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Search of human proteins with 4757878
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757878 budding uninhibited by benzimidazoles 1 [Homo
sapiens]
(1085 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens] 2206 0.0
gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s... 119 2e-26
gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa... 57 9e-08
gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07
gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07
gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 54 6e-07
gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat... 53 2e-06
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 52 2e-06
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 52 2e-06
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 52 4e-06
gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens] 51 5e-06
gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens] 51 5e-06
gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens] 51 5e-06
gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens] 49 2e-05
gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens] 49 2e-05
gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens] 49 3e-05
gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat... 49 3e-05
gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat... 49 3e-05
gi|4506529 rhodopsin kinase [Homo sapiens] 48 4e-05
gi|217330634 serine/threonine kinase 36 [Homo sapiens] 47 7e-05
gi|23943882 serine/threonine kinase 33 [Homo sapiens] 47 1e-04
gi|32698688 citron [Homo sapiens] 47 1e-04
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 47 1e-04
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] 45 3e-04
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] 45 3e-04
gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens] 45 3e-04
gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a... 44 6e-04
gi|4507831 Unc-51-like kinase 1 [Homo sapiens] 44 8e-04
>gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens]
Length = 1085
Score = 2206 bits (5716), Expect = 0.0
Identities = 1085/1085 (100%), Positives = 1085/1085 (100%)
Query: 1 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 60
MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK
Sbjct: 1 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 60
Query: 61 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 120
KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
Sbjct: 61 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 120
Query: 121 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 180
VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
Sbjct: 121 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 180
Query: 181 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 240
NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
Sbjct: 181 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 240
Query: 241 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 300
KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
Sbjct: 241 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 300
Query: 301 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 360
HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
Sbjct: 301 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 360
Query: 361 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 420
VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
Sbjct: 361 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 420
Query: 421 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 480
AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
Sbjct: 421 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 480
Query: 481 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 540
PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
Sbjct: 481 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 540
Query: 541 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 600
PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
Sbjct: 541 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 600
Query: 601 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 660
TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
Sbjct: 601 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 660
Query: 661 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 720
SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
Sbjct: 661 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 720
Query: 721 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 780
EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
Sbjct: 721 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 780
Query: 781 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 840
QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
Sbjct: 781 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 840
Query: 841 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 900
LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR
Sbjct: 841 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 900
Query: 901 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 960
MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT
Sbjct: 901 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 960
Query: 961 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 1020
IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
Sbjct: 961 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 1020
Query: 1021 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1080
RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
Sbjct: 1021 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1080
Query: 1081 KRSRK 1085
KRSRK
Sbjct: 1081 KRSRK 1085
>gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
sapiens]
Length = 1050
Score = 119 bits (298), Expect = 2e-26
Identities = 59/161 (36%), Positives = 93/161 (57%), Gaps = 2/161 (1%)
Query: 2 DTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPEN--KEYLITLLEHLMKEFLDK 59
+T + + E ++ Y GNDPL W+RYI W E+N+P+ + + TLLE ++ +
Sbjct: 53 NTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGE 112
Query: 60 KKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHAS 119
K+Y++DPRF++ LK ++ + +L+N GIG + YI+WA EA+ + A
Sbjct: 113 KRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKAD 172
Query: 120 AVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSE 160
A+ Q GIQ +AEP E LQ Q+R FQ R++ L A + E
Sbjct: 173 AIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEE 213
Score = 112 bits (280), Expect = 2e-24
Identities = 123/514 (23%), Positives = 223/514 (43%), Gaps = 74/514 (14%)
Query: 567 EEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFHK------LPVESVH 620
+E E +D+ + G R N T+ P+P+ DF AA+ STPFH+ LP +
Sbjct: 579 DEFTGIEPLSEDAIITGFR-NVTICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPER 637
Query: 621 ILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYSASLLRLSQ 680
+L +++ V Q T + + + K SPI E S ++A S +S S ++
Sbjct: 638 LLPEEDLDVKTSEDQQTACGTIYSQTLSIK--KLSPIIEDS-REATHSSGFSGSSASVAS 694
Query: 681 PAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQAEWMQMSSLGTVDAPNFIVGN 740
++ L +L LT+ + E+P +
Sbjct: 695 TSSIKCLQIPEKL-----ELTNETS---ENPTQS-------------------------- 720
Query: 741 PWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQ 800
PW + +LL L + +S E + +P ++ + E +LG++ + E +
Sbjct: 721 PWCSQYRRQLLKSLPELSASAELCIEDR-PMPKLEIEKEIELGNEDYCIKR---EYLICE 776
Query: 801 VYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQN 860
Y+ + + + V+KV PW+FYI +L ERL H F S + +Q+
Sbjct: 777 DYKLFW--VAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDH----FCSCYQYQD 830
Query: 861 GSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKP 920
G ++ + + TL + + + + + + +L ++E +H EI+HGD+ P
Sbjct: 831 GCIVWHQYINCFTLQDLLQ-----HSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSP 885
Query: 921 DNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEML--- 977
IL N + D + + L ++D S+D+++ + +FT SGF+ V++L
Sbjct: 886 RCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRV--QLDVFTL----SGFRTVQILEGQ 939
Query: 978 ---SNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLDMWNEFFHV 1034
+N YQ+D FG+A + +LF +++V +G K L ++WN+FF
Sbjct: 940 KILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVR 999
Query: 1035 MLNIPDCHHLPSLDLLRQKLKKVFQ---QHYTNK 1065
+LN D + L L ++ VF Q + NK
Sbjct: 1000 ILNANDEATVSVLGELAAEMNGVFDTTFQSHLNK 1033
Score = 51.6 bits (122), Expect = 4e-06
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Query: 221 VHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKE 280
V S + + ++ +MYCKEK+ G EFSFEE+RA+ + ++ K ++ KR E
Sbjct: 382 VQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAE 441
Query: 281 ANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERS 318
++++++E+ KKL ++ T E QE +
Sbjct: 442 --------MQKQIEEMEKKLKEIQTTQQERTGDQQEET 471
>gi|7657214 hormonally upregulated Neu-associated kinase [Homo
sapiens]
Length = 714
Score = 57.0 bits (136), Expect = 9e-08
Identities = 53/215 (24%), Positives = 93/215 (43%), Gaps = 27/215 (12%)
Query: 793 LGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKF 852
LGEG+FA+V E L+ ++ + + K + Y+ L R + +Q M
Sbjct: 68 LGEGSFAKVREG----LHVLTGEKVAIKVIDKKRAKKDTYVTKNL--RREGQIQQMIRHP 121
Query: 853 YSAHLF-----QNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQ 907
L +N LV EL G L++ I K E + + +++ +E
Sbjct: 122 NITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARR-----YIRQLISAVEH 176
Query: 908 VHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCE 967
+H ++H D+K +N +L DED+ + LID G S + F+ +C
Sbjct: 177 LHRAGVVHRDLKIENLLL--------DEDN---NIKLIDFGLSNCAGILGYSDPFSTQCG 225
Query: 968 TSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGT 1002
+ + E+L+ K + +ID + + +Y ML GT
Sbjct: 226 SPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGT 260
>gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 5 [Homo sapiens]
Length = 529
Score = 54.3 bits (129), Expect = 6e-07
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
+ L+G+G+F QV +A D ++ +K+ K N F Q+ RL M
Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M
Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
++ ++ E+L P++ ID + + + M G E LF
Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361
Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
+D N+ V L IP H L R+ +K+
Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398
>gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 4 [Homo sapiens]
Length = 540
Score = 54.3 bits (129), Expect = 6e-07
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
+ L+G+G+F QV +A D ++ +K+ K N F Q+ RL M
Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M
Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
++ ++ E+L P++ ID + + + M G E LF
Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361
Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
+D N+ V L IP H L R+ +K+
Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398
>gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 3 [Homo sapiens]
Length = 584
Score = 54.3 bits (129), Expect = 6e-07
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
+ L+G+G+F QV +A D ++ +K+ K N F Q+ RL M
Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M
Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
++ ++ E+L P++ ID + + + M G E LF
Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361
Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
+D N+ V L IP H L R+ +K+
Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 54.3 bits (129), Expect = 6e-07
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
+ L+G+G+F QV +A D ++ +K+ K N F Q+ RL M
Sbjct: 152 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 204
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M
Sbjct: 205 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 260
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 261 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 306
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
++ ++ E+L P++ ID + + + M G E LF
Sbjct: 307 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 352
Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
+D N+ V L IP H L R+ +K+
Sbjct: 353 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 389
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 54.3 bits (129), Expect = 6e-07
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 49/278 (17%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH- 847
+ L+G+G+F QV +A D ++ +K+ K N F Q+ RL M
Sbjct: 161 IDSLIGKGSFGQVVKAY-----DRVEQEWVAIKIIK--NKKAFLNQAQIEVRLLELMNKH 213
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV E+ SY N +L +NT + + L FA +M
Sbjct: 214 DTEMKYYIVHLKRHFMFRNHLCLVFEMLSY----NLYDLLRNTNFRGVSLNLTRKFAQQM 269
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 270 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 315
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
++ ++ E+L P++ ID + + + M G E LF
Sbjct: 316 QRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTG--------------EPLF 361
Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKV 1057
+D N+ V L IP H L R+ +K+
Sbjct: 362 SGANEVDQMNKIVEV-LGIPPAHILDQAPKARKFFEKL 398
>gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform b [Homo sapiens]
Length = 589
Score = 52.8 bits (125), Expect = 2e-06
Identities = 74/301 (24%), Positives = 124/301 (41%), Gaps = 50/301 (16%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847
+ L+G+G+F QV +A D + ++ +K+ K N F Q+ RL M QH
Sbjct: 113 IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV EL SY N +L +NT + + L A ++
Sbjct: 166 DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 222 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLF 1019
++ ++ E+L P++ ID + + + M G E LF
Sbjct: 268 QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG--------------EPLF 313
Query: 1020 RRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYT-NKIRALRNRLIVLLL 1078
+D N V L IP L R+ +++ +T + + LR L++ +L
Sbjct: 314 SGSNEVDQMNRIVEV-LGIPPAAMLDQAPKARKYFERLPGGGWTLRRTKELRKDLVLRML 372
Query: 1079 E 1079
E
Sbjct: 373 E 373
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 52.4 bits (124), Expect = 2e-06
Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 26/220 (11%)
Query: 785 KLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERL 841
K+ LG GAF++V E G L K K LK ++ + E + ++
Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHEN 80
Query: 842 KPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
+++ ++ HL+ LV +L S G L + I EK + ++
Sbjct: 81 IVALEDIYES--PNHLY-----LVMQLVSGGELFDRIVEKGFYTEKDAS-----TLIRQV 128
Query: 902 LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961
L + +H I+H D+KP+N + + QD+E + + D G S K+ KG +
Sbjct: 129 LDAVYYLHRMGIVHRDLKPENLL----YYSQDEESKIM----ISDFGLS---KMEGKGDV 177
Query: 962 FTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
+ C T G+ E+L+ KP++ +D + + Y +L G
Sbjct: 178 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCG 217
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2
[Homo sapiens]
Length = 385
Score = 52.4 bits (124), Expect = 2e-06
Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 26/220 (11%)
Query: 785 KLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERL 841
K+ LG GAF++V E G L K K LK ++ + E + ++
Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHEN 80
Query: 842 KPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
+++ ++ HL+ LV +L S G L + I EK + ++
Sbjct: 81 IVALEDIYES--PNHLY-----LVMQLVSGGELFDRIVEKGFYTEKDAS-----TLIRQV 128
Query: 902 LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961
L + +H I+H D+KP+N + + QD+E + + D G S K+ KG +
Sbjct: 129 LDAVYYLHRMGIVHRDLKPENLL----YYSQDEESKIM----ISDFGLS---KMEGKGDV 177
Query: 962 FTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
+ C T G+ E+L+ KP++ +D + + Y +L G
Sbjct: 178 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCG 217
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 51.6 bits (122), Expect = 4e-06
Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 12/137 (8%)
Query: 866 GELYSYGTLLNAINLYKNTPEK-VMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNFI 924
G LY L++ L+ EK + ++L ++ +HD I+H D+KP+N +
Sbjct: 89 GHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLL 148
Query: 925 LGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWNY 984
+ L++D + + + D G S K+ G++ + C T G+ E+L+ KP++
Sbjct: 149 YYS--LDEDSK------IMISDFGLS---KMEDPGSVLSTACGTPGYVAPEVLAQKPYSK 197
Query: 985 QIDYFGVAATVYCMLFG 1001
+D + + Y +L G
Sbjct: 198 AVDCWSIGVIAYILLCG 214
>gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens]
Length = 470
Score = 51.2 bits (121), Expect = 5e-06
Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%)
Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808
K +SG S +S+YP T L ++ + LG G+F VY
Sbjct: 9 KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45
Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863
++D K K+ LKV K + E + L +L + H +KF+++ + Q+
Sbjct: 46 VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105
Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923
++ E L + I YK K+ P+ +I + +++L ++ +H+ I+H D+K N
Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164
Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983
L N L+ D G++ + +G S D+ T T + E L ++ ++
Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210
Query: 984 YQIDYFGVAATVYCM 998
+ D + +A +Y M
Sbjct: 211 TKSDIWSLACILYEM 225
>gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]
Length = 599
Score = 51.2 bits (121), Expect = 5e-06
Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%)
Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808
K +SG S +S+YP T L ++ + LG G+F VY
Sbjct: 9 KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45
Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863
++D K K+ LKV K + E + L +L + H +KF+++ + Q+
Sbjct: 46 VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105
Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923
++ E L + I YK K+ P+ +I + +++L ++ +H+ I+H D+K N
Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164
Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983
L N L+ D G++ + +G S D+ T T + E L ++ ++
Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210
Query: 984 YQIDYFGVAATVYCM 998
+ D + +A +Y M
Sbjct: 211 TKSDIWSLACILYEM 225
>gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]
Length = 645
Score = 51.2 bits (121), Expect = 5e-06
Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 43/255 (16%)
Query: 749 KLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGD 808
K +SG S +S+YP T L ++ + LG G+F VY
Sbjct: 9 KCVSG-STAISTYPKT-----------------LIARRYVLQQKLGSGSFGTVYL----- 45
Query: 809 LNDAKNKQKFVLKVQKPANPWEFY----IGTQLMERLKPSMQH-MFMKFYSAHLFQNGSV 863
++D K K+ LKV K + E + L +L + H +KF+++ + Q+
Sbjct: 46 VSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFC 105
Query: 864 LVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNF 923
++ E L + I YK K+ P+ +I + +++L ++ +H+ I+H D+K N
Sbjct: 106 IITEYCEGRDLDDKIQEYKQAG-KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNV 164
Query: 924 ILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWN 983
L N L+ D G++ + +G S D+ T T + E L ++ ++
Sbjct: 165 FLKNNLLKIGD-----FGVSRLLMG-SCDLA--------TTLTGTPHYMSPEALKHQGYD 210
Query: 984 YQIDYFGVAATVYCM 998
+ D + +A +Y M
Sbjct: 211 TKSDIWSLACILYEM 225
>gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens]
Length = 347
Score = 49.3 bits (116), Expect = 2e-05
Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 23/178 (12%)
Query: 761 YPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEAT---QGDLNDAKNKQK 817
+PNT ++C L +FQ+ K+ G G F++VY+AT K Q
Sbjct: 66 HPNTLSFRCSL------ADFQIEKKI-------GRGQFSEVYKATCLLDRKTVALKKVQI 112
Query: 818 FVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNA 877
F + K IG LK +K+ + + N +V EL G L
Sbjct: 113 FEMMDAKARQDCVKEIGL-----LKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQM 167
Query: 878 INLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDN-FILGNGFLEQDD 934
I +K ++++P+ V + +++ +E +H ++H DIKP N FI G ++ D
Sbjct: 168 IKYFKKQ-KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGD 224
>gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens]
Length = 313
Score = 49.3 bits (116), Expect = 2e-05
Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 23/178 (12%)
Query: 761 YPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEAT---QGDLNDAKNKQK 817
+PNT ++C L +FQ+ K+ G G F++VY+AT K Q
Sbjct: 32 HPNTLSFRCSL------ADFQIEKKI-------GRGQFSEVYKATCLLDRKTVALKKVQI 78
Query: 818 FVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNA 877
F + K IG LK +K+ + + N +V EL G L
Sbjct: 79 FEMMDAKARQDCVKEIGL-----LKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQM 133
Query: 878 INLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDN-FILGNGFLEQDD 934
I +K ++++P+ V + +++ +E +H ++H DIKP N FI G ++ D
Sbjct: 134 IKYFKKQ-KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGD 190
>gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens]
Length = 553
Score = 48.9 bits (115), Expect = 3e-05
Identities = 54/221 (24%), Positives = 97/221 (43%), Gaps = 40/221 (18%)
Query: 792 LLGEGAFAQVYEA---TQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLK-PSMQH 847
+LG+G F +V G + K K LK K + +++E++ P +
Sbjct: 196 VLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLK--KKGGEKMALLEKEILEKVSSPFIVS 253
Query: 848 MFMKFYS-AHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
+ F S HL NG L +Y+ GT + + VI ++ ++
Sbjct: 254 LAYAFESKTHLCLVMSLMNGGDLKFHIYNVGT-------------RGLDMSRVIFYSAQI 300
Query: 902 LYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTI 961
+ +H+ I++ D+KP+N +L DDL L DLG +++MK G
Sbjct: 301 ACGMLHLHELGIVYRDMKPENVLL----------DDL-GNCRLSDLGLAVEMK---GGKP 346
Query: 962 FTAKCETSGFQCVEMLSNK-PWNYQIDYFGVAATVYCMLFG 1001
T + T+G+ E+L K ++Y +D+F + ++Y M+ G
Sbjct: 347 ITQRAGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAG 387
>gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform a [Homo sapiens]
Length = 629
Score = 48.5 bits (114), Expect = 3e-05
Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847
+ L+G+G+F QV +A D + ++ +K+ K N F Q+ RL M QH
Sbjct: 113 IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV EL SY N +L +NT + + L A ++
Sbjct: 166 DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 222 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
++ ++ E+L P++ ID + + + M G
Sbjct: 268 QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG 309
>gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform c [Homo sapiens]
Length = 601
Score = 48.5 bits (114), Expect = 3e-05
Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)
Query: 789 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSM-QH 847
+ L+G+G+F QV +A D + ++ +K+ K N F Q+ RL M QH
Sbjct: 113 IDSLIGKGSFGQVVKAY-----DHQTQELVAIKIIK--NKKAFLNQAQIELRLLELMNQH 165
Query: 848 -MFMKFYSAHL-----FQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRM 901
MK+Y HL F+N LV EL SY N +L +NT + + L A ++
Sbjct: 166 DTEMKYYIVHLKRHFMFRNHLCLVFELLSY----NLYDLLRNTHFRGVSLNLTRKLAQQL 221
Query: 902 L--YMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKG 959
+ + IIH D+KP+N +L N + + ++D G S + G
Sbjct: 222 CTALLFLATPELSIIHCDLKPENILLCN---------PKRSAIKIVDFGSSCQL-----G 267
Query: 960 TIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
++ ++ E+L P++ ID + + + M G
Sbjct: 268 QRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTG 309
>gi|4506529 rhodopsin kinase [Homo sapiens]
Length = 563
Score = 48.1 bits (113), Expect = 4e-05
Identities = 47/216 (21%), Positives = 93/216 (43%), Gaps = 32/216 (14%)
Query: 792 LLGEGAFAQVYEATQ---GDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHM 848
+LG+G F +V G L K K LK +K Y G + +++ +
Sbjct: 195 VLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKG------YQGAMVEKKILMKVHSR 248
Query: 849 FMKFYSAHLFQNGSVLVGELYSYGTLLNA----INLYK-NTPEKVMPQGLVISFAMRMLY 903
F+ A+ F+ + +L T++N ++Y N P+ + + +++
Sbjct: 249 FIVSL-AYAFETKA----DLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIIC 303
Query: 904 MIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFT 963
+E +H I++ D+KP+N +L N + + DLG ++++ T
Sbjct: 304 GLEHLHQRRIVYRDLKPENVLLDN-----------DGNVRISDLGLAVELLDGQSKT--K 350
Query: 964 AKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCML 999
T GF E+L + +++ +DYF + T+Y M+
Sbjct: 351 GYAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMI 386
>gi|217330634 serine/threonine kinase 36 [Homo sapiens]
Length = 1315
Score = 47.4 bits (111), Expect = 7e-05
Identities = 47/217 (21%), Positives = 94/217 (43%), Gaps = 26/217 (11%)
Query: 788 YVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWE-FYIGTQLMERLK-PSM 845
+V ++GEG+F +VY+ + + KF+ K+ + ++M L+ P++
Sbjct: 5 HVLEMIGEGSFGRVYKGRR-KYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNI 63
Query: 846 QHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMI 905
HM F + + V+V Y+ G L + + +P+ V + A +++ +
Sbjct: 64 VHMLDSFET-----DKEVVVVTDYAEGELFQILE-----DDGKLPEDQVQAIAAQLVSAL 113
Query: 906 EQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAK 965
+H I+H D+KP N +L G G+ L D G + M + T+
Sbjct: 114 YYLHSHRILHRDMKPQNILLAKG-----------GGIKLCDFGFARAMS--TNTMVLTSI 160
Query: 966 CETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGT 1002
T + E++ +P+++ D + V +Y + GT
Sbjct: 161 KGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGT 197
>gi|23943882 serine/threonine kinase 33 [Homo sapiens]
Length = 514
Score = 47.0 bits (110), Expect = 1e-04
Identities = 48/215 (22%), Positives = 100/215 (46%), Gaps = 21/215 (9%)
Query: 792 LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER---LKPSMQHM 848
+LG+G+F V EAT D + + K+ +K + +L+ER + S++H
Sbjct: 121 ILGKGSFGIVIEAT-----DKETETKWAIKKVNKEKAGSSAV--KLLEREVNILKSVKHE 173
Query: 849 FMKFYSAHLFQNGS--VLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIE 906
+ + +F+ LV EL G L ++ + E + ++ S A + Y+
Sbjct: 174 HI-IHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENET-RWIIQSLASAIAYL-- 229
Query: 907 QVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKC 966
H+ +I+H D+K +N ++ + + DD ++++ + + D G ++ K + A C
Sbjct: 230 --HNNDIVHRDLKLENIMVKSSLI--DDNNEINLNIKVTDFGLAV-KKQSRSEAMLQATC 284
Query: 967 ETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
T + E++S ++ Q D + + +Y +L G
Sbjct: 285 GTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRG 319
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 46.6 bits (109), Expect = 1e-04
Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 38/236 (16%)
Query: 779 EFQLGSKLVYVHHLLGEGAFAQVY---EATQGDLNDAKNKQKFVLKVQKPANPWEFY--I 833
E Q +K V L+G G FA+V E GD+ K +K L Q+ + +E I
Sbjct: 89 ELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNI 148
Query: 834 GTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGL 893
++ P +Q+ F +N LV E G LL+ +N Y E + + L
Sbjct: 149 LSRSTSPWIPQLQYAFQD-------KNHLYLVMEYQPGGDLLSLLNRY----EDQLDENL 197
Query: 894 VISFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDM 953
+ + ++ + VH +H DIKP+N ++ D + + L+D G + M
Sbjct: 198 IQFYLAELILAVHSVHLMGYVHRDIKPENILV-----------DRTGHIKLVDFGSAAKM 246
Query: 954 KLFPKGTIFTAKCE--TSGFQCVEMLS------NKPWNYQIDYFGVAATVYCMLFG 1001
+ AK T + E+L+ + D++ V Y M++G
Sbjct: 247 N---SNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYG 299
Score = 30.8 bits (68), Expect = 7.3
Identities = 43/215 (20%), Positives = 93/215 (43%), Gaps = 37/215 (17%)
Query: 108 HLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQV 167
H EAQ QH L++ Q+ E + L Q + + L + +
Sbjct: 700 HREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIK------------------KDLADKET 741
Query: 168 LNQMITSKSNPGNNMACISKNQGSELSGVISSACDKESNMERRVITISKS-EYSVHSSLA 226
L M+ + I SE +I++ K ++E+R++ +S++ + + +SSL
Sbjct: 742 LENMMQRHEEEAHEKGKIL----SEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLF 797
Query: 227 SKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEE 286
++ + M +E++I ELR QK+ + + ++R ++ E + ++
Sbjct: 798 TQRN-----MKAQEEMI--------SELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQD 844
Query: 287 QLLKQKMDELHKKLHQV-VETSHEDLPASQERSEV 320
K ++ EL +L +V +E + L ++ +E+
Sbjct: 845 HSDKNRLLELETRLREVSLEHEEQKLELKRQLTEL 879
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 46.6 bits (109), Expect = 1e-04
Identities = 52/210 (24%), Positives = 92/210 (43%), Gaps = 22/210 (10%)
Query: 792 LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMK 851
+LG GAF++V+ Q + F LK K + + + LK +
Sbjct: 28 VLGSGAFSEVFLVKQ-----RLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVT 82
Query: 852 FYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDC 911
+ LV +L S G L + I EK LVI ++L ++ +H+
Sbjct: 83 LEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEK--DASLVIQ---QVLSAVKYLHEN 137
Query: 912 EIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGF 971
I+H D+KP+N + +L ++ ++ + + D G S K+ G + TA C T G+
Sbjct: 138 GIVHRDLKPENLL----YLTPEE----NSKIMITDFGLS---KMEQNGIMSTA-CGTPGY 185
Query: 972 QCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
E+L+ KP++ +D + + Y +L G
Sbjct: 186 VAPEVLAQKPYSKAVDCWSIGVITYILLCG 215
>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
Length = 365
Score = 45.4 bits (106), Expect = 3e-04
Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 777 KTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFV-LKVQKPANPWEFYIGT 835
K EF +G K V + G G+F +Y A +N ++ V L+ QK +P Y +
Sbjct: 8 KAEFIVGGKYKLVRKI-GSGSFGDIYLA----INITNGEEVAVKLESQKARHPQLLY-ES 61
Query: 836 QLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVI 895
+L + L+ + +++Y N VLV +L L ++ N + V+
Sbjct: 62 KLYKILQGGVGIPHIRWYGQEKDYN--VLVMDL-----LGPSLEDLFNFCSRRFTMKTVL 114
Query: 896 SFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNG 928
A +M+ IE VH IH DIKPDNF++G G
Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147
>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
Length = 337
Score = 45.4 bits (106), Expect = 3e-04
Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 777 KTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFV-LKVQKPANPWEFYIGT 835
K EF +G K V + G G+F +Y A +N ++ V L+ QK +P Y +
Sbjct: 8 KAEFIVGGKYKLVRKI-GSGSFGDIYLA----INITNGEEVAVKLESQKARHPQLLY-ES 61
Query: 836 QLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVI 895
+L + L+ + +++Y N VLV +L L ++ N + V+
Sbjct: 62 KLYKILQGGVGIPHIRWYGQEKDYN--VLVMDL-----LGPSLEDLFNFCSRRFTMKTVL 114
Query: 896 SFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNG 928
A +M+ IE VH IH DIKPDNF++G G
Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147
>gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]
Length = 590
Score = 45.4 bits (106), Expect = 3e-04
Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 14/105 (13%)
Query: 897 FAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLF 956
+A +L +E +H ++ D+KP+N +L D + + DLG ++ +
Sbjct: 291 YAAEILCGLEDLHRENTVYRDLKPENILL-----------DDYGHIRISDLGLAVKI--- 336
Query: 957 PKGTIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
P+G + + T G+ E+L+N+ + DY+G+ +Y M+ G
Sbjct: 337 PEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEG 381
>gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a
[Homo sapiens]
Length = 802
Score = 44.3 bits (103), Expect = 6e-04
Identities = 52/213 (24%), Positives = 88/213 (41%), Gaps = 30/213 (14%)
Query: 793 LGEGAFAQVYEATQGDLNDAKNKQKFVLKV---QKPANPWEFYIGTQLMERLKPSMQHMF 849
LGEG+F+ + K+ Q F +K+ + AN + +L E P++ +
Sbjct: 432 LGEGSFSICRKCVH-----KKSNQAFAVKIISKRMEANTQKEITALKLCEG-HPNIVKLH 485
Query: 850 MKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYM-IEQV 908
F+ Q + LV EL + G L I K+ E S+ MR L + +
Sbjct: 486 EVFHD----QLHTFLVMELLNGGELFERIKKKKHFSETEA------SYIMRKLVSAVSHM 535
Query: 909 HDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCET 968
HD ++H D+KP+N + D+ D+L + +ID G P C T
Sbjct: 536 HDVGVVHRDLKPENLLF------TDENDNLE--IKIIDFG--FARLKPPDNQPLKTPCFT 585
Query: 969 SGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
+ E+L+ ++ D + + +Y ML G
Sbjct: 586 LHYAAPELLNQNGYDESCDLWSLGVILYTMLSG 618
>gi|4507831 Unc-51-like kinase 1 [Homo sapiens]
Length = 1050
Score = 43.9 bits (102), Expect = 8e-04
Identities = 48/211 (22%), Positives = 90/211 (42%), Gaps = 15/211 (7%)
Query: 792 LLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMK 851
L+G GAFA V++ + +D + K + K K + +G ++ + LK +
Sbjct: 21 LIGHGAFAVVFKGRHREKHDLEVAVKCINK--KNLAKSQTLLGKEI-KILKELKHENIVA 77
Query: 852 FYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLV-ISFAMRMLYMIEQVHD 910
Y N LV E + G L + ++ + E + L I+ AMR+L H
Sbjct: 78 LYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLL------HS 131
Query: 911 CEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSG 970
IIH D+KP N +L N + + + + +A D G + + + C +
Sbjct: 132 KGIIHRDLKPQNILLSNPAGRRANPNSIRVKIA--DFGFA---RYLQSNMMAATLCGSPM 186
Query: 971 FQCVEMLSNKPWNYQIDYFGVAATVYCMLFG 1001
+ E++ ++ ++ + D + + VY L G
Sbjct: 187 YMAPEVIMSQHYDGKADLWSIGTIVYQCLTG 217
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,121,611
Number of Sequences: 37866
Number of extensions: 2055713
Number of successful extensions: 8133
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 403
Number of HSP's that attempted gapping in prelim test: 7530
Number of HSP's gapped (non-prelim): 874
length of query: 1085
length of database: 18,247,518
effective HSP length: 113
effective length of query: 972
effective length of database: 13,968,660
effective search space: 13577537520
effective search space used: 13577537520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.