Search of human proteins with 4759188

Search of human proteins with 4759188

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759188 syntaxin 8 [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759188 syntaxin 8 [Homo sapiens]                                  459   e-130
gi|5032131 syntaxin 6 [Homo sapiens]                                   57   1e-08
gi|4507285 syntaxin 10 [Homo sapiens]                                  52   4e-07
gi|170932494 syntaxin 7 [Homo sapiens]                                 47   2e-05
gi|219555661 intraflagellar transport 81-like isoform 1 [Homo sa...    42   5e-04
gi|32526901 intraflagellar transport 81-like isoform 1 [Homo sap...    42   5e-04
gi|148746195 trichohyalin [Homo sapiens]                               39   0.005
gi|153791839 sodium channel associated protein 1 [Homo sapiens]        39   0.005
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       38   0.007
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       38   0.007
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        38   0.007
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        38   0.007
gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]           38   0.007
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    37   0.015
gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B [...    37   0.015
gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A [...    37   0.015
gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]               36   0.025
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    36   0.025
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]              35   0.073
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    35   0.073
gi|47778943 syntaxin 16 isoform a [Homo sapiens]                       35   0.073
gi|198041692 syntaxin 16 isoform d [Homo sapiens]                      35   0.073
gi|198041688 syntaxin 16 isoform c [Homo sapiens]                      35   0.073
gi|34447229 syntaxin 16 isoform b [Homo sapiens]                       35   0.073
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    35   0.073
gi|5454166 vesicle transport through interaction with t-SNAREs 1...    34   0.13 
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    33   0.16 
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C...    33   0.16 
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi...    33   0.16 
gi|21735548 centrosomal protein 2 [Homo sapiens]                       33   0.21 

>gi|4759188 syntaxin 8 [Homo sapiens]
          Length = 236

 Score =  459 bits (1181), Expect = e-130
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MAPDPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKD 60
           MAPDPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKD
Sbjct: 1   MAPDPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKD 60

Query: 61  LLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGA 120
           LLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGA
Sbjct: 61  LLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGA 120

Query: 121 PNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQN 180
           PNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQN
Sbjct: 121 PNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQN 180

Query: 181 EIIDDLANLVENTDEKLRNETRRVNMVDRKSASCGMIMVILLLLVAIVVVAVWPTN 236
           EIIDDLANLVENTDEKLRNETRRVNMVDRKSASCGMIMVILLLLVAIVVVAVWPTN
Sbjct: 181 EIIDDLANLVENTDEKLRNETRRVNMVDRKSASCGMIMVILLLLVAIVVVAVWPTN 236


>gi|5032131 syntaxin 6 [Homo sapiens]
          Length = 255

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 30/99 (30%), Positives = 58/99 (58%), Gaps = 4/99 (4%)

Query: 138 DEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKL 197
           +E + QQQ I+++QD  L+ +S  I   K M Q IG EL+EQ  +++D ++ +E+T  +L
Sbjct: 156 EEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRL 215

Query: 198 RNETRRVNMVDRKSAS----CGMIMVILLLLVAIVVVAV 232
            N  +++  V   ++     C + ++  +LLV +++  V
Sbjct: 216 DNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLV 254


>gi|4507285 syntaxin 10 [Homo sapiens]
          Length = 249

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 56/239 (23%), Positives = 103/239 (43%), Gaps = 30/239 (12%)

Query: 10  YDSTCQIAQEIA----EKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRA 65
           Y   C++ QE A    E++       R G ++      I   L++L+E I +++      
Sbjct: 25  YQRWCELLQESAAVGREELDWTTNELRNGLRS------IEWDLEDLEETIGIVE------ 72

Query: 66  VSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLI-------RSSLMSEEAKR 118
            +  +     GD ++  +   V R R  +   K+    P  +       R  L  + A +
Sbjct: 73  ANPGKFKLPAGDLQERKV--FVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQ 130

Query: 119 GAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDE 178
            +P+  L            +E +  QQ I+ EQD  L+ +S  I   K M   +G ELDE
Sbjct: 131 KSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDE 190

Query: 179 QNEIIDDLANLVENTDEKLRNETRRVNMV-----DRKSASCGMIMVILLLLVAIVVVAV 232
           Q  ++D  A  +++T  ++    R++  V     DR+      ++V +LLLV I++ ++
Sbjct: 191 QGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLLLVLILLFSL 249


>gi|170932494 syntaxin 7 [Homo sapiens]
          Length = 261

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/226 (19%), Positives = 105/226 (46%), Gaps = 16/226 (7%)

Query: 15  QIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQL 74
           ++ Q++ +K Q  NQ  ++ +K  K   ++       +++  + KD L+   +T  +T  
Sbjct: 47  ELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQR-KIQKDRLVAEFTT-SLTNF 104

Query: 75  EGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRG 134
           +  +RQ        RE+  +A  +        +  S   + +K      W  +   + + 
Sbjct: 105 QKVQRQ-----AAEREKEFVARVRASSR----VSGSFPEDSSKERNLVSWESQTQPQVQ- 154

Query: 135 LGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTD 194
           +  +EI +   ++I E+++ +  L + I    ++ +++G  + EQ ++ID +   VEN +
Sbjct: 155 VQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAE 214

Query: 195 ---EKLRNETRRVNMVDRKSASCGMIMVILLLL-VAIVVVAVWPTN 236
              ++   +  R     RKS     I++++L++ VAI+ + +W  N
Sbjct: 215 VHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLIIWGLN 260


>gi|219555661 intraflagellar transport 81-like isoform 1 [Homo
           sapiens]
          Length = 676

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 43/201 (21%), Positives = 83/201 (41%), Gaps = 21/201 (10%)

Query: 11  DSTCQIAQEIAEKIQQRNQYER----KGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAV 66
           +    + +E + K  Q  +++     KG++  +    +R+     K+K  ++ +L     
Sbjct: 367 EKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEFG 426

Query: 67  STHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLF 126
              +  +L   R +N+   L T E            +  +   S   EE +R +    L 
Sbjct: 427 LLQRTEELLKQRHENIQQQLQTMEE-----------KKGISGYSYTQEELERVSA---LK 472

Query: 127 EEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQ---EIGNELDEQNEII 183
            E +E +G   D++ +  +K+         AL+S+I   +Q+ Q   E+  E DE+    
Sbjct: 473 SEVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQY 532

Query: 184 DDLANLVENTDEKLRNETRRV 204
           D  A  +E+   KL  E RR+
Sbjct: 533 DSCAAGLESNRSKLEQEVRRL 553


>gi|32526901 intraflagellar transport 81-like isoform 1 [Homo
           sapiens]
          Length = 676

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 43/201 (21%), Positives = 83/201 (41%), Gaps = 21/201 (10%)

Query: 11  DSTCQIAQEIAEKIQQRNQYER----KGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAV 66
           +    + +E + K  Q  +++     KG++  +    +R+     K+K  ++ +L     
Sbjct: 367 EKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEFG 426

Query: 67  STHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLF 126
              +  +L   R +N+   L T E            +  +   S   EE +R +    L 
Sbjct: 427 LLQRTEELLKQRHENIQQQLQTMEE-----------KKGISGYSYTQEELERVSA---LK 472

Query: 127 EEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQ---EIGNELDEQNEII 183
            E +E +G   D++ +  +K+         AL+S+I   +Q+ Q   E+  E DE+    
Sbjct: 473 SEVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQY 532

Query: 184 DDLANLVENTDEKLRNETRRV 204
           D  A  +E+   KL  E RR+
Sbjct: 533 DSCAAGLESNRSKLEQEVRRL 553


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 43/186 (23%), Positives = 80/186 (43%), Gaps = 23/186 (12%)

Query: 15   QIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQL 74
            Q+ +E  EK ++R ++ER+  K  +L      LL+  +EK  L                 
Sbjct: 1002 QLLREEREK-RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ---------------- 1044

Query: 75   EGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRG 134
            E +R+    ++L   E  LL   +      +L R     EE ++      L EEPE+ R 
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ-EEEQLLREEPEKRRR 1103

Query: 135  LGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTD 194
               +   ++++++ QE++  L        R+K+  QE+  +  E+ E+  +   L+    
Sbjct: 1104 QERERQCREEEELQQEEEQLLRE-----EREKRRRQELERQYREEEEVQQEEEQLLREEP 1158

Query: 195  EKLRNE 200
            EK R +
Sbjct: 1159 EKRRRQ 1164



 Score = 28.5 bits (62), Expect = 5.3
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 11/93 (11%)

Query: 111 LMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQ 170
           L  EE +R      L EE E+ R L   E+R+++Q+  Q+Q          + R++Q+ +
Sbjct: 260 LQEEEPQRQRE---LQEEEEQLRKLERQELRRERQEEEQQQQR--------LRREQQLRR 308

Query: 171 EIGNELDEQNEIIDDLANLVENTDEKLRNETRR 203
           +   E  EQ E   +     E  +E+   + RR
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRR 341


>gi|153791839 sodium channel associated protein 1 [Homo sapiens]
          Length = 688

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 19/81 (23%), Positives = 44/81 (54%)

Query: 141 RQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNE 200
           +++ +K+ +  +  ++ L S +SRQK   QE+ ++L+  NE + +   L+    EK    
Sbjct: 592 KEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVAENEKLILEHQEKANRL 651

Query: 201 TRRVNMVDRKSASCGMIMVIL 221
            RR++  + ++AS    + ++
Sbjct: 652 QRRLSQAEERAASASQQLSVI 672


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 44/189 (23%), Positives = 85/189 (44%), Gaps = 15/189 (7%)

Query: 15  QIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQL 74
           ++A+E AE +QQ  + E   E+  +LT  +  L   ++EK +        A S++Q+ QL
Sbjct: 178 EMAEERAESLQQ--EVEALKERVDELTTDLEILKAEIEEKGSD------GAASSYQLKQL 229

Query: 75  EGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRG 134
           E    +  L D + R R L +S K E  +   +      E          L EE  +   
Sbjct: 230 EEQNAR--LKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 287

Query: 135 LGFDEIRQQQQKIIQEQDAG---LDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVE 191
              DE+++Q    +  ++      D   ++  + +++ + +G +L+  NE+ D+L     
Sbjct: 288 T-IDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVG-DLEAMNEMNDELQENAR 345

Query: 192 NTDEKLRNE 200
            T+ +LR +
Sbjct: 346 ETELELREQ 354


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 44/189 (23%), Positives = 85/189 (44%), Gaps = 15/189 (7%)

Query: 15  QIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQL 74
           ++A+E AE +QQ  + E   E+  +LT  +  L   ++EK +        A S++Q+ QL
Sbjct: 292 EMAEERAESLQQ--EVEALKERVDELTTDLEILKAEIEEKGSD------GAASSYQLKQL 343

Query: 75  EGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRG 134
           E    +  L D + R R L +S K E  +   +      E          L EE  +   
Sbjct: 344 EEQNAR--LKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 401

Query: 135 LGFDEIRQQQQKIIQEQDAG---LDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVE 191
              DE+++Q    +  ++      D   ++  + +++ + +G +L+  NE+ D+L     
Sbjct: 402 T-IDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVG-DLEAMNEMNDELQENAR 459

Query: 192 NTDEKLRNE 200
            T+ +LR +
Sbjct: 460 ETELELREQ 468


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 44/189 (23%), Positives = 85/189 (44%), Gaps = 15/189 (7%)

Query: 15  QIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQL 74
           ++A+E AE +QQ  + E   E+  +LT  +  L   ++EK +        A S++Q+ QL
Sbjct: 178 EMAEERAESLQQ--EVEALKERVDELTTDLEILKAEIEEKGSD------GAASSYQLKQL 229

Query: 75  EGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRG 134
           E    +  L D + R R L +S K E  +   +      E          L EE  +   
Sbjct: 230 EEQNAR--LKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 287

Query: 135 LGFDEIRQQQQKIIQEQDAG---LDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVE 191
              DE+++Q    +  ++      D   ++  + +++ + +G +L+  NE+ D+L     
Sbjct: 288 T-IDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVG-DLEAMNEMNDELQENAR 345

Query: 192 NTDEKLRNE 200
            T+ +LR +
Sbjct: 346 ETELELREQ 354


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 44/189 (23%), Positives = 85/189 (44%), Gaps = 15/189 (7%)

Query: 15  QIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQL 74
           ++A+E AE +QQ  + E   E+  +LT  +  L   ++EK +        A S++Q+ QL
Sbjct: 312 EMAEERAESLQQ--EVEALKERVDELTTDLEILKAEIEEKGSD------GAASSYQLKQL 363

Query: 75  EGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRG 134
           E    +  L D + R R L +S K E  +   +      E          L EE  +   
Sbjct: 364 EEQNAR--LKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 421

Query: 135 LGFDEIRQQQQKIIQEQDAG---LDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVE 191
              DE+++Q    +  ++      D   ++  + +++ + +G +L+  NE+ D+L     
Sbjct: 422 T-IDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVG-DLEAMNEMNDELQENAR 479

Query: 192 NTDEKLRNE 200
            T+ +LR +
Sbjct: 480 ETELELREQ 488


>gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]
          Length = 258

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 4/68 (5%)

Query: 140 IRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRN 199
           +R   QKI    D+ LD LS  + R K +   +  E++EQ++I+D L   V+  D  +++
Sbjct: 195 LRAYHQKI----DSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKS 250

Query: 200 ETRRVNMV 207
             R+V  +
Sbjct: 251 TERKVRQL 258


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 41/197 (20%), Positives = 90/197 (45%), Gaps = 11/197 (5%)

Query: 19  EIAEKIQ-QRNQYERKGEKAPKLTVTIRALLQNL---KEKIALLKDLLLRAVSTHQITQL 74
           E  EKI+ Q  +  R+ EK  +    IR   + +   +EKI   +++       H+  ++
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559

Query: 75  -EGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETR 133
            E ++RQ   D +  +E  +    +    + + IR     +E KR      ++++ E+ R
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE----QEEKRQEQEEKMWKQEEKIR 615

Query: 134 GLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENT 193
               +E  Q+Q++ I+EQ+  +     +   Q++   E   ++ EQ E + +    +   
Sbjct: 616 EQ--EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673

Query: 194 DEKLRNETRRVNMVDRK 210
           +EK+R + +++   + K
Sbjct: 674 EEKIREQEKKIREQEEK 690



 Score = 35.4 bits (80), Expect = 0.043
 Identities = 22/93 (23%), Positives = 48/93 (51%), Gaps = 8/93 (8%)

Query: 112 MSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQE 171
           M E+ ++        +E EET     ++IR+Q++KI ++++         I  Q++M QE
Sbjct: 649 MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK--------IREQEEMMQE 700

Query: 172 IGNELDEQNEIIDDLANLVENTDEKLRNETRRV 204
              ++ EQ E + +    ++  +EK+R +  ++
Sbjct: 701 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733



 Score = 28.9 bits (63), Expect = 4.0
 Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 17/161 (10%)

Query: 49  QNLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIR 108
           + LKEK A L++ L    S     QL     +  L+    R +LLL   + + AE D + 
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE----RAKLLLPQQQLQ-AEADHLG 271

Query: 109 SSLMSEEAKRGAP----NPW--LFEEPEETRGLGFDEIRQQQQKI------IQEQDAGLD 156
             L S  AK  A       W  L ++ EE      ++I++ ++KI      I+EQ+  + 
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331

Query: 157 ALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKL 197
                + RQ++M  E   ++  Q E++ +    +   +E +
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372


>gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B
           [Homo sapiens]
          Length = 206

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 44/199 (22%), Positives = 83/199 (41%), Gaps = 16/199 (8%)

Query: 20  IAEKIQQRNQYERKGEKAPKLT----VTIRALLQNLKE-KIALLKDLLLRAVSTHQITQL 74
           +AE    RN+ E    +A +L      + R +LQ ++E K A ++ L++      Q+ ++
Sbjct: 1   MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERI 60

Query: 75  EGDRRQNLLDDLVTRERLLLASFK---------NEGAEPDLIRSSLMSEEAKRGAPNPWL 125
           E    Q +  D+   E+ L    K         N+    D  + +  + +    A  P  
Sbjct: 61  EEGMDQ-INKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPAR 119

Query: 126 FEEPEETRGLGFDEIRQQQQKIIQ-EQDAGLDALSSIISRQKQMGQEIGNELDEQNEIID 184
             +  E   +    IR+      + E D  L+ +S II   + M  ++GNE+D QN  ID
Sbjct: 120 VVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQID 179

Query: 185 DLANLVENTDEKLRNETRR 203
            +    ++   ++    +R
Sbjct: 180 RIMEKADSNKTRIDEANQR 198


>gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A
           [Homo sapiens]
          Length = 206

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 16/199 (8%)

Query: 20  IAEKIQQRNQYERKGEKAPKLT----VTIRALLQNLKE-KIALLKDLLLRAVSTHQITQL 74
           +AE    RN+ E    +A +L      + R +LQ ++E K A ++ L++      Q+ ++
Sbjct: 1   MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRV 60

Query: 75  EGDRRQNLLDDLVTRERLLLASFK---------NEGAEPDLIRSSLMSEEAKRGAPNPWL 125
           E +   ++  D+   E+ L    K         N+    D  + +  + +    A  P  
Sbjct: 61  E-EGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPAR 119

Query: 126 FEEPEETRGLGFDEIRQQQQKIIQ-EQDAGLDALSSIISRQKQMGQEIGNELDEQNEIID 184
             +  E   +    IR+      + E D  L+ +S II   + M  ++GNE+D QN  ID
Sbjct: 120 VVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQID 179

Query: 185 DLANLVENTDEKLRNETRR 203
            +    ++   ++    +R
Sbjct: 180 RIMEKADSNKTRIDEANQR 198


>gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]
          Length = 1464

 Score = 36.2 bits (82), Expect = 0.025
 Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 15/144 (10%)

Query: 50  NLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRS 109
           +LKEK  +L  LL  + S   + +L  +          T + L   S          I+ 
Sbjct: 682 SLKEKHKILHRLLQDSSSPVDLAKLTAE---------ATGKDLSQESSSTAPGSEVTIKQ 732

Query: 110 SLMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQD-AGLDALSSIISRQKQM 168
             +S + K  A   +L ++ ++T+ +G  EI  + +++  + D A    L ++ + +++M
Sbjct: 733 EPVSPKKKENALLRYLLDK-DDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTEKEEM 791

Query: 169 ----GQEIGNELDEQNEIIDDLAN 188
               G + G+ELD   EI+DDL N
Sbjct: 792 SFEPGDQPGSELDNLEEILDDLQN 815


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 36.2 bits (82), Expect = 0.025
 Identities = 41/160 (25%), Positives = 74/160 (46%), Gaps = 12/160 (7%)

Query: 49  QNLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIR 108
           + LKEK A L++ L    S     QL     +  L+    R +LLL   + + AE D + 
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE----RAKLLLPQQQLQ-AEADHLG 259

Query: 109 SSLMSEEAKRGAP----NPW--LFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSII 162
             L S  AK  A       W  L ++ EE      ++I+++++K IQEQ+  +      +
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEK-IQEQEEKIREQEEKM 318

Query: 163 SRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETR 202
            RQ++M  E   ++  Q E++ +    +   +EK+  + +
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 358



 Score = 34.7 bits (78), Expect = 0.073
 Identities = 36/198 (18%), Positives = 86/198 (43%), Gaps = 10/198 (5%)

Query: 22  EKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQLEGDRRQN 81
           EKI+++ + + +  K  +    IR   + ++E+  ++++   +     +    + +  Q 
Sbjct: 370 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429

Query: 82  LLDDLVTRERLLLASFKNEGAEPDLIRSS---LMSEEAKRGAPNPWLFE------EPEET 132
             + +  +E  +    K    + + IR     +  +E K G     + E      E EE 
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489

Query: 133 RGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVEN 192
                ++IR+Q++K I+EQ+  +     ++  Q++   E   ++ EQ E + +    +  
Sbjct: 490 MRRQEEKIREQEKK-IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548

Query: 193 TDEKLRNETRRVNMVDRK 210
            +EK+R +  R+   + K
Sbjct: 549 QEEKMREQEVRLRQQEEK 566


>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
          Length = 636

 Score = 34.7 bits (78), Expect = 0.073
 Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 23/172 (13%)

Query: 45  RALLQNLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEP 104
           R++ Q  ++KI  L+  L  A    Q+T LE +R Q   D      +LLLA  K E  E 
Sbjct: 325 RSMKQQYEQKITELRQKL--ADLQKQVTDLEAEREQKQRD---FDRKLLLAKSKIEMEET 379

Query: 105 DLIRSSLMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISR 164
           D  +  L +E  +      +L ++            R+ Q+K IQ  +  L+   SI + 
Sbjct: 380 D--KEQLTAEAKELRQKVKYLQDQLSP-----LTRQREYQEKEIQRLNKALEEALSIQTP 432

Query: 165 QKQMGQEIGN-----------ELDEQNEIIDDLANLVENTDEKLRNETRRVN 205
                   G+           EL  QNE++     + E   ++ R++  R+N
Sbjct: 433 PSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMN 484


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 34.7 bits (78), Expect = 0.073
 Identities = 20/83 (24%), Positives = 44/83 (53%), Gaps = 8/83 (9%)

Query: 128 EPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLA 187
           E EE      ++IR+Q++KI ++++         I  Q++M QE   ++ EQ E + +  
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEK--------IREQEEMTQEQEEKMGEQEEKMCEQE 626

Query: 188 NLVENTDEKLRNETRRVNMVDRK 210
             ++  +EK+R +  ++   ++K
Sbjct: 627 EKMQEQEEKMRRQEEKIREQEKK 649



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 17/174 (9%)

Query: 49  QNLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIR 108
           + LKEK A L++ L    S     QL     +  L+    R +LLL   + + AE D + 
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE----RAKLLLPQQQLQ-AEADHLG 332

Query: 109 SSLMSEEAKRGAP----NPW--LFEEPEETRGLGFDEIRQQQQKI------IQEQDAGLD 156
             L S  AK  A       W  L ++ EE      ++I++ ++KI      I+EQ+  + 
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 392

Query: 157 ALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRVNMVDRK 210
                + RQ++M  E   ++  Q E++ +    +   +E +  +  ++  ++ K
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446



 Score = 31.2 bits (69), Expect = 0.81
 Identities = 23/93 (24%), Positives = 47/93 (50%), Gaps = 8/93 (8%)

Query: 112 MSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQE 171
           M E+ ++        +E EE      ++IR+Q++K I+EQ+         I  Q++M QE
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK-IREQE-------EKIREQEEMMQE 666

Query: 172 IGNELDEQNEIIDDLANLVENTDEKLRNETRRV 204
              ++ EQ E + +    ++  +EK+R +  ++
Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699


>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
          Length = 325

 Score = 34.7 bits (78), Expect = 0.073
 Identities = 19/91 (20%), Positives = 49/91 (53%)

Query: 142 QQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNET 201
           +Q   +++E++  +  +   IS   ++ +++G  + EQ  ++D +   VE +  K  +  
Sbjct: 227 EQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGL 286

Query: 202 RRVNMVDRKSASCGMIMVILLLLVAIVVVAV 232
           ++++  ++       ++VIL+L V I+V+ V
Sbjct: 287 KQLHKAEQYQKKNRKMLVILILFVIIIVLIV 317


>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
          Length = 308

 Score = 34.7 bits (78), Expect = 0.073
 Identities = 19/91 (20%), Positives = 49/91 (53%)

Query: 142 QQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNET 201
           +Q   +++E++  +  +   IS   ++ +++G  + EQ  ++D +   VE +  K  +  
Sbjct: 210 EQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGL 269

Query: 202 RRVNMVDRKSASCGMIMVILLLLVAIVVVAV 232
           ++++  ++       ++VIL+L V I+V+ V
Sbjct: 270 KQLHKAEQYQKKNRKMLVILILFVIIIVLIV 300


>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
          Length = 321

 Score = 34.7 bits (78), Expect = 0.073
 Identities = 19/91 (20%), Positives = 49/91 (53%)

Query: 142 QQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNET 201
           +Q   +++E++  +  +   IS   ++ +++G  + EQ  ++D +   VE +  K  +  
Sbjct: 223 EQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGL 282

Query: 202 RRVNMVDRKSASCGMIMVILLLLVAIVVVAV 232
           ++++  ++       ++VIL+L V I+V+ V
Sbjct: 283 KQLHKAEQYQKKNRKMLVILILFVIIIVLIV 313


>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
          Length = 304

 Score = 34.7 bits (78), Expect = 0.073
 Identities = 19/91 (20%), Positives = 49/91 (53%)

Query: 142 QQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNET 201
           +Q   +++E++  +  +   IS   ++ +++G  + EQ  ++D +   VE +  K  +  
Sbjct: 206 EQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGL 265

Query: 202 RRVNMVDRKSASCGMIMVILLLLVAIVVVAV 232
           ++++  ++       ++VIL+L V I+V+ V
Sbjct: 266 KQLHKAEQYQKKNRKMLVILILFVIIIVLIV 296


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 34.7 bits (78), Expect = 0.073
 Identities = 50/226 (22%), Positives = 98/226 (43%), Gaps = 48/226 (21%)

Query: 15  QIAQEIAEKIQQRNQYER--KGEKAP------KLTVTIRAL----------LQNLKEKIA 56
           Q+ + + +   +R++Y +  KGE+A       K++V  R L          +Q L+  ++
Sbjct: 217 QVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLS 276

Query: 57  LLKDLLLRAVS------THQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSS 110
            LK+ + +  S      T  + QL+ D  ++L  ++   E  L +  +N  A       S
Sbjct: 277 ELKNQMAKPPSLAPPAVTSVVEQLQ-DEAKHLRQEVEGLEGKLQSQVENNQA------LS 329

Query: 111 LMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQ------------QQKIIQEQDAGLDAL 158
           L+S+E K+      L E+ E  R      +R+Q            QQK +QEQ   L   
Sbjct: 330 LLSKEQKQR-----LQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384

Query: 159 SSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRV 204
              + +Q++  ++    L +Q + + D    +   +E+L+ +  R+
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430


>gi|5454166 vesicle transport through interaction with t-SNAREs 1B
           [Homo sapiens]
          Length = 232

 Score = 33.9 bits (76), Expect = 0.13
 Identities = 18/64 (28%), Positives = 34/64 (53%)

Query: 161 IISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRVNMVDRKSASCGMIMVI 220
           I +   Q+G EI  EL EQ + ++   + + NT E L    + +  + RK  +  +++ I
Sbjct: 152 IATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSI 211

Query: 221 LLLL 224
           ++LL
Sbjct: 212 IILL 215


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 50/226 (22%), Positives = 97/226 (42%), Gaps = 48/226 (21%)

Query: 15  QIAQEIAEKIQQRNQYER--KGEKAP------KLTVTIRAL----------LQNLKEKIA 56
           Q+ + + +   +R++Y +  KGE+A       K++V  R L          +Q L+  ++
Sbjct: 217 QVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLS 276

Query: 57  LLKDLLLRAVS------THQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSS 110
            LK+ +    S      T  + QL+ D  ++L  ++   E  L +  +N  A       S
Sbjct: 277 ELKNQMAEPPSLAPPAVTSVVEQLQ-DEAKHLRQEVEGLEGKLQSQVENNQA------LS 329

Query: 111 LMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQ------------QQKIIQEQDAGLDAL 158
           L+S+E K+      L E+ E  R      +R+Q            QQK +QEQ   L   
Sbjct: 330 LLSKEQKQR-----LQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384

Query: 159 SSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRV 204
              + +Q++  ++    L +Q + + D    +   +E+L+ +  R+
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430


>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
           isoform 1 [Homo sapiens]
          Length = 693

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 50/226 (22%), Positives = 97/226 (42%), Gaps = 48/226 (21%)

Query: 15  QIAQEIAEKIQQRNQYER--KGEKAP------KLTVTIRAL----------LQNLKEKIA 56
           Q+ + + +   +R++Y +  KGE+A       K++V  R L          +Q L+  ++
Sbjct: 217 QVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLS 276

Query: 57  LLKDLLLRAVS------THQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSS 110
            LK+ +    S      T  + QL+ D  ++L  ++   E  L +  +N  A       S
Sbjct: 277 ELKNQMAEPPSLAPPAVTSVVEQLQ-DEAKHLRQEVEGLEGKLQSQVENNQA------LS 329

Query: 111 LMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQ------------QQKIIQEQDAGLDAL 158
           L+S+E K+      L E+ E  R      +R+Q            QQK +QEQ   L   
Sbjct: 330 LLSKEQKQR-----LQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384

Query: 159 SSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRV 204
              + +Q++  ++    L +Q + + D    +   +E+L+ +  R+
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430


>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
           sapiens]
          Length = 693

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 50/226 (22%), Positives = 97/226 (42%), Gaps = 48/226 (21%)

Query: 15  QIAQEIAEKIQQRNQYER--KGEKAP------KLTVTIRAL----------LQNLKEKIA 56
           Q+ + + +   +R++Y +  KGE+A       K++V  R L          +Q L+  ++
Sbjct: 217 QVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLS 276

Query: 57  LLKDLLLRAVS------THQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSS 110
            LK+ +    S      T  + QL+ D  ++L  ++   E  L +  +N  A       S
Sbjct: 277 ELKNQMAEPPSLAPPAVTSVVEQLQ-DEAKHLRQEVEGLEGKLQSQVENNQA------LS 329

Query: 111 LMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQ------------QQKIIQEQDAGLDAL 158
           L+S+E K+      L E+ E  R      +R+Q            QQK +QEQ   L   
Sbjct: 330 LLSKEQKQR-----LQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384

Query: 159 SSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRV 204
              + +Q++  ++    L +Q + + D    +   +E+L+ +  R+
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 33.1 bits (74), Expect = 0.21
 Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 16/137 (11%)

Query: 22   EKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQLEGDRRQN 81
            E+ Q + Q ER  EKA  L   +      LKE+   L+D   +A    +   +EG R Q 
Sbjct: 1825 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQA 1884

Query: 82   LLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRGLGFDEIR 141
            L +        +L   + E  E +    +L  + A++        E   ETR L   +  
Sbjct: 1885 LEE--------VLGDLRAESREQEKALLALQQQCAEQAQ------EHEVETRAL--QDSW 1928

Query: 142  QQQQKIIQEQDAGLDAL 158
             Q Q +++E+D  L+AL
Sbjct: 1929 LQAQAVLKERDQELEAL 1945



 Score = 31.2 bits (69), Expect = 0.81
 Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 18/178 (10%)

Query: 45   RALLQNLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEP 104
            R LLQ  KE +    + L  AV      + +      L +DL T    L    KNE  E 
Sbjct: 1343 RELLQAAKENLTAQVEHLQAAVVE---ARAQASAAGILEEDLRTARSAL--KLKNEEVES 1397

Query: 105  DLIRSSLMSEEA-------KRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQE---QDAG 154
            +  R+  + E+        K    N  L  +    R    + +R Q Q++ ++   Q A 
Sbjct: 1398 ERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAA 1457

Query: 155  LDALSSIISRQKQ---MGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRVNMVDR 209
            L+ LS  + ++ Q   + QE   EL++   +++ L   V+  ++KL  +  ++  +++
Sbjct: 1458 LELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEK 1515



 Score = 28.9 bits (63), Expect = 4.0
 Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 12/140 (8%)

Query: 73   QLEGDR-RQNLLDDLV-TRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPE 130
            QLE ++ R +LL+ L+ T++ L  AS + E    D+ +   + E+   G     L E   
Sbjct: 920  QLETEKERVSLLETLLQTQKELADASQQLERLRQDM-KVQKLKEQETTGILQTQLQEAQR 978

Query: 131  ETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLV 190
            E +    +  RQ +  +   Q+     L   +  QKQ+      +L  Q    DD   LV
Sbjct: 979  ELK----EAARQHRDDLAALQEESSSLLQDKMDLQKQV-----EDLKSQLVAQDDSQRLV 1029

Query: 191  ENTDEKLRNETRRVNMVDRK 210
            E   ++   ET+  N + ++
Sbjct: 1030 EQEVQEKLRETQEYNRIQKE 1049



 Score = 28.9 bits (63), Expect = 4.0
 Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 18/125 (14%)

Query: 11   DSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKD---------- 60
            DS   + QE+ EK+++  +Y R  ++  +   ++   L   ++++ +L++          
Sbjct: 1024 DSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELS 1083

Query: 61   LLLRAVSTHQITQLEGDRRQNLL--------DDLVTRERLLLASFKNEGAEPDLIRSSLM 112
             L + +   Q  Q E   +  LL         D + +E  LL   +        +R+SL 
Sbjct: 1084 ALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLW 1143

Query: 113  SEEAK 117
            ++EAK
Sbjct: 1144 AQEAK 1148


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,785,199
Number of Sequences: 37866
Number of extensions: 317817
Number of successful extensions: 1895
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 1727
Number of HSP's gapped (non-prelim): 279
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.