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Search of human proteins with 47458043
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47458043 armadillo repeat containing 8 isoform 3 [Homo
sapiens]
(385 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47458043 armadillo repeat containing 8 isoform 3 [Homo sapiens] 760 0.0
gi|47458045 armadillo repeat containing 8 isoform 1 [Homo sapiens] 760 0.0
gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens] 722 0.0
gi|4504901 karyopherin alpha 4 [Homo sapiens] 45 1e-04
gi|222144293 karyopherin alpha 1 [Homo sapiens] 42 0.001
gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens] 41 0.002
gi|224589129 karyopherin 7 [Homo sapiens] 39 0.006
gi|4504897 karyopherin alpha 2 [Homo sapiens] 38 0.013
gi|6912478 karyopherin alpha 6 [Homo sapiens] 38 0.018
gi|39812229 karyopherin alpha 5 [Homo sapiens] 37 0.030
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens] 33 0.33
gi|34485722 karyopherin alpha 3 [Homo sapiens] 33 0.43
gi|189409124 armadillo repeat containing 3 [Homo sapiens] 33 0.57
gi|197333755 interferon-related developmental regulator 2 [Homo ... 33 0.57
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens] 31 1.6
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa... 31 1.6
gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5 [... 31 2.1
gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4 [... 31 2.1
gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3 [... 30 2.8
gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2 [... 30 2.8
gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1 [... 30 2.8
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 30 3.7
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] 30 3.7
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens] 30 3.7
gi|42558270 HEAT repeat containing 4 [Homo sapiens] 30 4.8
gi|154937380 hypothetical protein LOC642475 [Homo sapiens] 30 4.8
gi|31657114 armadillo repeat containing 4 [Homo sapiens] 29 6.3
gi|110349719 titin isoform N2-A [Homo sapiens] 29 8.2
gi|110349717 titin isoform novex-2 [Homo sapiens] 29 8.2
gi|110349713 titin isoform novex-1 [Homo sapiens] 29 8.2
>gi|47458043 armadillo repeat containing 8 isoform 3 [Homo sapiens]
Length = 385
Score = 760 bits (1963), Expect = 0.0
Identities = 385/385 (100%), Positives = 385/385 (100%)
Query: 1 MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET 60
MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET
Sbjct: 1 MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET 60
Query: 61 SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT 120
SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT
Sbjct: 61 SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT 120
Query: 121 SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA 180
SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA
Sbjct: 121 SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA 180
Query: 181 HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL 240
HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL
Sbjct: 181 HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL 240
Query: 241 TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL 300
TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL
Sbjct: 241 TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL 300
Query: 301 QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED 360
QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED
Sbjct: 301 QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED 360
Query: 361 IRKKVSLGEGRPPVLTASRQGVTST 385
IRKKVSLGEGRPPVLTASRQGVTST
Sbjct: 361 IRKKVSLGEGRPPVLTASRQGVTST 385
>gi|47458045 armadillo repeat containing 8 isoform 1 [Homo sapiens]
Length = 385
Score = 760 bits (1963), Expect = 0.0
Identities = 385/385 (100%), Positives = 385/385 (100%)
Query: 1 MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET 60
MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET
Sbjct: 1 MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET 60
Query: 61 SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT 120
SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT
Sbjct: 61 SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT 120
Query: 121 SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA 180
SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA
Sbjct: 121 SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA 180
Query: 181 HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL 240
HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL
Sbjct: 181 HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL 240
Query: 241 TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL 300
TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL
Sbjct: 241 TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL 300
Query: 301 QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED 360
QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED
Sbjct: 301 QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED 360
Query: 361 IRKKVSLGEGRPPVLTASRQGVTST 385
IRKKVSLGEGRPPVLTASRQGVTST
Sbjct: 361 IRKKVSLGEGRPPVLTASRQGVTST 385
>gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]
Length = 659
Score = 722 bits (1863), Expect = 0.0
Identities = 364/365 (99%), Positives = 365/365 (100%)
Query: 1 MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET 60
MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET
Sbjct: 1 MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQET 60
Query: 61 SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT 120
SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT
Sbjct: 61 SSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFT 120
Query: 121 SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA 180
SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA
Sbjct: 121 SPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIA 180
Query: 181 HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL 240
HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL
Sbjct: 181 HLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQL 240
Query: 241 TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL 300
TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL
Sbjct: 241 TSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVEL 300
Query: 301 QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED 360
QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED
Sbjct: 301 QRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDED 360
Query: 361 IRKKV 365
IRKK+
Sbjct: 361 IRKKI 365
>gi|4504901 karyopherin alpha 4 [Homo sapiens]
Length = 521
Score = 44.7 bits (104), Expect = 1e-04
Identities = 67/311 (21%), Positives = 124/311 (39%), Gaps = 20/311 (6%)
Query: 13 RLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIV-LGAVPRLLYLLQQETSSTELKTECAV 71
RL Q V + + +IG+ Q + ++ LG V LL + T L+ V
Sbjct: 164 RLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWV 223
Query: 72 VLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYT 131
++ +L + I+PAL + D+ + + L + T + +
Sbjct: 224 MV-NLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWAL-SYLTDAGNEQIQMVI 281
Query: 132 DATVIPHLMALLSRSRY-TQEYICQIFSHCCKGPDHQT-ILFNHGAVQNIAHLLTSLSYK 189
D+ ++PHL+ LLS Q + + G D QT ++ N A+ + LLT K
Sbjct: 282 DSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEK 341
Query: 190 VRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSA------ 243
+ +A+ S + N Q V ++D L+P I + + D + + A
Sbjct: 342 INKEAVWFLSNITAGNQQ----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTI 397
Query: 244 ----KCLTYMCRAGAIRTDDNCIVLKTLPCL-VRMCSKERLLEERVEGAETLAYLIEPDV 298
+ Y+ + I N + +K + V + +L+ + AET+ LIE
Sbjct: 398 SGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECG 457
Query: 299 ELQRIASITDH 309
L++I + +H
Sbjct: 458 GLEKIEQLQNH 468
>gi|222144293 karyopherin alpha 1 [Homo sapiens]
Length = 538
Score = 41.6 bits (96), Expect = 0.001
Identities = 62/279 (22%), Positives = 107/279 (38%), Gaps = 54/279 (19%)
Query: 29 MKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLL 88
+ N GN+ Q +I GAVP + LL E +++ + LG++A + +L
Sbjct: 151 LTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE--DVQEQAVWALGNIAGDSTMCRDYVL 208
Query: 89 DCHIIPALLQGLLS-------------------------PDLKFIEACLRCLR-TIFTSP 122
DC+I+P LLQ L S P+ + CL L +F S
Sbjct: 209 DCNILPPLLQ-LFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSD 267
Query: 123 VT---------------PEELLYT--DATVIPHLMALLSRSRY-TQEYICQIFSHCCKGP 164
P + + DA V L+ LL + Y + + G
Sbjct: 268 TDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGD 327
Query: 165 DHQT-ILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLP 223
D QT ++ N A+Q++ HLL+S ++ +A S + N T+++ + L+
Sbjct: 328 DIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALIS 387
Query: 224 QIFVKMLQRDKPIEMQLT------SAKCLTYMCRAGAIR 256
+ + K +T SA+ + Y+ G I+
Sbjct: 388 ILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK 426
>gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens]
Length = 493
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Query: 49 VPRLLYLLQQETS-STELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKF 107
+P YLL +S S++ C LG+L + +E + LL I+PAL + SP +
Sbjct: 148 LPATSYLLTYLSSHSSDFIELCLYTLGNLIVESEAVRRQLLPQGIVPALAACIQSPHVAV 207
Query: 108 IEACLRCLRTIFTSPVTPEELL--YTDATVIPHLMALLSRSRYTQEYICQIFSHCCK--- 162
+EA L + + PE+++ +T+ H++ +L + F+ C
Sbjct: 208 LEALGYALSQLLQAEEAPEKIIPSILASTLPQHMLQMLQPGPKLNPGVAVEFAWCLHYII 267
Query: 163 -GPDHQTILFNHGAVQNIAHLLTSLSYKVR 191
+L HGA+ + LL L+ V+
Sbjct: 268 CSQVSNPLLIGHGALSTLGLLLLDLAGAVQ 297
>gi|224589129 karyopherin 7 [Homo sapiens]
Length = 516
Score = 39.3 bits (90), Expect = 0.006
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 8/171 (4%)
Query: 35 GNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIP 94
G+NK+ ++ G +PRL+ L+ +S + T +G++ GT+ + +D ++
Sbjct: 271 GSNKRIGQVVNTGVLPRLVVLM--TSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLN 328
Query: 95 ALLQGLLSPDLKFIEACLRCLRTIFTSPVTP-EELLYTDATVIPHLMALLSRSRY--TQE 151
L Q L + L + P ++LL D V+P L+ALL + +E
Sbjct: 329 VLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYD--VLPPLVALLKNGEFKVQKE 386
Query: 152 YICQIFSHCCKGPDHQTI-LFNHGAVQNIAHLLTSLSYKVRMQALKCFSVL 201
+ + + Q I L + G ++ + +LLT+ K+ + L S +
Sbjct: 387 AVWMVANFATGATMDQLIQLVHSGVLEPLVNLLTAPDVKIVLIILDVISCI 437
>gi|4504897 karyopherin alpha 2 [Homo sapiens]
Length = 529
Score = 38.1 bits (87), Expect = 0.013
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Query: 42 NLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLL 101
N+I G +P+ + L + T + ++ E A L ++A GT K+++D IPA + L
Sbjct: 114 NIIRAGLIPKFVSFLGR-TDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLA 172
Query: 102 SPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLS 144
SP E + L I +L+ V P L+ALL+
Sbjct: 173 SPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDP-LLALLA 214
Score = 33.5 bits (75), Expect = 0.33
Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
Query: 31 NAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDC 90
N V G ++Q +I GA+ LL T ++ E + ++ G ++ ++ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNP--KTNIQKEATWTMSNITAGRQDQIQQVVNH 376
Query: 91 HIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLY-TDATVIPHLMALLS 144
++P L+ L D K + + + T +TS T E+++Y +I LM LL+
Sbjct: 377 GLVPFLVSVLSKADFKTQKEAVWAV-TNYTSGGTVEQIVYLVHCGIIEPLMNLLT 430
>gi|6912478 karyopherin alpha 6 [Homo sapiens]
Length = 536
Score = 37.7 bits (86), Expect = 0.018
Identities = 36/164 (21%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Query: 35 GNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIP 94
G N++ +I G RL+ LL + ++ + +G++ G + + +L+C +P
Sbjct: 282 GPNEKIQAVIDSGVCRRLVELLMH--NDYKVASPALRAVGNIVTGDDIQTQVILNCSALP 339
Query: 95 ALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRY-TQEYI 153
LL L SP + + I T+ + DA + P L+ +L ++ + T++
Sbjct: 340 CLLHLLSSPKESIRKEACWTISNI-TAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEA 398
Query: 154 CQIFSHCCKG--PDHQTILFNHGAVQNIAHLLTSLSYKVRMQAL 195
++ G P+ L + G ++ + LLT + K+ AL
Sbjct: 399 AWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVAL 442
>gi|39812229 karyopherin alpha 5 [Homo sapiens]
Length = 539
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/186 (22%), Positives = 78/186 (41%), Gaps = 8/186 (4%)
Query: 14 LFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVL 73
LF DP + + G N + +I G RL+ LL + ++ + +
Sbjct: 264 LFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMH--NDYKVVSPALRAV 321
Query: 74 GSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKF-IEACLRCLRTIFTSPVTPEELLYTD 132
G++ G + + +L+C +P LL L SP EAC + T+ + D
Sbjct: 322 GNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTV--SNITAGNRAQIQAVID 379
Query: 133 ATVIPHLMALLSRSRY-TQEYICQIFSHCCKG--PDHQTILFNHGAVQNIAHLLTSLSYK 189
A + P L+ +L ++ + T++ ++ G P+ L G ++ + LLT + K
Sbjct: 380 ANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSK 439
Query: 190 VRMQAL 195
+ AL
Sbjct: 440 IVQVAL 445
Score = 35.8 bits (81), Expect = 0.067
Identities = 58/286 (20%), Positives = 112/286 (39%), Gaps = 55/286 (19%)
Query: 43 LIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLS 102
+I GAVP + LL E +++ + LG++A +L+C I+P LL+ L +
Sbjct: 166 VIETGAVPIFIKLLNSEHE--DVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTN 223
Query: 103 ------------------------PDLKFIEACLRCL-RTIFTS-PVTPEELLYT----- 131
P+ + CL L R +F+S P ++ +
Sbjct: 224 SNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLS 283
Query: 132 -----------DATVIPHLMALLSRSRY-TQEYICQIFSHCCKGPDHQT-ILFNHGAVQN 178
D+ V L+ LL + Y + + G D QT ++ N A+
Sbjct: 284 DGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPC 343
Query: 179 IAHLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEM 238
+ HLL+S +R +A S + N + ++D + P + +++LQ+ +
Sbjct: 344 LLHLLSSPKESIRKEACWTVSNITAGN----RAQIQAVIDANIFP-VLIEILQKAE-FRT 397
Query: 239 QLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERV 284
+ +A +T G T + L L C+ +C +++ ++
Sbjct: 398 RKEAAWAITNATSGG---TPEQIRYLVALGCIKPLCDLLTVMDSKI 440
>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
Length = 837
Score = 33.5 bits (75), Expect = 0.33
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 18 DPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLA 77
D Q+ + G + +N V +N K + L VPRLL +L+Q T E K + +L +L+
Sbjct: 410 DVQRAVCGAL--RNLVFEDNDNKLEVAELNGVPRLLQVLKQ-TRDLETKKQITGLLWNLS 466
Query: 78 MGTENNVKSLLDCHIIPALLQGLLSP 103
+ + +K+L+ + L + ++ P
Sbjct: 467 --SNDKLKNLMITEALLTLTENIIIP 490
>gi|34485722 karyopherin alpha 3 [Homo sapiens]
Length = 521
Score = 33.1 bits (74), Expect = 0.43
Identities = 27/114 (23%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
Query: 35 GNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIP 94
G N+Q +I G VP L+ LL + +++T +G++ GT+ + +L+C ++
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQ--EVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLS 329
Query: 95 ALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRY 148
L P K + + L I T+ + DA +IP ++ L++ +
Sbjct: 330 HFPNLLSHPKEKINKEAVWFLSNI-TAGNQQQVQAVIDAGLIPMIIHQLAKGDF 382
>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
Length = 872
Score = 32.7 bits (73), Expect = 0.57
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 156 IFSHCCKGPDHQTILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFEN 205
I+ KG +++T L GAV+ + LLT VR A F +LA N
Sbjct: 49 IYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNN 98
>gi|197333755 interferon-related developmental regulator 2 [Homo
sapiens]
Length = 506
Score = 32.7 bits (73), Expect = 0.57
Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 31/89 (34%)
Query: 50 PRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIE 109
P L+ +L T+S + CA LG L C++ A +Q L+S
Sbjct: 228 PLLVSVLSDSTASPAARLHCASALG-------------LGCYVAAADIQDLVS------- 267
Query: 110 ACLRCLRTIF----------TSPVTPEEL 128
CL CL ++F TSPV P L
Sbjct: 268 -CLACLESVFSRFYGLGGSSTSPVVPASL 295
>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
Length = 3056
Score = 31.2 bits (69), Expect = 1.6
Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 188 YKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLT 247
+ VRM + C L +P ++NV+ + ++F + L D ++++ +A+ +
Sbjct: 1036 FSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFL-ADNHHQVRMLAAESIN 1094
Query: 248 YMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASIT 307
R D+ +LK LP ++ + E + EG +++ E L I +
Sbjct: 1095 ---RLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRK 1151
Query: 308 DHLIAMLA 315
L+ ++A
Sbjct: 1152 SVLLTLIA 1159
>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, partial
[Homo sapiens]
Length = 2934
Score = 31.2 bits (69), Expect = 1.6
Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 188 YKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLT 247
+ VRM + C L +P ++NV+ + ++F + L D ++++ +A+ +
Sbjct: 914 FSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFL-ADNHHQVRMLAAESIN 972
Query: 248 YMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASIT 307
R D+ +LK LP ++ + E + EG +++ E L I +
Sbjct: 973 ---RLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIYNRK 1029
Query: 308 DHLIAMLA 315
L+ ++A
Sbjct: 1030 SVLLTLIA 1037
>gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5
[Homo sapiens]
Length = 558
Score = 30.8 bits (68), Expect = 2.1
Identities = 20/67 (29%), Positives = 31/67 (46%)
Query: 11 VDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECA 70
V L D + +LQ + N ++ +A LI +G +P L+ LL + L C
Sbjct: 95 VQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCL 154
Query: 71 VVLGSLA 77
V G+LA
Sbjct: 155 VAFGNLA 161
>gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4
[Homo sapiens]
Length = 559
Score = 30.8 bits (68), Expect = 2.1
Identities = 20/67 (29%), Positives = 31/67 (46%)
Query: 11 VDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECA 70
V L D + +LQ + N ++ +A LI +G +P L+ LL + L C
Sbjct: 96 VQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCL 155
Query: 71 VVLGSLA 77
V G+LA
Sbjct: 156 VAFGNLA 162
>gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3
[Homo sapiens]
Length = 607
Score = 30.4 bits (67), Expect = 2.8
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 16 DPDPQKVLQGVIDM-KNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLG 74
DP +K+L M N N+ +A LI +G +P L+ LL + L C V G
Sbjct: 148 DPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFG 207
Query: 75 SLA 77
+LA
Sbjct: 208 NLA 210
>gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2
[Homo sapiens]
Length = 607
Score = 30.4 bits (67), Expect = 2.8
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 16 DPDPQKVLQGVIDM-KNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLG 74
DP +K+L M N N+ +A LI +G +P L+ LL + L C V G
Sbjct: 149 DPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFG 208
Query: 75 SLA 77
+LA
Sbjct: 209 NLA 211
>gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1
[Homo sapiens]
Length = 608
Score = 30.4 bits (67), Expect = 2.8
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 16 DPDPQKVLQGVIDM-KNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLG 74
DP +K+L M N N+ +A LI +G +P L+ LL + L C V G
Sbjct: 149 DPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFG 208
Query: 75 SLA 77
+LA
Sbjct: 209 NLA 211
>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
Length = 352
Score = 30.0 bits (66), Expect = 3.7
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 218 DGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAI 255
DGE+L +I K +R + I Q T CL + RAG +
Sbjct: 316 DGEVLEEIVTK--ERHREINKQATRGDCLAFQMRAGLL 351
>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
Length = 341
Score = 30.0 bits (66), Expect = 3.7
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 218 DGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAI 255
DGE+L +I K +R + I Q T CL + RAG +
Sbjct: 305 DGEVLEEIVTK--ERHREINKQATRGDCLAFQMRAGLL 340
>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
Length = 360
Score = 30.0 bits (66), Expect = 3.7
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 218 DGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAI 255
DGE+L +I K +R + I Q T CL + RAG +
Sbjct: 324 DGEVLEEIVTK--ERHREINKQATRGDCLAFQMRAGLL 359
>gi|42558270 HEAT repeat containing 4 [Homo sapiens]
Length = 979
Score = 29.6 bits (65), Expect = 4.8
Identities = 19/80 (23%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 169 ILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVK 228
I ++H V+N+ L L VR++A+ + A E P+++ + + + LP++ +
Sbjct: 426 IEWHHETVENLLQSLGDLHDDVRIKAITTCATAALERPRIATSQRDSDKTIQDLPEVLLP 485
Query: 229 MLQR---DKPIEMQLTSAKC 245
L+ DK +++ +A C
Sbjct: 486 ALEAALCDKNAHVRMAAAIC 505
>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
Length = 719
Score = 29.6 bits (65), Expect = 4.8
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 92 IIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSR 147
++PALL L D + + A L LR + P P LL A + P L LL +R
Sbjct: 441 LLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLL--SAELGPRLPPLLDDTR 494
>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
Length = 1044
Score = 29.3 bits (64), Expect = 6.3
Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 9/86 (10%)
Query: 142 LLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSLSYKVRMQAL-----K 196
L S + QE+ C + + + ++ HG ++ +A LL + K R+ A+ K
Sbjct: 682 LNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWK 741
Query: 197 CF----SVLAFENPQVSMTLVNVLVD 218
C +V F + TLV +L D
Sbjct: 742 CSISKENVTKFREYKAIETLVGLLTD 767
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 28.9 bits (63), Expect = 8.2
Identities = 20/65 (30%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 319 KYPSSVSAITDIKRLD-HDLKHAHELRQAAFKLYASLGANDEDIRKKVSLGEGRPPVLTA 377
+Y S++ I ++R++ DL+ A +L++ + GA+ +R VS+ PPV+T
Sbjct: 29427 EYSESIAEIEPVERIEIPDLELADDLKKT---VTIRAGAS---LRLMVSVSGRPPPVITW 29480
Query: 378 SRQGV 382
S+QG+
Sbjct: 29481 SKQGI 29485
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 28.9 bits (63), Expect = 8.2
Identities = 20/65 (30%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 319 KYPSSVSAITDIKRLD-HDLKHAHELRQAAFKLYASLGANDEDIRKKVSLGEGRPPVLTA 377
+Y S++ I ++R++ DL+ A +L++ + GA+ +R VS+ PPV+T
Sbjct: 23122 EYSESIAEIEPVERIEIPDLELADDLKKT---VTIRAGAS---LRLMVSVSGRPPPVITW 23175
Query: 378 SRQGV 382
S+QG+
Sbjct: 23176 SKQGI 23180
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 28.9 bits (63), Expect = 8.2
Identities = 20/65 (30%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 319 KYPSSVSAITDIKRLD-HDLKHAHELRQAAFKLYASLGANDEDIRKKVSLGEGRPPVLTA 377
+Y S++ I ++R++ DL+ A +L++ + GA+ +R VS+ PPV+T
Sbjct: 23055 EYSESIAEIEPVERIEIPDLELADDLKKT---VTIRAGAS---LRLMVSVSGRPPPVITW 23108
Query: 378 SRQGV 382
S+QG+
Sbjct: 23109 SKQGI 23113
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,378,663
Number of Sequences: 37866
Number of extensions: 536541
Number of successful extensions: 1330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1305
Number of HSP's gapped (non-prelim): 43
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.