Search of human proteins with 4758506

Search of human proteins with 4758506

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758506 basic helix-loop-helix transcription factor HAND1
[Homo sapiens]
         (215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho...   452   e-127
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...   199   2e-51
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    76   2e-14
gi|148922889 scleraxis homolog B [Homo sapiens]                        72   3e-13
gi|186972126 scleraxis homolog A [Homo sapiens]                        72   3e-13
gi|239749439 PREDICTED: similar to transcription factor 23 [Homo...    70   2e-12
gi|239743573 PREDICTED: similar to transcription factor 23 [Homo...    70   2e-12
gi|239754900 PREDICTED: similar to transcription factor 23 [Homo...    68   7e-12
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    65   4e-11
gi|5031943 nescient helix loop helix 1 [Homo sapiens]                  63   2e-10
gi|4507741 twist [Homo sapiens]                                        60   1e-09
gi|17981708 twist homolog 2 [Homo sapiens]                             59   2e-09
gi|38202237 transcription factor 21 [Homo sapiens]                     59   3e-09
gi|38202239 transcription factor 21 [Homo sapiens]                     59   3e-09
gi|21553337 atonal homolog 7 [Homo sapiens]                            59   4e-09
gi|161484632 nescient helix loop helix 2 [Homo sapiens]                58   7e-09
gi|5031945 nescient helix loop helix 2 [Homo sapiens]                  58   7e-09
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    57   9e-09
gi|116805332 musculin [Homo sapiens]                                   57   1e-08
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]          56   2e-08
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          55   3e-08
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    53   2e-07
gi|14149724 mesoderm posterior 1 [Homo sapiens]                        53   2e-07
gi|116517330 factor in the germline alpha [Homo sapiens]               52   3e-07
gi|75677394 transcription factor 23 [Homo sapiens]                     52   3e-07
gi|38455396 neurogenin 1 [Homo sapiens]                                52   4e-07
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]                52   5e-07
gi|206597481 achaete-scute complex-like 4 [Homo sapiens]               51   6e-07
gi|239752994 PREDICTED: achaete-scute complex homolog 5 (Drosoph...    51   6e-07
gi|239747548 PREDICTED: achaete-scute complex homolog 5 (Drosoph...    51   6e-07

>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
           sapiens]
          Length = 215

 Score =  452 bits (1162), Expect = e-127
 Identities = 215/215 (100%), Positives = 215/215 (100%)

Query: 1   MNLVGSYAHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGG 60
           MNLVGSYAHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGG
Sbjct: 1   MNLVGSYAHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGG 60

Query: 61  PPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELREC 120
           PPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELREC
Sbjct: 61  PPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELREC 120

Query: 121 IPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRE 180
           IPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRE
Sbjct: 121 IPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRE 180

Query: 181 LQQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ 215
           LQQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ
Sbjct: 181 LQQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ 215


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score =  199 bits (505), Expect = 2e-51
 Identities = 120/223 (53%), Positives = 143/223 (64%), Gaps = 14/223 (6%)

Query: 1   MNLVGSYAHHHHHHHPHPAHPMLHEPFLFGPASRC-HQERPYFQSWLLS-PADAAPDFPA 58
           M+LVG + HH   HH                ASRC H+E PYF  WL+  P  + PD+  
Sbjct: 1   MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSM 60

Query: 59  G---GPPPAAAAAA---TAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINS 112
                P  A+ AA    + YG    PG  P  L   G R  +R+G+  +KERRRT+SINS
Sbjct: 61  ALSYSPEYASGAAGLDHSHYG-GVPPGAGPPGLG--GPRPVKRRGTANRKERRRTQSINS 117

Query: 113 AFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGG 172
           AFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMD+LAKD Q+G+ EAFKAE+KK D  
Sbjct: 118 AFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTD-V 176

Query: 173 RESKRKRELQQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ 215
           +E KRK+EL  +E     +   +K+ KGRTGWPQ VWALEL Q
Sbjct: 177 KEEKRKKEL--NEILKSTVSSNDKKTKGRTGWPQHVWALELKQ 217


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 52/120 (43%), Positives = 66/120 (55%), Gaps = 16/120 (13%)

Query: 73  GPDAR---PGQSPGRLEALGGRLG-----RRKGSGPKKERRRTESINSAFAELRECIPNV 124
           GP+A    PG   GR    GG  G     R++ +   +ER RT+S+N+AF  LR  IP  
Sbjct: 43  GPEAARRGPGPGGGRRAGGGGGAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTE 102

Query: 125 PADTKLSKIKTLRLATSYIAYLMDV--LAKDAQSGDP------EAFKAELKKADGGRESK 176
           P D KLSKI+TLRLA+SYIA+L +V  L   A  G P       A  A    ADGGR+ +
Sbjct: 103 PVDRKLSKIETLRLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGAVPAAADGGRQPR 162


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 42/95 (44%), Positives = 54/95 (56%), Gaps = 11/95 (11%)

Query: 64  AAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPN 123
           A    A   GP  RPG+ P           R++ +   +ER RT S+N+AF  LR  IP 
Sbjct: 56  AGGRRAGGGGPGGRPGREP-----------RQRHTANARERDRTNSVNTAFTALRTLIPT 104

Query: 124 VPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGD 158
            PAD KLSKI+TLRLA+SYI++L +VL      GD
Sbjct: 105 EPADRKLSKIETLRLASSYISHLGNVLLAGEACGD 139


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 42/95 (44%), Positives = 54/95 (56%), Gaps = 11/95 (11%)

Query: 64  AAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPN 123
           A    A   GP  RPG+ P           R++ +   +ER RT S+N+AF  LR  IP 
Sbjct: 56  AGGRRAGGGGPGGRPGREP-----------RQRHTANARERDRTNSVNTAFTALRTLIPT 104

Query: 124 VPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGD 158
            PAD KLSKI+TLRLA+SYI++L +VL      GD
Sbjct: 105 EPADRKLSKIETLRLASSYISHLGNVLLAGEACGD 139


>gi|239749439 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 46/108 (42%), Positives = 62/108 (57%), Gaps = 10/108 (9%)

Query: 57  PAGGPPPAAAAAA--TAYGPDARPGQSPGRLEALGGRLGRRKGSG------PKKERRRTE 108
           PAG P  A+A  A   A   D+RPG++       GG  G R GSG        +ER R +
Sbjct: 6   PAGSPLSASAEPAPLAAAIRDSRPGRTGPGPAGPGG--GSRSGSGRPAAANAARERSRVQ 63

Query: 109 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQS 156
           ++  AF EL+  +P+VP DTKLSK+  L LAT+YIA+L   L  DA++
Sbjct: 64  TLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEA 111


>gi|239743573 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 46/108 (42%), Positives = 62/108 (57%), Gaps = 10/108 (9%)

Query: 57  PAGGPPPAAAAAA--TAYGPDARPGQSPGRLEALGGRLGRRKGSG------PKKERRRTE 108
           PAG P  A+A  A   A   D+RPG++       GG  G R GSG        +ER R +
Sbjct: 6   PAGSPLSASAEPAPLAAAIRDSRPGRTGPGPAGPGG--GSRSGSGRPAAANAARERSRVQ 63

Query: 109 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQS 156
           ++  AF EL+  +P+VP DTKLSK+  L LAT+YIA+L   L  DA++
Sbjct: 64  TLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEA 111


>gi|239754900 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 67.8 bits (164), Expect = 7e-12
 Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 6/106 (5%)

Query: 57  PAGGPPPAAAAAA--TAYGPDARPGQSPGRLEALGGRL----GRRKGSGPKKERRRTESI 110
           PAG P  A+A  A   A   D RPG++      LGG      GR       +ER R +++
Sbjct: 6   PAGSPLSASAEPAPLAAAIRDXRPGRTGPGPAGLGGGSCSGSGRPAAENAARERSRVQTL 65

Query: 111 NSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQS 156
             AF E++  +P+VP DTKLSK+  L LAT+YIA+L   L  DA++
Sbjct: 66  RHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEA 111


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 60/182 (32%), Positives = 81/182 (44%), Gaps = 27/182 (14%)

Query: 33  SRCHQERPYFQSWLLSPADAAPD--FPAGGPPPA---------AAAAATAYGPDARPGQS 81
           +R  + R   Q    +P +  PD   P  GP PA         AAA A   G   RPG S
Sbjct: 5   NRPPRRRAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRPGPS 64

Query: 82  PGRLEALGGRLG---RRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRL 138
                  GGR     +R+    ++ER+R   +N+AF  LRE IP+V AD KLSKI+TL L
Sbjct: 65  -----GPGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTL 119

Query: 139 ATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRELQQHEGFPPALGPVEKRI 198
           A +YI  L   +   + S         L   +G      +   QQ +    ALG  E + 
Sbjct: 120 AKNYIKSLTATILTMSSS--------RLPGLEGPGPKLYQHYQQQQQVAGGALGATEAQP 171

Query: 199 KG 200
           +G
Sbjct: 172 QG 173


>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
          Length = 133

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 47/109 (43%), Positives = 57/109 (52%), Gaps = 17/109 (15%)

Query: 52  AAPDFPAGGPPPAAAAAATAYGPDARPGQSPGR--LEALGGRLGRRKGSGPKK------- 102
           A PD    G  P       A GP+  PG+ PGR  L+ L     RR+     K       
Sbjct: 30  AGPD----GAGPGGPGGGQARGPE--PGE-PGRKDLQHLSREERRRRRRATAKYRTAHAT 82

Query: 103 -ERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVL 150
            ER R E+ N AFAELR+ +P +P D KLSKI+ LRLA  YI+YL  VL
Sbjct: 83  RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 45/120 (37%), Positives = 56/120 (46%), Gaps = 20/120 (16%)

Query: 49  PADAAPDFPAGGPPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPK------- 101
           P  AA     GG  P + A        A  G   G     GG  G   G G         
Sbjct: 52  PGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGA----GGGGGSSSGGGSPQSYEELQ 107

Query: 102 --------KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153
                   +ER+RT+S+N AFA LR+ IP +P+D KLSKI+TL+LA  YI +L  VL  D
Sbjct: 108 TQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 166


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 30/52 (57%), Positives = 40/52 (76%), Gaps = 1/52 (1%)

Query: 102 KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153
           +ER+RT+S+N AFA LR+ IP +P+D KLSKI+TL+LA  YI +L  VL  D
Sbjct: 74  RERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 124


>gi|38202237 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 28/59 (47%), Positives = 41/59 (69%)

Query: 95  RKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153
           ++ +   +ER R   ++ AF+ L+  +P VP DTKLSK+ TLRLA+SYIA+L  +LA D
Sbjct: 80  QRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILAND 138


>gi|38202239 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 28/59 (47%), Positives = 41/59 (69%)

Query: 95  RKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153
           ++ +   +ER R   ++ AF+ L+  +P VP DTKLSK+ TLRLA+SYIA+L  +LA D
Sbjct: 80  QRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILAND 138


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 39/102 (38%), Positives = 55/102 (53%), Gaps = 5/102 (4%)

Query: 57  PAGGPPPAAAAAATAYGPD-ARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFA 115
           P+G P  A  A   A G + A      GRLE+      RR+ +   +ERRR + +N+AF 
Sbjct: 6   PSGPPAGARVAPPCAGGTECAGTCAGAGRLESAA----RRRLAANARERRRMQGLNTAFD 61

Query: 116 ELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSG 157
            LR  +P    D KLSK +TL++A SYI  L  +LA+  + G
Sbjct: 62  RLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFG 103


>gi|161484632 nescient helix loop helix 2 [Homo sapiens]
          Length = 135

 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 29/49 (59%), Positives = 36/49 (73%)

Query: 102 KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVL 150
           +ER R E+ N AFAELR+ +P +P D KLSKI+ LRLA  YI+YL  VL
Sbjct: 85  RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 133


>gi|5031945 nescient helix loop helix 2 [Homo sapiens]
          Length = 135

 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 29/49 (59%), Positives = 36/49 (73%)

Query: 102 KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVL 150
           +ER R E+ N AFAELR+ +P +P D KLSKI+ LRLA  YI+YL  VL
Sbjct: 85  RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 133


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 57.4 bits (137), Expect = 9e-09
 Identities = 39/110 (35%), Positives = 53/110 (48%), Gaps = 12/110 (10%)

Query: 56  FPAGGPPPAAA---AAATAYGPDARPGQSPGRLEALGGR---------LGRRKGSGPKKE 103
           +  G PP   A   A A    P AR     G   A   R         L + + +   +E
Sbjct: 113 YSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRE 172

Query: 104 RRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153
           RRR +SIN AF  LR  IP +P + +LSK+ TLRLA  YI +L +++  D
Sbjct: 173 RRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 5/94 (5%)

Query: 63  PAAAAAATAYGPDARPGQSPGRLEALGGRLG---RRKGSGPKKERRRTESINSAFAELRE 119
           P  A    A G     G+ P  L A G        ++ +   +ER R   ++ AF+ L+ 
Sbjct: 75  PRVAGGGGAGGSAGGGGKKP--LPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKT 132

Query: 120 CIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153
            +P VP DTKLSK+ TLRLA+SYIA+L  +L +D
Sbjct: 133 SLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQED 166


>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
          Length = 108

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 28/53 (52%), Positives = 39/53 (73%)

Query: 102 KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDA 154
           +ER R +++NSAFA+LR+ IP  P D KLSK +TLRLA  YI +L+ VL + +
Sbjct: 10  RERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQS 62


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 47/134 (35%), Positives = 62/134 (46%), Gaps = 18/134 (13%)

Query: 46  LLSPADAAPDFPAGG-----PPPAAAAAATAYG-PDARP----------GQSPGRLEALG 89
           L  PA AAP  P          P A+  +  +G PDA P            SP  +E   
Sbjct: 121 LSPPALAAPAAPGRALLYSLSQPLASLGSGFFGEPDAFPMFTTNNRVKRRPSPYEMEITD 180

Query: 90  GRLGR--RKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLM 147
           G   +  R+     +ER R +++N AFAELR+ IP  P D KLSK + LRLA  YI +L 
Sbjct: 181 GPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLA 240

Query: 148 DVLAKDAQSGDPEA 161
            +L    + G   A
Sbjct: 241 KLLNDQEEEGTQRA 254


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 26/53 (49%), Positives = 36/53 (67%)

Query: 102 KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDA 154
           +ER R +++N AFAELR+ +P  P D KLSK + LRLA  YI +L+ +L   A
Sbjct: 158 RERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQA 210


>gi|14149724 mesoderm posterior 1 [Homo sapiens]
          Length = 268

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 48/146 (32%), Positives = 66/146 (45%), Gaps = 10/146 (6%)

Query: 18  PAHPMLHEPFL----FGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYG 73
           P  P L E ++    +GP  R           L+S  D+    PA  P  + A   T   
Sbjct: 4   PLCPPLSESWMLSAAWGPTRRPPPSDKDCGRSLVSSPDSWGSTPADSPVASPARPGTLRD 63

Query: 74  PDARPGQSPGRLEALGGRLGR-RKGSGPKKERRRTESINSAFAELRECIPN--VPADTKL 130
           P A    S GR  A   RLG  ++ S  ++E+ R  ++  A  ELR  +P    PA   L
Sbjct: 64  PRA---PSVGRRGARSSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPSVAPAGQSL 120

Query: 131 SKIKTLRLATSYIAYLMDVLAKDAQS 156
           +KI+TLRLA  YI +L  VL    +S
Sbjct: 121 TKIETLRLAIRYIGHLSAVLGLSEES 146


>gi|116517330 factor in the germline alpha [Homo sapiens]
          Length = 219

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)

Query: 102 KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVL--AKDAQSGDP 159
           KER R +++N  FA L+  +P +P   K SK+  L+ AT YI  L D+L  AKD++  DP
Sbjct: 73  KERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDP 132

Query: 160 EAFKAELKKADGGRESKRK--RELQQH 184
           +        ++    S R+  R + QH
Sbjct: 133 DEQSYSNNSSESHTSSARQLSRNITQH 159


>gi|75677394 transcription factor 23 [Homo sapiens]
          Length = 214

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 34/80 (42%), Positives = 43/80 (53%), Gaps = 4/80 (5%)

Query: 76  ARPGQSPGRLEALGGRLGRRKGS--GPKKERRRTESINSAFAELRECIPNVPADTKLSKI 133
           A PG  P    A G  LGR + S     +ER R  ++  AF  L+  +P VP DTKLSK+
Sbjct: 58  ATPG--PRGTRAGGLALGRSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKL 115

Query: 134 KTLRLATSYIAYLMDVLAKD 153
             L LA SYIA+L   L  +
Sbjct: 116 DVLVLAASYIAHLTRTLGHE 135


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 32/75 (42%), Positives = 45/75 (60%), Gaps = 1/75 (1%)

Query: 77  RPGQSPGRLEALGGRLGR-RKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKT 135
           R G++  R EAL   L R R+     +ER R  ++N+A   LR  +P+ P DTKL+KI+T
Sbjct: 74  RRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIET 133

Query: 136 LRLATSYIAYLMDVL 150
           LR A +YI  L + L
Sbjct: 134 LRFAYNYIWALAETL 148


>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
          Length = 397

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 36/110 (32%), Positives = 52/110 (47%), Gaps = 10/110 (9%)

Query: 49  PADAAPDFPAGGPPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTE 108
           P D A   P   PP  ++ AA A     R  ++        G  G ++ S  ++E+ R  
Sbjct: 44  PCDGARGLPQPQPPSCSSRAAEAAATTPRRART--------GPAGGQRQSASEREKLRMR 95

Query: 109 SINSAFAELRECIPN--VPADTKLSKIKTLRLATSYIAYLMDVLAKDAQS 156
           ++  A  ELR  +P    PA   L+KI+TLRLA  YI +L  VL    +S
Sbjct: 96  TLARALHELRRFLPPSLAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEES 145


>gi|206597481 achaete-scute complex-like 4 [Homo sapiens]
          Length = 173

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 25/78 (32%), Positives = 45/78 (57%)

Query: 101 KKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPE 160
           ++ER+R   +N  +A LR+ +P   AD +LSK++TLR A  YI +L ++L + A   +  
Sbjct: 80  ERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGA 139

Query: 161 AFKAELKKADGGRESKRK 178
           A     ++A+   + + K
Sbjct: 140 AGAVPQRRAECNSDGESK 157


>gi|239752994 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 42/144 (29%), Positives = 63/144 (43%), Gaps = 29/144 (20%)

Query: 18  PAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYGPDAR 77
           PA P+ + PFL  P      E PY+ ++    A   P  P  G          A+G    
Sbjct: 143 PAEPLGNVPFLLYPGPA---EPPYYDAY----AGVFPYVPFPG----------AFGVYEY 185

Query: 78  PGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLR 137
           P + P  ++    R           ER+R + +N  +A LR  +P   A+ +LSK++TLR
Sbjct: 186 PFE-PAFIQKRNER-----------ERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLR 233

Query: 138 LATSYIAYLMDVLAKDAQSGDPEA 161
            A  YI YL ++L+       P A
Sbjct: 234 AAIRYIKYLQELLSSAPDGSTPPA 257


>gi|239747548 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 42/144 (29%), Positives = 63/144 (43%), Gaps = 29/144 (20%)

Query: 18  PAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYGPDAR 77
           PA P+ + PFL  P      E PY+ ++    A   P  P  G          A+G    
Sbjct: 143 PAEPLGNVPFLLYPGPA---EPPYYDAY----AGVFPYVPFPG----------AFGVYEY 185

Query: 78  PGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLR 137
           P + P  ++    R           ER+R + +N  +A LR  +P   A+ +LSK++TLR
Sbjct: 186 PFE-PAFIQKRNER-----------ERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLR 233

Query: 138 LATSYIAYLMDVLAKDAQSGDPEA 161
            A  YI YL ++L+       P A
Sbjct: 234 AAIRYIKYLQELLSSAPDGSTPPA 257


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,658,426
Number of Sequences: 37866
Number of extensions: 599240
Number of successful extensions: 6268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 204
Number of HSP's that attempted gapping in prelim test: 4576
Number of HSP's gapped (non-prelim): 1167
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.