Guide to the Human Genome
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Search of human proteins with 4758150

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758150 DNA fragmentation factor, 40 kD, beta polypeptide
[Homo sapiens]
         (338 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758150 DNA fragmentation factor, 40 kD, beta polypeptide [Ho...   693   0.0  
gi|23943904 cell death-inducing DFFA-like effector c [Homo sapiens]    37   0.025
gi|38158011 cell death-inducing DFFA-like effector a isoform 2 [...    37   0.033
gi|4557465 cell death-inducing DFFA-like effector a isoform 1 [H...    37   0.033
gi|47132600 DNA fragmentation factor, 45kDa, alpha polypeptide i...    33   0.47 
gi|4758148 DNA fragmentation factor, 45kDa, alpha polypeptide is...    33   0.47 
gi|93102358 cell death-inducing DFFA-like effector b [Homo sapiens]    32   0.81 
gi|239754825 PREDICTED: hypothetical protein [Homo sapiens]            30   4.0  
gi|239755736 PREDICTED: hypothetical protein [Homo sapiens]            29   6.8  
gi|239750248 PREDICTED: hypothetical protein XP_002347331 [Homo ...    29   6.8  
gi|239744550 PREDICTED: hypothetical protein XP_002343193 [Homo ...    29   6.8  
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...    28   8.9  
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor...    28   8.9  
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...    28   8.9  
gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo...    28   8.9  
gi|67190748 complement component 4A preproprotein [Homo sapiens]       28   8.9  
gi|178557739 complement component 4B preproprotein [Homo sapiens]      28   8.9  
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...    28   8.9  
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    28   8.9  
gi|239758130 PREDICTED: similar to complement component 4B (Chil...    28   8.9  
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s...    28   8.9  
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s...    28   8.9  

>gi|4758150 DNA fragmentation factor, 40 kD, beta polypeptide [Homo
           sapiens]
          Length = 338

 Score =  693 bits (1789), Expect = 0.0
 Identities = 338/338 (100%), Positives = 338/338 (100%)

Query: 1   MLQKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYF 60
           MLQKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYF
Sbjct: 1   MLQKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYF 60

Query: 61  PSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQAPQRQRLLA 120
           PSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQAPQRQRLLA
Sbjct: 61  PSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQAPQRQRLLA 120

Query: 121 DLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTVGA 180
           DLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTVGA
Sbjct: 121 DLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTVGA 180

Query: 181 EAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHS 240
           EAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHS
Sbjct: 181 EAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHS 240

Query: 241 INPYSNRESRILFSTWNLDHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLK 300
           INPYSNRESRILFSTWNLDHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLK
Sbjct: 241 INPYSNRESRILFSTWNLDHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLK 300

Query: 301 LVHIVCHKKTTHKLNCDPSRIYKPQTRLKRKQPVRKRQ 338
           LVHIVCHKKTTHKLNCDPSRIYKPQTRLKRKQPVRKRQ
Sbjct: 301 LVHIVCHKKTTHKLNCDPSRIYKPQTRLKRKQPVRKRQ 338


>gi|23943904 cell death-inducing DFFA-like effector c [Homo sapiens]
          Length = 238

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 3/84 (3%)

Query: 14  RSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTEL-TEDYFPSVPDNAELVLL 72
           RS RK G+   S +++L K      L ++   L L EDGT + TE+YF ++  +   ++L
Sbjct: 52  RSVRK-GIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVL 110

Query: 73  TLGQAWQ-GYVSDIRRFLSAFHEP 95
             GQ WQ       R  LS  H+P
Sbjct: 111 QKGQKWQPPSEQGTRHPLSLSHKP 134


>gi|38158011 cell death-inducing DFFA-like effector a isoform 2
           [Homo sapiens]
          Length = 253

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 2/66 (3%)

Query: 14  RSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTEL-TEDYFPSVPDNAELVLL 72
           RS R+ GV   S QE++ K      +      L L EDGT + TE++F ++ DN   ++L
Sbjct: 78  RSSRR-GVMASSLQELISKTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMIL 136

Query: 73  TLGQAW 78
             GQ W
Sbjct: 137 EKGQKW 142


>gi|4557465 cell death-inducing DFFA-like effector a isoform 1 [Homo
           sapiens]
          Length = 219

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 2/66 (3%)

Query: 14  RSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTEL-TEDYFPSVPDNAELVLL 72
           RS R+ GV   S QE++ K      +      L L EDGT + TE++F ++ DN   ++L
Sbjct: 44  RSSRR-GVMASSLQELISKTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMIL 102

Query: 73  TLGQAW 78
             GQ W
Sbjct: 103 EKGQKW 108


>gi|47132600 DNA fragmentation factor, 45kDa, alpha polypeptide
           isoform 2 [Homo sapiens]
          Length = 268

 Score = 32.7 bits (73), Expect = 0.47
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 6   KSVKLRALRSPRKFGVAGRSCQEVLRKGC--LRFQLPERGSRLCLYEDGTELTED-YFPS 62
           K   LR   S  + GVA    +++  K C  L          L L EDGT + +D YF  
Sbjct: 19  KPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLC 78

Query: 63  VPDNAELVLLTLGQAWQGYVSD 84
           +P N + V L   + W    SD
Sbjct: 79  LPSNTKFVALASNEKWAYNNSD 100


>gi|4758148 DNA fragmentation factor, 45kDa, alpha polypeptide
           isoform 1 [Homo sapiens]
          Length = 331

 Score = 32.7 bits (73), Expect = 0.47
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 6   KSVKLRALRSPRKFGVAGRSCQEVLRKGC--LRFQLPERGSRLCLYEDGTELTED-YFPS 62
           K   LR   S  + GVA    +++  K C  L          L L EDGT + +D YF  
Sbjct: 19  KPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLC 78

Query: 63  VPDNAELVLLTLGQAWQGYVSD 84
           +P N + V L   + W    SD
Sbjct: 79  LPSNTKFVALASNEKWAYNNSD 100


>gi|93102358 cell death-inducing DFFA-like effector b [Homo sapiens]
          Length = 219

 Score = 32.0 bits (71), Expect = 0.81
 Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 3/66 (4%)

Query: 14  RSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTEL-TEDYFPSVPDNAELVLL 72
           R+ RK G+   + QE+L K  L   L      L L EDGT + +ED+F  + D+  L++L
Sbjct: 45  RTIRK-GLTAATRQELLAKA-LETLLLNGVLTLVLEEDGTAVDSEDFFQLLEDDTCLMVL 102

Query: 73  TLGQAW 78
             GQ+W
Sbjct: 103 QSGQSW 108


>gi|239754825 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 135

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 3/36 (8%)

Query: 51 DGTELTEDYFPSVPDNAELVLLTLGQAWQGYVSDIR 86
          DG  L   +  S+P   +L+L + G+AW+G VSDIR
Sbjct: 20 DGISLPRSFNESLP---QLLLGSGGEAWKGPVSDIR 52


>gi|239755736 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 136

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 51 DGTELTEDYFPSVPDNAELVLLTLGQAWQGYVSDIRR 87
          DG  L   +  S+P   +L+L + G+ W+G VSDIR+
Sbjct: 20 DGISLPRSFSESLP---QLLLGSGGEPWKGPVSDIRK 53


>gi|239750248 PREDICTED: hypothetical protein XP_002347331 [Homo
          sapiens]
          Length = 136

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 51 DGTELTEDYFPSVPDNAELVLLTLGQAWQGYVSDIRR 87
          DG  L   +  S+P   +L+L + G+ W+G VSDIR+
Sbjct: 20 DGISLPRSFSESLP---QLLLGSGGEPWKGPVSDIRK 53


>gi|239744550 PREDICTED: hypothetical protein XP_002343193 [Homo
          sapiens]
          Length = 136

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 51 DGTELTEDYFPSVPDNAELVLLTLGQAWQGYVSDIRR 87
          DG  L   +  S+P   +L+L + G+ W+G VSDIR+
Sbjct: 20 DGISLPRSFSESLP---QLLLGSGGEPWKGPVSDIRK 53


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 96  QVGLIQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY 155
           +  L QA+ Q   D  APQR  + +   HN+S +  A  R   P    G+ SR    +G 
Sbjct: 490 RASLGQASIQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTNFP---RGVSSRSTFHAGQ 546

Query: 156 LR 157
           LR
Sbjct: 547 LR 548


>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
           [Homo sapiens]
          Length = 719

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 96  QVGLIQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY 155
           +  L QA+ Q   D  APQR  + +   HN+S +  A  R   P    G+ SR    +G 
Sbjct: 491 RASLGQASIQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTNFP---RGVSSRSTFHAGQ 547

Query: 156 LR 157
           LR
Sbjct: 548 LR 549


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 96  QVGLIQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY 155
           +  L QA+ Q   D  APQR  + +   HN+S +  A  R   P    G+ SR    +G 
Sbjct: 490 RASLGQASIQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTNFP---RGVSSRSTFHAGQ 546

Query: 156 LR 157
           LR
Sbjct: 547 LR 548


>gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo
           sapiens]
          Length = 1297

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 11/30 (36%), Positives = 18/30 (60%)

Query: 268 IIPTLVEAIKEQDGREVDWEYFYGLLFTSE 297
           ++  + E I+ Q G+E + EYF  L+ T E
Sbjct: 127 VLAAVTEVIRSQGGKETETEYFAALMTTME 156


>gi|67190748 complement component 4A preproprotein [Homo sapiens]
          Length = 1744

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 32/114 (28%), Positives = 43/114 (37%), Gaps = 32/114 (28%)

Query: 59   YFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQ------- 111
            YF SVP + E V         G+         A  E  VGL+Q A   L D         
Sbjct: 1525 YFDSVPTSRECV---------GF--------EAVQEVPVGLVQPASATLYDYYNPERRCS 1567

Query: 112  ----APQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY-LRYSC 160
                AP + RLLA L    S  +      + P     LE   Q + GY ++++C
Sbjct: 1568 VFYGAPSKSRLLATL---CSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC 1618


>gi|178557739 complement component 4B preproprotein [Homo sapiens]
          Length = 1744

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 32/114 (28%), Positives = 43/114 (37%), Gaps = 32/114 (28%)

Query: 59   YFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQ------- 111
            YF SVP + E V         G+         A  E  VGL+Q A   L D         
Sbjct: 1525 YFDSVPTSRECV---------GF--------EAVQEVPVGLVQPASATLYDYYNPERRCS 1567

Query: 112  ----APQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY-LRYSC 160
                AP + RLLA L    S  +      + P     LE   Q + GY ++++C
Sbjct: 1568 VFYGAPSKSRLLATL---CSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC 1618


>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 1632

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 3   QKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYFPS 62
           Q+P+  K +A +   KFG +GRS Q    + C    + E         D  E  +D  P 
Sbjct: 676 QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKE--------ADDDEEVDDNIPE 727

Query: 63  VP 64
           +P
Sbjct: 728 MP 729


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 1616

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 3   QKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYFPS 62
           Q+P+  K +A +   KFG +GRS Q    + C    + E         D  E  +D  P 
Sbjct: 660 QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKE--------ADDDEEVDDNIPE 711

Query: 63  VP 64
           +P
Sbjct: 712 MP 713


>gi|239758130 PREDICTED: similar to complement component 4B (Childo
           blood group), partial [Homo sapiens]
          Length = 666

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 32/114 (28%), Positives = 43/114 (37%), Gaps = 32/114 (28%)

Query: 59  YFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQ------- 111
           YF SVP + E V         G+         A  E  VGL+Q A   L D         
Sbjct: 447 YFDSVPTSRECV---------GF--------EAVQEVPVGLVQPASATLYDYYNPERRCS 489

Query: 112 ----APQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY-LRYSC 160
               AP + RLLA L    S  +      + P     LE   Q + GY ++++C
Sbjct: 490 VFYGAPSKSRLLATL---CSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC 540


>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
            sapiens]
          Length = 1698

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 32/114 (28%), Positives = 43/114 (37%), Gaps = 32/114 (28%)

Query: 59   YFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQ------- 111
            YF SVP + E V         G+         A  E  VGL+Q A   L D         
Sbjct: 1479 YFDSVPTSRECV---------GF--------EAVQEVPVGLVQPASATLYDYYNPERRCS 1521

Query: 112  ----APQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY-LRYSC 160
                AP + RLLA L    S  +      + P     LE   Q + GY ++++C
Sbjct: 1522 VFYGAPSKSRLLATL---CSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC 1572


>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
            sapiens]
          Length = 1744

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 32/114 (28%), Positives = 43/114 (37%), Gaps = 32/114 (28%)

Query: 59   YFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQ------- 111
            YF SVP + E V         G+         A  E  VGL+Q A   L D         
Sbjct: 1525 YFDSVPTSRECV---------GF--------EAVQEVPVGLVQPASATLYDYYNPERRCS 1567

Query: 112  ----APQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGY-LRYSC 160
                AP + RLLA L    S  +      + P     LE   Q + GY ++++C
Sbjct: 1568 VFYGAPSKSRLLATL---CSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC 1618


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,544,786
Number of Sequences: 37866
Number of extensions: 602596
Number of successful extensions: 1325
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1323
Number of HSP's gapped (non-prelim): 22
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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