Guide to the Human Genome
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Search of human proteins with 4757878

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4757878 budding uninhibited by benzimidazoles 1 [Homo
sapiens]
         (1085 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens]    2206   0.0  
gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s...   119   2e-26
gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa...    57   9e-08
gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regula...    54   6e-07
gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regula...    54   6e-07
gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regula...    54   6e-07
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula...    54   6e-07
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula...    54   6e-07
gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat...    53   2e-06
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...    52   2e-06
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...    52   2e-06
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...    52   4e-06
gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens]            51   5e-06
gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]           51   5e-06
gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]           51   5e-06
gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens]            49   2e-05
gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens]             49   2e-05
gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens]         49   3e-05
gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat...    49   3e-05
gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat...    49   3e-05
gi|4506529 rhodopsin kinase [Homo sapiens]                             48   4e-05
gi|217330634 serine/threonine kinase 36 [Homo sapiens]                 47   7e-05
gi|23943882 serine/threonine kinase 33 [Homo sapiens]                  47   1e-04
gi|32698688 citron [Homo sapiens]                                      47   1e-04
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo...    47   1e-04
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]          45   3e-04
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]          45   3e-04
gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]          45   3e-04
gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a...    44   6e-04
gi|4507831 Unc-51-like kinase 1 [Homo sapiens]                         44   8e-04

>gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens]
          Length = 1085

 Score = 2206 bits (5716), Expect = 0.0
 Identities = 1085/1085 (100%), Positives = 1085/1085 (100%)

Query: 1    MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 60
            MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK
Sbjct: 1    MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 60

Query: 61   KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 120
            KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
Sbjct: 61   KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 120

Query: 121  VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 180
            VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
Sbjct: 121  VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 180

Query: 181  NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 240
            NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
Sbjct: 181  NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 240

Query: 241  KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 300
            KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
Sbjct: 241  KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 300

Query: 301  HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 360
            HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
Sbjct: 301  HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 360

Query: 361  VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 420
            VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
Sbjct: 361  VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 420

Query: 421  AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 480
            AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
Sbjct: 421  AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 480

Query: 481  PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 540
            PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
Sbjct: 481  PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 540

Query: 541  PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 600
            PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
Sbjct: 541  PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 600

Query: 601  TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 660
            TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
Sbjct: 601  TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 660

Query: 661  SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 720
            SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
Sbjct: 661  SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 720

Query: 721  EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 780
            EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
Sbjct: 721  EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 780

Query: 781  QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 840
            QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
Sbjct: 781  QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 840

Query: 841  LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 900
            LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR
Sbjct: 841  LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 900

Query: 901  MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 960
            MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT
Sbjct: 901  MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 960

Query: 961  IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 1020
            IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
Sbjct: 961  IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 1020

Query: 1021 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1080
            RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
Sbjct: 1021 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1080

Query: 1081 KRSRK 1085
            KRSRK
Sbjct: 1081 KRSRK 1085


>gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
           sapiens]
          Length = 1050

 Score =  119 bits (298), Expect = 2e-26
 Identities = 59/161 (36%), Positives = 93/161 (57%), Gaps = 2/161 (1%)

Query: 2   DTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPEN--KEYLITLLEHLMKEFLDK 59
           +T +   +  E  ++ Y GNDPL  W+RYI W E+N+P+   +  + TLLE  ++    +
Sbjct: 53  NTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGE 112

Query: 60  KKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHAS 119
           K+Y++DPRF++  LK     ++    + +L+N GIG   +  YI+WA   EA+   + A 
Sbjct: 113 KRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKAD 172

Query: 120 AVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSE 160
           A+ Q GIQ +AEP E LQ Q+R FQ R++   L A  +  E
Sbjct: 173 AIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEE 213



 Score =  112 bits (280), Expect = 2e-24
 Identities = 123/514 (23%), Positives = 223/514 (43%), Gaps = 74/514 (14%)

Query: 567  EEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFHK------LPVESVH 620
            +E    E   +D+ + G R N T+ P+P+   DF  AA+  STPFH+      LP +   
Sbjct: 579  DEFTGIEPLSEDAIITGFR-NVTICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPER 637

Query: 621  ILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYSASLLRLSQ 680
            +L +++  V     Q T      +  +  +  K SPI E S ++A  S  +S S   ++ 
Sbjct: 638  LLPEEDLDVKTSEDQQTACGTIYSQTLSIK--KLSPIIEDS-REATHSSGFSGSSASVAS 694

Query: 681  PAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQAEWMQMSSLGTVDAPNFIVGN 740
             ++   L    +L      LT+  +   E+P  +                          
Sbjct: 695  TSSIKCLQIPEKL-----ELTNETS---ENPTQS-------------------------- 720

Query: 741  PWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQ 800
            PW  +   +LL  L +  +S     E +  +P ++ + E +LG++   +     E    +
Sbjct: 721  PWCSQYRRQLLKSLPELSASAELCIEDR-PMPKLEIEKEIELGNEDYCIKR---EYLICE 776

Query: 801  VYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQN 860
             Y+     +    + +  V+KV     PW+FYI  +L ERL     H    F S + +Q+
Sbjct: 777  DYKLFW--VAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDH----FCSCYQYQD 830

Query: 861  GSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKP 920
            G ++  +  +  TL + +        + +   + +     +L ++E +H  EI+HGD+ P
Sbjct: 831  GCIVWHQYINCFTLQDLLQ-----HSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSP 885

Query: 921  DNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEML--- 977
               IL N   +  D +  +  L ++D   S+D+++  +  +FT     SGF+ V++L   
Sbjct: 886  RCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRV--QLDVFTL----SGFRTVQILEGQ 939

Query: 978  ---SNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLDMWNEFFHV 1034
               +N    YQ+D FG+A   + +LF  +++V  +G   K       L   ++WN+FF  
Sbjct: 940  KILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVR 999

Query: 1035 MLNIPDCHHLPSLDLLRQKLKKVFQ---QHYTNK 1065
            +LN  D   +  L  L  ++  VF    Q + NK
Sbjct: 1000 ILNANDEATVSVLGELAAEMNGVFDTTFQSHLNK 1033



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%)

Query: 221 VHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKE 280
           V S   +  + ++ +MYCKEK+  G  EFSFEE+RA+ + ++ K ++         KR E
Sbjct: 382 VQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAE 441

Query: 281 ANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERS 318
                   ++++++E+ KKL ++  T  E     QE +
Sbjct: 442 --------MQKQIEEMEKKLKEIQTTQQERTGDQQEET 471


>gi|7657214 hormonally upregulated Neu-associated kinase [Homo
            sapiens]
          Length = 714

 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 53/215 (24%), Positives = 93/215 (43%), Gaps = 27/215 (12%)

Query: 793  LGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKF 852
            LGEG+FA+V E     L+    ++  +  + K     + Y+   L  R +  +Q M    
Sbjct: 68   LGEGSFAKVREG----LHVLTGEKVAIKVIDKKRAKKDTYVTKNL--RREGQIQQMIRHP 121

Query: 853  YSAHLF-----QNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQ 907
                L      +N   LV EL   G L++ I   K   E    +     +  +++  +E 
Sbjct: 122  NITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARR-----YIRQLISAVEH 176

Query: 908  VHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCE 967
            +H   ++H D+K +N +L        DED+    + LID G S    +      F+ +C 
Sbjct: 177  LHRAGVVHRDLKIENLLL--------DEDN---NIKLIDFGLSNCAGILGYSDPFSTQCG 225

Query: 968  TSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGT 1002
            +  +   E+L+ K +  +ID + +   +Y ML GT
Sbjct: 226  SPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGT 260


>gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1A isoform 5 [Homo sapiens]
          Length = 529

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
            +  L+G+G+F QV +A      D   ++   +K+ K  N   F    Q+  RL   M   
Sbjct: 161  IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV E+ SY    N  +L +NT  + +   L   FA +M
Sbjct: 214  DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 270  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
                   ++  ++  E+L   P++  ID + +   +  M  G              E LF
Sbjct: 316  QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361

Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
                 +D  N+   V L IP  H L      R+  +K+
Sbjct: 362  SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398


>gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1A isoform 4 [Homo sapiens]
          Length = 540

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
            +  L+G+G+F QV +A      D   ++   +K+ K  N   F    Q+  RL   M   
Sbjct: 161  IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV E+ SY    N  +L +NT  + +   L   FA +M
Sbjct: 214  DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 270  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
                   ++  ++  E+L   P++  ID + +   +  M  G              E LF
Sbjct: 316  QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361

Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
                 +D  N+   V L IP  H L      R+  +K+
Sbjct: 362  SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398


>gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1A isoform 3 [Homo sapiens]
          Length = 584

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
            +  L+G+G+F QV +A      D   ++   +K+ K  N   F    Q+  RL   M   
Sbjct: 161  IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV E+ SY    N  +L +NT  + +   L   FA +M
Sbjct: 214  DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 270  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
                   ++  ++  E+L   P++  ID + +   +  M  G              E LF
Sbjct: 316  QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361

Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
                 +D  N+   V L IP  H L      R+  +K+
Sbjct: 362  SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398


>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1A isoform 2 [Homo sapiens]
          Length = 754

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
            +  L+G+G+F QV +A      D   ++   +K+ K  N   F    Q+  RL   M   
Sbjct: 152  IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 204

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV E+ SY    N  +L +NT  + +   L   FA +M
Sbjct: 205  DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 260

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 261  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 306

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
                   ++  ++  E+L   P++  ID + +   +  M  G              E LF
Sbjct: 307  QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 352

Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
                 +D  N+   V L IP  H L      R+  +K+
Sbjct: 353  SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 389


>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1A isoform 1 [Homo sapiens]
          Length = 763

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
            +  L+G+G+F QV +A      D   ++   +K+ K  N   F    Q+  RL   M   
Sbjct: 161  IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV E+ SY    N  +L +NT  + +   L   FA +M
Sbjct: 214  DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 270  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
                   ++  ++  E+L   P++  ID + +   +  M  G              E LF
Sbjct: 316  QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361

Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
                 +D  N+   V L IP  H L      R+  +K+
Sbjct: 362  SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398


>gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1B isoform b [Homo sapiens]
          Length = 589

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 74/301 (24%), Positives = 124/301 (41%), Gaps = 50/301 (16%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847
            +  L+G+G+F QV +A      D + ++   +K+ K  N   F    Q+  RL   M QH
Sbjct: 113  IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV EL SY    N  +L +NT  + +   L    A ++
Sbjct: 166  DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 222  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
                   ++  ++  E+L   P++  ID + +   +  M  G              E LF
Sbjct: 268  QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG--------------EPLF 313

Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYT-NKIRALRNRLIVLLL 1078
                 +D  N    V L IP    L      R+  +++    +T  + + LR  L++ +L
Sbjct: 314  SGSNEVDQMNRIVEV-LGIPPAAMLDQAPKARKYFERLPGGGWTLRRTKELRKDLVLRML 372

Query: 1079 E 1079
            E
Sbjct: 373  E 373


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
            [Homo sapiens]
          Length = 357

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 26/220 (11%)

Query: 785  KLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERL 841
            K+      LG GAF++V    E   G L   K   K  LK ++ +   E  +  ++    
Sbjct: 21   KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHEN 80

Query: 842  KPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
              +++ ++      HL+     LV +L S G L + I       EK        +   ++
Sbjct: 81   IVALEDIYES--PNHLY-----LVMQLVSGGELFDRIVEKGFYTEKDAS-----TLIRQV 128

Query: 902  LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961
            L  +  +H   I+H D+KP+N +    +  QD+E  +     + D G S   K+  KG +
Sbjct: 129  LDAVYYLHRMGIVHRDLKPENLL----YYSQDEESKIM----ISDFGLS---KMEGKGDV 177

Query: 962  FTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
             +  C T G+   E+L+ KP++  +D + +    Y +L G
Sbjct: 178  MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCG 217


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2
            [Homo sapiens]
          Length = 385

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 26/220 (11%)

Query: 785  KLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERL 841
            K+      LG GAF++V    E   G L   K   K  LK ++ +   E  +  ++    
Sbjct: 21   KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHEN 80

Query: 842  KPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
              +++ ++      HL+     LV +L S G L + I       EK        +   ++
Sbjct: 81   IVALEDIYES--PNHLY-----LVMQLVSGGELFDRIVEKGFYTEKDAS-----TLIRQV 128

Query: 902  LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961
            L  +  +H   I+H D+KP+N +    +  QD+E  +     + D G S   K+  KG +
Sbjct: 129  LDAVYYLHRMGIVHRDLKPENLL----YYSQDEESKIM----ISDFGLS---KMEGKGDV 177

Query: 962  FTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
             +  C T G+   E+L+ KP++  +D + +    Y +L G
Sbjct: 178  MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCG 217


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
            sapiens]
          Length = 370

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 12/137 (8%)

Query: 866  GELYSYGTLLNAINLYKNTPEK-VMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNFI 924
            G LY    L++   L+    EK    +        ++L  ++ +HD  I+H D+KP+N +
Sbjct: 89   GHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLL 148

Query: 925  LGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWNY 984
              +  L++D +      + + D G S   K+   G++ +  C T G+   E+L+ KP++ 
Sbjct: 149  YYS--LDEDSK------IMISDFGLS---KMEDPGSVLSTACGTPGYVAPEVLAQKPYSK 197

Query: 985  QIDYFGVAATVYCMLFG 1001
             +D + +    Y +L G
Sbjct: 198  AVDCWSIGVIAYILLCG 214


>gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens]
          Length = 470

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%)

Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808
           K +SG S  +S+YP T                 L ++   +   LG G+F  VY      
Sbjct: 9   KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45

Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863
           ++D K K+   LKV K  +  E      +   L  +L   + H   +KF+++ + Q+   
Sbjct: 46  VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105

Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923
           ++ E      L + I  YK    K+ P+  +I + +++L  ++ +H+  I+H D+K  N 
Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164

Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983
            L N  L+  D      G++ + +G S D+         T    T  +   E L ++ ++
Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210

Query: 984 YQIDYFGVAATVYCM 998
            + D + +A  +Y M
Sbjct: 211 TKSDIWSLACILYEM 225


>gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]
          Length = 599

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%)

Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808
           K +SG S  +S+YP T                 L ++   +   LG G+F  VY      
Sbjct: 9   KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45

Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863
           ++D K K+   LKV K  +  E      +   L  +L   + H   +KF+++ + Q+   
Sbjct: 46  VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105

Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923
           ++ E      L + I  YK    K+ P+  +I + +++L  ++ +H+  I+H D+K  N 
Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164

Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983
            L N  L+  D      G++ + +G S D+         T    T  +   E L ++ ++
Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210

Query: 984 YQIDYFGVAATVYCM 998
            + D + +A  +Y M
Sbjct: 211 TKSDIWSLACILYEM 225


>gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]
          Length = 645

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%)

Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808
           K +SG S  +S+YP T                 L ++   +   LG G+F  VY      
Sbjct: 9   KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45

Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863
           ++D K K+   LKV K  +  E      +   L  +L   + H   +KF+++ + Q+   
Sbjct: 46  VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105

Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923
           ++ E      L + I  YK    K+ P+  +I + +++L  ++ +H+  I+H D+K  N 
Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164

Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983
            L N  L+  D      G++ + +G S D+         T    T  +   E L ++ ++
Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210

Query: 984 YQIDYFGVAATVYCM 998
            + D + +A  +Y M
Sbjct: 211 TKSDIWSLACILYEM 225


>gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens]
          Length = 347

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 23/178 (12%)

Query: 761 YPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEAT---QGDLNDAKNKQK 817
           +PNT  ++C L       +FQ+  K+       G G F++VY+AT          K  Q 
Sbjct: 66  HPNTLSFRCSL------ADFQIEKKI-------GRGQFSEVYKATCLLDRKTVALKKVQI 112

Query: 818 FVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNA 877
           F +   K        IG      LK       +K+  + +  N   +V EL   G L   
Sbjct: 113 FEMMDAKARQDCVKEIGL-----LKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQM 167

Query: 878 INLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDN-FILGNGFLEQDD 934
           I  +K   ++++P+  V  + +++   +E +H   ++H DIKP N FI   G ++  D
Sbjct: 168 IKYFKKQ-KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGD 224


>gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens]
          Length = 313

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 23/178 (12%)

Query: 761 YPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEAT---QGDLNDAKNKQK 817
           +PNT  ++C L       +FQ+  K+       G G F++VY+AT          K  Q 
Sbjct: 32  HPNTLSFRCSL------ADFQIEKKI-------GRGQFSEVYKATCLLDRKTVALKKVQI 78

Query: 818 FVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNA 877
           F +   K        IG      LK       +K+  + +  N   +V EL   G L   
Sbjct: 79  FEMMDAKARQDCVKEIGL-----LKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQM 133

Query: 878 INLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDN-FILGNGFLEQDD 934
           I  +K   ++++P+  V  + +++   +E +H   ++H DIKP N FI   G ++  D
Sbjct: 134 IKYFKKQ-KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGD 190


>gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens]
          Length = 553

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 54/221 (24%), Positives = 97/221 (43%), Gaps = 40/221 (18%)

Query: 792  LLGEGAFAQVYEA---TQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLK-PSMQH 847
            +LG+G F +V        G +   K   K  LK  K        +  +++E++  P +  
Sbjct: 196  VLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLK--KKGGEKMALLEKEILEKVSSPFIVS 253

Query: 848  MFMKFYS-AHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
            +   F S  HL       NG  L   +Y+ GT             + +    VI ++ ++
Sbjct: 254  LAYAFESKTHLCLVMSLMNGGDLKFHIYNVGT-------------RGLDMSRVIFYSAQI 300

Query: 902  LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961
               +  +H+  I++ D+KP+N +L          DDL     L DLG +++MK    G  
Sbjct: 301  ACGMLHLHELGIVYRDMKPENVLL----------DDL-GNCRLSDLGLAVEMK---GGKP 346

Query: 962  FTAKCETSGFQCVEMLSNK-PWNYQIDYFGVAATVYCMLFG 1001
             T +  T+G+   E+L  K  ++Y +D+F +  ++Y M+ G
Sbjct: 347  ITQRAGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAG 387


>gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1B isoform a [Homo sapiens]
          Length = 629

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847
            +  L+G+G+F QV +A      D + ++   +K+ K  N   F    Q+  RL   M QH
Sbjct: 113  IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV EL SY    N  +L +NT  + +   L    A ++
Sbjct: 166  DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 222  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
                   ++  ++  E+L   P++  ID + +   +  M  G
Sbjct: 268  QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG 309


>gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated
            kinase 1B isoform c [Homo sapiens]
          Length = 601

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)

Query: 789  VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847
            +  L+G+G+F QV +A      D + ++   +K+ K  N   F    Q+  RL   M QH
Sbjct: 113  IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165

Query: 848  -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
               MK+Y  HL     F+N   LV EL SY    N  +L +NT  + +   L    A ++
Sbjct: 166  DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221

Query: 902  L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
                +     +  IIH D+KP+N +L N            + + ++D G S  +     G
Sbjct: 222  CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267

Query: 960  TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
                   ++  ++  E+L   P++  ID + +   +  M  G
Sbjct: 268  QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG 309


>gi|4506529 rhodopsin kinase [Homo sapiens]
          Length = 563

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 47/216 (21%), Positives = 93/216 (43%), Gaps = 32/216 (14%)

Query: 792 LLGEGAFAQVYEATQ---GDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHM 848
           +LG+G F +V        G L   K   K  LK +K       Y G  + +++   +   
Sbjct: 195 VLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKG------YQGAMVEKKILMKVHSR 248

Query: 849 FMKFYSAHLFQNGSVLVGELYSYGTLLNA----INLYK-NTPEKVMPQGLVISFAMRMLY 903
           F+    A+ F+  +    +L    T++N      ++Y  N      P+   + +  +++ 
Sbjct: 249 FIVSL-AYAFETKA----DLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIIC 303

Query: 904 MIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFT 963
            +E +H   I++ D+KP+N +L N              + + DLG ++++      T   
Sbjct: 304 GLEHLHQRRIVYRDLKPENVLLDN-----------DGNVRISDLGLAVELLDGQSKT--K 350

Query: 964 AKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCML 999
               T GF   E+L  + +++ +DYF +  T+Y M+
Sbjct: 351 GYAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMI 386


>gi|217330634 serine/threonine kinase 36 [Homo sapiens]
          Length = 1315

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 47/217 (21%), Positives = 94/217 (43%), Gaps = 26/217 (11%)

Query: 788  YVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWE-FYIGTQLMERLK-PSM 845
            +V  ++GEG+F +VY+  +   +      KF+ K+ +            ++M  L+ P++
Sbjct: 5    HVLEMIGEGSFGRVYKGRR-KYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNI 63

Query: 846  QHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMI 905
             HM   F +     +  V+V   Y+ G L   +       +  +P+  V + A +++  +
Sbjct: 64   VHMLDSFET-----DKEVVVVTDYAEGELFQILE-----DDGKLPEDQVQAIAAQLVSAL 113

Query: 906  EQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAK 965
              +H   I+H D+KP N +L  G            G+ L D G +  M       + T+ 
Sbjct: 114  YYLHSHRILHRDMKPQNILLAKG-----------GGIKLCDFGFARAMS--TNTMVLTSI 160

Query: 966  CETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGT 1002
              T  +   E++  +P+++  D + V   +Y +  GT
Sbjct: 161  KGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGT 197


>gi|23943882 serine/threonine kinase 33 [Homo sapiens]
          Length = 514

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 48/215 (22%), Positives = 100/215 (46%), Gaps = 21/215 (9%)

Query: 792  LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER---LKPSMQHM 848
            +LG+G+F  V EAT     D + + K+ +K           +  +L+ER   +  S++H 
Sbjct: 121  ILGKGSFGIVIEAT-----DKETETKWAIKKVNKEKAGSSAV--KLLEREVNILKSVKHE 173

Query: 849  FMKFYSAHLFQNGS--VLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIE 906
             +  +   +F+      LV EL   G L   ++   +  E    + ++ S A  + Y+  
Sbjct: 174  HI-IHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENET-RWIIQSLASAIAYL-- 229

Query: 907  QVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKC 966
              H+ +I+H D+K +N ++ +  +  DD ++++  + + D G ++  K      +  A C
Sbjct: 230  --HNNDIVHRDLKLENIMVKSSLI--DDNNEINLNIKVTDFGLAV-KKQSRSEAMLQATC 284

Query: 967  ETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
             T  +   E++S   ++ Q D + +   +Y +L G
Sbjct: 285  GTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRG 319


>gi|32698688 citron [Homo sapiens]
          Length = 2027

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 38/236 (16%)

Query: 779  EFQLGSKLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFY--I 833
            E Q  +K   V  L+G G FA+V    E   GD+   K  +K  L  Q+  + +E    I
Sbjct: 89   ELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNI 148

Query: 834  GTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGL 893
             ++      P +Q+ F         +N   LV E    G LL+ +N Y    E  + + L
Sbjct: 149  LSRSTSPWIPQLQYAFQD-------KNHLYLVMEYQPGGDLLSLLNRY----EDQLDENL 197

Query: 894  VISFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDM 953
            +  +   ++  +  VH    +H DIKP+N ++           D +  + L+D G +  M
Sbjct: 198  IQFYLAELILAVHSVHLMGYVHRDIKPENILV-----------DRTGHIKLVDFGSAAKM 246

Query: 954  KLFPKGTIFTAKCE--TSGFQCVEMLS------NKPWNYQIDYFGVAATVYCMLFG 1001
                   +  AK    T  +   E+L+         +    D++ V    Y M++G
Sbjct: 247  N---SNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYG 299



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 43/215 (20%), Positives = 93/215 (43%), Gaps = 37/215 (17%)

Query: 108 HLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQV 167
           H EAQ   QH    L++  Q+  E  + L  Q +                  + L + + 
Sbjct: 700 HREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIK------------------KDLADKET 741

Query: 168 LNQMITSKSNPGNNMACISKNQGSELSGVISSACDKESNMERRVITISKS-EYSVHSSLA 226
           L  M+       +    I     SE   +I++   K  ++E+R++ +S++ + + +SSL 
Sbjct: 742 LENMMQRHEEEAHEKGKIL----SEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLF 797

Query: 227 SKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEE 286
           ++ +     M  +E++I         ELR QK+    +  +   ++R   ++ E  + ++
Sbjct: 798 TQRN-----MKAQEEMI--------SELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQD 844

Query: 287 QLLKQKMDELHKKLHQV-VETSHEDLPASQERSEV 320
              K ++ EL  +L +V +E   + L   ++ +E+
Sbjct: 845 HSDKNRLLELETRLREVSLEHEEQKLELKRQLTEL 879


>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
            sapiens]
          Length = 476

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 52/210 (24%), Positives = 92/210 (43%), Gaps = 22/210 (10%)

Query: 792  LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMK 851
            +LG GAF++V+   Q         + F LK  K +  +        +  LK       + 
Sbjct: 28   VLGSGAFSEVFLVKQ-----RLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVT 82

Query: 852  FYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDC 911
                +       LV +L S G L + I       EK     LVI    ++L  ++ +H+ 
Sbjct: 83   LEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK--DASLVIQ---QVLSAVKYLHEN 137

Query: 912  EIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGF 971
             I+H D+KP+N +    +L  ++    ++ + + D G S   K+   G + TA C T G+
Sbjct: 138  GIVHRDLKPENLL----YLTPEE----NSKIMITDFGLS---KMEQNGIMSTA-CGTPGY 185

Query: 972  QCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
               E+L+ KP++  +D + +    Y +L G
Sbjct: 186  VAPEVLAQKPYSKAVDCWSIGVITYILLCG 215


>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
          Length = 365

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 14/153 (9%)

Query: 777 KTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFV-LKVQKPANPWEFYIGT 835
           K EF +G K   V  + G G+F  +Y A    +N    ++  V L+ QK  +P   Y  +
Sbjct: 8   KAEFIVGGKYKLVRKI-GSGSFGDIYLA----INITNGEEVAVKLESQKARHPQLLY-ES 61

Query: 836 QLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVI 895
           +L + L+  +    +++Y      N  VLV +L     L  ++    N   +      V+
Sbjct: 62  KLYKILQGGVGIPHIRWYGQEKDYN--VLVMDL-----LGPSLEDLFNFCSRRFTMKTVL 114

Query: 896 SFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNG 928
             A +M+  IE VH    IH DIKPDNF++G G
Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147


>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
          Length = 337

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 14/153 (9%)

Query: 777 KTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFV-LKVQKPANPWEFYIGT 835
           K EF +G K   V  + G G+F  +Y A    +N    ++  V L+ QK  +P   Y  +
Sbjct: 8   KAEFIVGGKYKLVRKI-GSGSFGDIYLA----INITNGEEVAVKLESQKARHPQLLY-ES 61

Query: 836 QLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVI 895
           +L + L+  +    +++Y      N  VLV +L     L  ++    N   +      V+
Sbjct: 62  KLYKILQGGVGIPHIRWYGQEKDYN--VLVMDL-----LGPSLEDLFNFCSRRFTMKTVL 114

Query: 896 SFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNG 928
             A +M+  IE VH    IH DIKPDNF++G G
Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147


>gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]
          Length = 590

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 14/105 (13%)

Query: 897  FAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLF 956
            +A  +L  +E +H    ++ D+KP+N +L           D    + + DLG ++ +   
Sbjct: 291  YAAEILCGLEDLHRENTVYRDLKPENILL-----------DDYGHIRISDLGLAVKI--- 336

Query: 957  PKGTIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
            P+G +   +  T G+   E+L+N+ +    DY+G+   +Y M+ G
Sbjct: 337  PEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEG 381


>gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a
            [Homo sapiens]
          Length = 802

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 52/213 (24%), Positives = 88/213 (41%), Gaps = 30/213 (14%)

Query: 793  LGEGAFAQVYEATQGDLNDAKNKQKFVLKV---QKPANPWEFYIGTQLMERLKPSMQHMF 849
            LGEG+F+   +         K+ Q F +K+   +  AN  +     +L E   P++  + 
Sbjct: 432  LGEGSFSICRKCVH-----KKSNQAFAVKIISKRMEANTQKEITALKLCEG-HPNIVKLH 485

Query: 850  MKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYM-IEQV 908
              F+     Q  + LV EL + G L   I   K+  E         S+ MR L   +  +
Sbjct: 486  EVFHD----QLHTFLVMELLNGGELFERIKKKKHFSETEA------SYIMRKLVSAVSHM 535

Query: 909  HDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCET 968
            HD  ++H D+KP+N +        D+ D+L   + +ID G        P        C T
Sbjct: 536  HDVGVVHRDLKPENLLF------TDENDNLE--IKIIDFG--FARLKPPDNQPLKTPCFT 585

Query: 969  SGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
              +   E+L+   ++   D + +   +Y ML G
Sbjct: 586  LHYAAPELLNQNGYDESCDLWSLGVILYTMLSG 618


>gi|4507831 Unc-51-like kinase 1 [Homo sapiens]
          Length = 1050

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 48/211 (22%), Positives = 90/211 (42%), Gaps = 15/211 (7%)

Query: 792  LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMK 851
            L+G GAFA V++    + +D +   K + K  K     +  +G ++ + LK       + 
Sbjct: 21   LIGHGAFAVVFKGRHREKHDLEVAVKCINK--KNLAKSQTLLGKEI-KILKELKHENIVA 77

Query: 852  FYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLV-ISFAMRMLYMIEQVHD 910
             Y      N   LV E  + G L + ++  +   E  +   L  I+ AMR+L      H 
Sbjct: 78   LYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLL------HS 131

Query: 911  CEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSG 970
              IIH D+KP N +L N    + + + +   +A  D G +   +      +    C +  
Sbjct: 132  KGIIHRDLKPQNILLSNPAGRRANPNSIRVKIA--DFGFA---RYLQSNMMAATLCGSPM 186

Query: 971  FQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
            +   E++ ++ ++ + D + +   VY  L G
Sbjct: 187  YMAPEVIMSQHYDGKADLWSIGTIVYQCLTG 217


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,121,611
Number of Sequences: 37866
Number of extensions: 2055713
Number of successful extensions: 8133
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 403
Number of HSP's that attempted gapping in prelim test: 7530
Number of HSP's gapped (non-prelim): 874
length of query: 1085
length of database: 18,247,518
effective HSP length: 113
effective length of query: 972
effective length of database: 13,968,660
effective search space: 13577537520
effective search space used: 13577537520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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