BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens] (1085 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens] 2206 0.0 gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s... 119 2e-26 gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa... 57 9e-08 gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07 gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07 gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07 gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07 gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07 gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat... 53 2e-06 gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 52 2e-06 gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 52 2e-06 gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 52 4e-06 gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens] 51 5e-06 gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens] 51 5e-06 gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens] 51 5e-06 gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens] 49 2e-05 gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens] 49 2e-05 gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens] 49 3e-05 gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat... 49 3e-05 gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat... 49 3e-05 gi|4506529 rhodopsin kinase [Homo sapiens] 48 4e-05 gi|217330634 serine/threonine kinase 36 [Homo sapiens] 47 7e-05 gi|23943882 serine/threonine kinase 33 [Homo sapiens] 47 1e-04 gi|32698688 citron [Homo sapiens] 47 1e-04 gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 47 1e-04 gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] 45 3e-04 gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] 45 3e-04 gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens] 45 3e-04 gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a... 44 6e-04 gi|4507831 Unc-51-like kinase 1 [Homo sapiens] 44 8e-04 >gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens] Length = 1085 Score = 2206 bits (5716), Expect = 0.0 Identities = 1085/1085 (100%), Positives = 1085/1085 (100%) Query: 1 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 60 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK Sbjct: 1 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 60 Query: 61 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 120 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA Sbjct: 61 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 120 Query: 121 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 180 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN Sbjct: 121 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 180 Query: 181 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 240 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE Sbjct: 181 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 240 Query: 241 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 300 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL Sbjct: 241 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 300 Query: 301 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 360 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP Sbjct: 301 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 360 Query: 361 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 420 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG Sbjct: 361 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 420 Query: 421 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 480 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL Sbjct: 421 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 480 Query: 481 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 540 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL Sbjct: 481 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 540 Query: 541 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 600 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF Sbjct: 541 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 600 Query: 601 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 660 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK Sbjct: 601 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 660 Query: 661 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 720 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA Sbjct: 661 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 720 Query: 721 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 780 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF Sbjct: 721 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 780 Query: 781 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 840 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER Sbjct: 781 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 840 Query: 841 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 900 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR Sbjct: 841 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 900 Query: 901 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 960 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT Sbjct: 901 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 960 Query: 961 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 1020 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR Sbjct: 961 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 1020 Query: 1021 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1080 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC Sbjct: 1021 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1080 Query: 1081 KRSRK 1085 KRSRK Sbjct: 1081 KRSRK 1085 >gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo sapiens] Length = 1050 Score = 119 bits (298), Expect = 2e-26 Identities = 59/161 (36%), Positives = 93/161 (57%), Gaps = 2/161 (1%) Query: 2 DTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPEN--KEYLITLLEHLMKEFLDK 59 +T + + E ++ Y GNDPL W+RYI W E+N+P+ + + TLLE ++ + Sbjct: 53 NTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGE 112 Query: 60 KKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHAS 119 K+Y++DPRF++ LK ++ + +L+N GIG + YI+WA EA+ + A Sbjct: 113 KRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKAD 172 Query: 120 AVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSE 160 A+ Q GIQ +AEP E LQ Q+R FQ R++ L A + E Sbjct: 173 AIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEE 213 Score = 112 bits (280), Expect = 2e-24 Identities = 123/514 (23%), Positives = 223/514 (43%), Gaps = 74/514 (14%) Query: 567 EEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFHK------LPVESVH 620 +E E +D+ + G R N T+ P+P+ DF AA+ STPFH+ LP + Sbjct: 579 DEFTGIEPLSEDAIITGFR-NVTICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPER 637 Query: 621 ILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYSASLLRLSQ 680 +L +++ V Q T + + + K SPI E S ++A S +S S ++ Sbjct: 638 LLPEEDLDVKTSEDQQTACGTIYSQTLSIK--KLSPIIEDS-REATHSSGFSGSSASVAS 694 Query: 681 PAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQAEWMQMSSLGTVDAPNFIVGN 740 ++ L +L LT+ + E+P + Sbjct: 695 TSSIKCLQIPEKL-----ELTNETS---ENPTQS-------------------------- 720 Query: 741 PWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQ 800 PW + +LL L + +S E + +P ++ + E +LG++ + E + Sbjct: 721 PWCSQYRRQLLKSLPELSASAELCIEDR-PMPKLEIEKEIELGNEDYCIKR---EYLICE 776 Query: 801 VYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQN 860 Y+ + + + V+KV PW+FYI +L ERL H F S + +Q+ Sbjct: 777 DYKLFW--VAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDH----FCSCYQYQD 830 Query: 861 GSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKP 920 G ++ + + TL + + + + + + +L ++E +H EI+HGD+ P Sbjct: 831 GCIVWHQYINCFTLQDLLQ-----HSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSP 885 Query: 921 DNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEML--- 977 IL N + D + + L ++D S+D+++ + +FT SGF+ V++L Sbjct: 886 RCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRV--QLDVFTL----SGFRTVQILEGQ 939 Query: 978 ---SNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLDMWNEFFHV 1034 +N YQ+D FG+A + +LF +++V +G K L ++WN+FF Sbjct: 940 KILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVR 999 Query: 1035 MLNIPDCHHLPSLDLLRQKLKKVFQ---QHYTNK 1065 +LN D + L L ++ VF Q + NK Sbjct: 1000 ILNANDEATVSVLGELAAEMNGVFDTTFQSHLNK 1033 Score = 51.6 bits (122), Expect = 4e-06 Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%) Query: 221 VHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKE 280 V S + + ++ +MYCKEK+ G EFSFEE+RA+ + ++ K ++ KR E Sbjct: 382 VQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAE 441 Query: 281 ANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERS 318 ++++++E+ KKL ++ T E QE + Sbjct: 442 --------MQKQIEEMEKKLKEIQTTQQERTGDQQEET 471 >gi|7657214 hormonally upregulated Neu-associated kinase [Homo sapiens] Length = 714 Score = 57.0 bits (136), Expect = 9e-08 Identities = 53/215 (24%), Positives = 93/215 (43%), Gaps = 27/215 (12%) Query: 793 LGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKF 852 LGEG+FA+V E L+ ++ + + K + Y+ L R + +Q M Sbjct: 68 LGEGSFAKVREG----LHVLTGEKVAIKVIDKKRAKKDTYVTKNL--RREGQIQQMIRHP 121 Query: 853 YSAHLF-----QNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQ 907 L +N LV EL G L++ I K E + + +++ +E Sbjct: 122 NITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARR-----YIRQLISAVEH 176 Query: 908 VHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCE 967 +H ++H D+K +N +L DED+ + LID G S + F+ +C Sbjct: 177 LHRAGVVHRDLKIENLLL--------DEDN---NIKLIDFGLSNCAGILGYSDPFSTQCG 225 Query: 968 TSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGT 1002 + + E+L+ K + +ID + + +Y ML GT Sbjct: 226 SPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGT 260 >gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 5 [Homo sapiens] Length = 529 Score = 54.3 bits (129), Expect = 6e-07 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847 + L+G+G+F QV +A D ++ +K+ K N F Q+ RL M Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019 ++ ++ E+L P++ ID + + + M G E LF Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361 Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057 +D N+ V L IP H L R+ +K+ Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398 >gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 4 [Homo sapiens] Length = 540 Score = 54.3 bits (129), Expect = 6e-07 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847 + L+G+G+F QV +A D ++ +K+ K N F Q+ RL M Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019 ++ ++ E+L P++ ID + + + M G E LF Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361 Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057 +D N+ V L IP H L R+ +K+ Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398 >gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 3 [Homo sapiens] Length = 584 Score = 54.3 bits (129), Expect = 6e-07 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847 + L+G+G+F QV +A D ++ +K+ K N F Q+ RL M Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019 ++ ++ E+L P++ ID + + + M G E LF Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361 Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057 +D N+ V L IP H L R+ +K+ Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398 >gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 2 [Homo sapiens] Length = 754 Score = 54.3 bits (129), Expect = 6e-07 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847 + L+G+G+F QV +A D ++ +K+ K N F Q+ RL M Sbjct: 152 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 204 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M Sbjct: 205 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 260 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 261 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 306 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019 ++ ++ E+L P++ ID + + + M G E LF Sbjct: 307 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 352 Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057 +D N+ V L IP H L R+ +K+ Sbjct: 353 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 389 >gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 1 [Homo sapiens] Length = 763 Score = 54.3 bits (129), Expect = 6e-07 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847 + L+G+G+F QV +A D ++ +K+ K N F Q+ RL M Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019 ++ ++ E+L P++ ID + + + M G E LF Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361 Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057 +D N+ V L IP H L R+ +K+ Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398 >gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B isoform b [Homo sapiens] Length = 589 Score = 52.8 bits (125), Expect = 2e-06 Identities = 74/301 (24%), Positives = 124/301 (41%), Gaps = 50/301 (16%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847 + L+G+G+F QV +A D + ++ +K+ K N F Q+ RL M QH Sbjct: 113 IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV EL SY N +L +NT + + L A ++ Sbjct: 166 DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 222 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019 ++ ++ E+L P++ ID + + + M G E LF Sbjct: 268 QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG--------------EPLF 313 Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYT-NKIRALRNRLIVLLL 1078 +D N V L IP L R+ +++ +T + + LR L++ +L Sbjct: 314 SGSNEVDQMNRIVEV-LGIPPAAMLDQAPKARKYFERLPGGGWTLRRTKELRKDLVLRML 372 Query: 1079 E 1079 E Sbjct: 373 E 373 >gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1 [Homo sapiens] Length = 357 Score = 52.4 bits (124), Expect = 2e-06 Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 26/220 (11%) Query: 785 KLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERL 841 K+ LG GAF++V E G L K K LK ++ + E + ++ Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHEN 80 Query: 842 KPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 +++ ++ HL+ LV +L S G L + I EK + ++ Sbjct: 81 IVALEDIYES--PNHLY-----LVMQLVSGGELFDRIVEKGFYTEKDAS-----TLIRQV 128 Query: 902 LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961 L + +H I+H D+KP+N + + QD+E + + D G S K+ KG + Sbjct: 129 LDAVYYLHRMGIVHRDLKPENLL----YYSQDEESKIM----ISDFGLS---KMEGKGDV 177 Query: 962 FTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 + C T G+ E+L+ KP++ +D + + Y +L G Sbjct: 178 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCG 217 >gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2 [Homo sapiens] Length = 385 Score = 52.4 bits (124), Expect = 2e-06 Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 26/220 (11%) Query: 785 KLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERL 841 K+ LG GAF++V E G L K K LK ++ + E + ++ Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHEN 80 Query: 842 KPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 +++ ++ HL+ LV +L S G L + I EK + ++ Sbjct: 81 IVALEDIYES--PNHLY-----LVMQLVSGGELFDRIVEKGFYTEKDAS-----TLIRQV 128 Query: 902 LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961 L + +H I+H D+KP+N + + QD+E + + D G S K+ KG + Sbjct: 129 LDAVYYLHRMGIVHRDLKPENLL----YYSQDEESKIM----ISDFGLS---KMEGKGDV 177 Query: 962 FTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 + C T G+ E+L+ KP++ +D + + Y +L G Sbjct: 178 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCG 217 >gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo sapiens] Length = 370 Score = 51.6 bits (122), Expect = 4e-06 Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 12/137 (8%) Query: 866 GELYSYGTLLNAINLYKNTPEK-VMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNFI 924 G LY L++ L+ EK + ++L ++ +HD I+H D+KP+N + Sbjct: 89 GHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLL 148 Query: 925 LGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWNY 984 + L++D + + + D G S K+ G++ + C T G+ E+L+ KP++ Sbjct: 149 YYS--LDEDSK------IMISDFGLS---KMEDPGSVLSTACGTPGYVAPEVLAQKPYSK 197 Query: 985 QIDYFGVAATVYCMLFG 1001 +D + + Y +L G Sbjct: 198 AVDCWSIGVIAYILLCG 214 >gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens] Length = 470 Score = 51.2 bits (121), Expect = 5e-06 Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%) Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808 K +SG S +S+YP T L ++ + LG G+F VY Sbjct: 9 KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45 Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863 ++D K K+ LKV K + E + L +L + H +KF+++ + Q+ Sbjct: 46 VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105 Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923 ++ E L + I YK K+ P+ +I + +++L ++ +H+ I+H D+K N Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164 Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983 L N L+ D G++ + +G S D+ T T + E L ++ ++ Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210 Query: 984 YQIDYFGVAATVYCM 998 + D + +A +Y M Sbjct: 211 TKSDIWSLACILYEM 225 >gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens] Length = 599 Score = 51.2 bits (121), Expect = 5e-06 Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%) Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808 K +SG S +S+YP T L ++ + LG G+F VY Sbjct: 9 KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45 Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863 ++D K K+ LKV K + E + L +L + H +KF+++ + Q+ Sbjct: 46 VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105 Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923 ++ E L + I YK K+ P+ +I + +++L ++ +H+ I+H D+K N Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164 Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983 L N L+ D G++ + +G S D+ T T + E L ++ ++ Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210 Query: 984 YQIDYFGVAATVYCM 998 + D + +A +Y M Sbjct: 211 TKSDIWSLACILYEM 225 >gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens] Length = 645 Score = 51.2 bits (121), Expect = 5e-06 Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%) Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808 K +SG S +S+YP T L ++ + LG G+F VY Sbjct: 9 KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45 Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863 ++D K K+ LKV K + E + L +L + H +KF+++ + Q+ Sbjct: 46 VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105 Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923 ++ E L + I YK K+ P+ +I + +++L ++ +H+ I+H D+K N Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164 Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983 L N L+ D G++ + +G S D+ T T + E L ++ ++ Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210 Query: 984 YQIDYFGVAATVYCM 998 + D + +A +Y M Sbjct: 211 TKSDIWSLACILYEM 225 >gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens] Length = 347 Score = 49.3 bits (116), Expect = 2e-05 Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 23/178 (12%) Query: 761 YPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEAT---QGDLNDAKNKQK 817 +PNT ++C L +FQ+ K+ G G F++VY+AT K Q Sbjct: 66 HPNTLSFRCSL------ADFQIEKKI-------GRGQFSEVYKATCLLDRKTVALKKVQI 112 Query: 818 FVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNA 877 F + K IG LK +K+ + + N +V EL G L Sbjct: 113 FEMMDAKARQDCVKEIGL-----LKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQM 167 Query: 878 INLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDN-FILGNGFLEQDD 934 I +K ++++P+ V + +++ +E +H ++H DIKP N FI G ++ D Sbjct: 168 IKYFKKQ-KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGD 224 >gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens] Length = 313 Score = 49.3 bits (116), Expect = 2e-05 Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 23/178 (12%) Query: 761 YPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEAT---QGDLNDAKNKQK 817 +PNT ++C L +FQ+ K+ G G F++VY+AT K Q Sbjct: 32 HPNTLSFRCSL------ADFQIEKKI-------GRGQFSEVYKATCLLDRKTVALKKVQI 78 Query: 818 FVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNA 877 F + K IG LK +K+ + + N +V EL G L Sbjct: 79 FEMMDAKARQDCVKEIGL-----LKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQM 133 Query: 878 INLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDN-FILGNGFLEQDD 934 I +K ++++P+ V + +++ +E +H ++H DIKP N FI G ++ D Sbjct: 134 IKYFKKQ-KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGD 190 >gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens] Length = 553 Score = 48.9 bits (115), Expect = 3e-05 Identities = 54/221 (24%), Positives = 97/221 (43%), Gaps = 40/221 (18%) Query: 792 LLGEGAFAQVYEA---TQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLK-PSMQH 847 +LG+G F +V G + K K LK K + +++E++ P + Sbjct: 196 VLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLK--KKGGEKMALLEKEILEKVSSPFIVS 253 Query: 848 MFMKFYS-AHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 + F S HL NG L +Y+ GT + + VI ++ ++ Sbjct: 254 LAYAFESKTHLCLVMSLMNGGDLKFHIYNVGT-------------RGLDMSRVIFYSAQI 300 Query: 902 LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961 + +H+ I++ D+KP+N +L DDL L DLG +++MK G Sbjct: 301 ACGMLHLHELGIVYRDMKPENVLL----------DDL-GNCRLSDLGLAVEMK---GGKP 346 Query: 962 FTAKCETSGFQCVEMLSNK-PWNYQIDYFGVAATVYCMLFG 1001 T + T+G+ E+L K ++Y +D+F + ++Y M+ G Sbjct: 347 ITQRAGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAG 387 >gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B isoform a [Homo sapiens] Length = 629 Score = 48.5 bits (114), Expect = 3e-05 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847 + L+G+G+F QV +A D + ++ +K+ K N F Q+ RL M QH Sbjct: 113 IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV EL SY N +L +NT + + L A ++ Sbjct: 166 DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 222 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 ++ ++ E+L P++ ID + + + M G Sbjct: 268 QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG 309 >gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B isoform c [Homo sapiens] Length = 601 Score = 48.5 bits (114), Expect = 3e-05 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%) Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847 + L+G+G+F QV +A D + ++ +K+ K N F Q+ RL M QH Sbjct: 113 IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165 Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901 MK+Y HL F+N LV EL SY N +L +NT + + L A ++ Sbjct: 166 DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221 Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959 + + IIH D+KP+N +L N + + ++D G S + G Sbjct: 222 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267 Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 ++ ++ E+L P++ ID + + + M G Sbjct: 268 QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG 309 >gi|4506529 rhodopsin kinase [Homo sapiens] Length = 563 Score = 48.1 bits (113), Expect = 4e-05 Identities = 47/216 (21%), Positives = 93/216 (43%), Gaps = 32/216 (14%) Query: 792 LLGEGAFAQVYEATQ---GDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHM 848 +LG+G F +V G L K K LK +K Y G + +++ + Sbjct: 195 VLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKG------YQGAMVEKKILMKVHSR 248 Query: 849 FMKFYSAHLFQNGSVLVGELYSYGTLLNA----INLYK-NTPEKVMPQGLVISFAMRMLY 903 F+ A+ F+ + +L T++N ++Y N P+ + + +++ Sbjct: 249 FIVSL-AYAFETKA----DLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIIC 303 Query: 904 MIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFT 963 +E +H I++ D+KP+N +L N + + DLG ++++ T Sbjct: 304 GLEHLHQRRIVYRDLKPENVLLDN-----------DGNVRISDLGLAVELLDGQSKT--K 350 Query: 964 AKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCML 999 T GF E+L + +++ +DYF + T+Y M+ Sbjct: 351 GYAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMI 386 >gi|217330634 serine/threonine kinase 36 [Homo sapiens] Length = 1315 Score = 47.4 bits (111), Expect = 7e-05 Identities = 47/217 (21%), Positives = 94/217 (43%), Gaps = 26/217 (11%) Query: 788 YVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWE-FYIGTQLMERLK-PSM 845 +V ++GEG+F +VY+ + + KF+ K+ + ++M L+ P++ Sbjct: 5 HVLEMIGEGSFGRVYKGRR-KYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNI 63 Query: 846 QHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMI 905 HM F + + V+V Y+ G L + + +P+ V + A +++ + Sbjct: 64 VHMLDSFET-----DKEVVVVTDYAEGELFQILE-----DDGKLPEDQVQAIAAQLVSAL 113 Query: 906 EQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAK 965 +H I+H D+KP N +L G G+ L D G + M + T+ Sbjct: 114 YYLHSHRILHRDMKPQNILLAKG-----------GGIKLCDFGFARAMS--TNTMVLTSI 160 Query: 966 CETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGT 1002 T + E++ +P+++ D + V +Y + GT Sbjct: 161 KGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGT 197 >gi|23943882 serine/threonine kinase 33 [Homo sapiens] Length = 514 Score = 47.0 bits (110), Expect = 1e-04 Identities = 48/215 (22%), Positives = 100/215 (46%), Gaps = 21/215 (9%) Query: 792 LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER---LKPSMQHM 848 +LG+G+F V EAT D + + K+ +K + +L+ER + S++H Sbjct: 121 ILGKGSFGIVIEAT-----DKETETKWAIKKVNKEKAGSSAV--KLLEREVNILKSVKHE 173 Query: 849 FMKFYSAHLFQNGS--VLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIE 906 + + +F+ LV EL G L ++ + E + ++ S A + Y+ Sbjct: 174 HI-IHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENET-RWIIQSLASAIAYL-- 229 Query: 907 QVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKC 966 H+ +I+H D+K +N ++ + + DD ++++ + + D G ++ K + A C Sbjct: 230 --HNNDIVHRDLKLENIMVKSSLI--DDNNEINLNIKVTDFGLAV-KKQSRSEAMLQATC 284 Query: 967 ETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 T + E++S ++ Q D + + +Y +L G Sbjct: 285 GTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRG 319 >gi|32698688 citron [Homo sapiens] Length = 2027 Score = 46.6 bits (109), Expect = 1e-04 Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 38/236 (16%) Query: 779 EFQLGSKLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFY--I 833 E Q +K V L+G G FA+V E GD+ K +K L Q+ + +E I Sbjct: 89 ELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNI 148 Query: 834 GTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGL 893 ++ P +Q+ F +N LV E G LL+ +N Y E + + L Sbjct: 149 LSRSTSPWIPQLQYAFQD-------KNHLYLVMEYQPGGDLLSLLNRY----EDQLDENL 197 Query: 894 VISFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDM 953 + + ++ + VH +H DIKP+N ++ D + + L+D G + M Sbjct: 198 IQFYLAELILAVHSVHLMGYVHRDIKPENILV-----------DRTGHIKLVDFGSAAKM 246 Query: 954 KLFPKGTIFTAKCE--TSGFQCVEMLS------NKPWNYQIDYFGVAATVYCMLFG 1001 + AK T + E+L+ + D++ V Y M++G Sbjct: 247 N---SNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYG 299 Score = 30.8 bits (68), Expect = 7.3 Identities = 43/215 (20%), Positives = 93/215 (43%), Gaps = 37/215 (17%) Query: 108 HLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQV 167 H EAQ QH L++ Q+ E + L Q + + L + + Sbjct: 700 HREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIK------------------KDLADKET 741 Query: 168 LNQMITSKSNPGNNMACISKNQGSELSGVISSACDKESNMERRVITISKS-EYSVHSSLA 226 L M+ + I SE +I++ K ++E+R++ +S++ + + +SSL Sbjct: 742 LENMMQRHEEEAHEKGKIL----SEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLF 797 Query: 227 SKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEE 286 ++ + M +E++I ELR QK+ + + ++R ++ E + ++ Sbjct: 798 TQRN-----MKAQEEMI--------SELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQD 844 Query: 287 QLLKQKMDELHKKLHQV-VETSHEDLPASQERSEV 320 K ++ EL +L +V +E + L ++ +E+ Sbjct: 845 HSDKNRLLELETRLREVSLEHEEQKLELKRQLTEL 879 >gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo sapiens] Length = 476 Score = 46.6 bits (109), Expect = 1e-04 Identities = 52/210 (24%), Positives = 92/210 (43%), Gaps = 22/210 (10%) Query: 792 LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMK 851 +LG GAF++V+ Q + F LK K + + + LK + Sbjct: 28 VLGSGAFSEVFLVKQ-----RLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVT 82 Query: 852 FYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDC 911 + LV +L S G L + I EK LVI ++L ++ +H+ Sbjct: 83 LEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK--DASLVIQ---QVLSAVKYLHEN 137 Query: 912 EIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGF 971 I+H D+KP+N + +L ++ ++ + + D G S K+ G + TA C T G+ Sbjct: 138 GIVHRDLKPENLL----YLTPEE----NSKIMITDFGLS---KMEQNGIMSTA-CGTPGY 185 Query: 972 QCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 E+L+ KP++ +D + + Y +L G Sbjct: 186 VAPEVLAQKPYSKAVDCWSIGVITYILLCG 215 >gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] Length = 365 Score = 45.4 bits (106), Expect = 3e-04 Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 14/153 (9%) Query: 777 KTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFV-LKVQKPANPWEFYIGT 835 K EF +G K V + G G+F +Y A +N ++ V L+ QK +P Y + Sbjct: 8 KAEFIVGGKYKLVRKI-GSGSFGDIYLA----INITNGEEVAVKLESQKARHPQLLY-ES 61 Query: 836 QLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVI 895 +L + L+ + +++Y N VLV +L L ++ N + V+ Sbjct: 62 KLYKILQGGVGIPHIRWYGQEKDYN--VLVMDL-----LGPSLEDLFNFCSRRFTMKTVL 114 Query: 896 SFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNG 928 A +M+ IE VH IH DIKPDNF++G G Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147 >gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] Length = 337 Score = 45.4 bits (106), Expect = 3e-04 Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 14/153 (9%) Query: 777 KTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFV-LKVQKPANPWEFYIGT 835 K EF +G K V + G G+F +Y A +N ++ V L+ QK +P Y + Sbjct: 8 KAEFIVGGKYKLVRKI-GSGSFGDIYLA----INITNGEEVAVKLESQKARHPQLLY-ES 61 Query: 836 QLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVI 895 +L + L+ + +++Y N VLV +L L ++ N + V+ Sbjct: 62 KLYKILQGGVGIPHIRWYGQEKDYN--VLVMDL-----LGPSLEDLFNFCSRRFTMKTVL 114 Query: 896 SFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNG 928 A +M+ IE VH IH DIKPDNF++G G Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147 >gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens] Length = 590 Score = 45.4 bits (106), Expect = 3e-04 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 14/105 (13%) Query: 897 FAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLF 956 +A +L +E +H ++ D+KP+N +L D + + DLG ++ + Sbjct: 291 YAAEILCGLEDLHRENTVYRDLKPENILL-----------DDYGHIRISDLGLAVKI--- 336 Query: 957 PKGTIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 P+G + + T G+ E+L+N+ + DY+G+ +Y M+ G Sbjct: 337 PEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEG 381 >gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a [Homo sapiens] Length = 802 Score = 44.3 bits (103), Expect = 6e-04 Identities = 52/213 (24%), Positives = 88/213 (41%), Gaps = 30/213 (14%) Query: 793 LGEGAFAQVYEATQGDLNDAKNKQKFVLKV---QKPANPWEFYIGTQLMERLKPSMQHMF 849 LGEG+F+ + K+ Q F +K+ + AN + +L E P++ + Sbjct: 432 LGEGSFSICRKCVH-----KKSNQAFAVKIISKRMEANTQKEITALKLCEG-HPNIVKLH 485 Query: 850 MKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYM-IEQV 908 F+ Q + LV EL + G L I K+ E S+ MR L + + Sbjct: 486 EVFHD----QLHTFLVMELLNGGELFERIKKKKHFSETEA------SYIMRKLVSAVSHM 535 Query: 909 HDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCET 968 HD ++H D+KP+N + D+ D+L + +ID G P C T Sbjct: 536 HDVGVVHRDLKPENLLF------TDENDNLE--IKIIDFG--FARLKPPDNQPLKTPCFT 585 Query: 969 SGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 + E+L+ ++ D + + +Y ML G Sbjct: 586 LHYAAPELLNQNGYDESCDLWSLGVILYTMLSG 618 >gi|4507831 Unc-51-like kinase 1 [Homo sapiens] Length = 1050 Score = 43.9 bits (102), Expect = 8e-04 Identities = 48/211 (22%), Positives = 90/211 (42%), Gaps = 15/211 (7%) Query: 792 LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMK 851 L+G GAFA V++ + +D + K + K K + +G ++ + LK + Sbjct: 21 LIGHGAFAVVFKGRHREKHDLEVAVKCINK--KNLAKSQTLLGKEI-KILKELKHENIVA 77 Query: 852 FYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLV-ISFAMRMLYMIEQVHD 910 Y N LV E + G L + ++ + E + L I+ AMR+L H Sbjct: 78 LYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLL------HS 131 Query: 911 CEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSG 970 IIH D+KP N +L N + + + + +A D G + + + C + Sbjct: 132 KGIIHRDLKPQNILLSNPAGRRANPNSIRVKIA--DFGFA---RYLQSNMMAATLCGSPM 186 Query: 971 FQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001 + E++ ++ ++ + D + + VY L G Sbjct: 187 YMAPEVIMSQHYDGKADLWSIGTIVYQCLTG 217 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.131 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,121,611 Number of Sequences: 37866 Number of extensions: 2055713 Number of successful extensions: 8133 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 84 Number of HSP's successfully gapped in prelim test: 403 Number of HSP's that attempted gapping in prelim test: 7530 Number of HSP's gapped (non-prelim): 874 length of query: 1085 length of database: 18,247,518 effective HSP length: 113 effective length of query: 972 effective length of database: 13,968,660 effective search space: 13577537520 effective search space used: 13577537520 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.