  +++      +I
Sbjct: 398 -------VGRAGAASLDV---------IQEVEYVKEEAKMV---YLLECLQKTP-PPVLI 437

Query: 512 FCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLIC 571
           F   K D D + +Y + +G            V +HG +   ER + +E F++G    L+ 
Sbjct: 438 FAEKKADVDAIHEYLLLKG---------VEAVAIHGGKDQEERTKAIEAFREGKKDVLVA 488

Query: 572 TDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619
           TDVA++G+D   + +VIN  +P+E +NYVHRIGR GR+   G+A + +
Sbjct: 489 TDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFI 536



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           +F EM     I + +++     PT IQ + IP IL G D++  A TGSGKT  F++PVI 
Sbjct: 182 SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIM 241

Query: 63  IVYETLK----DQQEGKKG 77
              E  K     ++EG  G
Sbjct: 242 FCLEQEKRLPFSKREGPYG 260


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  131 bits (330), Expect = 2e-30
 Identities = 98/334 (29%), Positives = 153/334 (45%), Gaps = 61/334 (18%)

Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344
           + P  L++ P+RELA+Q      ++ +     +L+   I GG     Q+  LE GV+I +
Sbjct: 166 DGPICLVLAPTRELAQQVQQVAAEYCRAC---RLKSTCIYGGAPKGPQIRDLERGVEICI 222

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
            TPGRL D +  GK NL +  +LVLDEAD +L  G+   I ++   + Q+  D    Q +
Sbjct: 223 ATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKI---VDQIRPDR---QTL 276

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
           + SAT               +P  V    ED + D +H  +  +          L  +H 
Sbjct: 277 MWSAT---------------WPKEVRQLAEDFLKDYIHINIGALE---------LSANH- 311

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKE---HKMDQAIIFCRTKIDCDN 521
                          N  ++      + K E  +R ++E    K ++ I+F  TK  CD 
Sbjct: 312 ---------------NILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDE 356

Query: 522 LEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI 581
           L +   + G         +  + +HGD+   ER   L  FK G    LI TDVA+RG+D+
Sbjct: 357 LTRKMRRDG---------WPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDV 407

Query: 582 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLA 615
             V +VIN   P+  ++Y+HRIGR  R+ + G A
Sbjct: 408 EDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTA 441



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIP-VIQ 62
           F E      +   +   ++  PT IQA+  P+ L G D++  A+TGSGKT ++ +P ++ 
Sbjct: 96  FYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVH 155

Query: 63  IVYETLKDQQEG 74
           I ++   ++ +G
Sbjct: 156 INHQPFLERGDG 167


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  128 bits (322), Expect = 2e-29
 Identities = 96/339 (28%), Positives = 155/339 (45%), Gaps = 52/339 (15%)

Query: 286 APKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVG 345
           AP+ L++ P+RELA Q   +     K     KL      GG     Q   + NG+DI+VG
Sbjct: 260 APQVLVLAPTRELANQVSKDFSDITK-----KLSVACFYGGTPYGGQFERMRNGIDILVG 314

Query: 346 TPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIV 405
           TPGR+ D +  GKL+L++++ +VLDE D +L  G++D +  + +   +  S+    Q ++
Sbjct: 315 TPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNP-QTLL 373

Query: 406 CSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIR 465
            SAT                P WV    +  +  T   V        D + ++  K+ I 
Sbjct: 374 FSATC---------------PHWVFNVAKKYMKSTYEQV--------DLIGKKTQKTAIT 410

Query: 466 TDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQY 525
            + +  K +          W++   ++     +R    H+  + IIFC TK +   L Q 
Sbjct: 411 VEHLAIKCH----------WTQRAAVIGD--VIRVYSGHQ-GRTIIFCETKKEAQELSQ- 456

Query: 526 FIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVP 585
                        +     LHGD    +R+  L+ F+ G    L+ T+VAARG+DI  V 
Sbjct: 457 ---------NSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVD 507

Query: 586 YVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624
            VI  + P + ++Y+HR GR GRA R G+ I     ++E
Sbjct: 508 LVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEE 546



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 22/73 (30%), Positives = 42/73 (57%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           AFS   +  E  + ++         IQA++   +  G D++  A TG+GKT +F+IP+I+
Sbjct: 187 AFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIE 246

Query: 63  IVYETLKDQQEGK 75
            ++  L+D++ G+
Sbjct: 247 KLHGELQDRKRGR 259


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  127 bits (319), Expect = 4e-29
 Identities = 107/359 (29%), Positives = 166/359 (46%), Gaps = 64/359 (17%)

Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLE-NGVDIVVGT 346
           +AL++ P+RELA+Q    I     Y+          IGG   R+++  L+     IVVGT
Sbjct: 103 QALVLAPTRELAQQIQKVILALGDYMGATCHA---CIGGTNVRNEMQKLQAEAPHIVVGT 159

Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVC 406
           PGR+ D+++   L+   ++  VLDEAD +LS+G+ D I  +  ++         +QV++ 
Sbjct: 160 PGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKL------NTSIQVVLL 213

Query: 407 SATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRT 466
           SAT+ + DV ++++K M  P  + +K E+   + +    + V        ER        
Sbjct: 214 SATMPT-DVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINV--------ER-------- 256

Query: 467 DDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYF 526
                           E W   +  L   Y    I      QA+IF  T+   D L +  
Sbjct: 257 ----------------EEWK--LDTLCDLYETLTIT-----QAVIFLNTRRKVDWLTEKM 293

Query: 527 IQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPY 586
                        F+   LHGD    ER   +  F+ G  R LI TD+ ARGID+  V  
Sbjct: 294 ---------HARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSL 344

Query: 587 VINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKE 645
           VIN  LP  ++NY+HRIGR GR  R G+AI+ V  E +++   +     +  YNT ++E
Sbjct: 345 VINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI-----ETFYNTTVEE 398



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 19/69 (27%), Positives = 37/69 (53%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63
           F +M +   + + +    +  P+ IQ  +I   + G DV+  A++G+GKT  F+I ++Q 
Sbjct: 35  FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94

Query: 64  VYETLKDQQ 72
           +    K+ Q
Sbjct: 95  LEIEFKETQ 103


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  127 bits (318), Expect = 5e-29
 Identities = 107/361 (29%), Positives = 166/361 (45%), Gaps = 64/361 (17%)

Query: 286 APKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLE-NGVDIVV 344
           A +AL++ P+RELA+Q    +     Y+          IGG   R ++  L+     I+V
Sbjct: 100 ATQALVLAPTRELAQQIQKVVMALGDYMGASCHA---CIGGTNVRAEVQKLQMEAPHIIV 156

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
           GTPGR+ D+++   L+   ++  VLDEAD +LS+G+ D I  +  ++   T      QV+
Sbjct: 157 GTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT------QVV 210

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
           + SAT+ S DV ++++K M  P  + +K E+   + +    + V        ER      
Sbjct: 211 LLSATMPS-DVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV--------ER------ 255

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524
                             E W   +  L   Y    I      QA+IF  T+   D L +
Sbjct: 256 ------------------EEWK--LDTLCDLYETLTIT-----QAVIFINTRRKVDWLTE 290

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
                          F+   +HGD    ER   +  F+ G  R LI TD+ ARGID+  V
Sbjct: 291 KM---------HARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQV 341

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLK 644
             VIN  LP  ++NY+HRIGR GR  R G+AI++V  E ++    +     +  YNT ++
Sbjct: 342 SLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI-----ETFYNTSIE 396

Query: 645 E 645
           E
Sbjct: 397 E 397



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 20/70 (28%), Positives = 38/70 (54%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           +F +M +   + + +    +  P+ IQ  +I   + G DV+  A++G+GKT  F+I ++Q
Sbjct: 33  SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92

Query: 63  IVYETLKDQQ 72
            +   LK  Q
Sbjct: 93  QIELDLKATQ 102


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  126 bits (317), Expect = 6e-29
 Identities = 99/339 (29%), Positives = 158/339 (46%), Gaps = 58/339 (17%)

Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347
           +ALI+ P+RELA Q    +     Y++   ++    IGG    + +  L+ G  +V GTP
Sbjct: 108 QALILAPTRELAVQIQKGLLALGDYMN---VQCHACIGGTNVGEDIRKLDYGQHVVAGTP 164

Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407
           GR+ D++    L    ++ LVLDEAD +L++G+ + I  ++  +P  T      QV++ S
Sbjct: 165 GRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT------QVVLIS 218

Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTD 467
           ATL   ++ +++ K M  P  + +K ++   + +    V V        ER         
Sbjct: 219 ATL-PHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAV--------ER--------- 260

Query: 468 DVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFI 527
                          E W      L   Y    I      QA+IFC TK   D L +   
Sbjct: 261 ---------------EEWK--FDTLCDLYDTLTIT-----QAVIFCNTKRKVDWLTEKMR 298

Query: 528 QQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYV 587
           +           F+   +HGD    ER+  ++ F+ G  R LI TDV ARG+D+  V  +
Sbjct: 299 EAN---------FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349

Query: 588 INVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKV 626
           IN  LP+ ++ Y+HRIGR GR  R G+AI+ V  +  ++
Sbjct: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRI 388



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 21/69 (30%), Positives = 40/69 (57%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQI 63
           F  MG+  ++ + +    +  P+ IQ  +I  I+ G DV+  +++G+GKT  FSI V+Q 
Sbjct: 40  FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99

Query: 64  VYETLKDQQ 72
           +   +++ Q
Sbjct: 100 LDIQVRETQ 108


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  124 bits (312), Expect = 2e-28
 Identities = 104/351 (29%), Positives = 158/351 (45%), Gaps = 47/351 (13%)

Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346
           P A+I+ P+RELA+Q      +F K +    +R + +IGG++  DQ   L  G +IV+ T
Sbjct: 469 PYAIILAPTRELAQQIEEETIKFGKPLG---IRTVAVIGGISREDQGFRLRMGCEIVIAT 525

Query: 347 PGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVC 406
           PGRL D++    L LS+  ++VLDEAD ++  G+   + ++   +P         +    
Sbjct: 526 PGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDP 585

Query: 407 SATLHSFDV--KKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
              L +F+    K  + +M   T         +P  V               ERL +S++
Sbjct: 586 EKMLANFESGKHKYRQTVMFTAT---------MPPAV---------------ERLARSYL 621

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVR----AIKEHKMDQAII-FCRTKIDC 519
           R   V    +    A  P    E    L  E   R    AI E   D  II F   K  C
Sbjct: 622 RRPAVVYIGS----AGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGC 677

Query: 520 DNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGI 579
           D L +   + G         ++   LHG +   +R+  L   K G    L+ TDVA RGI
Sbjct: 678 DVLAKSLEKMG---------YNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGI 728

Query: 580 DIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHV 630
           DI  V  V+N  +    ++Y+HRIGR GRA + G+AI+ +  E   V+Y +
Sbjct: 729 DIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYEL 779



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 22/59 (37%), Positives = 38/59 (64%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           ++ +  + P I + +++  +  PT IQ ++IP+ L   D++  AETGSGKT AF IP++
Sbjct: 392 SWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLL 450


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  123 bits (308), Expect = 7e-28
 Identities = 97/355 (27%), Positives = 163/355 (45%), Gaps = 55/355 (15%)

Query: 271 HSGNAQVTQTKFLP-NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAA 329
           H  +  +T ++F     P+ +IV P+REL  Q      + +K+     +R ++I GG   
Sbjct: 349 HMMHDGITASRFKELQEPECIIVAPTRELVNQIY---LEARKFSFGTCVRAVVIYGGTQL 405

Query: 330 RDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHN 389
              +  +  G +I+  TPGRL D++   K+ L Q+++LVLDEAD +L  G+   + ++ +
Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 465

Query: 390 QIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVN 449
             P + S  +R Q ++ SAT    ++++L+ + +                          
Sbjct: 466 -CPGMPSKEQR-QTLMFSATFPE-EIQRLAAEFL-------------------------- 496

Query: 450 PKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQA 509
            K++ L+  +G+      DV             +   +  +  K E  V  ++    ++ 
Sbjct: 497 -KSNYLFVAVGQVGGACRDVQ------------QTVLQVGQFSKREKLVEILRNIGDERT 543

Query: 510 IIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFL 569
           ++F  TK   D +  +  Q+         + S   +HGDR+  ER+Q L  F+ G    L
Sbjct: 544 MVFVETKKKADFIATFLCQE---------KISTTSIHGDREQREREQALGDFRFGKCPVL 594

Query: 570 ICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624
           + T VAARG+DI  V +VIN  LP     YVHRIGR GR    G AIS    E +
Sbjct: 595 VATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESD 649



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 21/58 (36%), Positives = 34/58 (58%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           F E  +   +   + +  +   T +Q  SIP+IL G D++  A+TGSGKT AF +P++
Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  123 bits (308), Expect = 7e-28
 Identities = 97/355 (27%), Positives = 163/355 (45%), Gaps = 55/355 (15%)

Query: 271 HSGNAQVTQTKFLP-NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAA 329
           H  +  +T ++F     P+ +IV P+REL  Q      + +K+     +R ++I GG   
Sbjct: 349 HMMHDGITASRFKELQEPECIIVAPTRELVNQIY---LEARKFSFGTCVRAVVIYGGTQL 405

Query: 330 RDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHN 389
              +  +  G +I+  TPGRL D++   K+ L Q+++LVLDEAD +L  G+   + ++ +
Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 465

Query: 390 QIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVN 449
             P + S  +R Q ++ SAT    ++++L+ + +                          
Sbjct: 466 -CPGMPSKEQR-QTLMFSATFPE-EIQRLAAEFL-------------------------- 496

Query: 450 PKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQA 509
            K++ L+  +G+      DV             +   +  +  K E  V  ++    ++ 
Sbjct: 497 -KSNYLFVAVGQVGGACRDVQ------------QTVLQVGQFSKREKLVEILRNIGDERT 543

Query: 510 IIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFL 569
           ++F  TK   D +  +  Q+         + S   +HGDR+  ER+Q L  F+ G    L
Sbjct: 544 MVFVETKKKADFIATFLCQE---------KISTTSIHGDREQREREQALGDFRFGKCPVL 594

Query: 570 ICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624
           + T VAARG+DI  V +VIN  LP     YVHRIGR GR    G AIS    E +
Sbjct: 595 VATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESD 649



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 21/58 (36%), Positives = 34/58 (58%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           F E  +   +   + +  +   T +Q  SIP+IL G D++  A+TGSGKT AF +P++
Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  123 bits (308), Expect = 7e-28
 Identities = 97/355 (27%), Positives = 163/355 (45%), Gaps = 55/355 (15%)

Query: 271 HSGNAQVTQTKFLP-NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAA 329
           H  +  +T ++F     P+ +IV P+REL  Q      + +K+     +R ++I GG   
Sbjct: 315 HMMHDGITASRFKELQEPECIIVAPTRELVNQIY---LEARKFSFGTCVRAVVIYGGTQL 371

Query: 330 RDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHN 389
              +  +  G +I+  TPGRL D++   K+ L Q+++LVLDEAD +L  G+   + ++ +
Sbjct: 372 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 431

Query: 390 QIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVN 449
             P + S  +R Q ++ SAT    ++++L+ + +                          
Sbjct: 432 -CPGMPSKEQR-QTLMFSATFPE-EIQRLAAEFL-------------------------- 462

Query: 450 PKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQA 509
            K++ L+  +G+      DV             +   +  +  K E  V  ++    ++ 
Sbjct: 463 -KSNYLFVAVGQVGGACRDVQ------------QTVLQVGQFSKREKLVEILRNIGDERT 509

Query: 510 IIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFL 569
           ++F  TK   D +  +  Q+         + S   +HGDR+  ER+Q L  F+ G    L
Sbjct: 510 MVFVETKKKADFIATFLCQE---------KISTTSIHGDREQREREQALGDFRFGKCPVL 560

Query: 570 ICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624
           + T VAARG+DI  V +VIN  LP     YVHRIGR GR    G AIS    E +
Sbjct: 561 VATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESD 615



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 21/58 (36%), Positives = 34/58 (58%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           F E  +   +   + +  +   T +Q  SIP+IL G D++  A+TGSGKT AF +P++
Sbjct: 256 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 313


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  120 bits (301), Expect = 5e-27
 Identities = 89/357 (24%), Positives = 165/357 (46%), Gaps = 61/357 (17%)

Query: 277 VTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVL 336
           + +  F    P ALI+ P+RELA Q     K+    +  P+++ +L++GG+    QL  L
Sbjct: 262 IMRALFESKTPSALILTPTRELAIQIERQAKELMSGL--PRMKTVLLVGGLPLPPQLYRL 319

Query: 337 ENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTS 396
           +  V +++ TPGRL D++    + L  V+ +V+DEAD +L  G+   +  +   IP    
Sbjct: 320 QQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIP---- 375

Query: 397 DGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVP-DTVHHVVVPVN--PKTD 453
                Q I+ SAT+ +  +++L+ +++H P  + + GE ++P   V  +++ V    K  
Sbjct: 376 --NDCQTILVSATIPT-SIEQLASQLLHNPVRI-ITGEKNLPCANVRQIILWVEDPAKKK 431

Query: 454 RLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFC 513
           +L+E L    +    V    + + GA   ++ SEA++ + G                   
Sbjct: 432 KLFEILNDKKLFKPPVLVFVDCKLGA---DLLSEAVQKITG------------------- 469

Query: 514 RTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTD 573
                                        + +H ++   ERK  L+   +GD   ++ T 
Sbjct: 470 --------------------------LKSISIHSEKSQIERKNILKGLLEGDYEVVVSTG 503

Query: 574 VAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHV 630
           V  RG+D+  V  V+N  +P     YVH+IGRVGR  + G AI+ +    +++++ +
Sbjct: 504 VLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 24/53 (45%), Positives = 37/53 (69%), Gaps = 1/53 (1%)

Query: 10  MPEIAQA-VEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           +PE+    +++  + +PT IQ + IP+ L G D+L +A+TGSGKT AF +PVI
Sbjct: 210 LPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVI 262


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  119 bits (297), Expect = 1e-26
 Identities = 97/336 (28%), Positives = 151/336 (44%), Gaps = 67/336 (19%)

Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347
           +A+++ P+RELA Q      Q  K++   K+  +   GG   RD +  L++ V +V+ TP
Sbjct: 166 QAMVIVPTRELALQVSQICIQVSKHMGGAKV--MATTGGTNLRDDIMRLDDTVHVVIATP 223

Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407
           GR+ DL+  G   +  V+ +VLDEAD LLSQ   DF+  M + I  +    K  Q+++ S
Sbjct: 224 GRILDLIKKGVAKVDHVQMIVLDEADKLLSQ---DFVQIMEDIILTLP---KNRQILLYS 277

Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPD-TVHHVVVPVNPKT---DRLWERLGKSH 463
           AT     V+K     +  P  ++L  E ++   T ++  V    K    + L+ RL    
Sbjct: 278 ATF-PLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRL---- 332

Query: 464 IRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE 523
                                                    +++Q+IIFC +    + L 
Sbjct: 333 -----------------------------------------QINQSIIFCNSSQRVELLA 351

Query: 524 QYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHG 583
           +   Q G         +SC  +H   +   R +    F+ G  R L+CTD+  RGIDI  
Sbjct: 352 KKISQLG---------YSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQA 402

Query: 584 VPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619
           V  VIN   P   + Y+HRIGR GR   +GLAI+L+
Sbjct: 403 VNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLI 438



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 24/59 (40%), Positives = 38/59 (64%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           F +  +  E+   + EM W  P+ IQ ESIP+ L G D+L  A+ G+GK+GA+ IP+++
Sbjct: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 156


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  115 bits (289), Expect = 1e-25
 Identities = 94/344 (27%), Positives = 154/344 (44%), Gaps = 65/344 (18%)

Query: 287 PKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGT 346
           P A+I+ P+RELA Q     K+F K +    LR + + GG    +Q++ L+ G +I+V T
Sbjct: 446 PIAVIMTPTRELALQITKECKKFSKTLG---LRVVCVYGGTGISEQIAELKRGAEIIVCT 502

Query: 347 PGRLDDLVSTGK---LNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQV 403
           PGR+ D+++       NL +V ++VLDEAD +   G+   + R+   +  V  D    Q 
Sbjct: 503 PGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRI---VDNVRPD---RQT 556

Query: 404 IVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHH--VVVPVNPKTDRLWERLGK 461
           ++ SAT     ++ L+ +I+  P  V + G   V   V    +V+    K  +L E LG 
Sbjct: 557 VMFSATFPR-AMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLG- 614

Query: 462 SHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDN 521
                             +  E  S  I + K E+A   +K                   
Sbjct: 615 ------------------HYQESGSVIIFVDKQEHADGLLK------------------- 637

Query: 522 LEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI 581
                       D     + C+ LHG    ++R   +  FK G  + L+ T VAARG+D+
Sbjct: 638 ------------DLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDV 685

Query: 582 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEK 625
             +  V+N + P+  ++YVHR GR GRA   G A + +  ++ +
Sbjct: 686 KHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQAR 729



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 4/76 (5%)

Query: 6   EMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVY 65
           + G+  +I  ++++  +  PT IQ ++IP I+ G D++  A+TGSGKT AF +P    ++
Sbjct: 376 QCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLP----MF 431

Query: 66  ETLKDQQEGKKGKTTI 81
             + DQ+  ++G+  I
Sbjct: 432 RHIMDQRSLEEGEGPI 447


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  115 bits (289), Expect = 1e-25
 Identities = 100/336 (29%), Positives = 155/336 (46%), Gaps = 57/336 (16%)

Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347
           +ALI+ P+RELA QTL   K+  K+     L+  LI+GG    DQ + L    DI++ TP
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTG---LKTALILGGDRMEDQFAALHENPDIIIATP 224

Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407
           GRL  +     L L  V ++V DEAD L   G+++ +  +  ++P         Q ++ S
Sbjct: 225 GRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGH------QTVLFS 278

Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTD 467
           ATL    V                  E +       V++ ++  T +L E+L     +T 
Sbjct: 279 ATLPKLLV------------------EFARAGLTEPVLIRLDVDT-KLNEQL-----KTS 314

Query: 468 DVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFI 527
               +++T+           A+ +      VR       DQ ++F  TK   + L +   
Sbjct: 315 FFLVREDTKA----------AVLLHLLHNVVRP-----QDQTVVFVATKHHAEYLTELLT 359

Query: 528 QQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYV 587
            Q         + SC  ++    P  RK NL +F  G    LI TD+AARG+DI  +  V
Sbjct: 360 TQ---------RVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNV 410

Query: 588 INVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEK 623
           IN + P + + ++HR+GRV RA R G A SLVA ++
Sbjct: 411 INYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDE 446



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 23/59 (38%), Positives = 37/59 (62%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           F  MG+   + + + +  + +PT IQ ++IP+IL G DV+  A TGSGKT  F +P+ +
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  115 bits (289), Expect = 1e-25
 Identities = 100/336 (29%), Positives = 155/336 (46%), Gaps = 57/336 (16%)

Query: 288 KALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTP 347
           +ALI+ P+RELA QTL   K+  K+     L+  LI+GG    DQ + L    DI++ TP
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTG---LKTALILGGDRMEDQFAALHENPDIIIATP 224

Query: 348 GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS 407
           GRL  +     L L  V ++V DEAD L   G+++ +  +  ++P         Q ++ S
Sbjct: 225 GRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGH------QTVLFS 278

Query: 408 ATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTD 467
           ATL    V                  E +       V++ ++  T +L E+L     +T 
Sbjct: 279 ATLPKLLV------------------EFARAGLTEPVLIRLDVDT-KLNEQL-----KTS 314

Query: 468 DVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFI 527
               +++T+           A+ +      VR       DQ ++F  TK   + L +   
Sbjct: 315 FFLVREDTKA----------AVLLHLLHNVVRP-----QDQTVVFVATKHHAEYLTELLT 359

Query: 528 QQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYV 587
            Q         + SC  ++    P  RK NL +F  G    LI TD+AARG+DI  +  V
Sbjct: 360 TQ---------RVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNV 410

Query: 588 INVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEK 623
           IN + P + + ++HR+GRV RA R G A SLVA ++
Sbjct: 411 INYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDE 446



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 23/59 (38%), Positives = 37/59 (62%)

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
           F  MG+   + + + +  + +PT IQ ++IP+IL G DV+  A TGSGKT  F +P+ +
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  114 bits (284), Expect = 4e-25
 Identities = 91/345 (26%), Positives = 151/345 (43%), Gaps = 64/345 (18%)

Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344
           N P  L++ P+RELA   L+   +  KY     L+ + I GG     Q+  +  GVDI++
Sbjct: 295 NGPGMLVLTPTRELA---LHVEAECSKY-SYKGLKSICIYGGRNRNGQIEDISKGVDIII 350

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
            TPGRL+DL     +NL  + +LV+DEAD +L   +   I ++                 
Sbjct: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKI----------------- 393

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
                    DV+   + +M   TW         PDTV                +L  S++
Sbjct: 394 -------LLDVRPDRQTVMTSATW---------PDTVR---------------QLALSYL 422

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKM---DQAIIFCRTKIDCDN 521
           +   +    N    A +    +  +   K + A+       M   D+ I+F   K   D+
Sbjct: 423 KDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADD 482

Query: 522 LEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI 581
           L   F  QG          S   LHG+ +  ++++ +E FK G+++ LI TD+ +RG+D+
Sbjct: 483 LSSDFNIQG---------ISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDL 533

Query: 582 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKV 626
           + V +V N   P     YVHR+G +GR  + G +++L+     K+
Sbjct: 534 NDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 17/49 (34%), Positives = 36/49 (73%)

Query: 11  PEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIP 59
           P++ +++  +  + PT IQ+++ P+IL G D+++ A+TG+GKT ++ +P
Sbjct: 231 PDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMP 279


>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
           [Homo sapiens]
          Length = 370

 Score =  113 bits (283), Expect = 6e-25
 Identities = 112/434 (25%), Positives = 187/434 (43%), Gaps = 106/434 (24%)

Query: 258 LSKAPDGYIVKSQHSGN-------AQVTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFK 310
           L++ P   I +SQ           A ++Q +     P+ L + P+ ELA QT   I+Q  
Sbjct: 18  LAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMG 77

Query: 311 KYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGK-LNLSQVRFLVL 369
           K+   P+L+    + G        + E    IV+GTPG + D  S  K ++  +++  VL
Sbjct: 78  KFY--PELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVL 132

Query: 370 DEADGLLS-QGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTW 428
           DEAD +++ QG+ D   R+   +P      +  Q+++ SAT     V K ++K++  P  
Sbjct: 133 DEADVMIATQGHQDQSIRIQRMLP------RNCQMLLFSATFED-SVWKFAQKVVPDPNV 185

Query: 429 VDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEA 488
           + LK E+   DT+    V  + + ++                                +A
Sbjct: 186 IKLKREEETLDTIKQYYVLCSSRDEKF-------------------------------QA 214

Query: 489 IKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGD 548
           +  L G   +         QA+IFC T+     L            K+GHQ +   L G+
Sbjct: 215 LCNLYGAITIA--------QAMIFCHTRKTASWLAAEL-------SKEGHQVAL--LSGE 257

Query: 549 RKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEK------QNYVHR 602
               +R   +ERF++G  + L+ T+V ARGID+  V  VIN  LP +K      + Y+HR
Sbjct: 258 MMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHR 317

Query: 603 IGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLSEI 662
           IGR GR  + GLA+++V ++                               + M +L+ I
Sbjct: 318 IGRTGRFGKRGLAVNMVDSK-------------------------------HSMNILNRI 346

Query: 663 EEHLNCTISQVEPD 676
           +EH N  I +++ D
Sbjct: 347 QEHFNKKIERLDTD 360


>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  113 bits (283), Expect = 6e-25
 Identities = 112/434 (25%), Positives = 187/434 (43%), Gaps = 106/434 (24%)

Query: 258 LSKAPDGYIVKSQHSGN-------AQVTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFK 310
           L++ P   I +SQ           A ++Q +     P+ L + P+ ELA QT   I+Q  
Sbjct: 127 LAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMG 186

Query: 311 KYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGK-LNLSQVRFLVL 369
           K+   P+L+    + G        + E    IV+GTPG + D  S  K ++  +++  VL
Sbjct: 187 KFY--PELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVL 241

Query: 370 DEADGLLS-QGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTW 428
           DEAD +++ QG+ D   R+   +P      +  Q+++ SAT     V K ++K++  P  
Sbjct: 242 DEADVMIATQGHQDQSIRIQRMLP------RNCQMLLFSATFED-SVWKFAQKVVPDPNV 294

Query: 429 VDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEA 488
           + LK E+   DT+    V  + + ++                                +A
Sbjct: 295 IKLKREEETLDTIKQYYVLCSSRDEKF-------------------------------QA 323

Query: 489 IKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGD 548
           +  L G   +         QA+IFC T+     L            K+GHQ +   L G+
Sbjct: 324 LCNLYGAITIA--------QAMIFCHTRKTASWLAAEL-------SKEGHQVAL--LSGE 366

Query: 549 RKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEK------QNYVHR 602
               +R   +ERF++G  + L+ T+V ARGID+  V  VIN  LP +K      + Y+HR
Sbjct: 367 MMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHR 426

Query: 603 IGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLSEI 662
           IGR GR  + GLA+++V ++                               + M +L+ I
Sbjct: 427 IGRTGRFGKRGLAVNMVDSK-------------------------------HSMNILNRI 455

Query: 663 EEHLNCTISQVEPD 676
           +EH N  I +++ D
Sbjct: 456 QEHFNKKIERLDTD 469



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 19/64 (29%), Positives = 39/64 (60%), Gaps = 2/64 (3%)

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILG--GGDVLMAAETGSGKTGAFSIPV 60
           +F E+ + P++ Q V  M +  P+ IQ  ++PL+L     +++  +++G+GKT AF + +
Sbjct: 93  SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 152

Query: 61  IQIV 64
           +  V
Sbjct: 153 LSQV 156


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  112 bits (281), Expect = 9e-25
 Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 57/335 (17%)

Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344
           + P A+IV P+REL +Q     K+F K  +   LR + + GG +  +Q   L+ G +IVV
Sbjct: 325 DGPIAVIVCPTRELCQQIHAECKRFGKAYN---LRSVAVYGGGSMWEQAKALQEGAEIVV 381

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
            TPGRL D V     NL +V +LV DEAD +   G+   +  + + +          Q +
Sbjct: 382 CTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR------QTL 435

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
           + SAT     ++KL+  I+  P  V           V   +   N    ++ E L     
Sbjct: 436 LFSATFRK-KIEKLARDILIDPIRV-----------VQGDIGEANEDVTQIVEILH---- 479

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524
                          + P  W+   +        R ++       ++F   K + + L  
Sbjct: 480 ---------------SGPSKWNWLTR--------RLVEFTSSGSVLLFVTKKANAEELAN 516

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
              Q+G       H      LHGD    ER + +  FKK D+  L+ TDVAARG+DI  +
Sbjct: 517 NLKQEG-------HNLGL--LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSI 567

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619
             VIN  +  +   + HRIGR GRA   G+A +L+
Sbjct: 568 KTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 20/60 (33%), Positives = 37/60 (61%)

Query: 2   AAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           ++F+  G   ++   + + ++  PT IQ + +P+ L G D++  A+TGSGKT AF  P++
Sbjct: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  112 bits (281), Expect = 9e-25
 Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 57/335 (17%)

Query: 285 NAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVV 344
           + P A+IV P+REL +Q     K+F K  +   LR + + GG +  +Q   L+ G +IVV
Sbjct: 325 DGPIAVIVCPTRELCQQIHAECKRFGKAYN---LRSVAVYGGGSMWEQAKALQEGAEIVV 381

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVI 404
            TPGRL D V     NL +V +LV DEAD +   G+   +  + + +          Q +
Sbjct: 382 CTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR------QTL 435

Query: 405 VCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHI 464
           + SAT     ++KL+  I+  P  V           V   +   N    ++ E L     
Sbjct: 436 LFSATFRK-KIEKLARDILIDPIRV-----------VQGDIGEANEDVTQIVEILH---- 479

Query: 465 RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524
                          + P  W+   +        R ++       ++F   K + + L  
Sbjct: 480 ---------------SGPSKWNWLTR--------RLVEFTSSGSVLLFVTKKANAEELAN 516

Query: 525 YFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
              Q+G       H      LHGD    ER + +  FKK D+  L+ TDVAARG+DI  +
Sbjct: 517 NLKQEG-------HNLGL--LHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSI 567

Query: 585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619
             VIN  +  +   + HRIGR GRA   G+A +L+
Sbjct: 568 KTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 20/60 (33%), Positives = 37/60 (61%)

Query: 2   AAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           ++F+  G   ++   + + ++  PT IQ + +P+ L G D++  A+TGSGKT AF  P++
Sbjct: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312


>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
           [Homo sapiens]
          Length = 448

 Score =  112 bits (280), Expect = 1e-24
 Identities = 114/440 (25%), Positives = 191/440 (43%), Gaps = 104/440 (23%)

Query: 245 EEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAEQTLN 304
           EE + P     +A S++  G   K+     A ++Q +     P+ L + P+ ELA QT  
Sbjct: 95  EELRLP--QNLIAQSQSGTG---KTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 149

Query: 305 NIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGK-LNLSQ 363
            I+Q  K+   P+L+    + G        + E    IV+GTPG + D  S  K ++  +
Sbjct: 150 VIEQMGKFY--PELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKK 204

Query: 364 VRFLVLDEADGLLS-QGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKI 422
           ++  VLDEAD +++ QG+ D   R+   +P      +  Q+++ SAT     V K ++K+
Sbjct: 205 IKVFVLDEADVMIATQGHQDQSIRIQRMLP------RNCQMLLFSATFED-SVWKFAQKV 257

Query: 423 MHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSP 482
           +  P  + LK E+   DT+    V  + + ++                            
Sbjct: 258 VPDPNVIKLKREEETLDTIKQYYVLCSSRDEKF--------------------------- 290

Query: 483 EMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSC 542
               +A+  L G   +         QA+IFC T+     L            K+GHQ + 
Sbjct: 291 ----QALCNLYGAITIA--------QAMIFCHTRKTASWLAAEL-------SKEGHQVAL 331

Query: 543 VCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEK------ 596
             L G+    +R   +ERF++G  + L+ T+V ARGID+  V  VIN  LP +K      
Sbjct: 332 --LSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 389

Query: 597 QNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEM 656
           + Y+HRIGR GR  + GLA+++V ++                               + M
Sbjct: 390 ETYLHRIGRTGRFGKRGLAVNMVDSK-------------------------------HSM 418

Query: 657 QLLSEIEEHLNCTISQVEPD 676
            +L+ I+EH N  I +++ D
Sbjct: 419 NILNRIQEHFNKKIERLDTD 438


>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
           isoform d [Homo sapiens]
          Length = 756

 Score =  112 bits (279), Expect = 2e-24
 Identities = 59/165 (35%), Positives = 93/165 (56%), Gaps = 23/165 (13%)

Query: 97  DRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCH-------------DQG 143
           DR S + +  +G          W G RA+ G+ +G+  +E+  +             D  
Sbjct: 127 DRSSGYPLTIEGFAYL------WSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPH 180

Query: 144 LCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFDNYGEEFTMHDTIGCYLDIDKGH- 202
           + R+GWS    S  LG + F +G+GGTGKKS N +F+NYG++F  +D IGC+ D + G+ 
Sbjct: 181 VVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGND 240

Query: 203 --VKFSKNGKDLGLAFEIPPH-MKNQALFPACVLKNAELKFNFGE 244
             + F+KNGK +G+AF I    +  QAL+P  ++KN  ++FNFG+
Sbjct: 241 VELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQ 285


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,248,578
Number of Sequences: 37866
Number of extensions: 1352755
Number of successful extensions: 2829
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2545
Number of HSP's gapped (non-prelim): 211
length of query: 740
length of database: 18,247,518
effective HSP length: 110
effective length of query: 630
effective length of database: 14,082,258
effective search space: 8871822540
effective search space used: 8871822540
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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