BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1 precursor [Homo sapiens] (535 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1 pr... 1089 0.0 gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1 prec... 1089 0.0 gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2 pr... 1055 0.0 gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 1055 0.0 gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 1055 0.0 gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1 prec... 712 0.0 gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2 pre... 702 0.0 gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2 prec... 702 0.0 gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3 pre... 663 0.0 gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [H... 329 4e-90 gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isofor... 72 2e-12 gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isofor... 53 8e-07 gi|197313662 leprecan-like 1 isoform b [Homo sapiens] 36 0.077 gi|27764882 leprecan-like 1 isoform a [Homo sapiens] 36 0.077 gi|5454038 synaptonemal complex protein SC65 [Homo sapiens] 34 0.38 gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 33 0.85 gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 33 0.85 gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 33 0.85 gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 32 1.9 gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 30 4.2 gi|29788755 SET binding factor 2 [Homo sapiens] 30 4.2 gi|166795301 prenylcysteine oxidase 1 [Homo sapiens] 30 5.5 gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 30 5.5 gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 30 5.5 gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 30 5.5 gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 30 5.5 gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 30 5.5 gi|163659918 sacsin [Homo sapiens] 30 7.2 gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 30 7.2 gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 30 7.2 >gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1 precursor [Homo sapiens] Length = 535 Score = 1089 bits (2816), Expect = 0.0 Identities = 535/535 (100%), Positives = 535/535 (100%) Query: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS Sbjct: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 Query: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR Sbjct: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 Query: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK Sbjct: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480 Query: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD Sbjct: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 >gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1 precursor [Homo sapiens] Length = 535 Score = 1089 bits (2816), Expect = 0.0 Identities = 535/535 (100%), Positives = 535/535 (100%) Query: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS Sbjct: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 Query: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR Sbjct: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 Query: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK Sbjct: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480 Query: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD Sbjct: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 >gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2 precursor [Homo sapiens] Length = 533 Score = 1055 bits (2727), Expect = 0.0 Identities = 523/535 (97%), Positives = 524/535 (97%), Gaps = 2/535 (0%) Query: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS Sbjct: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 Query: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR Sbjct: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 Query: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480 YGVGGQYEPHFDFSR K GNR+ATFLNYMSDVEAGGATVFPDLGAAIWPKK Sbjct: 421 YGVGGQYEPHFDFSRRPFDSGLK--TEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478 Query: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD Sbjct: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533 >gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2 precursor [Homo sapiens] Length = 533 Score = 1055 bits (2727), Expect = 0.0 Identities = 523/535 (97%), Positives = 524/535 (97%), Gaps = 2/535 (0%) Query: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS Sbjct: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 Query: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR Sbjct: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 Query: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480 YGVGGQYEPHFDFSR K GNR+ATFLNYMSDVEAGGATVFPDLGAAIWPKK Sbjct: 421 YGVGGQYEPHFDFSRRPFDSGLK--TEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478 Query: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD Sbjct: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533 >gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2 precursor [Homo sapiens] Length = 533 Score = 1055 bits (2727), Expect = 0.0 Identities = 523/535 (97%), Positives = 524/535 (97%), Gaps = 2/535 (0%) Query: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS Sbjct: 1 MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60 Query: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR Sbjct: 61 WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120 Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180 Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240 Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300 Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360 Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420 Query: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480 YGVGGQYEPHFDFSR K GNR+ATFLNYMSDVEAGGATVFPDLGAAIWPKK Sbjct: 421 YGVGGQYEPHFDFSRRPFDSGLK--TEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478 Query: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD Sbjct: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533 >gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1 precursor [Homo sapiens] Length = 534 Score = 712 bits (1838), Expect = 0.0 Identities = 339/537 (63%), Positives = 425/537 (79%), Gaps = 14/537 (2%) Query: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62 M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60 Query: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122 K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+ Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120 Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182 FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180 Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242 YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240 Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATPE--GIYERPVDYLPERDVYESLCRGEG 298 A GNL+YFE ++ +E++ K+ ++ + TP+ G+ VDYLPER YE LCRGEG Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297 Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358 +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357 Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418 P+L+RATV DP+TG LT A YRVSKS+WL ++PVV+R+N R+Q +TGL V TAE LQV Sbjct: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQV 417 Query: 419 ANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWP 478 ANYGVGGQYEPHFDF+R DE D FK LGTGNR+AT+L YMSDV AGGATVFP++GA++WP Sbjct: 418 ANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 477 Query: 479 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 KKGTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++ Sbjct: 478 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534 >gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2 precursor [Homo sapiens] Length = 534 Score = 702 bits (1812), Expect = 0.0 Identities = 334/537 (62%), Positives = 421/537 (78%), Gaps = 14/537 (2%) Query: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62 M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60 Query: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122 K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+ Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120 Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182 FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180 Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242 YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240 Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATPE--GIYERPVDYLPERDVYESLCRGEG 298 A GNL+YFE ++ +E++ K+ ++ + TP+ G+ VDYLPER YE LCRGEG Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297 Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358 +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357 Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418 P+L RAT+ +P TG L YR+SKS+WL ++PVV+R+N R+Q +TGL V TAE LQV Sbjct: 358 PRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQV 417 Query: 419 ANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWP 478 ANYGVGGQYEPHFDF+R DE D FK LGTGNR+AT+L YMSDV AGGATVFP++GA++WP Sbjct: 418 ANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 477 Query: 479 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 KKGTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++ Sbjct: 478 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534 >gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2 precursor [Homo sapiens] Length = 534 Score = 702 bits (1812), Expect = 0.0 Identities = 334/537 (62%), Positives = 421/537 (78%), Gaps = 14/537 (2%) Query: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62 M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60 Query: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122 K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+ Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120 Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182 FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180 Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242 YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240 Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATPE--GIYERPVDYLPERDVYESLCRGEG 298 A GNL+YFE ++ +E++ K+ ++ + TP+ G+ VDYLPER YE LCRGEG Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297 Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358 +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357 Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418 P+L RAT+ +P TG L YR+SKS+WL ++PVV+R+N R+Q +TGL V TAE LQV Sbjct: 358 PRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQV 417 Query: 419 ANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWP 478 ANYGVGGQYEPHFDF+R DE D FK LGTGNR+AT+L YMSDV AGGATVFP++GA++WP Sbjct: 418 ANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 477 Query: 479 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 KKGTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++ Sbjct: 478 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534 >gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3 precursor [Homo sapiens] Length = 516 Score = 663 bits (1710), Expect = 0.0 Identities = 322/537 (59%), Positives = 407/537 (75%), Gaps = 32/537 (5%) Query: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62 M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60 Query: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122 K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+ Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120 Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182 FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180 Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242 YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240 Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298 A GNL+YFE ++ +E++ K+ ++ + TP +G+ VDYLPER YE LCRGEG Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297 Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358 +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357 Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418 P+L+RATV DP+TG LT A YRVSKS+WL ++PVV+R+N R+Q +TGL V TAE LQ Sbjct: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ- 416 Query: 419 ANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWP 478 DE D FK LGTGNR+AT+L YMSDV AGGATVFP++GA++WP Sbjct: 417 -----------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 459 Query: 479 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 KKGTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++ Sbjct: 460 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516 >gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [Homo sapiens] Length = 544 Score = 329 bits (843), Expect = 4e-90 Identities = 197/539 (36%), Positives = 301/539 (55%), Gaps = 38/539 (7%) Query: 17 SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADA 76 + + + F+++ + + E+ L+ L+ Y+ EEA+L + + +K+ +L S Sbjct: 24 AAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTP- 82 Query: 77 EGYLAHPVNAYKLVKRLNTDWP-ALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKA 135 +A+P+ A+ L+KRL +DW + L ++ Q P ED GAA+A Sbjct: 83 ---VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARA 139 Query: 136 LMRLQDTYRLDPGTISRG-----------ELPGTKYQAMLSVDDCFGMGRSAYNEGDYYH 184 LMRLQD Y L+ ++RG +L K L+ DDCF +G+ AY+ GDYYH Sbjct: 140 LMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYH 199 Query: 185 TVLWMEQVLKQLDA--GEEATTTKSQV---LDYLSYAVFQLGDLHRALELTRRLLSLDPS 239 + W+E+ + GE T ++ + LD+L++A F+ G++ AL L+R L P Sbjct: 200 AIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPD 259 Query: 240 HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERP-VDYLPERDVYESLCRGEG 298 ++R N+ +E+LL E + E + +RP + +L RD YE LC+ G Sbjct: 260 NKRMARNVLKYERLLAESPNHVVA----------EAVIQRPNIPHLQTRDTYEGLCQTLG 309 Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358 + T + L+C Y + A LL+ P ++E P+I Y+D +SD E ++I+E+A+ Sbjct: 310 SQPTLYQIPSLYCSYETNSNA-YLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAE 368 Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKT--AELL 416 P L R+ V + + YR+SKS+WL++ DP + +N R+ +TGL V+ AE L Sbjct: 369 PWLQRSVVASGEKQLQV--EYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYL 426 Query: 417 QVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAI 476 QV NYG+GG YEPHFD + + ++ + +GNRVATF+ Y+S VEAGGAT F ++ Sbjct: 427 QVVNYGIGGHYEPHFDHATSPSSPLYR-MKSGNRVATFMIYLSSVEAGGATAFIYANLSV 485 Query: 477 WPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535 + A+FW+NL RSGEGD T HA CPVLVG KWV+NKW HE GQEF RPC S+ D Sbjct: 486 PVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED 544 >gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isoform a [Homo sapiens] Length = 502 Score = 71.6 bits (174), Expect = 2e-12 Identities = 55/187 (29%), Positives = 77/187 (41%), Gaps = 47/187 (25%) Query: 380 RVSKSSWLEEDDDP--VVARVNRRMQHITGLTVKTAEL---LQVANYGVGGQYEPHFDFS 434 R S +WL + + ++ + +R+ +T L+ + EL LQV YG GG Y H D Sbjct: 273 RNSHHTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSG 332 Query: 435 RNDERDTFKH----------LGTGNRVATFLNYMSDVEAGGATVFP-------------- 470 H T R T L Y+++V GG TVFP Sbjct: 333 PVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQ 392 Query: 471 ------------DLG-AAIWPKKGTAVFWYNLLRSGEG-----DYRTRHAACPVLVGCKW 512 D G + P++GTAVFWYN L G+G D + H C V G KW Sbjct: 393 DDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKW 452 Query: 513 VSNKWFH 519 ++N W + Sbjct: 453 IANNWIN 459 >gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isoform c [Homo sapiens] Length = 563 Score = 52.8 bits (125), Expect = 8e-07 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 32/99 (32%) Query: 453 TFLNYMSDVEAGGATVFP--------------------------DLG-AAIWPKKGTAVF 485 T L Y+++V GG TVFP D G + P++GTAVF Sbjct: 422 TVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVF 481 Query: 486 WYNLLRSGEG-----DYRTRHAACPVLVGCKWVSNKWFH 519 WYN L G+G D + H C V G KW++N W + Sbjct: 482 WYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWIN 520 Score = 33.1 bits (74), Expect = 0.65 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Query: 380 RVSKSSWLEEDDDP--VVARVNRRMQHITGLTVKTAEL---LQVANYGVGGQYEPHFD 432 R S +WL + + ++ + +R+ +T L+ + EL LQV YG GG Y H D Sbjct: 273 RNSHHTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVD 330 >gi|197313662 leprecan-like 1 isoform b [Homo sapiens] Length = 527 Score = 36.2 bits (82), Expect = 0.077 Identities = 16/46 (34%), Positives = 27/46 (58%) Query: 211 DYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEE 256 DYL +A +++G+ +ALE + L P E N+ Y+E LL++ Sbjct: 129 DYLQFAYYRVGEYVKALECAKAYLLCHPDDEDVLDNVDYYESLLDD 174 >gi|27764882 leprecan-like 1 isoform a [Homo sapiens] Length = 708 Score = 36.2 bits (82), Expect = 0.077 Identities = 16/46 (34%), Positives = 27/46 (58%) Query: 211 DYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEE 256 DYL +A +++G+ +ALE + L P E N+ Y+E LL++ Sbjct: 310 DYLQFAYYRVGEYVKALECAKAYLLCHPDDEDVLDNVDYYESLLDD 355 >gi|5454038 synaptonemal complex protein SC65 [Homo sapiens] Length = 437 Score = 33.9 bits (76), Expect = 0.38 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 4/70 (5%) Query: 212 YLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELA 271 YL YA+F+ L +A+ L +P HE L Y++ +L+ E + T+ E Sbjct: 147 YLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADE----SLTDLEAQ 202 Query: 272 TPEGIYERPV 281 E ++ R V Sbjct: 203 PYEAVFLRAV 212 >gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo sapiens] Length = 2139 Score = 32.7 bits (73), Expect = 0.85 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 33/166 (19%) Query: 237 DPSHERAGGNLR---YFEQLLEEEREKTLTNQTEA-ELATPEGIYERPVDYLPERDVYES 292 +P E A G+ Y LL ++ E L+ + E EG+YE+ V +RD+ E Sbjct: 594 EPQWELAPGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDIMEG 653 Query: 293 LCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIA--PFKEEDEWDSPHIVRYYDVMSDEEI 350 RLF R H G +PQ ++ F +D+ D P+ +S + I Sbjct: 654 ---------------RLFYR-HLGPHSPQSVMVQLAFHVQDDHDPPN-------LSKQHI 690 Query: 351 ERIK----EIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392 IK +I P+L T + + ++ + ++++D D Sbjct: 691 FTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSD 736 >gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo sapiens] Length = 2139 Score = 32.7 bits (73), Expect = 0.85 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 33/166 (19%) Query: 237 DPSHERAGGNLR---YFEQLLEEEREKTLTNQTEA-ELATPEGIYERPVDYLPERDVYES 292 +P E A G+ Y LL ++ E L+ + E EG+YE+ V +RD+ E Sbjct: 594 EPQWELAPGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDIMEG 653 Query: 293 LCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIA--PFKEEDEWDSPHIVRYYDVMSDEEI 350 RLF R H G +PQ ++ F +D+ D P+ +S + I Sbjct: 654 ---------------RLFYR-HLGPHSPQSVMVQLAFHVQDDHDPPN-------LSKQHI 690 Query: 351 ERIK----EIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392 IK +I P+L T + + ++ + ++++D D Sbjct: 691 FTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSD 736 >gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo sapiens] Length = 2139 Score = 32.7 bits (73), Expect = 0.85 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 33/166 (19%) Query: 237 DPSHERAGGNLR---YFEQLLEEEREKTLTNQTEA-ELATPEGIYERPVDYLPERDVYES 292 +P E A G+ Y LL ++ E L+ + E EG+YE+ V +RD+ E Sbjct: 594 EPQWELAPGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDIMEG 653 Query: 293 LCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIA--PFKEEDEWDSPHIVRYYDVMSDEEI 350 RLF R H G +PQ ++ F +D+ D P+ +S + I Sbjct: 654 ---------------RLFYR-HLGPHSPQSVMVQLAFHVQDDHDPPN-------LSKQHI 690 Query: 351 ERIK----EIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392 IK +I P+L T + + ++ + ++++D D Sbjct: 691 FTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSD 736 >gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sapiens] Length = 504 Score = 31.6 bits (70), Expect = 1.9 Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 10/101 (9%) Query: 191 QVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYF 250 + + L A + ++ +S +QLGD +L R L LD H+R + + Sbjct: 206 KAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQV 265 Query: 251 ----------EQLLEEEREKTLTNQTEAELATPEGIYERPV 281 E+L+ + R T++ E+ + T I E V Sbjct: 266 KKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTV 306 >gi|56676397 ankyrin repeat domain 11 [Homo sapiens] Length = 2663 Score = 30.4 bits (67), Expect = 4.2 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 5/48 (10%) Query: 327 FKEEDEWDSPHIVRYYDVMSDEE----IERIKEIAKPKLARATVRDPK 370 FK ED WDSP + Y D+ SD +E +KE +K + + R+ + Sbjct: 852 FKGEDSWDSP-VTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKR 898 >gi|29788755 SET binding factor 2 [Homo sapiens] Length = 1849 Score = 30.4 bits (67), Expect = 4.2 Identities = 34/167 (20%), Positives = 66/167 (39%), Gaps = 26/167 (15%) Query: 258 REKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHH-- 315 +EK +T Q + + EG+ + + ++ E V++ ++ + RY Sbjct: 952 KEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVEIFKKQLMKF--RYPQSI 1009 Query: 316 --------GNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVR 367 G PQ+++ KE++ + S ++ K K + R + Sbjct: 1010 FSTFAFAAGQTTPQIILPKQKEKNT--------SFRTFSKTIVKGAKRAGKMTIGRQYLL 1061 Query: 368 DPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAE 414 KTG T+ RV++ W E+DD V+ + T T+K +E Sbjct: 1062 KKKTG--TIVEERVNRPGWNEDDD----VSVSDESELPTSTTLKASE 1102 >gi|166795301 prenylcysteine oxidase 1 [Homo sapiens] Length = 505 Score = 30.0 bits (66), Expect = 5.5 Identities = 15/58 (25%), Positives = 29/58 (50%), Gaps = 3/58 (5%) Query: 416 LQVANYGVGGQYEPHF---DFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFP 470 + + G+GG ++ F ++ + D F+ G R+AT + + EAGG+ + P Sbjct: 37 IAIIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHP 94 >gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] Length = 839 Score = 30.0 bits (66), Expect = 5.5 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159 ++D+ L GFIA + PT D G + +M LQD +SR E Sbjct: 228 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 282 Query: 160 YQAMLSVDDCF 170 Q M +D C+ Sbjct: 283 -QRMNRLDQCY 292 >gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] Length = 815 Score = 30.0 bits (66), Expect = 5.5 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159 ++D+ L GFIA + PT D G + +M LQD +SR E Sbjct: 204 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 258 Query: 160 YQAMLSVDDCF 170 Q M +D C+ Sbjct: 259 -QRMNRLDQCY 268 >gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 30.0 bits (66), Expect = 5.5 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159 ++D+ L GFIA + PT D G + +M LQD +SR E Sbjct: 205 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 259 Query: 160 YQAMLSVDDCF 170 Q M +D C+ Sbjct: 260 -QRMNRLDQCY 269 >gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] Length = 866 Score = 30.0 bits (66), Expect = 5.5 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159 ++D+ L GFIA + PT D G + +M LQD +SR E Sbjct: 255 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 309 Query: 160 YQAMLSVDDCF 170 Q M +D C+ Sbjct: 310 -QRMNRLDQCY 319 >gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 30.0 bits (66), Expect = 5.5 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159 ++D+ L GFIA + PT D G + +M LQD +SR E Sbjct: 205 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 259 Query: 160 YQAMLSVDDCF 170 Q M +D C+ Sbjct: 260 -QRMNRLDQCY 269 >gi|163659918 sacsin [Homo sapiens] Length = 4579 Score = 29.6 bits (65), Expect = 7.2 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 3/69 (4%) Query: 192 VLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFE 251 VLK+LDA + K + L AV Q+ + +L ++ SL P+H+ A LR F Sbjct: 851 VLKKLDASIQHPLIKKYIHSPLPSAVLQIMEKMPLQKLCNQITSLLPTHKDA---LRKFL 907 Query: 252 QLLEEEREK 260 L + EK Sbjct: 908 ASLTDSSEK 916 >gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] Length = 1044 Score = 29.6 bits (65), Expect = 7.2 Identities = 34/164 (20%), Positives = 62/164 (37%), Gaps = 28/164 (17%) Query: 126 DEDEIGAAKALMRLQDTYRLDPGTISRGE-----------------------LPGTKYQA 162 +E E A + RL+D Y + + + E L G Q Sbjct: 877 EESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQK 936 Query: 163 MLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGD 222 +++D + +E V+ E + + EE K+++ + +L + Sbjct: 937 ERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEE 996 Query: 223 LHRALE--LTRR---LLSLDPSHERAGGNLRYFEQLLEEEREKT 261 +HR ++ L R+ + SL HE A + E+LLE+ R T Sbjct: 997 VHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEELLEQHRRPT 1040 >gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] Length = 1080 Score = 29.6 bits (65), Expect = 7.2 Identities = 34/164 (20%), Positives = 62/164 (37%), Gaps = 28/164 (17%) Query: 126 DEDEIGAAKALMRLQDTYRLDPGTISRGE-----------------------LPGTKYQA 162 +E E A + RL+D Y + + + E L G Q Sbjct: 913 EESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQK 972 Query: 163 MLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGD 222 +++D + +E V+ E + + EE K+++ + +L + Sbjct: 973 ERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEE 1032 Query: 223 LHRALE--LTRR---LLSLDPSHERAGGNLRYFEQLLEEEREKT 261 +HR ++ L R+ + SL HE A + E+LLE+ R T Sbjct: 1033 VHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEELLEQHRRPT 1076 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,300,619 Number of Sequences: 37866 Number of extensions: 891818 Number of successful extensions: 2338 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 15 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 2296 Number of HSP's gapped (non-prelim): 41 length of query: 535 length of database: 18,247,518 effective HSP length: 107 effective length of query: 428 effective length of database: 14,195,856 effective search space: 6075826368 effective search space used: 6075826368 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.