BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sapiens] (464 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sap... 959 0.0 gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ... 417 e-116 gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei... 414 e-115 gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein... 414 e-115 gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2 ... 303 2e-82 gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2 ... 252 6e-67 gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sap... 204 2e-52 gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Ho... 177 2e-44 gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Ho... 135 1e-31 gi|148231468 GDNF family receptor alpha like [Homo sapiens] 70 4e-12 gi|148886654 polydom [Homo sapiens] 36 0.085 gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 33 0.42 gi|21264361 mannan-binding lectin serine protease 2 isoform 2 pr... 33 0.42 gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] 33 0.42 gi|39930511 collagen and calcium binding EGF domains 1 [Homo sap... 33 0.42 gi|42476320 sushi domain containing 1 [Homo sapiens] 32 1.2 gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 31 2.1 gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 31 2.1 gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 31 2.1 gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap... 31 2.7 gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 31 2.7 gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3... 30 3.6 gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1 ... 30 3.6 gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] 30 3.6 gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens] 30 3.6 gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 30 3.6 gi|4557841 recombination activating gene 1 [Homo sapiens] 30 4.6 gi|83367077 mucin 16 [Homo sapiens] 30 4.6 gi|11863156 RECK protein precursor [Homo sapiens] 30 4.6 gi|239744133 PREDICTED: hypothetical protein [Homo sapiens] 30 6.1 >gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sapiens] Length = 464 Score = 959 bits (2480), Expect = 0.0 Identities = 464/464 (100%), Positives = 464/464 (100%) Query: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL Sbjct: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60 Query: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE Sbjct: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120 Query: 121 EFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSS 180 EFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSS Sbjct: 121 EFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSS 180 Query: 181 YISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPS 240 YISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPS Sbjct: 181 YISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPS 240 Query: 241 CSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGM 300 CSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGM Sbjct: 241 CSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGM 300 Query: 301 IGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTD 360 IGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTD Sbjct: 301 IGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTD 360 Query: 361 VNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSM 420 VNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSM Sbjct: 361 VNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSM 420 Query: 421 CFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL 464 CFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL Sbjct: 421 CFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL 464 >gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein [Homo sapiens] Length = 465 Score = 417 bits (1072), Expect = e-116 Identities = 208/396 (52%), Positives = 275/396 (69%), Gaps = 16/396 (4%) Query: 38 VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92 +DCV+A++ C E +CS++YRTLRQC+AG++ N LA+ EC++A+E L++ LY+ Sbjct: 27 LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86 Query: 93 CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADP 152 CRCKRGMKKE CL+IYWS++ L +G + E SPYEPV SRLSDIFR+ S Sbjct: 87 CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFISDVFQQV 145 Query: 153 VVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVP 212 K N+CLDAAKACNL+D CKK RS+YI+ C +S + CNRRKCHKALRQFFD+VP Sbjct: 146 EHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVS-NDVCNRRKCHKALRQFFDKVP 204 Query: 213 SEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFH 272 ++++Y MLFCSC+D AC ERRRQTI+P CSYE++EKPNCL+L+ C+T+++CRSRLADF Sbjct: 205 AKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFF 264 Query: 273 ANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332 NC+ ++V+SC +NY CL +Y+G+IG MTPNY+DSS + V+PWC C SGN Sbjct: 265 TNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSS--SLSVAPWCDCSNSGNDL 322 Query: 333 EECEKFLRDFTENPCLRNAIQAFGNGTDVNV-SPKGP----SFQATQAPRVEKTPSLPDD 387 EEC KFL F +N CL+NAIQAFGNG+DV V P P + T A RV+ P P Sbjct: 323 EECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPVQTTTATTTTALRVKNKPLGP-- 380 Query: 388 LSDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFT 423 + T V+ C ++Q Q LK+N S +C + Sbjct: 381 AGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCIS 416 >gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein [Homo sapiens] Length = 460 Score = 414 bits (1063), Expect = e-115 Identities = 208/396 (52%), Positives = 275/396 (69%), Gaps = 21/396 (5%) Query: 38 VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92 +DCV+A++ C E +CS++YRTLRQC+AG++ N LA+ EC++A+E L++ LY+ Sbjct: 27 LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86 Query: 93 CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADP 152 CRCKRGMKKE CL+IYWS++ L +G + E SPYEPV SRLSDIFR+ S Sbjct: 87 CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFISVEHIP- 144 Query: 153 VVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVP 212 K N+CLDAAKACNL+D CKK RS+YI+ C +S + CNRRKCHKALRQFFD+VP Sbjct: 145 ----KGNNCLDAAKACNLDDICKKYRSAYITPCTTSVS-NDVCNRRKCHKALRQFFDKVP 199 Query: 213 SEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFH 272 ++++Y MLFCSC+D AC ERRRQTI+P CSYE++EKPNCL+L+ C+T+++CRSRLADF Sbjct: 200 AKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFF 259 Query: 273 ANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332 NC+ ++V+SC +NY CL +Y+G+IG MTPNY+DSS + V+PWC C SGN Sbjct: 260 TNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSS--SLSVAPWCDCSNSGNDL 317 Query: 333 EECEKFLRDFTENPCLRNAIQAFGNGTDVNV-SPKGP----SFQATQAPRVEKTPSLPDD 387 EEC KFL F +N CL+NAIQAFGNG+DV V P P + T A RV+ P P Sbjct: 318 EECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPVQTTTATTTTALRVKNKPLGP-- 375 Query: 388 LSDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFT 423 + T V+ C ++Q Q LK+N S +C + Sbjct: 376 AGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCIS 411 >gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein [Homo sapiens] Length = 460 Score = 414 bits (1063), Expect = e-115 Identities = 208/396 (52%), Positives = 275/396 (69%), Gaps = 21/396 (5%) Query: 38 VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92 +DCV+A++ C E +CS++YRTLRQC+AG++ N LA+ EC++A+E L++ LY+ Sbjct: 27 LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86 Query: 93 CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADP 152 CRCKRGMKKE CL+IYWS++ L +G + E SPYEPV SRLSDIFR+ S Sbjct: 87 CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFISVEHIP- 144 Query: 153 VVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVP 212 K N+CLDAAKACNL+D CKK RS+YI+ C +S + CNRRKCHKALRQFFD+VP Sbjct: 145 ----KGNNCLDAAKACNLDDICKKYRSAYITPCTTSVS-NDVCNRRKCHKALRQFFDKVP 199 Query: 213 SEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFH 272 ++++Y MLFCSC+D AC ERRRQTI+P CSYE++EKPNCL+L+ C+T+++CRSRLADF Sbjct: 200 AKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFF 259 Query: 273 ANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332 NC+ ++V+SC +NY CL +Y+G+IG MTPNY+DSS + V+PWC C SGN Sbjct: 260 TNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSS--SLSVAPWCDCSNSGNDL 317 Query: 333 EECEKFLRDFTENPCLRNAIQAFGNGTDVNV-SPKGP----SFQATQAPRVEKTPSLPDD 387 EEC KFL F +N CL+NAIQAFGNG+DV V P P + T A RV+ P P Sbjct: 318 EECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPVQTTTATTTTALRVKNKPLGP-- 375 Query: 388 LSDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFT 423 + T V+ C ++Q Q LK+N S +C + Sbjct: 376 AGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCIS 411 >gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2 [Homo sapiens] Length = 364 Score = 303 bits (776), Expect = 2e-82 Identities = 146/146 (100%), Positives = 146/146 (100%) Query: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL Sbjct: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60 Query: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE Sbjct: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120 Query: 121 EFYEASPYEPVTSRLSDIFRLASIFS 146 EFYEASPYEPVTSRLSDIFRLASIFS Sbjct: 121 EFYEASPYEPVTSRLSDIFRLASIFS 146 >gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2 [Homo sapiens] Length = 140 Score = 252 bits (643), Expect = 6e-67 Identities = 123/140 (87%), Positives = 125/140 (89%) Query: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL Sbjct: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60 Query: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTE E Sbjct: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEAE 120 Query: 121 EFYEASPYEPVTSRLSDIFR 140 + E +L FR Sbjct: 121 FSLKGEVSEVTELQLKPNFR 140 >gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sapiens] Length = 400 Score = 204 bits (518), Expect = 2e-52 Identities = 116/323 (35%), Positives = 164/323 (50%), Gaps = 27/323 (8%) Query: 40 CVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKE------CQAALEVLQESPLYDC 93 C++A C A+ CS+ Y L C + +T L ++E C A + L+ S L C Sbjct: 44 CLQARRKCQADPTCSAAYHHLDSCTSSI--STPLPSEEPSVPADCLEAAQQLRNSSLIGC 101 Query: 94 RCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPV 153 C R MK ++ CL IYW++H + G + SPYE + L+ + + Sbjct: 102 MCHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSKPWKMNLSKL-------NM 154 Query: 154 VSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPS 213 + S+ CL A C LND C +LR +Y C+ C R C + L FF++ Sbjct: 155 LKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACS-----GPHCQRHVCLRQLLTFFEKAAE 209 Query: 214 EYTYRMLFCSC--QDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADF 271 + +L C C D+ C ERRR TI P+C+ PNCL+LR +C +D LCRSRL DF Sbjct: 210 PHAQGLLLCPCAPNDRGCGERRRNTIAPNCAL-PPVAPNCLELRRLCFSDPLCRSRLVDF 268 Query: 272 HANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNM 331 +C + A CL +Y G+IG MTPN+V + T + +S C+CRGSGN+ Sbjct: 269 QTHCHP--MDILGTCATEQSRCLRAYLGLIGTAMTPNFVSNVNTSVALS--CTCRGSGNL 324 Query: 332 EEECEKFLRDFTENPCLRNAIQA 354 +EECE F+ NPCL AI A Sbjct: 325 QEECEMLEGFFSHNPCLTEAIAA 347 >gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Homo sapiens] Length = 269 Score = 177 bits (449), Expect = 2e-44 Identities = 88/206 (42%), Positives = 117/206 (56%), Gaps = 5/206 (2%) Query: 155 SAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSE 214 S N C+DAA+AC + C++LRS Y++ C + C R +C +ALR+FF R P Sbjct: 20 SVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGG-CPRARCRRALRRFFARGPPA 78 Query: 215 YTYRMLFCSCQDQACAERRRQTILPSCSYE--DKEKPNCLDLRGVCRTDHLCRSRLADFH 272 T+ +LFC C ACAERRRQT +PSC++ P+CL+ C +CR RL F Sbjct: 79 LTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQ 138 Query: 273 ANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332 +C + C D CL +YAG++G +TPNYVD+ V+PWC C SGN Sbjct: 139 VSCTPAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDN--VSARVAPWCDCGASGNRR 196 Query: 333 EECEKFLRDFTENPCLRNAIQAFGNG 358 E+CE F FT N CL AIQAF +G Sbjct: 197 EDCEAFRGLFTRNRCLDGAIQAFASG 222 >gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Homo sapiens] Length = 299 Score = 135 bits (339), Expect = 1e-31 Identities = 85/236 (36%), Positives = 111/236 (47%), Gaps = 35/236 (14%) Query: 155 SAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSE 214 S N C+DAA+AC + C++LRS Y++ C + C R +C +ALR+FF R P Sbjct: 20 SVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGG-CPRARCRRALRRFFARGPPA 78 Query: 215 YTYRMLFCSCQDQACAERRRQTILPSCSYE--DKEKPNCLDLRGVCRTDHLCRSR----- 267 T+ +LFC C ACAERRRQT +PSC++ P+CL+ C +CR Sbjct: 79 LTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRCARAAAG 138 Query: 268 --------LADFHANCRA-------------SYQTVTSCPADNYQACLGSYAG----MIG 302 L+ H A S Q PA + G G Sbjct: 139 PWRGWGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAGPGRPLPARLRGPRGVPAG 198 Query: 303 FDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNG 358 +TPNYVD+ V+PWC C SGN E+CE F FT N CL AIQAF +G Sbjct: 199 TAVTPNYVDN--VSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASG 252 >gi|148231468 GDNF family receptor alpha like [Homo sapiens] Length = 394 Score = 70.1 bits (170), Expect = 4e-12 Identities = 51/196 (26%), Positives = 81/196 (41%), Gaps = 19/196 (9%) Query: 161 CLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRML 220 CL+ A+AC + C +SY+ C+ +P C+ ++C A+R F+ +P + Sbjct: 131 CLEVAEACVGDVVCNAQLASYLKACSANGNP---CDLKQCQAAIRFFYQNIPFNIAQMLA 187 Query: 221 FCSC--QDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRAS 278 FC C D C + + +C+ P CL + C+ D LCR F + C Sbjct: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKC--- 244 Query: 279 YQTVT-SCPADNYQACLGSYAGMI-----GFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332 +Q VT C D + C+ + + D Y+D G V+ C+CR E Sbjct: 245 WQRVTRKCHED--ENCISTLSKQDLTCSGSDDCKAAYIDI--LGTVLQVQCTCRTITQSE 300 Query: 333 EE-CEKFLRDFTENPC 347 E C+ F C Sbjct: 301 ESLCKIFQHMLHRKSC 316 >gi|148886654 polydom [Homo sapiens] Length = 3571 Score = 35.8 bits (81), Expect = 0.085 Identities = 35/131 (26%), Positives = 47/131 (35%), Gaps = 21/131 (16%) Query: 212 PSEYTYRMLFCSCQDQACAERRRQTILPS----------CSYEDKEKPNCLDLRGVCRTD 261 P E +L + +A A R LPS CSY E +C D G C+ Sbjct: 238 PKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCK-- 295 Query: 262 HLCRSRLADFHANCRASY------QTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPT 315 C + F C Y T+CP+ Y+ GS G+ P+ +SP Sbjct: 296 --CGTHTGHFECICEKGYYGKGLQYECTACPSGTYKP-EGSPGGISSCIPCPDENHTSPP 352 Query: 316 GIVVSPWCSCR 326 G C CR Sbjct: 353 GSTSPEDCVCR 363 >gi|21264363 mannan-binding lectin serine protease 2 isoform 1 precursor [Homo sapiens] Length = 686 Score = 33.5 bits (75), Expect = 0.42 Identities = 25/98 (25%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 183 SICNREISPTERCNRRKCHKALRQFFD-RVPSEYTYRMLFCSCQDQACAERRRQTILPSC 241 ++C +E + TER + +L D S+Y+ F + AE + C Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED-----IDEC 142 Query: 242 SYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASY 279 E P C DH C + L F+ +CRA Y Sbjct: 143 QVAPGEAPTC---------DHHCHNHLGGFYCSCRAGY 171 >gi|21264361 mannan-binding lectin serine protease 2 isoform 2 precursor [Homo sapiens] Length = 185 Score = 33.5 bits (75), Expect = 0.42 Identities = 25/98 (25%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 183 SICNREISPTERCNRRKCHKALRQFFD-RVPSEYTYRMLFCSCQDQACAERRRQTILPSC 241 ++C +E + TER + +L D S+Y+ F + AE + C Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED-----IDEC 142 Query: 242 SYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASY 279 E P C DH C + L F+ +CRA Y Sbjct: 143 QVAPGEAPTC---------DHHCHNHLGGFYCSCRAGY 171 >gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] Length = 375 Score = 33.5 bits (75), Expect = 0.42 Identities = 37/180 (20%), Positives = 64/180 (35%), Gaps = 17/180 (9%) Query: 158 SNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTY 217 S C +++ + + +C+ R+S S + + C+ C + R + + Sbjct: 107 STCCCQSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCS---CQTS-RTSSTSCSYQSSR 162 Query: 218 RMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLR--GVCRTDHLCRSRLADFHANC 275 CSCQ T SC+++ + + G T + C+S +C Sbjct: 163 TSSTCSCQSSG-------TSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSC 215 Query: 276 RASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEEC 335 ++S + TSC + G T SS T S CSC+ SG C Sbjct: 216 QSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRT----SSTCSCQSSGTSSTSC 271 >gi|39930511 collagen and calcium binding EGF domains 1 [Homo sapiens] Length = 406 Score = 33.5 bits (75), Expect = 0.42 Identities = 24/115 (20%), Positives = 42/115 (36%), Gaps = 28/115 (24%) Query: 185 CNREISPTERCNRRKCHKALRQFFDR-VPSEY--------------TYRMLFCSCQDQAC 229 C + C R+KC K + + +P +Y + + C+C Sbjct: 59 CLKSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYR 118 Query: 230 AERRRQTILPSCSYEDKEKPNCLDLRGVCRTD-----HLCRSRLADFHANCRASY 279 +R R + +EKP CLD+ ++ H+C + L + CR Y Sbjct: 119 YDRER--------HRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGY 165 >gi|42476320 sushi domain containing 1 [Homo sapiens] Length = 747 Score = 32.0 bits (71), Expect = 1.2 Identities = 42/190 (22%), Positives = 63/190 (33%), Gaps = 35/190 (18%) Query: 162 LDAAKACNLNDNCKKLRSSYISICNREI---SPTERCNRRKCH-KALRQFFDRVPSEYTY 217 LD C+ + C++ I ICN T+ ++ +C A + T Sbjct: 36 LDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTP 95 Query: 218 RMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRA 277 +C C + A +T +P+ + C ++ G+CR C + F C Sbjct: 96 GGFYCICLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYCMD 154 Query: 278 SY------------QTVTSCP---------------ADNYQACLGS---YAGMIGFDMTP 307 Y TSC NY + LGS YA GF P Sbjct: 155 GYLPRNGPEPFHPTTDATSCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVP 214 Query: 308 NYVDSSPTGI 317 SS TG+ Sbjct: 215 EDTVSSCTGL 224 >gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] Length = 1539 Score = 31.2 bits (69), Expect = 2.1 Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 4/108 (3%) Query: 334 ECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTS 393 + +K L DF +NP ++ +Q N D N ++Q R P + ++ S Sbjct: 11 DLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQ--RTSLLPKDQECVNSCAS 68 Query: 394 LGTSVITTCTSVQEQGLKANNS--KELSMCFTELTTNIIPGSNKVIKP 439 TS T +S+ E+ LK S E ++ +L +++ G++ I+P Sbjct: 69 SETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQP 116 >gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] Length = 1539 Score = 31.2 bits (69), Expect = 2.1 Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 4/108 (3%) Query: 334 ECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTS 393 + +K L DF +NP ++ +Q N D N ++Q R P + ++ S Sbjct: 11 DLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQ--RTSLLPKDQECVNSCAS 68 Query: 394 LGTSVITTCTSVQEQGLKANNS--KELSMCFTELTTNIIPGSNKVIKP 439 TS T +S+ E+ LK S E ++ +L +++ G++ I+P Sbjct: 69 SETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQP 116 >gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] Length = 988 Score = 31.2 bits (69), Expect = 2.1 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Query: 246 KEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVT 283 K+ CL G C DH CR+ + F CR Y+ +T Sbjct: 281 KDINECLVNNGGC--DHFCRNTVGSFECGCRKGYKLLT 316 >gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens] Length = 1235 Score = 30.8 bits (68), Expect = 2.7 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 5/106 (4%) Query: 250 NCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNY 309 +C +CR CR R F +C S T C ++ A GS + +I ++ NY Sbjct: 888 HCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFC-SNEISAYFGSGSSVI-YNFQENY 945 Query: 310 VDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAF 355 + S + S S G + E KF T P L + +F Sbjct: 946 LLSKNSS---SHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSF 988 >gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens] Length = 1308 Score = 30.8 bits (68), Expect = 2.7 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 5/106 (4%) Query: 250 NCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNY 309 +C +CR CR R F +C S T C ++ A GS + +I ++ NY Sbjct: 961 HCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFC-SNEISAYFGSGSSVI-YNFQENY 1018 Query: 310 VDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAF 355 + S + S S G + E KF T P L + +F Sbjct: 1019 LLSKNSS---SHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSF 1061 >gi|38202241 WNT1 inducible signaling pathway protein 3 isoform 3 [Homo sapiens] Length = 372 Score = 30.4 bits (67), Expect = 3.6 Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 41/180 (22%) Query: 83 EVLQESPLYDCRCKRGMKKELQCLQIY----WSIHLGLTEGEEFYEAS--PYEPVTSRLS 136 +V Q +PL+ C C G + C ++ H +G + + S EP+ +LS Sbjct: 151 QVFQPNPLFSCLCVSG---AIGCTPLFIPKLAGSHCSGAKGGKKSDQSNCSLEPLLQQLS 207 Query: 137 DIFRLASIFSGTGADPVVSAKSNHCLDAA----------------KACNLNDNC---KKL 177 ++ + P++ K CL A + N N NC K+ Sbjct: 208 TSYKTMPAYRNL---PLIWKKK--CLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK 262 Query: 178 RSSYISICNREISPTERCNRRK-------CHKALRQFFDRVPSEYTYRMLFCS-CQDQAC 229 R YI C+ I T + + K KA + F S +Y+ FC C D+ C Sbjct: 263 RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC 322 >gi|4507925 WNT1 inducible signaling pathway protein 3 isoform 1 [Homo sapiens] Length = 354 Score = 30.4 bits (67), Expect = 3.6 Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 41/180 (22%) Query: 83 EVLQESPLYDCRCKRGMKKELQCLQIY----WSIHLGLTEGEEFYEAS--PYEPVTSRLS 136 +V Q +PL+ C C G + C ++ H +G + + S EP+ +LS Sbjct: 133 QVFQPNPLFSCLCVSG---AIGCTPLFIPKLAGSHCSGAKGGKKSDQSNCSLEPLLQQLS 189 Query: 137 DIFRLASIFSGTGADPVVSAKSNHCLDAA----------------KACNLNDNC---KKL 177 ++ + P++ K CL A + N N NC K+ Sbjct: 190 TSYKTMPAYRNL---PLIWKKK--CLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK 244 Query: 178 RSSYISICNREISPTERCNRRK-------CHKALRQFFDRVPSEYTYRMLFCS-CQDQAC 229 R YI C+ I T + + K KA + F S +Y+ FC C D+ C Sbjct: 245 RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC 304 >gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] Length = 451 Score = 30.4 bits (67), Expect = 3.6 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 18/86 (20%) Query: 362 NVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITT----------CTSVQEQGLK 411 N+ P S AP+++ P D DST+LGT T CT+ + +GLK Sbjct: 54 NLRPAAAS-AVRSAPQLQPDPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLK 112 Query: 412 --ANNSKELSMCFTELTTNIIPGSNK 435 A+ S + + N++PG++K Sbjct: 113 PLASGSAD-----AYVKANLLPGASK 133 >gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens] Length = 451 Score = 30.4 bits (67), Expect = 3.6 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 18/86 (20%) Query: 362 NVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITT----------CTSVQEQGLK 411 N+ P S AP+++ P D DST+LGT T CT+ + +GLK Sbjct: 54 NLRPAAAS-AVRSAPQLQPDPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLK 112 Query: 412 --ANNSKELSMCFTELTTNIIPGSNK 435 A+ S + + N++PG++K Sbjct: 113 PLASGSAD-----AYVKANLLPGASK 133 >gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sapiens] Length = 431 Score = 30.4 bits (67), Expect = 3.6 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 18/86 (20%) Query: 362 NVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITT----------CTSVQEQGLK 411 N+ P S AP+++ P D DST+LGT T CT+ + +GLK Sbjct: 108 NLRPAAAS-AVRSAPQLQPDPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLK 166 Query: 412 --ANNSKELSMCFTELTTNIIPGSNK 435 A+ S + + N++PG++K Sbjct: 167 PLASGSAD-----AYVKANLLPGASK 187 >gi|4557841 recombination activating gene 1 [Homo sapiens] Length = 1043 Score = 30.0 bits (66), Expect = 4.6 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 2/88 (2%) Query: 185 CNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYE 244 CN E+S + + HK ++ F + R S +A R R+ L ++ Sbjct: 363 CNEEVSLEKYNHHISSHKESKEIFVHINKGGRPRQHLLSLTRRAQKHRLRELKLQVKAFA 422 Query: 245 DKEKPNCLDLRGVCRTDHLCRSRLADFH 272 DKE+ D++ VC T L R + H Sbjct: 423 DKEEGG--DVKSVCMTLFLLALRARNEH 448 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 30.0 bits (66), Expect = 4.6 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 9/100 (9%) Query: 360 DVNVSPKGPSFQATQAPRVEKTPSL-PDDLSDSTSLGTSVITTCTSVQEQGLKANNSKEL 418 D V P+F T+ E T SL P STS T+ IT TS G+ + + E+ Sbjct: 9851 DTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITE-TSAVLYGVPTSATTEV 9909 Query: 419 SMCFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVL 458 SM TE+ + SN++ P+S S P V++ L Sbjct: 9910 SM--TEIMS-----SNRIHIPDSDQSTMSPDIITEVITRL 9942 Score = 29.6 bits (65), Expect = 6.1 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Query: 359 TDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNS-KE 417 T + V+ GP +T A V TPS + + S S T T++ K +S + Sbjct: 2217 TSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRT 2276 Query: 418 LSMCFTELTTNI--IPGSNKVIKPNSGPSRARPSAAL 452 +S ELT+ + IPG ++ P+ A PS L Sbjct: 2277 ISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITL 2313 >gi|11863156 RECK protein precursor [Homo sapiens] Length = 971 Score = 30.0 bits (66), Expect = 4.6 Identities = 27/105 (25%), Positives = 39/105 (37%), Gaps = 15/105 (14%) Query: 160 HCLDAAKACNLNDNCKKLRSSYISICN--REISPTERCNRRKCHKALRQFFDRVPSEYTY 217 HC+D K+C + K +S+ CN + C+ R C DR T+ Sbjct: 573 HCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSEDDR----RTF 628 Query: 218 RMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDH 262 L C+C DQ +P C + P+ R V DH Sbjct: 629 TGLPCNCADQ---------FVPVCGQNGRTYPSACIARCVGLQDH 664 >gi|239744133 PREDICTED: hypothetical protein [Homo sapiens] Length = 375 Score = 29.6 bits (65), Expect = 6.1 Identities = 27/116 (23%), Positives = 40/116 (34%), Gaps = 13/116 (11%) Query: 222 CSCQDQACAERRRQTILPSCSYEDKEKPNCLDLR--GVCRTDHLCRSRLADFHANCRASY 279 CSCQ T SC+++ + + G T + C+S +C++S Sbjct: 167 CSCQSSG-------TSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSG 219 Query: 280 QTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEEC 335 + TSC + G T SS T S CSC+ S C Sbjct: 220 TSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRT----SSTCSCQSSRTSSTSC 271 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.132 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,973,967 Number of Sequences: 37866 Number of extensions: 896335 Number of successful extensions: 2236 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 2172 Number of HSP's gapped (non-prelim): 57 length of query: 464 length of database: 18,247,518 effective HSP length: 106 effective length of query: 358 effective length of database: 14,233,722 effective search space: 5095672476 effective search space used: 5095672476 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.