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Search of human proteins with 4758332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758332 acyl-CoA synthetase long-chain family member 4
isoform 1 [Homo sapiens]
(670 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 1365 0.0
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 1365 0.0
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo... 942 0.0
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo... 942 0.0
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 315 1e-85
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 315 1e-85
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 315 1e-85
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 310 2e-84
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 306 5e-83
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 305 7e-83
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 149 6e-36
gi|27477105 lipidosin [Homo sapiens] 135 2e-31
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 63 1e-09
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 63 1e-09
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 59 1e-08
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 47 7e-05
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 45 3e-04
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 41 0.004
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 40 0.005
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 40 0.005
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 39 0.020
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 39 0.020
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 39 0.020
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 38 0.035
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 36 0.10
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 34 0.50
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 33 0.65
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 33 1.1
gi|62955829 hypothetical protein LOC90871 [Homo sapiens] 32 1.9
gi|227499621 solute carrier family 27 (fatty acid transporter), ... 32 2.5
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 1365 bits (3533), Expect = 0.0
Identities = 670/670 (100%), Positives = 670/670 (100%)
Query: 1 MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI 60
MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI
Sbjct: 1 MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI 60
Query: 61 LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA 120
LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA
Sbjct: 61 LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA 120
Query: 121 EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC 180
EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC
Sbjct: 121 EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC 180
Query: 181 VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS 240
VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS
Sbjct: 181 VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS 240
Query: 241 TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG 300
TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG
Sbjct: 241 TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG 300
Query: 301 YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK 360
YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK
Sbjct: 301 YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK 360
Query: 361 IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP 420
IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP
Sbjct: 361 IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP 420
Query: 421 IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI 480
IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI
Sbjct: 421 IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI 480
Query: 481 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 540
GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE
Sbjct: 481 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 540
Query: 541 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 600
YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN
Sbjct: 541 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 600
Query: 601 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 660
NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL
Sbjct: 601 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 660
Query: 661 KDIERMYGGK 670
KDIERMYGGK
Sbjct: 661 KDIERMYGGK 670
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 1365 bits (3533), Expect = 0.0
Identities = 670/670 (100%), Positives = 670/670 (100%)
Query: 1 MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI 60
MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI
Sbjct: 42 MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI 101
Query: 61 LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA 120
LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA
Sbjct: 102 LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA 161
Query: 121 EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC 180
EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC
Sbjct: 162 EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC 221
Query: 181 VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS 240
VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS
Sbjct: 222 VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS 281
Query: 241 TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG 300
TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG
Sbjct: 282 TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG 341
Query: 301 YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK 360
YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK
Sbjct: 342 YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK 401
Query: 361 IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP 420
IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP
Sbjct: 402 IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP 461
Query: 421 IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI 480
IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI
Sbjct: 462 IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI 521
Query: 481 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 540
GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE
Sbjct: 522 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 581
Query: 541 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 600
YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN
Sbjct: 582 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 641
Query: 601 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 660
NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL
Sbjct: 642 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 701
Query: 661 KDIERMYGGK 670
KDIERMYGGK
Sbjct: 702 KDIERMYGGK 711
>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 942 bits (2435), Expect = 0.0
Identities = 451/669 (67%), Positives = 545/669 (81%)
Query: 2 AKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREIL 61
+ RIKAKP + KP S YRSV D LA + PG DTLDK+F +A +KF K LGTRE+L
Sbjct: 52 SNRIKAKPVNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVL 111
Query: 62 SEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAE 121
+EE+E+QPNGK+FKK+ILG Y W++Y +V R NFG+GL LG KPK IAIFCETRAE
Sbjct: 112 NEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAE 171
Query: 122 WMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV 181
WMIAAQ CF YNF LVTLYATLG A+VH LNE+E + +ITS ELL++KLK + + +
Sbjct: 172 WMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRL 231
Query: 182 KHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGST 241
+HII VD K +E+P+G +H+M +VE LG+ P S+P PSD+A++MYTSGST
Sbjct: 232 RHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGST 291
Query: 242 GRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY 301
G PKGVM+ HSN+IAG+TG ERIP LG +D YIGYLPLAHVLEL+AE+ C ++GCRIGY
Sbjct: 292 GLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY 351
Query: 302 SSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKI 361
SSP TL+DQSSKIKKGSKGD ++LKPTLMAAVPEIMDRIYKNVM+KV EM+ Q+ LF +
Sbjct: 352 SSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFIL 411
Query: 362 GYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 421
Y+YK+EQI KG + PLC+ +F+KV++LLGGN+R++L GGAPLS T RFMN+CFCCP+
Sbjct: 412 AYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPV 471
Query: 422 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIG 481
GQGYGLTES GAGT++EV DY TGRVGAPL+CCEIKLK+W+EGGY DKP+PRGEI+IG
Sbjct: 472 GQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIG 531
Query: 482 GQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEY 541
GQ+++MGY+KNE KT D+ DENGQRW CTGDIGEF PDGCL+IIDRKKDLVKLQAGEY
Sbjct: 532 GQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEY 591
Query: 542 VSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNN 601
VSLGKVEAALKN PL+DNICA+A S SYVI FVVPNQK LT LA++KG++GTW ++CN+
Sbjct: 592 VSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNS 651
Query: 602 PAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLK 661
ME E+LK + EAA + LE+FEIP+K+RLSPEPWTPETGLVTDAFKLKRKEL+ HY
Sbjct: 652 CEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQA 711
Query: 662 DIERMYGGK 670
DIERMYG K
Sbjct: 712 DIERMYGRK 720
>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 942 bits (2435), Expect = 0.0
Identities = 451/669 (67%), Positives = 545/669 (81%)
Query: 2 AKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREIL 61
+ RIKAKP + KP S YRSV D LA + PG DTLDK+F +A +KF K LGTRE+L
Sbjct: 52 SNRIKAKPVNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVL 111
Query: 62 SEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAE 121
+EE+E+QPNGK+FKK+ILG Y W++Y +V R NFG+GL LG KPK IAIFCETRAE
Sbjct: 112 NEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAE 171
Query: 122 WMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV 181
WMIAAQ CF YNF LVTLYATLG A+VH LNE+E + +ITS ELL++KLK + + +
Sbjct: 172 WMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRL 231
Query: 182 KHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGST 241
+HII VD K +E+P+G +H+M +VE LG+ P S+P PSD+A++MYTSGST
Sbjct: 232 RHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGST 291
Query: 242 GRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY 301
G PKGVM+ HSN+IAG+TG ERIP LG +D YIGYLPLAHVLEL+AE+ C ++GCRIGY
Sbjct: 292 GLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY 351
Query: 302 SSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKI 361
SSP TL+DQSSKIKKGSKGD ++LKPTLMAAVPEIMDRIYKNVM+KV EM+ Q+ LF +
Sbjct: 352 SSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFIL 411
Query: 362 GYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 421
Y+YK+EQI KG + PLC+ +F+KV++LLGGN+R++L GGAPLS T RFMN+CFCCP+
Sbjct: 412 AYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPV 471
Query: 422 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIG 481
GQGYGLTES GAGT++EV DY TGRVGAPL+CCEIKLK+W+EGGY DKP+PRGEI+IG
Sbjct: 472 GQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIG 531
Query: 482 GQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEY 541
GQ+++MGY+KNE KT D+ DENGQRW CTGDIGEF PDGCL+IIDRKKDLVKLQAGEY
Sbjct: 532 GQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEY 591
Query: 542 VSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNN 601
VSLGKVEAALKN PL+DNICA+A S SYVI FVVPNQK LT LA++KG++GTW ++CN+
Sbjct: 592 VSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNS 651
Query: 602 PAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLK 661
ME E+LK + EAA + LE+FEIP+K+RLSPEPWTPETGLVTDAFKLKRKEL+ HY
Sbjct: 652 CEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQA 711
Query: 662 DIERMYGGK 670
DIERMYG K
Sbjct: 712 DIERMYGRK 720
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 315 bits (806), Expect = 1e-85
Identities = 203/607 (33%), Positives = 322/607 (53%), Gaps = 52/607 (8%)
Query: 82 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Y+W++Y +V+ R GS L G K P + IF + R EW+I+ C+ Y+ V L
Sbjct: 103 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 162
Query: 140 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV--------KHIIYVD--N 189
Y TLG EA+VH +N+++ + +I + AL+ I V K II +D +
Sbjct: 163 YDTLGPEAIVHIVNKADIAMVICDTP------QKALVLIGNVEKGFTPSLKVIILMDPFD 216
Query: 190 KAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 249
+ + G EI S+ E LG +PPS P D++++ +TSG+TG PKG M+
Sbjct: 217 DDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPS---PEDLSVICFTSGTTGDPKGAMI 273
Query: 250 HHSNLIAGMTG--QC-ERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 304
H N+++ +C E P D I YLPLAH+ E + ++ G R+G+
Sbjct: 274 THQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 333
Query: 305 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 364
L+D D LKPTL AVP +++RIY V ++ + ++K L K+
Sbjct: 334 RLLAD-----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP--LKKFLLKLAVS 380
Query: 365 YKLEQIKKG---YDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 421
K ++++KG +D+ + L+F K++ LGG VR++++G AP+S F C +
Sbjct: 381 SKFKELQKGIIRHDS-FWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQV 439
Query: 422 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGY-TINDKPNPRGEIVI 480
+ YG TE G T T D+T+G VG PL C +KL+D + Y T+N++ GE+ I
Sbjct: 440 YEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNE----GEVCI 495
Query: 481 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 540
G N+ GY K+ EKT E ++D +G W TGDIG + P+G L+IIDRKK++ KL GE
Sbjct: 496 KGTNVFKGYLKDPEKTQE--ALDSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGE 551
Query: 541 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 600
Y++ K+E + I +S +S ++ VVP+ L A + GV+G++ ++C
Sbjct: 552 YIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQ 611
Query: 601 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 660
N + IL+++++ L+ FE + L PEP++ E GL+T K KR EL ++
Sbjct: 612 NQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFR 671
Query: 661 KDIERMY 667
I+ +Y
Sbjct: 672 TQIDSLY 678
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 315 bits (806), Expect = 1e-85
Identities = 203/607 (33%), Positives = 322/607 (53%), Gaps = 52/607 (8%)
Query: 82 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Y+W++Y +V+ R GS L G K P + IF + R EW+I+ C+ Y+ V L
Sbjct: 103 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 162
Query: 140 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV--------KHIIYVD--N 189
Y TLG EA+VH +N+++ + +I + AL+ I V K II +D +
Sbjct: 163 YDTLGPEAIVHIVNKADIAMVICDTP------QKALVLIGNVEKGFTPSLKVIILMDPFD 216
Query: 190 KAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 249
+ + G EI S+ E LG +PPS P D++++ +TSG+TG PKG M+
Sbjct: 217 DDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPS---PEDLSVICFTSGTTGDPKGAMI 273
Query: 250 HHSNLIAGMTG--QC-ERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 304
H N+++ +C E P D I YLPLAH+ E + ++ G R+G+
Sbjct: 274 THQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 333
Query: 305 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 364
L+D D LKPTL AVP +++RIY V ++ + ++K L K+
Sbjct: 334 RLLAD-----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP--LKKFLLKLAVS 380
Query: 365 YKLEQIKKG---YDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 421
K ++++KG +D+ + L+F K++ LGG VR++++G AP+S F C +
Sbjct: 381 SKFKELQKGIIRHDS-FWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQV 439
Query: 422 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGY-TINDKPNPRGEIVI 480
+ YG TE G T T D+T+G VG PL C +KL+D + Y T+N++ GE+ I
Sbjct: 440 YEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNE----GEVCI 495
Query: 481 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 540
G N+ GY K+ EKT E ++D +G W TGDIG + P+G L+IIDRKK++ KL GE
Sbjct: 496 KGTNVFKGYLKDPEKTQE--ALDSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGE 551
Query: 541 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 600
Y++ K+E + I +S +S ++ VVP+ L A + GV+G++ ++C
Sbjct: 552 YIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQ 611
Query: 601 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 660
N + IL+++++ L+ FE + L PEP++ E GL+T K KR EL ++
Sbjct: 612 NQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFR 671
Query: 661 KDIERMY 667
I+ +Y
Sbjct: 672 TQIDSLY 678
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 315 bits (806), Expect = 1e-85
Identities = 203/607 (33%), Positives = 322/607 (53%), Gaps = 52/607 (8%)
Query: 82 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Y+W++Y +V+ R GS L G K P + IF + R EW+I+ C+ Y+ V L
Sbjct: 159 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 218
Query: 140 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV--------KHIIYVD--N 189
Y TLG EA+VH +N+++ + +I + AL+ I V K II +D +
Sbjct: 219 YDTLGPEAIVHIVNKADIAMVICDTP------QKALVLIGNVEKGFTPSLKVIILMDPFD 272
Query: 190 KAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 249
+ + G EI S+ E LG +PPS P D++++ +TSG+TG PKG M+
Sbjct: 273 DDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPS---PEDLSVICFTSGTTGDPKGAMI 329
Query: 250 HHSNLIAGMTG--QC-ERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 304
H N+++ +C E P D I YLPLAH+ E + ++ G R+G+
Sbjct: 330 THQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 389
Query: 305 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 364
L+D D LKPTL AVP +++RIY V ++ + ++K L K+
Sbjct: 390 RLLAD-----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP--LKKFLLKLAVS 436
Query: 365 YKLEQIKKG---YDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 421
K ++++KG +D+ + L+F K++ LGG VR++++G AP+S F C +
Sbjct: 437 SKFKELQKGIIRHDS-FWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQV 495
Query: 422 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGY-TINDKPNPRGEIVI 480
+ YG TE G T T D+T+G VG PL C +KL+D + Y T+N++ GE+ I
Sbjct: 496 YEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNE----GEVCI 551
Query: 481 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 540
G N+ GY K+ EKT E ++D +G W TGDIG + P+G L+IIDRKK++ KL GE
Sbjct: 552 KGTNVFKGYLKDPEKTQE--ALDSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGE 607
Query: 541 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 600
Y++ K+E + I +S +S ++ VVP+ L A + GV+G++ ++C
Sbjct: 608 YIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQ 667
Query: 601 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 660
N + IL+++++ L+ FE + L PEP++ E GL+T K KR EL ++
Sbjct: 668 NQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFR 727
Query: 661 KDIERMY 667
I+ +Y
Sbjct: 728 TQIDSLY 734
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 310 bits (795), Expect = 2e-84
Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%)
Query: 82 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Y+W++Y +V GS L G K P I IF + R EW+I Q CF Y+ +V L
Sbjct: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
Query: 140 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 191
Y TLG EA+ + +N++E S + +E +E+KL I +K I+ +D
Sbjct: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231
Query: 192 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 249
E + G E+ SM+++E+LG P P P D+A++ +TSG+TG PKG M+
Sbjct: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288
Query: 250 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 304
H N+++ + E P DT I +LPLAH+ E E +G +IG+
Sbjct: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348
Query: 305 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 364
L D D VL+PT+ VP +++R++ + Q +++ L
Sbjct: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395
Query: 365 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 422
K +++ G + L + L+F KV++ LGG VR+M++G AP+S F+ C
Sbjct: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455
Query: 423 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 482
+GYG TE +T D+T G VGAP+ C IKL D +E Y + GE+ + G
Sbjct: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512
Query: 483 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 542
N+ GY K+ KTAE ++D++G W TGDIG++ P+G L+IIDRKK + KL GEY+
Sbjct: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568
Query: 543 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 602
+ K+E + + +S Q+++I+ VVP+ + L AQ++G EG++ ++C N
Sbjct: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628
Query: 603 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 662
++ IL+++ L+ FE + L PE ++ + GL+T K KR ELRN++
Sbjct: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688
Query: 663 IERMY 667
I+ +Y
Sbjct: 689 IDDLY 693
>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
a [Homo sapiens]
Length = 722
Score = 306 bits (783), Expect = 5e-83
Identities = 200/604 (33%), Positives = 313/604 (51%), Gaps = 46/604 (7%)
Query: 82 YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Y+W++Y EV R GSGL K I +F + R EW+I C+ Y+ +V L
Sbjct: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Query: 140 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 192
Y TLG A+ + +N ++ S +I +V LLE + + +K II +D +A+
Sbjct: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259
Query: 193 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 252
+ G I SMQ+VE+ G +PP P D++IV +TSG+TG PKG M+ H
Sbjct: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316
Query: 253 NLIAGMTG-----QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPL 305
N++A +G + + P D +I YLPLAH+ E + + +G R+G+
Sbjct: 317 NVVADFSGFLKVTESQWAPTCA--DVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIR 374
Query: 306 TLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDY 365
LSD D L PT+ VP +++R+Y + S Q +++ L +
Sbjct: 375 LLSD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKR 421
Query: 366 KLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQ 423
K +++ G + + + L F K++A LGG VRM+++G AP SP F+ C + +
Sbjct: 422 KQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE 481
Query: 424 GYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQ 483
GYG TE T T D+T+G VGAPL C IKL D +E Y GEI + G
Sbjct: 482 GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGP 538
Query: 484 NISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVS 543
N+ GY K+ ++T E ++D +G W TGDIG++ P G L+IIDRKK + KL GEYV+
Sbjct: 539 NVFKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVA 594
Query: 544 LGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPA 603
K+E + I S +++++ VVP+ + + AQ++G+EGT+ D+C N
Sbjct: 595 PEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKD 654
Query: 604 MEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDI 663
++ IL+++ L FE + + + ++ + GL+T K KR ELR ++ K I
Sbjct: 655 LKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQI 714
Query: 664 ERMY 667
E +Y
Sbjct: 715 EELY 718
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 305 bits (782), Expect = 7e-83
Identities = 199/602 (33%), Positives = 312/602 (51%), Gaps = 42/602 (6%)
Query: 82 YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Y+W++Y EV R GSGL K I +F + R EW+I C+ Y+ +V L
Sbjct: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Query: 140 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 192
Y TLG A+ + +N ++ S +I +V LLE + + +K II +D +A+
Sbjct: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259
Query: 193 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 252
+ G I SMQ+VE+ G +PP P D++IV +TSG+TG PKG M+ H
Sbjct: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316
Query: 253 NLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPLTL 307
N++A +G E++ D I +LPLAH+ E + + +G R+G+ L
Sbjct: 317 NVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLL 376
Query: 308 SDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKL 367
SD D L PT+ VP +++R+Y + S Q +++ L + K
Sbjct: 377 SD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKRKQ 423
Query: 368 EQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGY 425
+++ G + + + L F K++A LGG VRM+++G AP SP F+ C + +GY
Sbjct: 424 AEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGY 483
Query: 426 GLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNI 485
G TE T T D+T+G VGAPL C IKL D +E Y GEI + G N+
Sbjct: 484 GQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGPNV 540
Query: 486 SMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLG 545
GY K+ ++T E ++D +G W TGDIG++ P G L+IIDRKK + KL GEYV+
Sbjct: 541 FKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPE 596
Query: 546 KVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAME 605
K+E + I S +++++ VVP+ + + AQ++G+EGT+ D+C N ++
Sbjct: 597 KIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLK 656
Query: 606 AEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIER 665
IL+++ L FE + + + ++ + GL+T K KR ELR ++ K IE
Sbjct: 657 KAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEE 716
Query: 666 MY 667
+Y
Sbjct: 717 LY 718
>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
Length = 666
Score = 149 bits (377), Expect = 6e-36
Identities = 168/669 (25%), Positives = 289/669 (43%), Gaps = 93/669 (13%)
Query: 37 TLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNN 96
T+ + F +V++FG +L ++ NGK ++ L + Y E R+
Sbjct: 52 TIPEFFRESVNRFGTYPALASK-----------NGKKWEIL-----NFNQYYEACRKA-- 93
Query: 97 FGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESE 156
L LGL+ + + I AEW I A V +YAT E + + ++
Sbjct: 94 -AKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAK 152
Query: 157 ASYLIT-SVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSN 215
+ L+ + + L+ L + +K II + + ++S ELG +
Sbjct: 153 VNILLVENDQQLQKILSIPQSSLEPLKAIIQY------RLPMKKNNNLYSWDDFMELGRS 206
Query: 216 PENLGIPP--SRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL--IAGMTGQCERIPGLGPK 271
+ + + A+++YTSG+TG PKGVM+ H N+ IAG + ++
Sbjct: 207 IPDTQLEQVIESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKL--TDKH 264
Query: 272 DTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMA 331
+T + YLPL+H+ A++ +IG LT Q+ +K +KPT+
Sbjct: 265 ETVVSYLPLSHI---AAQMMDIWVPIKIG---ALTYFAQADALKGTLVSTLKEVKPTVFI 318
Query: 332 AVPEIMDRIYKNVMSKVQEMNYIQKTLF----KIGYDYKLEQIKKGYDAP----LCNLLL 383
VP+I ++I++ V + ++K F IG+ +++ Y+ P + L+
Sbjct: 319 GVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLV 378
Query: 384 FKKVKALLG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDY 442
F KVK LG + +SG APL+ +T F + PIG+ YGL+ES G T++ +Y
Sbjct: 379 FSKVKTSLGLDHCHSFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNY 437
Query: 443 TTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSV 502
G L C+ L + G GEI + G++I MGY ++E +T E ++
Sbjct: 438 RLLSCGKILTGCKNMLFQQNKDGI---------GEICLWGRHIFMGYLESETETTE--AI 486
Query: 503 DENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAAL-KNCPLIDNIC 561
D+ G W +GD+G+ G L + K+++ GE V VE + K P+I N
Sbjct: 487 DDEG--WLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISN-- 542
Query: 562 AFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAME------------AEIL 609
A D+ +S + LTL + + G +D N A+ EI+
Sbjct: 543 AMLVGDKLKFLSML------LTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTVTEIV 596
Query: 610 KE--------IREAANAMKLERFEIPIKVR---LSPEPWTPETGLVTDAFKLKRKELRNH 658
K+ I++ NA+ E ++ + + ++ G + KLKR +
Sbjct: 597 KQQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQK 656
Query: 659 YLKDIERMY 667
Y K I+ MY
Sbjct: 657 YKKQIDHMY 665
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 135 bits (339), Expect = 2e-31
Identities = 133/555 (23%), Positives = 230/555 (41%), Gaps = 62/555 (11%)
Query: 37 TLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNN 96
T+ ++F A+ K+G +LG FK+ ++ ++Y +
Sbjct: 104 TVHRMFYEALDKYGDLIALG-----------------FKRQ--DKWEHISYSQYYLLARR 144
Query: 97 FGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESE 156
G LGLK +++AI EW +A + +Y T EA + +
Sbjct: 145 AAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCC 204
Query: 157 ASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSN- 215
A+ ++ + K+ + +K ++ NK +++M+ ELG+
Sbjct: 205 ANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMA-----NVYTMEEFMELGNEV 259
Query: 216 -PENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL--IAGMTGQCERI-PGLGPK 271
E L P+ +++YTSG+TG PKGVM+ N+ A Q I P +
Sbjct: 260 PEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQ 319
Query: 272 DTYIGYLPLAHVLELTAEI-SCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLM 330
+ + YLPL+H+ ++ + +G ++ ++ P +K ++PT
Sbjct: 320 EVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEP-------DALKGSLVNTLREVEPTSH 372
Query: 331 AAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQ-------IKKGYDAPLCNLLL 383
VP + ++I + + + +I++ + LEQ K + L + L+
Sbjct: 373 MGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLV 432
Query: 384 FKKVKALLG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDY 442
KV+ LG + G AP+ +T F + + GYGL+E+ G ++ +Y
Sbjct: 433 LAKVRQALGFAKCQKNFYGAAPMMAETQHFF-LGLNIRLYAGYGLSETSGPHFMSSPYNY 491
Query: 443 TTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSV 502
G + C +KL +N GEI + G+ I MGY E+KT E ++
Sbjct: 492 RLYSSGKLVPGCRVKL---------VNQDAEGIGEICLWGRTIFMGYLNMEDKTCE--AI 540
Query: 503 DENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALK-NCPLIDNIC 561
DE G W TGD G DG L I R K+L+ GE V +E A+K P+I N
Sbjct: 541 DEEG--WLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISN-- 596
Query: 562 AFAKSDQSYVISFVV 576
A DQ +S ++
Sbjct: 597 AMLIGDQRKFLSMLL 611
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 62.8 bits (151), Expect = 1e-09
Identities = 111/479 (23%), Positives = 188/479 (39%), Gaps = 84/479 (17%)
Query: 112 IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKL 171
++ C A +++A + V LY + + + +S++S ++ S E LE
Sbjct: 98 VSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLEL-- 155
Query: 172 KTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM 231
+S V + V + A Y E + V E G +
Sbjct: 156 ------LSPVVRKLGVPLLPLTPAIYTGAVEEPAEVPVPEQGWRNKG------------- 196
Query: 232 AIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEIS 291
A+++YTSG+TGRPKGV+ H N+ A +TG + D + LPL HV + +
Sbjct: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWTKDDVILHVLPLHHVHGVVNALL 255
Query: 292 CFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEM 351
C PL + + + S V + L + P I NV V +
Sbjct: 256 C-----------PLWVGATCVMMPEFSPQQ--VWEKFLSSETPRI------NVFMAVPTI 296
Query: 352 NYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLS-PQTH 410
Y +E + + P L +A+ +R+M+SG A L P
Sbjct: 297 -----------YTKLMEYYDRHFTQPHAQDFL----RAVCEEKIRLMVSGSAALPLPVLE 341
Query: 411 RFMNVCFCCPIGQGYGLTE--SCGAGTVTEVTDYTTGRVGAPLICCEIKL----KDWQEG 464
++ N+ + + YG+TE +G +T G VG PL ++++ +
Sbjct: 342 KWKNITGHTLL-ERYGMTEIGMALSGPLTTAV-RLPGSVGTPLPGVQVRIVSENPQREAC 399
Query: 465 GYTINDKPNPR------------GEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCT 512
YTI+ + + R GE+++ G ++ Y+ E+T +++D WF T
Sbjct: 400 SYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLD----GWFKT 455
Query: 513 GDIGEFHPDGCLQIIDRKK-DLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSY 570
GD F DG I R D++K G VS +VE L P I ++ D ++
Sbjct: 456 GDTVVF-KDGQYWIRGRTSVDIIK-TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW 512
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 62.8 bits (151), Expect = 1e-09
Identities = 111/479 (23%), Positives = 188/479 (39%), Gaps = 84/479 (17%)
Query: 112 IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKL 171
++ C A +++A + V LY + + + +S++S ++ S E LE
Sbjct: 98 VSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLEL-- 155
Query: 172 KTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM 231
+S V + V + A Y E + V E G +
Sbjct: 156 ------LSPVVRKLGVPLLPLTPAIYTGAVEEPAEVPVPEQGWRNKG------------- 196
Query: 232 AIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEIS 291
A+++YTSG+TGRPKGV+ H N+ A +TG + D + LPL HV + +
Sbjct: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWTKDDVILHVLPLHHVHGVVNALL 255
Query: 292 CFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEM 351
C PL + + + S V + L + P I NV V +
Sbjct: 256 C-----------PLWVGATCVMMPEFSPQQ--VWEKFLSSETPRI------NVFMAVPTI 296
Query: 352 NYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLS-PQTH 410
Y +E + + P L +A+ +R+M+SG A L P
Sbjct: 297 -----------YTKLMEYYDRHFTQPHAQDFL----RAVCEEKIRLMVSGSAALPLPVLE 341
Query: 411 RFMNVCFCCPIGQGYGLTE--SCGAGTVTEVTDYTTGRVGAPLICCEIKL----KDWQEG 464
++ N+ + + YG+TE +G +T G VG PL ++++ +
Sbjct: 342 KWKNITGHTLL-ERYGMTEIGMALSGPLTTAV-RLPGSVGTPLPGVQVRIVSENPQREAC 399
Query: 465 GYTINDKPNPR------------GEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCT 512
YTI+ + + R GE+++ G ++ Y+ E+T +++D WF T
Sbjct: 400 SYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLD----GWFKT 455
Query: 513 GDIGEFHPDGCLQIIDRKK-DLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSY 570
GD F DG I R D++K G VS +VE L P I ++ D ++
Sbjct: 456 GDTVVF-KDGQYWIRGRTSVDIIK-TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW 512
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 58.9 bits (141), Expect = 1e-08
Identities = 68/335 (20%), Positives = 135/335 (40%), Gaps = 64/335 (19%)
Query: 234 VMYTSGSTGRPKGVMMHHSNLI--AGMTGQCERIPGLGPKDT-YIGYLPLAHVL-ELTAE 289
+ +TSG+TG PKG + H N++ + + G+ ++ P+ I PL H L +
Sbjct: 260 IQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGT 319
Query: 290 ISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQ 349
+ C YG + +SP+ ++ + +G PT+ + +++++
Sbjct: 320 MMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTM-----------FVDILNQPD 368
Query: 350 EMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQT 409
+Y + + GG + G+P P+
Sbjct: 369 FSSY--------------------------------DISTMCGGVI-----AGSPAPPEL 391
Query: 410 HR-FMNVCFCCPIGQGYGLTESCG---AGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGG 465
R +N + YG TE+ A + + VG + E ++ + + G
Sbjct: 392 IRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGT 451
Query: 466 YTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQ 525
K N GE+ I G + +GY+ +KT E +VD++ +W+ TGD+ + G +
Sbjct: 452 LA---KLNTPGELCIRGYCVMLGYWGEPQKTEE--AVDQD--KWYWTGDVATMNEQGFCK 504
Query: 526 IIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNI 560
I+ R KD++ ++ GE + ++E P + +
Sbjct: 505 IVGRSKDMI-IRGGENIYPAELEDFFHTHPKVQEV 538
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 46.6 bits (109), Expect = 7e-05
Identities = 56/222 (25%), Positives = 94/222 (42%), Gaps = 25/222 (11%)
Query: 381 LLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVT 440
+L+ K +K ++R L+GG PL+P+ V + +GYG TE +
Sbjct: 326 MLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQ 385
Query: 441 DYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQN-----ISMGYFKNEEK 495
+ G +G ++ ++++ D E G + P GEI + + Y N +K
Sbjct: 386 EIKPGSMGKGMLPYDVQIID--ENGNVL--PPGKEGEIALRLKPTRPFCFFSKYVDNPQK 441
Query: 496 TAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCP 555
TA D ++ TGD G DG + R D++ + +G + +VE+AL P
Sbjct: 442 TAATIRGD-----FYVTGDRGVMDSDGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHP 495
Query: 556 LIDNICAFAKSDQ---SYVISFVV-------PNQKRLTLLAQ 587
+ + DQ V +FVV N ++LTL Q
Sbjct: 496 AVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQ 537
Score = 32.0 bits (71), Expect = 1.9
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 17/157 (10%)
Query: 105 GLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSV 164
GL+ + +A+ EW + C + + L + +++ L S+A ++ S
Sbjct: 110 GLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASE 169
Query: 165 ELLESKLKTALLDISCVKHIIYVDNKAINK-AEYPEGFEIHSMQ-SVEELGSNPENLGIP 222
E+ + +++ +L+ +K + V ++ N + E F+ S + S E GS
Sbjct: 170 EVAPA-VESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQ------- 221
Query: 223 PSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT 259
+ + +TSG+TG PK S+L G T
Sbjct: 222 -------EPMTIYFTSGTTGFPKMAQHSQSSLGIGFT 251
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 44.7 bits (104), Expect = 3e-04
Identities = 58/239 (24%), Positives = 98/239 (41%), Gaps = 17/239 (7%)
Query: 75 KKLILGNYKWMNYLEVNRRVNNFGSGL-TALGLKPKNTIAIFCETRAEWMIAAQTCFKYN 133
K +L + + Y +V+RR N L LGL+ + +A+ ++ K
Sbjct: 69 KPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLG 128
Query: 134 FPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAIN 193
+ L + ++++H A L+ S EL ++ ++ L + IY ++ N
Sbjct: 129 CAMACLNYNIRAKSLLHCFQCCGAKVLLVSPEL-QAAVEEILPSLKKDDVSIYYVSRTSN 187
Query: 194 KAEYPEGFEIHSMQSVEELGSNPENLGIPPS---RPTPSDMAIVMYTSGSTGRPKGVMMH 250
+G + + V+E+ + P IP S T S A+ +YTSG+TG PK M+
Sbjct: 188 T----DGIDSF-LDKVDEVSTEP----IPESWRSEVTFSTPALYIYTSGTTGLPKAAMIT 238
Query: 251 HSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYGCRIGYSSPLTLS 308
H + G TG + GL D LP H L I C G + + + S
Sbjct: 239 HQRIWYG-TG-LTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSAS 295
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 40.8 bits (94), Expect = 0.004
Identities = 48/204 (23%), Positives = 84/204 (41%), Gaps = 16/204 (7%)
Query: 370 IKKGYDAPLC-NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLT 428
IK AP+ +LL + + + +++ ++ G L P+T I + YG T
Sbjct: 305 IKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQT 364
Query: 429 ESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQ----- 483
E+ V++ G +G C ++++ D + G + P G+I I +
Sbjct: 365 ETGLTCMVSKTMKIKPGYMGTAASCYDVQIID--DKGNVL--PPGTEGDIGIRVKPIRPI 420
Query: 484 NISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVS 543
I GY N +KTA + D ++ GD G DG Q + R D++ +G +
Sbjct: 421 GIFSGYVDNPDKTAANIRGD-----FWLLGDRGIKDEDGYFQFMGRADDIIN-SSGYRIG 474
Query: 544 LGKVEAALKNCPLIDNICAFAKSD 567
+VE AL P + + D
Sbjct: 475 PSEVENALMEHPAVVETAVISSPD 498
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 40.4 bits (93), Expect = 0.005
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 12/113 (10%)
Query: 194 KAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM---------AIVMYTSGSTGRP 244
+AE F + +G+ L PS P P+D+ A+ +YTSG+TG P
Sbjct: 243 QAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLP 302
Query: 245 KGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYG 296
K ++ H ++ + + G D LPL HV+ L I C G
Sbjct: 303 KPAILTHERVL--QMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLG 353
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 40.4 bits (93), Expect = 0.005
Identities = 37/173 (21%), Positives = 73/173 (42%), Gaps = 17/173 (9%)
Query: 85 MNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLG 144
+ Y E+ + L G+ + +AI+ + A C + ++A
Sbjct: 141 ITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFS 200
Query: 145 KEAVVHGLNESEASYLIT--------SVELLESKLKTALLDISCVKHIIYVDNKAINKAE 196
E++ +N+++ +IT V L+ + A+ V+H++ V ++ NK
Sbjct: 201 AESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVL-VAHRTDNKVH 259
Query: 197 YPE-GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVM 248
+ + + E+ PE++G DM ++YTSGSTG PKG++
Sbjct: 260 MGDLDVPLEQEMAKEDPVCAPESMG-------SEDMLFMLYTSGSTGMPKGIV 305
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 38.5 bits (88), Expect = 0.020
Identities = 41/207 (19%), Positives = 78/207 (37%), Gaps = 48/207 (23%)
Query: 80 GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
G + Y ++ +V F + L G++ + +AI+ E ++A C + +
Sbjct: 131 GETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIV 190
Query: 140 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE 199
+A E++ + +S S LIT+ + L +++ ++A+ K + +
Sbjct: 191 FAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELA---------DEALQKCQ-EK 240
Query: 200 GFEIHSMQSVEELGSNPENLGIPPSRPTP------------------------------- 228
GF + V+ LG +G S+ P
Sbjct: 241 GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISWNQGIDLWWHELMQEAGDEC 300
Query: 229 -------SDMAIVMYTSGSTGRPKGVM 248
D ++YTSGSTG+PKGV+
Sbjct: 301 EPEWCDAEDPLFILYTSGSTGKPKGVV 327
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 38.5 bits (88), Expect = 0.020
Identities = 52/198 (26%), Positives = 81/198 (40%), Gaps = 20/198 (10%)
Query: 89 EVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAV 148
E + V NF L A GL + AIF E R E++ K + L ++A+
Sbjct: 109 EYSSSVANF---LQARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDAL 165
Query: 149 VHGLNESEASYLITSVELLESKLKT-ALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQ 207
+H L S A L+ E+ + + A LD S + G S +
Sbjct: 166 LHCLTTSRARALVFGSEMASAICEVHASLDPSL---------SLFCSGSWEPGAVPPSTE 216
Query: 208 SVEELGSN-PENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL--IAGMTGQCER 264
++ L + P++L P + +D +YTSG+TG PK ++ HS +A + R
Sbjct: 217 HLDPLLKDAPKHLPSCPDKGF-TDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFR 275
Query: 265 IPGLGPKDTYIGYLPLAH 282
+ P D LPL H
Sbjct: 276 ---MRPNDIVYDCLPLYH 290
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 38.5 bits (88), Expect = 0.020
Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 18/205 (8%)
Query: 100 GLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASY 159
G A L P T+A+ E++ K + L + ++H L A
Sbjct: 205 GGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARA 264
Query: 160 LITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF-EIHSMQSVEELGSNPEN 218
L+ + E LES L+ L + + ++ A +P G ++ + S E G P
Sbjct: 265 LVLAPEFLES-LEPDLPALRAMGLHLW----AAGPGTHPAGISDLLAEVSAEVDGPVPGY 319
Query: 219 LGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE---RIPGLGPKDTYI 275
L P S +D + ++TSG+TG PK + H ++ QC+ ++ G+ +D
Sbjct: 320 LSSPQSI---TDTCLYIFTSGTTGLPKAARISHLKIL-----QCQGFYQLCGVHQEDVIY 371
Query: 276 GYLPLAHVL-ELTAEISCFTYGCRI 299
LPL H+ L + C G +
Sbjct: 372 LALPLYHMSGSLLGIVGCMGIGATV 396
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 37.7 bits (86), Expect = 0.035
Identities = 51/200 (25%), Positives = 78/200 (39%), Gaps = 32/200 (16%)
Query: 394 NVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTES---CGAGTVTEVTDYTTGRVGAP 450
+++ +S G P++P I +GYG TE+ CG ++ G +G P
Sbjct: 345 SLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKP---GSMGKP 401
Query: 451 LICCEIKLKD--------WQEGGYTINDKPN-PRGEIVIGGQNISMGYFKNEEKTAEDYS 501
++K+ D QEG I PN P G + Y N KTA
Sbjct: 402 SPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFG--------LFTHYVDNPSKTASTLR 453
Query: 502 VDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNIC 561
+ ++ TGD G DG + R D++ L +G + +VE AL P +
Sbjct: 454 GN-----FYITGDRGYMDKDGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAESA 507
Query: 562 AFAKSDQ---SYVISFVVPN 578
+ D V +FVV N
Sbjct: 508 VVSSPDPIRGEVVKAFVVLN 527
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 36.2 bits (82), Expect = 0.10
Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 11/151 (7%)
Query: 104 LGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITS 163
LG P + +AIF E R E++ K L L +E + L S A LI
Sbjct: 123 LGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFG 182
Query: 164 VELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF--EIHSMQSVEELGSNPENLGI 221
E++ A+ ++S H+ K + PEG + H + + + S I
Sbjct: 183 GEMV-----AAVAEVS--GHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQI 235
Query: 222 PPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 252
P D +YTSG+TG PK ++ HS
Sbjct: 236 PSKGM--DDRLFYIYTSGTTGLPKAAIVVHS 264
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 33.9 bits (76), Expect = 0.50
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 20/126 (15%)
Query: 125 AAQTCFKYNFPL--VTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVK 182
A Q C + FP+ + LG+ + G + S++ + S ++ KLK
Sbjct: 233 ALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEK-------- 284
Query: 183 HIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTG 242
+ + + +G ++ + ++E G E P D ++YTSGSTG
Sbjct: 285 -----SKRVQPQISWNQGIDLWWHELMQEAGDECE-----PEWCDAEDPLFILYTSGSTG 334
Query: 243 RPKGVM 248
+PKGV+
Sbjct: 335 KPKGVV 340
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 33.5 bits (75), Expect = 0.65
Identities = 37/169 (21%), Positives = 77/169 (45%), Gaps = 19/169 (11%)
Query: 89 EVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAV 148
++ RRV N + GL+ + +A+ EW + A C + + L + +
Sbjct: 93 DLTRRVANVFT--QTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDI 150
Query: 149 VHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF-EIHSMQ 207
++ L S+A ++T ++ L S++ + +K + V + + EG+ + S+
Sbjct: 151 LYRLQLSKAKGIVT-IDALASEVDSIASQCPSLKTKLLVSDHS------REGWLDFRSLV 203
Query: 208 SVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIA 256
++PE+ + + D ++ +TSG+TG PK M HS+ +A
Sbjct: 204 K----SASPEHTCV---KSKTLDPMVIFFTSGTTGFPK--MAKHSHGLA 243
>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
Length = 1960
Score = 32.7 bits (73), Expect = 1.1
Identities = 20/88 (22%), Positives = 33/88 (37%)
Query: 262 CERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGD 321
C R+ GL + +H E A + C+ GC Y P + ++
Sbjct: 1869 CGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVR 1928
Query: 322 CTVLKPTLMAAVPEIMDRIYKNVMSKVQ 349
C KP L +P + ++ K +S Q
Sbjct: 1929 CPKHKPPLPCPLPPLQNKTAKGSLSTEQ 1956
>gi|62955829 hypothetical protein LOC90871 [Homo sapiens]
Length = 112
Score = 32.0 bits (71), Expect = 1.9
Identities = 13/31 (41%), Positives = 17/31 (54%)
Query: 402 GAPLSPQTHRFMNVCFCCPIGQGYGLTESCG 432
GAP SP HR + C+ C + G GL + G
Sbjct: 33 GAPTSPAEHRLLKTCWSCRVLSGLGLMGAGG 63
>gi|227499621 solute carrier family 27 (fatty acid transporter),
member 2 isoform 2 [Homo sapiens]
Length = 567
Score = 31.6 bits (70), Expect = 2.5
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 14/172 (8%)
Query: 75 KKLILGNYKWMNYLEVNRRVNNFGSGL-TALGLKPKNTIAIFCETRAEWMIAAQTCFKYN 133
K +L + + Y +V+RR N L LGL+ + +A+ ++ K
Sbjct: 69 KPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLG 128
Query: 134 FPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAIN 193
+ L + ++++H A L+ S EL ++ ++ L + IY ++ N
Sbjct: 129 CAMACLNYNIRAKSLLHCFQCCGAKVLLVSPEL-QAAVEEILPSLKKDDVSIYYVSRTSN 187
Query: 194 KAEYPEGFEIHSMQSVEELGSNPENLGIPPS---RPTPSDMAIVMYTSGSTG 242
+G + + V+E+ + P IP S T S A+ +YTSG+TG
Sbjct: 188 T----DGIDSF-LDKVDEVSTEP----IPESWRSEVTFSTPALYIYTSGTTG 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,128,856
Number of Sequences: 37866
Number of extensions: 1221421
Number of successful extensions: 2739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2649
Number of HSP's gapped (non-prelim): 44
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.